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Database: PDB
Entry: 1GPQ
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Original site: 1GPQ 
HEADER    HYDROLASE/INHIBITOR                     08-NOV-01   1GPQ              
TITLE     STRUCTURE OF IVY COMPLEXED WITH ITS TARGET, HEWL                      
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: INHIBITOR OF VERTEBRATE LYSOZYME;                          
COMPND   3 CHAIN: A, B;                                                         
COMPND   4 SYNONYM: IVY;                                                        
COMPND   5 ENGINEERED: YES;                                                     
COMPND   6 OTHER_DETAILS: COMPLEXED WITH HEWL IN CRYSTAL;                       
COMPND   7 MOL_ID: 2;                                                           
COMPND   8 MOLECULE: LYSOZYME C;                                                
COMPND   9 CHAIN: C, D;                                                         
COMPND  10 EC: 3.2.1.17;                                                        
COMPND  11 OTHER_DETAILS: COMPLEXED WITH IVY IN CRYSTAL                         
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;                               
SOURCE   3 ORGANISM_TAXID: 83333;                                               
SOURCE   4 STRAIN: K12;                                                         
SOURCE   5 EXPRESSION_SYSTEM: ESCHERICHIA COLI;                                 
SOURCE   6 EXPRESSION_SYSTEM_TAXID: 562;                                        
SOURCE   7 MOL_ID: 2;                                                           
SOURCE   8 ORGANISM_SCIENTIFIC: GALLUS GALLUS;                                  
SOURCE   9 ORGANISM_COMMON: CHICKEN;                                            
SOURCE  10 ORGANISM_TAXID: 9031                                                 
KEYWDS    HYDROLASE-INHIBITOR COMPLEX, LYSOZYME/INHIBITOR COMPLEX, TYPE-C       
KEYWDS   2 LYSOZYME INHIBITOR, HYDROLASE, GLYCOSIDASE, BACTERIAL TARGETS AT     
KEYWDS   3 IGS-CNRS, FRANCE, BIGS, STRUCTURAL GENOMICS                          
EXPDTA    X-RAY DIFFRACTION                                                     
AUTHOR    C.ABERGEL,V.MONCHOIS,J.-M.CLAVERIE                                    
REVDAT   3   29-JUN-11 1GPQ    1       VERSN                                    
REVDAT   2   24-FEB-09 1GPQ    1       VERSN                                    
REVDAT   1   11-MAR-03 1GPQ    0                                                
JRNL        AUTH   C.ABERGEL,V.MONCHOIS,D.BYRNE,S.CHENIVESSE,F.LEMBO,           
JRNL        AUTH 2 J.LAZZARONI,J.CLAVERIE                                       
JRNL        TITL   STRUCTURE AND EVOLUTION OF THE IVY PROTEIN FAMILY,           
JRNL        TITL 2 UNEXPECTED LYSOZYME INHIBITORS IN GRAM-NEGATIVE BACTERIA.    
JRNL        REF    PROC.NATL.ACAD.SCI.USA        V. 104  6394 2007              
JRNL        REFN                   ISSN 0027-8424                               
JRNL        PMID   17405861                                                     
JRNL        DOI    10.1073/PNAS.0611019104                                      
REMARK   1                                                                      
REMARK   1 REFERENCE 1                                                          
REMARK   1  AUTH   V.MONCHOIS,C.ABERGEL,J.STURGIS,S.JEUDY,J.-M.CLAVERIE         
REMARK   1  TITL   ESCHERICHIA COLI YKFE "ORFAN" GENE ENCODES A POTENT          
REMARK   1  TITL 2 INHIBITOR OF C-TYPE LYSOZYME                                 
REMARK   1  REF    J.BIOL.CHEM.                  V. 276 18437 2001              
REMARK   1  REFN                   ISSN 0021-9258                               
REMARK   1  PMID   11278658                                                     
REMARK   1  DOI    10.1074/JBC.M010297200                                       
REMARK   1 REFERENCE 2                                                          
REMARK   1  AUTH   C.ABERGEL,V.MONCHOIS,S.CHENIVESSE,S.JEUDY,J.-M.CLAVERIE      
REMARK   1  TITL   CRYSTALLIZATION AND PRELIMINARY CRYSTALLOGRAPHIC STUDY OF    
REMARK   1  TITL 2 B0220, AN "ORFAN" PROTEIN OF UNKNOWN FUNCTION FROM           
REMARK   1  TITL 3 ESCHERICHIA COLI                                             
REMARK   1  REF    ACTA CRYSTALLOGR.,SECT.D      V.  56  1694 2000              
REMARK   1  REFN                   ISSN 0907-4449                               
REMARK   1  PMID   11092949                                                     
REMARK   1  DOI    10.1107/S0907444900015316                                    
REMARK   2                                                                      
REMARK   2 RESOLUTION.     1.6 ANGSTROMS.                                       
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   PROGRAM     : CNS 1.0                                              
REMARK   3   AUTHORS     : BRUNGER,ADAMS,CLORE,DELANO,GROS,GROSSE-              
REMARK   3               : KUNSTLEVE,JIANG,KUSZEWSKI,NILGES,PANNU,              
REMARK   3               : READ,RICE,SIMONSON,WARREN                            
REMARK   3                                                                      
REMARK   3  REFINEMENT TARGET : NULL                                            
REMARK   3                                                                      
REMARK   3  DATA USED IN REFINEMENT.                                            
REMARK   3   RESOLUTION RANGE HIGH (ANGSTROMS) : 1.6                            
REMARK   3   RESOLUTION RANGE LOW  (ANGSTROMS) : 20                             
REMARK   3   DATA CUTOFF            (SIGMA(F)) : 0.0                            
REMARK   3   DATA CUTOFF HIGH         (ABS(F)) : 688920.93                      
REMARK   3   DATA CUTOFF LOW          (ABS(F)) : NULL                           
REMARK   3   COMPLETENESS (WORKING+TEST)   (%) : 99                             
REMARK   3   NUMBER OF REFLECTIONS             : 58780                          
REMARK   3                                                                      
REMARK   3  FIT TO DATA USED IN REFINEMENT.                                     
REMARK   3   CROSS-VALIDATION METHOD          : THROUGHOUT                      
REMARK   3   FREE R VALUE TEST SET SELECTION  : RANDOM                          
REMARK   3   R VALUE            (WORKING SET) : 0.181                           
REMARK   3   FREE R VALUE                     : 0.212                           
REMARK   3   FREE R VALUE TEST SET SIZE   (%) : 10.0                            
REMARK   3   FREE R VALUE TEST SET COUNT      : 5962                            
REMARK   3   ESTIMATED ERROR OF FREE R VALUE  : 0.003                           
REMARK   3                                                                      
REMARK   3  FIT IN THE HIGHEST RESOLUTION BIN.                                  
REMARK   3   TOTAL NUMBER OF BINS USED           : 6                            
REMARK   3   BIN RESOLUTION RANGE HIGH       (A) : 1.6                          
REMARK   3   BIN RESOLUTION RANGE LOW        (A) : 1.7                          
REMARK   3   BIN COMPLETENESS (WORKING+TEST) (%) : 99.9                         
REMARK   3   REFLECTIONS IN BIN    (WORKING SET) : 8832                         
REMARK   3   BIN R VALUE           (WORKING SET) : 0.186                        
REMARK   3   BIN FREE R VALUE                    : 0.213                        
REMARK   3   BIN FREE R VALUE TEST SET SIZE  (%) : 10                           
REMARK   3   BIN FREE R VALUE TEST SET COUNT     : 991                          
REMARK   3   ESTIMATED ERROR OF BIN FREE R VALUE : 0.007                        
REMARK   3                                                                      
REMARK   3  NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT.                    
REMARK   3   PROTEIN ATOMS            : 3923                                    
REMARK   3   NUCLEIC ACID ATOMS       : 0                                       
REMARK   3   HETEROGEN ATOMS          : 0                                       
REMARK   3   SOLVENT ATOMS            : 635                                     
REMARK   3                                                                      
REMARK   3  B VALUES.                                                           
REMARK   3   FROM WILSON PLOT           (A**2) : 18.1                           
REMARK   3   MEAN B VALUE      (OVERALL, A**2) : 19.4                           
REMARK   3   OVERALL ANISOTROPIC B VALUE.                                       
REMARK   3    B11 (A**2) : -1.66                                                
REMARK   3    B22 (A**2) : 2.36                                                 
REMARK   3    B33 (A**2) : -0.69                                                
REMARK   3    B12 (A**2) : 0.00                                                 
REMARK   3    B13 (A**2) : -1.93                                                
REMARK   3    B23 (A**2) : 0.00                                                 
REMARK   3                                                                      
REMARK   3  ESTIMATED COORDINATE ERROR.                                         
REMARK   3   ESD FROM LUZZATI PLOT        (A) : 0.16                            
REMARK   3   ESD FROM SIGMAA              (A) : 0.05                            
REMARK   3   LOW RESOLUTION CUTOFF        (A) : 5.00                            
REMARK   3                                                                      
REMARK   3  CROSS-VALIDATED ESTIMATED COORDINATE ERROR.                         
REMARK   3   ESD FROM C-V LUZZATI PLOT    (A) : 0.19                            
REMARK   3   ESD FROM C-V SIGMAA          (A) : 0.06                            
REMARK   3                                                                      
REMARK   3  RMS DEVIATIONS FROM IDEAL VALUES.                                   
REMARK   3   BOND LENGTHS                 (A) : 0.009                           
REMARK   3   BOND ANGLES            (DEGREES) : 1.6                             
REMARK   3   DIHEDRAL ANGLES        (DEGREES) : 24.0                            
REMARK   3   IMPROPER ANGLES        (DEGREES) : 0.97                            
REMARK   3                                                                      
REMARK   3  ISOTROPIC THERMAL MODEL : RESTRAINED                                
REMARK   3                                                                      
REMARK   3  ISOTROPIC THERMAL FACTOR RESTRAINTS.    RMS    SIGMA                
REMARK   3   MAIN-CHAIN BOND              (A**2) : 1.34  ; 1.50                 
REMARK   3   MAIN-CHAIN ANGLE             (A**2) : 2.11  ; 2.00                 
REMARK   3   SIDE-CHAIN BOND              (A**2) : 2.05  ; 2.00                 
REMARK   3   SIDE-CHAIN ANGLE             (A**2) : 3.04  ; 2.50                 
REMARK   3                                                                      
REMARK   3  BULK SOLVENT MODELING.                                              
REMARK   3   METHOD USED : FLAT MODEL                                           
REMARK   3   KSOL        : 0.38                                                 
REMARK   3   BSOL        : 48.18                                                
REMARK   3                                                                      
REMARK   3  NCS MODEL : NULL                                                    
REMARK   3                                                                      
REMARK   3  NCS RESTRAINTS.                         RMS   SIGMA/WEIGHT          
REMARK   3   GROUP  1  POSITIONAL            (A) : NULL  ; NULL                 
REMARK   3   GROUP  1  B-FACTOR           (A**2) : NULL  ; NULL                 
REMARK   3                                                                      
REMARK   3  PARAMETER FILE  1  : PROTEIN_REP.PARAM                              
REMARK   3  PARAMETER FILE  2  : WATER_REP.PARAM                                
REMARK   3  PARAMETER FILE  3  : NULL                                           
REMARK   3  TOPOLOGY FILE  1   : PROTEIN.TOP                                    
REMARK   3  TOPOLOGY FILE  2   : WATER.TOP                                      
REMARK   3  TOPOLOGY FILE  3   : NULL                                           
REMARK   3                                                                      
REMARK   3  OTHER REFINEMENT REMARKS: NULL                                      
REMARK   4                                                                      
REMARK   4 1GPQ COMPLIES WITH FORMAT V. 3.20, 01-DEC-08                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBE ON 08-NOV-01.                  
REMARK 100 THE PDBE ID CODE IS EBI-8683.                                        
REMARK 200                                                                      
REMARK 200 EXPERIMENTAL DETAILS                                                 
REMARK 200  EXPERIMENT TYPE                : X-RAY DIFFRACTION                  
REMARK 200  DATE OF DATA COLLECTION        : 15-AUG-00                          
REMARK 200  TEMPERATURE           (KELVIN) : 100.0                              
REMARK 200  PH                             : 9.00                               
REMARK 200  NUMBER OF CRYSTALS USED        : NULL                               
REMARK 200                                                                      
REMARK 200  SYNCHROTRON              (Y/N) : Y                                  
REMARK 200  RADIATION SOURCE               : ESRF                               
REMARK 200  BEAMLINE                       : BM30A                              
REMARK 200  X-RAY GENERATOR MODEL          : NULL                               
REMARK 200  MONOCHROMATIC OR LAUE    (M/L) : M                                  
REMARK 200  WAVELENGTH OR RANGE        (A) : 0.9798                             
REMARK 200  MONOCHROMATOR                  : NULL                               
REMARK 200  OPTICS                         : NULL                               
REMARK 200                                                                      
REMARK 200  DETECTOR TYPE                  : NULL                               
REMARK 200  DETECTOR MANUFACTURER          : NULL                               
REMARK 200  INTENSITY-INTEGRATION SOFTWARE : DENZO                              
REMARK 200  DATA SCALING SOFTWARE          : CCP4 (SCALA)                       
REMARK 200                                                                      
REMARK 200  NUMBER OF UNIQUE REFLECTIONS   : 58982                              
REMARK 200  RESOLUTION RANGE HIGH      (A) : 1.600                              
REMARK 200  RESOLUTION RANGE LOW       (A) : 25.000                             
REMARK 200  REJECTION CRITERIA  (SIGMA(I)) : NULL                               
REMARK 200                                                                      
REMARK 200 OVERALL.                                                             
REMARK 200  COMPLETENESS FOR RANGE     (%) : 99.0                               
REMARK 200  DATA REDUNDANCY                : 3.400                              
REMARK 200  R MERGE                    (I) : 0.04400                            
REMARK 200  R SYM                      (I) : NULL                               
REMARK 200  <I/SIGMA(I)> FOR THE DATA SET  : 6.7000                             
REMARK 200                                                                      
REMARK 200 IN THE HIGHEST RESOLUTION SHELL.                                     
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 1.60                     
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE LOW  (A) : 1.65                     
REMARK 200  COMPLETENESS FOR SHELL     (%) : 99.0                               
REMARK 200  DATA REDUNDANCY IN SHELL       : 3.30                               
REMARK 200  R MERGE FOR SHELL          (I) : 0.13100                            
REMARK 200  R SYM FOR SHELL            (I) : NULL                               
REMARK 200  <I/SIGMA(I)> FOR SHELL         : 4.100                              
REMARK 200                                                                      
REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH                              
REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT        
REMARK 200 SOFTWARE USED: SOLVE, AMORE                                          
REMARK 200 STARTING MODEL: PDB ENTRY 1HEL                                       
REMARK 200                                                                      
REMARK 200 REMARK: UNCOMPLEXED, AND UNREFINED MAD IVY STRUCTURE WAS ALSO        
REMARK 200  USED FOR MOLECULAR REPLACEMENT                                      
REMARK 280                                                                      
REMARK 280 CRYSTAL                                                              
REMARK 280 SOLVENT CONTENT, VS   (%): 38                                        
REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 1.98                     
REMARK 280                                                                      
REMARK 280 CRYSTALLIZATION CONDITIONS: 15% PEG 4000, 5% GLYCEROL,               
REMARK 280  CHES BUFFER 0.1M PH 9.0, PROTEIN CONCENTRATION: 5MG.ML-1            
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY                                            
REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 1 21 1                         
REMARK 290                                                                      
REMARK 290      SYMOP   SYMMETRY                                                
REMARK 290     NNNMMM   OPERATOR                                                
REMARK 290       1555   X,Y,Z                                                   
REMARK 290       2555   -X,Y+1/2,-Z                                             
REMARK 290                                                                      
REMARK 290     WHERE NNN -> OPERATOR NUMBER                                     
REMARK 290           MMM -> TRANSLATION VECTOR                                  
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS                            
REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM             
REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY                
REMARK 290 RELATED MOLECULES.                                                   
REMARK 290   SMTRY1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY1   2 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   2  0.000000  1.000000  0.000000       29.78000            
REMARK 290   SMTRY3   2  0.000000  0.000000 -1.000000        0.00000            
REMARK 290                                                                      
REMARK 290 REMARK: NULL                                                         
REMARK 300                                                                      
REMARK 300 BIOMOLECULE: 1                                                       
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM                
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN                  
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON               
REMARK 300 BURIED SURFACE AREA.                                                 
REMARK 350                                                                      
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN           
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE                
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS          
REMARK 350 GIVEN BELOW.  BOTH NON-CRYSTALLOGRAPHIC AND                          
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.                               
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 1                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TETRAMERIC                        
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TETRAMERIC                 
REMARK 350 SOFTWARE USED: PISA                                                  
REMARK 350 TOTAL BURIED SURFACE AREA: 5510 ANGSTROM**2                          
REMARK 350 SURFACE AREA OF THE COMPLEX: 21990 ANGSTROM**2                       
REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -15.3 KCAL/MOL                        
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B, C, D                            
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 465                                                                      
REMARK 465 MISSING RESIDUES                                                     
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE                       
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)                
REMARK 465                                                                      
REMARK 465   M RES C SSSEQI                                                     
REMARK 465     GLN A     1                                                      
REMARK 465     ARG A   129                                                      
REMARK 465     HIS A   130                                                      
REMARK 465     HIS A   131                                                      
REMARK 465     HIS A   132                                                      
REMARK 465     HIS A   133                                                      
REMARK 465     HIS A   134                                                      
REMARK 465     HIS A   135                                                      
REMARK 465     GLN B     1                                                      
REMARK 465     HIS B   130                                                      
REMARK 465     HIS B   131                                                      
REMARK 465     HIS B   132                                                      
REMARK 465     HIS B   133                                                      
REMARK 465     HIS B   134                                                      
REMARK 465     HIS B   135                                                      
REMARK 465     ARG C   128                                                      
REMARK 465     LEU C   129                                                      
REMARK 465     LEU D   129                                                      
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES                                       
REMARK 500                                                                      
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES              
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE               
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                 
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)              
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999                        
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996                     
REMARK 500                                                                      
REMARK 500  M RES CSSEQI ATM1   ATM2   ATM3                                     
REMARK 500    CYS B  57   CA  -  CB  -  SG  ANGL. DEV. =  25.1 DEGREES          
REMARK 500    CYS B  57   CB  -  CA  -  C   ANGL. DEV. = -13.8 DEGREES          
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: TORSION ANGLES                                             
REMARK 500                                                                      
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:            
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)                    
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-           
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400            
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        PSI       PHI                                   
REMARK 500    ASP A  61       47.24   -150.87                                   
REMARK 500    ASN A  76      -22.51     78.22                                   
REMARK 500    ILE A 105      -76.18   -114.51                                   
REMARK 500    ASP B   3      -57.14    173.51                                   
REMARK 500    ASP B  61       43.73   -149.17                                   
REMARK 500    LYS B  88      -33.35   -144.54                                   
REMARK 500    ILE B 105      -71.68   -117.10                                   
REMARK 500    ARG D  68       17.23   -140.79                                   
REMARK 500    SER D 100       46.73    -76.62                                   
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 700                                                                      
REMARK 700 SHEET                                                                
REMARK 700 THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN               
REMARK 700 ORDER TO REPRESENT THIS FEATURE IN THE SHEET RECORDS BELOW,          
REMARK 700 TWO SHEETS ARE DEFINED.                                              
REMARK 900                                                                      
REMARK 900 RELATED ENTRIES                                                      
REMARK 900 RELATED ID: 132L   RELATED DB: PDB                                   
REMARK 900  LYSOZYME                                                            
REMARK 900 RELATED ID: 193L   RELATED DB: PDB                                   
REMARK 900  THE 1.33 A STRUCTURE OF TETRAGONAL HEN                              
REMARK 900  EGG WHITE LYSOZYME                                                  
REMARK 900 RELATED ID: 194L   RELATED DB: PDB                                   
REMARK 900  THE 1.40 A STRUCTURE OF SPACEHAB-01 HEN                             
REMARK 900   EGG WHITE LYSOZYME                                                 
REMARK 900 RELATED ID: 1A2Y   RELATED DB: PDB                                   
REMARK 900  HEN EGG WHITE LYSOZYME, D18A MUTANT, IN                             
REMARK 900  COMPLEX WITH MOUSE MONOCLONAL ANTIBODY D1.3                         
REMARK 900 RELATED ID: 1AKI   RELATED DB: PDB                                   
REMARK 900  THE STRUCTURE OF THE ORTHORHOMBIC FORM OF                           
REMARK 900  HEN EGG-WHITE LYSOZYME AT 1.5 ANGSTROMS RESOLUTION                  
REMARK 900 RELATED ID: 1AT5   RELATED DB: PDB                                   
REMARK 900  HEN EGG WHITE LYSOZYME WITH A SUCCINIMIDE RESIDUE                   
REMARK 900 RELATED ID: 1AT6   RELATED DB: PDB                                   
REMARK 900  HEN EGG WHITE LYSOZYME WITH A ISOASPARTATE RESIDUE                  
REMARK 900 RELATED ID: 1AZF   RELATED DB: PDB                                   
REMARK 900  CHICKEN EGG WHITE LYSOZYME CRYSTAL GROWN IN                         
REMARK 900   BROMIDE SOLUTION                                                   
REMARK 900 RELATED ID: 1B0D   RELATED DB: PDB                                   
REMARK 900  STRUCTURAL EFFECTS OF MONOVALENT ANIONS ON                          
REMARK 900  POLYMORPHIC LYSOZYME CRYSTALS                                       
REMARK 900 RELATED ID: 1B2K   RELATED DB: PDB                                   
REMARK 900  STRUCTURAL EFFECTS OF MONOVALENT ANIONS ON                          
REMARK 900  POLYMORPHIC LYSOZYME CRYSTALS                                       
REMARK 900 RELATED ID: 1BGI   RELATED DB: PDB                                   
REMARK 900  ORTHORHOMBIC LYSOZYME CRYSTALLIZED AT HIGH                          
REMARK 900  TEMPERATURE (310K)                                                  
REMARK 900 RELATED ID: 1BHZ   RELATED DB: PDB                                   
REMARK 900  LOW TEMPERATURE MIDDLE RESOLUTION STRUCTURE OF                      
REMARK 900   HEN EGG WHITE LYSOZYME FROM MASC DATA                              
REMARK 900 RELATED ID: 1BVK   RELATED DB: PDB                                   
REMARK 900  HUMANIZED ANTI-LYSOZYME FV COMPLEXED WITH LYSOZYME                  
REMARK 900 RELATED ID: 1BVX   RELATED DB: PDB                                   
REMARK 900  THE 1.8 A STRUCTURE OF GEL GROWN                                    
REMARK 900  TETRAGONAL HEN EGG WHITE LYSOZYME                                   
REMARK 900 RELATED ID: 1BWH   RELATED DB: PDB                                   
REMARK 900  THE 1.8 A STRUCTURE OF GROUND CONTROL                               
REMARK 900  GROWN TETRAGONAL HEN EGG WHITE LYSOZYME                             
REMARK 900 RELATED ID: 1BWI   RELATED DB: PDB                                   
REMARK 900  THE 1.8 A STRUCTURE OF MICROBATCH OIL                               
REMARK 900  DROP GROWN TETRAGONAL HEN EGG WHITE LYSOZYME                        
REMARK 900 RELATED ID: 1BWJ   RELATED DB: PDB                                   
REMARK 900  THE 1.8 A STRUCTURE OF MICROGRAVITY GROWN                           
REMARK 900   TETRAGONAL HEN EGG WHITE LYSOZYME                                  
REMARK 900 RELATED ID: 1C08   RELATED DB: PDB                                   
REMARK 900  CRYSTAL STRUCTURE OF HYHEL-10 FV-HEN                                
REMARK 900  LYSOZYME COMPLEX                                                    
REMARK 900 RELATED ID: 1C10   RELATED DB: PDB                                   
REMARK 900  CRYSTAL STRUCTURE OF HEW LYSOZYME UNDER                             
REMARK 900  PRESSURE OF XENON (8 BAR)                                           
REMARK 900 RELATED ID: 1DPW   RELATED DB: PDB                                   
REMARK 900  STRUCTURE OF HEN EGG-WHITE LYSOZYME IN                              
REMARK 900  COMPLEX WITH MPD                                                    
REMARK 900 RELATED ID: 1DPX   RELATED DB: PDB                                   
REMARK 900  STRUCTURE OF HEN EGG-WHITE LYSOZYME                                 
REMARK 900 RELATED ID: 1DQJ   RELATED DB: PDB                                   
REMARK 900  CRYSTAL STRUCTURE OF THE ANTI-LYSOZYME                              
REMARK 900  ANTIBODY HYHEL-63 COMPLEXED WITH HEN EGG                            
REMARK 900  WHITE LYSOZYME                                                      
REMARK 900 RELATED ID: 1E8L   RELATED DB: PDB                                   
REMARK 900  NMR SOLUTION STRUCTURE OF HEN LYSOZYME                              
REMARK 900 RELATED ID: 1F0W   RELATED DB: PDB                                   
REMARK 900  CRYSTAL STRUCTURE OF ORTHORHOMBIC LYSOZYME                          
REMARK 900  GROWN AT PH 6.5                                                     
REMARK 900 RELATED ID: 1F10   RELATED DB: PDB                                   
REMARK 900  CRYSTAL STRUCTURE OF ORTHORHOMBIC LYSOZYME                          
REMARK 900  GROWN AT PH 6.5 AT 88% RELATIVE HUMIDITY                            
REMARK 900 RELATED ID: 1F3J   RELATED DB: PDB                                   
REMARK 900  HISTOCOMPATIBILITY ANTIGEN I-AG7                                    
REMARK 900 RELATED ID: 1FDL   RELATED DB: PDB                                   
REMARK 900  IGG1 FAB FRAGMENT (ANTI-LYSOZYME ANTIBODY D1                        
REMARK 900  .3, KAPPA) - LYSOZYME COMPLEX                                       
REMARK 900 RELATED ID: 1FLQ   RELATED DB: PDB                                   
REMARK 900  HEN EGG WHITE LYSOZYME MUTANT WITH ALANINE                          
REMARK 900  SUBSTITUTED FORGLYCINE                                              
REMARK 900 RELATED ID: 1FLU   RELATED DB: PDB                                   
REMARK 900  HEN EGG WHITE LYSOZYME MUTANT WITH ALANINE                          
REMARK 900  SUBSTITUTED FORGLYCINE                                              
REMARK 900 RELATED ID: 1FLW   RELATED DB: PDB                                   
REMARK 900  HEN EGG WHITE LYSOZYME MUTANT WITH ALANINE                          
REMARK 900  SUBSTITUTED FORGLYCINE                                              
REMARK 900 RELATED ID: 1FLY   RELATED DB: PDB                                   
REMARK 900  HEN EGG WHITE LYSOZYME MUTANT WITH ALANINE                          
REMARK 900  SUBSTITUTED FORGLYCINE                                              
REMARK 900 RELATED ID: 1FN5   RELATED DB: PDB                                   
REMARK 900  HEN EGG WHITE LYSOZYME MUTANT WITH ALANINE                          
REMARK 900  SUBSTITUTED FORGLYCINE                                              
REMARK 900 RELATED ID: 1G7H   RELATED DB: PDB                                   
REMARK 900  CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME                         
REMARK 900   (HEL) COMPLEXEDWITH THE MUTANT ANTI-HEL                            
REMARK 900  MONOCLONAL ANTIBODY D1.3(VLW92A)                                    
REMARK 900 RELATED ID: 1G7I   RELATED DB: PDB                                   
REMARK 900  CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME                         
REMARK 900   (HEL) COMPLEXEDWITH THE MUTANT ANTI-HEL                            
REMARK 900  MONOCLONAL ANTIBODY D1.3 (VLW92F)                                   
REMARK 900 RELATED ID: 1G7J   RELATED DB: PDB                                   
REMARK 900  CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME                         
REMARK 900   (HEL) COMPLEXEDWITH THE MUTANT ANTI-HEL                            
REMARK 900  MONOCLONAL ANTIBODY D1.3 (VLW92H)                                   
REMARK 900 RELATED ID: 1G7L   RELATED DB: PDB                                   
REMARK 900  CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME                         
REMARK 900   (HEL) COMPLEXEDWITH THE MUTANT ANTI-HEL                            
REMARK 900  MONOCLONAL ANTIBODY D1.3 (VLW92S)                                   
REMARK 900 RELATED ID: 1G7M   RELATED DB: PDB                                   
REMARK 900  CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME                         
REMARK 900   (HEL) COMPLEXEDWITH THE MUTANT ANTI-HEL                            
REMARK 900  MONOCLONAL ANTIBODY D1.3 (VLW92V)                                   
REMARK 900 RELATED ID: 1H6M   RELATED DB: PDB                                   
REMARK 900  COVALENT GLYCOSYL-ENZYME INTERMEDIATE OF HEN                        
REMARK 900  EGG WHITE LYSOZYME                                                  
REMARK 900 RELATED ID: 1H87   RELATED DB: PDB                                   
REMARK 900  GADOLINIUM DERIVATIVE OF TETRAGONAL HEN EGG-                        
REMARK 900  WHITE LYSOZYME AT 1.7 A RESOLUTION                                  
REMARK 900 RELATED ID: 1HC0   RELATED DB: PDB                                   
REMARK 900  STRUCTURE OF LYSOZYME WITH PERIODATE                                
REMARK 900 RELATED ID: 1HEL   RELATED DB: PDB                                   
REMARK 900  HEN EGG-WHITE LYSOZYME WILD TYPE                                    
REMARK 900 RELATED ID: 1HEM   RELATED DB: PDB                                   
REMARK 900  LYSOZYME MUTANT WITH SER 91 REPLACED BY                             
REMARK 900  THR (S91T)                                                          
REMARK 900 RELATED ID: 1HEN   RELATED DB: PDB                                   
REMARK 900  LYSOZYME MUTANT WITH ILE 55 REPLACED BY                             
REMARK 900  VAL AND SER 91 REPLACED BY THR (I55V,S91T)                          
REMARK 900 RELATED ID: 1HEO   RELATED DB: PDB                                   
REMARK 900  LYSOZYME MUTANT WITH ILE 55 REPLACED BY                             
REMARK 900  VAL (I55V)                                                          
REMARK 900 RELATED ID: 1HEP   RELATED DB: PDB                                   
REMARK 900  LYSOZYME MUTANT WITH THR 40 REPLACED BY                             
REMARK 900  SER, ILE 55 REPLACED BY VAL, AND SER 91                             
REMARK 900   REPLACED BY THR (T40S,I55V,S91T)                                   
REMARK 900 RELATED ID: 1HEQ   RELATED DB: PDB                                   
REMARK 900  LYSOZYME MUTANT WITH THR 40 REPLACED BY                             
REMARK 900  SER AND SER 91 REPLACED BY THR (T40S,S91T)                          
REMARK 900 RELATED ID: 1HER   RELATED DB: PDB                                   
REMARK 900  LYSOZYME MUTANT WITH THR 40 REPLACED BY SER (T40S)                  
REMARK 900 RELATED ID: 1HEW   RELATED DB: PDB                                   
REMARK 900  LYSOZYME COMPLEXED WITH THE INHIBITOR TRI-N                         
REMARK 900  -ACETYLCHITOTRIOSE                                                  
REMARK 900 RELATED ID: 1HF4   RELATED DB: PDB                                   
REMARK 900  STRUCTURAL EFFECTS OF MONOVALENT ANIONS ON                          
REMARK 900  POLYMORPHIC LYSOZYME CRYSTALS                                       
REMARK 900 RELATED ID: 1HSW   RELATED DB: PDB                                   
REMARK 900  LYSOZYME (MUCOPEPTIDE N-ACETYLMURAMYL HYDROLASE)                    
REMARK 900 RELATED ID: 1HSX   RELATED DB: PDB                                   
REMARK 900  LYSOZYME GROWN AT BASIC PH AND ITS LOW                              
REMARK 900  HUMIDITY VARIANT                                                    
REMARK 900 RELATED ID: 1IC4   RELATED DB: PDB                                   
REMARK 900  CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(                            
REMARK 900  HD32A)-HEN LYSOZYMECOMPLEX                                          
REMARK 900 RELATED ID: 1IC5   RELATED DB: PDB                                   
REMARK 900  CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(                            
REMARK 900  HD99A)-HEN LYSOZYMECOMPLEX                                          
REMARK 900 RELATED ID: 1IC7   RELATED DB: PDB                                   
REMARK 900  CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(                            
REMARK 900  HD32A99A)-HENLYSOZYME COMPLEX                                       
REMARK 900 RELATED ID: 1IEE   RELATED DB: PDB                                   
REMARK 900  STRUCTURE OF TETRAGONAL HEN EGG WHITE                               
REMARK 900  LYSOZYME AT 0.94 AFROM CRYSTALS GROWN BY                            
REMARK 900  THE COUNTER-DIFFUSION METHOD                                        
REMARK 900 RELATED ID: 1IO5   RELATED DB: PDB                                   
REMARK 900  HYDROGEN AND HYDRATION OF HEN EGG-WHITE                             
REMARK 900  LYSOZYME DETERMINEDBY NEUTRON DIFFRACTION                           
REMARK 900 RELATED ID: 1IOQ   RELATED DB: PDB                                   
REMARK 900  STABILIZATION OF HEN EGG WHITE LYSOZYME BY                          
REMARK 900  A CAVITY-FILLINGMUTATION                                            
REMARK 900 RELATED ID: 1IOR   RELATED DB: PDB                                   
REMARK 900  STABILIZATION OF HEN EGG WHITE LYSOZYME BY                          
REMARK 900  A CAVITY-FILLINGMUTATION                                            
REMARK 900 RELATED ID: 1IOS   RELATED DB: PDB                                   
REMARK 900  STABILIZATION OF HEN EGG WHITE LYSOZYME BY                          
REMARK 900  A CAVITY-FILLINGMUTATION                                            
REMARK 900 RELATED ID: 1IOT   RELATED DB: PDB                                   
REMARK 900  STABILIZATION OF HEN EGG WHITE LYSOZYME BY                          
REMARK 900  A CAVITY-FILLINGMUTATION                                            
REMARK 900 RELATED ID: 1JA2   RELATED DB: PDB                                   
REMARK 900  BINDING OF N-ACETYLGLUCOSAMINE TO CHICKEN                           
REMARK 900  EGG LYSOZYME: APOWDER DIFFRACTION STUDY                             
REMARK 900 RELATED ID: 1JA4   RELATED DB: PDB                                   
REMARK 900  BINDING OF N-ACETYLGLUCOSAMINE TO CHICKEN                           
REMARK 900  EGG LYSOZYME: APOWDER DIFFRACTION STUDY                             
REMARK 900 RELATED ID: 1JA6   RELATED DB: PDB                                   
REMARK 900  BINDING OF N-ACETYLGLUCOSAMINE TO CHICKEN                           
REMARK 900  EGG LYSOZYME: APOWDER DIFFRACTION STUDY                             
REMARK 900 RELATED ID: 1JA7   RELATED DB: PDB                                   
REMARK 900  BINDING OF N-ACETYLGLUCOSAMINE TO CHICKEN                           
REMARK 900  EGG LYSOZYME: APOWDER DIFFRACTION STUDY                             
REMARK 900 RELATED ID: 1JPO   RELATED DB: PDB                                   
REMARK 900  LOW TEMPERATURE ORTHORHOMBIC LYSOZYME                               
REMARK 900 RELATED ID: 1JTO   RELATED DB: PDB                                   
REMARK 900  DEGENERATE INTERFACES IN ANTIGEN-ANTIBODY                           
REMARK 900  COMPLEXES                                                           
REMARK 900 RELATED ID: 1KIP   RELATED DB: PDB                                   
REMARK 900  FV MUTANT Y(B 32)A (VH DOMAIN) OF                                   
REMARK 900  MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED                            
REMARK 900  WITH HEN EGG WHITE LYSOZYME                                         
REMARK 900 RELATED ID: 1KIQ   RELATED DB: PDB                                   
REMARK 900  FV MUTANT Y(B 101)F (VH DOMAIN) OF                                  
REMARK 900  MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED                            
REMARK 900  WITH HEN EGG WHITE LYSOZYME                                         
REMARK 900 RELATED ID: 1KIR   RELATED DB: PDB                                   
REMARK 900  FV MUTANT Y(A 50)S (VL DOMAIN) OF                                   
REMARK 900  MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED                            
REMARK 900  WITH HEN EGG WHITE LYSOZYME                                         
REMARK 900 RELATED ID: 1KXW   RELATED DB: PDB                                   
REMARK 900  ANALYSIS OF THE STABILIZATION OF HEN                                
REMARK 900  LYSOZYME WITH THE HELIX DIPOLE AND CHARGED                          
REMARK 900  SIDE CHAINS                                                         
REMARK 900 RELATED ID: 1KXX   RELATED DB: PDB                                   
REMARK 900  ANALYSIS OF THE STABILIZATION OF HEN                                
REMARK 900  LYSOZYME WITH THE HELIX DIPOLE AND CHARGED                          
REMARK 900  SIDE CHAINS                                                         
REMARK 900 RELATED ID: 1KXY   RELATED DB: PDB                                   
REMARK 900  ANALYSIS OF THE STABILIZATION OF HEN                                
REMARK 900  LYSOZYME WITH THE HELIX DIPOLE AND CHARGED                          
REMARK 900  SIDE CHAINS                                                         
REMARK 900 RELATED ID: 1LCN   RELATED DB: PDB                                   
REMARK 900  MONOCLINIC HEN EGG WHITE LYSOZYME, THIOCYANATE                      
REMARK 900   COMPLEX                                                            
REMARK 900 RELATED ID: 1LKR   RELATED DB: PDB                                   
REMARK 900  MONOCLINIC HEN EGG WHITE LYSOZYME IODIDE                            
REMARK 900 RELATED ID: 1LKS   RELATED DB: PDB                                   
REMARK 900  HEN EGG WHITE LYSOZYME NITRATE                                      
REMARK 900 RELATED ID: 1LMA   RELATED DB: PDB                                   
REMARK 900  LYSOZYME (88 PERCENT HUMIDITY)                                      
REMARK 900 RELATED ID: 1LPI   RELATED DB: PDB                                   
REMARK 900  HEW LYSOZYME: TRP...NA CATION-PI INTERACTION                        
REMARK 900 RELATED ID: 1LSA   RELATED DB: PDB                                   
REMARK 900  LYSOZYME (120 K)                                                    
REMARK 900 RELATED ID: 1LSB   RELATED DB: PDB                                   
REMARK 900  LYSOZYME (180 K)                                                    
REMARK 900 RELATED ID: 1LSC   RELATED DB: PDB                                   
REMARK 900  LYSOZYME (250 K)                                                    
REMARK 900 RELATED ID: 1LSD   RELATED DB: PDB                                   
REMARK 900  LYSOZYME (280 K)                                                    
REMARK 900 RELATED ID: 1LSE   RELATED DB: PDB                                   
REMARK 900  LYSOZYME (295 K)                                                    
REMARK 900 RELATED ID: 1LSF   RELATED DB: PDB                                   
REMARK 900  LYSOZYME (95 K)                                                     
REMARK 900 RELATED ID: 1LSG   RELATED DB: PDB                                   
REMARK 900  MOL_ID: 1; MOLECULE: LYSOZYME MODIFIED WITH                         
REMARK 900  HUMAN FIBRINOGEN GAMMA; CHAIN: NULL;                                
REMARK 900  ENGINEERED; THE 14-RESIDUE C-TERMINUS (                             
REMARK 900  RESIDUES 398 - 411) OF THE HUMAN FIBRINOGEN                         
REMARK 900   GAMMA CHAIN FUSED TO THE C-TERMINUS OF                             
REMARK 900  CHICKEN EGG WHITE LYSOZYME; MUTATION: N-TERM                        
REMARK 900   MET                                                                
REMARK 900 RELATED ID: 1LSM   RELATED DB: PDB                                   
REMARK 900  LYSOZYME MUTANT WITH ILE 55 REPLACED BY                             
REMARK 900  LEU, SER 91 REPLACED BY THR, AND ASP 101                            
REMARK 900   REPLACED BY SER (I55L,S91T,D101S)                                  
REMARK 900 RELATED ID: 1LSN   RELATED DB: PDB                                   
REMARK 900  LYSOZYME MUTANT WITH SER 91 REPLACED BY ALA (S91A)                  
REMARK 900 RELATED ID: 1LSY   RELATED DB: PDB                                   
REMARK 900  LYSOZYME MUTANT WITH ASP 52 REPLACED BY SER (D52S)                  
REMARK 900 RELATED ID: 1LSZ   RELATED DB: PDB                                   
REMARK 900  LYSOZYME MUTANT WITH ASP 52 REPLACED BY                             
REMARK 900  SER (D52S) COMPLEXED WITH GLCNAC4 (TETRA-N-                         
REMARK 900  ACETYL CHITOTETRAOSE)                                               
REMARK 900 RELATED ID: 1LYO   RELATED DB: PDB                                   
REMARK 900  CROSS-LINKED LYSOZYME CRYSTAL IN NEAT WATER                         
REMARK 900 RELATED ID: 1LYS   RELATED DB: PDB                                   
REMARK 900  LYSOZYME                                                            
REMARK 900 RELATED ID: 1LYZ   RELATED DB: PDB                                   
REMARK 900  LYSOZYME                                                            
REMARK 900 RELATED ID: 1LZ8   RELATED DB: PDB                                   
REMARK 900  LYSOZYME PHASED ON ANOMALOUS SIGNAL OF                              
REMARK 900  SULFURS AND CHLORINES                                               
REMARK 900 RELATED ID: 1LZ9   RELATED DB: PDB                                   
REMARK 900  ANOMALOUS SIGNAL OF SOLVENT BROMINES USED                           
REMARK 900  FOR PHASING OF LYSOZYME                                             
REMARK 900 RELATED ID: 1LZA   RELATED DB: PDB                                   
REMARK 900  LYSOZYME                                                            
REMARK 900 RELATED ID: 1LZB   RELATED DB: PDB                                   
REMARK 900  LYSOZYME CO-CRYSTALLIZED WITH TRI-N-ACETYL-                         
REMARK 900  CHITOTRIOSE (PH 4.7)                                                
REMARK 900 RELATED ID: 1LZC   RELATED DB: PDB                                   
REMARK 900  LYSOZYME CO-CRYSTALLIZED WITH TETRA-N-ACETYL                        
REMARK 900  -CHITOTETRAOSE (PH 4.7)                                             
REMARK 900 RELATED ID: 1LZD   RELATED DB: PDB                                   
REMARK 900  LYSOZYME MUTANT WITH TRP 62 REPLACED BY TYR (W62Y)                  
REMARK 900 RELATED ID: 1LZE   RELATED DB: PDB                                   
REMARK 900  LYSOZYME MUTANT WITH TRP 62 REPLACED BY                             
REMARK 900  TYR (W62Y) CO-CRYSTALLIZED WITH TRI-N-                              
REMARK 900  ACETYL-CHITOTRIOSE (PH 4.7)                                         
REMARK 900 RELATED ID: 1LZG   RELATED DB: PDB                                   
REMARK 900  LYSOZYME MUTANT WITH TRP 62 REPLACED BY                             
REMARK 900  PHE (W62F) CO-CRYSTALLIZED WITH TRI-N-                              
REMARK 900  ACETYL-CHITOTRIOSE (PH 4.7)                                         
REMARK 900 RELATED ID: 1LZH   RELATED DB: PDB                                   
REMARK 900  LYSOZYME (MONOCLINIC)                                               
REMARK 900 RELATED ID: 1LZN   RELATED DB: PDB                                   
REMARK 900  NEUTRON STRUCTURE OF HEN EGG-WHITE LYSOZYME                         
REMARK 900 RELATED ID: 1LZT   RELATED DB: PDB                                   
REMARK 900  LYSOZYME , TRICLINIC CRYSTAL FORM                                   
REMARK 900 RELATED ID: 1MEL   RELATED DB: PDB                                   
REMARK 900  CRYSTAL STRUCTURE OF A CAMEL SINGLE-DOMAIN                          
REMARK 900  VH ANTIBODY FRAGMENT IN COMPLEX WITH                                
REMARK 900  LYSOZYME                                                            
REMARK 900 RELATED ID: 1MLC   RELATED DB: PDB                                   
REMARK 900  MONOCLONAL ANTIBODY FAB D44.1 RAISED AGAINST                        
REMARK 900   CHICKEN EGG-WHITE LYSOZYME COMPLEXED WITH                          
REMARK 900  LYSOZYME                                                            
REMARK 900 RELATED ID: 1QIO   RELATED DB: PDB                                   
REMARK 900  SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE CAUSED                      
REMARK 900   BY INTENSE SYNCHROTRON RADIATION TO HEN                            
REMARK 900  EGG WHITE LYSOZYME                                                  
REMARK 900 RELATED ID: 1QTK   RELATED DB: PDB                                   
REMARK 900  CRYSTAL STRUCTURE OF HEW LYSOZYME UNDER                             
REMARK 900  PRESSURE OF KRYPTON (55 BAR)                                        
REMARK 900 RELATED ID: 1RCM   RELATED DB: PDB                                   
REMARK 900  LYSOZYME (PARTIALLY REDUCED, CARBOXYMETHYLATED                      
REMARK 900  (6,127-RCM))                                                        
REMARK 900 RELATED ID: 1RFP   RELATED DB: PDB                                   
REMARK 900  ANALYSIS OF THE STABILIZATION OF HEN                                
REMARK 900  LYSOZYME WITH THE HELIX DIPOLE AND CHARGED                          
REMARK 900  SIDE CHAINS                                                         
REMARK 900 RELATED ID: 1UCO   RELATED DB: PDB                                   
REMARK 900  HEN EGG-WHITE LYSOZYME, LOW HUMIDITY FORM                           
REMARK 900 RELATED ID: 1UIA   RELATED DB: PDB                                   
REMARK 900  ANALYSIS OF THE STABILIZATION OF HEN                                
REMARK 900  LYSOZYME WITH THE HELIX DIPOLE AND CHARGED                          
REMARK 900  SIDE CHAINS                                                         
REMARK 900 RELATED ID: 1UIB   RELATED DB: PDB                                   
REMARK 900  ANALYSIS OF THE STABILIZATION OF HEN                                
REMARK 900  LYSOZYME WITH THE HELIX DIPOLE AND CHARGED                          
REMARK 900  SIDE CHAINS                                                         
REMARK 900 RELATED ID: 1UIC   RELATED DB: PDB                                   
REMARK 900  ANALYSIS OF THE STABILIZATION OF HEN                                
REMARK 900  LYSOZYME WITH THE HELIX DIPOLE AND CHARGED                          
REMARK 900  SIDE CHAINS                                                         
REMARK 900 RELATED ID: 1UID   RELATED DB: PDB                                   
REMARK 900  ANALYSIS OF THE STABILIZATION OF HEN                                
REMARK 900  LYSOZYME WITH THE HELIX DIPOLE AND CHARGED                          
REMARK 900  SIDE CHAINS                                                         
REMARK 900 RELATED ID: 1UIE   RELATED DB: PDB                                   
REMARK 900  ANALYSIS OF THE STABILIZATION OF HEN                                
REMARK 900  LYSOZYME WITH THE HELIX DIPOLE AND CHARGED                          
REMARK 900  SIDE CHAINS                                                         
REMARK 900 RELATED ID: 1UIF   RELATED DB: PDB                                   
REMARK 900  ANALYSIS OF THE STABILIZATION OF HEN                                
REMARK 900  LYSOZYME WITH THE HELIX DIPOLE AND CHARGED                          
REMARK 900  SIDE CHAINS                                                         
REMARK 900 RELATED ID: 1UIG   RELATED DB: PDB                                   
REMARK 900  ANALYSIS OF THE STABILIZATION OF HEN                                
REMARK 900  LYSOZYME WITH THE HELIX DIPOLE AND CHARGED                          
REMARK 900  SIDE CHAINS                                                         
REMARK 900 RELATED ID: 1UIH   RELATED DB: PDB                                   
REMARK 900  ANALYSIS OF THE STABILIZATION OF HEN                                
REMARK 900  LYSOZYME WITH THE HELIX DIPOLE AND CHARGED                          
REMARK 900  SIDE CHAINS                                                         
REMARK 900 RELATED ID: 1XEI   RELATED DB: PDB                                   
REMARK 900  THE CRYSTAL STRUCTURES OF LYSOZYME AT VERY                          
REMARK 900  LOW LEVELS OF HYDRATION                                             
REMARK 900 RELATED ID: 1XEJ   RELATED DB: PDB                                   
REMARK 900  THE CRYSTAL STRUCTURES OF LYSOZYME AT VERY                          
REMARK 900  LOW LEVELS OF HYDRATION                                             
REMARK 900 RELATED ID: 1XEK   RELATED DB: PDB                                   
REMARK 900  THE CRYSTAL STRUCTURES OF LYSOZYME AT VERY                          
REMARK 900  LOW LEVELS OF HYDRATION                                             
REMARK 900 RELATED ID: 2HFM   RELATED DB: PDB                                   
REMARK 900  IGG1 FV FRAGMENT (HYHEL-10) AND LYSOZYME                            
REMARK 900  COMPLEX (THEORETICAL MODEL)                                         
REMARK 900 RELATED ID: 2IFF   RELATED DB: PDB                                   
REMARK 900  IGG1 FAB FRAGMENT (HYHEL-5) COMPLEXED WITH                          
REMARK 900  LYSOZYME MUTANT WITH ARG 68 REPLACED BY                             
REMARK 900  LYS (R68K)                                                          
REMARK 900 RELATED ID: 2LYM   RELATED DB: PDB                                   
REMARK 900  LYSOZYME (1 ATMOSPHERE, 1.4 M NACL)                                 
REMARK 900 RELATED ID: 2LYO   RELATED DB: PDB                                   
REMARK 900  CROSS-LINKED CHICKEN LYSOZYME CRYSTAL IN 90                         
REMARK 900  % ACETONITRILE-WATER                                                
REMARK 900 RELATED ID: 2LYZ   RELATED DB: PDB                                   
REMARK 900  LYSOZYME                                                            
REMARK 900 RELATED ID: 2LZH   RELATED DB: PDB                                   
REMARK 900  LYSOZYME (ORTHORHOMBIC)                                             
REMARK 900 RELATED ID: 2LZT   RELATED DB: PDB                                   
REMARK 900  LYSOZYME , TRICLINIC CRYSTAL FORM                                   
REMARK 900 RELATED ID: 3HFL   RELATED DB: PDB                                   
REMARK 900  IGG1 FAB FRAGMENT (HY/HEL-5) COMPLEXED                              
REMARK 900  WITH LYSOZYME                                                       
REMARK 900 RELATED ID: 3HFM   RELATED DB: PDB                                   
REMARK 900  IGG1 FAB FRAGMENT (HYHEL-10) AND LYSOZYME COMPLEX                   
REMARK 900 RELATED ID: 3LYM   RELATED DB: PDB                                   
REMARK 900  LYSOZYME (1000 ATMOSPHERES, 1.4 M NACL)                             
REMARK 900 RELATED ID: 3LYO   RELATED DB: PDB                                   
REMARK 900  CROSS-LINKED CHICKEN LYSOZYME CRYSTAL IN 95                         
REMARK 900  % ACETONITRILE-WATER                                                
REMARK 900 RELATED ID: 3LYT   RELATED DB: PDB                                   
REMARK 900  LYSOZYME (100 KELVIN)                                               
REMARK 900 RELATED ID: 3LYZ   RELATED DB: PDB                                   
REMARK 900  LYSOZYME                                                            
REMARK 900 RELATED ID: 3LZT   RELATED DB: PDB                                   
REMARK 900  REFINEMENT OF TRICLINIC LYSOZYME AT ATOMIC                          
REMARK 900  RESOLUTION                                                          
REMARK 900 RELATED ID: 4LYM   RELATED DB: PDB                                   
REMARK 900  LYSOZYME (MUCOPEPTIDE N-ACETYLMURAMYL HYDROLASE)                    
REMARK 900 RELATED ID: 4LYO   RELATED DB: PDB                                   
REMARK 900  CROSS-LINKED CHICKEN LYSOZYME CRYSTAL IN                            
REMARK 900  NEAT ACETONITRILE, THEN BACK-SOAKED IN WATER                        
REMARK 900 RELATED ID: 4LYT   RELATED DB: PDB                                   
REMARK 900  LYSOZYME (298 KELVIN)                                               
REMARK 900 RELATED ID: 4LYZ   RELATED DB: PDB                                   
REMARK 900  LYSOZYME                                                            
REMARK 900 RELATED ID: 4LZT   RELATED DB: PDB                                   
REMARK 900  ATOMIC RESOLUTION REFINEMENT OF TRICLINIC HEW                       
REMARK 900   LYSOZYME AT 295K                                                   
REMARK 900 RELATED ID: 5LYM   RELATED DB: PDB                                   
REMARK 900  STUDIES OF MONOCLINIC HEN EGG WHITE LYSOZYME. IV.                   
REMARK 900  X-RAY REFINEMENT AT 1.8 ANGSTROM RESOLUTION AND A                   
REMARK 900  COMPARISON OF THE VARIABLE REGIONS IN THE POLYMORPHIC FORMS         
REMARK 900 RELATED ID: 5LYT   RELATED DB: PDB                                   
REMARK 900  LYSOZYME (100 KELVIN)                                               
REMARK 900 RELATED ID: 5LYZ   RELATED DB: PDB                                   
REMARK 900  LYSOZYME                                                            
REMARK 900 RELATED ID: 6LYT   RELATED DB: PDB                                   
REMARK 900  LYSOZYME (298 KELVIN)                                               
REMARK 900 RELATED ID: 6LYZ   RELATED DB: PDB                                   
REMARK 900  LYSOZYME                                                            
REMARK 900 RELATED ID: 7LYZ   RELATED DB: PDB                                   
REMARK 900  LYSOZYME TRICLINIC CRYSTAL FORM                                     
REMARK 900 RELATED ID: 8LYZ   RELATED DB: PDB                                   
REMARK 900  LYSOZYME IODINE-INACTIVATED                                         
DBREF  1GPQ A    1   129  UNP    P45502   IVY_ECOLI       29    157             
DBREF  1GPQ B    1   129  UNP    P45502   IVY_ECOLI       29    157             
DBREF  1GPQ C    1   129  UNP    P00698   LYC_CHICK       19    147             
DBREF  1GPQ D    1   129  UNP    P00698   LYC_CHICK       19    147             
SEQADV 1GPQ ARG A  129  UNP  P45502    LYS   157 CONFLICT                       
SEQADV 1GPQ HIS A  130  UNP  E7H715              EXPRESSION TAG                 
SEQADV 1GPQ HIS A  131  UNP  E7H715              EXPRESSION TAG                 
SEQADV 1GPQ HIS A  132  UNP  E7H715              EXPRESSION TAG                 
SEQADV 1GPQ HIS A  133  UNP  E7H715              EXPRESSION TAG                 
SEQADV 1GPQ HIS A  134  UNP  E7H715              EXPRESSION TAG                 
SEQADV 1GPQ HIS A  135  UNP  E7H715              EXPRESSION TAG                 
SEQADV 1GPQ ARG B  129  UNP  P45502    LYS   157 CONFLICT                       
SEQADV 1GPQ HIS B  130  UNP  E7H715              EXPRESSION TAG                 
SEQADV 1GPQ HIS B  131  UNP  E7H715              EXPRESSION TAG                 
SEQADV 1GPQ HIS B  132  UNP  E7H715              EXPRESSION TAG                 
SEQADV 1GPQ HIS B  133  UNP  E7H715              EXPRESSION TAG                 
SEQADV 1GPQ HIS B  134  UNP  E7H715              EXPRESSION TAG                 
SEQADV 1GPQ HIS B  135  UNP  E7H715              EXPRESSION TAG                 
SEQRES   1 A  135  GLN ASP ASP LEU THR ILE SER SER LEU ALA LYS GLY GLU          
SEQRES   2 A  135  THR THR LYS ALA ALA PHE ASN GLN MET VAL GLN GLY HIS          
SEQRES   3 A  135  LYS LEU PRO ALA TRP VAL MET LYS GLY GLY THR TYR THR          
SEQRES   4 A  135  PRO ALA GLN THR VAL THR LEU GLY ASP GLU THR TYR GLN          
SEQRES   5 A  135  VAL MET SER ALA CYS LYS PRO HIS ASP CYS GLY SER GLN          
SEQRES   6 A  135  ARG ILE ALA VAL MET TRP SER GLU LYS SER ASN GLN MET          
SEQRES   7 A  135  THR GLY LEU PHE SER THR ILE ASP GLU LYS THR SER GLN          
SEQRES   8 A  135  GLU LYS LEU THR TRP LEU ASN VAL ASN ASP ALA LEU SER          
SEQRES   9 A  135  ILE ASP GLY LYS THR VAL LEU PHE ALA ALA LEU THR GLY          
SEQRES  10 A  135  SER LEU GLU ASN HIS PRO ASP GLY PHE ASN PHE ARG HIS          
SEQRES  11 A  135  HIS HIS HIS HIS HIS                                          
SEQRES   1 B  135  GLN ASP ASP LEU THR ILE SER SER LEU ALA LYS GLY GLU          
SEQRES   2 B  135  THR THR LYS ALA ALA PHE ASN GLN MET VAL GLN GLY HIS          
SEQRES   3 B  135  LYS LEU PRO ALA TRP VAL MET LYS GLY GLY THR TYR THR          
SEQRES   4 B  135  PRO ALA GLN THR VAL THR LEU GLY ASP GLU THR TYR GLN          
SEQRES   5 B  135  VAL MET SER ALA CYS LYS PRO HIS ASP CYS GLY SER GLN          
SEQRES   6 B  135  ARG ILE ALA VAL MET TRP SER GLU LYS SER ASN GLN MET          
SEQRES   7 B  135  THR GLY LEU PHE SER THR ILE ASP GLU LYS THR SER GLN          
SEQRES   8 B  135  GLU LYS LEU THR TRP LEU ASN VAL ASN ASP ALA LEU SER          
SEQRES   9 B  135  ILE ASP GLY LYS THR VAL LEU PHE ALA ALA LEU THR GLY          
SEQRES  10 B  135  SER LEU GLU ASN HIS PRO ASP GLY PHE ASN PHE ARG HIS          
SEQRES  11 B  135  HIS HIS HIS HIS HIS                                          
SEQRES   1 C  129  LYS VAL PHE GLY ARG CYS GLU LEU ALA ALA ALA MET LYS          
SEQRES   2 C  129  ARG HIS GLY LEU ASP ASN TYR ARG GLY TYR SER LEU GLY          
SEQRES   3 C  129  ASN TRP VAL CYS ALA ALA LYS PHE GLU SER ASN PHE ASN          
SEQRES   4 C  129  THR GLN ALA THR ASN ARG ASN THR ASP GLY SER THR ASP          
SEQRES   5 C  129  TYR GLY ILE LEU GLN ILE ASN SER ARG TRP TRP CYS ASN          
SEQRES   6 C  129  ASP GLY ARG THR PRO GLY SER ARG ASN LEU CYS ASN ILE          
SEQRES   7 C  129  PRO CYS SER ALA LEU LEU SER SER ASP ILE THR ALA SER          
SEQRES   8 C  129  VAL ASN CYS ALA LYS LYS ILE VAL SER ASP GLY ASN GLY          
SEQRES   9 C  129  MET ASN ALA TRP VAL ALA TRP ARG ASN ARG CYS LYS GLY          
SEQRES  10 C  129  THR ASP VAL GLN ALA TRP ILE ARG GLY CYS ARG LEU              
SEQRES   1 D  129  LYS VAL PHE GLY ARG CYS GLU LEU ALA ALA ALA MET LYS          
SEQRES   2 D  129  ARG HIS GLY LEU ASP ASN TYR ARG GLY TYR SER LEU GLY          
SEQRES   3 D  129  ASN TRP VAL CYS ALA ALA LYS PHE GLU SER ASN PHE ASN          
SEQRES   4 D  129  THR GLN ALA THR ASN ARG ASN THR ASP GLY SER THR ASP          
SEQRES   5 D  129  TYR GLY ILE LEU GLN ILE ASN SER ARG TRP TRP CYS ASN          
SEQRES   6 D  129  ASP GLY ARG THR PRO GLY SER ARG ASN LEU CYS ASN ILE          
SEQRES   7 D  129  PRO CYS SER ALA LEU LEU SER SER ASP ILE THR ALA SER          
SEQRES   8 D  129  VAL ASN CYS ALA LYS LYS ILE VAL SER ASP GLY ASN GLY          
SEQRES   9 D  129  MET ASN ALA TRP VAL ALA TRP ARG ASN ARG CYS LYS GLY          
SEQRES  10 D  129  THR ASP VAL GLN ALA TRP ILE ARG GLY CYS ARG LEU              
FORMUL   5  HOH   *635(H2 O)                                                    
HELIX    1   1 THR A    5  GLY A   12  1                                   8    
HELIX    2   2 THR A   15  GLN A   24  1                                  10    
HELIX    3   3 ALA A   30  GLY A   35  1                                   6    
HELIX    4   4 GLU A   87  THR A   89  5                                   3    
HELIX    5   5 ASN A  100  SER A  104  5                                   5    
HELIX    6   6 ILE A  105  GLY A  117  1                                  13    
HELIX    7   7 GLY A  117  HIS A  122  1                                   6    
HELIX    8   8 THR B    5  GLY B   12  1                                   8    
HELIX    9   9 THR B   15  GLN B   24  1                                  10    
HELIX   10  10 ALA B   30  GLY B   35  1                                   6    
HELIX   11  11 ASN B  100  SER B  104  5                                   5    
HELIX   12  12 ILE B  105  GLY B  117  1                                  13    
HELIX   13  13 GLY B  117  HIS B  122  1                                   6    
HELIX   14  14 GLY C    4  HIS C   15  1                                  12    
HELIX   15  15 SER C   24  ASN C   37  1                                  14    
HELIX   16  16 CYS C   80  SER C   85  5                                   6    
HELIX   17  17 ILE C   88  SER C  100  1                                  13    
HELIX   18  18 ASN C  103  ALA C  107  5                                   5    
HELIX   19  19 TRP C  108  CYS C  115  1                                   8    
HELIX   20  20 ASP C  119  ARG C  125  5                                   7    
HELIX   21  21 GLY D    4  HIS D   15  1                                  12    
HELIX   22  22 SER D   24  ASN D   37  1                                  14    
HELIX   23  23 CYS D   80  SER D   85  5                                   6    
HELIX   24  24 ILE D   88  SER D  100  1                                  13    
HELIX   25  25 ASN D  103  ALA D  107  5                                   5    
HELIX   26  26 TRP D  108  CYS D  115  1                                   8    
HELIX   27  27 ASP D  119  ARG D  125  5                                   7    
SHEET    1  AA 3 THR A  37  TYR A  38  0                                        
SHEET    2  AA 3 GLU A  49  CYS A  57 -1  O  CYS A  57   N  THR A  37           
SHEET    3  AA 3 GLN A  42  LEU A  46 -1  O  GLN A  42   N  VAL A  53           
SHEET    1  AB 9 THR A  37  TYR A  38  0                                        
SHEET    2  AB 9 GLU A  49  CYS A  57 -1  O  CYS A  57   N  THR A  37           
SHEET    3  AB 9 GLN A  65  TRP A  71 -1  O  ILE A  67   N  ALA A  56           
SHEET    4  AB 9 MET A  78  ASP A  86 -1  O  THR A  79   N  MET A  70           
SHEET    5  AB 9 GLN A  91  LEU A  97 -1  O  GLN A  91   N  ASP A  86           
SHEET    6  AB 9 GLU B  92  LEU B  97 -1  O  GLU B  92   N  LEU A  94           
SHEET    7  AB 9 GLN B  77  ILE B  85 -1  O  GLY B  80   N  LEU B  97           
SHEET    8  AB 9 GLN B  65  SER B  72 -1  O  ARG B  66   N  SER B  83           
SHEET    9  AB 9 GLU B  49  CYS B  57 -1  O  GLN B  52   N  TRP B  71           
SHEET    1  CA 3 THR C  43  ARG C  45  0                                        
SHEET    2  CA 3 THR C  51  TYR C  53 -1  O  ASP C  52   N  ASN C  44           
SHEET    3  CA 3 ILE C  58  ASN C  59 -1  O  ILE C  58   N  TYR C  53           
SHEET    1  DA 3 THR D  43  ARG D  45  0                                        
SHEET    2  DA 3 THR D  51  TYR D  53 -1  O  ASP D  52   N  ASN D  44           
SHEET    3  DA 3 ILE D  58  ASN D  59 -1  O  ILE D  58   N  TYR D  53           
SSBOND   1 CYS A   57    CYS A   62                          1555   1555  2.05  
SSBOND   2 CYS B   57    CYS B   62                          1555   1555  2.05  
SSBOND   3 CYS C    6    CYS C  127                          1555   1555  2.03  
SSBOND   4 CYS C   30    CYS C  115                          1555   1555  2.04  
SSBOND   5 CYS C   64    CYS C   80                          1555   1555  2.03  
SSBOND   6 CYS C   76    CYS C   94                          1555   1555  2.05  
SSBOND   7 CYS D    6    CYS D  127                          1555   1555  2.04  
SSBOND   8 CYS D   30    CYS D  115                          1555   1555  2.04  
SSBOND   9 CYS D   64    CYS D   80                          1555   1555  2.04  
SSBOND  10 CYS D   76    CYS D   94                          1555   1555  2.04  
CRYST1   55.490   59.560   69.200  90.00  95.39  90.00 P 1 21 1      4          
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      0.018021  0.000000  0.001700        0.00000                         
SCALE2      0.000000  0.016790  0.000000        0.00000                         
SCALE3      0.000000  0.000000  0.014515        0.00000                         
(ATOM LINES ARE NOT SHOWN.)
END                                                                             
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