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Database: PDB
Entry: 1V27
LinkDB: 1V27
Original site: 1V27 
HEADER    ENDOCYTOSIS/EXOCYTOSIS                  07-OCT-03   1V27              
TITLE     SOLUTION STRUCTURE OF THE FIRST C2 DOMAIN OF RIM2                     
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN            
COMPND   3 2;                                                                   
COMPND   4 CHAIN: A;                                                            
COMPND   5 FRAGMENT: C2 DOMAIN;                                                 
COMPND   6 SYNONYM: RAB3-INTERACTING MOLECULE 2, RIM2;                          
COMPND   7 ENGINEERED: YES                                                      
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE   3 ORGANISM_COMMON: HUMAN;                                              
SOURCE   4 ORGANISM_TAXID: 9606;                                                
SOURCE   5 GENE: KAZUSA CDNA KIAA0751;                                          
SOURCE   6 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                              
SOURCE   7 EXPRESSION_SYSTEM_PLASMID: P020930-02;                               
SOURCE   8 OTHER_DETAILS: CELL-FREE PROTEIN SYNTHESIS                           
KEYWDS    C2, EXOCYTOSIS, RAB3-INTERACTING MOLECULE, RIKEN STRUCTURAL           
KEYWDS   2 GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS,           
KEYWDS   3 ENDOCYTOSIS/EXOCYTOSIS COMPLEX                                       
EXPDTA    SOLUTION NMR                                                          
NUMMDL    20                                                                    
AUTHOR    T.NAGASHIMA,F.HAYASHI,S.YOKOYAMA,RIKEN STRUCTURAL                     
AUTHOR   2 GENOMICS/PROTEOMICS INITIATIVE (RSGI)                                
REVDAT   2   24-FEB-09 1V27    1       VERSN                                    
REVDAT   1   07-APR-04 1V27    0                                                
JRNL        AUTH   T.NAGASHIMA,F.HAYASHI,S.YOKOYAMA                             
JRNL        TITL   SOLUTION STRUCTURE OF THE FIRST C2 DOMAIN OF RIM2            
JRNL        REF    TO BE PUBLISHED                                              
JRNL        REFN                                                                
REMARK   1                                                                      
REMARK   2                                                                      
REMARK   2 RESOLUTION. NOT APPLICABLE.                                          
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   PROGRAM     : CYANA 1.0.7                                          
REMARK   3   AUTHORS     : GUENTERT, P.                                         
REMARK   3                                                                      
REMARK   3  OTHER REFINEMENT REMARKS: NULL                                      
REMARK   4                                                                      
REMARK   4 1V27 COMPLIES WITH FORMAT V. 3.15, 01-DEC-08                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBJ ON 10-OCT-03.                  
REMARK 100 THE RCSB ID CODE IS RCSB006113.                                      
REMARK 210                                                                      
REMARK 210 EXPERIMENTAL DETAILS                                                 
REMARK 210  EXPERIMENT TYPE                : NMR                                
REMARK 210  TEMPERATURE           (KELVIN) : 298                                
REMARK 210  PH                             : 7.0                                
REMARK 210  IONIC STRENGTH                 : 120MM                              
REMARK 210  PRESSURE                       : AMBIENT                            
REMARK 210  SAMPLE CONTENTS                : 1.1MM 13C/15N-LABELED              
REMARK 210                                   PROTEIN; 20MM TRIS-D11, 100MM      
REMARK 210                                   NACL, 0.02% NAN3                   
REMARK 210                                                                      
REMARK 210  NMR EXPERIMENTS CONDUCTED      : 3D_13C-SEPARATED_NOESY, 3D_        
REMARK 210                                   15N-SEPARATED_NOESY                
REMARK 210  SPECTROMETER FIELD STRENGTH    : 800 MHZ                            
REMARK 210  SPECTROMETER MODEL             : INOVA                              
REMARK 210  SPECTROMETER MANUFACTURER      : VARIAN                             
REMARK 210                                                                      
REMARK 210  STRUCTURE DETERMINATION.                                            
REMARK 210   SOFTWARE USED                 : VNMR 6.1C, NMRPIPE 20020425,       
REMARK 210                                   NMRVIEW 5.0.4, KUJIRA 0.861,       
REMARK 210                                   CYANA 1.0.7                        
REMARK 210   METHOD USED                   : TORSION ANGLE DYNAMICS             
REMARK 210                                                                      
REMARK 210 CONFORMERS, NUMBER CALCULATED   : 100                                
REMARK 210 CONFORMERS, NUMBER SUBMITTED    : 20                                 
REMARK 210 CONFORMERS, SELECTION CRITERIA  : STRUCTURES WITH THE LEAST          
REMARK 210                                   RESTRAINT VIOLATIONS, TARGET       
REMARK 210                                   FUNCTION                           
REMARK 210                                                                      
REMARK 210 BEST REPRESENTATIVE CONFORMER IN THIS ENSEMBLE : 1                   
REMARK 210                                                                      
REMARK 210 REMARK: NULL                                                         
REMARK 215                                                                      
REMARK 215 NMR STUDY                                                            
REMARK 215 THE COORDINATES IN THIS ENTRY WERE GENERATED FROM SOLUTION           
REMARK 215 NMR DATA.  PROTEIN DATA BANK CONVENTIONS REQUIRE THAT                
REMARK 215 CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES ON              
REMARK 215 THESE RECORDS ARE MEANINGLESS.                                       
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: TORSION ANGLES                                             
REMARK 500                                                                      
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:            
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)                    
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-           
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400            
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        PSI       PHI                                   
REMARK 500  1 SER A   2       92.04     64.44                                   
REMARK 500  1 VAL A  19      -72.73    -55.14                                   
REMARK 500  1 LEU A  28      -99.95    -55.41                                   
REMARK 500  1 SER A  35     -168.32   -108.31                                   
REMARK 500  1 GLU A  37      -88.28    -96.90                                   
REMARK 500  1 ASP A  38       56.89   -106.96                                   
REMARK 500  1 PRO A  41     -162.07    -75.06                                   
REMARK 500  1 PRO A  52     -169.44    -75.00                                   
REMARK 500  1 ASP A  53      128.75     78.98                                   
REMARK 500  1 SER A  55      -51.12   -161.69                                   
REMARK 500  1 ASP A  56     -160.75   -179.67                                   
REMARK 500  1 LYS A  57      -82.68     76.79                                   
REMARK 500  1 ASN A  58       36.97    -94.70                                   
REMARK 500  1 LYS A  67       89.36     41.05                                   
REMARK 500  1 THR A  68      111.23   -178.08                                   
REMARK 500  1 ASN A  74       36.84     38.47                                   
REMARK 500  1 ALA A 100      -82.84    -67.34                                   
REMARK 500  1 ARG A 101      177.17    -57.48                                   
REMARK 500  1 PHE A 109      111.13     55.54                                   
REMARK 500  1 ASP A 123       23.73   -151.98                                   
REMARK 500  1 ASP A 135      152.36    -49.41                                   
REMARK 500  1 SER A 136      110.68     66.69                                   
REMARK 500  1 SER A 139      127.57   -179.42                                   
REMARK 500  2 SER A   3       93.95   -170.43                                   
REMARK 500  2 SER A   5      132.62    179.53                                   
REMARK 500  2 VAL A  19      -71.92    -51.66                                   
REMARK 500  2 LEU A  28      -98.87    -58.10                                   
REMARK 500  2 ARG A  36       77.41   -111.47                                   
REMARK 500  2 GLU A  37      174.44     52.16                                   
REMARK 500  2 PRO A  41     -162.33    -74.98                                   
REMARK 500  2 PHE A  50       96.41    -68.30                                   
REMARK 500  2 ASP A  53      166.60     60.24                                   
REMARK 500  2 ARG A  54       94.88   -160.67                                   
REMARK 500  2 LYS A  67       87.47     50.78                                   
REMARK 500  2 THR A  68      113.28   -177.69                                   
REMARK 500  2 ASN A  74       37.03     38.31                                   
REMARK 500  2 GLN A  99       82.83    -69.43                                   
REMARK 500  2 ARG A 101      163.31     57.10                                   
REMARK 500  2 ARG A 103       58.95   -110.29                                   
REMARK 500  2 GLU A 106       64.74     38.84                                   
REMARK 500  2 PHE A 109      102.63     51.51                                   
REMARK 500  2 LEU A 121       93.33    -67.84                                   
REMARK 500  2 ASP A 123       26.00   -158.17                                   
REMARK 500  2 HIS A 134      131.48   -175.70                                   
REMARK 500  2 SER A 136      149.58   -171.89                                   
REMARK 500  2 SER A 140      105.57     59.11                                   
REMARK 500  3 SER A   2      163.17    -46.56                                   
REMARK 500  3 SER A   3      -49.33   -165.16                                   
REMARK 500  3 SER A   6      135.80   -176.99                                   
REMARK 500  3 VAL A  19      -71.01    -54.92                                   
REMARK 500  3 VAL A  25       97.82   -160.51                                   
REMARK 500  3 LEU A  28      -99.84    -56.35                                   
REMARK 500  3 ASP A  32       73.22     59.03                                   
REMARK 500  3 ARG A  36      -15.65     83.88                                   
REMARK 500  3 GLU A  37      176.27     50.98                                   
REMARK 500  3 ASP A  38      -49.47     82.63                                   
REMARK 500  3 TYR A  45      124.98   -177.50                                   
REMARK 500  3 PHE A  50       89.67    -68.56                                   
REMARK 500  3 ASP A  56      173.60    -47.79                                   
REMARK 500  3 LYS A  57      -62.54     81.84                                   
REMARK 500  3 LYS A  67       85.89     47.66                                   
REMARK 500  3 THR A  68      114.46   -178.78                                   
REMARK 500  3 ARG A 101     -176.44     48.75                                   
REMARK 500  3 ARG A 103      -79.35   -110.61                                   
REMARK 500  3 ASP A 123       34.08   -173.18                                   
REMARK 500  3 ASP A 124       48.39     39.12                                   
REMARK 500  3 ASP A 135       95.15   -170.16                                   
REMARK 500  3 SER A 136      159.20    -41.82                                   
REMARK 500  3 SER A 139      106.23   -178.21                                   
REMARK 500  3 SER A 140      111.12     61.46                                   
REMARK 500  4 SER A   2      116.55   -163.46                                   
REMARK 500  4 SER A   5       81.69   -164.93                                   
REMARK 500  4 SER A   6       85.34     43.40                                   
REMARK 500  4 LEU A  28     -100.05    -55.15                                   
REMARK 500  4 ARG A  36      136.86     61.58                                   
REMARK 500  4 GLU A  37      -68.65    178.46                                   
REMARK 500  4 PRO A  41      -90.64    -74.96                                   
REMARK 500  4 ARG A  42      154.31    166.20                                   
REMARK 500  4 TYR A  45      120.89   -175.68                                   
REMARK 500  4 ASP A  53       98.98    153.21                                   
REMARK 500  4 ASP A  56     -178.14    -54.05                                   
REMARK 500  4 LYS A  57      -77.73     86.52                                   
REMARK 500  4 LYS A  67       73.09     59.87                                   
REMARK 500  4 THR A  68      114.86   -176.80                                   
REMARK 500  4 ASN A  74       34.78     36.97                                   
REMARK 500  4 GLN A  99      106.05    -49.98                                   
REMARK 500  4 ARG A 101     -162.97     43.50                                   
REMARK 500  4 GLU A 104       93.74     51.36                                   
REMARK 500  4 GLU A 105      -60.27   -127.40                                   
REMARK 500  4 LEU A 121       87.72    -64.78                                   
REMARK 500  4 ASP A 123       26.76   -157.97                                   
REMARK 500  4 SER A 136      117.50   -179.21                                   
REMARK 500  5 SER A   5       78.91   -152.11                                   
REMARK 500  5 SER A   6      100.97   -168.14                                   
REMARK 500  5 LEU A  28      -99.24    -52.10                                   
REMARK 500  5 ARG A  36     -174.47     53.22                                   
REMARK 500  5 GLU A  37      -73.42     88.07                                   
REMARK 500  5 PRO A  41      -95.92    -75.01                                   
REMARK 500  5 ARG A  42     -179.08    158.77                                   
REMARK 500  5 PHE A  50       92.94    -67.31                                   
REMARK 500  5 ASP A  53      168.74    174.80                                   
REMARK 500  5 ARG A  54       72.65    160.02                                   
REMARK 500  5 SER A  55      -48.93   -173.10                                   
REMARK 500  5 ASP A  56     -175.71    172.27                                   
REMARK 500  5 LYS A  57      -76.06     82.69                                   
REMARK 500  5 LYS A  67       97.69     50.19                                   
REMARK 500  5 THR A  68      110.25   -177.99                                   
REMARK 500  5 ALA A 100      -67.20   -131.39                                   
REMARK 500  5 ARG A 101      178.89     63.36                                   
REMARK 500  5 VAL A 102     -175.23     47.66                                   
REMARK 500  5 ARG A 103      -93.31     52.69                                   
REMARK 500  5 GLU A 105       72.46     37.43                                   
REMARK 500  5 PHE A 109      114.06     56.20                                   
REMARK 500  5 ASP A 123       36.50   -177.07                                   
REMARK 500  5 ASP A 124       33.34     39.25                                   
REMARK 500  5 HIS A 134       98.97     50.93                                   
REMARK 500  5 ASP A 135      123.70   -177.03                                   
REMARK 500  6 SER A   2      155.91     63.90                                   
REMARK 500  6 SER A   3      129.16   -177.83                                   
REMARK 500  6 VAL A  19      -74.04    -52.92                                   
REMARK 500  6 LEU A  28     -100.28    -56.69                                   
REMARK 500  6 SER A  35     -167.04    -59.38                                   
REMARK 500  6 ARG A  40      158.13    -40.25                                   
REMARK 500  6 PRO A  41     -160.63    -74.94                                   
REMARK 500  6 ASP A  53      109.43    -40.23                                   
REMARK 500  6 SER A  55      -46.18   -172.74                                   
REMARK 500  6 ASP A  56     -156.91   -179.39                                   
REMARK 500  6 LYS A  57      -81.39     67.37                                   
REMARK 500  6 ASN A  58       44.46    -94.09                                   
REMARK 500  6 LYS A  67       90.98     44.22                                   
REMARK 500  6 THR A  68      111.97   -179.16                                   
REMARK 500  6 ASN A  74       36.48     38.31                                   
REMARK 500  6 GLN A  99       81.16    -63.19                                   
REMARK 500  6 ARG A 101      135.55     61.11                                   
REMARK 500  6 GLU A 104      147.47    179.90                                   
REMARK 500  6 PHE A 109       93.51     39.22                                   
REMARK 500  6 ASP A 123       31.60   -161.78                                   
REMARK 500  6 ASP A 124       27.68     47.34                                   
REMARK 500  6 ASP A 135      106.36     58.52                                   
REMARK 500  6 SER A 139      -58.57   -132.58                                   
REMARK 500  7 SER A   2      152.82    177.18                                   
REMARK 500  7 SER A   3      165.00     57.89                                   
REMARK 500  7 SER A   5       80.64   -170.12                                   
REMARK 500  7 VAL A  19      -72.50    -55.56                                   
REMARK 500  7 LEU A  28     -100.85    -59.05                                   
REMARK 500  7 SER A  35     -151.62     37.24                                   
REMARK 500  7 ARG A  36      151.82     59.02                                   
REMARK 500  7 GLU A  37      -77.09    174.93                                   
REMARK 500  7 PRO A  41      -94.56    -74.97                                   
REMARK 500  7 ARG A  42      177.86    156.81                                   
REMARK 500  7 PHE A  50       87.13    -66.25                                   
REMARK 500  7 ARG A  54       91.56   -168.59                                   
REMARK 500  7 SER A  55      -48.75   -174.06                                   
REMARK 500  7 ASP A  56     -170.45    176.40                                   
REMARK 500  7 LYS A  57      -68.88     68.91                                   
REMARK 500  7 LYS A  67       93.68     44.33                                   
REMARK 500  7 THR A  68      117.67   -176.47                                   
REMARK 500  7 ASN A  74       36.14     38.02                                   
REMARK 500  7 ARG A 101     -178.50     52.17                                   
REMARK 500  7 ARG A 103      -66.31   -135.50                                   
REMARK 500  7 ASP A 123       38.78    177.85                                   
REMARK 500  7 HIS A 134       83.93     67.20                                   
REMARK 500  7 ASP A 135      -44.37   -165.42                                   
REMARK 500  7 SER A 136      -81.29     64.74                                   
REMARK 500  8 SER A   2      -51.83   -156.22                                   
REMARK 500  8 SER A   6       68.16   -175.73                                   
REMARK 500  8 LEU A  28      -99.46    -64.79                                   
REMARK 500  8 GLU A  37     -171.43     62.13                                   
REMARK 500  8 PRO A  41     -162.47    -75.00                                   
REMARK 500  8 TYR A  45      135.14   -175.47                                   
REMARK 500  8 PHE A  50      109.23    -58.68                                   
REMARK 500  8 ARG A  54       40.14   -157.44                                   
REMARK 500  8 ASP A  56      -36.68    178.03                                   
REMARK 500  8 ASN A  58       58.84   -109.27                                   
REMARK 500  8 LYS A  67       85.88     53.85                                   
REMARK 500  8 THR A  68      113.07   -178.52                                   
REMARK 500  8 GLN A  99      109.91    -38.12                                   
REMARK 500  8 ARG A 101      164.27     58.34                                   
REMARK 500  8 ARG A 103       50.44    -99.46                                   
REMARK 500  8 GLU A 104     -174.97     51.52                                   
REMARK 500  8 GLU A 105     -173.27     68.57                                   
REMARK 500  8 GLU A 106       90.29     52.63                                   
REMARK 500  8 PHE A 109      101.53     51.17                                   
REMARK 500  8 ASP A 135      108.52     63.74                                   
REMARK 500  9 SER A   2      122.61     63.51                                   
REMARK 500  9 SER A   6      -61.22    -95.17                                   
REMARK 500  9 HIS A  21       64.69     62.10                                   
REMARK 500  9 LEU A  28      -98.18    -54.91                                   
REMARK 500  9 ASP A  32       43.54     39.85                                   
REMARK 500  9 SER A  35     -169.42    -54.15                                   
REMARK 500  9 GLU A  37     -177.48    -54.60                                   
REMARK 500  9 ASP A  38      -61.45     70.67                                   
REMARK 500  9 PRO A  41     -162.52    -75.02                                   
REMARK 500  9 PRO A  52     -166.82    -74.98                                   
REMARK 500  9 ASP A  53      141.37     68.55                                   
REMARK 500  9 LYS A  67       91.97     41.51                                   
REMARK 500  9 THR A  68      108.90   -179.42                                   
REMARK 500  9 ASN A  74       34.65     39.36                                   
REMARK 500  9 GLU A  89       48.16    -99.19                                   
REMARK 500  9 GLN A  99       95.95    -62.47                                   
REMARK 500  9 ALA A 100      -76.04    -86.26                                   
REMARK 500  9 VAL A 102      -80.84   -105.25                                   
REMARK 500  9 ARG A 103      -70.43    -52.96                                   
REMARK 500  9 GLU A 104     -179.77    -69.89                                   
REMARK 500  9 GLU A 105      -76.31    -86.25                                   
REMARK 500  9 LEU A 121       95.93    -63.53                                   
REMARK 500  9 ASP A 123       28.02   -159.46                                   
REMARK 500  9 HIS A 134      -69.79   -142.15                                   
REMARK 500  9 SER A 139       99.48   -173.62                                   
REMARK 500 10 SER A   2      154.86    179.11                                   
REMARK 500 10 SER A   3      148.85   -179.54                                   
REMARK 500 10 SER A   5       68.63   -157.20                                   
REMARK 500 10 SER A   6       83.26   -170.66                                   
REMARK 500 10 LEU A  28      -99.70    -50.71                                   
REMARK 500 10 SER A  35     -159.86    -80.36                                   
REMARK 500 10 GLU A  37      170.05     56.37                                   
REMARK 500 10 PRO A  41     -161.88    -75.02                                   
REMARK 500 10 ASP A  53      149.75     62.90                                   
REMARK 500 10 LYS A  67       97.03     47.99                                   
REMARK 500 10 THR A  68      114.67   -176.12                                   
REMARK 500 10 GLN A  99       89.52    -62.57                                   
REMARK 500 10 ALA A 100      -78.87    -60.55                                   
REMARK 500 10 VAL A 102      -71.83    -99.19                                   
REMARK 500 10 ARG A 103      -76.62    -64.51                                   
REMARK 500 10 GLU A 104      174.53    -48.49                                   
REMARK 500 10 GLU A 106       78.51     45.33                                   
REMARK 500 10 PHE A 109      112.16     58.93                                   
REMARK 500 10 LEU A 121       97.24    -68.45                                   
REMARK 500 10 ASP A 123       44.58    179.72                                   
REMARK 500 10 ASP A 124       24.29     47.62                                   
REMARK 500 10 HIS A 134       82.38   -167.23                                   
REMARK 500 10 SER A 140      167.66     60.61                                   
REMARK 500 11 SER A   6      -51.07   -161.60                                   
REMARK 500 11 VAL A  25      103.44   -162.46                                   
REMARK 500 11 LEU A  28      -99.25    -57.02                                   
REMARK 500 11 GLU A  37      -74.33    -46.73                                   
REMARK 500 11 ARG A  40      174.21     51.30                                   
REMARK 500 11 PRO A  41      -94.81    -74.99                                   
REMARK 500 11 ARG A  42      179.11    157.72                                   
REMARK 500 11 TYR A  45      122.64   -173.05                                   
REMARK 500 11 PHE A  50       88.13    -68.98                                   
REMARK 500 11 SER A  55      -44.14   -159.23                                   
REMARK 500 11 ASP A  56      -39.77   -173.61                                   
REMARK 500 11 LYS A  67       93.22     43.41                                   
REMARK 500 11 THR A  68      119.51   -175.88                                   
REMARK 500 11 ASN A  74       39.09     38.71                                   
REMARK 500 11 GLN A  99      108.65    -41.45                                   
REMARK 500 11 ARG A 101      155.71     58.95                                   
REMARK 500 11 ARG A 103      172.89     58.64                                   
REMARK 500 11 GLU A 104       99.02    -68.95                                   
REMARK 500 11 GLU A 105      163.27    176.40                                   
REMARK 500 11 GLU A 106      109.68     61.48                                   
REMARK 500 11 PHE A 109      111.33     55.95                                   
REMARK 500 11 LEU A 121       95.80    -63.71                                   
REMARK 500 11 ASP A 123       34.78   -170.12                                   
REMARK 500 11 HIS A 134      103.68   -174.56                                   
REMARK 500 11 SER A 139       84.06   -168.31                                   
REMARK 500 11 SER A 140      100.50    177.79                                   
REMARK 500 12 LEU A  28      -97.99    -61.60                                   
REMARK 500 12 GLU A  37      -79.99     62.31                                   
REMARK 500 12 ASP A  38      -20.97    148.79                                   
REMARK 500 12 PRO A  41     -162.59    -75.00                                   
REMARK 500 12 PHE A  50       99.07    -65.27                                   
REMARK 500 12 ARG A  54       58.67   -163.74                                   
REMARK 500 12 SER A  55       72.02   -172.17                                   
REMARK 500 12 ASP A  56     -171.53     63.25                                   
REMARK 500 12 LYS A  57      -73.35     68.54                                   
REMARK 500 12 ASN A  58       33.64    -98.99                                   
REMARK 500 12 LYS A  67       83.55     58.90                                   
REMARK 500 12 THR A  68      111.16   -179.70                                   
REMARK 500 12 ASN A  74       33.10     38.97                                   
REMARK 500 12 GLN A  99       96.64    -51.28                                   
REMARK 500 12 ARG A 101      -59.60     66.53                                   
REMARK 500 12 VAL A 102      155.43     63.49                                   
REMARK 500 12 GLU A 105       79.84   -109.88                                   
REMARK 500 12 PHE A 109       93.68     36.35                                   
REMARK 500 12 LEU A 121       89.09    -67.91                                   
REMARK 500 12 ASP A 123       38.15   -179.07                                   
REMARK 500 12 ASP A 135      123.84    170.13                                   
REMARK 500 12 SER A 136      -52.92   -140.43                                   
REMARK 500 13 SER A   2       87.15     53.05                                   
REMARK 500 13 SER A   5       98.92   -176.21                                   
REMARK 500 13 LEU A  28      -99.80    -51.45                                   
REMARK 500 13 SER A  35      177.89     53.32                                   
REMARK 500 13 GLU A  37      174.82    -46.42                                   
REMARK 500 13 ASP A  38        9.90     87.21                                   
REMARK 500 13 ARG A  40      162.49     54.90                                   
REMARK 500 13 PRO A  41      -92.19    -74.97                                   
REMARK 500 13 ARG A  42     -174.82    157.45                                   
REMARK 500 13 TYR A  45      122.01   -178.26                                   
REMARK 500 13 ASP A  53       96.17     72.82                                   
REMARK 500 13 ARG A  54       41.48   -106.23                                   
REMARK 500 13 ASP A  56      175.52     60.72                                   
REMARK 500 13 LYS A  57      -79.01     76.78                                   
REMARK 500 13 LYS A  67       92.05     41.77                                   
REMARK 500 13 THR A  68      113.70   -177.84                                   
REMARK 500 13 GLN A  99      102.26    -54.49                                   
REMARK 500 13 ALA A 100      -71.59    -99.37                                   
REMARK 500 13 ARG A 103      -54.00   -123.94                                   
REMARK 500 13 GLU A 104      161.44    -43.00                                   
REMARK 500 13 PHE A 109      105.88     52.80                                   
REMARK 500 13 ASP A 123       28.74   -161.59                                   
REMARK 500 13 SER A 136       89.03     42.76                                   
REMARK 500 14 SER A   6     -172.33    -54.35                                   
REMARK 500 14 HIS A  21       71.93     67.70                                   
REMARK 500 14 LEU A  28     -100.24    -54.92                                   
REMARK 500 14 SER A  35     -168.11    -62.23                                   
REMARK 500 14 GLU A  37      169.27    -43.97                                   
REMARK 500 14 ASP A  38       62.86    -68.93                                   
REMARK 500 14 PRO A  41     -161.68    -74.99                                   
REMARK 500 14 PHE A  50       89.41    -65.00                                   
REMARK 500 14 ARG A  54       90.74   -170.10                                   
REMARK 500 14 SER A  55      -74.44   -159.14                                   
REMARK 500 14 ASP A  56      -45.03   -158.63                                   
REMARK 500 14 ASN A  58       55.70   -113.02                                   
REMARK 500 14 LYS A  67       87.48     40.72                                   
REMARK 500 14 THR A  68      110.67   -178.72                                   
REMARK 500 14 ASN A  74       40.47     37.62                                   
REMARK 500 14 ARG A  88       38.78    -84.54                                   
REMARK 500 14 GLU A  89      -32.95   -149.62                                   
REMARK 500 14 ARG A 101      153.18     59.70                                   
REMARK 500 14 GLU A 105      -58.08   -176.45                                   
REMARK 500 14 ASP A 123       36.09   -176.03                                   
REMARK 500 14 ASP A 124       31.29     38.75                                   
REMARK 500 14 HIS A 134       64.19     64.49                                   
REMARK 500 14 ASP A 135       95.26   -171.50                                   
REMARK 500 14 SER A 136      -57.73   -156.35                                   
REMARK 500 14 SER A 139      132.08   -177.44                                   
REMARK 500 14 SER A 140      135.98    178.02                                   
REMARK 500 15 SER A   2      129.21   -174.36                                   
REMARK 500 15 SER A   6       98.60     62.35                                   
REMARK 500 15 HIS A  21       68.56     67.11                                   
REMARK 500 15 LEU A  28     -100.31    -61.12                                   
REMARK 500 15 GLU A  37      171.93    -51.64                                   
REMARK 500 15 ASP A  38      -74.29     62.64                                   
REMARK 500 15 PRO A  41     -162.48    -74.98                                   
REMARK 500 15 TYR A  45      127.55   -179.18                                   
REMARK 500 15 PHE A  50       96.37    -61.58                                   
REMARK 500 15 ASP A  53      153.54     68.35                                   
REMARK 500 15 SER A  55     -178.63   -171.65                                   
REMARK 500 15 ASP A  56     -178.84    -61.75                                   
REMARK 500 15 LYS A  57      -72.84     82.15                                   
REMARK 500 15 LYS A  67       88.24     49.80                                   
REMARK 500 15 THR A  68      114.22   -176.96                                   
REMARK 500 15 PHE A  87      -31.56    -36.18                                   
REMARK 500 15 ARG A  88      -77.69    -65.24                                   
REMARK 500 15 GLN A  99      100.10    -59.19                                   
REMARK 500 15 ARG A 101     -161.23     49.65                                   
REMARK 500 15 VAL A 102      -48.70   -170.15                                   
REMARK 500 15 ARG A 103       63.31   -106.06                                   
REMARK 500 15 GLU A 104      -33.73    167.33                                   
REMARK 500 15 GLU A 105       96.03     67.36                                   
REMARK 500 15 PHE A 109       90.91     41.76                                   
REMARK 500 15 LEU A 121       99.42    -64.14                                   
REMARK 500 15 ASP A 123       39.70    176.12                                   
REMARK 500 15 ASP A 124       32.97     38.72                                   
REMARK 500 15 HIS A 134       77.29   -176.30                                   
REMARK 500 15 SER A 136      -57.18   -129.83                                   
REMARK 500 15 SER A 139       91.38   -164.30                                   
REMARK 500 15 SER A 140      -58.32   -155.40                                   
REMARK 500 16 SER A   2      -61.91   -154.47                                   
REMARK 500 16 SER A   5      161.26     61.41                                   
REMARK 500 16 VAL A  19      -71.51    -51.54                                   
REMARK 500 16 LEU A  28      -99.35    -49.94                                   
REMARK 500 16 ARG A  36      -65.54   -107.23                                   
REMARK 500 16 GLU A  37      173.59    167.18                                   
REMARK 500 16 PRO A  41     -161.68    -74.99                                   
REMARK 500 16 TYR A  45      136.34   -171.81                                   
REMARK 500 16 ASP A  53      155.42    159.81                                   
REMARK 500 16 SER A  55      -59.01     84.86                                   
REMARK 500 16 ASP A  56     -165.59   -164.39                                   
REMARK 500 16 LYS A  57      -73.27     74.35                                   
REMARK 500 16 LYS A  67       95.24     48.14                                   
REMARK 500 16 THR A  68      114.69   -177.97                                   
REMARK 500 16 ASN A  74       38.24     38.91                                   
REMARK 500 16 GLN A  99       94.22    -50.59                                   
REMARK 500 16 ARG A 101      -69.20    -93.67                                   
REMARK 500 16 VAL A 102      148.44    176.22                                   
REMARK 500 16 ARG A 103     -179.15     60.09                                   
REMARK 500 16 GLU A 104       59.02    -90.17                                   
REMARK 500 16 GLU A 105      -67.57   -124.10                                   
REMARK 500 16 GLU A 106       48.36    -98.89                                   
REMARK 500 16 ASP A 123       34.79   -171.71                                   
REMARK 500 16 ASP A 124       25.08     48.80                                   
REMARK 500 16 SER A 139       80.83   -164.76                                   
REMARK 500 16 SER A 140       84.23     47.98                                   
REMARK 500 17 HIS A  21       62.87     68.03                                   
REMARK 500 17 LEU A  28     -100.42    -53.99                                   
REMARK 500 17 ASP A  32       42.63     73.73                                   
REMARK 500 17 GLU A  37      -80.25    -48.16                                   
REMARK 500 17 PRO A  41     -161.90    -75.03                                   
REMARK 500 17 TYR A  45      131.29   -173.38                                   
REMARK 500 17 PRO A  52     -168.99    -75.07                                   
REMARK 500 17 ASP A  53      135.58     77.01                                   
REMARK 500 17 ASP A  56     -154.48     40.13                                   
REMARK 500 17 LYS A  57      -82.23     67.97                                   
REMARK 500 17 LYS A  67       85.74     44.59                                   
REMARK 500 17 THR A  68      112.30   -178.15                                   
REMARK 500 17 ASN A  74       40.61     38.81                                   
REMARK 500 17 GLN A  99       90.32    -52.83                                   
REMARK 500 17 ARG A 101     -178.56     49.26                                   
REMARK 500 17 GLU A 104      156.39    171.86                                   
REMARK 500 17 GLU A 105       43.52    -87.57                                   
REMARK 500 17 PHE A 109      105.37     53.26                                   
REMARK 500 17 ASP A 123       32.26   -143.44                                   
REMARK 500 17 SER A 140       95.47     50.05                                   
REMARK 500 18 SER A   3      166.19     63.15                                   
REMARK 500 18 SER A   5      177.34    172.69                                   
REMARK 500 18 SER A   6     -177.45     57.71                                   
REMARK 500 18 VAL A  19      -71.25    -61.60                                   
REMARK 500 18 LEU A  28     -100.76    -59.28                                   
REMARK 500 18 SER A  35     -130.52    -89.40                                   
REMARK 500 18 ARG A  36      173.86     71.39                                   
REMARK 500 18 GLU A  37      133.09     65.05                                   
REMARK 500 18 ASP A  38      -59.30     73.69                                   
REMARK 500 18 PRO A  41     -162.64    -75.06                                   
REMARK 500 18 TYR A  45      122.96   -170.17                                   
REMARK 500 18 PRO A  52     -167.42    -75.04                                   
REMARK 500 18 ASP A  53      145.72     81.29                                   
REMARK 500 18 ARG A  54       29.63   -140.02                                   
REMARK 500 18 ASP A  56     -166.92    -57.83                                   
REMARK 500 18 LYS A  57      -72.14     72.97                                   
REMARK 500 18 ASN A  58       33.52    -93.42                                   
REMARK 500 18 LYS A  67       84.40     26.90                                   
REMARK 500 18 PHE A  87      -33.86    -39.20                                   
REMARK 500 18 GLU A  89      -45.47     82.95                                   
REMARK 500 18 GLN A  99       82.38    -59.15                                   
REMARK 500 18 ALA A 100      -88.25    -75.92                                   
REMARK 500 18 ARG A 103     -175.60     51.50                                   
REMARK 500 18 GLU A 105      174.88    179.48                                   
REMARK 500 18 GLU A 106       82.33     54.11                                   
REMARK 500 18 PHE A 109      111.32     56.15                                   
REMARK 500 18 ASP A 123       27.75   -157.39                                   
REMARK 500 19 SER A   2      -56.57   -143.32                                   
REMARK 500 19 SER A   3       85.58     42.02                                   
REMARK 500 19 ASP A  17       80.00   -100.88                                   
REMARK 500 19 LEU A  28     -100.80    -56.44                                   
REMARK 500 19 GLU A  37      -84.92    -46.49                                   
REMARK 500 19 ARG A  40      157.88     56.98                                   
REMARK 500 19 PRO A  41      -94.06    -75.02                                   
REMARK 500 19 ARG A  42      174.41    156.76                                   
REMARK 500 19 ASP A  53      105.28    152.59                                   
REMARK 500 19 SER A  55     -178.33   -171.53                                   
REMARK 500 19 ASP A  56      178.74    -52.45                                   
REMARK 500 19 LYS A  57      -76.15     76.40                                   
REMARK 500 19 LYS A  67       90.58     39.31                                   
REMARK 500 19 THR A  68      120.75    179.96                                   
REMARK 500 19 LYS A  72       84.23   -172.73                                   
REMARK 500 19 ASN A  74       36.58     35.22                                   
REMARK 500 19 GLN A  99       87.45    -55.16                                   
REMARK 500 19 ALA A 100      -85.63    -81.98                                   
REMARK 500 19 GLU A 104       96.18     47.79                                   
REMARK 500 19 GLU A 105      -47.50   -139.27                                   
REMARK 500 19 PHE A 109       84.77     33.88                                   
REMARK 500 19 ASP A 123       34.70   -173.00                                   
REMARK 500 19 ASP A 124       35.67     39.33                                   
REMARK 500 19 HIS A 134      102.12   -166.52                                   
REMARK 500 19 SER A 139      -59.01   -161.49                                   
REMARK 500 19 SER A 140      -58.69     75.01                                   
REMARK 500 20 SER A   3       80.65   -158.38                                   
REMARK 500 20 HIS A  21       61.43     61.90                                   
REMARK 500 20 LEU A  28      -98.72    -54.68                                   
REMARK 500 20 SER A  35     -163.63   -120.48                                   
REMARK 500 20 GLU A  37      -85.35    -39.33                                   
REMARK 500 20 ASP A  38       47.20   -109.91                                   
REMARK 500 20 PRO A  41     -160.80    -75.04                                   
REMARK 500 20 TYR A  45      124.48   -170.53                                   
REMARK 500 20 ASP A  53      111.86    152.00                                   
REMARK 500 20 SER A  55      -80.01   -119.47                                   
REMARK 500 20 LYS A  57       30.65     75.06                                   
REMARK 500 20 ASN A  58       36.61    167.20                                   
REMARK 500 20 LYS A  67       91.08     43.47                                   
REMARK 500 20 THR A  68      112.39   -178.36                                   
REMARK 500 20 GLU A  89       44.49    -92.44                                   
REMARK 500 20 GLN A  99      110.35    -39.67                                   
REMARK 500 20 ALA A 100      -85.82   -107.69                                   
REMARK 500 20 GLU A 104       86.87     46.23                                   
REMARK 500 20 GLU A 106      101.99     52.43                                   
REMARK 500 20 PHE A 109      116.93     57.57                                   
REMARK 500 20 ASP A 123       35.17   -169.92                                   
REMARK 500 20 SER A 136       87.49     41.02                                   
REMARK 500 20 SER A 139      121.30   -170.93                                   
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 900                                                                      
REMARK 900 RELATED ENTRIES                                                      
REMARK 900 RELATED ID: HSK002000733.2   RELATED DB: TARGETDB                    
DBREF  1V27 A    8   135  UNP    Q9UQ26   RIMS2_HUMAN    584    711             
SEQADV 1V27 GLY A    1  UNP  Q9UQ26              CLONING ARTIFACT               
SEQADV 1V27 SER A    2  UNP  Q9UQ26              CLONING ARTIFACT               
SEQADV 1V27 SER A    3  UNP  Q9UQ26              CLONING ARTIFACT               
SEQADV 1V27 GLY A    4  UNP  Q9UQ26              CLONING ARTIFACT               
SEQADV 1V27 SER A    5  UNP  Q9UQ26              CLONING ARTIFACT               
SEQADV 1V27 SER A    6  UNP  Q9UQ26              CLONING ARTIFACT               
SEQADV 1V27 GLY A    7  UNP  Q9UQ26              CLONING ARTIFACT               
SEQADV 1V27 SER A  136  UNP  Q9UQ26              CLONING ARTIFACT               
SEQADV 1V27 GLY A  137  UNP  Q9UQ26              CLONING ARTIFACT               
SEQADV 1V27 PRO A  138  UNP  Q9UQ26              CLONING ARTIFACT               
SEQADV 1V27 SER A  139  UNP  Q9UQ26              CLONING ARTIFACT               
SEQADV 1V27 SER A  140  UNP  Q9UQ26              CLONING ARTIFACT               
SEQADV 1V27 GLY A  141  UNP  Q9UQ26              CLONING ARTIFACT               
SEQRES   1 A  141  GLY SER SER GLY SER SER GLY GLY GLN LEU SER ILE LYS          
SEQRES   2 A  141  LEU TRP PHE ASP LYS VAL GLY HIS GLN LEU ILE VAL THR          
SEQRES   3 A  141  ILE LEU GLY ALA LYS ASP LEU PRO SER ARG GLU ASP GLY          
SEQRES   4 A  141  ARG PRO ARG ASN PRO TYR VAL LYS ILE TYR PHE LEU PRO          
SEQRES   5 A  141  ASP ARG SER ASP LYS ASN LYS ARG ARG THR LYS THR VAL          
SEQRES   6 A  141  LYS LYS THR LEU GLU PRO LYS TRP ASN GLN THR PHE ILE          
SEQRES   7 A  141  TYR SER PRO VAL HIS ARG ARG GLU PHE ARG GLU ARG MET          
SEQRES   8 A  141  LEU GLU ILE THR LEU TRP ASP GLN ALA ARG VAL ARG GLU          
SEQRES   9 A  141  GLU GLU SER GLU PHE LEU GLY GLU ILE LEU ILE GLU LEU          
SEQRES  10 A  141  GLU THR ALA LEU LEU ASP ASP GLU PRO HIS TRP TYR LYS          
SEQRES  11 A  141  LEU GLN THR HIS ASP SER GLY PRO SER SER GLY                  
HELIX    1   1 ARG A   85  GLU A   89  5                                   5    
HELIX    2   2 GLU A  118  ALA A  120  5                                   3    
SHEET    1   A 4 ILE A  78  TYR A  79  0                                        
SHEET    2   A 4 GLN A  22  LYS A  31 -1  N  LEU A  23   O  TYR A  79           
SHEET    3   A 4 GLN A   9  ASP A  17 -1  N  LYS A  13   O  THR A  26           
SHEET    4   A 4 PRO A 126  LYS A 130 -1  O  TYR A 129   N  LEU A  10           
SHEET    1   B 3 PRO A  44  LYS A  47  0                                        
SHEET    2   B 3 MET A  91  ASP A  98 -1  O  TRP A  97   N  TYR A  45           
SHEET    3   B 3 GLY A 111  GLU A 116 -1  O  ILE A 113   N  ILE A  94           
CISPEP   1 LEU A   51    PRO A   52          1        -0.02                     
CISPEP   2 SER A   80    PRO A   81          1         0.03                     
CISPEP   3 LEU A   51    PRO A   52          2        -0.03                     
CISPEP   4 SER A   80    PRO A   81          2         0.03                     
CISPEP   5 LEU A   51    PRO A   52          3         0.07                     
CISPEP   6 SER A   80    PRO A   81          3        -0.07                     
CISPEP   7 LEU A   51    PRO A   52          4        -0.08                     
CISPEP   8 SER A   80    PRO A   81          4        -0.03                     
CISPEP   9 LEU A   51    PRO A   52          5        -0.03                     
CISPEP  10 SER A   80    PRO A   81          5        -0.08                     
CISPEP  11 LEU A   51    PRO A   52          6         0.03                     
CISPEP  12 SER A   80    PRO A   81          6         0.00                     
CISPEP  13 LEU A   51    PRO A   52          7        -0.05                     
CISPEP  14 SER A   80    PRO A   81          7        -0.06                     
CISPEP  15 LEU A   51    PRO A   52          8        -0.04                     
CISPEP  16 SER A   80    PRO A   81          8         0.03                     
CISPEP  17 LEU A   51    PRO A   52          9        -0.01                     
CISPEP  18 SER A   80    PRO A   81          9         0.07                     
CISPEP  19 LEU A   51    PRO A   52         10        -0.03                     
CISPEP  20 SER A   80    PRO A   81         10         0.02                     
CISPEP  21 LEU A   51    PRO A   52         11         0.11                     
CISPEP  22 SER A   80    PRO A   81         11         0.07                     
CISPEP  23 LEU A   51    PRO A   52         12        -0.02                     
CISPEP  24 SER A   80    PRO A   81         12         0.08                     
CISPEP  25 LEU A   51    PRO A   52         13        -0.04                     
CISPEP  26 SER A   80    PRO A   81         13        -0.02                     
CISPEP  27 LEU A   51    PRO A   52         14         0.02                     
CISPEP  28 SER A   80    PRO A   81         14         0.06                     
CISPEP  29 LEU A   51    PRO A   52         15         0.04                     
CISPEP  30 SER A   80    PRO A   81         15         0.03                     
CISPEP  31 LEU A   51    PRO A   52         16        -0.04                     
CISPEP  32 SER A   80    PRO A   81         16         0.02                     
CISPEP  33 LEU A   51    PRO A   52         17         0.08                     
CISPEP  34 SER A   80    PRO A   81         17         0.01                     
CISPEP  35 LEU A   51    PRO A   52         18         0.06                     
CISPEP  36 SER A   80    PRO A   81         18        -0.04                     
CISPEP  37 LEU A   51    PRO A   52         19         0.03                     
CISPEP  38 SER A   80    PRO A   81         19        -0.03                     
CISPEP  39 LEU A   51    PRO A   52         20        -0.04                     
CISPEP  40 SER A   80    PRO A   81         20         0.02                     
CRYST1    1.000    1.000    1.000  90.00  90.00  90.00 P 1           1          
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      1.000000  0.000000  0.000000        0.00000                         
SCALE2      0.000000  1.000000  0.000000        0.00000                         
SCALE3      0.000000  0.000000  1.000000        0.00000                         
MODEL        1                                                                  
(ATOM LINES ARE NOT SHOWN.)
END                                                                             
DBGET integrated database retrieval system