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Database: PDB
Entry: 1QGB
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Original site: 1QGB 
HEADER    CELL ADHESION                           21-APR-99   1QGB              
TITLE     SOLUTION STRUCTURE OF THE N-TERMINAL F1 MODULE PAIR FROM              
TITLE    2 HUMAN FIBRONECTIN                                                    
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: PROTEIN (FIBRONECTIN);                                     
COMPND   3 CHAIN: A;                                                            
COMPND   4 FRAGMENT: N-TERMINAL F1 MODULE PAIR;                                 
COMPND   5 ENGINEERED: YES                                                      
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE   3 ORGANISM_COMMON: HUMAN;                                              
SOURCE   4 ORGANISM_TAXID: 9606;                                                
SOURCE   5 EXPRESSION_SYSTEM: PICHIA PASTORIS;                                  
SOURCE   6 EXPRESSION_SYSTEM_TAXID: 4922;                                       
SOURCE   7 EXPRESSION_SYSTEM_STRAIN: GS115                                      
KEYWDS    FIBRONECTIN TYPE 1 MODULE PAIR, CELL ADHESION                         
EXPDTA    SOLUTION NMR                                                          
NUMMDL    24                                                                    
AUTHOR    J.R.POTTS,J.R.BRIGHT,D.BOLTON,A.R.PICKFORD,I.D.CAMPBELL               
REVDAT   2   24-FEB-09 1QGB    1       VERSN                                    
REVDAT   1   08-DEC-99 1QGB    0                                                
JRNL        AUTH   J.R.POTTS,J.R.BRIGHT,D.BOLTON,A.R.PICKFORD,                  
JRNL        AUTH 2 I.D.CAMPBELL                                                 
JRNL        TITL   SOLUTION STRUCTURE OF THE N-TERMINAL F1 MODULE               
JRNL        TITL 2 PAIR FROM HUMAN FIBRONECTIN.                                 
JRNL        REF    BIOCHEMISTRY                  V.  38  8304 1999              
JRNL        REFN                   ISSN 0006-2960                               
JRNL        PMID   10387076                                                     
JRNL        DOI    10.1021/BI990202B                                            
REMARK   1                                                                      
REMARK   2                                                                      
REMARK   2 RESOLUTION. NOT APPLICABLE.                                          
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   PROGRAM     : X-PLOR 3.851                                         
REMARK   3   AUTHORS     : BRUNGER                                              
REMARK   3                                                                      
REMARK   3  OTHER REFINEMENT REMARKS: REFINEMENT DETAILS CAN BE FOUND IN        
REMARK   3  THE JRNL CITATION ABOVE.                                            
REMARK   4                                                                      
REMARK   4 1QGB COMPLIES WITH FORMAT V. 3.15, 01-DEC-08                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 27-APR-99.                  
REMARK 100 THE RCSB ID CODE IS RCSB000929.                                      
REMARK 210                                                                      
REMARK 210 EXPERIMENTAL DETAILS                                                 
REMARK 210  EXPERIMENT TYPE                : NMR                                
REMARK 210  TEMPERATURE           (KELVIN) : 310                                
REMARK 210  PH                             : 4.0                                
REMARK 210  IONIC STRENGTH                 : NULL                               
REMARK 210  PRESSURE                       : NULL                               
REMARK 210  SAMPLE CONTENTS                : NULL                               
REMARK 210                                                                      
REMARK 210  NMR EXPERIMENTS CONDUCTED      : COSY, TOCSY, NOESY, 3D-NOESY-      
REMARK 210                                   HSQC                               
REMARK 210  SPECTROMETER FIELD STRENGTH    : 600 MHZ, 750 MHZ                   
REMARK 210  SPECTROMETER MODEL             : NULL                               
REMARK 210  SPECTROMETER MANUFACTURER      : NULL                               
REMARK 210                                                                      
REMARK 210  STRUCTURE DETERMINATION.                                            
REMARK 210   SOFTWARE USED                 : X-PLOR 3.851                       
REMARK 210   METHOD USED                   : SIMULATED ANNEALING                
REMARK 210                                                                      
REMARK 210 CONFORMERS, NUMBER CALCULATED   : 100                                
REMARK 210 CONFORMERS, NUMBER SUBMITTED    : 24                                 
REMARK 210 CONFORMERS, SELECTION CRITERIA  : LOW ENERGY AND AGREEMENT WITH      
REMARK 210                                   EXPERIMENTAL RESTRAINTS            
REMARK 210                                                                      
REMARK 210 BEST REPRESENTATIVE CONFORMER IN THIS ENSEMBLE : NULL                
REMARK 210                                                                      
REMARK 210 REMARK: THE STRUCTURE WAS DETERMINED USING NMR SPECTROSCOPY ON       
REMARK 210  UNIFORMLY 15N-LABELLED 1F1-2F1                                      
REMARK 215                                                                      
REMARK 215 NMR STUDY                                                            
REMARK 215 THE COORDINATES IN THIS ENTRY WERE GENERATED FROM SOLUTION           
REMARK 215 NMR DATA.  PROTEIN DATA BANK CONVENTIONS REQUIRE THAT                
REMARK 215 CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES ON              
REMARK 215 THESE RECORDS ARE MEANINGLESS.                                       
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: TORSION ANGLES                                             
REMARK 500                                                                      
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:            
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)                    
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-           
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400            
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        PSI       PHI                                   
REMARK 500  1 LYS A  18      131.26   -171.89                                   
REMARK 500  1 PRO A  19     -165.48    -74.19                                   
REMARK 500  1 ILE A  30      151.62    -36.47                                   
REMARK 500  1 LEU A  39      -48.42     82.89                                   
REMARK 500  1 ALA A  42      141.96    -36.53                                   
REMARK 500  1 LEU A  43       99.38   -169.92                                   
REMARK 500  1 LYS A  59      103.05    -36.55                                   
REMARK 500  1 GLU A  61       57.39   -157.45                                   
REMARK 500  1 ALA A  62      105.67     50.85                                   
REMARK 500  1 GLU A  64       63.05    159.37                                   
REMARK 500  1 THR A  65      154.54    170.66                                   
REMARK 500  1 CYS A  66     -154.55   -126.07                                   
REMARK 500  1 PHE A  67      -40.31   -158.30                                   
REMARK 500  1 ASP A  68       70.07     71.01                                   
REMARK 500  1 TYR A  81      110.70   -160.65                                   
REMARK 500  1 ASP A  86     -159.16     80.65                                   
REMARK 500  1 CYS A  94       69.65    -63.08                                   
REMARK 500  1 ILE A  95       46.89    -89.64                                   
REMARK 500  1 ALA A  97      -89.05     61.38                                   
REMARK 500  1 ARG A  99      -67.68   -174.87                                   
REMARK 500  1 ARG A 101       42.28   -109.25                                   
REMARK 500  1 ILE A 102       95.90    -52.55                                   
REMARK 500  2 LYS A  18       89.76     55.21                                   
REMARK 500  2 PRO A  19     -163.87    -56.24                                   
REMARK 500  2 ASN A  24      -75.67    -34.96                                   
REMARK 500  2 ALA A  42      147.57    -35.04                                   
REMARK 500  2 SER A  51       -0.56     85.78                                   
REMARK 500  2 LYS A  59      136.70    -39.55                                   
REMARK 500  2 PRO A  60     -169.10    -49.23                                   
REMARK 500  2 GLU A  64       57.03    -95.85                                   
REMARK 500  2 PHE A  67       97.94   -163.83                                   
REMARK 500  2 LYS A  69      -30.25    -39.41                                   
REMARK 500  2 ASP A  91       95.07    -66.88                                   
REMARK 500  2 CYS A  94       51.01    -96.80                                   
REMARK 500  2 ALA A  97       94.84     83.70                                   
REMARK 500  2 ARG A  99       34.59   -166.67                                   
REMARK 500  2 ARG A 101       56.77   -106.90                                   
REMARK 500  2 ALA A 107     -178.57     46.51                                   
REMARK 500  2 ASN A 108       40.78    -97.58                                   
REMARK 500  3 LYS A  18      145.76     58.32                                   
REMARK 500  3 ILE A  30      140.38    -35.00                                   
REMARK 500  3 ARG A  36     -163.91   -115.63                                   
REMARK 500  3 THR A  37       32.37   -167.08                                   
REMARK 500  3 ALA A  42      135.10    -31.01                                   
REMARK 500  3 PHE A  54      172.97    -59.70                                   
REMARK 500  3 GLU A  57      -94.06   -141.28                                   
REMARK 500  3 SER A  58      131.33    178.86                                   
REMARK 500  3 ALA A  62     -165.02   -161.50                                   
REMARK 500  3 GLU A  64     -172.65     72.77                                   
REMARK 500  3 THR A  65     -167.03     48.83                                   
REMARK 500  3 CYS A  66      177.80    167.23                                   
REMARK 500  3 LYS A  69      173.91    -51.87                                   
REMARK 500  3 TYR A  70      -54.58     76.19                                   
REMARK 500  3 ASP A  91       91.68    -58.58                                   
REMARK 500  3 CYS A  94       82.35    -53.85                                   
REMARK 500  3 ARG A  99      -46.14   -147.98                                   
REMARK 500  3 ARG A 101       94.30    172.02                                   
REMARK 500  3 ALA A 107      120.08     68.61                                   
REMARK 500  4 ASN A  31       18.02     53.78                                   
REMARK 500  4 ALA A  42      152.31    -37.75                                   
REMARK 500  4 LYS A  59      111.55    -39.88                                   
REMARK 500  4 THR A  65     -162.27     64.85                                   
REMARK 500  4 ASP A  68       93.56     35.52                                   
REMARK 500  4 LYS A  69     -170.13    -52.87                                   
REMARK 500  4 TYR A  70      -56.40     83.87                                   
REMARK 500  4 ASP A  86      -92.70     46.76                                   
REMARK 500  4 SER A  87       18.37   -152.16                                   
REMARK 500  4 ASP A  91       72.08    -67.10                                   
REMARK 500  4 CYS A  94       80.53    -58.53                                   
REMARK 500  4 ALA A  97       58.82    -69.23                                   
REMARK 500  4 ARG A  99       55.81   -176.58                                   
REMARK 500  4 ARG A 101       49.33   -178.58                                   
REMARK 500  4 ILE A 102       90.48    -38.39                                   
REMARK 500  4 ILE A 106      151.00    -43.99                                   
REMARK 500  5 PRO A  19     -169.08    -50.84                                   
REMARK 500  5 ALA A  42      156.64    -39.34                                   
REMARK 500  5 TYR A  48      -39.65   -133.36                                   
REMARK 500  5 ALA A  62     -168.96     42.21                                   
REMARK 500  5 THR A  65      177.97    175.37                                   
REMARK 500  5 CYS A  66     -162.34    175.11                                   
REMARK 500  5 PHE A  67      -38.73   -170.07                                   
REMARK 500  5 ASP A  68       88.11     49.98                                   
REMARK 500  5 THR A  71      -44.93   -162.86                                   
REMARK 500  5 VAL A  77       44.71     29.32                                   
REMARK 500  5 ASP A  79      109.06   -160.75                                   
REMARK 500  5 ASP A  86      -84.66     60.74                                   
REMARK 500  5 SER A  87       21.47   -155.81                                   
REMARK 500  5 CYS A  94       68.20    -69.95                                   
REMARK 500  5 ALA A  97       72.49     85.17                                   
REMARK 500  5 ARG A  99       56.96   -163.82                                   
REMARK 500  5 ARG A 101      115.89     55.15                                   
REMARK 500  5 ILE A 102       94.36    -44.98                                   
REMARK 500  6 PRO A  19     -162.92    -74.45                                   
REMARK 500  6 CYS A  21       52.41   -159.68                                   
REMARK 500  6 TYR A  22      102.78    -47.88                                   
REMARK 500  6 ASP A  23     -167.24    -77.95                                   
REMARK 500  6 ILE A  30      147.28    -37.83                                   
REMARK 500  6 ARG A  36     -169.95   -123.52                                   
REMARK 500  6 ALA A  42      147.59    -36.04                                   
REMARK 500  6 GLU A  57      171.93    178.36                                   
REMARK 500  6 GLU A  64       79.23   -106.06                                   
REMARK 500  6 CYS A  66      105.06    173.93                                   
REMARK 500  6 LYS A  69      -31.55    -36.08                                   
REMARK 500  6 ARG A  83      111.12   -164.98                                   
REMARK 500  6 LYS A  85      132.41   -171.77                                   
REMARK 500  6 ASP A  86     -160.36     54.71                                   
REMARK 500  6 SER A  87       33.71    -89.64                                   
REMARK 500  6 CYS A  94       86.20    -68.22                                   
REMARK 500  6 ILE A 102      102.55    -56.22                                   
REMARK 500  7 LYS A  18      147.53     63.81                                   
REMARK 500  7 ILE A  30      154.03    -49.47                                   
REMARK 500  7 ASN A  31       17.95     59.53                                   
REMARK 500  7 CYS A  56      146.16     72.39                                   
REMARK 500  7 GLU A  57      -89.94   -124.48                                   
REMARK 500  7 GLU A  61       57.48   -143.77                                   
REMARK 500  7 ALA A  62     -169.98     56.00                                   
REMARK 500  7 PHE A  67      118.59   -161.78                                   
REMARK 500  7 LYS A  69      -35.85    -35.18                                   
REMARK 500  7 THR A  71       32.33   -140.48                                   
REMARK 500  7 ARG A  76      178.71     49.15                                   
REMARK 500  7 ASP A  86     -153.70     81.85                                   
REMARK 500  7 ALA A  97       80.71     80.18                                   
REMARK 500  7 ARG A  99      -55.53   -139.73                                   
REMARK 500  7 ARG A 101      169.51    179.73                                   
REMARK 500  7 SER A 103      155.95    -45.42                                   
REMARK 500  7 ALA A 107     -163.90     43.64                                   
REMARK 500  8 CYS A  21       64.83   -158.07                                   
REMARK 500  8 ASP A  23      119.82   -162.99                                   
REMARK 500  8 ALA A  42      153.98    -37.50                                   
REMARK 500  8 SER A  51      -61.60   -149.40                                   
REMARK 500  8 PHE A  54      151.08     56.04                                   
REMARK 500  8 GLU A  57      166.76    172.31                                   
REMARK 500  8 GLU A  61       46.29     38.86                                   
REMARK 500  8 GLU A  64     -166.38    179.50                                   
REMARK 500  8 THR A  71       30.51   -159.77                                   
REMARK 500  8 CYS A  94       61.98    -65.89                                   
REMARK 500  8 ALA A  97      -74.35     67.47                                   
REMARK 500  8 ARG A 101      112.44     68.39                                   
REMARK 500  8 ILE A 102      151.53    -34.95                                   
REMARK 500  9 LYS A  18       71.19     38.35                                   
REMARK 500  9 LEU A  39       56.97     77.74                                   
REMARK 500  9 SER A  51      -13.29     85.06                                   
REMARK 500  9 CYS A  56      159.42     71.31                                   
REMARK 500  9 GLU A  57      -93.50   -141.65                                   
REMARK 500  9 GLU A  64       46.07   -169.46                                   
REMARK 500  9 PHE A  67       93.62   -178.61                                   
REMARK 500  9 ASP A  68       38.18    -93.98                                   
REMARK 500  9 LYS A  69     -159.73     36.60                                   
REMARK 500  9 TYR A  70      -54.71     73.32                                   
REMARK 500  9 ASP A  86     -156.53     72.84                                   
REMARK 500  9 ASP A  91       57.81    -93.15                                   
REMARK 500  9 CYS A  92      151.63    -38.21                                   
REMARK 500  9 CYS A  94       88.30    -64.66                                   
REMARK 500  9 ILE A  95       46.62   -101.80                                   
REMARK 500  9 ARG A  99       51.32    171.59                                   
REMARK 500  9 ARG A 101       38.89   -141.45                                   
REMARK 500  9 ILE A 102       89.25    -56.96                                   
REMARK 500 10 ILE A  30      156.23    -49.53                                   
REMARK 500 10 ASN A  31       19.65     56.86                                   
REMARK 500 10 SER A  51      -62.91    160.00                                   
REMARK 500 10 GLU A  57      -89.69   -152.75                                   
REMARK 500 10 SER A  58     -167.18   -164.49                                   
REMARK 500 10 LYS A  59      110.78   -164.47                                   
REMARK 500 10 PRO A  60     -163.10    -51.46                                   
REMARK 500 10 GLU A  61      -66.16   -121.30                                   
REMARK 500 10 GLU A  64     -169.02    -66.57                                   
REMARK 500 10 THR A  65     -177.56     48.01                                   
REMARK 500 10 CYS A  66     -156.33   -150.12                                   
REMARK 500 10 PHE A  67       81.77   -168.32                                   
REMARK 500 10 ASP A  68       87.08    -52.74                                   
REMARK 500 10 ASN A  73     -162.88   -122.37                                   
REMARK 500 10 ARG A  83       86.58   -167.66                                   
REMARK 500 10 PRO A  84       91.94    -69.13                                   
REMARK 500 10 ILE A  89      129.02     58.77                                   
REMARK 500 10 CYS A  94       73.14    -60.37                                   
REMARK 500 10 ALA A  97       53.32   -107.71                                   
REMARK 500 10 ARG A  99       40.83   -173.23                                   
REMARK 500 10 ARG A 101       51.33    171.33                                   
REMARK 500 10 ILE A 102       97.88    -37.11                                   
REMARK 500 10 ALA A 107      117.69   -173.53                                   
REMARK 500 11 ASN A  31       14.22     59.42                                   
REMARK 500 11 ALA A  42      147.77    -35.55                                   
REMARK 500 11 GLU A  57     -178.23   -176.23                                   
REMARK 500 11 PRO A  60       96.72    -51.60                                   
REMARK 500 11 GLU A  64     -166.89    -68.05                                   
REMARK 500 11 THR A  65     -175.34     46.45                                   
REMARK 500 11 PRO A  84       96.80    -49.93                                   
REMARK 500 11 ASP A  86     -155.37     53.20                                   
REMARK 500 11 SER A  87       43.96    -89.20                                   
REMARK 500 11 MET A  88      126.16   -175.67                                   
REMARK 500 11 ASP A  91       87.85    -60.58                                   
REMARK 500 11 ALA A  97       85.28    -49.29                                   
REMARK 500 11 ARG A  99      107.91     83.29                                   
REMARK 500 11 ARG A 101       38.58   -146.02                                   
REMARK 500 11 ILE A 102       90.69    -47.59                                   
REMARK 500 11 ILE A 106       94.34    -66.48                                   
REMARK 500 11 ASN A 108       68.16   -175.40                                   
REMARK 500 12 LYS A  18       97.51    -38.26                                   
REMARK 500 12 ASP A  23     -160.95   -126.98                                   
REMARK 500 12 ALA A  42      151.29    -43.75                                   
REMARK 500 12 TYR A  48      -43.99   -138.62                                   
REMARK 500 12 GLU A  57      178.78    171.99                                   
REMARK 500 12 SER A  58      173.42    -59.36                                   
REMARK 500 12 PRO A  60       98.33    -55.89                                   
REMARK 500 12 GLU A  61       65.69   -117.41                                   
REMARK 500 12 ALA A  62     -169.15     42.13                                   
REMARK 500 12 CYS A  66      171.65    175.86                                   
REMARK 500 12 PHE A  67       94.00   -179.28                                   
REMARK 500 12 ASP A  68       81.65    -69.02                                   
REMARK 500 12 THR A  71      -54.47   -137.70                                   
REMARK 500 12 TYR A  75     -160.51   -105.79                                   
REMARK 500 12 PRO A  84      152.34    -46.50                                   
REMARK 500 12 ASP A  91       80.99    -68.36                                   
REMARK 500 12 CYS A  92      178.79    -54.85                                   
REMARK 500 12 ALA A  97       61.26   -159.59                                   
REMARK 500 12 ARG A  99       45.56    161.24                                   
REMARK 500 12 ARG A 101      105.70     48.56                                   
REMARK 500 12 ILE A 102      130.82    -36.92                                   
REMARK 500 12 ILE A 106      151.06    -44.15                                   
REMARK 500 13 LYS A  18      141.04    176.35                                   
REMARK 500 13 PRO A  19     -163.23    -68.38                                   
REMARK 500 13 THR A  37      -51.77   -151.20                                   
REMARK 500 13 TYR A  38      104.97     44.86                                   
REMARK 500 13 LEU A  39       15.56     82.77                                   
REMARK 500 13 ALA A  42      119.43    -32.96                                   
REMARK 500 13 GLU A  57      135.58   -171.32                                   
REMARK 500 13 ALA A  62      169.21     51.29                                   
REMARK 500 13 THR A  65     -177.84     46.14                                   
REMARK 500 13 THR A  71      -47.96   -142.45                                   
REMARK 500 13 LYS A  85      158.73    178.45                                   
REMARK 500 13 ASP A  86      -89.71     59.28                                   
REMARK 500 13 SER A  87       25.37   -156.34                                   
REMARK 500 13 CYS A  94       77.63    -58.38                                   
REMARK 500 13 ALA A  97       43.76   -163.27                                   
REMARK 500 13 ARG A  99       38.05   -167.77                                   
REMARK 500 13 ARG A 101      109.67    168.49                                   
REMARK 500 13 ILE A 102       74.64    -69.69                                   
REMARK 500 13 SER A 103      156.56    -41.99                                   
REMARK 500 14 ASN A  24       28.79     44.81                                   
REMARK 500 14 ILE A  30      150.81    -48.91                                   
REMARK 500 14 ASN A  31       17.24     59.84                                   
REMARK 500 14 LEU A  39      -49.24     82.36                                   
REMARK 500 14 ALA A  42      150.94    -36.16                                   
REMARK 500 14 SER A  51      -64.29   -173.02                                   
REMARK 500 14 GLU A  57     -171.57    177.52                                   
REMARK 500 14 GLU A  64      176.40    171.49                                   
REMARK 500 14 THR A  65     -177.65     60.86                                   
REMARK 500 14 CYS A  66      129.17    176.20                                   
REMARK 500 14 LYS A  69      164.46    -39.81                                   
REMARK 500 14 TYR A  70      -46.31     83.95                                   
REMARK 500 14 GLU A  82      165.75     76.44                                   
REMARK 500 14 ARG A  83      107.57   -172.39                                   
REMARK 500 14 PRO A  84       89.60    -68.94                                   
REMARK 500 14 ILE A  89      122.29     59.31                                   
REMARK 500 14 ASP A  91       79.79    -57.77                                   
REMARK 500 14 CYS A  94       80.11    -57.83                                   
REMARK 500 14 ALA A  97       57.92    -96.94                                   
REMARK 500 14 ARG A  99       38.88    162.21                                   
REMARK 500 14 ARG A 101       94.91   -176.12                                   
REMARK 500 14 ILE A 102       99.43    -58.59                                   
REMARK 500 14 THR A 105      149.45   -178.27                                   
REMARK 500 14 ASN A 108       59.29    179.49                                   
REMARK 500 15 LYS A  18       67.67   -151.34                                   
REMARK 500 15 PRO A  19     -158.13    -61.33                                   
REMARK 500 15 ASP A  23      131.85   -178.30                                   
REMARK 500 15 ALA A  42      152.25    -37.08                                   
REMARK 500 15 PHE A  54     -172.03    -58.17                                   
REMARK 500 15 GLU A  57      -92.29   -171.95                                   
REMARK 500 15 SER A  58     -177.16    175.81                                   
REMARK 500 15 PRO A  60      177.49    -49.01                                   
REMARK 500 15 GLU A  64       39.54   -177.29                                   
REMARK 500 15 CYS A  66      -63.66   -157.02                                   
REMARK 500 15 PHE A  67       92.25     79.76                                   
REMARK 500 15 ASP A  68       44.40    -88.69                                   
REMARK 500 15 LYS A  69     -144.52     36.16                                   
REMARK 500 15 TYR A  70      -50.33     79.95                                   
REMARK 500 15 THR A  71      -35.88   -171.37                                   
REMARK 500 15 ASN A  73       49.53   -104.44                                   
REMARK 500 15 ASP A  86      -35.18     87.86                                   
REMARK 500 15 SER A  87      -23.33    159.02                                   
REMARK 500 15 CYS A  94       77.87    -61.59                                   
REMARK 500 15 ARG A  99       44.65    178.99                                   
REMARK 500 15 ARG A 101       62.79   -177.70                                   
REMARK 500 15 ILE A 102       91.94    -36.15                                   
REMARK 500 15 ASN A 108       82.10    -69.02                                   
REMARK 500 16 ILE A  30      148.22    -33.99                                   
REMARK 500 16 TYR A  38      115.26    177.02                                   
REMARK 500 16 LEU A  39       34.43     74.66                                   
REMARK 500 16 GLU A  57      -70.13   -137.65                                   
REMARK 500 16 PRO A  60      104.26    -52.15                                   
REMARK 500 16 GLU A  61      -74.27    -38.26                                   
REMARK 500 16 GLU A  64       78.59    -62.33                                   
REMARK 500 16 PHE A  67      100.94   -168.73                                   
REMARK 500 16 LYS A  69     -165.76     39.07                                   
REMARK 500 16 TYR A  70      -54.62     74.56                                   
REMARK 500 16 ASP A  86     -167.54     80.31                                   
REMARK 500 16 MET A  88      -60.97   -145.52                                   
REMARK 500 16 ILE A  89      130.47     62.45                                   
REMARK 500 16 CYS A  94       40.27   -108.99                                   
REMARK 500 16 ARG A  99      132.22     64.80                                   
REMARK 500 16 ARG A 101       43.12   -102.52                                   
REMARK 500 16 ILE A 102       95.47    -54.41                                   
REMARK 500 16 ALA A 107      117.79    171.60                                   
REMARK 500 16 ASN A 108      116.47   -163.68                                   
REMARK 500 17 LYS A  18       65.73   -150.62                                   
REMARK 500 17 ILE A  30      138.91    -33.86                                   
REMARK 500 17 PHE A  54     -167.80    -59.28                                   
REMARK 500 17 ASN A  55      -49.95   -147.16                                   
REMARK 500 17 CYS A  56     -172.64     85.62                                   
REMARK 500 17 GLU A  57      -89.23   -156.78                                   
REMARK 500 17 SER A  58      146.44    170.97                                   
REMARK 500 17 LYS A  59      116.30    -39.83                                   
REMARK 500 17 PRO A  60     -177.89    -60.89                                   
REMARK 500 17 THR A  65     -176.63    -57.95                                   
REMARK 500 17 ASP A  68       85.96    -58.95                                   
REMARK 500 17 TYR A  70      -72.74    -40.02                                   
REMARK 500 17 ASN A  73     -162.90   -108.41                                   
REMARK 500 17 PRO A  84       84.37    -69.78                                   
REMARK 500 17 ASP A  86     -157.89     46.32                                   
REMARK 500 17 MET A  88      149.60    174.44                                   
REMARK 500 17 CYS A  94       60.21    -66.29                                   
REMARK 500 17 ILE A  95       80.17    -68.77                                   
REMARK 500 17 ALA A  97       79.79     55.09                                   
REMARK 500 17 ARG A  99       63.23   -179.12                                   
REMARK 500 17 ARG A 101      104.24     66.80                                   
REMARK 500 17 ILE A 102      128.36    -36.32                                   
REMARK 500 17 ILE A 106       87.67    -58.79                                   
REMARK 500 18 LYS A  18       83.51     60.30                                   
REMARK 500 18 LEU A  39       22.62     80.91                                   
REMARK 500 18 ALA A  42      153.92    -35.69                                   
REMARK 500 18 SER A  51      -10.01     83.88                                   
REMARK 500 18 GLU A  57     -177.62   -175.02                                   
REMARK 500 18 GLU A  61      -41.46    162.44                                   
REMARK 500 18 THR A  65     -171.82    175.59                                   
REMARK 500 18 ASP A  68       84.04     71.80                                   
REMARK 500 18 LYS A  69     -170.61    -57.53                                   
REMARK 500 18 TYR A  70       -4.20     84.40                                   
REMARK 500 18 THR A  71      -26.22    165.26                                   
REMARK 500 18 THR A  80     -155.41    -96.72                                   
REMARK 500 18 TYR A  81      -35.13   -172.02                                   
REMARK 500 18 GLU A  82      157.60     87.29                                   
REMARK 500 18 ARG A  83      119.01    178.44                                   
REMARK 500 18 ASP A  86      -85.04     56.80                                   
REMARK 500 18 SER A  87       23.18   -159.71                                   
REMARK 500 18 CYS A  94       87.62    -54.41                                   
REMARK 500 18 ARG A 101       54.83    -99.18                                   
REMARK 500 18 ILE A 102      126.71    -37.30                                   
REMARK 500 19 PRO A  19     -176.07    -48.46                                   
REMARK 500 19 ASP A  23     -159.99   -133.86                                   
REMARK 500 19 TYR A  28     -168.96    -79.62                                   
REMARK 500 19 TYR A  38      137.06   -178.42                                   
REMARK 500 19 GLU A  57      -86.08   -136.01                                   
REMARK 500 19 SER A  58     -166.05   -170.01                                   
REMARK 500 19 PRO A  60       99.58    -49.85                                   
REMARK 500 19 PHE A  67      110.13   -165.21                                   
REMARK 500 19 LYS A  69     -154.13     34.22                                   
REMARK 500 19 TYR A  70      -54.22     75.29                                   
REMARK 500 19 THR A  71      -62.43   -138.47                                   
REMARK 500 19 THR A  74      107.88    -45.87                                   
REMARK 500 19 TYR A  75     -157.98    -85.47                                   
REMARK 500 19 CYS A  94       69.84    -67.62                                   
REMARK 500 19 ALA A  97      -41.29   -140.30                                   
REMARK 500 19 ARG A  99       36.97    170.80                                   
REMARK 500 19 ARG A 101       75.17    170.55                                   
REMARK 500 19 ILE A 102       79.55    -58.14                                   
REMARK 500 20 ASN A  31       17.69     55.01                                   
REMARK 500 20 TRP A  34     -167.41   -165.75                                   
REMARK 500 20 CYS A  56      148.29     59.27                                   
REMARK 500 20 GLU A  57      -88.90   -130.08                                   
REMARK 500 20 PRO A  60       72.23    -57.56                                   
REMARK 500 20 THR A  65     -160.11   -178.31                                   
REMARK 500 20 CYS A  66     -178.00   -175.63                                   
REMARK 500 20 PRO A  84       85.93    -53.81                                   
REMARK 500 20 ASP A  86      -92.02     45.37                                   
REMARK 500 20 SER A  87       20.65   -143.83                                   
REMARK 500 20 ASP A  91       63.61    -65.59                                   
REMARK 500 20 CYS A  92       93.38    -51.13                                   
REMARK 500 20 ARG A  99      -60.55   -164.86                                   
REMARK 500 21 SER A  51      -58.90   -156.04                                   
REMARK 500 21 PHE A  54       99.03    -56.47                                   
REMARK 500 21 GLU A  57     -174.17   -171.03                                   
REMARK 500 21 LYS A  59      107.85    -36.69                                   
REMARK 500 21 PRO A  60     -176.64    -48.68                                   
REMARK 500 21 ALA A  62       97.93    -46.85                                   
REMARK 500 21 CYS A  66      -66.07    177.53                                   
REMARK 500 21 PHE A  67       74.82     63.28                                   
REMARK 500 21 ASP A  68       95.19    -41.27                                   
REMARK 500 21 THR A  74       79.06   -111.03                                   
REMARK 500 21 PRO A  84       88.35    -64.62                                   
REMARK 500 21 ASP A  86      177.42     67.92                                   
REMARK 500 21 MET A  88      -47.41   -150.23                                   
REMARK 500 21 ILE A  89      137.40     62.76                                   
REMARK 500 21 CYS A  92       99.19    -52.34                                   
REMARK 500 21 ASN A 108      145.10   -175.54                                   
REMARK 500 22 PRO A  19     -165.33    -57.10                                   
REMARK 500 22 TYR A  22      119.35    174.93                                   
REMARK 500 22 ASN A  24       27.47     48.35                                   
REMARK 500 22 TYR A  48      -47.08   -130.37                                   
REMARK 500 22 LYS A  59       97.08     38.69                                   
REMARK 500 22 PRO A  60     -167.31    -69.24                                   
REMARK 500 22 THR A  65     -172.01   -173.91                                   
REMARK 500 22 PHE A  67      106.74   -160.60                                   
REMARK 500 22 ASP A  86     -155.18     77.31                                   
REMARK 500 22 CYS A  92       99.95    -47.90                                   
REMARK 500 22 CYS A  94       86.47    -63.76                                   
REMARK 500 22 ALA A  97     -157.46     79.76                                   
REMARK 500 22 ARG A  99      -55.03   -155.69                                   
REMARK 500 22 ARG A 101       87.07     69.11                                   
REMARK 500 22 ILE A 106      155.24    -47.91                                   
REMARK 500 23 LYS A  18       67.65     36.82                                   
REMARK 500 23 ILE A  30      139.07    -31.85                                   
REMARK 500 23 SER A  51      -51.73    159.66                                   
REMARK 500 23 SER A  58      161.01    -37.30                                   
REMARK 500 23 GLU A  64      114.37     66.26                                   
REMARK 500 23 THR A  65      169.33    171.82                                   
REMARK 500 23 LYS A  69      176.07    -45.44                                   
REMARK 500 23 THR A  71      -34.47   -177.75                                   
REMARK 500 23 TYR A  81      134.92   -174.29                                   
REMARK 500 23 PRO A  84       74.10    -66.20                                   
REMARK 500 23 ASP A  86     -173.85     57.23                                   
REMARK 500 23 MET A  88      166.93    176.48                                   
REMARK 500 23 ALA A  97       45.32    -89.27                                   
REMARK 500 23 ARG A  99      -40.84    173.60                                   
REMARK 500 23 ARG A 101       33.68   -179.03                                   
REMARK 500 23 ILE A 102       89.26     28.55                                   
REMARK 500 24 LYS A  18       96.35   -176.24                                   
REMARK 500 24 TYR A  22      143.98    177.61                                   
REMARK 500 24 ASP A  23      169.70    166.66                                   
REMARK 500 24 SER A  58      130.52    -37.43                                   
REMARK 500 24 LYS A  59      118.68    -39.09                                   
REMARK 500 24 GLU A  64       82.57    -64.34                                   
REMARK 500 24 ASP A  68       86.83    -53.65                                   
REMARK 500 24 TYR A  70      -74.94    -36.59                                   
REMARK 500 24 ARG A  83      121.96    169.95                                   
REMARK 500 24 LYS A  85      161.98    173.86                                   
REMARK 500 24 ASP A  86       19.97     56.81                                   
REMARK 500 24 SER A  87       18.61     82.16                                   
REMARK 500 24 ASP A  91       92.23    -38.88                                   
REMARK 500 24 CYS A  94       88.67    -59.60                                   
REMARK 500 24 ARG A  99      -83.29    176.49                                   
REMARK 500 24 ARG A 101      104.59    176.95                                   
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
DBREF  1QGB A   17   109  UNP    P02751   FINC_HUMAN      48    140             
SEQRES   1 A   93  SER LYS PRO GLY CYS TYR ASP ASN GLY LYS HIS TYR GLN          
SEQRES   2 A   93  ILE ASN GLN GLN TRP GLU ARG THR TYR LEU GLY ASN ALA          
SEQRES   3 A   93  LEU VAL CYS THR CYS TYR GLY GLY SER ARG GLY PHE ASN          
SEQRES   4 A   93  CYS GLU SER LYS PRO GLU ALA GLU GLU THR CYS PHE ASP          
SEQRES   5 A   93  LYS TYR THR GLY ASN THR TYR ARG VAL GLY ASP THR TYR          
SEQRES   6 A   93  GLU ARG PRO LYS ASP SER MET ILE TRP ASP CYS THR CYS          
SEQRES   7 A   93  ILE GLY ALA GLY ARG GLY ARG ILE SER CYS THR ILE ALA          
SEQRES   8 A   93  ASN ARG                                                      
SHEET    1   A 2 CYS A  21  ASP A  23  0                                        
SHEET    2   A 2 LYS A  26  TYR A  28 -1  N  LYS A  26   O  ASP A  23           
SHEET    1   B 2 GLN A  33  THR A  37  0                                        
SHEET    2   B 2 ALA A  42  THR A  46 -1  O  LEU A  43   N  ARG A  36           
SHEET    1   C 2 TRP A  90  THR A  93  0                                        
SHEET    2   C 2 SER A 103  ILE A 106 -1  O  SER A 103   N  THR A  93           
SSBOND   1 CYS A   21    CYS A   47                          1555   1555  2.03  
SSBOND   2 CYS A   45    CYS A   56                          1555   1555  2.03  
SSBOND   3 CYS A   66    CYS A   94                          1555   1555  2.03  
SSBOND   4 CYS A   92    CYS A  104                          1555   1555  2.03  
CRYST1    1.000    1.000    1.000  90.00  90.00  90.00 P 1           1          
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      1.000000  0.000000  0.000000        0.00000                         
SCALE2      0.000000  1.000000  0.000000        0.00000                         
SCALE3      0.000000  0.000000  1.000000        0.00000                         
MODEL        1                                                                  
(ATOM LINES ARE NOT SHOWN.)
END                                                                             
DBGET integrated database retrieval system