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Database: PDB
Entry: 1FOS
LinkDB: 1FOS
Original site: 1FOS 
HEADER    TRANSCRIPTION/DNA                       07-MAR-95   1FOS              
TITLE     TWO HUMAN C-FOS:C-JUN:DNA COMPLEXES                                   
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: DNA (5'-                                                   
COMPND   3 D(*AP*AP*TP*GP*GP*AP*TP*GP*AP*GP*TP*CP*AP*TP*AP*GP*GP*AP*GP          
COMPND   4 *A)-3');                                                             
COMPND   5 CHAIN: A, C;                                                         
COMPND   6 ENGINEERED: YES;                                                     
COMPND   7 MOL_ID: 2;                                                           
COMPND   8 MOLECULE: DNA (5'-                                                   
COMPND   9 D(*TP*TP*CP*TP*CP*CP*TP*AP*TP*GP*AP*CP*TP*CP*AP*TP*CP*CP*AP          
COMPND  10 *T)-3');                                                             
COMPND  11 CHAIN: B, D;                                                         
COMPND  12 ENGINEERED: YES;                                                     
COMPND  13 MOL_ID: 3;                                                           
COMPND  14 MOLECULE: P55-C-FOS PROTO-ONCOGENE PROTEIN;                          
COMPND  15 CHAIN: E, G;                                                         
COMPND  16 SYNONYM: CELLULAR ONCOGENE C-FOS, G0S7 PROTEIN;                      
COMPND  17 ENGINEERED: YES;                                                     
COMPND  18 MOL_ID: 4;                                                           
COMPND  19 MOLECULE: C-JUN PROTO-ONCOGENE PROTEIN;                              
COMPND  20 CHAIN: F, H;                                                         
COMPND  21 ENGINEERED: YES                                                      
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 SYNTHETIC: YES;                                                      
SOURCE   3 MOL_ID: 2;                                                           
SOURCE   4 SYNTHETIC: YES;                                                      
SOURCE   5 MOL_ID: 3;                                                           
SOURCE   6 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE   7 ORGANISM_COMMON: HUMAN;                                              
SOURCE   8 ORGANISM_TAXID: 9606;                                                
SOURCE   9 EXPRESSION_SYSTEM: ESCHERICHIA COLI;                                 
SOURCE  10 EXPRESSION_SYSTEM_TAXID: 562;                                        
SOURCE  11 EXPRESSION_SYSTEM_STRAIN: BL21/DE3/PLYSS;                            
SOURCE  12 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                              
SOURCE  13 EXPRESSION_SYSTEM_PLASMID: PJUN(S)63;                                
SOURCE  14 MOL_ID: 4;                                                           
SOURCE  15 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  16 ORGANISM_COMMON: HUMAN;                                              
SOURCE  17 ORGANISM_TAXID: 9606;                                                
SOURCE  18 EXPRESSION_SYSTEM: ESCHERICHIA COLI;                                 
SOURCE  19 EXPRESSION_SYSTEM_TAXID: 562;                                        
SOURCE  20 EXPRESSION_SYSTEM_STRAIN: BL21/DE3/PLYSS;                            
SOURCE  21 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                              
SOURCE  22 EXPRESSION_SYSTEM_PLASMID: PJUN(S)63                                 
KEYWDS    COILED-COIL, DNA-BINDING PROTEIN, HETERODIMER,                        
KEYWDS   2 TRANSCRIPTION/DNA COMPLEX                                            
EXPDTA    X-RAY DIFFRACTION                                                     
AUTHOR    J.N.M.GLOVER,S.C.HARRISON                                             
REVDAT   3   24-FEB-09 1FOS    1       VERSN                                    
REVDAT   2   01-APR-03 1FOS    1       JRNL                                     
REVDAT   1   10-JUL-95 1FOS    0                                                
JRNL        AUTH   J.N.GLOVER,S.C.HARRISON                                      
JRNL        TITL   CRYSTAL STRUCTURE OF THE HETERODIMERIC BZIP                  
JRNL        TITL 2 TRANSCRIPTION FACTOR C-FOS-C-JUN BOUND TO DNA.               
JRNL        REF    NATURE                        V. 373   257 1995              
JRNL        REFN                   ISSN 0028-0836                               
JRNL        PMID   7816143                                                      
JRNL        DOI    10.1038/373257A0                                             
REMARK   1                                                                      
REMARK   2                                                                      
REMARK   2 RESOLUTION.    3.05 ANGSTROMS.                                       
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   PROGRAM     : X-PLOR                                               
REMARK   3   AUTHORS     : BRUNGER                                              
REMARK   3                                                                      
REMARK   3  DATA USED IN REFINEMENT.                                            
REMARK   3   RESOLUTION RANGE HIGH (ANGSTROMS) : 3.05                           
REMARK   3   RESOLUTION RANGE LOW  (ANGSTROMS) : 10.00                          
REMARK   3   DATA CUTOFF            (SIGMA(F)) : 2.000                          
REMARK   3   DATA CUTOFF HIGH         (ABS(F)) : NULL                           
REMARK   3   DATA CUTOFF LOW          (ABS(F)) : NULL                           
REMARK   3   COMPLETENESS (WORKING+TEST)   (%) : NULL                           
REMARK   3   NUMBER OF REFLECTIONS             : NULL                           
REMARK   3                                                                      
REMARK   3  FIT TO DATA USED IN REFINEMENT.                                     
REMARK   3   CROSS-VALIDATION METHOD          : NULL                            
REMARK   3   FREE R VALUE TEST SET SELECTION  : NULL                            
REMARK   3   R VALUE            (WORKING SET) : 0.230                           
REMARK   3   FREE R VALUE                     : 0.321                           
REMARK   3   FREE R VALUE TEST SET SIZE   (%) : NULL                            
REMARK   3   FREE R VALUE TEST SET COUNT      : NULL                            
REMARK   3   ESTIMATED ERROR OF FREE R VALUE  : NULL                            
REMARK   3                                                                      
REMARK   3  FIT IN THE HIGHEST RESOLUTION BIN.                                  
REMARK   3   TOTAL NUMBER OF BINS USED           : NULL                         
REMARK   3   BIN RESOLUTION RANGE HIGH       (A) : NULL                         
REMARK   3   BIN RESOLUTION RANGE LOW        (A) : NULL                         
REMARK   3   BIN COMPLETENESS (WORKING+TEST) (%) : NULL                         
REMARK   3   REFLECTIONS IN BIN    (WORKING SET) : NULL                         
REMARK   3   BIN R VALUE           (WORKING SET) : NULL                         
REMARK   3   BIN FREE R VALUE                    : NULL                         
REMARK   3   BIN FREE R VALUE TEST SET SIZE  (%) : NULL                         
REMARK   3   BIN FREE R VALUE TEST SET COUNT     : NULL                         
REMARK   3   ESTIMATED ERROR OF BIN FREE R VALUE : NULL                         
REMARK   3                                                                      
REMARK   3  NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT.                    
REMARK   3   PROTEIN ATOMS            : 1856                                    
REMARK   3   NUCLEIC ACID ATOMS       : 1628                                    
REMARK   3   HETEROGEN ATOMS          : 0                                       
REMARK   3   SOLVENT ATOMS            : 0                                       
REMARK   3                                                                      
REMARK   3  B VALUES.                                                           
REMARK   3   FROM WILSON PLOT           (A**2) : NULL                           
REMARK   3   MEAN B VALUE      (OVERALL, A**2) : NULL                           
REMARK   3   OVERALL ANISOTROPIC B VALUE.                                       
REMARK   3    B11 (A**2) : NULL                                                 
REMARK   3    B22 (A**2) : NULL                                                 
REMARK   3    B33 (A**2) : NULL                                                 
REMARK   3    B12 (A**2) : NULL                                                 
REMARK   3    B13 (A**2) : NULL                                                 
REMARK   3    B23 (A**2) : NULL                                                 
REMARK   3                                                                      
REMARK   3  ESTIMATED COORDINATE ERROR.                                         
REMARK   3   ESD FROM LUZZATI PLOT        (A) : NULL                            
REMARK   3   ESD FROM SIGMAA              (A) : NULL                            
REMARK   3   LOW RESOLUTION CUTOFF        (A) : NULL                            
REMARK   3                                                                      
REMARK   3  CROSS-VALIDATED ESTIMATED COORDINATE ERROR.                         
REMARK   3   ESD FROM C-V LUZZATI PLOT    (A) : NULL                            
REMARK   3   ESD FROM C-V SIGMAA          (A) : NULL                            
REMARK   3                                                                      
REMARK   3  RMS DEVIATIONS FROM IDEAL VALUES.                                   
REMARK   3   BOND LENGTHS                 (A) : 0.010                           
REMARK   3   BOND ANGLES            (DEGREES) : 1.33                            
REMARK   3   DIHEDRAL ANGLES        (DEGREES) : NULL                            
REMARK   3   IMPROPER ANGLES        (DEGREES) : NULL                            
REMARK   3                                                                      
REMARK   3  ISOTROPIC THERMAL MODEL : NULL                                      
REMARK   3                                                                      
REMARK   3  ISOTROPIC THERMAL FACTOR RESTRAINTS.    RMS    SIGMA                
REMARK   3   MAIN-CHAIN BOND              (A**2) : NULL  ; NULL                 
REMARK   3   MAIN-CHAIN ANGLE             (A**2) : NULL  ; NULL                 
REMARK   3   SIDE-CHAIN BOND              (A**2) : NULL  ; NULL                 
REMARK   3   SIDE-CHAIN ANGLE             (A**2) : NULL  ; NULL                 
REMARK   3                                                                      
REMARK   3  NCS MODEL : NULL                                                    
REMARK   3                                                                      
REMARK   3  NCS RESTRAINTS.                         RMS   SIGMA/WEIGHT          
REMARK   3   GROUP  1  POSITIONAL            (A) : NULL  ; NULL                 
REMARK   3   GROUP  1  B-FACTOR           (A**2) : NULL  ; NULL                 
REMARK   3                                                                      
REMARK   3  PARAMETER FILE  1  : NULL                                           
REMARK   3  TOPOLOGY FILE  1   : NULL                                           
REMARK   3                                                                      
REMARK   3  OTHER REFINEMENT REMARKS: NULL                                      
REMARK   4                                                                      
REMARK   4 1FOS COMPLIES WITH FORMAT V. 3.15, 01-DEC-08                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY BNL.                                
REMARK 200                                                                      
REMARK 200 EXPERIMENTAL DETAILS                                                 
REMARK 200  EXPERIMENT TYPE                : X-RAY DIFFRACTION                  
REMARK 200  DATE OF DATA COLLECTION        : NULL                               
REMARK 200  TEMPERATURE           (KELVIN) : NULL                               
REMARK 200  PH                             : 6.70                               
REMARK 200  NUMBER OF CRYSTALS USED        : 1                                  
REMARK 200                                                                      
REMARK 200  SYNCHROTRON              (Y/N) : N                                  
REMARK 200  RADIATION SOURCE               : NULL                               
REMARK 200  BEAMLINE                       : NULL                               
REMARK 200  X-RAY GENERATOR MODEL          : NULL                               
REMARK 200  MONOCHROMATIC OR LAUE    (M/L) : M                                  
REMARK 200  WAVELENGTH OR RANGE        (A) : 1.54                               
REMARK 200  MONOCHROMATOR                  : NULL                               
REMARK 200  OPTICS                         : NULL                               
REMARK 200                                                                      
REMARK 200  DETECTOR TYPE                  : IMAGE PLATE                        
REMARK 200  DETECTOR MANUFACTURER          : MARRESEARCH                        
REMARK 200  INTENSITY-INTEGRATION SOFTWARE : XDS                                
REMARK 200  DATA SCALING SOFTWARE          : NULL                               
REMARK 200                                                                      
REMARK 200  NUMBER OF UNIQUE REFLECTIONS   : 14316                              
REMARK 200  RESOLUTION RANGE HIGH      (A) : NULL                               
REMARK 200  RESOLUTION RANGE LOW       (A) : NULL                               
REMARK 200  REJECTION CRITERIA  (SIGMA(I)) : 1.000                              
REMARK 200                                                                      
REMARK 200 OVERALL.                                                             
REMARK 200  COMPLETENESS FOR RANGE     (%) : 91.1                               
REMARK 200  DATA REDUNDANCY                : NULL                               
REMARK 200  R MERGE                    (I) : NULL                               
REMARK 200  R SYM                      (I) : NULL                               
REMARK 200  <I/SIGMA(I)> FOR THE DATA SET  : NULL                               
REMARK 200                                                                      
REMARK 200 IN THE HIGHEST RESOLUTION SHELL.                                     
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : NULL                     
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE LOW  (A) : NULL                     
REMARK 200  COMPLETENESS FOR SHELL     (%) : NULL                               
REMARK 200  DATA REDUNDANCY IN SHELL       : NULL                               
REMARK 200  R MERGE FOR SHELL          (I) : NULL                               
REMARK 200  R SYM FOR SHELL            (I) : NULL                               
REMARK 200  <I/SIGMA(I)> FOR SHELL         : NULL                               
REMARK 200                                                                      
REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH                              
REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: NULL                         
REMARK 200 SOFTWARE USED: NULL                                                  
REMARK 200 STARTING MODEL: NULL                                                 
REMARK 200                                                                      
REMARK 200 REMARK: NULL                                                         
REMARK 280                                                                      
REMARK 280 CRYSTAL                                                              
REMARK 280 SOLVENT CONTENT, VS   (%): 65.18                                     
REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 3.53                     
REMARK 280                                                                      
REMARK 280 CRYSTALLIZATION CONDITIONS: PH 6.70, VAPOR DIFFUSION, HANGING        
REMARK 280  DROP, TEMPERATURE 293.00K                                           
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY                                            
REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 21 21 2                        
REMARK 290                                                                      
REMARK 290      SYMOP   SYMMETRY                                                
REMARK 290     NNNMMM   OPERATOR                                                
REMARK 290       1555   X,Y,Z                                                   
REMARK 290       2555   -X,-Y,Z                                                 
REMARK 290       3555   -X+1/2,Y+1/2,-Z                                         
REMARK 290       4555   X+1/2,-Y+1/2,-Z                                         
REMARK 290                                                                      
REMARK 290     WHERE NNN -> OPERATOR NUMBER                                     
REMARK 290           MMM -> TRANSLATION VECTOR                                  
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS                            
REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM             
REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY                
REMARK 290 RELATED MOLECULES.                                                   
REMARK 290   SMTRY1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY1   2 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   2  0.000000 -1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   2  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY1   3 -1.000000  0.000000  0.000000      120.55000            
REMARK 290   SMTRY2   3  0.000000  1.000000  0.000000       24.34500            
REMARK 290   SMTRY3   3  0.000000  0.000000 -1.000000        0.00000            
REMARK 290   SMTRY1   4  1.000000  0.000000  0.000000      120.55000            
REMARK 290   SMTRY2   4  0.000000 -1.000000  0.000000       24.34500            
REMARK 290   SMTRY3   4  0.000000  0.000000 -1.000000        0.00000            
REMARK 290                                                                      
REMARK 290 REMARK: NULL                                                         
REMARK 300                                                                      
REMARK 300 BIOMOLECULE: 1, 2                                                    
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM                
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN                  
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON               
REMARK 300 BURIED SURFACE AREA.                                                 
REMARK 350                                                                      
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN           
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE                
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS          
REMARK 350 GIVEN BELOW.  BOTH NON-CRYSTALLOGRAPHIC AND                          
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.                               
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 1                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TETRAMERIC                        
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B, E, F                            
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 2                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TETRAMERIC                        
REMARK 350 APPLY THE FOLLOWING TO CHAINS: C, D, G, H                            
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 465                                                                      
REMARK 465 MISSING RESIDUES                                                     
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE                       
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)                
REMARK 465                                                                      
REMARK 465   M RES C SSSEQI                                                     
REMARK 465     ALA E   199                                                      
REMARK 465     HIS E   200                                                      
REMARK 465     LYS F   263                                                      
REMARK 465     ALA F   264                                                      
REMARK 465     GLU F   265                                                      
REMARK 465     ASN F   323                                                      
REMARK 465     HIS F   324                                                      
REMARK 465     LYS G   139                                                      
REMARK 465     ALA G   199                                                      
REMARK 465     HIS G   200                                                      
REMARK 465     LYS H   263                                                      
REMARK 465     ALA H   264                                                      
REMARK 465     ASN H   323                                                      
REMARK 465     HIS H   324                                                      
REMARK 470                                                                      
REMARK 470 MISSING ATOM                                                         
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS(M=MODEL NUMBER;            
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;          
REMARK 470 I=INSERTION CODE):                                                   
REMARK 470   M RES CSSEQI  ATOMS                                                
REMARK 470     ARG E 144    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG E 157    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG F 266    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG F 270    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU F 312    CG   CD   OE1  OE2                                  
REMARK 470     GLN F 316    CG   CD   OE1  NE2                                  
REMARK 470     GLN F 319    CG   CD   OE1  NE2                                  
REMARK 470     ARG G 140    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG G 141    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ILE G 142    CG1  CG2  CD1                                       
REMARK 470     GLU H 265    CG   CD   OE1  OE2                                  
REMARK 470     ARG H 270    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     SER H 276    OG                                                  
REMARK 470     LYS H 294    CG   CD   CE   NZ                                   
REMARK 470     GLU H 312    CG   CD   OE1  OE2                                  
REMARK 470     GLN H 316    CG   CD   OE1  NE2                                  
REMARK 470     GLN H 319    CG   CD   OE1  NE2                                  
REMARK 470     LYS H 320    CG   CD   CE   NZ                                   
REMARK 475                                                                      
REMARK 475 ZERO OCCUPANCY RESIDUES                                              
REMARK 475 THE FOLLOWING RESIDUES WERE MODELED WITH ZERO OCCUPANCY.             
REMARK 475 THE LOCATION AND PROPERTIES OF THESE RESIDUES MAY NOT                
REMARK 475 BE RELIABLE. (M=MODEL NUMBER; RES=RESIDUE NAME;                      
REMARK 475 C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE)          
REMARK 475   M RES C SSEQI                                                      
REMARK 475     GLU H  265                                                       
REMARK 480                                                                      
REMARK 480 ZERO OCCUPANCY ATOM                                                  
REMARK 480 THE FOLLOWING RESIDUES HAVE ATOMS MODELED WITH ZERO                  
REMARK 480 OCCUPANCY. THE LOCATION AND PROPERTIES OF THESE ATOMS                
REMARK 480 MAY NOT BE RELIABLE. (M=MODEL NUMBER; RES=RESIDUE NAME;              
REMARK 480 C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE):         
REMARK 480   M RES C SSEQI ATOMS                                                
REMARK 480     LYS F  277   CG    CD    CE    NZ                                
REMARK 480     LYS F  280   CG    CD    CE    NZ                                
REMARK 480     ARG F  281   CG    CD    NE    CZ    NH1   NH2                   
REMARK 480     GLU F  291   CG    CD    OE1   OE2                               
REMARK 480     LYS F  294   CG    CD    CE    NZ                                
REMARK 480     SER F  301   OG                                                  
REMARK 480     GLU G  145   CG    CD    OE1   OE2                               
REMARK 480     LYS G  148   CG    CD    CE    NZ                                
REMARK 480     ASN G  156   CG    OD1   ND2                                     
REMARK 480     GLN G  171   CG    CD    OE1   NE2                               
REMARK 480     LYS G  192   CG    CD    CE    NZ                                
REMARK 480     LYS H  280   CG    CD    CE    NZ                                
REMARK 480     SER H  301   OG                                                  
REMARK 480     MET H  322   O     CG    SD    CE                                
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: COVALENT BOND LENGTHS                                      
REMARK 500                                                                      
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES              
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE               
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                 
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT: (10X,I3,1X,2(A3,1X,A1,I4,A1,1X,A4,3X),1X,F6.3)               
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999                        
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996                     
REMARK 500                                                                      
REMARK 500  M RES CSSEQI ATM1   RES CSSEQI ATM2   DEVIATION                     
REMARK 500     DT D  24   N1     DT D  24   C2      0.049                       
REMARK 500     DT D  24   C5     DT D  24   C7      0.042                       
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES                                       
REMARK 500                                                                      
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES              
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE               
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                 
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)              
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999                        
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996                     
REMARK 500                                                                      
REMARK 500  M RES CSSEQI ATM1   ATM2   ATM3                                     
REMARK 500     DA A   1   C6  -  N1  -  C2  ANGL. DEV. =   4.2 DEGREES          
REMARK 500     DA A   1   N1  -  C2  -  N3  ANGL. DEV. =  -4.1 DEGREES          
REMARK 500     DA A   2   C4' -  C3' -  C2' ANGL. DEV. =   5.8 DEGREES          
REMARK 500     DA A   2   O4' -  C1' -  C2' ANGL. DEV. =   3.5 DEGREES          
REMARK 500     DA A   2   C6  -  N1  -  C2  ANGL. DEV. =   4.7 DEGREES          
REMARK 500     DA A   2   N1  -  C2  -  N3  ANGL. DEV. =  -4.3 DEGREES          
REMARK 500     DT A   3   C2  -  N3  -  C4  ANGL. DEV. =  -4.3 DEGREES          
REMARK 500     DG A   4   C5  -  C6  -  N1  ANGL. DEV. =   3.2 DEGREES          
REMARK 500     DG A   5   C4' -  C3' -  C2' ANGL. DEV. =   5.5 DEGREES          
REMARK 500     DG A   5   C5  -  C6  -  N1  ANGL. DEV. =   3.2 DEGREES          
REMARK 500     DA A   6   C4' -  C3' -  C2' ANGL. DEV. =   6.0 DEGREES          
REMARK 500     DA A   6   C6  -  N1  -  C2  ANGL. DEV. =   4.6 DEGREES          
REMARK 500     DA A   6   N1  -  C2  -  N3  ANGL. DEV. =  -4.5 DEGREES          
REMARK 500     DT A   7   C4' -  C3' -  C2' ANGL. DEV. =   5.5 DEGREES          
REMARK 500     DT A   7   C2  -  N3  -  C4  ANGL. DEV. =  -4.5 DEGREES          
REMARK 500     DG A   8   O4' -  C1' -  C2' ANGL. DEV. =   3.2 DEGREES          
REMARK 500     DG A   8   C5  -  C6  -  N1  ANGL. DEV. =   3.3 DEGREES          
REMARK 500     DA A   9   C6  -  N1  -  C2  ANGL. DEV. =   4.4 DEGREES          
REMARK 500     DA A   9   N1  -  C2  -  N3  ANGL. DEV. =  -4.2 DEGREES          
REMARK 500     DT A  11   C4' -  C3' -  C2' ANGL. DEV. =   6.0 DEGREES          
REMARK 500     DT A  11   N1  -  C2  -  N3  ANGL. DEV. =   3.6 DEGREES          
REMARK 500     DT A  11   C2  -  N3  -  C4  ANGL. DEV. =  -5.0 DEGREES          
REMARK 500     DC A  12   C4' -  C3' -  C2' ANGL. DEV. =   6.0 DEGREES          
REMARK 500     DA A  13   C6  -  N1  -  C2  ANGL. DEV. =   4.3 DEGREES          
REMARK 500     DA A  13   N1  -  C2  -  N3  ANGL. DEV. =  -4.2 DEGREES          
REMARK 500     DT A  14   C2  -  N3  -  C4  ANGL. DEV. =  -4.7 DEGREES          
REMARK 500     DA A  15   C6  -  N1  -  C2  ANGL. DEV. =   4.3 DEGREES          
REMARK 500     DA A  15   N1  -  C2  -  N3  ANGL. DEV. =  -4.5 DEGREES          
REMARK 500     DA A  15   C3' -  O3' -  P   ANGL. DEV. =   8.0 DEGREES          
REMARK 500     DA A  18   C4' -  C3' -  C2' ANGL. DEV. =   5.7 DEGREES          
REMARK 500     DA A  18   O4' -  C1' -  C2' ANGL. DEV. =   3.3 DEGREES          
REMARK 500     DA A  18   C6  -  N1  -  C2  ANGL. DEV. =   4.3 DEGREES          
REMARK 500     DA A  18   N1  -  C2  -  N3  ANGL. DEV. =  -4.5 DEGREES          
REMARK 500     DG A  17   C3' -  O3' -  P   ANGL. DEV. =   7.6 DEGREES          
REMARK 500     DG A  19   O4' -  C1' -  N9  ANGL. DEV. =   1.8 DEGREES          
REMARK 500     DG A  19   C5  -  C6  -  N1  ANGL. DEV. =   3.3 DEGREES          
REMARK 500     DA A  20   C6  -  N1  -  C2  ANGL. DEV. =   4.1 DEGREES          
REMARK 500     DA A  20   N1  -  C2  -  N3  ANGL. DEV. =  -4.2 DEGREES          
REMARK 500     DT B  21   C4' -  C3' -  C2' ANGL. DEV. =   5.5 DEGREES          
REMARK 500     DT B  21   C2  -  N3  -  C4  ANGL. DEV. =  -4.0 DEGREES          
REMARK 500     DT B  22   O4' -  C1' -  N1  ANGL. DEV. =   2.6 DEGREES          
REMARK 500     DT B  22   N1  -  C2  -  N3  ANGL. DEV. =   3.7 DEGREES          
REMARK 500     DT B  22   C2  -  N3  -  C4  ANGL. DEV. =  -4.4 DEGREES          
REMARK 500     DT B  24   C2  -  N3  -  C4  ANGL. DEV. =  -4.3 DEGREES          
REMARK 500     DT B  24   N3  -  C4  -  C5  ANGL. DEV. =   3.7 DEGREES          
REMARK 500     DC B  26   O4' -  C1' -  N1  ANGL. DEV. =   2.0 DEGREES          
REMARK 500     DT B  27   C4' -  C3' -  C2' ANGL. DEV. =   6.2 DEGREES          
REMARK 500     DT B  27   C2  -  N3  -  C4  ANGL. DEV. =  -4.9 DEGREES          
REMARK 500     DT B  27   N3  -  C4  -  C5  ANGL. DEV. =   3.7 DEGREES          
REMARK 500     DA B  28   C6  -  N1  -  C2  ANGL. DEV. =   4.6 DEGREES          
REMARK 500                                                                      
REMARK 500 THIS ENTRY HAS     143 ANGLE DEVIATIONS.                             
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: TORSION ANGLES                                             
REMARK 500                                                                      
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:            
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)                    
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-           
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400            
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        PSI       PHI                                   
REMARK 500    ARG E 141      -35.31    -36.63                                   
REMARK 500    ILE E 142      -70.24    -74.02                                   
REMARK 500    LEU G 197        0.71    -69.86                                   
REMARK 500    ARG H 266       95.24    -68.69                                   
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 999                                                                      
REMARK 999 SEQUENCE                                                             
REMARK 999                                                                      
REMARK 999 FOS SEQUENCE EXPRESSED CORRESPONDS TO RESIDUES 139 - 200             
REMARK 999 OF HUMAN P55-C-FOS PROTO-ONCOGENE PROTEIN.                           
REMARK 999 JUN SEQUENCE EXPRESSED CORRESPONDS TO RESIDUES 263 - 324             
REMARK 999 OF HUMAN TRANSCRIPTION FACTOR AP-1 (C-JUN PROTO-ONCOGENE).           
DBREF  1FOS E  139   200  UNP    P01100   FOS_HUMAN      139    200             
DBREF  1FOS G  139   200  UNP    P01100   FOS_HUMAN      139    200             
DBREF  1FOS F  263   324  GB     386839   AAA59197       254    315             
DBREF  1FOS H  263   324  GB     386839   AAA59197       254    315             
DBREF  1FOS A    1    20  PDB    1FOS     1FOS             1     20             
DBREF  1FOS B   21    40  PDB    1FOS     1FOS            21     40             
DBREF  1FOS C    1    20  PDB    1FOS     1FOS             1     20             
DBREF  1FOS D   21    40  PDB    1FOS     1FOS            21     40             
SEQADV 1FOS SER E  154  UNP  P01100    CYS   154 ENGINEERED                     
SEQADV 1FOS SER G  154  UNP  P01100    CYS   154 ENGINEERED                     
SEQADV 1FOS SER F  278  GB   386839    CYS   269 ENGINEERED                     
SEQADV 1FOS SER H  278  GB   386839    CYS   269 ENGINEERED                     
SEQRES   1 A   20   DA  DA  DT  DG  DG  DA  DT  DG  DA  DG  DT  DC  DA          
SEQRES   2 A   20   DT  DA  DG  DG  DA  DG  DA                                  
SEQRES   1 B   20   DT  DT  DC  DT  DC  DC  DT  DA  DT  DG  DA  DC  DT          
SEQRES   2 B   20   DC  DA  DT  DC  DC  DA  DT                                  
SEQRES   1 C   20   DA  DA  DT  DG  DG  DA  DT  DG  DA  DG  DT  DC  DA          
SEQRES   2 C   20   DT  DA  DG  DG  DA  DG  DA                                  
SEQRES   1 D   20   DT  DT  DC  DT  DC  DC  DT  DA  DT  DG  DA  DC  DT          
SEQRES   2 D   20   DC  DA  DT  DC  DC  DA  DT                                  
SEQRES   1 E   62  LYS ARG ARG ILE ARG ARG GLU ARG ASN LYS MET ALA ALA          
SEQRES   2 E   62  ALA LYS SER ARG ASN ARG ARG ARG GLU LEU THR ASP THR          
SEQRES   3 E   62  LEU GLN ALA GLU THR ASP GLN LEU GLU ASP GLU LYS SER          
SEQRES   4 E   62  ALA LEU GLN THR GLU ILE ALA ASN LEU LEU LYS GLU LYS          
SEQRES   5 E   62  GLU LYS LEU GLU PHE ILE LEU ALA ALA HIS                      
SEQRES   1 F   62  LYS ALA GLU ARG LYS ARG MET ARG ASN ARG ILE ALA ALA          
SEQRES   2 F   62  SER LYS SER ARG LYS ARG LYS LEU GLU ARG ILE ALA ARG          
SEQRES   3 F   62  LEU GLU GLU LYS VAL LYS THR LEU LYS ALA GLN ASN SER          
SEQRES   4 F   62  GLU LEU ALA SER THR ALA ASN MET LEU ARG GLU GLN VAL          
SEQRES   5 F   62  ALA GLN LEU LYS GLN LYS VAL MET ASN HIS                      
SEQRES   1 G   62  LYS ARG ARG ILE ARG ARG GLU ARG ASN LYS MET ALA ALA          
SEQRES   2 G   62  ALA LYS SER ARG ASN ARG ARG ARG GLU LEU THR ASP THR          
SEQRES   3 G   62  LEU GLN ALA GLU THR ASP GLN LEU GLU ASP GLU LYS SER          
SEQRES   4 G   62  ALA LEU GLN THR GLU ILE ALA ASN LEU LEU LYS GLU LYS          
SEQRES   5 G   62  GLU LYS LEU GLU PHE ILE LEU ALA ALA HIS                      
SEQRES   1 H   62  LYS ALA GLU ARG LYS ARG MET ARG ASN ARG ILE ALA ALA          
SEQRES   2 H   62  SER LYS SER ARG LYS ARG LYS LEU GLU ARG ILE ALA ARG          
SEQRES   3 H   62  LEU GLU GLU LYS VAL LYS THR LEU LYS ALA GLN ASN SER          
SEQRES   4 H   62  GLU LEU ALA SER THR ALA ASN MET LEU ARG GLU GLN VAL          
SEQRES   5 H   62  ALA GLN LEU LYS GLN LYS VAL MET ASN HIS                      
HELIX    1   1 LYS E  139  LEU E  197  1                                  59    
HELIX    2   2 ARG F  266  MET F  322  1                                  57    
HELIX    3   3 ARG G  140  ALA G  198  1                                  59    
HELIX    4   4 ARG H  266  MET H  322  1                                  57    
CRYST1  241.100   48.690   66.000  90.00  90.00  90.00 P 21 21 2     8          
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      0.004148  0.000000  0.000000        0.00000                         
SCALE2      0.000000  0.020538  0.000000        0.00000                         
SCALE3      0.000000  0.000000  0.015152        0.00000                         
(ATOM LINES ARE NOT SHOWN.)
END                                                                             
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