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Database: PDB
Entry: 2DM0
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Original site: 2DM0 
HEADER    TRANSFERASE                             20-APR-06   2DM0              
TITLE     SOLUTION STRUCTURE OF THE SH2 DOMAIN OF HUMAN TYROSINE-               
TITLE    2 PROTEIN KINASE TXK                                                   
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: TYROSINE-PROTEIN KINASE TXK;                               
COMPND   3 CHAIN: A;                                                            
COMPND   4 FRAGMENT: SH2 DOMAIN;                                                
COMPND   5 EC: 2.7.10.2;                                                        
COMPND   6 ENGINEERED: YES                                                      
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE   3 ORGANISM_COMMON: HUMAN;                                              
SOURCE   4 ORGANISM_TAXID: 9606;                                                
SOURCE   5 GENE: TXK;                                                           
SOURCE   6 EXPRESSION_SYSTEM: CELL FREE SYNTHESIS;                              
SOURCE   7 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                              
SOURCE   8 EXPRESSION_SYSTEM_PLASMID: P050704-08;                               
SOURCE   9 OTHER_DETAILS: CELL FREE PROTEIN SYNTHESIS                           
KEYWDS    TEC FAMILY KINASE, STRUCTURAL GENOMICS, NPPSFA, NATIONAL              
KEYWDS   2 PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES,               
KEYWDS   3 RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI,               
KEYWDS   4 TRANSFERASE                                                          
EXPDTA    SOLUTION NMR                                                          
NUMMDL    20                                                                    
AUTHOR    H.ENDO,F.HAYASHI,M.YOSHIDA,S.YOKOYAMA,RIKEN STRUCTURAL                
AUTHOR   2 GENOMICS/PROTEOMICS INITIATIVE (RSGI)                                
REVDAT   2   24-FEB-09 2DM0    1       VERSN                                    
REVDAT   1   20-OCT-06 2DM0    0                                                
JRNL        AUTH   H.ENDO,F.HAYASHI,M.YOSHIDA,S.YOKOYAMA                        
JRNL        TITL   SOLUTION STRUCTURE OF THE SH2 DOMAIN OF HUMAN                
JRNL        TITL 2 TYROSINE-PROTEIN KINASE TXK                                  
JRNL        REF    TO BE PUBLISHED                                              
JRNL        REFN                                                                
REMARK   1                                                                      
REMARK   2                                                                      
REMARK   2 RESOLUTION. NOT APPLICABLE.                                          
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   PROGRAM     : CYANA 2.0.17                                         
REMARK   3   AUTHORS     : GUNTERT,P.                                           
REMARK   3                                                                      
REMARK   3  OTHER REFINEMENT REMARKS: NULL                                      
REMARK   4                                                                      
REMARK   4 2DM0 COMPLIES WITH FORMAT V. 3.15, 01-DEC-08                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBJ ON 21-APR-06.                  
REMARK 100 THE RCSB ID CODE IS RCSB025571.                                      
REMARK 210                                                                      
REMARK 210 EXPERIMENTAL DETAILS                                                 
REMARK 210  EXPERIMENT TYPE                : NMR                                
REMARK 210  TEMPERATURE           (KELVIN) : 293                                
REMARK 210  PH                             : 7.0                                
REMARK 210  IONIC STRENGTH                 : 120MM                              
REMARK 210  PRESSURE                       : AMBIENT                            
REMARK 210  SAMPLE CONTENTS                : 1.06MM 13C,15N-LABELED             
REMARK 210                                   PROTEIN; 20MM D-TRIS-              
REMARK 210                                   HCL(PH7.0); 100MM NACL; 1MM D-     
REMARK 210                                   DTT; 0.02% NAN3; 90% H2O; 10%      
REMARK 210                                   D2O                                
REMARK 210                                                                      
REMARK 210  NMR EXPERIMENTS CONDUCTED      : 3D_15N-SEPARATED_NOESY, 3D_        
REMARK 210                                   13C-SEPARATED_NOESY                
REMARK 210  SPECTROMETER FIELD STRENGTH    : 800 MHZ, 900 MHZ                   
REMARK 210  SPECTROMETER MODEL             : INOVA                              
REMARK 210  SPECTROMETER MANUFACTURER      : VARIAN                             
REMARK 210                                                                      
REMARK 210  STRUCTURE DETERMINATION.                                            
REMARK 210   SOFTWARE USED                 : VNMR 6.1C, NMRPIPE 20031121,       
REMARK 210                                   NMRVIEW 5.0.4, KUJIRA 0.955,       
REMARK 210                                   CYANA 2.0.17                       
REMARK 210   METHOD USED                   : TORSION ANGLE DYNAMICS             
REMARK 210                                                                      
REMARK 210 CONFORMERS, NUMBER CALCULATED   : 100                                
REMARK 210 CONFORMERS, NUMBER SUBMITTED    : 20                                 
REMARK 210 CONFORMERS, SELECTION CRITERIA  : TARGET FUNCTION,STRUCTURES         
REMARK 210                                   WITH THE LOWEST ENERGY,            
REMARK 210                                   STRUCTURES WITH THE LEAST          
REMARK 210                                   RESTRAINT VIOLATIONS               
REMARK 210                                                                      
REMARK 210 BEST REPRESENTATIVE CONFORMER IN THIS ENSEMBLE : 1                   
REMARK 210                                                                      
REMARK 210 REMARK: SPECTROMETER_ID 1 FOR 3D_15N-SEPARATED_NOESY;                
REMARK 210  SPECTROMETER_ID 2 FOR 3D_13C-SEPARATED_NOESY                        
REMARK 215                                                                      
REMARK 215 NMR STUDY                                                            
REMARK 215 THE COORDINATES IN THIS ENTRY WERE GENERATED FROM SOLUTION           
REMARK 215 NMR DATA.  PROTEIN DATA BANK CONVENTIONS REQUIRE THAT                
REMARK 215 CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES ON              
REMARK 215 THESE RECORDS ARE MEANINGLESS.                                       
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: TORSION ANGLES                                             
REMARK 500                                                                      
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:            
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)                    
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-           
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400            
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        PSI       PHI                                   
REMARK 500  1 ALA A  40      104.60    -47.47                                   
REMARK 500  1 ARG A  47      -26.10    -37.45                                   
REMARK 500  1 ALA A  60      177.68    -48.38                                   
REMARK 500  1 ARG A  62       39.08    -85.24                                   
REMARK 500  1 SER A  63       42.20     34.95                                   
REMARK 500  1 ARG A  86      -32.19   -131.26                                   
REMARK 500  1 ALA A 103      -72.71    -36.21                                   
REMARK 500  1 ALA A 104       38.42     73.42                                   
REMARK 500  1 LEU A 106       40.32     33.77                                   
REMARK 500  1 LEU A 110      122.31    -35.24                                   
REMARK 500  1 PRO A 113       79.93    -69.76                                   
REMARK 500  1 SER A 120      146.42   -173.59                                   
REMARK 500  1 SER A 124      167.24    -49.82                                   
REMARK 500  2 SER A   2       42.08     70.69                                   
REMARK 500  2 SER A   3      139.63   -172.10                                   
REMARK 500  2 GLU A  38      150.35    -39.28                                   
REMARK 500  2 ALA A  40      104.88    -33.44                                   
REMARK 500  2 ARG A  61       40.18    -97.89                                   
REMARK 500  2 SER A  63      -38.65    -30.79                                   
REMARK 500  2 GLU A  65     -174.96    -52.85                                   
REMARK 500  2 ALA A  66      164.13    -41.80                                   
REMARK 500  2 GLU A  85       26.49     45.27                                   
REMARK 500  2 ARG A  86      -31.13   -130.19                                   
REMARK 500  2 HIS A  99      -35.53    -36.99                                   
REMARK 500  2 ALA A 103       41.36    -84.45                                   
REMARK 500  2 ALA A 104      135.12    -33.84                                   
REMARK 500  2 MET A 107      142.39    -37.41                                   
REMARK 500  2 ARG A 109      151.21    -49.48                                   
REMARK 500  2 PRO A 113       88.39    -69.74                                   
REMARK 500  3 LYS A   9      154.72    -44.59                                   
REMARK 500  3 GLU A  38      117.30    -34.39                                   
REMARK 500  3 SER A  46       95.81    -66.48                                   
REMARK 500  3 ARG A  47      -26.58    -37.86                                   
REMARK 500  3 THR A  64      -19.28    -48.41                                   
REMARK 500  3 VAL A  83      -51.03   -127.96                                   
REMARK 500  3 ARG A  86      -32.98   -134.06                                   
REMARK 500  3 PRO A  93        0.45    -69.70                                   
REMARK 500  3 ALA A 103       81.88    -67.03                                   
REMARK 500  3 ALA A 104       80.67    -67.56                                   
REMARK 500  3 LEU A 106       49.92     35.15                                   
REMARK 500  3 THR A 108      141.57    -39.81                                   
REMARK 500  3 PRO A 113       79.66    -69.72                                   
REMARK 500  3 VAL A 114      118.87    -38.05                                   
REMARK 500  3 SER A 119      140.93   -174.96                                   
REMARK 500  4 SER A   5       42.52     35.92                                   
REMARK 500  4 ILE A  10      127.96    -36.65                                   
REMARK 500  4 HIS A  20       93.28    -66.44                                   
REMARK 500  4 ASN A  22       41.50     74.15                                   
REMARK 500  4 GLU A  38      145.62    -37.50                                   
REMARK 500  4 ALA A  40      116.06    -33.01                                   
REMARK 500  4 ALA A  60      163.07    -43.77                                   
REMARK 500  4 THR A  64       39.25    -83.37                                   
REMARK 500  4 GLU A  85       27.59     43.39                                   
REMARK 500  4 ARG A  86      -30.85   -130.89                                   
REMARK 500  4 HIS A  99      -36.90    -37.86                                   
REMARK 500  4 LEU A 106      156.55    -36.86                                   
REMARK 500  4 MET A 107       36.83    -86.74                                   
REMARK 500  4 LEU A 110      116.89    -33.48                                   
REMARK 500  4 PRO A 113       79.58    -69.71                                   
REMARK 500  4 MET A 117       89.55    -51.33                                   
REMARK 500  4 SER A 120      -62.96   -133.45                                   
REMARK 500  5 ARG A  62      169.60    -49.61                                   
REMARK 500  5 GLU A  85       32.90     33.11                                   
REMARK 500  5 PRO A  93        1.48    -69.76                                   
REMARK 500  5 ALA A 103       97.45    -69.44                                   
REMARK 500  5 MET A 107      -33.72    -33.82                                   
REMARK 500  5 LEU A 110      101.25    -50.35                                   
REMARK 500  5 PRO A 113       79.68    -69.78                                   
REMARK 500  5 VAL A 114      105.28    -42.53                                   
REMARK 500  6 SER A   2      149.78    -39.45                                   
REMARK 500  6 SER A   3       88.10    -60.31                                   
REMARK 500  6 ASN A   8      150.98    -40.03                                   
REMARK 500  6 ILE A  10      132.08    -37.33                                   
REMARK 500  6 ALA A  40       96.97    -38.48                                   
REMARK 500  6 ARG A  47      -31.88    -35.05                                   
REMARK 500  6 THR A  64       35.66    -83.16                                   
REMARK 500  6 ARG A  86      -32.09   -131.17                                   
REMARK 500  6 LEU A 110      102.13    -54.99                                   
REMARK 500  6 PRO A 113       90.05    -69.72                                   
REMARK 500  6 VAL A 114      130.44    -35.31                                   
REMARK 500  7 TYR A  19       78.92   -107.45                                   
REMARK 500  7 ASN A  22       43.77     72.55                                   
REMARK 500  7 LYS A  37      118.56   -161.06                                   
REMARK 500  7 GLU A  38      136.82    -33.34                                   
REMARK 500  7 ALA A  40       99.87    -44.36                                   
REMARK 500  7 ARG A  62       26.06     38.73                                   
REMARK 500  7 SER A  63      -60.64   -121.23                                   
REMARK 500  7 GLU A  65      164.69    -41.69                                   
REMARK 500  7 ALA A  66      117.42    -29.81                                   
REMARK 500  7 ARG A  86      -31.73   -130.76                                   
REMARK 500  7 PRO A  93        1.21    -69.78                                   
REMARK 500  7 ALA A 103       92.16    -68.71                                   
REMARK 500  7 PRO A 113       80.51    -69.76                                   
REMARK 500  7 VAL A 114      107.08    -45.73                                   
REMARK 500  7 SER A 124      145.21   -171.84                                   
REMARK 500  8 SER A   6      -44.53   -131.93                                   
REMARK 500  8 ASN A  22       44.12     75.00                                   
REMARK 500  8 ALA A  40      121.51    -39.29                                   
REMARK 500  8 ARG A  47      -36.96    -35.43                                   
REMARK 500  8 ALA A  60      120.60    -33.01                                   
REMARK 500  8 ARG A  61       42.92    -81.41                                   
REMARK 500  8 ARG A  62       35.10     37.96                                   
REMARK 500  8 THR A  64      -66.47   -123.86                                   
REMARK 500  8 ALA A  66      153.78    -39.47                                   
REMARK 500  8 ARG A  86      -33.45   -134.85                                   
REMARK 500  8 ALA A 104       76.74   -116.25                                   
REMARK 500  8 PRO A 113       79.36    -69.73                                   
REMARK 500  8 SER A 120      162.30    -49.00                                   
REMARK 500  8 SER A 123      124.63    -35.46                                   
REMARK 500  9 ASN A  22       43.09     72.26                                   
REMARK 500  9 ALA A  60      175.98    -52.07                                   
REMARK 500  9 ARG A  62       49.66     35.85                                   
REMARK 500  9 THR A  64       42.15    -79.82                                   
REMARK 500  9 ARG A  86      -32.50   -131.90                                   
REMARK 500  9 LEU A 106     -173.54    -59.88                                   
REMARK 500  9 PRO A 113       79.74    -69.82                                   
REMARK 500  9 VAL A 114      110.40    -33.33                                   
REMARK 500  9 MET A 117       89.86    -55.89                                   
REMARK 500 10 ILE A  10      150.04    -33.84                                   
REMARK 500 10 ALA A  40      120.19    -38.34                                   
REMARK 500 10 ARG A  47      -27.72    -37.55                                   
REMARK 500 10 ALA A  60      173.11    -56.62                                   
REMARK 500 10 SER A  63       41.95    -81.96                                   
REMARK 500 10 ARG A  86      -32.99   -132.37                                   
REMARK 500 10 ALA A 103       97.88    -67.18                                   
REMARK 500 10 PRO A 113       79.93    -69.72                                   
REMARK 500 10 MET A 117       89.85    -63.26                                   
REMARK 500 11 ILE A  10      150.39    -37.64                                   
REMARK 500 11 ASN A  22       42.87     72.16                                   
REMARK 500 11 ALA A  60      178.65    -50.83                                   
REMARK 500 11 ARG A  61      -54.48   -124.62                                   
REMARK 500 11 GLU A  65      174.20    -47.13                                   
REMARK 500 11 ARG A  86      -32.70   -133.23                                   
REMARK 500 11 PRO A 113       79.77    -69.87                                   
REMARK 500 11 VAL A 114      126.32    -37.95                                   
REMARK 500 11 MET A 117       39.24    -94.18                                   
REMARK 500 12 THR A  11       51.95   -109.62                                   
REMARK 500 12 LYS A  37      112.46   -160.86                                   
REMARK 500 12 GLU A  38      136.04    -33.74                                   
REMARK 500 12 ARG A  47      -36.72    -34.65                                   
REMARK 500 12 ARG A  62      156.74    -40.16                                   
REMARK 500 12 SER A  63      -71.43    -42.03                                   
REMARK 500 12 GLU A  85       31.36     34.29                                   
REMARK 500 12 HIS A  99      -38.32    -38.27                                   
REMARK 500 12 PRO A 113       79.29    -69.74                                   
REMARK 500 12 VAL A 114      129.39    -37.96                                   
REMARK 500 12 SER A 123      153.62    -48.07                                   
REMARK 500 13 ALA A  40      106.30    -48.33                                   
REMARK 500 13 SER A  46      139.65    -39.74                                   
REMARK 500 13 MET A  58      -60.02   -103.42                                   
REMARK 500 13 ARG A  62      -61.74   -100.58                                   
REMARK 500 13 SER A  63      167.84    -46.55                                   
REMARK 500 13 ALA A  66      121.55    -33.05                                   
REMARK 500 13 GLU A  85       28.11     36.58                                   
REMARK 500 13 ALA A 103       96.67    -59.91                                   
REMARK 500 13 LEU A 110      108.10    -52.05                                   
REMARK 500 13 PRO A 113       84.62    -69.77                                   
REMARK 500 13 VAL A 114      128.72    -34.06                                   
REMARK 500 14 SER A   2      168.03    -47.58                                   
REMARK 500 14 ALA A  40      108.38    -41.91                                   
REMARK 500 14 ARG A  47      -34.91    -35.09                                   
REMARK 500 14 ALA A  60       78.17    -62.26                                   
REMARK 500 14 ALA A  66      159.95    -39.12                                   
REMARK 500 14 ASN A  76     -173.31    -66.01                                   
REMARK 500 14 GLU A  85       26.85     48.42                                   
REMARK 500 14 ARG A  86      -31.99   -131.32                                   
REMARK 500 14 PRO A  93        2.96    -69.84                                   
REMARK 500 14 ALA A 103       75.51    -64.42                                   
REMARK 500 14 PRO A 113       79.96    -69.78                                   
REMARK 500 14 SER A 120       25.04     43.40                                   
REMARK 500 14 PRO A 122        5.99    -69.68                                   
REMARK 500 15 ILE A  10      122.89    -35.73                                   
REMARK 500 15 ASN A  22       44.73     74.74                                   
REMARK 500 15 GLU A  38      115.96    -36.56                                   
REMARK 500 15 ARG A  47      -30.35    -35.94                                   
REMARK 500 15 THR A  64       37.46    -87.58                                   
REMARK 500 15 VAL A  83      -45.85   -130.91                                   
REMARK 500 15 ARG A  86      -32.08   -133.43                                   
REMARK 500 15 HIS A  99      -36.05    -36.11                                   
REMARK 500 15 PRO A 113       83.31    -69.76                                   
REMARK 500 15 VAL A 114      124.45    -33.96                                   
REMARK 500 15 MET A 117       90.15    -54.21                                   
REMARK 500 15 PRO A 122     -172.08    -69.84                                   
REMARK 500 16 SER A   2      -60.20   -107.90                                   
REMARK 500 16 ILE A  10      135.03    -35.97                                   
REMARK 500 16 ALA A  40      109.93    -36.30                                   
REMARK 500 16 ARG A  47      -36.05    -34.58                                   
REMARK 500 16 ALA A  60      175.98    -59.90                                   
REMARK 500 16 ARG A  86      -33.09   -133.22                                   
REMARK 500 16 PRO A  93        1.13    -69.78                                   
REMARK 500 16 ALA A 103       93.28    -60.44                                   
REMARK 500 16 PRO A 113       79.16    -69.70                                   
REMARK 500 16 VAL A 114      112.68    -38.38                                   
REMARK 500 17 LYS A   9       37.91    -83.07                                   
REMARK 500 17 THR A  11       51.16     71.22                                   
REMARK 500 17 TYR A  19       75.06   -104.30                                   
REMARK 500 17 ALA A  40      108.95    -49.58                                   
REMARK 500 17 ARG A  62       35.07     35.04                                   
REMARK 500 17 SER A  63      -54.84   -128.77                                   
REMARK 500 17 GLU A  65      169.50    -44.33                                   
REMARK 500 17 ALA A  66      119.56    -32.48                                   
REMARK 500 17 ARG A  86      -32.34   -132.97                                   
REMARK 500 17 PRO A  93        2.58    -69.71                                   
REMARK 500 17 MET A 107      -39.74    -34.69                                   
REMARK 500 17 ARG A 111      -50.72   -134.98                                   
REMARK 500 17 PRO A 113       79.60    -69.86                                   
REMARK 500 17 PRO A 122        2.70    -69.67                                   
REMARK 500 18 SER A   3       42.18     39.38                                   
REMARK 500 18 ASN A  22       40.30     73.26                                   
REMARK 500 18 ARG A  47      -32.78    -35.26                                   
REMARK 500 18 THR A  64      176.24    -49.38                                   
REMARK 500 18 ALA A  66      155.02    -36.40                                   
REMARK 500 18 VAL A  83      -53.51   -125.40                                   
REMARK 500 18 ARG A  86      -32.29   -134.95                                   
REMARK 500 18 PRO A  93        0.73    -69.92                                   
REMARK 500 18 HIS A  99      -34.64    -38.84                                   
REMARK 500 18 LEU A 106       76.00    -66.88                                   
REMARK 500 18 MET A 107       29.87     37.13                                   
REMARK 500 18 LEU A 110      109.31    -32.52                                   
REMARK 500 18 PRO A 113       79.56    -69.77                                   
REMARK 500 18 MET A 117       89.57    -57.56                                   
REMARK 500 19 SER A   3       41.99    -94.42                                   
REMARK 500 19 ARG A  61       41.13    -81.75                                   
REMARK 500 19 VAL A  83      -50.17   -125.39                                   
REMARK 500 19 ARG A  86      -32.55   -133.25                                   
REMARK 500 19 HIS A  99      -33.67    -34.38                                   
REMARK 500 19 MET A 107     -178.51    -55.96                                   
REMARK 500 19 THR A 108      137.77    -30.23                                   
REMARK 500 19 PRO A 113       79.75    -69.73                                   
REMARK 500 19 VAL A 114      121.62    -37.93                                   
REMARK 500 19 SER A 120      -62.63   -127.02                                   
REMARK 500 20 SER A   6      142.13   -174.69                                   
REMARK 500 20 ASN A   8      125.12   -174.72                                   
REMARK 500 20 TYR A  19       78.42   -108.24                                   
REMARK 500 20 ALA A  40      106.92    -42.19                                   
REMARK 500 20 ARG A  47      -30.29    -35.89                                   
REMARK 500 20 ARG A  62       45.08     37.93                                   
REMARK 500 20 GLU A  65      178.25    -57.08                                   
REMARK 500 20 VAL A  83      -51.73   -121.54                                   
REMARK 500 20 GLU A  85       28.50     44.72                                   
REMARK 500 20 ARG A  86      -32.35   -133.35                                   
REMARK 500 20 PRO A  93        0.53    -69.76                                   
REMARK 500 20 ALA A 103       45.43    -78.84                                   
REMARK 500 20 ALA A 104      115.63    -34.07                                   
REMARK 500 20 LEU A 106     -175.56    -56.46                                   
REMARK 500 20 PRO A 113       80.47    -69.71                                   
REMARK 500 20 VAL A 114      124.53    -34.18                                   
REMARK 500 20 SER A 119      142.31   -174.58                                   
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 900                                                                      
REMARK 900 RELATED ENTRIES                                                      
REMARK 900 RELATED ID: HSI002012296.1   RELATED DB: TARGETDB                    
DBREF  2DM0 A    8   119  UNP    P42681   TXK_HUMAN      140    251             
SEQADV 2DM0 GLY A    1  UNP  P42681              CLONING ARTIFACT               
SEQADV 2DM0 SER A    2  UNP  P42681              CLONING ARTIFACT               
SEQADV 2DM0 SER A    3  UNP  P42681              CLONING ARTIFACT               
SEQADV 2DM0 GLY A    4  UNP  P42681              CLONING ARTIFACT               
SEQADV 2DM0 SER A    5  UNP  P42681              CLONING ARTIFACT               
SEQADV 2DM0 SER A    6  UNP  P42681              CLONING ARTIFACT               
SEQADV 2DM0 GLY A    7  UNP  P42681              CLONING ARTIFACT               
SEQADV 2DM0 SER A  120  UNP  P42681              CLONING ARTIFACT               
SEQADV 2DM0 GLY A  121  UNP  P42681              CLONING ARTIFACT               
SEQADV 2DM0 PRO A  122  UNP  P42681              CLONING ARTIFACT               
SEQADV 2DM0 SER A  123  UNP  P42681              CLONING ARTIFACT               
SEQADV 2DM0 SER A  124  UNP  P42681              CLONING ARTIFACT               
SEQADV 2DM0 GLY A  125  UNP  P42681              CLONING ARTIFACT               
SEQRES   1 A  125  GLY SER SER GLY SER SER GLY ASN LYS ILE THR ASN LEU          
SEQRES   2 A  125  GLU ILE TYR GLU TRP TYR HIS ARG ASN ILE THR ARG ASN          
SEQRES   3 A  125  GLN ALA GLU HIS LEU LEU ARG GLN GLU SER LYS GLU GLY          
SEQRES   4 A  125  ALA PHE ILE VAL ARG ASP SER ARG HIS LEU GLY SER TYR          
SEQRES   5 A  125  THR ILE SER VAL PHE MET GLY ALA ARG ARG SER THR GLU          
SEQRES   6 A  125  ALA ALA ILE LYS HIS TYR GLN ILE LYS LYS ASN ASP SER          
SEQRES   7 A  125  GLY GLN TRP TYR VAL ALA GLU ARG HIS ALA PHE GLN SER          
SEQRES   8 A  125  ILE PRO GLU LEU ILE TRP TYR HIS GLN HIS ASN ALA ALA          
SEQRES   9 A  125  GLY LEU MET THR ARG LEU ARG TYR PRO VAL GLY LEU MET          
SEQRES  10 A  125  GLY SER SER GLY PRO SER SER GLY                              
HELIX    1   1 THR A   24  SER A   36  1                                  13    
HELIX    2   2 SER A   91  GLN A  100  1                                  10    
SHEET    1   A 4 VAL A  43  SER A  46  0                                        
SHEET    2   A 4 LEU A  49  PHE A  57 -1  O  THR A  53   N  ARG A  44           
SHEET    3   A 4 ILE A  68  LYS A  75 -1  O  TYR A  71   N  ILE A  54           
SHEET    4   A 4 TRP A  81  TYR A  82 -1  O  TYR A  82   N  LYS A  74           
CRYST1    1.000    1.000    1.000  90.00  90.00  90.00 P 1           1          
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      1.000000  0.000000  0.000000        0.00000                         
SCALE2      0.000000  1.000000  0.000000        0.00000                         
SCALE3      0.000000  0.000000  1.000000        0.00000                         
MODEL        1                                                                  
(ATOM LINES ARE NOT SHOWN.)
END                                                                             
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