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Database: PDB
Entry: 2FUG
LinkDB: 2FUG
Original site: 2FUG 
HEADER    OXIDOREDUCTASE                          26-JAN-06   2FUG              
TITLE     CRYSTAL STRUCTURE OF THE HYDROPHILIC DOMAIN OF RESPIRATORY COMPLEX I  
TITLE    2 FROM THERMUS THERMOPHILUS                                            
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: NADH-QUINONE OXIDOREDUCTASE CHAIN 1;                       
COMPND   3 CHAIN: 1, A, J, S;                                                   
COMPND   4 FRAGMENT: HYDROPHILIC DOMAIN;                                        
COMPND   5 SYNONYM: NADH DEHYDROGENASE I, CHAIN 1, NDH-1, CHAIN 1;              
COMPND   6 EC: 1.6.99.5;                                                        
COMPND   7 MOL_ID: 2;                                                           
COMPND   8 MOLECULE: NADH-QUINONE OXIDOREDUCTASE CHAIN 2;                       
COMPND   9 CHAIN: 2, B, K, T;                                                   
COMPND  10 SYNONYM: NADH DEHYDROGENASE I, CHAIN 2, NDH-1, CHAIN 2;              
COMPND  11 EC: 1.6.99.5;                                                        
COMPND  12 MOL_ID: 3;                                                           
COMPND  13 MOLECULE: NADH-QUINONE OXIDOREDUCTASE CHAIN 3;                       
COMPND  14 CHAIN: 3, C, L, U;                                                   
COMPND  15 SYNONYM: NADH DEHYDROGENASE I, CHAIN 3, NDH-1, CHAIN 3;              
COMPND  16 EC: 1.6.99.5;                                                        
COMPND  17 MOL_ID: 4;                                                           
COMPND  18 MOLECULE: NADH-QUINONE OXIDOREDUCTASE CHAIN 4;                       
COMPND  19 CHAIN: 4, D, M, V;                                                   
COMPND  20 SYNONYM: NADH DEHYDROGENASE I, CHAIN 4, NDH-1, CHAIN 4;              
COMPND  21 EC: 1.6.99.5;                                                        
COMPND  22 MOL_ID: 5;                                                           
COMPND  23 MOLECULE: NADH-QUINONE OXIDOREDUCTASE CHAIN 5;                       
COMPND  24 CHAIN: 5, E, N, W;                                                   
COMPND  25 SYNONYM: NADH DEHYDROGENASE I, CHAIN 5, NDH-1, CHAIN 5;              
COMPND  26 EC: 1.6.99.5;                                                        
COMPND  27 MOL_ID: 6;                                                           
COMPND  28 MOLECULE: NADH-QUINONE OXIDOREDUCTASE CHAIN 6;                       
COMPND  29 CHAIN: 6, F, O, X;                                                   
COMPND  30 SYNONYM: NADH DEHYDROGENASE I, CHAIN 6, NDH-1, CHAIN 6;              
COMPND  31 EC: 1.6.99.5;                                                        
COMPND  32 MOL_ID: 7;                                                           
COMPND  33 MOLECULE: NADH-QUINONE OXIDOREDUCTASE CHAIN 9;                       
COMPND  34 CHAIN: 9, G, P, Y;                                                   
COMPND  35 SYNONYM: NADH DEHYDROGENASE I, CHAIN 9, NDH-1, CHAIN 9;              
COMPND  36 EC: 1.6.99.5;                                                        
COMPND  37 MOL_ID: 8;                                                           
COMPND  38 MOLECULE: CONSERVED HYPOTHETICAL PROTEIN;                            
COMPND  39 CHAIN: 7, H, Q, Z                                                    
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;                           
SOURCE   3 ORGANISM_TAXID: 300852;                                              
SOURCE   4 STRAIN: HB8;                                                         
SOURCE   5 MOL_ID: 2;                                                           
SOURCE   6 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;                           
SOURCE   7 ORGANISM_TAXID: 300852;                                              
SOURCE   8 STRAIN: HB8;                                                         
SOURCE   9 MOL_ID: 3;                                                           
SOURCE  10 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;                           
SOURCE  11 ORGANISM_TAXID: 300852;                                              
SOURCE  12 STRAIN: HB8;                                                         
SOURCE  13 MOL_ID: 4;                                                           
SOURCE  14 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;                           
SOURCE  15 ORGANISM_TAXID: 300852;                                              
SOURCE  16 STRAIN: HB8;                                                         
SOURCE  17 MOL_ID: 5;                                                           
SOURCE  18 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;                           
SOURCE  19 ORGANISM_TAXID: 300852;                                              
SOURCE  20 STRAIN: HB8;                                                         
SOURCE  21 MOL_ID: 6;                                                           
SOURCE  22 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;                           
SOURCE  23 ORGANISM_TAXID: 300852;                                              
SOURCE  24 STRAIN: HB8;                                                         
SOURCE  25 MOL_ID: 7;                                                           
SOURCE  26 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;                           
SOURCE  27 ORGANISM_TAXID: 300852;                                              
SOURCE  28 STRAIN: HB8;                                                         
SOURCE  29 MOL_ID: 8;                                                           
SOURCE  30 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;                           
SOURCE  31 ORGANISM_TAXID: 300852;                                              
SOURCE  32 STRAIN: HB8                                                          
KEYWDS    OXIDOREDUCTASE, ELECTRON TRANSPORT, RESPIRATORY CHAIN                 
EXPDTA    X-RAY DIFFRACTION                                                     
AUTHOR    L.A.SAZANOV,P.HINCHLIFFE                                              
REVDAT   7   18-OCT-17 2FUG    1       REMARK                                   
REVDAT   6   13-JUL-11 2FUG    1       VERSN                                    
REVDAT   5   24-MAR-09 2FUG    1       ATOM   CONECT                            
REVDAT   4   24-FEB-09 2FUG    1       VERSN                                    
REVDAT   3   21-MAR-06 2FUG    1       JRNL                                     
REVDAT   2   07-MAR-06 2FUG    1       REMARK                                   
REVDAT   1   14-FEB-06 2FUG    0                                                
JRNL        AUTH   L.A.SAZANOV,P.HINCHLIFFE                                     
JRNL        TITL   STRUCTURE OF THE HYDROPHILIC DOMAIN OF RESPIRATORY COMPLEX I 
JRNL        TITL 2 FROM THERMUS THERMOPHILUS.                                   
JRNL        REF    SCIENCE                       V. 311  1430 2006              
JRNL        REFN                   ISSN 0036-8075                               
JRNL        PMID   16469879                                                     
JRNL        DOI    10.1126/SCIENCE.1123809                                      
REMARK   1                                                                      
REMARK   1 REFERENCE 1                                                          
REMARK   1  AUTH   P.HINCHLIFFE,L.A.SAZANOV                                     
REMARK   1  TITL   ORGANIZATION OF IRON-SULFUR CLUSTERS IN RESPIRATORY COMPLEX  
REMARK   1  TITL 2 I                                                            
REMARK   1  REF    SCIENCE                       V. 309   771 2005              
REMARK   1  REFN                   ISSN 0036-8075                               
REMARK   2                                                                      
REMARK   2 RESOLUTION.    3.30 ANGSTROMS.                                       
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   PROGRAM     : CNS                                                  
REMARK   3   AUTHORS     : BRUNGER,ADAMS,CLORE,DELANO,GROS,GROSSE-              
REMARK   3               : KUNSTLEVE,JIANG,KUSZEWSKI,NILGES,PANNU,              
REMARK   3               : READ,RICE,SIMONSON,WARREN                            
REMARK   3                                                                      
REMARK   3  REFINEMENT TARGET : ENGH & HUBER                                    
REMARK   3                                                                      
REMARK   3  DATA USED IN REFINEMENT.                                            
REMARK   3   RESOLUTION RANGE HIGH (ANGSTROMS) : 3.30                           
REMARK   3   RESOLUTION RANGE LOW  (ANGSTROMS) : 20.00                          
REMARK   3   DATA CUTOFF            (SIGMA(F)) : 0.000                          
REMARK   3   DATA CUTOFF HIGH         (ABS(F)) : NULL                           
REMARK   3   DATA CUTOFF LOW          (ABS(F)) : NULL                           
REMARK   3   COMPLETENESS (WORKING+TEST)   (%) : 95.3                           
REMARK   3   NUMBER OF REFLECTIONS             : 195669                         
REMARK   3                                                                      
REMARK   3  FIT TO DATA USED IN REFINEMENT.                                     
REMARK   3   CROSS-VALIDATION METHOD          : THROUGHOUT                      
REMARK   3   FREE R VALUE TEST SET SELECTION  : RANDOM                          
REMARK   3   R VALUE            (WORKING SET) : 0.265                           
REMARK   3   FREE R VALUE                     : 0.298                           
REMARK   3   FREE R VALUE TEST SET SIZE   (%) : 2.000                           
REMARK   3   FREE R VALUE TEST SET COUNT      : 3914                            
REMARK   3   ESTIMATED ERROR OF FREE R VALUE  : 0.005                           
REMARK   3                                                                      
REMARK   3  FIT IN THE HIGHEST RESOLUTION BIN.                                  
REMARK   3   TOTAL NUMBER OF BINS USED           : 10                           
REMARK   3   BIN RESOLUTION RANGE HIGH       (A) : 3.30                         
REMARK   3   BIN RESOLUTION RANGE LOW        (A) : 3.42                         
REMARK   3   BIN COMPLETENESS (WORKING+TEST) (%) : 88.70                        
REMARK   3   REFLECTIONS IN BIN    (WORKING SET) : 17784                        
REMARK   3   BIN R VALUE           (WORKING SET) : 0.3990                       
REMARK   3   BIN FREE R VALUE                    : 0.3960                       
REMARK   3   BIN FREE R VALUE TEST SET SIZE  (%) : 1.90                         
REMARK   3   BIN FREE R VALUE TEST SET COUNT     : 342                          
REMARK   3   ESTIMATED ERROR OF BIN FREE R VALUE : 0.021                        
REMARK   3                                                                      
REMARK   3  NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT.                    
REMARK   3   PROTEIN ATOMS            : 73536                                   
REMARK   3   NUCLEIC ACID ATOMS       : 0                                       
REMARK   3   HETEROGEN ATOMS          : 380                                     
REMARK   3   SOLVENT ATOMS            : 0                                       
REMARK   3                                                                      
REMARK   3  B VALUES.                                                           
REMARK   3   FROM WILSON PLOT           (A**2) : 47.50                          
REMARK   3   MEAN B VALUE      (OVERALL, A**2) : 64.80                          
REMARK   3   OVERALL ANISOTROPIC B VALUE.                                       
REMARK   3    B11 (A**2) : NULL                                                 
REMARK   3    B22 (A**2) : NULL                                                 
REMARK   3    B33 (A**2) : NULL                                                 
REMARK   3    B12 (A**2) : NULL                                                 
REMARK   3    B13 (A**2) : NULL                                                 
REMARK   3    B23 (A**2) : NULL                                                 
REMARK   3                                                                      
REMARK   3  ESTIMATED COORDINATE ERROR.                                         
REMARK   3   ESD FROM LUZZATI PLOT        (A) : 0.51                            
REMARK   3   ESD FROM SIGMAA              (A) : 0.76                            
REMARK   3   LOW RESOLUTION CUTOFF        (A) : 7.00                            
REMARK   3                                                                      
REMARK   3  CROSS-VALIDATED ESTIMATED COORDINATE ERROR.                         
REMARK   3   ESD FROM C-V LUZZATI PLOT    (A) : 0.57                            
REMARK   3   ESD FROM C-V SIGMAA          (A) : 0.76                            
REMARK   3                                                                      
REMARK   3  RMS DEVIATIONS FROM IDEAL VALUES.                                   
REMARK   3   BOND LENGTHS                 (A) : 0.012                           
REMARK   3   BOND ANGLES            (DEGREES) : 1.630                           
REMARK   3   DIHEDRAL ANGLES        (DEGREES) : 23.10                           
REMARK   3   IMPROPER ANGLES        (DEGREES) : 1.100                           
REMARK   3                                                                      
REMARK   3  ISOTROPIC THERMAL MODEL : ISOTROPIC RESTRAINED                      
REMARK   3                                                                      
REMARK   3  ISOTROPIC THERMAL FACTOR RESTRAINTS.    RMS    SIGMA                
REMARK   3   MAIN-CHAIN BOND              (A**2) : NULL  ; NULL                 
REMARK   3   MAIN-CHAIN ANGLE             (A**2) : NULL  ; NULL                 
REMARK   3   SIDE-CHAIN BOND              (A**2) : NULL  ; NULL                 
REMARK   3   SIDE-CHAIN ANGLE             (A**2) : NULL  ; NULL                 
REMARK   3                                                                      
REMARK   3  BULK SOLVENT MODELING.                                              
REMARK   3   METHOD USED : NULL                                                 
REMARK   3   KSOL        : NULL                                                 
REMARK   3   BSOL        : NULL                                                 
REMARK   3                                                                      
REMARK   3  NCS MODEL : NULL                                                    
REMARK   3                                                                      
REMARK   3  NCS RESTRAINTS.                         RMS   SIGMA/WEIGHT          
REMARK   3   GROUP  1  POSITIONAL            (A) : NULL  ; NULL                 
REMARK   3   GROUP  1  B-FACTOR           (A**2) : NULL  ; NULL                 
REMARK   3                                                                      
REMARK   3  PARAMETER FILE  1  : NULL                                           
REMARK   3  TOPOLOGY FILE  1   : NULL                                           
REMARK   3                                                                      
REMARK   3  OTHER REFINEMENT REMARKS: THE NUMBER OF REFLECTIONS USED IN         
REMARK   3  REFINEMENT INCLUDED TWO DERIVATIVES AND FE-EDGE, AT LOWER           
REMARK   3  RESOLUTION, WERE MERGED IN SHARP DURING PHASING.                    
REMARK   4                                                                      
REMARK   4 2FUG COMPLIES WITH FORMAT V. 3.30, 13-JUL-11                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 31-JAN-06.                  
REMARK 100 THE DEPOSITION ID IS D_1000036325.                                   
REMARK 200                                                                      
REMARK 200 EXPERIMENTAL DETAILS                                                 
REMARK 200  EXPERIMENT TYPE                : X-RAY DIFFRACTION                  
REMARK 200  DATE OF DATA COLLECTION        : 07-NOV-04                          
REMARK 200  TEMPERATURE           (KELVIN) : 100                                
REMARK 200  PH                             : 7.5                                
REMARK 200  NUMBER OF CRYSTALS USED        : 1                                  
REMARK 200                                                                      
REMARK 200  SYNCHROTRON              (Y/N) : Y                                  
REMARK 200  RADIATION SOURCE               : ESRF                               
REMARK 200  BEAMLINE                       : ID29                               
REMARK 200  X-RAY GENERATOR MODEL          : NULL                               
REMARK 200  MONOCHROMATIC OR LAUE    (M/L) : M                                  
REMARK 200  WAVELENGTH OR RANGE        (A) : 0.97564                            
REMARK 200  MONOCHROMATOR                  : SI(311)                            
REMARK 200  OPTICS                         : NULL                               
REMARK 200                                                                      
REMARK 200  DETECTOR TYPE                  : CCD                                
REMARK 200  DETECTOR MANUFACTURER          : ADSC QUANTUM 210                   
REMARK 200  INTENSITY-INTEGRATION SOFTWARE : MOSFLM                             
REMARK 200  DATA SCALING SOFTWARE          : SCALA, CCP4 (SCALA)                
REMARK 200                                                                      
REMARK 200  NUMBER OF UNIQUE REFLECTIONS   : 195669                             
REMARK 200  RESOLUTION RANGE HIGH      (A) : 3.300                              
REMARK 200  RESOLUTION RANGE LOW       (A) : 29.988                             
REMARK 200  REJECTION CRITERIA  (SIGMA(I)) : 0.000                              
REMARK 200                                                                      
REMARK 200 OVERALL.                                                             
REMARK 200  COMPLETENESS FOR RANGE     (%) : 92.7                               
REMARK 200  DATA REDUNDANCY                : 3.200                              
REMARK 200  R MERGE                    (I) : 0.15800                            
REMARK 200  R SYM                      (I) : 0.15800                            
REMARK 200  <I/SIGMA(I)> FOR THE DATA SET  : 6.1000                             
REMARK 200                                                                      
REMARK 200 IN THE HIGHEST RESOLUTION SHELL.                                     
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 3.30                     
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE LOW  (A) : 3.48                     
REMARK 200  COMPLETENESS FOR SHELL     (%) : 89.2                               
REMARK 200  DATA REDUNDANCY IN SHELL       : 3.20                               
REMARK 200  R MERGE FOR SHELL          (I) : 0.55200                            
REMARK 200  R SYM FOR SHELL            (I) : 0.55200                            
REMARK 200  <I/SIGMA(I)> FOR SHELL         : 1.700                              
REMARK 200                                                                      
REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH                              
REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MIRAS                        
REMARK 200 SOFTWARE USED: SHARP                                                 
REMARK 200 STARTING MODEL: NULL                                                 
REMARK 200                                                                      
REMARK 200 REMARK: NULL                                                         
REMARK 280                                                                      
REMARK 280 CRYSTAL                                                              
REMARK 280 SOLVENT CONTENT, VS   (%): 60.52                                     
REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 3.12                     
REMARK 280                                                                      
REMARK 280 CRYSTALLIZATION CONDITIONS: 0.1M HEPES PH 7.5, 0.4-0.5M NACL, 0.1M   
REMARK 280  CACL2 AND 8-10% PEG4000, VAPOR DIFFUSION, SITTING DROP,             
REMARK 280  TEMPERATURE 295K                                                    
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY                                            
REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 1 21 1                         
REMARK 290                                                                      
REMARK 290      SYMOP   SYMMETRY                                                
REMARK 290     NNNMMM   OPERATOR                                                
REMARK 290       1555   X,Y,Z                                                   
REMARK 290       2555   -X,Y+1/2,-Z                                             
REMARK 290                                                                      
REMARK 290     WHERE NNN -> OPERATOR NUMBER                                     
REMARK 290           MMM -> TRANSLATION VECTOR                                  
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS                            
REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM             
REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY                
REMARK 290 RELATED MOLECULES.                                                   
REMARK 290   SMTRY1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY1   2 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   2  0.000000  1.000000  0.000000      133.05600            
REMARK 290   SMTRY3   2  0.000000  0.000000 -1.000000        0.00000            
REMARK 290                                                                      
REMARK 290 REMARK: NULL                                                         
REMARK 300                                                                      
REMARK 300 BIOMOLECULE: 1, 2, 3, 4                                              
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM                
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN                  
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON               
REMARK 300 BURIED SURFACE AREA.                                                 
REMARK 350                                                                      
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN           
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE                
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS          
REMARK 350 GIVEN BELOW.  BOTH NON-CRYSTALLOGRAPHIC AND                          
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.                               
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 1                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: OCTAMERIC                         
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: OCTAMERIC                  
REMARK 350 SOFTWARE USED: PISA                                                  
REMARK 350 TOTAL BURIED SURFACE AREA: 37440 ANGSTROM**2                         
REMARK 350 SURFACE AREA OF THE COMPLEX: 82540 ANGSTROM**2                       
REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -333.0 KCAL/MOL                       
REMARK 350 APPLY THE FOLLOWING TO CHAINS: 1, 2, 3, 4, 5, 6, 9, 7                
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 2                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: OCTAMERIC                         
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: OCTAMERIC                  
REMARK 350 SOFTWARE USED: PISA                                                  
REMARK 350 TOTAL BURIED SURFACE AREA: 37440 ANGSTROM**2                         
REMARK 350 SURFACE AREA OF THE COMPLEX: 82550 ANGSTROM**2                       
REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -334.0 KCAL/MOL                       
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B, C, D, E, F, G, H                
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 3                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: OCTAMERIC                         
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: OCTAMERIC                  
REMARK 350 SOFTWARE USED: PISA                                                  
REMARK 350 TOTAL BURIED SURFACE AREA: 37430 ANGSTROM**2                         
REMARK 350 SURFACE AREA OF THE COMPLEX: 82490 ANGSTROM**2                       
REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -328.0 KCAL/MOL                       
REMARK 350 APPLY THE FOLLOWING TO CHAINS: J, K, L, M, N, O, P, Q                
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 4                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: OCTAMERIC                         
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: OCTAMERIC                  
REMARK 350 SOFTWARE USED: PISA                                                  
REMARK 350 TOTAL BURIED SURFACE AREA: 37500 ANGSTROM**2                         
REMARK 350 SURFACE AREA OF THE COMPLEX: 82440 ANGSTROM**2                       
REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -334.0 KCAL/MOL                       
REMARK 350 APPLY THE FOLLOWING TO CHAINS: S, T, U, V, W, X, Y, Z                
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 465                                                                      
REMARK 465 MISSING RESIDUES                                                     
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE                       
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)                
REMARK 465                                                                      
REMARK 465   M RES C SSSEQI                                                     
REMARK 465     MET 1     1                                                      
REMARK 465     THR 1     2                                                      
REMARK 465     GLY 1     3                                                      
REMARK 465     PRO 1     4                                                      
REMARK 465     ILE 1     5                                                      
REMARK 465     LEU 1     6                                                      
REMARK 465     MET 2     1                                                      
REMARK 465     GLY 2     2                                                      
REMARK 465     VAL 2   181                                                      
REMARK 465     PRO 3    55                                                      
REMARK 465     LYS 3    56                                                      
REMARK 465     LYS 3    57                                                      
REMARK 465     GLY 3    58                                                      
REMARK 465     PRO 3    59                                                      
REMARK 465     ASP 3    60                                                      
REMARK 465     GLY 3    61                                                      
REMARK 465     LYS 3    62                                                      
REMARK 465     PRO 3    63                                                      
REMARK 465     LEU 3    64                                                      
REMARK 465     LEU 3    65                                                      
REMARK 465     ASN 3    66                                                      
REMARK 465     GLU 3    67                                                      
REMARK 465     LYS 3    68                                                      
REMARK 465     GLY 3    69                                                      
REMARK 465     GLU 3    70                                                      
REMARK 465     PRO 3    71                                                      
REMARK 465     GLU 3    72                                                      
REMARK 465     TYR 3   143                                                      
REMARK 465     TYR 3   144                                                      
REMARK 465     GLN 3   145                                                      
REMARK 465     LYS 3   146                                                      
REMARK 465     GLY 3   147                                                      
REMARK 465     PRO 3   148                                                      
REMARK 465     LEU 3   149                                                      
REMARK 465     GLU 3   150                                                      
REMARK 465     LYS 3   528                                                      
REMARK 465     GLY 3   529                                                      
REMARK 465     GLU 3   715                                                      
REMARK 465     LEU 3   716                                                      
REMARK 465     GLY 3   768                                                      
REMARK 465     LEU 3   769                                                      
REMARK 465     ARG 3   770                                                      
REMARK 465     VAL 3   771                                                      
REMARK 465     GLU 3   772                                                      
REMARK 465     GLY 3   773                                                      
REMARK 465     ARG 3   774                                                      
REMARK 465     VAL 3   775                                                      
REMARK 465     LEU 3   776                                                      
REMARK 465     VAL 3   777                                                      
REMARK 465     PRO 3   778                                                      
REMARK 465     ALA 3   779                                                      
REMARK 465     GLY 3   780                                                      
REMARK 465     GLY 3   781                                                      
REMARK 465     GLU 3   782                                                      
REMARK 465     ALA 3   783                                                      
REMARK 465     MET 4     1                                                      
REMARK 465     ARG 4     2                                                      
REMARK 465     GLU 4     3                                                      
REMARK 465     GLU 4     4                                                      
REMARK 465     PHE 4     5                                                      
REMARK 465     LEU 4     6                                                      
REMARK 465     GLU 4     7                                                      
REMARK 465     GLU 4     8                                                      
REMARK 465     ILE 4     9                                                      
REMARK 465     PRO 4    10                                                      
REMARK 465     LEU 4    11                                                      
REMARK 465     ASP 4    12                                                      
REMARK 465     ALA 4    13                                                      
REMARK 465     PRO 4    14                                                      
REMARK 465     PRO 4    15                                                      
REMARK 465     GLU 4    16                                                      
REMARK 465     GLU 4    17                                                      
REMARK 465     ALA 4    18                                                      
REMARK 465     LYS 4    19                                                      
REMARK 465     GLU 4    20                                                      
REMARK 465     LEU 4    21                                                      
REMARK 465     ARG 4    22                                                      
REMARK 465     THR 4    23                                                      
REMARK 465     GLU 4    24                                                      
REMARK 465     VAL 4    25                                                      
REMARK 465     MET 4    26                                                      
REMARK 465     THR 4    27                                                      
REMARK 465     LEU 4    28                                                      
REMARK 465     ASN 4    29                                                      
REMARK 465     VAL 4    30                                                      
REMARK 465     GLY 4    31                                                      
REMARK 465     PRO 4    32                                                      
REMARK 465     GLN 4    33                                                      
REMARK 465     HIS 4    34                                                      
REMARK 465     GLU 4   258                                                      
REMARK 465     THR 4   259                                                      
REMARK 465     TYR 4   260                                                      
REMARK 465     THR 4   261                                                      
REMARK 465     PHE 4   262                                                      
REMARK 465     LEU 5   107                                                      
REMARK 465     TRP 5   108                                                      
REMARK 465     GLY 5   109                                                      
REMARK 465     SER 5   110                                                      
REMARK 465     ALA 5   111                                                      
REMARK 465     ALA 5   197                                                      
REMARK 465     ASP 5   198                                                      
REMARK 465     LEU 5   199                                                      
REMARK 465     LYS 5   200                                                      
REMARK 465     LYS 5   201                                                      
REMARK 465     ALA 5   202                                                      
REMARK 465     ARG 5   203                                                      
REMARK 465     GLU 5   204                                                      
REMARK 465     VAL 5   205                                                      
REMARK 465     LYS 5   206                                                      
REMARK 465     GLY 5   207                                                      
REMARK 465     MET 6     1                                                      
REMARK 465     ALA 6     2                                                      
REMARK 465     LEU 6     3                                                      
REMARK 465     LYS 6     4                                                      
REMARK 465     ASP 6     5                                                      
REMARK 465     LEU 6     6                                                      
REMARK 465     PHE 6     7                                                      
REMARK 465     GLU 6     8                                                      
REMARK 465     ARG 6     9                                                      
REMARK 465     ASP 6    10                                                      
REMARK 465     VAL 6    11                                                      
REMARK 465     GLN 6    12                                                      
REMARK 465     GLU 6    13                                                      
REMARK 465     LEU 6    14                                                      
REMARK 465     ARG 6    57                                                      
REMARK 465     ASN 6    58                                                      
REMARK 465     ASP 6    59                                                      
REMARK 465     LEU 6    60                                                      
REMARK 465     ALA 6    61                                                      
REMARK 465     ARG 6    62                                                      
REMARK 465     PHE 6    63                                                      
REMARK 465     GLY 6    64                                                      
REMARK 465     SER 6    65                                                      
REMARK 465     GLU 6    66                                                      
REMARK 465     VAL 6    67                                                      
REMARK 465     PHE 6    68                                                      
REMARK 465     ARG 6    69                                                      
REMARK 465     ALA 6    70                                                      
REMARK 465     SER 6    71                                                      
REMARK 465     PRO 6    72                                                      
REMARK 465     ARG 6    73                                                      
REMARK 465     TRP 6   176                                                      
REMARK 465     LYS 6   177                                                      
REMARK 465     ARG 6   178                                                      
REMARK 465     THR 6   179                                                      
REMARK 465     ARG 6   180                                                      
REMARK 465     GLY 6   181                                                      
REMARK 465     MET 9     1                                                      
REMARK 465     THR 9     2                                                      
REMARK 465     LEU 9     3                                                      
REMARK 465     LYS 9     4                                                      
REMARK 465     ALA 9     5                                                      
REMARK 465     LEU 9     6                                                      
REMARK 465     ALA 9     7                                                      
REMARK 465     GLN 9     8                                                      
REMARK 465     SER 9     9                                                      
REMARK 465     LEU 9    10                                                      
REMARK 465     GLY 9    11                                                      
REMARK 465     ILE 9    12                                                      
REMARK 465     THR 9    13                                                      
REMARK 465     LEU 9    14                                                      
REMARK 465     LYS 9    15                                                      
REMARK 465     TYR 9    16                                                      
REMARK 465     LEU 9    17                                                      
REMARK 465     PHE 9    18                                                      
REMARK 465     SER 9    19                                                      
REMARK 465     LYS 9    20                                                      
REMARK 465     PRO 9    21                                                      
REMARK 465     VAL 9    22                                                      
REMARK 465     THR 9    23                                                      
REMARK 465     VAL 9    24                                                      
REMARK 465     PRO 9    25                                                      
REMARK 465     GLY 9   180                                                      
REMARK 465     LYS 9   181                                                      
REMARK 465     ARG 9   182                                                      
REMARK 465     MET 7     1                                                      
REMARK 465     SER 7     2                                                      
REMARK 465     MET A     1                                                      
REMARK 465     THR A     2                                                      
REMARK 465     GLY A     3                                                      
REMARK 465     PRO A     4                                                      
REMARK 465     ILE A     5                                                      
REMARK 465     LEU A     6                                                      
REMARK 465     MET B     1                                                      
REMARK 465     GLY B     2                                                      
REMARK 465     VAL B   181                                                      
REMARK 465     PRO C    55                                                      
REMARK 465     LYS C    56                                                      
REMARK 465     LYS C    57                                                      
REMARK 465     GLY C    58                                                      
REMARK 465     PRO C    59                                                      
REMARK 465     ASP C    60                                                      
REMARK 465     GLY C    61                                                      
REMARK 465     LYS C    62                                                      
REMARK 465     PRO C    63                                                      
REMARK 465     LEU C    64                                                      
REMARK 465     LEU C    65                                                      
REMARK 465     ASN C    66                                                      
REMARK 465     GLU C    67                                                      
REMARK 465     LYS C    68                                                      
REMARK 465     GLY C    69                                                      
REMARK 465     GLU C    70                                                      
REMARK 465     PRO C    71                                                      
REMARK 465     GLU C    72                                                      
REMARK 465     TYR C   143                                                      
REMARK 465     TYR C   144                                                      
REMARK 465     GLN C   145                                                      
REMARK 465     LYS C   146                                                      
REMARK 465     GLY C   147                                                      
REMARK 465     PRO C   148                                                      
REMARK 465     LEU C   149                                                      
REMARK 465     GLU C   150                                                      
REMARK 465     LYS C   528                                                      
REMARK 465     GLY C   529                                                      
REMARK 465     GLU C   715                                                      
REMARK 465     LEU C   716                                                      
REMARK 465     GLY C   768                                                      
REMARK 465     LEU C   769                                                      
REMARK 465     ARG C   770                                                      
REMARK 465     VAL C   771                                                      
REMARK 465     GLU C   772                                                      
REMARK 465     GLY C   773                                                      
REMARK 465     ARG C   774                                                      
REMARK 465     VAL C   775                                                      
REMARK 465     LEU C   776                                                      
REMARK 465     VAL C   777                                                      
REMARK 465     PRO C   778                                                      
REMARK 465     ALA C   779                                                      
REMARK 465     GLY C   780                                                      
REMARK 465     GLY C   781                                                      
REMARK 465     GLU C   782                                                      
REMARK 465     ALA C   783                                                      
REMARK 465     MET D     1                                                      
REMARK 465     ARG D     2                                                      
REMARK 465     GLU D     3                                                      
REMARK 465     GLU D     4                                                      
REMARK 465     PHE D     5                                                      
REMARK 465     LEU D     6                                                      
REMARK 465     GLU D     7                                                      
REMARK 465     GLU D     8                                                      
REMARK 465     ILE D     9                                                      
REMARK 465     PRO D    10                                                      
REMARK 465     LEU D    11                                                      
REMARK 465     ASP D    12                                                      
REMARK 465     ALA D    13                                                      
REMARK 465     PRO D    14                                                      
REMARK 465     PRO D    15                                                      
REMARK 465     GLU D    16                                                      
REMARK 465     GLU D    17                                                      
REMARK 465     ALA D    18                                                      
REMARK 465     LYS D    19                                                      
REMARK 465     GLU D    20                                                      
REMARK 465     LEU D    21                                                      
REMARK 465     ARG D    22                                                      
REMARK 465     THR D    23                                                      
REMARK 465     GLU D    24                                                      
REMARK 465     VAL D    25                                                      
REMARK 465     MET D    26                                                      
REMARK 465     THR D    27                                                      
REMARK 465     LEU D    28                                                      
REMARK 465     ASN D    29                                                      
REMARK 465     VAL D    30                                                      
REMARK 465     GLY D    31                                                      
REMARK 465     PRO D    32                                                      
REMARK 465     GLN D    33                                                      
REMARK 465     HIS D    34                                                      
REMARK 465     GLU D   258                                                      
REMARK 465     THR D   259                                                      
REMARK 465     TYR D   260                                                      
REMARK 465     THR D   261                                                      
REMARK 465     PHE D   262                                                      
REMARK 465     LEU E   107                                                      
REMARK 465     TRP E   108                                                      
REMARK 465     GLY E   109                                                      
REMARK 465     SER E   110                                                      
REMARK 465     ALA E   111                                                      
REMARK 465     ALA E   197                                                      
REMARK 465     ASP E   198                                                      
REMARK 465     LEU E   199                                                      
REMARK 465     LYS E   200                                                      
REMARK 465     LYS E   201                                                      
REMARK 465     ALA E   202                                                      
REMARK 465     ARG E   203                                                      
REMARK 465     GLU E   204                                                      
REMARK 465     VAL E   205                                                      
REMARK 465     LYS E   206                                                      
REMARK 465     GLY E   207                                                      
REMARK 465     MET F     1                                                      
REMARK 465     ALA F     2                                                      
REMARK 465     LEU F     3                                                      
REMARK 465     LYS F     4                                                      
REMARK 465     ASP F     5                                                      
REMARK 465     LEU F     6                                                      
REMARK 465     PHE F     7                                                      
REMARK 465     GLU F     8                                                      
REMARK 465     ARG F     9                                                      
REMARK 465     ASP F    10                                                      
REMARK 465     VAL F    11                                                      
REMARK 465     GLN F    12                                                      
REMARK 465     GLU F    13                                                      
REMARK 465     LEU F    14                                                      
REMARK 465     ARG F    57                                                      
REMARK 465     ASN F    58                                                      
REMARK 465     ASP F    59                                                      
REMARK 465     LEU F    60                                                      
REMARK 465     ALA F    61                                                      
REMARK 465     ARG F    62                                                      
REMARK 465     PHE F    63                                                      
REMARK 465     GLY F    64                                                      
REMARK 465     SER F    65                                                      
REMARK 465     GLU F    66                                                      
REMARK 465     VAL F    67                                                      
REMARK 465     PHE F    68                                                      
REMARK 465     ARG F    69                                                      
REMARK 465     ALA F    70                                                      
REMARK 465     SER F    71                                                      
REMARK 465     PRO F    72                                                      
REMARK 465     ARG F    73                                                      
REMARK 465     TRP F   176                                                      
REMARK 465     LYS F   177                                                      
REMARK 465     ARG F   178                                                      
REMARK 465     THR F   179                                                      
REMARK 465     ARG F   180                                                      
REMARK 465     GLY F   181                                                      
REMARK 465     MET G     1                                                      
REMARK 465     THR G     2                                                      
REMARK 465     LEU G     3                                                      
REMARK 465     LYS G     4                                                      
REMARK 465     ALA G     5                                                      
REMARK 465     LEU G     6                                                      
REMARK 465     ALA G     7                                                      
REMARK 465     GLN G     8                                                      
REMARK 465     SER G     9                                                      
REMARK 465     LEU G    10                                                      
REMARK 465     GLY G    11                                                      
REMARK 465     ILE G    12                                                      
REMARK 465     THR G    13                                                      
REMARK 465     LEU G    14                                                      
REMARK 465     LYS G    15                                                      
REMARK 465     TYR G    16                                                      
REMARK 465     LEU G    17                                                      
REMARK 465     PHE G    18                                                      
REMARK 465     SER G    19                                                      
REMARK 465     LYS G    20                                                      
REMARK 465     PRO G    21                                                      
REMARK 465     VAL G    22                                                      
REMARK 465     THR G    23                                                      
REMARK 465     VAL G    24                                                      
REMARK 465     PRO G    25                                                      
REMARK 465     GLY G   180                                                      
REMARK 465     LYS G   181                                                      
REMARK 465     ARG G   182                                                      
REMARK 465     MET H     1                                                      
REMARK 465     SER H     2                                                      
REMARK 465     MET J     1                                                      
REMARK 465     THR J     2                                                      
REMARK 465     GLY J     3                                                      
REMARK 465     PRO J     4                                                      
REMARK 465     ILE J     5                                                      
REMARK 465     LEU J     6                                                      
REMARK 465     MET K     1                                                      
REMARK 465     GLY K     2                                                      
REMARK 465     VAL K   181                                                      
REMARK 465     PRO L    55                                                      
REMARK 465     LYS L    56                                                      
REMARK 465     LYS L    57                                                      
REMARK 465     GLY L    58                                                      
REMARK 465     PRO L    59                                                      
REMARK 465     ASP L    60                                                      
REMARK 465     GLY L    61                                                      
REMARK 465     LYS L    62                                                      
REMARK 465     PRO L    63                                                      
REMARK 465     LEU L    64                                                      
REMARK 465     LEU L    65                                                      
REMARK 465     ASN L    66                                                      
REMARK 465     GLU L    67                                                      
REMARK 465     LYS L    68                                                      
REMARK 465     GLY L    69                                                      
REMARK 465     GLU L    70                                                      
REMARK 465     PRO L    71                                                      
REMARK 465     GLU L    72                                                      
REMARK 465     TYR L   143                                                      
REMARK 465     TYR L   144                                                      
REMARK 465     GLN L   145                                                      
REMARK 465     LYS L   146                                                      
REMARK 465     GLY L   147                                                      
REMARK 465     PRO L   148                                                      
REMARK 465     LEU L   149                                                      
REMARK 465     GLU L   150                                                      
REMARK 465     LYS L   528                                                      
REMARK 465     GLY L   529                                                      
REMARK 465     GLU L   715                                                      
REMARK 465     LEU L   716                                                      
REMARK 465     GLY L   768                                                      
REMARK 465     LEU L   769                                                      
REMARK 465     ARG L   770                                                      
REMARK 465     VAL L   771                                                      
REMARK 465     GLU L   772                                                      
REMARK 465     GLY L   773                                                      
REMARK 465     ARG L   774                                                      
REMARK 465     VAL L   775                                                      
REMARK 465     LEU L   776                                                      
REMARK 465     VAL L   777                                                      
REMARK 465     PRO L   778                                                      
REMARK 465     ALA L   779                                                      
REMARK 465     GLY L   780                                                      
REMARK 465     GLY L   781                                                      
REMARK 465     GLU L   782                                                      
REMARK 465     ALA L   783                                                      
REMARK 465     MET M     1                                                      
REMARK 465     ARG M     2                                                      
REMARK 465     GLU M     3                                                      
REMARK 465     GLU M     4                                                      
REMARK 465     PHE M     5                                                      
REMARK 465     LEU M     6                                                      
REMARK 465     GLU M     7                                                      
REMARK 465     GLU M     8                                                      
REMARK 465     ILE M     9                                                      
REMARK 465     PRO M    10                                                      
REMARK 465     LEU M    11                                                      
REMARK 465     ASP M    12                                                      
REMARK 465     ALA M    13                                                      
REMARK 465     PRO M    14                                                      
REMARK 465     PRO M    15                                                      
REMARK 465     GLU M    16                                                      
REMARK 465     GLU M    17                                                      
REMARK 465     ALA M    18                                                      
REMARK 465     LYS M    19                                                      
REMARK 465     GLU M    20                                                      
REMARK 465     LEU M    21                                                      
REMARK 465     ARG M    22                                                      
REMARK 465     THR M    23                                                      
REMARK 465     GLU M    24                                                      
REMARK 465     VAL M    25                                                      
REMARK 465     MET M    26                                                      
REMARK 465     THR M    27                                                      
REMARK 465     LEU M    28                                                      
REMARK 465     ASN M    29                                                      
REMARK 465     VAL M    30                                                      
REMARK 465     GLY M    31                                                      
REMARK 465     PRO M    32                                                      
REMARK 465     GLN M    33                                                      
REMARK 465     HIS M    34                                                      
REMARK 465     GLU M   258                                                      
REMARK 465     THR M   259                                                      
REMARK 465     TYR M   260                                                      
REMARK 465     THR M   261                                                      
REMARK 465     PHE M   262                                                      
REMARK 465     LEU N   107                                                      
REMARK 465     TRP N   108                                                      
REMARK 465     GLY N   109                                                      
REMARK 465     SER N   110                                                      
REMARK 465     ALA N   111                                                      
REMARK 465     ALA N   197                                                      
REMARK 465     ASP N   198                                                      
REMARK 465     LEU N   199                                                      
REMARK 465     LYS N   200                                                      
REMARK 465     LYS N   201                                                      
REMARK 465     ALA N   202                                                      
REMARK 465     ARG N   203                                                      
REMARK 465     GLU N   204                                                      
REMARK 465     VAL N   205                                                      
REMARK 465     LYS N   206                                                      
REMARK 465     GLY N   207                                                      
REMARK 465     MET O     1                                                      
REMARK 465     ALA O     2                                                      
REMARK 465     LEU O     3                                                      
REMARK 465     LYS O     4                                                      
REMARK 465     ASP O     5                                                      
REMARK 465     LEU O     6                                                      
REMARK 465     PHE O     7                                                      
REMARK 465     GLU O     8                                                      
REMARK 465     ARG O     9                                                      
REMARK 465     ASP O    10                                                      
REMARK 465     VAL O    11                                                      
REMARK 465     GLN O    12                                                      
REMARK 465     GLU O    13                                                      
REMARK 465     LEU O    14                                                      
REMARK 465     ARG O    57                                                      
REMARK 465     ASN O    58                                                      
REMARK 465     ASP O    59                                                      
REMARK 465     LEU O    60                                                      
REMARK 465     ALA O    61                                                      
REMARK 465     ARG O    62                                                      
REMARK 465     PHE O    63                                                      
REMARK 465     GLY O    64                                                      
REMARK 465     SER O    65                                                      
REMARK 465     GLU O    66                                                      
REMARK 465     VAL O    67                                                      
REMARK 465     PHE O    68                                                      
REMARK 465     ARG O    69                                                      
REMARK 465     ALA O    70                                                      
REMARK 465     SER O    71                                                      
REMARK 465     PRO O    72                                                      
REMARK 465     ARG O    73                                                      
REMARK 465     TRP O   176                                                      
REMARK 465     LYS O   177                                                      
REMARK 465     ARG O   178                                                      
REMARK 465     THR O   179                                                      
REMARK 465     ARG O   180                                                      
REMARK 465     GLY O   181                                                      
REMARK 465     MET P     1                                                      
REMARK 465     THR P     2                                                      
REMARK 465     LEU P     3                                                      
REMARK 465     LYS P     4                                                      
REMARK 465     ALA P     5                                                      
REMARK 465     LEU P     6                                                      
REMARK 465     ALA P     7                                                      
REMARK 465     GLN P     8                                                      
REMARK 465     SER P     9                                                      
REMARK 465     LEU P    10                                                      
REMARK 465     GLY P    11                                                      
REMARK 465     ILE P    12                                                      
REMARK 465     THR P    13                                                      
REMARK 465     LEU P    14                                                      
REMARK 465     LYS P    15                                                      
REMARK 465     TYR P    16                                                      
REMARK 465     LEU P    17                                                      
REMARK 465     PHE P    18                                                      
REMARK 465     SER P    19                                                      
REMARK 465     LYS P    20                                                      
REMARK 465     PRO P    21                                                      
REMARK 465     VAL P    22                                                      
REMARK 465     THR P    23                                                      
REMARK 465     VAL P    24                                                      
REMARK 465     PRO P    25                                                      
REMARK 465     GLY P   180                                                      
REMARK 465     LYS P   181                                                      
REMARK 465     ARG P   182                                                      
REMARK 465     MET Q     1                                                      
REMARK 465     SER Q     2                                                      
REMARK 465     MET S     1                                                      
REMARK 465     THR S     2                                                      
REMARK 465     GLY S     3                                                      
REMARK 465     PRO S     4                                                      
REMARK 465     ILE S     5                                                      
REMARK 465     LEU S     6                                                      
REMARK 465     MET T     1                                                      
REMARK 465     GLY T     2                                                      
REMARK 465     VAL T   181                                                      
REMARK 465     PRO U    55                                                      
REMARK 465     LYS U    56                                                      
REMARK 465     LYS U    57                                                      
REMARK 465     GLY U    58                                                      
REMARK 465     PRO U    59                                                      
REMARK 465     ASP U    60                                                      
REMARK 465     GLY U    61                                                      
REMARK 465     LYS U    62                                                      
REMARK 465     PRO U    63                                                      
REMARK 465     LEU U    64                                                      
REMARK 465     LEU U    65                                                      
REMARK 465     ASN U    66                                                      
REMARK 465     GLU U    67                                                      
REMARK 465     LYS U    68                                                      
REMARK 465     GLY U    69                                                      
REMARK 465     GLU U    70                                                      
REMARK 465     PRO U    71                                                      
REMARK 465     GLU U    72                                                      
REMARK 465     TYR U   143                                                      
REMARK 465     TYR U   144                                                      
REMARK 465     GLN U   145                                                      
REMARK 465     LYS U   146                                                      
REMARK 465     GLY U   147                                                      
REMARK 465     PRO U   148                                                      
REMARK 465     LEU U   149                                                      
REMARK 465     GLU U   150                                                      
REMARK 465     LYS U   528                                                      
REMARK 465     GLY U   529                                                      
REMARK 465     GLU U   715                                                      
REMARK 465     LEU U   716                                                      
REMARK 465     GLY U   768                                                      
REMARK 465     LEU U   769                                                      
REMARK 465     ARG U   770                                                      
REMARK 465     VAL U   771                                                      
REMARK 465     GLU U   772                                                      
REMARK 465     GLY U   773                                                      
REMARK 465     ARG U   774                                                      
REMARK 465     VAL U   775                                                      
REMARK 465     LEU U   776                                                      
REMARK 465     VAL U   777                                                      
REMARK 465     PRO U   778                                                      
REMARK 465     ALA U   779                                                      
REMARK 465     GLY U   780                                                      
REMARK 465     GLY U   781                                                      
REMARK 465     GLU U   782                                                      
REMARK 465     ALA U   783                                                      
REMARK 465     MET V     1                                                      
REMARK 465     ARG V     2                                                      
REMARK 465     GLU V     3                                                      
REMARK 465     GLU V     4                                                      
REMARK 465     PHE V     5                                                      
REMARK 465     LEU V     6                                                      
REMARK 465     GLU V     7                                                      
REMARK 465     GLU V     8                                                      
REMARK 465     ILE V     9                                                      
REMARK 465     PRO V    10                                                      
REMARK 465     LEU V    11                                                      
REMARK 465     ASP V    12                                                      
REMARK 465     ALA V    13                                                      
REMARK 465     PRO V    14                                                      
REMARK 465     PRO V    15                                                      
REMARK 465     GLU V    16                                                      
REMARK 465     GLU V    17                                                      
REMARK 465     ALA V    18                                                      
REMARK 465     LYS V    19                                                      
REMARK 465     GLU V    20                                                      
REMARK 465     LEU V    21                                                      
REMARK 465     ARG V    22                                                      
REMARK 465     THR V    23                                                      
REMARK 465     GLU V    24                                                      
REMARK 465     VAL V    25                                                      
REMARK 465     MET V    26                                                      
REMARK 465     THR V    27                                                      
REMARK 465     LEU V    28                                                      
REMARK 465     ASN V    29                                                      
REMARK 465     VAL V    30                                                      
REMARK 465     GLY V    31                                                      
REMARK 465     PRO V    32                                                      
REMARK 465     GLN V    33                                                      
REMARK 465     HIS V    34                                                      
REMARK 465     GLU V   258                                                      
REMARK 465     THR V   259                                                      
REMARK 465     TYR V   260                                                      
REMARK 465     THR V   261                                                      
REMARK 465     PHE V   262                                                      
REMARK 465     LEU W   107                                                      
REMARK 465     TRP W   108                                                      
REMARK 465     GLY W   109                                                      
REMARK 465     SER W   110                                                      
REMARK 465     ALA W   111                                                      
REMARK 465     ALA W   197                                                      
REMARK 465     ASP W   198                                                      
REMARK 465     LEU W   199                                                      
REMARK 465     LYS W   200                                                      
REMARK 465     LYS W   201                                                      
REMARK 465     ALA W   202                                                      
REMARK 465     ARG W   203                                                      
REMARK 465     GLU W   204                                                      
REMARK 465     VAL W   205                                                      
REMARK 465     LYS W   206                                                      
REMARK 465     GLY W   207                                                      
REMARK 465     MET X     1                                                      
REMARK 465     ALA X     2                                                      
REMARK 465     LEU X     3                                                      
REMARK 465     LYS X     4                                                      
REMARK 465     ASP X     5                                                      
REMARK 465     LEU X     6                                                      
REMARK 465     PHE X     7                                                      
REMARK 465     GLU X     8                                                      
REMARK 465     ARG X     9                                                      
REMARK 465     ASP X    10                                                      
REMARK 465     VAL X    11                                                      
REMARK 465     GLN X    12                                                      
REMARK 465     GLU X    13                                                      
REMARK 465     LEU X    14                                                      
REMARK 465     ARG X    57                                                      
REMARK 465     ASN X    58                                                      
REMARK 465     ASP X    59                                                      
REMARK 465     LEU X    60                                                      
REMARK 465     ALA X    61                                                      
REMARK 465     ARG X    62                                                      
REMARK 465     PHE X    63                                                      
REMARK 465     GLY X    64                                                      
REMARK 465     SER X    65                                                      
REMARK 465     GLU X    66                                                      
REMARK 465     VAL X    67                                                      
REMARK 465     PHE X    68                                                      
REMARK 465     ARG X    69                                                      
REMARK 465     ALA X    70                                                      
REMARK 465     SER X    71                                                      
REMARK 465     PRO X    72                                                      
REMARK 465     ARG X    73                                                      
REMARK 465     TRP X   176                                                      
REMARK 465     LYS X   177                                                      
REMARK 465     ARG X   178                                                      
REMARK 465     THR X   179                                                      
REMARK 465     ARG X   180                                                      
REMARK 465     GLY X   181                                                      
REMARK 465     MET Y     1                                                      
REMARK 465     THR Y     2                                                      
REMARK 465     LEU Y     3                                                      
REMARK 465     LYS Y     4                                                      
REMARK 465     ALA Y     5                                                      
REMARK 465     LEU Y     6                                                      
REMARK 465     ALA Y     7                                                      
REMARK 465     GLN Y     8                                                      
REMARK 465     SER Y     9                                                      
REMARK 465     LEU Y    10                                                      
REMARK 465     GLY Y    11                                                      
REMARK 465     ILE Y    12                                                      
REMARK 465     THR Y    13                                                      
REMARK 465     LEU Y    14                                                      
REMARK 465     LYS Y    15                                                      
REMARK 465     TYR Y    16                                                      
REMARK 465     LEU Y    17                                                      
REMARK 465     PHE Y    18                                                      
REMARK 465     SER Y    19                                                      
REMARK 465     LYS Y    20                                                      
REMARK 465     PRO Y    21                                                      
REMARK 465     VAL Y    22                                                      
REMARK 465     THR Y    23                                                      
REMARK 465     VAL Y    24                                                      
REMARK 465     PRO Y    25                                                      
REMARK 465     GLY Y   180                                                      
REMARK 465     LYS Y   181                                                      
REMARK 465     ARG Y   182                                                      
REMARK 465     MET Z     1                                                      
REMARK 465     SER Z     2                                                      
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT                     
REMARK 500                                                                      
REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT.                            
REMARK 500                                                                      
REMARK 500  ATM1  RES C  SSEQI   ATM2  RES C  SSEQI           DISTANCE          
REMARK 500   O    VAL 3   282     O    ASN 3   286              2.11            
REMARK 500   O    ARG 3   178     N    ARG 3   180              2.11            
REMARK 500   O    VAL L   282     O    ASN L   286              2.12            
REMARK 500   O    ARG L   178     N    ARG L   180              2.14            
REMARK 500   O    ARG C   178     N    ARG C   180              2.14            
REMARK 500   O    ASP M    86     N    LEU M    88              2.15            
REMARK 500   O    ARG U   178     N    ARG U   180              2.15            
REMARK 500   O    VAL U   282     O    ASN U   286              2.16            
REMARK 500   O    PHE 5    46     N    PHE 5    48              2.18            
REMARK 500   O    PHE N    46     N    PHE N    48              2.19            
REMARK 500   O    TYR M   383     N    LYS M   386              2.19            
REMARK 500   O    PHE E    46     N    PHE E    48              2.19            
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: CLOSE CONTACTS                                             
REMARK 500                                                                      
REMARK 500 THE FOLLOWING ATOMS THAT ARE RELATED BY CRYSTALLOGRAPHIC             
REMARK 500 SYMMETRY ARE IN CLOSE CONTACT.  AN ATOM LOCATED WITHIN 0.15          
REMARK 500 ANGSTROMS OF A SYMMETRY RELATED ATOM IS ASSUMED TO BE ON A           
REMARK 500 SPECIAL POSITION AND IS, THEREFORE, LISTED IN REMARK 375             
REMARK 500 INSTEAD OF REMARK 500.  ATOMS WITH NON-BLANK ALTERNATE               
REMARK 500 LOCATION INDICATORS ARE NOT INCLUDED IN THE CALCULATIONS.            
REMARK 500                                                                      
REMARK 500 DISTANCE CUTOFF:                                                     
REMARK 500 2.2 ANGSTROMS FOR CONTACTS NOT INVOLVING HYDROGEN ATOMS              
REMARK 500 1.6 ANGSTROMS FOR CONTACTS INVOLVING HYDROGEN ATOMS                  
REMARK 500                                                                      
REMARK 500  ATM1  RES C  SSEQI   ATM2  RES C  SSEQI  SSYMOP   DISTANCE          
REMARK 500   N    MET L     1     OE2  GLU U   498     2645     2.01            
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: COVALENT BOND LENGTHS                                      
REMARK 500                                                                      
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES              
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE               
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                 
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT: (10X,I3,1X,2(A3,1X,A1,I4,A1,1X,A4,3X),1X,F6.3)               
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999                        
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996                     
REMARK 500                                                                      
REMARK 500  M RES CSSEQI ATM1   RES CSSEQI ATM2   DEVIATION                     
REMARK 500    CYS C 181   CB    CYS C 181   SG      0.129                       
REMARK 500    CYS J 356   CB    CYS J 356   SG     -0.103                       
REMARK 500    CYS L 181   CB    CYS L 181   SG      0.103                       
REMARK 500    CYS U 181   CB    CYS U 181   SG      0.108                       
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES                                       
REMARK 500                                                                      
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES              
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE               
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                 
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)              
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999                        
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996                     
REMARK 500                                                                      
REMARK 500  M RES CSSEQI ATM1   ATM2   ATM3                                     
REMARK 500    PRO 1 310   C   -  N   -  CA  ANGL. DEV. =   9.2 DEGREES          
REMARK 500    PRO 1 332   C   -  N   -  CA  ANGL. DEV. =  10.0 DEGREES          
REMARK 500    CYS 1 359   CA  -  CB  -  SG  ANGL. DEV. =   7.8 DEGREES          
REMARK 500    CYS 3 181   CA  -  CB  -  SG  ANGL. DEV. =  10.0 DEGREES          
REMARK 500    ILE 3 211   N   -  CA  -  C   ANGL. DEV. =  16.3 DEGREES          
REMARK 500    PHE 3 216   N   -  CA  -  C   ANGL. DEV. =  17.5 DEGREES          
REMARK 500    PRO 3 219   C   -  N   -  CA  ANGL. DEV. =  12.8 DEGREES          
REMARK 500    GLY 3 221   N   -  CA  -  C   ANGL. DEV. = -17.3 DEGREES          
REMARK 500    PRO 3 431   C   -  N   -  CA  ANGL. DEV. =   9.1 DEGREES          
REMARK 500    GLU 4 322   N   -  CA  -  C   ANGL. DEV. = -18.6 DEGREES          
REMARK 500    PRO 5  78   C   -  N   -  CA  ANGL. DEV. =  11.8 DEGREES          
REMARK 500    PRO 6 138   C   -  N   -  CA  ANGL. DEV. =  12.3 DEGREES          
REMARK 500    TYR 6 163   N   -  CA  -  C   ANGL. DEV. = -16.5 DEGREES          
REMARK 500    ASN 6 164   N   -  CA  -  C   ANGL. DEV. =  18.2 DEGREES          
REMARK 500    PRO A 332   C   -  N   -  CA  ANGL. DEV. =  11.5 DEGREES          
REMARK 500    CYS A 359   CA  -  CB  -  SG  ANGL. DEV. =   7.1 DEGREES          
REMARK 500    CYS C 181   CA  -  CB  -  SG  ANGL. DEV. =  10.1 DEGREES          
REMARK 500    ILE C 211   N   -  CA  -  C   ANGL. DEV. =  17.1 DEGREES          
REMARK 500    PHE C 216   N   -  CA  -  C   ANGL. DEV. =  16.5 DEGREES          
REMARK 500    PRO C 219   C   -  N   -  CA  ANGL. DEV. =  11.8 DEGREES          
REMARK 500    GLY C 221   N   -  CA  -  C   ANGL. DEV. = -18.3 DEGREES          
REMARK 500    PRO C 283   C   -  N   -  CA  ANGL. DEV. =   9.4 DEGREES          
REMARK 500    GLU D 322   N   -  CA  -  C   ANGL. DEV. = -18.7 DEGREES          
REMARK 500    PRO E  78   C   -  N   -  CA  ANGL. DEV. =  11.2 DEGREES          
REMARK 500    PRO F 138   C   -  N   -  CA  ANGL. DEV. =  11.1 DEGREES          
REMARK 500    ASN F 164   N   -  CA  -  C   ANGL. DEV. =  18.5 DEGREES          
REMARK 500    PRO J 332   C   -  N   -  CA  ANGL. DEV. =  11.2 DEGREES          
REMARK 500    CYS J 359   CA  -  CB  -  SG  ANGL. DEV. =   8.1 DEGREES          
REMARK 500    CYS L 181   CA  -  CB  -  SG  ANGL. DEV. =   9.3 DEGREES          
REMARK 500    ILE L 211   N   -  CA  -  C   ANGL. DEV. =  16.6 DEGREES          
REMARK 500    PHE L 216   N   -  CA  -  C   ANGL. DEV. =  17.3 DEGREES          
REMARK 500    PRO L 219   C   -  N   -  CA  ANGL. DEV. =  11.5 DEGREES          
REMARK 500    GLY L 221   N   -  CA  -  C   ANGL. DEV. = -18.0 DEGREES          
REMARK 500    PRO M 225   C   -  N   -  CD  ANGL. DEV. = -12.7 DEGREES          
REMARK 500    SER M 238   N   -  CA  -  C   ANGL. DEV. = -16.8 DEGREES          
REMARK 500    GLU M 322   N   -  CA  -  C   ANGL. DEV. = -18.5 DEGREES          
REMARK 500    PRO N  78   C   -  N   -  CA  ANGL. DEV. =  11.6 DEGREES          
REMARK 500    PRO O 138   C   -  N   -  CA  ANGL. DEV. =  11.6 DEGREES          
REMARK 500    TYR O 163   N   -  CA  -  C   ANGL. DEV. = -17.0 DEGREES          
REMARK 500    ASN O 164   N   -  CA  -  C   ANGL. DEV. =  18.4 DEGREES          
REMARK 500    PRO S 332   C   -  N   -  CA  ANGL. DEV. =   9.9 DEGREES          
REMARK 500    CYS S 359   CA  -  CB  -  SG  ANGL. DEV. =   8.0 DEGREES          
REMARK 500    PRO U  15   C   -  N   -  CA  ANGL. DEV. =   9.2 DEGREES          
REMARK 500    CYS U 181   CA  -  CB  -  SG  ANGL. DEV. =   8.9 DEGREES          
REMARK 500    ILE U 211   N   -  CA  -  C   ANGL. DEV. =  16.6 DEGREES          
REMARK 500    PHE U 216   N   -  CA  -  C   ANGL. DEV. =  17.0 DEGREES          
REMARK 500    PRO U 219   C   -  N   -  CA  ANGL. DEV. =  11.2 DEGREES          
REMARK 500    GLY U 221   N   -  CA  -  C   ANGL. DEV. = -18.9 DEGREES          
REMARK 500    PRO U 283   C   -  N   -  CA  ANGL. DEV. =  10.1 DEGREES          
REMARK 500    PRO V 212   C   -  N   -  CA  ANGL. DEV. =   9.1 DEGREES          
REMARK 500                                                                      
REMARK 500 THIS ENTRY HAS      55 ANGLE DEVIATIONS.                             
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: TORSION ANGLES                                             
REMARK 500                                                                      
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:            
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)                    
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-           
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400            
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        PSI       PHI                                   
REMARK 500    ASP 1  10     -161.45   -129.42                                   
REMARK 500    GLU 1  14      -62.58      8.97                                   
REMARK 500    LEU 1  17       84.40     63.98                                   
REMARK 500    HIS 1  20     -105.65    -85.14                                   
REMARK 500    VAL 1  21       72.80    -59.05                                   
REMARK 500    SER 1  26     -167.05   -170.68                                   
REMARK 500    TRP 1  27      -16.51   -170.60                                   
REMARK 500    THR 1  28      173.46    -44.16                                   
REMARK 500    TYR 1  38       25.75    -77.83                                   
REMARK 500    ARG 1  43      -72.77    -50.41                                   
REMARK 500    PRO 1  71       88.93    -54.03                                   
REMARK 500    LYS 1  81      -87.01   -101.33                                   
REMARK 500    ASP 1  83      -16.85   -152.52                                   
REMARK 500    GLU 1  95       92.44    -18.59                                   
REMARK 500    PHE 1 101       43.69   -160.05                                   
REMARK 500    VAL 1 110       34.54   -144.95                                   
REMARK 500    GLU 1 146      -74.67    -55.73                                   
REMARK 500    ARG 1 155       -0.90    -58.23                                   
REMARK 500    LYS 1 160      -94.87    -24.63                                   
REMARK 500    PHE 1 163       27.79     47.94                                   
REMARK 500    ASP 1 166       34.26     25.38                                   
REMARK 500    PHE 1 169      123.67   -170.03                                   
REMARK 500    ALA 1 177       38.72   -157.92                                   
REMARK 500    CYS 1 182      -10.42    -46.96                                   
REMARK 500    ALA 1 197       60.77    -66.86                                   
REMARK 500    SER 1 209      101.20   -169.55                                   
REMARK 500    LEU 1 211      108.31    -28.87                                   
REMARK 500    PRO 1 215      104.94    -53.36                                   
REMARK 500    VAL 1 221      -73.80    -34.56                                   
REMARK 500    MET 1 241      106.47   -171.05                                   
REMARK 500    THR 1 243     -156.71    -69.81                                   
REMARK 500    PRO 1 257       58.18    -60.48                                   
REMARK 500    MET 1 268      108.79    -46.46                                   
REMARK 500    TYR 1 277      -66.87   -100.90                                   
REMARK 500    SER 1 296       20.55    -62.18                                   
REMARK 500    MET 1 311       87.05    -65.94                                   
REMARK 500    TYR 1 313       29.04    -65.07                                   
REMARK 500    GLU 1 314      -57.06   -148.64                                   
REMARK 500    SER 1 321     -141.48    -95.02                                   
REMARK 500    PRO 1 358      -78.75    -59.27                                   
REMARK 500    PHE 1 366      -85.03    -71.56                                   
REMARK 500    MET 1 367      -71.57    -25.71                                   
REMARK 500    LYS 1 373      -75.96    -63.79                                   
REMARK 500    ARG 1 433       77.45   -112.89                                   
REMARK 500    LYS 2   7       65.39   -100.73                                   
REMARK 500    PRO 2  19      177.84    -59.85                                   
REMARK 500    GLN 2  35      -71.37    -48.89                                   
REMARK 500    TRP 2  40      138.20    165.76                                   
REMARK 500    THR 2  55     -166.51   -164.95                                   
REMARK 500    LEU 2  86      -80.40    -26.56                                   
REMARK 500                                                                      
REMARK 500 THIS ENTRY HAS    1182 RAMACHANDRAN OUTLIERS.                        
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: PLANAR GROUPS                                              
REMARK 500                                                                      
REMARK 500 PLANAR GROUPS IN THE FOLLOWING RESIDUES HAVE A TOTAL                 
REMARK 500 RMS DISTANCE OF ALL ATOMS FROM THE BEST-FIT PLANE                    
REMARK 500 BY MORE THAN AN EXPECTED VALUE OF 6*RMSD, WITH AN                    
REMARK 500 RMSD 0.02 ANGSTROMS, OR AT LEAST ONE ATOM HAS                        
REMARK 500 AN RMSD GREATER THAN THIS VALUE                                      
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        RMS     TYPE                                    
REMARK 500    TYR 9  69         0.07    SIDE CHAIN                              
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 620                                                                      
REMARK 620 METAL COORDINATION                                                   
REMARK 620 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 620 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE):                             
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 6 182  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 6 140   SG                                                     
REMARK 620 2 SF4 6 182   S2  113.6                                              
REMARK 620 3 SF4 6 182   S3  117.8 105.1                                        
REMARK 620 4 SF4 6 182   S4  110.1 103.7 105.3                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 6 182  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 6  46   SG                                                     
REMARK 620 2 SF4 6 182   S1  116.2                                              
REMARK 620 3 SF4 6 182   S3  113.3 106.2                                        
REMARK 620 4 SF4 6 182   S4  112.3 103.7 104.0                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 6 182  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 6 111   SG                                                     
REMARK 620 2 SF4 6 182   S1  119.6                                              
REMARK 620 3 SF4 6 182   S2  111.6 104.8                                        
REMARK 620 4 SF4 6 182   S4  109.6 105.1 105.0                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 6 182  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 6  45   SG                                                     
REMARK 620 2 SF4 6 182   S1  110.3                                              
REMARK 620 3 SF4 6 182   S2  119.6 105.0                                        
REMARK 620 4 SF4 6 182   S3  111.0 105.2 104.6                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 9 183  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 9  63   SG                                                     
REMARK 620 2 SF4 9 183   S2  111.7                                              
REMARK 620 3 SF4 9 183   S3  119.8 104.0                                        
REMARK 620 4 SF4 9 183   S4  111.8 103.3 104.6                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 9 183  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 9  98   SG                                                     
REMARK 620 2 SF4 9 183   S1  114.8                                              
REMARK 620 3 SF4 9 183   S3  117.9 103.5                                        
REMARK 620 4 SF4 9 183   S4  111.0 104.5 103.8                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 9 183  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 9 101   SG                                                     
REMARK 620 2 SF4 9 183   S1  121.5                                              
REMARK 620 3 SF4 9 183   S2  109.9 103.8                                        
REMARK 620 4 SF4 9 183   S4  112.0 103.2 105.1                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 9 183  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 9 104   SG                                                     
REMARK 620 2 SF4 9 183   S1  113.4                                              
REMARK 620 3 SF4 9 183   S2  112.5 105.2                                        
REMARK 620 4 SF4 9 183   S3  114.8 105.6 104.5                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 9 184  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 9  56   SG                                                     
REMARK 620 2 SF4 9 184   S2  117.3                                              
REMARK 620 3 SF4 9 184   S3  117.7 105.2                                        
REMARK 620 4 SF4 9 184   S4  106.1 105.3 103.8                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 9 184  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 9  59   SG                                                     
REMARK 620 2 SF4 9 184   S1  117.6                                              
REMARK 620 3 SF4 9 184   S3  117.0 104.4                                        
REMARK 620 4 SF4 9 184   S4  107.2 105.0 104.3                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 9 184  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 9 108   SG                                                     
REMARK 620 2 SF4 9 184   S1  119.2                                              
REMARK 620 3 SF4 9 184   S2  111.3 105.4                                        
REMARK 620 4 SF4 9 184   S4  111.6 103.3 104.9                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 9 184  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 9  53   SG                                                     
REMARK 620 2 SF4 9 184   S1  114.9                                              
REMARK 620 3 SF4 9 184   S2  109.1 106.3                                        
REMARK 620 4 SF4 9 184   S3  116.9 103.3 105.5                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 3 784  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 3 122   SG                                                     
REMARK 620 2 SF4 3 784   S2  116.7                                              
REMARK 620 3 SF4 3 784   S3  113.4 106.7                                        
REMARK 620 4 SF4 3 784   S4  111.1 103.9 103.9                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 3 784  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 3 119   SG                                                     
REMARK 620 2 SF4 3 784   S1  112.0                                              
REMARK 620 3 SF4 3 784   S3  113.0 105.1                                        
REMARK 620 4 SF4 3 784   S4  117.0 104.3 104.5                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 3 784  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 3 128   SG                                                     
REMARK 620 2 SF4 3 784   S1  113.2                                              
REMARK 620 3 SF4 3 784   S2  113.4 106.0                                        
REMARK 620 4 SF4 3 784   S4  115.1 103.6 104.5                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 3 784  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 HIS 3 115   NE2                                                    
REMARK 620 2 SF4 3 784   S1  107.3                                              
REMARK 620 3 SF4 3 784   S2  114.1 105.1                                        
REMARK 620 4 SF4 3 784   S3  120.1 104.5 104.4                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 3 785  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 3 230   SG                                                     
REMARK 620 2 SF4 3 785   S2  113.0                                              
REMARK 620 3 SF4 3 785   S3  118.6 105.5                                        
REMARK 620 4 SF4 3 785   S4  110.9 102.9 104.6                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 3 785  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 3 181   SG                                                     
REMARK 620 2 SF4 3 785   S1  122.6                                              
REMARK 620 3 SF4 3 785   S3  112.4 106.0                                        
REMARK 620 4 SF4 3 785   S4  106.0 103.1 105.0                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 3 785  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 3 184   SG                                                     
REMARK 620 2 SF4 3 785   S1  118.5                                              
REMARK 620 3 SF4 3 785   S2  102.7 105.8                                        
REMARK 620 4 SF4 3 785   S4  120.9 102.7 104.6                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 3 785  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 3 187   SG                                                     
REMARK 620 2 SF4 3 785   S1  115.6                                              
REMARK 620 3 SF4 3 785   S2  108.6 104.5                                        
REMARK 620 4 SF4 3 785   S3  117.7 103.5 105.7                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 3 786  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 3 259   SG                                                     
REMARK 620 2 SF4 3 786   S2  109.4                                              
REMARK 620 3 SF4 3 786   S3  114.3 104.6                                        
REMARK 620 4 SF4 3 786   S4  118.8 105.5 103.0                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 3 786  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 3 291   SG                                                     
REMARK 620 2 SF4 3 786   S1  113.0                                              
REMARK 620 3 SF4 3 786   S3  116.7 104.5                                        
REMARK 620 4 SF4 3 786   S4  110.8 106.3 104.7                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 3 786  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 3 256   SG                                                     
REMARK 620 2 SF4 3 786   S1  115.3                                              
REMARK 620 3 SF4 3 786   S2  110.4 104.8                                        
REMARK 620 4 SF4 3 786   S4  115.9 104.3 105.0                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 3 786  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 3 263   SG                                                     
REMARK 620 2 SF4 3 786   S1  118.7                                              
REMARK 620 3 SF4 3 786   S2  105.0 107.6                                        
REMARK 620 4 SF4 3 786   S3  116.5 102.7 105.4                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             FES 3 787  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 3  45   SG                                                     
REMARK 620 2 FES 3 787   S1  110.6                                              
REMARK 620 3 FES 3 787   S2  111.0 105.7                                        
REMARK 620 4 CYS 3  34   SG  108.6 117.4 103.3                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             FES 3 787  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 3  83   SG                                                     
REMARK 620 2 FES 3 787   S1  116.8                                              
REMARK 620 3 FES 3 787   S2  114.7 105.3                                        
REMARK 620 4 CYS 3  48   SG   88.5 115.1 116.5                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 1 439  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 1 353   SG                                                     
REMARK 620 2 SF4 1 439   S2  114.1                                              
REMARK 620 3 SF4 1 439   S3  115.3 105.9                                        
REMARK 620 4 SF4 1 439   S4  112.8 105.1 102.4                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 1 439  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 1 359   SG                                                     
REMARK 620 2 SF4 1 439   S1  109.8                                              
REMARK 620 3 SF4 1 439   S3  125.0 104.1                                        
REMARK 620 4 SF4 1 439   S4  107.0 105.1 104.2                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 1 439  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 1 356   SG                                                     
REMARK 620 2 SF4 1 439   S1  110.2                                              
REMARK 620 3 SF4 1 439   S2  119.0 106.3                                        
REMARK 620 4 SF4 1 439   S4  111.1 104.3 104.9                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 1 439  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 1 400   SG                                                     
REMARK 620 2 SF4 1 439   S1  113.9                                              
REMARK 620 3 SF4 1 439   S2  112.8 105.5                                        
REMARK 620 4 SF4 1 439   S3  114.8 103.0 105.9                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             FES 2 182  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 2  83   SG                                                     
REMARK 620 2 FES 2 182   S1  112.1                                              
REMARK 620 3 FES 2 182   S2  109.3 104.7                                        
REMARK 620 4 CYS 2  88   SG   97.2 117.4 116.1                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             FES 2 182  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS 2 124   SG                                                     
REMARK 620 2 FES 2 182   S1  118.6                                              
REMARK 620 3 FES 2 182   S2  118.3 103.8                                        
REMARK 620 4 CYS 2 128   SG   90.2 112.7 113.3                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 F 182  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS F 140   SG                                                     
REMARK 620 2 SF4 F 182   S2  113.7                                              
REMARK 620 3 SF4 F 182   S3  115.8 105.1                                        
REMARK 620 4 SF4 F 182   S4  112.7 103.4 104.9                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 F 182  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS F  46   SG                                                     
REMARK 620 2 SF4 F 182   S1  115.7                                              
REMARK 620 3 SF4 F 182   S3  109.8 105.4                                        
REMARK 620 4 SF4 F 182   S4  117.1 103.0 104.7                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 F 182  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS F 111   SG                                                     
REMARK 620 2 SF4 F 182   S1  115.6                                              
REMARK 620 3 SF4 F 182   S2  114.1 104.4                                        
REMARK 620 4 SF4 F 182   S4  111.8 105.4 104.5                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 F 182  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS F  45   SG                                                     
REMARK 620 2 SF4 F 182   S1  111.8                                              
REMARK 620 3 SF4 F 182   S2  119.5 103.9                                        
REMARK 620 4 SF4 F 182   S3  111.0 105.0 104.4                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 G 183  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS G  63   SG                                                     
REMARK 620 2 SF4 G 183   S2  113.3                                              
REMARK 620 3 SF4 G 183   S3  116.1 105.6                                        
REMARK 620 4 SF4 G 183   S4  110.2 105.0 105.9                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 G 183  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS G  98   SG                                                     
REMARK 620 2 SF4 G 183   S1  114.1                                              
REMARK 620 3 SF4 G 183   S3  116.0 105.2                                        
REMARK 620 4 SF4 G 183   S4  111.5 105.2 103.7                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 G 183  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS G 101   SG                                                     
REMARK 620 2 SF4 G 183   S1  119.1                                              
REMARK 620 3 SF4 G 183   S2  109.6 105.4                                        
REMARK 620 4 SF4 G 183   S4  112.7 105.1 103.7                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 G 183  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS G 104   SG                                                     
REMARK 620 2 SF4 G 183   S1  113.6                                              
REMARK 620 3 SF4 G 183   S2  113.0 105.9                                        
REMARK 620 4 SF4 G 183   S3  113.4 105.8 104.3                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 G 184  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS G  56   SG                                                     
REMARK 620 2 SF4 G 184   S2  116.4                                              
REMARK 620 3 SF4 G 184   S3  119.1 105.4                                        
REMARK 620 4 SF4 G 184   S4  105.2 104.2 105.0                                  
REMARK 620 5 CYS G  56   O    58.2 155.7  65.3 100.0                            
REMARK 620 N                    1     2     3     4                             
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 G 184  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS G  59   SG                                                     
REMARK 620 2 SF4 G 184   S1  117.9                                              
REMARK 620 3 SF4 G 184   S3  114.9 105.6                                        
REMARK 620 4 SF4 G 184   S4  107.1 104.4 105.8                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 G 184  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS G 108   SG                                                     
REMARK 620 2 SF4 G 184   S1  116.9                                              
REMARK 620 3 SF4 G 184   S2  112.1 106.1                                        
REMARK 620 4 SF4 G 184   S4  111.0 105.0 104.8                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 G 184  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS G  53   SG                                                     
REMARK 620 2 SF4 G 184   S1  114.0                                              
REMARK 620 3 SF4 G 184   S2  110.7 105.3                                        
REMARK 620 4 SF4 G 184   S3  115.3 105.0 105.8                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 C 784  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS C 122   SG                                                     
REMARK 620 2 SF4 C 784   S2  118.3                                              
REMARK 620 3 SF4 C 784   S3  113.4 105.1                                        
REMARK 620 4 SF4 C 784   S4  110.5 104.5 103.8                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 C 784  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS C 119   SG                                                     
REMARK 620 2 SF4 C 784   S1  112.9                                              
REMARK 620 3 SF4 C 784   S3  112.3 104.3                                        
REMARK 620 4 SF4 C 784   S4  117.3 104.5 104.2                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 C 784  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS C 128   SG                                                     
REMARK 620 2 SF4 C 784   S1  117.0                                              
REMARK 620 3 SF4 C 784   S2  111.2 106.1                                        
REMARK 620 4 SF4 C 784   S4  112.8 104.7 103.9                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 C 784  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 HIS C 115   NE2                                                    
REMARK 620 2 SF4 C 784   S1  110.5                                              
REMARK 620 3 SF4 C 784   S2  113.8 104.7                                        
REMARK 620 4 SF4 C 784   S3  118.5 105.0 103.2                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 C 785  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS C 230   SG                                                     
REMARK 620 2 SF4 C 785   S2  114.0                                              
REMARK 620 3 SF4 C 785   S3  115.1 105.6                                        
REMARK 620 4 SF4 C 785   S4  111.5 105.2 104.6                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 C 785  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS C 181   SG                                                     
REMARK 620 2 SF4 C 785   S1  121.6                                              
REMARK 620 3 SF4 C 785   S3  113.5 104.9                                        
REMARK 620 4 SF4 C 785   S4  105.5 104.9 105.0                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 C 785  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS C 184   SG                                                     
REMARK 620 2 SF4 C 785   S1  116.6                                              
REMARK 620 3 SF4 C 785   S2  103.2 106.4                                        
REMARK 620 4 SF4 C 785   S4  121.2 103.1 105.1                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 C 785  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS C 187   SG                                                     
REMARK 620 2 SF4 C 785   S1  112.9                                              
REMARK 620 3 SF4 C 785   S2  108.2 107.1                                        
REMARK 620 4 SF4 C 785   S3  119.5 103.1 105.3                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 C 786  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS C 259   SG                                                     
REMARK 620 2 SF4 C 786   S2  107.8                                              
REMARK 620 3 SF4 C 786   S3  114.4 106.3                                        
REMARK 620 4 SF4 C 786   S4  117.8 106.0 103.8                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 C 786  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS C 291   SG                                                     
REMARK 620 2 SF4 C 786   S1  112.7                                              
REMARK 620 3 SF4 C 786   S3  117.5 105.4                                        
REMARK 620 4 SF4 C 786   S4  110.9 105.9 103.5                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 C 786  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS C 256   SG                                                     
REMARK 620 2 SF4 C 786   S1  115.4                                              
REMARK 620 3 SF4 C 786   S2  112.6 105.8                                        
REMARK 620 4 SF4 C 786   S4  113.6 104.9 103.5                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 C 786  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS C 263   SG                                                     
REMARK 620 2 SF4 C 786   S1  114.5                                              
REMARK 620 3 SF4 C 786   S2  109.9 107.8                                        
REMARK 620 4 SF4 C 786   S3  115.8 103.5 104.5                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             FES C 787  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS C  45   SG                                                     
REMARK 620 2 FES C 787   S1  114.9                                              
REMARK 620 3 FES C 787   S2  113.0 102.3                                        
REMARK 620 4 CYS C  34   SG  109.0 113.6 103.3                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             FES C 787  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS C  83   SG                                                     
REMARK 620 2 FES C 787   S1  118.6                                              
REMARK 620 3 FES C 787   S2  113.6 102.8                                        
REMARK 620 4 CYS C  48   SG   92.3 116.4 113.7                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 A 439  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS A 353   SG                                                     
REMARK 620 2 SF4 A 439   S2  112.1                                              
REMARK 620 3 SF4 A 439   S3  113.5 107.3                                        
REMARK 620 4 SF4 A 439   S4  116.7 105.4 100.8                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 A 439  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS A 359   SG                                                     
REMARK 620 2 SF4 A 439   S1  107.1                                              
REMARK 620 3 SF4 A 439   S3  124.9 105.8                                        
REMARK 620 4 SF4 A 439   S4  109.2 104.1 103.8                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 A 439  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS A 356   SG                                                     
REMARK 620 2 SF4 A 439   S1  113.1                                              
REMARK 620 3 SF4 A 439   S2  117.0 106.7                                        
REMARK 620 4 SF4 A 439   S4  111.6 103.1 104.1                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 A 439  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS A 400   SG                                                     
REMARK 620 2 SF4 A 439   S1  114.6                                              
REMARK 620 3 SF4 A 439   S2  111.7 106.5                                        
REMARK 620 4 SF4 A 439   S3  115.7 101.9 105.5                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             FES B 182  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS B  83   SG                                                     
REMARK 620 2 FES B 182   S1  107.9                                              
REMARK 620 3 FES B 182   S2  110.1 103.0                                        
REMARK 620 4 CYS B  88   SG   99.2 119.5 116.7                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             FES B 182  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS B 124   SG                                                     
REMARK 620 2 FES B 182   S1  117.2                                              
REMARK 620 3 FES B 182   S2  119.3 102.5                                        
REMARK 620 4 CYS B 128   SG   93.7 112.4 112.1                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 O 182  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS O 140   SG                                                     
REMARK 620 2 SF4 O 182   S2  114.3                                              
REMARK 620 3 SF4 O 182   S3  117.6 105.5                                        
REMARK 620 4 SF4 O 182   S4  109.6 103.0 105.5                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 O 182  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS O  46   SG                                                     
REMARK 620 2 SF4 O 182   S1  116.4                                              
REMARK 620 3 SF4 O 182   S3  110.8 105.1                                        
REMARK 620 4 SF4 O 182   S4  115.6 102.9 104.8                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 O 182  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS O 111   SG                                                     
REMARK 620 2 SF4 O 182   S1  116.4                                              
REMARK 620 3 SF4 O 182   S2  113.6 105.0                                        
REMARK 620 4 SF4 O 182   S4  110.4 104.9 105.6                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 O 182  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS O  45   SG                                                     
REMARK 620 2 SF4 O 182   S1  111.7                                              
REMARK 620 3 SF4 O 182   S2  120.2 103.5                                        
REMARK 620 4 SF4 O 182   S3  109.9 105.5 105.0                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 P 183  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS P  63   SG                                                     
REMARK 620 2 SF4 P 183   S2  112.5                                              
REMARK 620 3 SF4 P 183   S3  119.0 103.7                                        
REMARK 620 4 SF4 P 183   S4  110.6 104.9 104.9                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 P 183  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS P  98   SG                                                     
REMARK 620 2 SF4 P 183   S1  113.5                                              
REMARK 620 3 SF4 P 183   S3  118.5 104.0                                        
REMARK 620 4 SF4 P 183   S4  111.0 106.1 102.7                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 P 183  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS P 101   SG                                                     
REMARK 620 2 SF4 P 183   S1  121.6                                              
REMARK 620 3 SF4 P 183   S2  109.8 104.4                                        
REMARK 620 4 SF4 P 183   S4  111.2 104.7 103.4                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 P 183  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS P 104   SG                                                     
REMARK 620 2 SF4 P 183   S1  114.3                                              
REMARK 620 3 SF4 P 183   S2  112.2 106.4                                        
REMARK 620 4 SF4 P 183   S3  114.6 105.0 103.4                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 P 184  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS P  56   SG                                                     
REMARK 620 2 SF4 P 184   S2  116.5                                              
REMARK 620 3 SF4 P 184   S3  118.3 104.4                                        
REMARK 620 4 SF4 P 184   S4  107.4 103.9 104.8                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 P 184  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS P  59   SG                                                     
REMARK 620 2 SF4 P 184   S1  116.2                                              
REMARK 620 3 SF4 P 184   S3  117.5 104.5                                        
REMARK 620 4 SF4 P 184   S4  108.2 104.2 105.0                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 P 184  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS P 108   SG                                                     
REMARK 620 2 SF4 P 184   S1  120.1                                              
REMARK 620 3 SF4 P 184   S2  112.9 104.9                                        
REMARK 620 4 SF4 P 184   S4  109.0 104.1 104.4                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 P 184  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS P  53   SG                                                     
REMARK 620 2 SF4 P 184   S1  114.5                                              
REMARK 620 3 SF4 P 184   S2  110.2 104.6                                        
REMARK 620 4 SF4 P 184   S3  116.1 104.9 105.5                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 L 784  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS L 122   SG                                                     
REMARK 620 2 SF4 L 784   S2  118.0                                              
REMARK 620 3 SF4 L 784   S3  113.0 106.2                                        
REMARK 620 4 SF4 L 784   S4  109.9 104.2 104.4                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 L 784  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS L 119   SG                                                     
REMARK 620 2 SF4 L 784   S1  111.9                                              
REMARK 620 3 SF4 L 784   S3  112.7 104.5                                        
REMARK 620 4 SF4 L 784   S4  117.5 104.4 104.5                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 L 784  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS L 128   SG                                                     
REMARK 620 2 SF4 L 784   S1  113.9                                              
REMARK 620 3 SF4 L 784   S2  114.4 105.2                                        
REMARK 620 4 SF4 L 784   S4  114.1 103.4 104.7                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 L 784  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 HIS L 115   NE2                                                    
REMARK 620 2 SF4 L 784   S1  107.7                                              
REMARK 620 3 SF4 L 784   S2  114.2 105.1                                        
REMARK 620 4 SF4 L 784   S3  119.6 104.6 104.5                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 L 785  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS L 230   SG                                                     
REMARK 620 2 SF4 L 785   S2  112.8                                              
REMARK 620 3 SF4 L 785   S3  117.2 104.7                                        
REMARK 620 4 SF4 L 785   S4  112.1 104.5 104.3                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 L 785  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS L 181   SG                                                     
REMARK 620 2 SF4 L 785   S1  122.9                                              
REMARK 620 3 SF4 L 785   S3  111.8 105.1                                        
REMARK 620 4 SF4 L 785   S4  106.5 104.4 104.5                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 L 785  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS L 184   SG                                                     
REMARK 620 2 SF4 L 785   S1  120.3                                              
REMARK 620 3 SF4 L 785   S2  103.3 105.6                                        
REMARK 620 4 SF4 L 785   S4  119.1 102.7 104.1                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 L 785  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS L 187   SG                                                     
REMARK 620 2 SF4 L 785   S1  115.4                                              
REMARK 620 3 SF4 L 785   S2  107.6 106.3                                        
REMARK 620 4 SF4 L 785   S3  119.0 102.3 105.3                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 L 786  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS L 259   SG                                                     
REMARK 620 2 SF4 L 786   S2  110.6                                              
REMARK 620 3 SF4 L 786   S3  113.0 105.6                                        
REMARK 620 4 SF4 L 786   S4  117.3 105.1 104.2                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 L 786  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS L 291   SG                                                     
REMARK 620 2 SF4 L 786   S1  113.3                                              
REMARK 620 3 SF4 L 786   S3  117.1 104.8                                        
REMARK 620 4 SF4 L 786   S4  110.2 106.2 104.3                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 L 786  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS L 256   SG                                                     
REMARK 620 2 SF4 L 786   S1  114.0                                              
REMARK 620 3 SF4 L 786   S2  112.4 105.6                                        
REMARK 620 4 SF4 L 786   S4  114.8 104.7 104.3                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 L 786  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS L 263   SG                                                     
REMARK 620 2 SF4 L 786   S1  117.4                                              
REMARK 620 3 SF4 L 786   S2  106.9 107.0                                        
REMARK 620 4 SF4 L 786   S3  115.5 104.2 104.9                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             FES L 787  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS L  45   SG                                                     
REMARK 620 2 FES L 787   S1  115.9                                              
REMARK 620 3 FES L 787   S2  113.3 102.8                                        
REMARK 620 4 CYS L  34   SG  105.2 114.2 105.1                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             FES L 787  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS L  83   SG                                                     
REMARK 620 2 FES L 787   S1  117.9                                              
REMARK 620 3 FES L 787   S2  113.6 105.6                                        
REMARK 620 4 CYS L  48   SG   91.6 115.4 112.8                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 J 439  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS J 353   SG                                                     
REMARK 620 2 SF4 J 439   S2  114.0                                              
REMARK 620 3 SF4 J 439   S3  113.6 106.0                                        
REMARK 620 4 SF4 J 439   S4  115.1 105.1 102.0                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 J 439  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS J 359   SG                                                     
REMARK 620 2 SF4 J 439   S1  107.2                                              
REMARK 620 3 SF4 J 439   S3  125.1 105.0                                        
REMARK 620 4 SF4 J 439   S4  110.0 105.2 102.6                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 J 439  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS J 356   SG                                                     
REMARK 620 2 SF4 J 439   S1  112.2                                              
REMARK 620 3 SF4 J 439   S2  118.6 106.5                                        
REMARK 620 4 SF4 J 439   S4  111.6 103.4 103.1                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 J 439  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS J 400   SG                                                     
REMARK 620 2 SF4 J 439   S1  113.1                                              
REMARK 620 3 SF4 J 439   S2  113.2 106.9                                        
REMARK 620 4 SF4 J 439   S3  115.9 102.5 104.3                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             FES K 182  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS K  83   SG                                                     
REMARK 620 2 FES K 182   S1  112.8                                              
REMARK 620 3 FES K 182   S2  111.1 106.1                                        
REMARK 620 4 CYS K  88   SG   94.0 118.4 114.2                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             FES K 182  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS K 124   SG                                                     
REMARK 620 2 FES K 182   S1  114.8                                              
REMARK 620 3 FES K 182   S2  118.3 107.4                                        
REMARK 620 4 CYS K 128   SG   89.9 114.0 111.8                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 X 182  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS X 140   SG                                                     
REMARK 620 2 SF4 X 182   S2  113.2                                              
REMARK 620 3 SF4 X 182   S3  115.8 106.2                                        
REMARK 620 4 SF4 X 182   S4  111.6 103.4 105.6                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 X 182  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS X  46   SG                                                     
REMARK 620 2 SF4 X 182   S1  115.1                                              
REMARK 620 3 SF4 X 182   S3  112.3 106.3                                        
REMARK 620 4 SF4 X 182   S4  114.7 103.9 103.3                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 X 182  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS X 111   SG                                                     
REMARK 620 2 SF4 X 182   S1  109.8                                              
REMARK 620 3 SF4 X 182   S2  113.3 106.0                                        
REMARK 620 4 SF4 X 182   S4  117.2 106.7 103.1                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 X 182  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS X  45   SG                                                     
REMARK 620 2 SF4 X 182   S1  112.9                                              
REMARK 620 3 SF4 X 182   S2  118.8 104.9                                        
REMARK 620 4 SF4 X 182   S3  111.5 105.9 101.5                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 Y 183  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS Y  63   SG                                                     
REMARK 620 2 SF4 Y 183   S2  113.5                                              
REMARK 620 3 SF4 Y 183   S3  120.0 102.9                                        
REMARK 620 4 SF4 Y 183   S4  108.8 105.3 105.2                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 Y 183  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS Y  98   SG                                                     
REMARK 620 2 SF4 Y 183   S1  115.1                                              
REMARK 620 3 SF4 Y 183   S3  115.3 103.1                                        
REMARK 620 4 SF4 Y 183   S4  113.3 105.3 103.4                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 Y 183  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS Y 101   SG                                                     
REMARK 620 2 SF4 Y 183   S1  121.1                                              
REMARK 620 3 SF4 Y 183   S2  111.2 103.3                                        
REMARK 620 4 SF4 Y 183   S4  111.4 103.9 104.3                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 Y 183  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS Y 104   SG                                                     
REMARK 620 2 SF4 Y 183   S1  112.3                                              
REMARK 620 3 SF4 Y 183   S2  113.8 105.3                                        
REMARK 620 4 SF4 Y 183   S3  115.7 104.2 104.5                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 Y 184  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS Y  56   SG                                                     
REMARK 620 2 SF4 Y 184   S2  114.6                                              
REMARK 620 3 SF4 Y 184   S3  119.7 105.1                                        
REMARK 620 4 SF4 Y 184   S4  106.8 104.7 104.5                                  
REMARK 620 5 CYS Y  56   O    60.1 154.1  64.2 100.9                            
REMARK 620 N                    1     2     3     4                             
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 Y 184  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS Y  59   SG                                                     
REMARK 620 2 SF4 Y 184   S1  118.0                                              
REMARK 620 3 SF4 Y 184   S3  114.6 105.3                                        
REMARK 620 4 SF4 Y 184   S4  107.2 105.1 105.5                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 Y 184  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS Y 108   SG                                                     
REMARK 620 2 SF4 Y 184   S1  117.6                                              
REMARK 620 3 SF4 Y 184   S2  111.0 105.8                                        
REMARK 620 4 SF4 Y 184   S4  112.1 104.5 104.8                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 Y 184  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS Y  53   SG                                                     
REMARK 620 2 SF4 Y 184   S1  114.1                                              
REMARK 620 3 SF4 Y 184   S2  110.4 105.9                                        
REMARK 620 4 SF4 Y 184   S3  115.3 104.8 105.5                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 U 784  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS U 122   SG                                                     
REMARK 620 2 SF4 U 784   S2  118.5                                              
REMARK 620 3 SF4 U 784   S3  112.0 105.7                                        
REMARK 620 4 SF4 U 784   S4  110.5 103.7 105.3                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 U 784  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS U 119   SG                                                     
REMARK 620 2 SF4 U 784   S1  114.1                                              
REMARK 620 3 SF4 U 784   S3  110.6 104.7                                        
REMARK 620 4 SF4 U 784   S4  117.3 103.6 105.4                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 U 784  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS U 128   SG                                                     
REMARK 620 2 SF4 U 784   S1  115.8                                              
REMARK 620 3 SF4 U 784   S2  111.3 104.8                                        
REMARK 620 4 SF4 U 784   S4  113.6 105.2 105.2                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 U 784  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 HIS U 115   NE2                                                    
REMARK 620 2 SF4 U 784   S1  110.4                                              
REMARK 620 3 SF4 U 784   S2  116.9 104.5                                        
REMARK 620 4 SF4 U 784   S3  114.4 105.2 104.3                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 U 785  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS U 230   SG                                                     
REMARK 620 2 SF4 U 785   S2  111.4                                              
REMARK 620 3 SF4 U 785   S3  116.8 105.8                                        
REMARK 620 4 SF4 U 785   S4  113.1 103.5 105.0                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 U 785  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS U 181   SG                                                     
REMARK 620 2 SF4 U 785   S1  123.7                                              
REMARK 620 3 SF4 U 785   S3  113.9 105.5                                        
REMARK 620 4 SF4 U 785   S4  104.6 103.2 103.5                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 U 785  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS U 184   SG                                                     
REMARK 620 2 SF4 U 785   S1  117.7                                              
REMARK 620 3 SF4 U 785   S2  103.7 106.2                                        
REMARK 620 4 SF4 U 785   S4  121.2 103.1 103.3                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 U 785  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS U 187   SG                                                     
REMARK 620 2 SF4 U 785   S1  113.0                                              
REMARK 620 3 SF4 U 785   S2  108.6 106.0                                        
REMARK 620 4 SF4 U 785   S3  119.7 103.9 104.5                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 U 786  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS U 259   SG                                                     
REMARK 620 2 SF4 U 786   S2  112.5                                              
REMARK 620 3 SF4 U 786   S3  110.9 105.5                                        
REMARK 620 4 SF4 U 786   S4  118.1 105.5 103.2                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 U 786  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS U 291   SG                                                     
REMARK 620 2 SF4 U 786   S1  113.4                                              
REMARK 620 3 SF4 U 786   S3  116.2 103.5                                        
REMARK 620 4 SF4 U 786   S4  112.3 105.9 104.6                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 U 786  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS U 256   SG                                                     
REMARK 620 2 SF4 U 786   S1  112.8                                              
REMARK 620 3 SF4 U 786   S2  112.9 104.6                                        
REMARK 620 4 SF4 U 786   S4  117.4 103.7 104.2                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 U 786  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS U 263   SG                                                     
REMARK 620 2 SF4 U 786   S1  116.1                                              
REMARK 620 3 SF4 U 786   S2  111.1 106.5                                        
REMARK 620 4 SF4 U 786   S3  115.7 102.5 103.8                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             FES U 787  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS U  45   SG                                                     
REMARK 620 2 FES U 787   S1  114.8                                              
REMARK 620 3 FES U 787   S2  113.8 103.2                                        
REMARK 620 4 CYS U  34   SG  108.9 110.9 104.7                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             FES U 787  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS U  83   SG                                                     
REMARK 620 2 FES U 787   S1  115.1                                              
REMARK 620 3 FES U 787   S2  116.6 103.2                                        
REMARK 620 4 CYS U  48   SG   90.3 116.6 115.6                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 S 439  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS S 353   SG                                                     
REMARK 620 2 SF4 S 439   S2  116.2                                              
REMARK 620 3 SF4 S 439   S3  112.5 107.0                                        
REMARK 620 4 SF4 S 439   S4  112.3 105.1 102.6                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 S 439  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS S 359   SG                                                     
REMARK 620 2 SF4 S 439   S1  106.8                                              
REMARK 620 3 SF4 S 439   S3  126.5 104.5                                        
REMARK 620 4 SF4 S 439   S4  107.9 103.7 105.3                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 S 439  FE3                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS S 356   SG                                                     
REMARK 620 2 SF4 S 439   S1  107.8                                              
REMARK 620 3 SF4 S 439   S2  119.0 106.1                                        
REMARK 620 4 SF4 S 439   S4  112.9 103.3 106.4                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             SF4 S 439  FE4                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS S 400   SG                                                     
REMARK 620 2 SF4 S 439   S1  111.5                                              
REMARK 620 3 SF4 S 439   S2  114.9 106.0                                        
REMARK 620 4 SF4 S 439   S3  115.2 100.5 107.3                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             FES T 182  FE1                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS T  83   SG                                                     
REMARK 620 2 FES T 182   S1  114.9                                              
REMARK 620 3 FES T 182   S2  110.0 101.2                                        
REMARK 620 4 CYS T  88   SG   94.0 117.2 120.1                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                             FES T 182  FE2                           
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS T 124   SG                                                     
REMARK 620 2 FES T 182   S1  112.7                                              
REMARK 620 3 FES T 182   S2  114.6 101.0                                        
REMARK 620 4 CYS T 128   SG   95.0 113.9 120.3                                  
REMARK 620 N                    1     2     3                                   
REMARK 800                                                                      
REMARK 800 SITE                                                                 
REMARK 800 SITE_IDENTIFIER: AC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 6 182                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 9 183                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC3                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 9 184                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC4                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 3 784                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC5                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 3 785                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC6                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 3 786                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC7                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE FES 3 787                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC8                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 1 439                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC9                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE FES 2 182                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: BC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE FMN 7 500                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: BC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 F 182                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: BC3                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 G 183                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: BC4                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 G 184                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: BC5                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 C 784                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: BC6                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 C 785                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: BC7                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 C 786                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: BC8                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE FES C 787                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: BC9                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 A 439                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: CC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE FES B 182                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: CC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE FMN H 500                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: CC3                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 O 182                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: CC4                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 P 183                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: CC5                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 P 184                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: CC6                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 L 784                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: CC7                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 L 785                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: CC8                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 L 786                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: CC9                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE FES L 787                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: DC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 J 439                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: DC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE FES K 182                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: DC3                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE FMN Q 500                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: DC4                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 X 182                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: DC5                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 Y 183                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: DC6                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 Y 184                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: DC7                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 U 784                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: DC8                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 U 785                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: DC9                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 U 786                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: EC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE FES U 787                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: EC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SF4 S 439                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: EC3                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE FES T 182                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: EC4                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE FMN Z 500                 
DBREF  2FUG 1    1   438  UNP    Q56222   NQO1_THET8       1    438             
DBREF  2FUG A    1   438  UNP    Q56222   NQO1_THET8       1    438             
DBREF  2FUG J    1   438  UNP    Q56222   NQO1_THET8       1    438             
DBREF  2FUG S    1   438  UNP    Q56222   NQO1_THET8       1    438             
DBREF  2FUG 2    1   181  UNP    Q56221   NQO2_THET8       1    181             
DBREF  2FUG B    1   181  UNP    Q56221   NQO2_THET8       1    181             
DBREF  2FUG K    1   181  UNP    Q56221   NQO2_THET8       1    181             
DBREF  2FUG T    1   181  UNP    Q56221   NQO2_THET8       1    181             
DBREF  2FUG 3    1   783  UNP    Q56223   NQO3_THET8       1    783             
DBREF  2FUG C    1   783  UNP    Q56223   NQO3_THET8       1    783             
DBREF  2FUG L    1   783  UNP    Q56223   NQO3_THET8       1    783             
DBREF  2FUG U    1   783  UNP    Q56223   NQO3_THET8       1    783             
DBREF  2FUG 4    1   409  UNP    Q56220   NQO4_THET8       1    409             
DBREF  2FUG D    1   409  UNP    Q56220   NQO4_THET8       1    409             
DBREF  2FUG M    1   409  UNP    Q56220   NQO4_THET8       1    409             
DBREF  2FUG V    1   409  UNP    Q56220   NQO4_THET8       1    409             
DBREF  2FUG 5    1   207  UNP    Q56219   NQO5_THET8       1    207             
DBREF  2FUG E    1   207  UNP    Q56219   NQO5_THET8       1    207             
DBREF  2FUG N    1   207  UNP    Q56219   NQO5_THET8       1    207             
DBREF  2FUG W    1   207  UNP    Q56219   NQO5_THET8       1    207             
DBREF  2FUG 6    1   181  UNP    Q56218   NQO6_THET8       1    181             
DBREF  2FUG F    1   181  UNP    Q56218   NQO6_THET8       1    181             
DBREF  2FUG O    1   181  UNP    Q56218   NQO6_THET8       1    181             
DBREF  2FUG X    1   181  UNP    Q56218   NQO6_THET8       1    181             
DBREF  2FUG 9    1   182  UNP    Q56224   NQO9_THET8       1    182             
DBREF  2FUG G    1   182  UNP    Q56224   NQO9_THET8       1    182             
DBREF  2FUG P    1   182  UNP    Q56224   NQO9_THET8       1    182             
DBREF  2FUG Y    1   182  UNP    Q56224   NQO9_THET8       1    182             
DBREF  2FUG 7    1   129  GB     55771878 BAD70319         1    129             
DBREF  2FUG H    1   129  GB     55771878 BAD70319         1    129             
DBREF  2FUG Q    1   129  GB     55771878 BAD70319         1    129             
DBREF  2FUG Z    1   129  GB     55771878 BAD70319         1    129             
SEQRES   1 1  438  MET THR GLY PRO ILE LEU SER GLY LEU ASP PRO ARG PHE          
SEQRES   2 1  438  GLU ARG THR LEU TYR ALA HIS VAL GLY LYS GLU GLY SER          
SEQRES   3 1  438  TRP THR LEU ASP TYR TYR LEU ARG HIS GLY GLY TYR GLU          
SEQRES   4 1  438  THR ALA LYS ARG VAL LEU LYS GLU LYS THR PRO ASP GLU          
SEQRES   5 1  438  VAL ILE GLU GLU VAL LYS ARG SER GLY LEU ARG GLY ARG          
SEQRES   6 1  438  GLY GLY ALA GLY PHE PRO THR GLY LEU LYS TRP SER PHE          
SEQRES   7 1  438  MET PRO LYS ASP ASP GLY LYS GLN HIS TYR LEU ILE CYS          
SEQRES   8 1  438  ASN ALA ASP GLU SER GLU PRO GLY SER PHE LYS ASP ARG          
SEQRES   9 1  438  TYR ILE LEU GLU ASP VAL PRO HIS LEU LEU ILE GLU GLY          
SEQRES  10 1  438  MET ILE LEU ALA GLY TYR ALA ILE ARG ALA THR VAL GLY          
SEQRES  11 1  438  TYR ILE TYR VAL ARG GLY GLU TYR ARG ARG ALA ALA ASP          
SEQRES  12 1  438  ARG LEU GLU GLN ALA ILE LYS GLU ALA ARG ALA ARG GLY          
SEQRES  13 1  438  TYR LEU GLY LYS ASN LEU PHE GLY THR ASP PHE SER PHE          
SEQRES  14 1  438  ASP LEU HIS VAL HIS ARG GLY ALA GLY ALA TYR ILE CYS          
SEQRES  15 1  438  GLY GLU GLU THR ALA LEU MET ASN SER LEU GLU GLY LEU          
SEQRES  16 1  438  ARG ALA ASN PRO ARG LEU LYS PRO PRO PHE PRO ALA GLN          
SEQRES  17 1  438  SER GLY LEU TRP GLY LYS PRO THR THR ILE ASN ASN VAL          
SEQRES  18 1  438  GLU THR LEU ALA SER VAL VAL PRO ILE MET GLU ARG GLY          
SEQRES  19 1  438  ALA ASP TRP PHE ALA GLN MET GLY THR GLU GLN SER LYS          
SEQRES  20 1  438  GLY MET LYS LEU TYR GLN ILE SER GLY PRO VAL LYS ARG          
SEQRES  21 1  438  PRO GLY VAL TYR GLU LEU PRO MET GLY THR THR PHE ARG          
SEQRES  22 1  438  GLU LEU ILE TYR GLU TRP ALA GLY GLY PRO LEU GLU PRO          
SEQRES  23 1  438  ILE GLN ALA ILE ILE PRO GLY GLY SER SER THR PRO PRO          
SEQRES  24 1  438  LEU PRO PHE THR GLU GLU VAL LEU ASP THR PRO MET SER          
SEQRES  25 1  438  TYR GLU HIS LEU GLN ALA LYS GLY SER MET LEU GLY THR          
SEQRES  26 1  438  GLY GLY VAL ILE LEU ILE PRO GLU ARG VAL SER MET VAL          
SEQRES  27 1  438  ASP ALA MET TRP ASN LEU THR ARG PHE TYR ALA HIS GLU          
SEQRES  28 1  438  SER CYS GLY LYS CYS THR PRO CYS ARG GLU GLY VAL ALA          
SEQRES  29 1  438  GLY PHE MET VAL ASN LEU PHE ALA LYS ILE GLY THR GLY          
SEQRES  30 1  438  GLN GLY GLU GLU LYS ASP VAL GLU ASN LEU GLU ALA LEU          
SEQRES  31 1  438  LEU PRO LEU ILE GLU GLY ARG SER PHE CYS PRO LEU ALA          
SEQRES  32 1  438  ASP ALA ALA VAL TRP PRO VAL LYS GLY SER LEU ARG HIS          
SEQRES  33 1  438  PHE LYS ASP GLN TYR LEU ALA LEU ALA ARG GLU LYS ARG          
SEQRES  34 1  438  PRO VAL PRO ARG PRO SER LEU TRP ARG                          
SEQRES   1 2  181  MET GLY PHE PHE ASP ASP LYS GLN ASP PHE LEU GLU GLU          
SEQRES   2 2  181  THR PHE ALA LYS TYR PRO PRO GLU GLY ARG ARG ALA ALA          
SEQRES   3 2  181  ILE MET PRO LEU LEU ARG ARG VAL GLN GLN GLU GLU GLY          
SEQRES   4 2  181  TRP ILE ARG PRO GLU ARG ILE GLU GLU ILE ALA ARG LEU          
SEQRES   5 2  181  VAL GLY THR THR PRO THR GLU VAL MET GLY VAL ALA SER          
SEQRES   6 2  181  PHE TYR SER TYR TYR GLN PHE VAL PRO THR GLY LYS TYR          
SEQRES   7 2  181  HIS LEU GLN VAL CYS ALA THR LEU SER CYS LYS LEU ALA          
SEQRES   8 2  181  GLY ALA GLU GLU LEU TRP ASP TYR LEU THR GLU THR LEU          
SEQRES   9 2  181  GLY ILE GLY PRO GLY GLU VAL THR PRO ASP GLY LEU PHE          
SEQRES  10 2  181  SER VAL GLN LYS VAL GLU CYS LEU GLY SER CYS HIS THR          
SEQRES  11 2  181  ALA PRO VAL ILE GLN VAL ASN ASP GLU PRO TYR VAL GLU          
SEQRES  12 2  181  CYS VAL THR ARG ALA ARG LEU GLU ALA LEU LEU ALA GLY          
SEQRES  13 2  181  LEU ARG ALA GLY LYS ARG LEU GLU GLU ILE GLU LEU PRO          
SEQRES  14 2  181  GLY LYS CYS GLY HIS HIS VAL HIS GLU VAL GLU VAL              
SEQRES   1 3  783  MET VAL ARG VAL LYS VAL ASN ASP ARG ILE VAL GLU VAL          
SEQRES   2 3  783  PRO PRO GLY THR SER VAL MET ASP ALA VAL PHE HIS ALA          
SEQRES   3 3  783  GLY TYR ASP VAL PRO LEU PHE CYS SER GLU LYS HIS LEU          
SEQRES   4 3  783  SER PRO ILE GLY ALA CYS ARG MET CYS LEU VAL ARG ILE          
SEQRES   5 3  783  GLY LEU PRO LYS LYS GLY PRO ASP GLY LYS PRO LEU LEU          
SEQRES   6 3  783  ASN GLU LYS GLY GLU PRO GLU ILE GLN TRP GLN PRO LYS          
SEQRES   7 3  783  LEU ALA ALA SER CYS VAL THR ALA VAL ALA ASP GLY MET          
SEQRES   8 3  783  VAL VAL ASP THR LEU SER ASP VAL VAL ARG GLU ALA GLN          
SEQRES   9 3  783  ALA GLY MET VAL GLU PHE THR LEU LEU ASN HIS PRO LEU          
SEQRES  10 3  783  ASP CYS PRO THR CYS ASP LYS GLY GLY ALA CYS GLU LEU          
SEQRES  11 3  783  GLN ASP ARG THR VAL GLU TYR GLY LEU TYR GLU LYS TYR          
SEQRES  12 3  783  TYR GLN LYS GLY PRO LEU GLU LEU PRO VAL TYR THR ARG          
SEQRES  13 3  783  PHE GLU PHE THR ARG ARG HIS VAL ASP LYS HIS HIS PRO          
SEQRES  14 3  783  LEU SER PRO PHE VAL ILE LEU ASP ARG GLU ARG CYS ILE          
SEQRES  15 3  783  HIS CYS LYS ARG CYS VAL ARG TYR PHE GLU GLU VAL PRO          
SEQRES  16 3  783  GLY ASP GLU VAL LEU ASP PHE ILE GLU ARG GLY VAL HIS          
SEQRES  17 3  783  THR PHE ILE GLY THR MET ASP PHE GLY LEU PRO SER GLY          
SEQRES  18 3  783  PHE SER GLY ASN ILE THR ASP ILE CYS PRO VAL GLY ALA          
SEQRES  19 3  783  LEU LEU ASP LEU THR ALA ARG PHE ARG ALA ARG ASN TRP          
SEQRES  20 3  783  GLU MET GLU GLU THR PRO THR THR CYS ALA LEU CYS PRO          
SEQRES  21 3  783  VAL GLY CYS GLY ILE THR ALA ASP THR ARG SER GLY GLU          
SEQRES  22 3  783  LEU LEU ARG ILE ARG ALA ARG GLU VAL PRO GLU VAL ASN          
SEQRES  23 3  783  GLU ILE TRP ILE CYS ASP ALA GLY ARG PHE GLY HIS GLU          
SEQRES  24 3  783  TRP ALA ASP GLN ASN ARG LEU LYS THR PRO LEU VAL ARG          
SEQRES  25 3  783  LYS GLU GLY ARG LEU VAL GLU ALA THR TRP GLU GLU ALA          
SEQRES  26 3  783  PHE LEU ALA LEU LYS GLU GLY LEU LYS GLU ALA ARG GLY          
SEQRES  27 3  783  GLU GLU VAL GLY LEU TYR LEU ALA HIS ASP ALA THR LEU          
SEQRES  28 3  783  GLU GLU GLY LEU LEU ALA SER GLU LEU ALA LYS ALA LEU          
SEQRES  29 3  783  LYS THR PRO HIS LEU ASP PHE GLN GLY ARG THR ALA ALA          
SEQRES  30 3  783  PRO ALA SER LEU PHE PRO PRO ALA SER LEU GLU ASP LEU          
SEQRES  31 3  783  LEU GLN ALA ASP PHE ALA LEU VAL LEU GLY ASP PRO THR          
SEQRES  32 3  783  GLU GLU ALA PRO ILE LEU HIS LEU ARG LEU SER GLU PHE          
SEQRES  33 3  783  VAL ARG ASP LEU LYS PRO PRO HIS ARG TYR ASN HIS GLY          
SEQRES  34 3  783  THR PRO PHE ALA ASP LEU GLN ILE LYS GLU ARG MET PRO          
SEQRES  35 3  783  ARG ARG THR ASP LYS MET ALA LEU PHE ALA PRO TYR ARG          
SEQRES  36 3  783  ALA PRO LEU MET LYS TRP ALA ALA ILE HIS GLU VAL HIS          
SEQRES  37 3  783  ARG PRO GLY GLU GLU ARG GLU ILE LEU LEU ALA LEU LEU          
SEQRES  38 3  783  GLY ASP LYS GLU GLY SER GLU MET VAL ALA LYS ALA LYS          
SEQRES  39 3  783  GLU ALA TRP GLU LYS ALA LYS ASN PRO VAL LEU ILE LEU          
SEQRES  40 3  783  GLY ALA GLY VAL LEU GLN ASP THR VAL ALA ALA GLU ARG          
SEQRES  41 3  783  ALA ARG LEU LEU ALA GLU ARG LYS GLY ALA LYS VAL LEU          
SEQRES  42 3  783  ALA MET THR PRO ALA ALA ASN ALA ARG GLY LEU GLU ALA          
SEQRES  43 3  783  MET GLY VAL LEU PRO GLY ALA LYS GLY ALA SER TRP ASP          
SEQRES  44 3  783  GLU PRO GLY ALA LEU TYR ALA TYR TYR GLY PHE VAL PRO          
SEQRES  45 3  783  PRO GLU GLU ALA LEU LYS GLY LYS ARG PHE VAL VAL MET          
SEQRES  46 3  783  HIS LEU SER HIS LEU HIS PRO LEU ALA GLU ARG TYR ALA          
SEQRES  47 3  783  HIS VAL VAL LEU PRO ALA PRO THR PHE TYR GLU LYS ARG          
SEQRES  48 3  783  GLY HIS LEU VAL ASN LEU GLU GLY ARG VAL LEU PRO LEU          
SEQRES  49 3  783  SER PRO ALA PRO ILE GLU ASN GLY GLU ALA GLU GLY ALA          
SEQRES  50 3  783  LEU GLN VAL LEU ALA LEU LEU ALA GLU ALA LEU GLY VAL          
SEQRES  51 3  783  ARG PRO PRO PHE ARG LEU HIS LEU GLU ALA GLN LYS ALA          
SEQRES  52 3  783  LEU LYS ALA ARG LYS VAL PRO GLU ALA MET GLY ARG LEU          
SEQRES  53 3  783  SER PHE ARG LEU LYS GLU LEU ARG PRO LYS GLU ARG LYS          
SEQRES  54 3  783  GLY ALA PHE TYR LEU ARG PRO THR MET TRP LYS ALA HIS          
SEQRES  55 3  783  GLN ALA VAL GLY LYS ALA GLN GLU ALA ALA ARG ALA GLU          
SEQRES  56 3  783  LEU TRP ALA HIS PRO GLU THR ALA ARG ALA GLU ALA LEU          
SEQRES  57 3  783  PRO GLU GLY ALA GLN VAL ALA VAL GLU THR PRO PHE GLY          
SEQRES  58 3  783  ARG VAL GLU ALA ARG VAL VAL HIS ARG GLU ASP VAL PRO          
SEQRES  59 3  783  LYS GLY HIS LEU TYR LEU SER ALA LEU GLY PRO ALA ALA          
SEQRES  60 3  783  GLY LEU ARG VAL GLU GLY ARG VAL LEU VAL PRO ALA GLY          
SEQRES  61 3  783  GLY GLU ALA                                                  
SEQRES   1 4  409  MET ARG GLU GLU PHE LEU GLU GLU ILE PRO LEU ASP ALA          
SEQRES   2 4  409  PRO PRO GLU GLU ALA LYS GLU LEU ARG THR GLU VAL MET          
SEQRES   3 4  409  THR LEU ASN VAL GLY PRO GLN HIS PRO SER THR HIS GLY          
SEQRES   4 4  409  VAL LEU ARG LEU MET VAL THR LEU SER GLY GLU GLU VAL          
SEQRES   5 4  409  LEU GLU VAL VAL PRO HIS ILE GLY TYR LEU HIS THR GLY          
SEQRES   6 4  409  PHE GLU LYS THR MET GLU HIS ARG THR TYR LEU GLN ASN          
SEQRES   7 4  409  ILE THR TYR THR PRO ARG MET ASP TYR LEU HIS SER PHE          
SEQRES   8 4  409  ALA HIS ASP LEU ALA TYR ALA LEU ALA VAL GLU LYS LEU          
SEQRES   9 4  409  LEU GLY ALA VAL VAL PRO PRO ARG ALA GLU THR ILE ARG          
SEQRES  10 4  409  VAL ILE LEU ASN GLU LEU SER ARG LEU ALA SER HIS LEU          
SEQRES  11 4  409  VAL PHE LEU GLY THR GLY LEU LEU ASP LEU GLY ALA LEU          
SEQRES  12 4  409  THR PRO PHE PHE TYR ALA PHE ARG GLU ARG GLU THR ILE          
SEQRES  13 4  409  LEU ASP LEU PHE GLU TRP VAL THR GLY GLN ARG PHE HIS          
SEQRES  14 4  409  HIS ASN TYR ILE ARG ILE GLY GLY VAL LYS GLU ASP LEU          
SEQRES  15 4  409  PRO GLU GLU PHE VAL PRO GLU LEU LYS LYS LEU LEU GLU          
SEQRES  16 4  409  VAL LEU PRO HIS ARG ILE ASP GLU TYR GLU ALA LEU PHE          
SEQRES  17 4  409  ALA GLU SER PRO ILE PHE TYR GLU ARG ALA ARG GLY VAL          
SEQRES  18 4  409  GLY VAL ILE PRO PRO GLU VAL ALA ILE ASP LEU GLY LEU          
SEQRES  19 4  409  THR GLY GLY SER LEU ARG ALA SER GLY VAL ASN TYR ASP          
SEQRES  20 4  409  VAL ARG LYS ALA TYR PRO TYR SER GLY TYR GLU THR TYR          
SEQRES  21 4  409  THR PHE ASP VAL PRO LEU GLY GLU ARG GLY ASP VAL PHE          
SEQRES  22 4  409  ASP ARG MET LEU VAL ARG ILE ARG GLU MET ARG GLU SER          
SEQRES  23 4  409  VAL LYS ILE ILE LYS GLN ALA LEU GLU ARG LEU GLU PRO          
SEQRES  24 4  409  GLY PRO VAL ARG ASP PRO ASN PRO GLN ILE THR PRO PRO          
SEQRES  25 4  409  PRO ARG HIS LEU LEU GLU THR SER MET GLU ALA VAL ILE          
SEQRES  26 4  409  TYR HIS PHE LYS HIS TYR THR GLU GLY PHE HIS PRO PRO          
SEQRES  27 4  409  LYS GLY GLU VAL TYR VAL PRO THR GLU SER ALA ARG GLY          
SEQRES  28 4  409  GLU LEU GLY TYR TYR ILE VAL SER ASP GLY GLY SER MET          
SEQRES  29 4  409  PRO TYR ARG VAL LYS VAL ARG ALA PRO SER PHE VAL ASN          
SEQRES  30 4  409  LEU GLN SER LEU PRO TYR ALA CYS LYS GLY GLU GLN VAL          
SEQRES  31 4  409  PRO ASP MET VAL ALA ILE ILE ALA SER LEU ASP PRO VAL          
SEQRES  32 4  409  MET GLY ASP VAL ASP ARG                                      
SEQRES   1 5  207  MET ARG LEU GLU ARG VAL LEU GLU GLU ALA ARG ALA LYS          
SEQRES   2 5  207  GLY TYR PRO ILE GLU ASP ASN GLY LEU GLY ASN LEU TRP          
SEQRES   3 5  207  VAL VAL LEU PRO ARG GLU ARG PHE LYS GLU GLU MET ALA          
SEQRES   4 5  207  HIS TYR LYS ALA MET GLY PHE ASN PHE LEU ALA ASP ILE          
SEQRES   5 5  207  VAL GLY LEU ASP TYR LEU THR TYR PRO ASP PRO ARG PRO          
SEQRES   6 5  207  GLU ARG PHE ALA VAL VAL TYR GLU LEU VAL SER LEU PRO          
SEQRES   7 5  207  GLY TRP LYS ASP GLY ASP GLY SER ARG PHE PHE VAL ARG          
SEQRES   8 5  207  VAL TYR VAL PRO GLU GLU ASP PRO ARG LEU PRO THR VAL          
SEQRES   9 5  207  THR ASP LEU TRP GLY SER ALA ASN PHE LEU GLU ARG GLU          
SEQRES  10 5  207  VAL TYR ASP LEU PHE GLY ILE VAL PHE GLU GLY HIS PRO          
SEQRES  11 5  207  ASP LEU ARG LYS ILE LEU THR PRO GLU ASP LEU GLU GLY          
SEQRES  12 5  207  HIS PRO LEU ARG LYS ASP TYR PRO LEU GLY GLU THR PRO          
SEQRES  13 5  207  THR LEU PHE ARG GLU GLY ARG TYR ILE ILE PRO ALA GLU          
SEQRES  14 5  207  PHE ARG ALA ALA LEU THR GLY LYS ASP PRO GLY LEU THR          
SEQRES  15 5  207  PHE TYR LYS GLY GLY SER ARG LYS GLY TYR ARG SER LEU          
SEQRES  16 5  207  TRP ALA ASP LEU LYS LYS ALA ARG GLU VAL LYS GLY              
SEQRES   1 6  181  MET ALA LEU LYS ASP LEU PHE GLU ARG ASP VAL GLN GLU          
SEQRES   2 6  181  LEU GLU ARG GLU GLY ILE LEU PHE THR THR LEU GLU LYS          
SEQRES   3 6  181  LEU VAL ALA TRP GLY ARG SER ASN SER LEU TRP PRO ALA          
SEQRES   4 6  181  THR PHE GLY LEU ALA CYS CYS ALA ILE GLU MET MET ALA          
SEQRES   5 6  181  SER THR ASP ALA ARG ASN ASP LEU ALA ARG PHE GLY SER          
SEQRES   6 6  181  GLU VAL PHE ARG ALA SER PRO ARG GLN ALA ASP VAL MET          
SEQRES   7 6  181  ILE VAL ALA GLY ARG LEU SER LYS LYS MET ALA PRO VAL          
SEQRES   8 6  181  MET ARG ARG VAL TRP GLU GLN MET PRO ASP PRO LYS TRP          
SEQRES   9 6  181  VAL ILE SER MET GLY ALA CYS ALA SER SER GLY GLY MET          
SEQRES  10 6  181  PHE ASN ASN TYR ALA ILE VAL GLN ASN VAL ASP SER VAL          
SEQRES  11 6  181  VAL PRO VAL ASP VAL TYR VAL PRO GLY CYS PRO PRO ARG          
SEQRES  12 6  181  PRO GLU ALA LEU ILE TYR ALA VAL MET GLN LEU GLN LYS          
SEQRES  13 6  181  LYS VAL ARG GLY GLN ALA TYR ASN GLU ARG GLY GLU ARG          
SEQRES  14 6  181  LEU PRO PRO VAL ALA ALA TRP LYS ARG THR ARG GLY              
SEQRES   1 9  182  MET THR LEU LYS ALA LEU ALA GLN SER LEU GLY ILE THR          
SEQRES   2 9  182  LEU LYS TYR LEU PHE SER LYS PRO VAL THR VAL PRO TYR          
SEQRES   3 9  182  PRO ASP ALA PRO VAL ALA LEU LYS PRO ARG PHE HIS GLY          
SEQRES   4 9  182  ARG HIS VAL LEU THR ARG HIS PRO ASN GLY LEU GLU LYS          
SEQRES   5 9  182  CYS ILE GLY CYS SER LEU CYS ALA ALA ALA CYS PRO ALA          
SEQRES   6 9  182  TYR ALA ILE TYR VAL GLU PRO ALA GLU ASN ASP PRO GLU          
SEQRES   7 9  182  ASN PRO VAL SER ALA GLY GLU ARG TYR ALA LYS VAL TYR          
SEQRES   8 9  182  GLU ILE ASN MET LEU ARG CYS ILE PHE CYS GLY LEU CYS          
SEQRES   9 9  182  GLU GLU ALA CYS PRO THR GLY ALA ILE VAL LEU GLY TYR          
SEQRES  10 9  182  ASP PHE GLU MET ALA ASP TYR GLU TYR SER ASP LEU VAL          
SEQRES  11 9  182  TYR GLY LYS GLU ASP MET LEU VAL ASP VAL VAL GLY THR          
SEQRES  12 9  182  LYS PRO GLN ARG ARG GLU ALA LYS ARG THR GLY LYS PRO          
SEQRES  13 9  182  VAL LYS VAL GLY TYR VAL VAL PRO TYR VAL ARG PRO GLU          
SEQRES  14 9  182  LEU GLU GLY PHE LYS ALA PRO THR GLU GLY GLY LYS ARG          
SEQRES   1 7  129  MET SER ALA SER SER GLU ARG GLU LEU TYR GLU ALA TRP          
SEQRES   2 7  129  VAL GLU LEU LEU SER TRP MET ARG GLU TYR ALA GLN ALA          
SEQRES   3 7  129  LYS GLY VAL ARG PHE GLU LYS GLU ALA ASP PHE PRO ASP          
SEQRES   4 7  129  PHE ILE TYR ARG MET GLU ARG PRO TYR ASP LEU PRO THR          
SEQRES   5 7  129  THR ILE MET THR ALA SER LEU SER ASP GLY LEU GLY GLU          
SEQRES   6 7  129  PRO PHE LEU LEU ALA ASP VAL SER PRO ARG HIS ALA LYS          
SEQRES   7 7  129  LEU LYS ARG ILE GLY LEU ARG LEU PRO ARG ALA HIS ILE          
SEQRES   8 7  129  HIS LEU HIS ALA HIS TYR GLU PRO GLY LYS GLY LEU VAL          
SEQRES   9 7  129  THR GLY LYS ILE PRO LEU THR LYS GLU ARG PHE PHE ALA          
SEQRES  10 7  129  LEU ALA ASP ARG ALA ARG GLU ALA LEU ALA PHE ALA              
SEQRES   1 A  438  MET THR GLY PRO ILE LEU SER GLY LEU ASP PRO ARG PHE          
SEQRES   2 A  438  GLU ARG THR LEU TYR ALA HIS VAL GLY LYS GLU GLY SER          
SEQRES   3 A  438  TRP THR LEU ASP TYR TYR LEU ARG HIS GLY GLY TYR GLU          
SEQRES   4 A  438  THR ALA LYS ARG VAL LEU LYS GLU LYS THR PRO ASP GLU          
SEQRES   5 A  438  VAL ILE GLU GLU VAL LYS ARG SER GLY LEU ARG GLY ARG          
SEQRES   6 A  438  GLY GLY ALA GLY PHE PRO THR GLY LEU LYS TRP SER PHE          
SEQRES   7 A  438  MET PRO LYS ASP ASP GLY LYS GLN HIS TYR LEU ILE CYS          
SEQRES   8 A  438  ASN ALA ASP GLU SER GLU PRO GLY SER PHE LYS ASP ARG          
SEQRES   9 A  438  TYR ILE LEU GLU ASP VAL PRO HIS LEU LEU ILE GLU GLY          
SEQRES  10 A  438  MET ILE LEU ALA GLY TYR ALA ILE ARG ALA THR VAL GLY          
SEQRES  11 A  438  TYR ILE TYR VAL ARG GLY GLU TYR ARG ARG ALA ALA ASP          
SEQRES  12 A  438  ARG LEU GLU GLN ALA ILE LYS GLU ALA ARG ALA ARG GLY          
SEQRES  13 A  438  TYR LEU GLY LYS ASN LEU PHE GLY THR ASP PHE SER PHE          
SEQRES  14 A  438  ASP LEU HIS VAL HIS ARG GLY ALA GLY ALA TYR ILE CYS          
SEQRES  15 A  438  GLY GLU GLU THR ALA LEU MET ASN SER LEU GLU GLY LEU          
SEQRES  16 A  438  ARG ALA ASN PRO ARG LEU LYS PRO PRO PHE PRO ALA GLN          
SEQRES  17 A  438  SER GLY LEU TRP GLY LYS PRO THR THR ILE ASN ASN VAL          
SEQRES  18 A  438  GLU THR LEU ALA SER VAL VAL PRO ILE MET GLU ARG GLY          
SEQRES  19 A  438  ALA ASP TRP PHE ALA GLN MET GLY THR GLU GLN SER LYS          
SEQRES  20 A  438  GLY MET LYS LEU TYR GLN ILE SER GLY PRO VAL LYS ARG          
SEQRES  21 A  438  PRO GLY VAL TYR GLU LEU PRO MET GLY THR THR PHE ARG          
SEQRES  22 A  438  GLU LEU ILE TYR GLU TRP ALA GLY GLY PRO LEU GLU PRO          
SEQRES  23 A  438  ILE GLN ALA ILE ILE PRO GLY GLY SER SER THR PRO PRO          
SEQRES  24 A  438  LEU PRO PHE THR GLU GLU VAL LEU ASP THR PRO MET SER          
SEQRES  25 A  438  TYR GLU HIS LEU GLN ALA LYS GLY SER MET LEU GLY THR          
SEQRES  26 A  438  GLY GLY VAL ILE LEU ILE PRO GLU ARG VAL SER MET VAL          
SEQRES  27 A  438  ASP ALA MET TRP ASN LEU THR ARG PHE TYR ALA HIS GLU          
SEQRES  28 A  438  SER CYS GLY LYS CYS THR PRO CYS ARG GLU GLY VAL ALA          
SEQRES  29 A  438  GLY PHE MET VAL ASN LEU PHE ALA LYS ILE GLY THR GLY          
SEQRES  30 A  438  GLN GLY GLU GLU LYS ASP VAL GLU ASN LEU GLU ALA LEU          
SEQRES  31 A  438  LEU PRO LEU ILE GLU GLY ARG SER PHE CYS PRO LEU ALA          
SEQRES  32 A  438  ASP ALA ALA VAL TRP PRO VAL LYS GLY SER LEU ARG HIS          
SEQRES  33 A  438  PHE LYS ASP GLN TYR LEU ALA LEU ALA ARG GLU LYS ARG          
SEQRES  34 A  438  PRO VAL PRO ARG PRO SER LEU TRP ARG                          
SEQRES   1 B  181  MET GLY PHE PHE ASP ASP LYS GLN ASP PHE LEU GLU GLU          
SEQRES   2 B  181  THR PHE ALA LYS TYR PRO PRO GLU GLY ARG ARG ALA ALA          
SEQRES   3 B  181  ILE MET PRO LEU LEU ARG ARG VAL GLN GLN GLU GLU GLY          
SEQRES   4 B  181  TRP ILE ARG PRO GLU ARG ILE GLU GLU ILE ALA ARG LEU          
SEQRES   5 B  181  VAL GLY THR THR PRO THR GLU VAL MET GLY VAL ALA SER          
SEQRES   6 B  181  PHE TYR SER TYR TYR GLN PHE VAL PRO THR GLY LYS TYR          
SEQRES   7 B  181  HIS LEU GLN VAL CYS ALA THR LEU SER CYS LYS LEU ALA          
SEQRES   8 B  181  GLY ALA GLU GLU LEU TRP ASP TYR LEU THR GLU THR LEU          
SEQRES   9 B  181  GLY ILE GLY PRO GLY GLU VAL THR PRO ASP GLY LEU PHE          
SEQRES  10 B  181  SER VAL GLN LYS VAL GLU CYS LEU GLY SER CYS HIS THR          
SEQRES  11 B  181  ALA PRO VAL ILE GLN VAL ASN ASP GLU PRO TYR VAL GLU          
SEQRES  12 B  181  CYS VAL THR ARG ALA ARG LEU GLU ALA LEU LEU ALA GLY          
SEQRES  13 B  181  LEU ARG ALA GLY LYS ARG LEU GLU GLU ILE GLU LEU PRO          
SEQRES  14 B  181  GLY LYS CYS GLY HIS HIS VAL HIS GLU VAL GLU VAL              
SEQRES   1 C  783  MET VAL ARG VAL LYS VAL ASN ASP ARG ILE VAL GLU VAL          
SEQRES   2 C  783  PRO PRO GLY THR SER VAL MET ASP ALA VAL PHE HIS ALA          
SEQRES   3 C  783  GLY TYR ASP VAL PRO LEU PHE CYS SER GLU LYS HIS LEU          
SEQRES   4 C  783  SER PRO ILE GLY ALA CYS ARG MET CYS LEU VAL ARG ILE          
SEQRES   5 C  783  GLY LEU PRO LYS LYS GLY PRO ASP GLY LYS PRO LEU LEU          
SEQRES   6 C  783  ASN GLU LYS GLY GLU PRO GLU ILE GLN TRP GLN PRO LYS          
SEQRES   7 C  783  LEU ALA ALA SER CYS VAL THR ALA VAL ALA ASP GLY MET          
SEQRES   8 C  783  VAL VAL ASP THR LEU SER ASP VAL VAL ARG GLU ALA GLN          
SEQRES   9 C  783  ALA GLY MET VAL GLU PHE THR LEU LEU ASN HIS PRO LEU          
SEQRES  10 C  783  ASP CYS PRO THR CYS ASP LYS GLY GLY ALA CYS GLU LEU          
SEQRES  11 C  783  GLN ASP ARG THR VAL GLU TYR GLY LEU TYR GLU LYS TYR          
SEQRES  12 C  783  TYR GLN LYS GLY PRO LEU GLU LEU PRO VAL TYR THR ARG          
SEQRES  13 C  783  PHE GLU PHE THR ARG ARG HIS VAL ASP LYS HIS HIS PRO          
SEQRES  14 C  783  LEU SER PRO PHE VAL ILE LEU ASP ARG GLU ARG CYS ILE          
SEQRES  15 C  783  HIS CYS LYS ARG CYS VAL ARG TYR PHE GLU GLU VAL PRO          
SEQRES  16 C  783  GLY ASP GLU VAL LEU ASP PHE ILE GLU ARG GLY VAL HIS          
SEQRES  17 C  783  THR PHE ILE GLY THR MET ASP PHE GLY LEU PRO SER GLY          
SEQRES  18 C  783  PHE SER GLY ASN ILE THR ASP ILE CYS PRO VAL GLY ALA          
SEQRES  19 C  783  LEU LEU ASP LEU THR ALA ARG PHE ARG ALA ARG ASN TRP          
SEQRES  20 C  783  GLU MET GLU GLU THR PRO THR THR CYS ALA LEU CYS PRO          
SEQRES  21 C  783  VAL GLY CYS GLY ILE THR ALA ASP THR ARG SER GLY GLU          
SEQRES  22 C  783  LEU LEU ARG ILE ARG ALA ARG GLU VAL PRO GLU VAL ASN          
SEQRES  23 C  783  GLU ILE TRP ILE CYS ASP ALA GLY ARG PHE GLY HIS GLU          
SEQRES  24 C  783  TRP ALA ASP GLN ASN ARG LEU LYS THR PRO LEU VAL ARG          
SEQRES  25 C  783  LYS GLU GLY ARG LEU VAL GLU ALA THR TRP GLU GLU ALA          
SEQRES  26 C  783  PHE LEU ALA LEU LYS GLU GLY LEU LYS GLU ALA ARG GLY          
SEQRES  27 C  783  GLU GLU VAL GLY LEU TYR LEU ALA HIS ASP ALA THR LEU          
SEQRES  28 C  783  GLU GLU GLY LEU LEU ALA SER GLU LEU ALA LYS ALA LEU          
SEQRES  29 C  783  LYS THR PRO HIS LEU ASP PHE GLN GLY ARG THR ALA ALA          
SEQRES  30 C  783  PRO ALA SER LEU PHE PRO PRO ALA SER LEU GLU ASP LEU          
SEQRES  31 C  783  LEU GLN ALA ASP PHE ALA LEU VAL LEU GLY ASP PRO THR          
SEQRES  32 C  783  GLU GLU ALA PRO ILE LEU HIS LEU ARG LEU SER GLU PHE          
SEQRES  33 C  783  VAL ARG ASP LEU LYS PRO PRO HIS ARG TYR ASN HIS GLY          
SEQRES  34 C  783  THR PRO PHE ALA ASP LEU GLN ILE LYS GLU ARG MET PRO          
SEQRES  35 C  783  ARG ARG THR ASP LYS MET ALA LEU PHE ALA PRO TYR ARG          
SEQRES  36 C  783  ALA PRO LEU MET LYS TRP ALA ALA ILE HIS GLU VAL HIS          
SEQRES  37 C  783  ARG PRO GLY GLU GLU ARG GLU ILE LEU LEU ALA LEU LEU          
SEQRES  38 C  783  GLY ASP LYS GLU GLY SER GLU MET VAL ALA LYS ALA LYS          
SEQRES  39 C  783  GLU ALA TRP GLU LYS ALA LYS ASN PRO VAL LEU ILE LEU          
SEQRES  40 C  783  GLY ALA GLY VAL LEU GLN ASP THR VAL ALA ALA GLU ARG          
SEQRES  41 C  783  ALA ARG LEU LEU ALA GLU ARG LYS GLY ALA LYS VAL LEU          
SEQRES  42 C  783  ALA MET THR PRO ALA ALA ASN ALA ARG GLY LEU GLU ALA          
SEQRES  43 C  783  MET GLY VAL LEU PRO GLY ALA LYS GLY ALA SER TRP ASP          
SEQRES  44 C  783  GLU PRO GLY ALA LEU TYR ALA TYR TYR GLY PHE VAL PRO          
SEQRES  45 C  783  PRO GLU GLU ALA LEU LYS GLY LYS ARG PHE VAL VAL MET          
SEQRES  46 C  783  HIS LEU SER HIS LEU HIS PRO LEU ALA GLU ARG TYR ALA          
SEQRES  47 C  783  HIS VAL VAL LEU PRO ALA PRO THR PHE TYR GLU LYS ARG          
SEQRES  48 C  783  GLY HIS LEU VAL ASN LEU GLU GLY ARG VAL LEU PRO LEU          
SEQRES  49 C  783  SER PRO ALA PRO ILE GLU ASN GLY GLU ALA GLU GLY ALA          
SEQRES  50 C  783  LEU GLN VAL LEU ALA LEU LEU ALA GLU ALA LEU GLY VAL          
SEQRES  51 C  783  ARG PRO PRO PHE ARG LEU HIS LEU GLU ALA GLN LYS ALA          
SEQRES  52 C  783  LEU LYS ALA ARG LYS VAL PRO GLU ALA MET GLY ARG LEU          
SEQRES  53 C  783  SER PHE ARG LEU LYS GLU LEU ARG PRO LYS GLU ARG LYS          
SEQRES  54 C  783  GLY ALA PHE TYR LEU ARG PRO THR MET TRP LYS ALA HIS          
SEQRES  55 C  783  GLN ALA VAL GLY LYS ALA GLN GLU ALA ALA ARG ALA GLU          
SEQRES  56 C  783  LEU TRP ALA HIS PRO GLU THR ALA ARG ALA GLU ALA LEU          
SEQRES  57 C  783  PRO GLU GLY ALA GLN VAL ALA VAL GLU THR PRO PHE GLY          
SEQRES  58 C  783  ARG VAL GLU ALA ARG VAL VAL HIS ARG GLU ASP VAL PRO          
SEQRES  59 C  783  LYS GLY HIS LEU TYR LEU SER ALA LEU GLY PRO ALA ALA          
SEQRES  60 C  783  GLY LEU ARG VAL GLU GLY ARG VAL LEU VAL PRO ALA GLY          
SEQRES  61 C  783  GLY GLU ALA                                                  
SEQRES   1 D  409  MET ARG GLU GLU PHE LEU GLU GLU ILE PRO LEU ASP ALA          
SEQRES   2 D  409  PRO PRO GLU GLU ALA LYS GLU LEU ARG THR GLU VAL MET          
SEQRES   3 D  409  THR LEU ASN VAL GLY PRO GLN HIS PRO SER THR HIS GLY          
SEQRES   4 D  409  VAL LEU ARG LEU MET VAL THR LEU SER GLY GLU GLU VAL          
SEQRES   5 D  409  LEU GLU VAL VAL PRO HIS ILE GLY TYR LEU HIS THR GLY          
SEQRES   6 D  409  PHE GLU LYS THR MET GLU HIS ARG THR TYR LEU GLN ASN          
SEQRES   7 D  409  ILE THR TYR THR PRO ARG MET ASP TYR LEU HIS SER PHE          
SEQRES   8 D  409  ALA HIS ASP LEU ALA TYR ALA LEU ALA VAL GLU LYS LEU          
SEQRES   9 D  409  LEU GLY ALA VAL VAL PRO PRO ARG ALA GLU THR ILE ARG          
SEQRES  10 D  409  VAL ILE LEU ASN GLU LEU SER ARG LEU ALA SER HIS LEU          
SEQRES  11 D  409  VAL PHE LEU GLY THR GLY LEU LEU ASP LEU GLY ALA LEU          
SEQRES  12 D  409  THR PRO PHE PHE TYR ALA PHE ARG GLU ARG GLU THR ILE          
SEQRES  13 D  409  LEU ASP LEU PHE GLU TRP VAL THR GLY GLN ARG PHE HIS          
SEQRES  14 D  409  HIS ASN TYR ILE ARG ILE GLY GLY VAL LYS GLU ASP LEU          
SEQRES  15 D  409  PRO GLU GLU PHE VAL PRO GLU LEU LYS LYS LEU LEU GLU          
SEQRES  16 D  409  VAL LEU PRO HIS ARG ILE ASP GLU TYR GLU ALA LEU PHE          
SEQRES  17 D  409  ALA GLU SER PRO ILE PHE TYR GLU ARG ALA ARG GLY VAL          
SEQRES  18 D  409  GLY VAL ILE PRO PRO GLU VAL ALA ILE ASP LEU GLY LEU          
SEQRES  19 D  409  THR GLY GLY SER LEU ARG ALA SER GLY VAL ASN TYR ASP          
SEQRES  20 D  409  VAL ARG LYS ALA TYR PRO TYR SER GLY TYR GLU THR TYR          
SEQRES  21 D  409  THR PHE ASP VAL PRO LEU GLY GLU ARG GLY ASP VAL PHE          
SEQRES  22 D  409  ASP ARG MET LEU VAL ARG ILE ARG GLU MET ARG GLU SER          
SEQRES  23 D  409  VAL LYS ILE ILE LYS GLN ALA LEU GLU ARG LEU GLU PRO          
SEQRES  24 D  409  GLY PRO VAL ARG ASP PRO ASN PRO GLN ILE THR PRO PRO          
SEQRES  25 D  409  PRO ARG HIS LEU LEU GLU THR SER MET GLU ALA VAL ILE          
SEQRES  26 D  409  TYR HIS PHE LYS HIS TYR THR GLU GLY PHE HIS PRO PRO          
SEQRES  27 D  409  LYS GLY GLU VAL TYR VAL PRO THR GLU SER ALA ARG GLY          
SEQRES  28 D  409  GLU LEU GLY TYR TYR ILE VAL SER ASP GLY GLY SER MET          
SEQRES  29 D  409  PRO TYR ARG VAL LYS VAL ARG ALA PRO SER PHE VAL ASN          
SEQRES  30 D  409  LEU GLN SER LEU PRO TYR ALA CYS LYS GLY GLU GLN VAL          
SEQRES  31 D  409  PRO ASP MET VAL ALA ILE ILE ALA SER LEU ASP PRO VAL          
SEQRES  32 D  409  MET GLY ASP VAL ASP ARG                                      
SEQRES   1 E  207  MET ARG LEU GLU ARG VAL LEU GLU GLU ALA ARG ALA LYS          
SEQRES   2 E  207  GLY TYR PRO ILE GLU ASP ASN GLY LEU GLY ASN LEU TRP          
SEQRES   3 E  207  VAL VAL LEU PRO ARG GLU ARG PHE LYS GLU GLU MET ALA          
SEQRES   4 E  207  HIS TYR LYS ALA MET GLY PHE ASN PHE LEU ALA ASP ILE          
SEQRES   5 E  207  VAL GLY LEU ASP TYR LEU THR TYR PRO ASP PRO ARG PRO          
SEQRES   6 E  207  GLU ARG PHE ALA VAL VAL TYR GLU LEU VAL SER LEU PRO          
SEQRES   7 E  207  GLY TRP LYS ASP GLY ASP GLY SER ARG PHE PHE VAL ARG          
SEQRES   8 E  207  VAL TYR VAL PRO GLU GLU ASP PRO ARG LEU PRO THR VAL          
SEQRES   9 E  207  THR ASP LEU TRP GLY SER ALA ASN PHE LEU GLU ARG GLU          
SEQRES  10 E  207  VAL TYR ASP LEU PHE GLY ILE VAL PHE GLU GLY HIS PRO          
SEQRES  11 E  207  ASP LEU ARG LYS ILE LEU THR PRO GLU ASP LEU GLU GLY          
SEQRES  12 E  207  HIS PRO LEU ARG LYS ASP TYR PRO LEU GLY GLU THR PRO          
SEQRES  13 E  207  THR LEU PHE ARG GLU GLY ARG TYR ILE ILE PRO ALA GLU          
SEQRES  14 E  207  PHE ARG ALA ALA LEU THR GLY LYS ASP PRO GLY LEU THR          
SEQRES  15 E  207  PHE TYR LYS GLY GLY SER ARG LYS GLY TYR ARG SER LEU          
SEQRES  16 E  207  TRP ALA ASP LEU LYS LYS ALA ARG GLU VAL LYS GLY              
SEQRES   1 F  181  MET ALA LEU LYS ASP LEU PHE GLU ARG ASP VAL GLN GLU          
SEQRES   2 F  181  LEU GLU ARG GLU GLY ILE LEU PHE THR THR LEU GLU LYS          
SEQRES   3 F  181  LEU VAL ALA TRP GLY ARG SER ASN SER LEU TRP PRO ALA          
SEQRES   4 F  181  THR PHE GLY LEU ALA CYS CYS ALA ILE GLU MET MET ALA          
SEQRES   5 F  181  SER THR ASP ALA ARG ASN ASP LEU ALA ARG PHE GLY SER          
SEQRES   6 F  181  GLU VAL PHE ARG ALA SER PRO ARG GLN ALA ASP VAL MET          
SEQRES   7 F  181  ILE VAL ALA GLY ARG LEU SER LYS LYS MET ALA PRO VAL          
SEQRES   8 F  181  MET ARG ARG VAL TRP GLU GLN MET PRO ASP PRO LYS TRP          
SEQRES   9 F  181  VAL ILE SER MET GLY ALA CYS ALA SER SER GLY GLY MET          
SEQRES  10 F  181  PHE ASN ASN TYR ALA ILE VAL GLN ASN VAL ASP SER VAL          
SEQRES  11 F  181  VAL PRO VAL ASP VAL TYR VAL PRO GLY CYS PRO PRO ARG          
SEQRES  12 F  181  PRO GLU ALA LEU ILE TYR ALA VAL MET GLN LEU GLN LYS          
SEQRES  13 F  181  LYS VAL ARG GLY GLN ALA TYR ASN GLU ARG GLY GLU ARG          
SEQRES  14 F  181  LEU PRO PRO VAL ALA ALA TRP LYS ARG THR ARG GLY              
SEQRES   1 G  182  MET THR LEU LYS ALA LEU ALA GLN SER LEU GLY ILE THR          
SEQRES   2 G  182  LEU LYS TYR LEU PHE SER LYS PRO VAL THR VAL PRO TYR          
SEQRES   3 G  182  PRO ASP ALA PRO VAL ALA LEU LYS PRO ARG PHE HIS GLY          
SEQRES   4 G  182  ARG HIS VAL LEU THR ARG HIS PRO ASN GLY LEU GLU LYS          
SEQRES   5 G  182  CYS ILE GLY CYS SER LEU CYS ALA ALA ALA CYS PRO ALA          
SEQRES   6 G  182  TYR ALA ILE TYR VAL GLU PRO ALA GLU ASN ASP PRO GLU          
SEQRES   7 G  182  ASN PRO VAL SER ALA GLY GLU ARG TYR ALA LYS VAL TYR          
SEQRES   8 G  182  GLU ILE ASN MET LEU ARG CYS ILE PHE CYS GLY LEU CYS          
SEQRES   9 G  182  GLU GLU ALA CYS PRO THR GLY ALA ILE VAL LEU GLY TYR          
SEQRES  10 G  182  ASP PHE GLU MET ALA ASP TYR GLU TYR SER ASP LEU VAL          
SEQRES  11 G  182  TYR GLY LYS GLU ASP MET LEU VAL ASP VAL VAL GLY THR          
SEQRES  12 G  182  LYS PRO GLN ARG ARG GLU ALA LYS ARG THR GLY LYS PRO          
SEQRES  13 G  182  VAL LYS VAL GLY TYR VAL VAL PRO TYR VAL ARG PRO GLU          
SEQRES  14 G  182  LEU GLU GLY PHE LYS ALA PRO THR GLU GLY GLY LYS ARG          
SEQRES   1 H  129  MET SER ALA SER SER GLU ARG GLU LEU TYR GLU ALA TRP          
SEQRES   2 H  129  VAL GLU LEU LEU SER TRP MET ARG GLU TYR ALA GLN ALA          
SEQRES   3 H  129  LYS GLY VAL ARG PHE GLU LYS GLU ALA ASP PHE PRO ASP          
SEQRES   4 H  129  PHE ILE TYR ARG MET GLU ARG PRO TYR ASP LEU PRO THR          
SEQRES   5 H  129  THR ILE MET THR ALA SER LEU SER ASP GLY LEU GLY GLU          
SEQRES   6 H  129  PRO PHE LEU LEU ALA ASP VAL SER PRO ARG HIS ALA LYS          
SEQRES   7 H  129  LEU LYS ARG ILE GLY LEU ARG LEU PRO ARG ALA HIS ILE          
SEQRES   8 H  129  HIS LEU HIS ALA HIS TYR GLU PRO GLY LYS GLY LEU VAL          
SEQRES   9 H  129  THR GLY LYS ILE PRO LEU THR LYS GLU ARG PHE PHE ALA          
SEQRES  10 H  129  LEU ALA ASP ARG ALA ARG GLU ALA LEU ALA PHE ALA              
SEQRES   1 J  438  MET THR GLY PRO ILE LEU SER GLY LEU ASP PRO ARG PHE          
SEQRES   2 J  438  GLU ARG THR LEU TYR ALA HIS VAL GLY LYS GLU GLY SER          
SEQRES   3 J  438  TRP THR LEU ASP TYR TYR LEU ARG HIS GLY GLY TYR GLU          
SEQRES   4 J  438  THR ALA LYS ARG VAL LEU LYS GLU LYS THR PRO ASP GLU          
SEQRES   5 J  438  VAL ILE GLU GLU VAL LYS ARG SER GLY LEU ARG GLY ARG          
SEQRES   6 J  438  GLY GLY ALA GLY PHE PRO THR GLY LEU LYS TRP SER PHE          
SEQRES   7 J  438  MET PRO LYS ASP ASP GLY LYS GLN HIS TYR LEU ILE CYS          
SEQRES   8 J  438  ASN ALA ASP GLU SER GLU PRO GLY SER PHE LYS ASP ARG          
SEQRES   9 J  438  TYR ILE LEU GLU ASP VAL PRO HIS LEU LEU ILE GLU GLY          
SEQRES  10 J  438  MET ILE LEU ALA GLY TYR ALA ILE ARG ALA THR VAL GLY          
SEQRES  11 J  438  TYR ILE TYR VAL ARG GLY GLU TYR ARG ARG ALA ALA ASP          
SEQRES  12 J  438  ARG LEU GLU GLN ALA ILE LYS GLU ALA ARG ALA ARG GLY          
SEQRES  13 J  438  TYR LEU GLY LYS ASN LEU PHE GLY THR ASP PHE SER PHE          
SEQRES  14 J  438  ASP LEU HIS VAL HIS ARG GLY ALA GLY ALA TYR ILE CYS          
SEQRES  15 J  438  GLY GLU GLU THR ALA LEU MET ASN SER LEU GLU GLY LEU          
SEQRES  16 J  438  ARG ALA ASN PRO ARG LEU LYS PRO PRO PHE PRO ALA GLN          
SEQRES  17 J  438  SER GLY LEU TRP GLY LYS PRO THR THR ILE ASN ASN VAL          
SEQRES  18 J  438  GLU THR LEU ALA SER VAL VAL PRO ILE MET GLU ARG GLY          
SEQRES  19 J  438  ALA ASP TRP PHE ALA GLN MET GLY THR GLU GLN SER LYS          
SEQRES  20 J  438  GLY MET LYS LEU TYR GLN ILE SER GLY PRO VAL LYS ARG          
SEQRES  21 J  438  PRO GLY VAL TYR GLU LEU PRO MET GLY THR THR PHE ARG          
SEQRES  22 J  438  GLU LEU ILE TYR GLU TRP ALA GLY GLY PRO LEU GLU PRO          
SEQRES  23 J  438  ILE GLN ALA ILE ILE PRO GLY GLY SER SER THR PRO PRO          
SEQRES  24 J  438  LEU PRO PHE THR GLU GLU VAL LEU ASP THR PRO MET SER          
SEQRES  25 J  438  TYR GLU HIS LEU GLN ALA LYS GLY SER MET LEU GLY THR          
SEQRES  26 J  438  GLY GLY VAL ILE LEU ILE PRO GLU ARG VAL SER MET VAL          
SEQRES  27 J  438  ASP ALA MET TRP ASN LEU THR ARG PHE TYR ALA HIS GLU          
SEQRES  28 J  438  SER CYS GLY LYS CYS THR PRO CYS ARG GLU GLY VAL ALA          
SEQRES  29 J  438  GLY PHE MET VAL ASN LEU PHE ALA LYS ILE GLY THR GLY          
SEQRES  30 J  438  GLN GLY GLU GLU LYS ASP VAL GLU ASN LEU GLU ALA LEU          
SEQRES  31 J  438  LEU PRO LEU ILE GLU GLY ARG SER PHE CYS PRO LEU ALA          
SEQRES  32 J  438  ASP ALA ALA VAL TRP PRO VAL LYS GLY SER LEU ARG HIS          
SEQRES  33 J  438  PHE LYS ASP GLN TYR LEU ALA LEU ALA ARG GLU LYS ARG          
SEQRES  34 J  438  PRO VAL PRO ARG PRO SER LEU TRP ARG                          
SEQRES   1 K  181  MET GLY PHE PHE ASP ASP LYS GLN ASP PHE LEU GLU GLU          
SEQRES   2 K  181  THR PHE ALA LYS TYR PRO PRO GLU GLY ARG ARG ALA ALA          
SEQRES   3 K  181  ILE MET PRO LEU LEU ARG ARG VAL GLN GLN GLU GLU GLY          
SEQRES   4 K  181  TRP ILE ARG PRO GLU ARG ILE GLU GLU ILE ALA ARG LEU          
SEQRES   5 K  181  VAL GLY THR THR PRO THR GLU VAL MET GLY VAL ALA SER          
SEQRES   6 K  181  PHE TYR SER TYR TYR GLN PHE VAL PRO THR GLY LYS TYR          
SEQRES   7 K  181  HIS LEU GLN VAL CYS ALA THR LEU SER CYS LYS LEU ALA          
SEQRES   8 K  181  GLY ALA GLU GLU LEU TRP ASP TYR LEU THR GLU THR LEU          
SEQRES   9 K  181  GLY ILE GLY PRO GLY GLU VAL THR PRO ASP GLY LEU PHE          
SEQRES  10 K  181  SER VAL GLN LYS VAL GLU CYS LEU GLY SER CYS HIS THR          
SEQRES  11 K  181  ALA PRO VAL ILE GLN VAL ASN ASP GLU PRO TYR VAL GLU          
SEQRES  12 K  181  CYS VAL THR ARG ALA ARG LEU GLU ALA LEU LEU ALA GLY          
SEQRES  13 K  181  LEU ARG ALA GLY LYS ARG LEU GLU GLU ILE GLU LEU PRO          
SEQRES  14 K  181  GLY LYS CYS GLY HIS HIS VAL HIS GLU VAL GLU VAL              
SEQRES   1 L  783  MET VAL ARG VAL LYS VAL ASN ASP ARG ILE VAL GLU VAL          
SEQRES   2 L  783  PRO PRO GLY THR SER VAL MET ASP ALA VAL PHE HIS ALA          
SEQRES   3 L  783  GLY TYR ASP VAL PRO LEU PHE CYS SER GLU LYS HIS LEU          
SEQRES   4 L  783  SER PRO ILE GLY ALA CYS ARG MET CYS LEU VAL ARG ILE          
SEQRES   5 L  783  GLY LEU PRO LYS LYS GLY PRO ASP GLY LYS PRO LEU LEU          
SEQRES   6 L  783  ASN GLU LYS GLY GLU PRO GLU ILE GLN TRP GLN PRO LYS          
SEQRES   7 L  783  LEU ALA ALA SER CYS VAL THR ALA VAL ALA ASP GLY MET          
SEQRES   8 L  783  VAL VAL ASP THR LEU SER ASP VAL VAL ARG GLU ALA GLN          
SEQRES   9 L  783  ALA GLY MET VAL GLU PHE THR LEU LEU ASN HIS PRO LEU          
SEQRES  10 L  783  ASP CYS PRO THR CYS ASP LYS GLY GLY ALA CYS GLU LEU          
SEQRES  11 L  783  GLN ASP ARG THR VAL GLU TYR GLY LEU TYR GLU LYS TYR          
SEQRES  12 L  783  TYR GLN LYS GLY PRO LEU GLU LEU PRO VAL TYR THR ARG          
SEQRES  13 L  783  PHE GLU PHE THR ARG ARG HIS VAL ASP LYS HIS HIS PRO          
SEQRES  14 L  783  LEU SER PRO PHE VAL ILE LEU ASP ARG GLU ARG CYS ILE          
SEQRES  15 L  783  HIS CYS LYS ARG CYS VAL ARG TYR PHE GLU GLU VAL PRO          
SEQRES  16 L  783  GLY ASP GLU VAL LEU ASP PHE ILE GLU ARG GLY VAL HIS          
SEQRES  17 L  783  THR PHE ILE GLY THR MET ASP PHE GLY LEU PRO SER GLY          
SEQRES  18 L  783  PHE SER GLY ASN ILE THR ASP ILE CYS PRO VAL GLY ALA          
SEQRES  19 L  783  LEU LEU ASP LEU THR ALA ARG PHE ARG ALA ARG ASN TRP          
SEQRES  20 L  783  GLU MET GLU GLU THR PRO THR THR CYS ALA LEU CYS PRO          
SEQRES  21 L  783  VAL GLY CYS GLY ILE THR ALA ASP THR ARG SER GLY GLU          
SEQRES  22 L  783  LEU LEU ARG ILE ARG ALA ARG GLU VAL PRO GLU VAL ASN          
SEQRES  23 L  783  GLU ILE TRP ILE CYS ASP ALA GLY ARG PHE GLY HIS GLU          
SEQRES  24 L  783  TRP ALA ASP GLN ASN ARG LEU LYS THR PRO LEU VAL ARG          
SEQRES  25 L  783  LYS GLU GLY ARG LEU VAL GLU ALA THR TRP GLU GLU ALA          
SEQRES  26 L  783  PHE LEU ALA LEU LYS GLU GLY LEU LYS GLU ALA ARG GLY          
SEQRES  27 L  783  GLU GLU VAL GLY LEU TYR LEU ALA HIS ASP ALA THR LEU          
SEQRES  28 L  783  GLU GLU GLY LEU LEU ALA SER GLU LEU ALA LYS ALA LEU          
SEQRES  29 L  783  LYS THR PRO HIS LEU ASP PHE GLN GLY ARG THR ALA ALA          
SEQRES  30 L  783  PRO ALA SER LEU PHE PRO PRO ALA SER LEU GLU ASP LEU          
SEQRES  31 L  783  LEU GLN ALA ASP PHE ALA LEU VAL LEU GLY ASP PRO THR          
SEQRES  32 L  783  GLU GLU ALA PRO ILE LEU HIS LEU ARG LEU SER GLU PHE          
SEQRES  33 L  783  VAL ARG ASP LEU LYS PRO PRO HIS ARG TYR ASN HIS GLY          
SEQRES  34 L  783  THR PRO PHE ALA ASP LEU GLN ILE LYS GLU ARG MET PRO          
SEQRES  35 L  783  ARG ARG THR ASP LYS MET ALA LEU PHE ALA PRO TYR ARG          
SEQRES  36 L  783  ALA PRO LEU MET LYS TRP ALA ALA ILE HIS GLU VAL HIS          
SEQRES  37 L  783  ARG PRO GLY GLU GLU ARG GLU ILE LEU LEU ALA LEU LEU          
SEQRES  38 L  783  GLY ASP LYS GLU GLY SER GLU MET VAL ALA LYS ALA LYS          
SEQRES  39 L  783  GLU ALA TRP GLU LYS ALA LYS ASN PRO VAL LEU ILE LEU          
SEQRES  40 L  783  GLY ALA GLY VAL LEU GLN ASP THR VAL ALA ALA GLU ARG          
SEQRES  41 L  783  ALA ARG LEU LEU ALA GLU ARG LYS GLY ALA LYS VAL LEU          
SEQRES  42 L  783  ALA MET THR PRO ALA ALA ASN ALA ARG GLY LEU GLU ALA          
SEQRES  43 L  783  MET GLY VAL LEU PRO GLY ALA LYS GLY ALA SER TRP ASP          
SEQRES  44 L  783  GLU PRO GLY ALA LEU TYR ALA TYR TYR GLY PHE VAL PRO          
SEQRES  45 L  783  PRO GLU GLU ALA LEU LYS GLY LYS ARG PHE VAL VAL MET          
SEQRES  46 L  783  HIS LEU SER HIS LEU HIS PRO LEU ALA GLU ARG TYR ALA          
SEQRES  47 L  783  HIS VAL VAL LEU PRO ALA PRO THR PHE TYR GLU LYS ARG          
SEQRES  48 L  783  GLY HIS LEU VAL ASN LEU GLU GLY ARG VAL LEU PRO LEU          
SEQRES  49 L  783  SER PRO ALA PRO ILE GLU ASN GLY GLU ALA GLU GLY ALA          
SEQRES  50 L  783  LEU GLN VAL LEU ALA LEU LEU ALA GLU ALA LEU GLY VAL          
SEQRES  51 L  783  ARG PRO PRO PHE ARG LEU HIS LEU GLU ALA GLN LYS ALA          
SEQRES  52 L  783  LEU LYS ALA ARG LYS VAL PRO GLU ALA MET GLY ARG LEU          
SEQRES  53 L  783  SER PHE ARG LEU LYS GLU LEU ARG PRO LYS GLU ARG LYS          
SEQRES  54 L  783  GLY ALA PHE TYR LEU ARG PRO THR MET TRP LYS ALA HIS          
SEQRES  55 L  783  GLN ALA VAL GLY LYS ALA GLN GLU ALA ALA ARG ALA GLU          
SEQRES  56 L  783  LEU TRP ALA HIS PRO GLU THR ALA ARG ALA GLU ALA LEU          
SEQRES  57 L  783  PRO GLU GLY ALA GLN VAL ALA VAL GLU THR PRO PHE GLY          
SEQRES  58 L  783  ARG VAL GLU ALA ARG VAL VAL HIS ARG GLU ASP VAL PRO          
SEQRES  59 L  783  LYS GLY HIS LEU TYR LEU SER ALA LEU GLY PRO ALA ALA          
SEQRES  60 L  783  GLY LEU ARG VAL GLU GLY ARG VAL LEU VAL PRO ALA GLY          
SEQRES  61 L  783  GLY GLU ALA                                                  
SEQRES   1 M  409  MET ARG GLU GLU PHE LEU GLU GLU ILE PRO LEU ASP ALA          
SEQRES   2 M  409  PRO PRO GLU GLU ALA LYS GLU LEU ARG THR GLU VAL MET          
SEQRES   3 M  409  THR LEU ASN VAL GLY PRO GLN HIS PRO SER THR HIS GLY          
SEQRES   4 M  409  VAL LEU ARG LEU MET VAL THR LEU SER GLY GLU GLU VAL          
SEQRES   5 M  409  LEU GLU VAL VAL PRO HIS ILE GLY TYR LEU HIS THR GLY          
SEQRES   6 M  409  PHE GLU LYS THR MET GLU HIS ARG THR TYR LEU GLN ASN          
SEQRES   7 M  409  ILE THR TYR THR PRO ARG MET ASP TYR LEU HIS SER PHE          
SEQRES   8 M  409  ALA HIS ASP LEU ALA TYR ALA LEU ALA VAL GLU LYS LEU          
SEQRES   9 M  409  LEU GLY ALA VAL VAL PRO PRO ARG ALA GLU THR ILE ARG          
SEQRES  10 M  409  VAL ILE LEU ASN GLU LEU SER ARG LEU ALA SER HIS LEU          
SEQRES  11 M  409  VAL PHE LEU GLY THR GLY LEU LEU ASP LEU GLY ALA LEU          
SEQRES  12 M  409  THR PRO PHE PHE TYR ALA PHE ARG GLU ARG GLU THR ILE          
SEQRES  13 M  409  LEU ASP LEU PHE GLU TRP VAL THR GLY GLN ARG PHE HIS          
SEQRES  14 M  409  HIS ASN TYR ILE ARG ILE GLY GLY VAL LYS GLU ASP LEU          
SEQRES  15 M  409  PRO GLU GLU PHE VAL PRO GLU LEU LYS LYS LEU LEU GLU          
SEQRES  16 M  409  VAL LEU PRO HIS ARG ILE ASP GLU TYR GLU ALA LEU PHE          
SEQRES  17 M  409  ALA GLU SER PRO ILE PHE TYR GLU ARG ALA ARG GLY VAL          
SEQRES  18 M  409  GLY VAL ILE PRO PRO GLU VAL ALA ILE ASP LEU GLY LEU          
SEQRES  19 M  409  THR GLY GLY SER LEU ARG ALA SER GLY VAL ASN TYR ASP          
SEQRES  20 M  409  VAL ARG LYS ALA TYR PRO TYR SER GLY TYR GLU THR TYR          
SEQRES  21 M  409  THR PHE ASP VAL PRO LEU GLY GLU ARG GLY ASP VAL PHE          
SEQRES  22 M  409  ASP ARG MET LEU VAL ARG ILE ARG GLU MET ARG GLU SER          
SEQRES  23 M  409  VAL LYS ILE ILE LYS GLN ALA LEU GLU ARG LEU GLU PRO          
SEQRES  24 M  409  GLY PRO VAL ARG ASP PRO ASN PRO GLN ILE THR PRO PRO          
SEQRES  25 M  409  PRO ARG HIS LEU LEU GLU THR SER MET GLU ALA VAL ILE          
SEQRES  26 M  409  TYR HIS PHE LYS HIS TYR THR GLU GLY PHE HIS PRO PRO          
SEQRES  27 M  409  LYS GLY GLU VAL TYR VAL PRO THR GLU SER ALA ARG GLY          
SEQRES  28 M  409  GLU LEU GLY TYR TYR ILE VAL SER ASP GLY GLY SER MET          
SEQRES  29 M  409  PRO TYR ARG VAL LYS VAL ARG ALA PRO SER PHE VAL ASN          
SEQRES  30 M  409  LEU GLN SER LEU PRO TYR ALA CYS LYS GLY GLU GLN VAL          
SEQRES  31 M  409  PRO ASP MET VAL ALA ILE ILE ALA SER LEU ASP PRO VAL          
SEQRES  32 M  409  MET GLY ASP VAL ASP ARG                                      
SEQRES   1 N  207  MET ARG LEU GLU ARG VAL LEU GLU GLU ALA ARG ALA LYS          
SEQRES   2 N  207  GLY TYR PRO ILE GLU ASP ASN GLY LEU GLY ASN LEU TRP          
SEQRES   3 N  207  VAL VAL LEU PRO ARG GLU ARG PHE LYS GLU GLU MET ALA          
SEQRES   4 N  207  HIS TYR LYS ALA MET GLY PHE ASN PHE LEU ALA ASP ILE          
SEQRES   5 N  207  VAL GLY LEU ASP TYR LEU THR TYR PRO ASP PRO ARG PRO          
SEQRES   6 N  207  GLU ARG PHE ALA VAL VAL TYR GLU LEU VAL SER LEU PRO          
SEQRES   7 N  207  GLY TRP LYS ASP GLY ASP GLY SER ARG PHE PHE VAL ARG          
SEQRES   8 N  207  VAL TYR VAL PRO GLU GLU ASP PRO ARG LEU PRO THR VAL          
SEQRES   9 N  207  THR ASP LEU TRP GLY SER ALA ASN PHE LEU GLU ARG GLU          
SEQRES  10 N  207  VAL TYR ASP LEU PHE GLY ILE VAL PHE GLU GLY HIS PRO          
SEQRES  11 N  207  ASP LEU ARG LYS ILE LEU THR PRO GLU ASP LEU GLU GLY          
SEQRES  12 N  207  HIS PRO LEU ARG LYS ASP TYR PRO LEU GLY GLU THR PRO          
SEQRES  13 N  207  THR LEU PHE ARG GLU GLY ARG TYR ILE ILE PRO ALA GLU          
SEQRES  14 N  207  PHE ARG ALA ALA LEU THR GLY LYS ASP PRO GLY LEU THR          
SEQRES  15 N  207  PHE TYR LYS GLY GLY SER ARG LYS GLY TYR ARG SER LEU          
SEQRES  16 N  207  TRP ALA ASP LEU LYS LYS ALA ARG GLU VAL LYS GLY              
SEQRES   1 O  181  MET ALA LEU LYS ASP LEU PHE GLU ARG ASP VAL GLN GLU          
SEQRES   2 O  181  LEU GLU ARG GLU GLY ILE LEU PHE THR THR LEU GLU LYS          
SEQRES   3 O  181  LEU VAL ALA TRP GLY ARG SER ASN SER LEU TRP PRO ALA          
SEQRES   4 O  181  THR PHE GLY LEU ALA CYS CYS ALA ILE GLU MET MET ALA          
SEQRES   5 O  181  SER THR ASP ALA ARG ASN ASP LEU ALA ARG PHE GLY SER          
SEQRES   6 O  181  GLU VAL PHE ARG ALA SER PRO ARG GLN ALA ASP VAL MET          
SEQRES   7 O  181  ILE VAL ALA GLY ARG LEU SER LYS LYS MET ALA PRO VAL          
SEQRES   8 O  181  MET ARG ARG VAL TRP GLU GLN MET PRO ASP PRO LYS TRP          
SEQRES   9 O  181  VAL ILE SER MET GLY ALA CYS ALA SER SER GLY GLY MET          
SEQRES  10 O  181  PHE ASN ASN TYR ALA ILE VAL GLN ASN VAL ASP SER VAL          
SEQRES  11 O  181  VAL PRO VAL ASP VAL TYR VAL PRO GLY CYS PRO PRO ARG          
SEQRES  12 O  181  PRO GLU ALA LEU ILE TYR ALA VAL MET GLN LEU GLN LYS          
SEQRES  13 O  181  LYS VAL ARG GLY GLN ALA TYR ASN GLU ARG GLY GLU ARG          
SEQRES  14 O  181  LEU PRO PRO VAL ALA ALA TRP LYS ARG THR ARG GLY              
SEQRES   1 P  182  MET THR LEU LYS ALA LEU ALA GLN SER LEU GLY ILE THR          
SEQRES   2 P  182  LEU LYS TYR LEU PHE SER LYS PRO VAL THR VAL PRO TYR          
SEQRES   3 P  182  PRO ASP ALA PRO VAL ALA LEU LYS PRO ARG PHE HIS GLY          
SEQRES   4 P  182  ARG HIS VAL LEU THR ARG HIS PRO ASN GLY LEU GLU LYS          
SEQRES   5 P  182  CYS ILE GLY CYS SER LEU CYS ALA ALA ALA CYS PRO ALA          
SEQRES   6 P  182  TYR ALA ILE TYR VAL GLU PRO ALA GLU ASN ASP PRO GLU          
SEQRES   7 P  182  ASN PRO VAL SER ALA GLY GLU ARG TYR ALA LYS VAL TYR          
SEQRES   8 P  182  GLU ILE ASN MET LEU ARG CYS ILE PHE CYS GLY LEU CYS          
SEQRES   9 P  182  GLU GLU ALA CYS PRO THR GLY ALA ILE VAL LEU GLY TYR          
SEQRES  10 P  182  ASP PHE GLU MET ALA ASP TYR GLU TYR SER ASP LEU VAL          
SEQRES  11 P  182  TYR GLY LYS GLU ASP MET LEU VAL ASP VAL VAL GLY THR          
SEQRES  12 P  182  LYS PRO GLN ARG ARG GLU ALA LYS ARG THR GLY LYS PRO          
SEQRES  13 P  182  VAL LYS VAL GLY TYR VAL VAL PRO TYR VAL ARG PRO GLU          
SEQRES  14 P  182  LEU GLU GLY PHE LYS ALA PRO THR GLU GLY GLY LYS ARG          
SEQRES   1 Q  129  MET SER ALA SER SER GLU ARG GLU LEU TYR GLU ALA TRP          
SEQRES   2 Q  129  VAL GLU LEU LEU SER TRP MET ARG GLU TYR ALA GLN ALA          
SEQRES   3 Q  129  LYS GLY VAL ARG PHE GLU LYS GLU ALA ASP PHE PRO ASP          
SEQRES   4 Q  129  PHE ILE TYR ARG MET GLU ARG PRO TYR ASP LEU PRO THR          
SEQRES   5 Q  129  THR ILE MET THR ALA SER LEU SER ASP GLY LEU GLY GLU          
SEQRES   6 Q  129  PRO PHE LEU LEU ALA ASP VAL SER PRO ARG HIS ALA LYS          
SEQRES   7 Q  129  LEU LYS ARG ILE GLY LEU ARG LEU PRO ARG ALA HIS ILE          
SEQRES   8 Q  129  HIS LEU HIS ALA HIS TYR GLU PRO GLY LYS GLY LEU VAL          
SEQRES   9 Q  129  THR GLY LYS ILE PRO LEU THR LYS GLU ARG PHE PHE ALA          
SEQRES  10 Q  129  LEU ALA ASP ARG ALA ARG GLU ALA LEU ALA PHE ALA              
SEQRES   1 S  438  MET THR GLY PRO ILE LEU SER GLY LEU ASP PRO ARG PHE          
SEQRES   2 S  438  GLU ARG THR LEU TYR ALA HIS VAL GLY LYS GLU GLY SER          
SEQRES   3 S  438  TRP THR LEU ASP TYR TYR LEU ARG HIS GLY GLY TYR GLU          
SEQRES   4 S  438  THR ALA LYS ARG VAL LEU LYS GLU LYS THR PRO ASP GLU          
SEQRES   5 S  438  VAL ILE GLU GLU VAL LYS ARG SER GLY LEU ARG GLY ARG          
SEQRES   6 S  438  GLY GLY ALA GLY PHE PRO THR GLY LEU LYS TRP SER PHE          
SEQRES   7 S  438  MET PRO LYS ASP ASP GLY LYS GLN HIS TYR LEU ILE CYS          
SEQRES   8 S  438  ASN ALA ASP GLU SER GLU PRO GLY SER PHE LYS ASP ARG          
SEQRES   9 S  438  TYR ILE LEU GLU ASP VAL PRO HIS LEU LEU ILE GLU GLY          
SEQRES  10 S  438  MET ILE LEU ALA GLY TYR ALA ILE ARG ALA THR VAL GLY          
SEQRES  11 S  438  TYR ILE TYR VAL ARG GLY GLU TYR ARG ARG ALA ALA ASP          
SEQRES  12 S  438  ARG LEU GLU GLN ALA ILE LYS GLU ALA ARG ALA ARG GLY          
SEQRES  13 S  438  TYR LEU GLY LYS ASN LEU PHE GLY THR ASP PHE SER PHE          
SEQRES  14 S  438  ASP LEU HIS VAL HIS ARG GLY ALA GLY ALA TYR ILE CYS          
SEQRES  15 S  438  GLY GLU GLU THR ALA LEU MET ASN SER LEU GLU GLY LEU          
SEQRES  16 S  438  ARG ALA ASN PRO ARG LEU LYS PRO PRO PHE PRO ALA GLN          
SEQRES  17 S  438  SER GLY LEU TRP GLY LYS PRO THR THR ILE ASN ASN VAL          
SEQRES  18 S  438  GLU THR LEU ALA SER VAL VAL PRO ILE MET GLU ARG GLY          
SEQRES  19 S  438  ALA ASP TRP PHE ALA GLN MET GLY THR GLU GLN SER LYS          
SEQRES  20 S  438  GLY MET LYS LEU TYR GLN ILE SER GLY PRO VAL LYS ARG          
SEQRES  21 S  438  PRO GLY VAL TYR GLU LEU PRO MET GLY THR THR PHE ARG          
SEQRES  22 S  438  GLU LEU ILE TYR GLU TRP ALA GLY GLY PRO LEU GLU PRO          
SEQRES  23 S  438  ILE GLN ALA ILE ILE PRO GLY GLY SER SER THR PRO PRO          
SEQRES  24 S  438  LEU PRO PHE THR GLU GLU VAL LEU ASP THR PRO MET SER          
SEQRES  25 S  438  TYR GLU HIS LEU GLN ALA LYS GLY SER MET LEU GLY THR          
SEQRES  26 S  438  GLY GLY VAL ILE LEU ILE PRO GLU ARG VAL SER MET VAL          
SEQRES  27 S  438  ASP ALA MET TRP ASN LEU THR ARG PHE TYR ALA HIS GLU          
SEQRES  28 S  438  SER CYS GLY LYS CYS THR PRO CYS ARG GLU GLY VAL ALA          
SEQRES  29 S  438  GLY PHE MET VAL ASN LEU PHE ALA LYS ILE GLY THR GLY          
SEQRES  30 S  438  GLN GLY GLU GLU LYS ASP VAL GLU ASN LEU GLU ALA LEU          
SEQRES  31 S  438  LEU PRO LEU ILE GLU GLY ARG SER PHE CYS PRO LEU ALA          
SEQRES  32 S  438  ASP ALA ALA VAL TRP PRO VAL LYS GLY SER LEU ARG HIS          
SEQRES  33 S  438  PHE LYS ASP GLN TYR LEU ALA LEU ALA ARG GLU LYS ARG          
SEQRES  34 S  438  PRO VAL PRO ARG PRO SER LEU TRP ARG                          
SEQRES   1 T  181  MET GLY PHE PHE ASP ASP LYS GLN ASP PHE LEU GLU GLU          
SEQRES   2 T  181  THR PHE ALA LYS TYR PRO PRO GLU GLY ARG ARG ALA ALA          
SEQRES   3 T  181  ILE MET PRO LEU LEU ARG ARG VAL GLN GLN GLU GLU GLY          
SEQRES   4 T  181  TRP ILE ARG PRO GLU ARG ILE GLU GLU ILE ALA ARG LEU          
SEQRES   5 T  181  VAL GLY THR THR PRO THR GLU VAL MET GLY VAL ALA SER          
SEQRES   6 T  181  PHE TYR SER TYR TYR GLN PHE VAL PRO THR GLY LYS TYR          
SEQRES   7 T  181  HIS LEU GLN VAL CYS ALA THR LEU SER CYS LYS LEU ALA          
SEQRES   8 T  181  GLY ALA GLU GLU LEU TRP ASP TYR LEU THR GLU THR LEU          
SEQRES   9 T  181  GLY ILE GLY PRO GLY GLU VAL THR PRO ASP GLY LEU PHE          
SEQRES  10 T  181  SER VAL GLN LYS VAL GLU CYS LEU GLY SER CYS HIS THR          
SEQRES  11 T  181  ALA PRO VAL ILE GLN VAL ASN ASP GLU PRO TYR VAL GLU          
SEQRES  12 T  181  CYS VAL THR ARG ALA ARG LEU GLU ALA LEU LEU ALA GLY          
SEQRES  13 T  181  LEU ARG ALA GLY LYS ARG LEU GLU GLU ILE GLU LEU PRO          
SEQRES  14 T  181  GLY LYS CYS GLY HIS HIS VAL HIS GLU VAL GLU VAL              
SEQRES   1 U  783  MET VAL ARG VAL LYS VAL ASN ASP ARG ILE VAL GLU VAL          
SEQRES   2 U  783  PRO PRO GLY THR SER VAL MET ASP ALA VAL PHE HIS ALA          
SEQRES   3 U  783  GLY TYR ASP VAL PRO LEU PHE CYS SER GLU LYS HIS LEU          
SEQRES   4 U  783  SER PRO ILE GLY ALA CYS ARG MET CYS LEU VAL ARG ILE          
SEQRES   5 U  783  GLY LEU PRO LYS LYS GLY PRO ASP GLY LYS PRO LEU LEU          
SEQRES   6 U  783  ASN GLU LYS GLY GLU PRO GLU ILE GLN TRP GLN PRO LYS          
SEQRES   7 U  783  LEU ALA ALA SER CYS VAL THR ALA VAL ALA ASP GLY MET          
SEQRES   8 U  783  VAL VAL ASP THR LEU SER ASP VAL VAL ARG GLU ALA GLN          
SEQRES   9 U  783  ALA GLY MET VAL GLU PHE THR LEU LEU ASN HIS PRO LEU          
SEQRES  10 U  783  ASP CYS PRO THR CYS ASP LYS GLY GLY ALA CYS GLU LEU          
SEQRES  11 U  783  GLN ASP ARG THR VAL GLU TYR GLY LEU TYR GLU LYS TYR          
SEQRES  12 U  783  TYR GLN LYS GLY PRO LEU GLU LEU PRO VAL TYR THR ARG          
SEQRES  13 U  783  PHE GLU PHE THR ARG ARG HIS VAL ASP LYS HIS HIS PRO          
SEQRES  14 U  783  LEU SER PRO PHE VAL ILE LEU ASP ARG GLU ARG CYS ILE          
SEQRES  15 U  783  HIS CYS LYS ARG CYS VAL ARG TYR PHE GLU GLU VAL PRO          
SEQRES  16 U  783  GLY ASP GLU VAL LEU ASP PHE ILE GLU ARG GLY VAL HIS          
SEQRES  17 U  783  THR PHE ILE GLY THR MET ASP PHE GLY LEU PRO SER GLY          
SEQRES  18 U  783  PHE SER GLY ASN ILE THR ASP ILE CYS PRO VAL GLY ALA          
SEQRES  19 U  783  LEU LEU ASP LEU THR ALA ARG PHE ARG ALA ARG ASN TRP          
SEQRES  20 U  783  GLU MET GLU GLU THR PRO THR THR CYS ALA LEU CYS PRO          
SEQRES  21 U  783  VAL GLY CYS GLY ILE THR ALA ASP THR ARG SER GLY GLU          
SEQRES  22 U  783  LEU LEU ARG ILE ARG ALA ARG GLU VAL PRO GLU VAL ASN          
SEQRES  23 U  783  GLU ILE TRP ILE CYS ASP ALA GLY ARG PHE GLY HIS GLU          
SEQRES  24 U  783  TRP ALA ASP GLN ASN ARG LEU LYS THR PRO LEU VAL ARG          
SEQRES  25 U  783  LYS GLU GLY ARG LEU VAL GLU ALA THR TRP GLU GLU ALA          
SEQRES  26 U  783  PHE LEU ALA LEU LYS GLU GLY LEU LYS GLU ALA ARG GLY          
SEQRES  27 U  783  GLU GLU VAL GLY LEU TYR LEU ALA HIS ASP ALA THR LEU          
SEQRES  28 U  783  GLU GLU GLY LEU LEU ALA SER GLU LEU ALA LYS ALA LEU          
SEQRES  29 U  783  LYS THR PRO HIS LEU ASP PHE GLN GLY ARG THR ALA ALA          
SEQRES  30 U  783  PRO ALA SER LEU PHE PRO PRO ALA SER LEU GLU ASP LEU          
SEQRES  31 U  783  LEU GLN ALA ASP PHE ALA LEU VAL LEU GLY ASP PRO THR          
SEQRES  32 U  783  GLU GLU ALA PRO ILE LEU HIS LEU ARG LEU SER GLU PHE          
SEQRES  33 U  783  VAL ARG ASP LEU LYS PRO PRO HIS ARG TYR ASN HIS GLY          
SEQRES  34 U  783  THR PRO PHE ALA ASP LEU GLN ILE LYS GLU ARG MET PRO          
SEQRES  35 U  783  ARG ARG THR ASP LYS MET ALA LEU PHE ALA PRO TYR ARG          
SEQRES  36 U  783  ALA PRO LEU MET LYS TRP ALA ALA ILE HIS GLU VAL HIS          
SEQRES  37 U  783  ARG PRO GLY GLU GLU ARG GLU ILE LEU LEU ALA LEU LEU          
SEQRES  38 U  783  GLY ASP LYS GLU GLY SER GLU MET VAL ALA LYS ALA LYS          
SEQRES  39 U  783  GLU ALA TRP GLU LYS ALA LYS ASN PRO VAL LEU ILE LEU          
SEQRES  40 U  783  GLY ALA GLY VAL LEU GLN ASP THR VAL ALA ALA GLU ARG          
SEQRES  41 U  783  ALA ARG LEU LEU ALA GLU ARG LYS GLY ALA LYS VAL LEU          
SEQRES  42 U  783  ALA MET THR PRO ALA ALA ASN ALA ARG GLY LEU GLU ALA          
SEQRES  43 U  783  MET GLY VAL LEU PRO GLY ALA LYS GLY ALA SER TRP ASP          
SEQRES  44 U  783  GLU PRO GLY ALA LEU TYR ALA TYR TYR GLY PHE VAL PRO          
SEQRES  45 U  783  PRO GLU GLU ALA LEU LYS GLY LYS ARG PHE VAL VAL MET          
SEQRES  46 U  783  HIS LEU SER HIS LEU HIS PRO LEU ALA GLU ARG TYR ALA          
SEQRES  47 U  783  HIS VAL VAL LEU PRO ALA PRO THR PHE TYR GLU LYS ARG          
SEQRES  48 U  783  GLY HIS LEU VAL ASN LEU GLU GLY ARG VAL LEU PRO LEU          
SEQRES  49 U  783  SER PRO ALA PRO ILE GLU ASN GLY GLU ALA GLU GLY ALA          
SEQRES  50 U  783  LEU GLN VAL LEU ALA LEU LEU ALA GLU ALA LEU GLY VAL          
SEQRES  51 U  783  ARG PRO PRO PHE ARG LEU HIS LEU GLU ALA GLN LYS ALA          
SEQRES  52 U  783  LEU LYS ALA ARG LYS VAL PRO GLU ALA MET GLY ARG LEU          
SEQRES  53 U  783  SER PHE ARG LEU LYS GLU LEU ARG PRO LYS GLU ARG LYS          
SEQRES  54 U  783  GLY ALA PHE TYR LEU ARG PRO THR MET TRP LYS ALA HIS          
SEQRES  55 U  783  GLN ALA VAL GLY LYS ALA GLN GLU ALA ALA ARG ALA GLU          
SEQRES  56 U  783  LEU TRP ALA HIS PRO GLU THR ALA ARG ALA GLU ALA LEU          
SEQRES  57 U  783  PRO GLU GLY ALA GLN VAL ALA VAL GLU THR PRO PHE GLY          
SEQRES  58 U  783  ARG VAL GLU ALA ARG VAL VAL HIS ARG GLU ASP VAL PRO          
SEQRES  59 U  783  LYS GLY HIS LEU TYR LEU SER ALA LEU GLY PRO ALA ALA          
SEQRES  60 U  783  GLY LEU ARG VAL GLU GLY ARG VAL LEU VAL PRO ALA GLY          
SEQRES  61 U  783  GLY GLU ALA                                                  
SEQRES   1 V  409  MET ARG GLU GLU PHE LEU GLU GLU ILE PRO LEU ASP ALA          
SEQRES   2 V  409  PRO PRO GLU GLU ALA LYS GLU LEU ARG THR GLU VAL MET          
SEQRES   3 V  409  THR LEU ASN VAL GLY PRO GLN HIS PRO SER THR HIS GLY          
SEQRES   4 V  409  VAL LEU ARG LEU MET VAL THR LEU SER GLY GLU GLU VAL          
SEQRES   5 V  409  LEU GLU VAL VAL PRO HIS ILE GLY TYR LEU HIS THR GLY          
SEQRES   6 V  409  PHE GLU LYS THR MET GLU HIS ARG THR TYR LEU GLN ASN          
SEQRES   7 V  409  ILE THR TYR THR PRO ARG MET ASP TYR LEU HIS SER PHE          
SEQRES   8 V  409  ALA HIS ASP LEU ALA TYR ALA LEU ALA VAL GLU LYS LEU          
SEQRES   9 V  409  LEU GLY ALA VAL VAL PRO PRO ARG ALA GLU THR ILE ARG          
SEQRES  10 V  409  VAL ILE LEU ASN GLU LEU SER ARG LEU ALA SER HIS LEU          
SEQRES  11 V  409  VAL PHE LEU GLY THR GLY LEU LEU ASP LEU GLY ALA LEU          
SEQRES  12 V  409  THR PRO PHE PHE TYR ALA PHE ARG GLU ARG GLU THR ILE          
SEQRES  13 V  409  LEU ASP LEU PHE GLU TRP VAL THR GLY GLN ARG PHE HIS          
SEQRES  14 V  409  HIS ASN TYR ILE ARG ILE GLY GLY VAL LYS GLU ASP LEU          
SEQRES  15 V  409  PRO GLU GLU PHE VAL PRO GLU LEU LYS LYS LEU LEU GLU          
SEQRES  16 V  409  VAL LEU PRO HIS ARG ILE ASP GLU TYR GLU ALA LEU PHE          
SEQRES  17 V  409  ALA GLU SER PRO ILE PHE TYR GLU ARG ALA ARG GLY VAL          
SEQRES  18 V  409  GLY VAL ILE PRO PRO GLU VAL ALA ILE ASP LEU GLY LEU          
SEQRES  19 V  409  THR GLY GLY SER LEU ARG ALA SER GLY VAL ASN TYR ASP          
SEQRES  20 V  409  VAL ARG LYS ALA TYR PRO TYR SER GLY TYR GLU THR TYR          
SEQRES  21 V  409  THR PHE ASP VAL PRO LEU GLY GLU ARG GLY ASP VAL PHE          
SEQRES  22 V  409  ASP ARG MET LEU VAL ARG ILE ARG GLU MET ARG GLU SER          
SEQRES  23 V  409  VAL LYS ILE ILE LYS GLN ALA LEU GLU ARG LEU GLU PRO          
SEQRES  24 V  409  GLY PRO VAL ARG ASP PRO ASN PRO GLN ILE THR PRO PRO          
SEQRES  25 V  409  PRO ARG HIS LEU LEU GLU THR SER MET GLU ALA VAL ILE          
SEQRES  26 V  409  TYR HIS PHE LYS HIS TYR THR GLU GLY PHE HIS PRO PRO          
SEQRES  27 V  409  LYS GLY GLU VAL TYR VAL PRO THR GLU SER ALA ARG GLY          
SEQRES  28 V  409  GLU LEU GLY TYR TYR ILE VAL SER ASP GLY GLY SER MET          
SEQRES  29 V  409  PRO TYR ARG VAL LYS VAL ARG ALA PRO SER PHE VAL ASN          
SEQRES  30 V  409  LEU GLN SER LEU PRO TYR ALA CYS LYS GLY GLU GLN VAL          
SEQRES  31 V  409  PRO ASP MET VAL ALA ILE ILE ALA SER LEU ASP PRO VAL          
SEQRES  32 V  409  MET GLY ASP VAL ASP ARG                                      
SEQRES   1 W  207  MET ARG LEU GLU ARG VAL LEU GLU GLU ALA ARG ALA LYS          
SEQRES   2 W  207  GLY TYR PRO ILE GLU ASP ASN GLY LEU GLY ASN LEU TRP          
SEQRES   3 W  207  VAL VAL LEU PRO ARG GLU ARG PHE LYS GLU GLU MET ALA          
SEQRES   4 W  207  HIS TYR LYS ALA MET GLY PHE ASN PHE LEU ALA ASP ILE          
SEQRES   5 W  207  VAL GLY LEU ASP TYR LEU THR TYR PRO ASP PRO ARG PRO          
SEQRES   6 W  207  GLU ARG PHE ALA VAL VAL TYR GLU LEU VAL SER LEU PRO          
SEQRES   7 W  207  GLY TRP LYS ASP GLY ASP GLY SER ARG PHE PHE VAL ARG          
SEQRES   8 W  207  VAL TYR VAL PRO GLU GLU ASP PRO ARG LEU PRO THR VAL          
SEQRES   9 W  207  THR ASP LEU TRP GLY SER ALA ASN PHE LEU GLU ARG GLU          
SEQRES  10 W  207  VAL TYR ASP LEU PHE GLY ILE VAL PHE GLU GLY HIS PRO          
SEQRES  11 W  207  ASP LEU ARG LYS ILE LEU THR PRO GLU ASP LEU GLU GLY          
SEQRES  12 W  207  HIS PRO LEU ARG LYS ASP TYR PRO LEU GLY GLU THR PRO          
SEQRES  13 W  207  THR LEU PHE ARG GLU GLY ARG TYR ILE ILE PRO ALA GLU          
SEQRES  14 W  207  PHE ARG ALA ALA LEU THR GLY LYS ASP PRO GLY LEU THR          
SEQRES  15 W  207  PHE TYR LYS GLY GLY SER ARG LYS GLY TYR ARG SER LEU          
SEQRES  16 W  207  TRP ALA ASP LEU LYS LYS ALA ARG GLU VAL LYS GLY              
SEQRES   1 X  181  MET ALA LEU LYS ASP LEU PHE GLU ARG ASP VAL GLN GLU          
SEQRES   2 X  181  LEU GLU ARG GLU GLY ILE LEU PHE THR THR LEU GLU LYS          
SEQRES   3 X  181  LEU VAL ALA TRP GLY ARG SER ASN SER LEU TRP PRO ALA          
SEQRES   4 X  181  THR PHE GLY LEU ALA CYS CYS ALA ILE GLU MET MET ALA          
SEQRES   5 X  181  SER THR ASP ALA ARG ASN ASP LEU ALA ARG PHE GLY SER          
SEQRES   6 X  181  GLU VAL PHE ARG ALA SER PRO ARG GLN ALA ASP VAL MET          
SEQRES   7 X  181  ILE VAL ALA GLY ARG LEU SER LYS LYS MET ALA PRO VAL          
SEQRES   8 X  181  MET ARG ARG VAL TRP GLU GLN MET PRO ASP PRO LYS TRP          
SEQRES   9 X  181  VAL ILE SER MET GLY ALA CYS ALA SER SER GLY GLY MET          
SEQRES  10 X  181  PHE ASN ASN TYR ALA ILE VAL GLN ASN VAL ASP SER VAL          
SEQRES  11 X  181  VAL PRO VAL ASP VAL TYR VAL PRO GLY CYS PRO PRO ARG          
SEQRES  12 X  181  PRO GLU ALA LEU ILE TYR ALA VAL MET GLN LEU GLN LYS          
SEQRES  13 X  181  LYS VAL ARG GLY GLN ALA TYR ASN GLU ARG GLY GLU ARG          
SEQRES  14 X  181  LEU PRO PRO VAL ALA ALA TRP LYS ARG THR ARG GLY              
SEQRES   1 Y  182  MET THR LEU LYS ALA LEU ALA GLN SER LEU GLY ILE THR          
SEQRES   2 Y  182  LEU LYS TYR LEU PHE SER LYS PRO VAL THR VAL PRO TYR          
SEQRES   3 Y  182  PRO ASP ALA PRO VAL ALA LEU LYS PRO ARG PHE HIS GLY          
SEQRES   4 Y  182  ARG HIS VAL LEU THR ARG HIS PRO ASN GLY LEU GLU LYS          
SEQRES   5 Y  182  CYS ILE GLY CYS SER LEU CYS ALA ALA ALA CYS PRO ALA          
SEQRES   6 Y  182  TYR ALA ILE TYR VAL GLU PRO ALA GLU ASN ASP PRO GLU          
SEQRES   7 Y  182  ASN PRO VAL SER ALA GLY GLU ARG TYR ALA LYS VAL TYR          
SEQRES   8 Y  182  GLU ILE ASN MET LEU ARG CYS ILE PHE CYS GLY LEU CYS          
SEQRES   9 Y  182  GLU GLU ALA CYS PRO THR GLY ALA ILE VAL LEU GLY TYR          
SEQRES  10 Y  182  ASP PHE GLU MET ALA ASP TYR GLU TYR SER ASP LEU VAL          
SEQRES  11 Y  182  TYR GLY LYS GLU ASP MET LEU VAL ASP VAL VAL GLY THR          
SEQRES  12 Y  182  LYS PRO GLN ARG ARG GLU ALA LYS ARG THR GLY LYS PRO          
SEQRES  13 Y  182  VAL LYS VAL GLY TYR VAL VAL PRO TYR VAL ARG PRO GLU          
SEQRES  14 Y  182  LEU GLU GLY PHE LYS ALA PRO THR GLU GLY GLY LYS ARG          
SEQRES   1 Z  129  MET SER ALA SER SER GLU ARG GLU LEU TYR GLU ALA TRP          
SEQRES   2 Z  129  VAL GLU LEU LEU SER TRP MET ARG GLU TYR ALA GLN ALA          
SEQRES   3 Z  129  LYS GLY VAL ARG PHE GLU LYS GLU ALA ASP PHE PRO ASP          
SEQRES   4 Z  129  PHE ILE TYR ARG MET GLU ARG PRO TYR ASP LEU PRO THR          
SEQRES   5 Z  129  THR ILE MET THR ALA SER LEU SER ASP GLY LEU GLY GLU          
SEQRES   6 Z  129  PRO PHE LEU LEU ALA ASP VAL SER PRO ARG HIS ALA LYS          
SEQRES   7 Z  129  LEU LYS ARG ILE GLY LEU ARG LEU PRO ARG ALA HIS ILE          
SEQRES   8 Z  129  HIS LEU HIS ALA HIS TYR GLU PRO GLY LYS GLY LEU VAL          
SEQRES   9 Z  129  THR GLY LYS ILE PRO LEU THR LYS GLU ARG PHE PHE ALA          
SEQRES  10 Z  129  LEU ALA ASP ARG ALA ARG GLU ALA LEU ALA PHE ALA              
HET    SF4  1 439       8                                                       
HET    FES  2 182       4                                                       
HET    SF4  3 784       8                                                       
HET    SF4  3 785       8                                                       
HET    SF4  3 786       8                                                       
HET    FES  3 787       4                                                       
HET    SF4  6 182       8                                                       
HET    SF4  9 183       8                                                       
HET    SF4  9 184       8                                                       
HET    FMN  7 500      31                                                       
HET    SF4  A 439       8                                                       
HET    FES  B 182       4                                                       
HET    SF4  C 784       8                                                       
HET    SF4  C 785       8                                                       
HET    SF4  C 786       8                                                       
HET    FES  C 787       4                                                       
HET    SF4  F 182       8                                                       
HET    SF4  G 183       8                                                       
HET    SF4  G 184       8                                                       
HET    FMN  H 500      31                                                       
HET    SF4  J 439       8                                                       
HET    FES  K 182       4                                                       
HET    SF4  L 784       8                                                       
HET    SF4  L 785       8                                                       
HET    SF4  L 786       8                                                       
HET    FES  L 787       4                                                       
HET    SF4  O 182       8                                                       
HET    SF4  P 183       8                                                       
HET    SF4  P 184       8                                                       
HET    FMN  Q 500      31                                                       
HET    SF4  S 439       8                                                       
HET    FES  T 182       4                                                       
HET    SF4  U 784       8                                                       
HET    SF4  U 785       8                                                       
HET    SF4  U 786       8                                                       
HET    FES  U 787       4                                                       
HET    SF4  X 182       8                                                       
HET    SF4  Y 183       8                                                       
HET    SF4  Y 184       8                                                       
HET    FMN  Z 500      31                                                       
HETNAM     SF4 IRON/SULFUR CLUSTER                                              
HETNAM     FES FE2/S2 (INORGANIC) CLUSTER                                       
HETNAM     FMN FLAVIN MONONUCLEOTIDE                                            
HETSYN     FMN RIBOFLAVIN MONOPHOSPHATE                                         
FORMUL  33  SF4    28(FE4 S4)                                                   
FORMUL  34  FES    8(FE2 S2)                                                    
FORMUL  42  FMN    4(C17 H21 N4 O9 P)                                           
HELIX    1   1 THR 1   28  ARG 1   34  1                                   7    
HELIX    2   2 HIS 1   35  GLY 1   37  5                                   3    
HELIX    3   3 TYR 1   38  LYS 1   48  1                                  11    
HELIX    4   4 THR 1   49  ARG 1   59  1                                  11    
HELIX    5   5 PRO 1   71  PHE 1   78  1                                   8    
HELIX    6   6 LYS 1  102  VAL 1  110  1                                   9    
HELIX    7   7 VAL 1  110  ILE 1  125  1                                  16    
HELIX    8   8 TYR 1  138  ARG 1  155  1                                  18    
HELIX    9   9 ALA 1  179  GLY 1  183  5                                   5    
HELIX   10  10 GLU 1  184  GLU 1  193  1                                  10    
HELIX   11  11 GLY 1  210  LYS 1  214  5                                   5    
HELIX   12  12 VAL 1  221  ARG 1  233  1                                  13    
HELIX   13  13 GLY 1  234  GLN 1  240  1                                   7    
HELIX   14  14 THR 1  271  TYR 1  277  1                                   7    
HELIX   15  15 THR 1  303  ASP 1  308  1                                   6    
HELIX   16  16 SER 1  336  SER 1  352  1                                  17    
HELIX   17  17 CYS 1  356  GLY 1  362  1                                   7    
HELIX   18  18 PHE 1  366  GLY 1  375  1                                  10    
HELIX   19  19 GLU 1  380  GLY 1  396  1                                  17    
HELIX   20  20 PRO 1  401  GLU 1  427  1                                  27    
HELIX   21  21 LYS 2    7  LYS 2   17  1                                  11    
HELIX   22  22 GLY 2   22  ALA 2   25  5                                   4    
HELIX   23  23 ALA 2   26  GLY 2   39  1                                  14    
HELIX   24  24 ARG 2   42  GLY 2   54  1                                  13    
HELIX   25  25 THR 2   56  TYR 2   67  1                                  12    
HELIX   26  26 THR 2   85  LEU 2   90  1                                   6    
HELIX   27  27 GLY 2   92  GLY 2  105  1                                  14    
HELIX   28  28 THR 2  146  ALA 2  159  1                                  14    
HELIX   29  29 ARG 2  162  ILE 2  166  5                                   5    
HELIX   30  30 SER 3   18  GLY 3   27  1                                  10    
HELIX   31  31 SER 3   97  ASN 3  114  1                                  18    
HELIX   32  32 LYS 3  124  ALA 3  127  5                                   4    
HELIX   33  33 CYS 3  128  TYR 3  137  1                                  10    
HELIX   34  34 LYS 3  185  VAL 3  194  1                                  10    
HELIX   35  35 ARG 3  205  THR 3  209  5                                   5    
HELIX   36  36 GLY 3  224  CYS 3  230  1                                   7    
HELIX   37  37 ASP 3  237  ARG 3  241  5                                   5    
HELIX   38  38 CYS 3  291  GLY 3  297  1                                   7    
HELIX   39  39 HIS 3  298  GLN 3  303  1                                   6    
HELIX   40  40 THR 3  321  LYS 3  334  1                                  14    
HELIX   41  41 THR 3  350  LEU 3  364  1                                  15    
HELIX   42  42 PRO 3  378  PHE 3  382  5                                   5    
HELIX   43  43 SER 3  386  ALA 3  393  1                                   8    
HELIX   44  44 ASP 3  401  ALA 3  406  1                                   6    
HELIX   45  45 ALA 3  406  VAL 3  417  1                                  12    
HELIX   46  46 ARG 3  444  ASP 3  446  5                                   3    
HELIX   47  47 ALA 3  456  LYS 3  460  5                                   5    
HELIX   48  48 GLU 3  472  GLY 3  482  1                                  11    
HELIX   49  49 SER 3  487  ALA 3  500  1                                  14    
HELIX   50  50 ALA 3  509  LEU 3  512  5                                   4    
HELIX   51  51 GLN 3  513  ARG 3  527  1                                  15    
HELIX   52  52 ASN 3  540  ALA 3  546  1                                   7    
HELIX   53  53 PRO 3  573  LYS 3  578  1                                   6    
HELIX   54  54 LEU 3  593  ALA 3  598  1                                   6    
HELIX   55  55 THR 3  606  LYS 3  610  5                                   5    
HELIX   56  56 GLY 3  636  GLY 3  649  1                                  14    
HELIX   57  57 LEU 3  656  ARG 3  667  1                                  12    
HELIX   58  58 LYS 3  700  ALA 3  704  5                                   5    
HELIX   59  59 ALA 3  708  ARG 3  713  1                                   6    
HELIX   60  60 GLY 4   65  MET 4   70  1                                   6    
HELIX   61  61 GLU 4   71  ARG 4   73  5                                   3    
HELIX   62  62 THR 4   74  THR 4   82  1                                   9    
HELIX   63  63 PRO 4   83  MET 4   85  5                                   3    
HELIX   64  64 HIS 4   89  LEU 4  105  1                                  17    
HELIX   65  65 PRO 4  110  GLY 4  141  1                                  32    
HELIX   66  66 ALA 4  142  THR 4  164  1                                  23    
HELIX   67  67 GLU 4  185  LEU 4  194  1                                  10    
HELIX   68  68 ILE 4  201  ALA 4  209  1                                   9    
HELIX   69  69 VAL 4  272  ARG 4  296  1                                  25    
HELIX   70  70 GLU 4  322  GLU 4  333  1                                  12    
HELIX   71  71 PRO 4  373  LEU 4  378  1                                   6    
HELIX   72  72 SER 4  380  CYS 4  385  1                                   6    
HELIX   73  73 GLN 4  389  MET 4  393  5                                   5    
HELIX   74  74 VAL 4  394  SER 4  399  1                                   6    
HELIX   75  75 VAL 4  403  ARG 4  409  1                                   7    
HELIX   76  76 MET 5    1  ALA 5   12  1                                  12    
HELIX   77  77 ARG 5   33  TYR 5   41  1                                   9    
HELIX   78  78 LEU 5  114  VAL 5  125  1                                  12    
HELIX   79  79 ILE 5  166  ARG 5  171  1                                   6    
HELIX   80  80 GLY 6   18  SER 6   35  1                                  18    
HELIX   81  81 ALA 6   44  MET 6   50  1                                   7    
HELIX   82  82 MET 6   51  THR 6   54  5                                   4    
HELIX   83  83 MET 6   88  GLN 6   98  1                                  11    
HELIX   84  84 GLY 6  109  SER 6  114  1                                   6    
HELIX   85  85 ASN 6  126  VAL 6  130  5                                   5    
HELIX   86  86 ARG 6  143  GLY 6  160  1                                  18    
HELIX   87  87 SER 9   57  CYS 9   63  1                                   7    
HELIX   88  88 GLY 9  102  CYS 9  108  1                                   7    
HELIX   89  89 GLU 9  125  ASP 9  128  5                                   4    
HELIX   90  90 THR 9  143  GLY 9  154  1                                  12    
HELIX   91  91 ALA 7    3  GLY 7   28  1                                  26    
HELIX   92  92 PHE 7   37  TYR 7   42  1                                   6    
HELIX   93  93 THR 7  111  ALA 7  127  1                                  17    
HELIX   94  94 THR A   28  ARG A   34  1                                   7    
HELIX   95  95 HIS A   35  GLY A   37  5                                   3    
HELIX   96  96 TYR A   38  LYS A   48  1                                  11    
HELIX   97  97 THR A   49  ARG A   59  1                                  11    
HELIX   98  98 PRO A   71  PHE A   78  1                                   8    
HELIX   99  99 LYS A  102  VAL A  110  1                                   9    
HELIX  100 100 VAL A  110  ILE A  125  1                                  16    
HELIX  101 101 TYR A  138  ARG A  155  1                                  18    
HELIX  102 102 ALA A  179  GLY A  183  5                                   5    
HELIX  103 103 GLU A  184  GLU A  193  1                                  10    
HELIX  104 104 GLY A  210  LYS A  214  5                                   5    
HELIX  105 105 VAL A  221  ARG A  233  1                                  13    
HELIX  106 106 GLY A  234  GLN A  240  1                                   7    
HELIX  107 107 THR A  271  TYR A  277  1                                   7    
HELIX  108 108 THR A  303  ASP A  308  1                                   6    
HELIX  109 109 SER A  336  SER A  352  1                                  17    
HELIX  110 110 CYS A  356  GLU A  361  1                                   6    
HELIX  111 111 GLY A  365  GLY A  375  1                                  11    
HELIX  112 112 GLU A  380  GLY A  396  1                                  17    
HELIX  113 113 PRO A  401  GLU A  427  1                                  27    
HELIX  114 114 LYS B    7  LYS B   17  1                                  11    
HELIX  115 115 GLY B   22  ALA B   25  5                                   4    
HELIX  116 116 ALA B   26  GLY B   39  1                                  14    
HELIX  117 117 ARG B   42  GLY B   54  1                                  13    
HELIX  118 118 THR B   56  TYR B   67  1                                  12    
HELIX  119 119 THR B   85  LEU B   90  1                                   6    
HELIX  120 120 GLY B   92  GLY B  105  1                                  14    
HELIX  121 121 THR B  146  ALA B  159  1                                  14    
HELIX  122 122 ARG B  162  ILE B  166  5                                   5    
HELIX  123 123 SER C   18  GLY C   27  1                                  10    
HELIX  124 124 SER C   97  ASN C  114  1                                  18    
HELIX  125 125 LYS C  124  ALA C  127  5                                   4    
HELIX  126 126 CYS C  128  TYR C  137  1                                  10    
HELIX  127 127 LYS C  185  VAL C  194  1                                  10    
HELIX  128 128 ARG C  205  THR C  209  5                                   5    
HELIX  129 129 GLY C  224  CYS C  230  1                                   7    
HELIX  130 130 ASP C  237  ARG C  241  5                                   5    
HELIX  131 131 CYS C  291  GLY C  297  1                                   7    
HELIX  132 132 HIS C  298  GLN C  303  1                                   6    
HELIX  133 133 THR C  321  LYS C  334  1                                  14    
HELIX  134 134 THR C  350  LEU C  364  1                                  15    
HELIX  135 135 SER C  386  ALA C  393  1                                   8    
HELIX  136 136 ASP C  401  ALA C  406  1                                   6    
HELIX  137 137 ALA C  406  VAL C  417  1                                  12    
HELIX  138 138 ARG C  444  ASP C  446  5                                   3    
HELIX  139 139 ALA C  456  LYS C  460  5                                   5    
HELIX  140 140 GLU C  472  GLY C  482  1                                  11    
HELIX  141 141 SER C  487  ALA C  500  1                                  14    
HELIX  142 142 ALA C  509  LEU C  512  5                                   4    
HELIX  143 143 GLN C  513  ARG C  527  1                                  15    
HELIX  144 144 ASN C  540  ALA C  546  1                                   7    
HELIX  145 145 PRO C  573  LYS C  578  1                                   6    
HELIX  146 146 LEU C  593  ALA C  598  1                                   6    
HELIX  147 147 THR C  606  LYS C  610  5                                   5    
HELIX  148 148 GLY C  636  GLY C  649  1                                  14    
HELIX  149 149 LEU C  656  ARG C  667  1                                  12    
HELIX  150 150 LYS C  700  ALA C  704  5                                   5    
HELIX  151 151 ALA C  708  ARG C  713  1                                   6    
HELIX  152 152 GLY D   65  MET D   70  1                                   6    
HELIX  153 153 GLU D   71  ARG D   73  5                                   3    
HELIX  154 154 THR D   74  THR D   82  1                                   9    
HELIX  155 155 PRO D   83  MET D   85  5                                   3    
HELIX  156 156 HIS D   89  LEU D  105  1                                  17    
HELIX  157 157 PRO D  110  GLY D  141  1                                  32    
HELIX  158 158 ALA D  142  THR D  164  1                                  23    
HELIX  159 159 GLU D  185  LEU D  197  1                                  13    
HELIX  160 160 ILE D  201  ALA D  209  1                                   9    
HELIX  161 161 VAL D  272  ARG D  296  1                                  25    
HELIX  162 162 GLU D  322  GLU D  333  1                                  12    
HELIX  163 163 ALA D  372  LEU D  378  1                                   7    
HELIX  164 164 SER D  380  CYS D  385  1                                   6    
HELIX  165 165 GLN D  389  MET D  393  5                                   5    
HELIX  166 166 VAL D  394  SER D  399  1                                   6    
HELIX  167 167 VAL D  403  ARG D  409  1                                   7    
HELIX  168 168 MET E    1  ALA E   12  1                                  12    
HELIX  169 169 ARG E   33  TYR E   41  1                                   9    
HELIX  170 170 LEU E  114  VAL E  125  1                                  12    
HELIX  171 171 ILE E  166  ARG E  171  1                                   6    
HELIX  172 172 GLY F   18  SER F   35  1                                  18    
HELIX  173 173 CYS F   45  MET F   50  1                                   6    
HELIX  174 174 MET F   51  THR F   54  5                                   4    
HELIX  175 175 MET F   88  GLN F   98  1                                  11    
HELIX  176 176 GLY F  109  SER F  114  1                                   6    
HELIX  177 177 ASN F  126  VAL F  130  5                                   5    
HELIX  178 178 ARG F  143  ARG F  159  1                                  17    
HELIX  179 179 SER G   57  CYS G   63  1                                   7    
HELIX  180 180 GLY G  102  CYS G  108  1                                   7    
HELIX  181 181 GLU G  125  ASP G  128  5                                   4    
HELIX  182 182 THR G  143  GLY G  154  1                                  12    
HELIX  183 183 ALA H    3  GLY H   28  1                                  26    
HELIX  184 184 PHE H   37  TYR H   42  1                                   6    
HELIX  185 185 THR H  111  ALA H  127  1                                  17    
HELIX  186 186 THR J   28  ARG J   34  1                                   7    
HELIX  187 187 HIS J   35  GLY J   37  5                                   3    
HELIX  188 188 TYR J   38  LYS J   48  1                                  11    
HELIX  189 189 THR J   49  ARG J   59  1                                  11    
HELIX  190 190 PRO J   71  PHE J   78  1                                   8    
HELIX  191 191 LYS J  102  VAL J  110  1                                   9    
HELIX  192 192 VAL J  110  ILE J  125  1                                  16    
HELIX  193 193 TYR J  138  ARG J  155  1                                  18    
HELIX  194 194 ALA J  179  GLY J  183  5                                   5    
HELIX  195 195 GLU J  184  GLU J  193  1                                  10    
HELIX  196 196 GLY J  210  LYS J  214  5                                   5    
HELIX  197 197 VAL J  221  ARG J  233  1                                  13    
HELIX  198 198 GLY J  234  GLN J  240  1                                   7    
HELIX  199 199 THR J  271  TYR J  277  1                                   7    
HELIX  200 200 THR J  303  ASP J  308  1                                   6    
HELIX  201 201 SER J  336  SER J  352  1                                  17    
HELIX  202 202 CYS J  356  GLY J  365  1                                  10    
HELIX  203 203 GLY J  365  GLY J  375  1                                  11    
HELIX  204 204 GLU J  380  GLY J  396  1                                  17    
HELIX  205 205 PRO J  401  GLU J  427  1                                  27    
HELIX  206 206 LYS K    7  LYS K   17  1                                  11    
HELIX  207 207 GLY K   22  ALA K   25  5                                   4    
HELIX  208 208 ALA K   26  GLY K   39  1                                  14    
HELIX  209 209 ARG K   42  GLY K   54  1                                  13    
HELIX  210 210 THR K   56  TYR K   67  1                                  12    
HELIX  211 211 THR K   85  LEU K   90  1                                   6    
HELIX  212 212 GLY K   92  GLY K  105  1                                  14    
HELIX  213 213 THR K  146  ALA K  159  1                                  14    
HELIX  214 214 ARG K  162  ILE K  166  5                                   5    
HELIX  215 215 SER L   18  GLY L   27  1                                  10    
HELIX  216 216 SER L   97  ASN L  114  1                                  18    
HELIX  217 217 LYS L  124  ALA L  127  5                                   4    
HELIX  218 218 CYS L  128  TYR L  137  1                                  10    
HELIX  219 219 LYS L  185  VAL L  194  1                                  10    
HELIX  220 220 ARG L  205  THR L  209  5                                   5    
HELIX  221 221 GLY L  224  CYS L  230  1                                   7    
HELIX  222 222 ASP L  237  ARG L  241  5                                   5    
HELIX  223 223 CYS L  291  GLY L  297  1                                   7    
HELIX  224 224 HIS L  298  GLN L  303  1                                   6    
HELIX  225 225 THR L  321  LYS L  334  1                                  14    
HELIX  226 226 THR L  350  LEU L  364  1                                  15    
HELIX  227 227 PRO L  378  PHE L  382  5                                   5    
HELIX  228 228 SER L  386  ALA L  393  1                                   8    
HELIX  229 229 ASP L  401  ALA L  406  1                                   6    
HELIX  230 230 ALA L  406  VAL L  417  1                                  12    
HELIX  231 231 ALA L  456  LYS L  460  5                                   5    
HELIX  232 232 GLU L  472  GLY L  482  1                                  11    
HELIX  233 233 SER L  487  ALA L  500  1                                  14    
HELIX  234 234 ALA L  509  LEU L  512  5                                   4    
HELIX  235 235 GLN L  513  ARG L  527  1                                  15    
HELIX  236 236 ASN L  540  GLY L  548  1                                   9    
HELIX  237 237 PRO L  573  LYS L  578  1                                   6    
HELIX  238 238 LEU L  593  ALA L  598  1                                   6    
HELIX  239 239 THR L  606  LYS L  610  5                                   5    
HELIX  240 240 GLY L  636  GLY L  649  1                                  14    
HELIX  241 241 LEU L  656  ARG L  667  1                                  12    
HELIX  242 242 LYS L  700  ALA L  704  5                                   5    
HELIX  243 243 VAL L  705  LYS L  707  5                                   3    
HELIX  244 244 ALA L  708  ARG L  713  1                                   6    
HELIX  245 245 GLY M   65  MET M   70  1                                   6    
HELIX  246 246 GLU M   71  ARG M   73  5                                   3    
HELIX  247 247 THR M   74  THR M   82  1                                   9    
HELIX  248 248 PRO M   83  MET M   85  5                                   3    
HELIX  249 249 HIS M   89  LEU M  105  1                                  17    
HELIX  250 250 PRO M  110  GLY M  141  1                                  32    
HELIX  251 251 ALA M  142  THR M  164  1                                  23    
HELIX  252 252 GLU M  185  ILE M  201  1                                  17    
HELIX  253 253 ILE M  201  ALA M  209  1                                   9    
HELIX  254 254 VAL M  272  ARG M  296  1                                  25    
HELIX  255 255 GLU M  322  GLU M  333  1                                  12    
HELIX  256 256 PRO M  373  CYS M  385  1                                  13    
HELIX  257 257 GLN M  389  MET M  393  5                                   5    
HELIX  258 258 VAL M  394  SER M  399  1                                   6    
HELIX  259 259 VAL M  403  ASP M  408  1                                   6    
HELIX  260 260 MET N    1  ALA N   12  1                                  12    
HELIX  261 261 ARG N   33  TYR N   41  1                                   9    
HELIX  262 262 LEU N  114  VAL N  125  1                                  12    
HELIX  263 263 ILE N  166  ARG N  171  1                                   6    
HELIX  264 264 GLY O   18  SER O   33  1                                  16    
HELIX  265 265 ALA O   44  MET O   50  1                                   7    
HELIX  266 266 MET O   51  THR O   54  5                                   4    
HELIX  267 267 MET O   88  GLN O   98  1                                  11    
HELIX  268 268 GLY O  109  SER O  114  1                                   6    
HELIX  269 269 ASN O  126  VAL O  130  5                                   5    
HELIX  270 270 ARG O  143  GLY O  160  1                                  18    
HELIX  271 271 SER P   57  CYS P   63  1                                   7    
HELIX  272 272 GLY P  102  CYS P  108  1                                   7    
HELIX  273 273 GLU P  125  ASP P  128  5                                   4    
HELIX  274 274 THR P  143  GLY P  154  1                                  12    
HELIX  275 275 ALA Q    3  GLY Q   28  1                                  26    
HELIX  276 276 PHE Q   37  TYR Q   42  1                                   6    
HELIX  277 277 THR Q  111  ALA Q  127  1                                  17    
HELIX  278 278 THR S   28  ARG S   34  1                                   7    
HELIX  279 279 HIS S   35  GLY S   37  5                                   3    
HELIX  280 280 TYR S   38  LYS S   48  1                                  11    
HELIX  281 281 THR S   49  ARG S   59  1                                  11    
HELIX  282 282 PRO S   71  PHE S   78  1                                   8    
HELIX  283 283 LYS S  102  VAL S  110  1                                   9    
HELIX  284 284 VAL S  110  ILE S  125  1                                  16    
HELIX  285 285 TYR S  138  ARG S  155  1                                  18    
HELIX  286 286 ALA S  179  GLY S  183  5                                   5    
HELIX  287 287 GLU S  184  GLU S  193  1                                  10    
HELIX  288 288 GLY S  210  LYS S  214  5                                   5    
HELIX  289 289 VAL S  221  ARG S  233  1                                  13    
HELIX  290 290 GLY S  234  GLN S  240  1                                   7    
HELIX  291 291 THR S  271  TYR S  277  1                                   7    
HELIX  292 292 THR S  303  ASP S  308  1                                   6    
HELIX  293 293 SER S  336  SER S  352  1                                  17    
HELIX  294 294 CYS S  356  GLY S  362  1                                   7    
HELIX  295 295 GLY S  365  GLY S  375  1                                  11    
HELIX  296 296 GLU S  380  GLY S  396  1                                  17    
HELIX  297 297 PRO S  401  GLU S  427  1                                  27    
HELIX  298 298 LYS T    7  LYS T   17  1                                  11    
HELIX  299 299 GLY T   22  ALA T   25  5                                   4    
HELIX  300 300 ALA T   26  GLY T   39  1                                  14    
HELIX  301 301 ARG T   42  GLY T   54  1                                  13    
HELIX  302 302 THR T   56  TYR T   67  1                                  12    
HELIX  303 303 THR T   85  LEU T   90  1                                   6    
HELIX  304 304 GLY T   92  GLY T  105  1                                  14    
HELIX  305 305 THR T  146  ALA T  159  1                                  14    
HELIX  306 306 ARG T  162  ILE T  166  5                                   5    
HELIX  307 307 SER U   18  GLY U   27  1                                  10    
HELIX  308 308 SER U   97  ASN U  114  1                                  18    
HELIX  309 309 LYS U  124  ALA U  127  5                                   4    
HELIX  310 310 CYS U  128  TYR U  137  1                                  10    
HELIX  311 311 LYS U  185  VAL U  194  1                                  10    
HELIX  312 312 ARG U  205  THR U  209  5                                   5    
HELIX  313 313 GLY U  224  CYS U  230  1                                   7    
HELIX  314 314 ASP U  237  ARG U  241  5                                   5    
HELIX  315 315 CYS U  291  GLY U  297  1                                   7    
HELIX  316 316 HIS U  298  GLN U  303  1                                   6    
HELIX  317 317 THR U  321  LYS U  334  1                                  14    
HELIX  318 318 THR U  350  LEU U  364  1                                  15    
HELIX  319 319 PRO U  378  PHE U  382  5                                   5    
HELIX  320 320 SER U  386  ALA U  393  1                                   8    
HELIX  321 321 ASP U  401  ALA U  406  1                                   6    
HELIX  322 322 ALA U  406  VAL U  417  1                                  12    
HELIX  323 323 ALA U  456  LYS U  460  5                                   5    
HELIX  324 324 GLU U  472  GLY U  482  1                                  11    
HELIX  325 325 SER U  487  ALA U  500  1                                  14    
HELIX  326 326 ALA U  509  LEU U  512  5                                   4    
HELIX  327 327 GLN U  513  ARG U  527  1                                  15    
HELIX  328 328 ASN U  540  ALA U  546  1                                   7    
HELIX  329 329 PRO U  573  LYS U  578  1                                   6    
HELIX  330 330 LEU U  593  ALA U  598  1                                   6    
HELIX  331 331 THR U  606  LYS U  610  5                                   5    
HELIX  332 332 GLY U  636  GLY U  649  1                                  14    
HELIX  333 333 LEU U  656  ARG U  667  1                                  12    
HELIX  334 334 LYS U  700  ALA U  704  5                                   5    
HELIX  335 335 VAL U  705  LYS U  707  5                                   3    
HELIX  336 336 ALA U  708  ARG U  713  1                                   6    
HELIX  337 337 GLY V   65  MET V   70  1                                   6    
HELIX  338 338 GLU V   71  ARG V   73  5                                   3    
HELIX  339 339 THR V   74  THR V   82  1                                   9    
HELIX  340 340 PRO V   83  MET V   85  5                                   3    
HELIX  341 341 HIS V   89  LEU V  105  1                                  17    
HELIX  342 342 PRO V  110  GLY V  141  1                                  32    
HELIX  343 343 ALA V  142  THR V  164  1                                  23    
HELIX  344 344 GLU V  185  ILE V  201  1                                  17    
HELIX  345 345 ILE V  201  ALA V  209  1                                   9    
HELIX  346 346 VAL V  272  ARG V  296  1                                  25    
HELIX  347 347 GLU V  322  GLU V  333  1                                  12    
HELIX  348 348 PRO V  373  LEU V  378  1                                   6    
HELIX  349 349 SER V  380  CYS V  385  1                                   6    
HELIX  350 350 GLN V  389  MET V  393  5                                   5    
HELIX  351 351 VAL V  394  SER V  399  1                                   6    
HELIX  352 352 VAL V  403  ASP V  408  1                                   6    
HELIX  353 353 MET W    1  ALA W   12  1                                  12    
HELIX  354 354 ARG W   33  TYR W   41  1                                   9    
HELIX  355 355 LEU W  114  VAL W  125  1                                  12    
HELIX  356 356 ILE W  166  ARG W  171  1                                   6    
HELIX  357 357 GLY X   18  SER X   35  1                                  18    
HELIX  358 358 ALA X   44  MET X   50  1                                   7    
HELIX  359 359 MET X   51  THR X   54  5                                   4    
HELIX  360 360 MET X   88  GLN X   98  1                                  11    
HELIX  361 361 GLY X  109  SER X  114  1                                   6    
HELIX  362 362 ASN X  126  VAL X  130  5                                   5    
HELIX  363 363 ARG X  143  ARG X  159  1                                  17    
HELIX  364 364 SER Y   57  CYS Y   63  1                                   7    
HELIX  365 365 GLY Y  102  CYS Y  108  1                                   7    
HELIX  366 366 GLU Y  125  ASP Y  128  5                                   4    
HELIX  367 367 THR Y  143  GLY Y  154  1                                  12    
HELIX  368 368 ALA Z    3  GLY Z   28  1                                  26    
HELIX  369 369 PHE Z   37  TYR Z   42  1                                   6    
HELIX  370 370 THR Z  111  ALA Z  127  1                                  17    
SHEET    1   A 4 ASP 1 170  ARG 1 175  0                                        
SHEET    2   A 4 VAL 1 129  VAL 1 134  1  N  ILE 1 132   O  HIS 1 172           
SHEET    3   A 4 TYR 1  88  ALA 1  93  1  N  CYS 1  91   O  TYR 1 131           
SHEET    4   A 4 THR 1 216  ASN 1 220  1  O  ASN 1 219   N  ASN 1  92           
SHEET    1   B 5 GLY 1 262  PRO 1 267  0                                        
SHEET    2   B 5 MET 1 249  SER 1 255 -1  N  TYR 1 252   O  TYR 1 264           
SHEET    3   B 5 GLY 1 327  PRO 1 332  1  O  VAL 1 328   N  GLN 1 253           
SHEET    4   B 5 ILE 1 287  ILE 1 291 -1  N  GLN 1 288   O  ILE 1 331           
SHEET    5   B 5 LEU 1 300  PRO 1 301 -1  O  LEU 1 300   N  ILE 1 290           
SHEET    1   C 3 PHE 2 117  VAL 2 122  0                                        
SHEET    2   C 3 TYR 2  78  CYS 2  83  1  N  VAL 2  82   O  VAL 2 122           
SHEET    3   C 3 ILE 2 134  GLN 2 135 -1  O  GLN 2 135   N  GLN 2  81           
SHEET    1   D 2 VAL 3   2  LYS 3   5  0                                        
SHEET    2   D 2 ILE 3  10  VAL 3  13 -1  O  VAL 3  11   N  VAL 3   4           
SHEET    1   E 3 ALA 3  80  ALA 3  81  0                                        
SHEET    2   E 3 LEU 3  49  GLY 3  53 -1  N  VAL 3  50   O  ALA 3  80           
SHEET    3   E 3 VAL 3  92  ASP 3  94 -1  O  ASP 3  94   N  ARG 3  51           
SHEET    1   F 2 HIS 3 168  PRO 3 169  0                                        
SHEET    2   F 2 LEU 3 176  ASP 3 177 -1  O  ASP 3 177   N  HIS 3 168           
SHEET    1   G 3 GLU 3 250  THR 3 254  0                                        
SHEET    2   G 3 ILE 3 265  ARG 3 270 -1  O  ALA 3 267   N  THR 3 252           
SHEET    3   G 3 GLU 3 273  ALA 3 279 -1  O  ARG 3 278   N  THR 3 266           
SHEET    1   H 2 LEU 3 310  ARG 3 312  0                                        
SHEET    2   H 2 LEU 3 317  GLU 3 319 -1  O  VAL 3 318   N  VAL 3 311           
SHEET    1   I 5 LEU 3 369  PHE 3 371  0                                        
SHEET    2   I 5 GLY 3 342  LEU 3 345  1  N  LEU 3 345   O  ASP 3 370           
SHEET    3   I 5 ALA 3 566  TYR 3 568  1  O  TYR 3 567   N  TYR 3 344           
SHEET    4   I 5 VAL 3 583  MET 3 585  1  O  VAL 3 584   N  TYR 3 568           
SHEET    5   I 5 VAL 3 600  VAL 3 601  1  O  VAL 3 600   N  MET 3 585           
SHEET    1   J 5 ILE 3 464  VAL 3 467  0                                        
SHEET    2   J 5 MET 3 448  ALA 3 452  1  N  LEU 3 450   O  GLU 3 466           
SHEET    3   J 5 ALA 3 396  LEU 3 399  1  N  VAL 3 398   O  ALA 3 449           
SHEET    4   J 5 VAL 3 504  LEU 3 507  1  O  ILE 3 506   N  LEU 3 397           
SHEET    5   J 5 LYS 3 531  ALA 3 534  1  O  LEU 3 533   N  LEU 3 505           
SHEET    1   K 2 GLY 3 612  VAL 3 615  0                                        
SHEET    2   K 2 VAL 3 621  LEU 3 624 -1  O  LEU 3 622   N  LEU 3 614           
SHEET    1   L 2 PHE 3 692  TYR 3 693  0                                        
SHEET    2   L 2 LEU 3 760  SER 3 761 -1  O  SER 3 761   N  PHE 3 692           
SHEET    1   M 2 GLN 3 733  THR 3 738  0                                        
SHEET    2   M 2 GLY 3 741  ARG 3 746 -1  O  GLY 3 741   N  THR 3 738           
SHEET    1   N 3 SER 4  36  HIS 4  38  0                                        
SHEET    2   N 3 MET 4  44  LEU 4  47 -1  O  VAL 4  45   N  THR 4  37           
SHEET    3   N 3 VAL 4  55  HIS 4  58 -1  O  VAL 4  56   N  THR 4  46           
SHEET    1   O 2 ILE 4 173  ARG 4 174  0                                        
SHEET    2   O 2 GLY 4 177  VAL 4 178 -1  O  GLY 4 177   N  ARG 4 174           
SHEET    1   P 2 TYR 4 355  VAL 4 358  0                                        
SHEET    2   P 2 ARG 4 367  VAL 4 370 -1  O  LYS 4 369   N  TYR 4 356           
SHEET    1   Q 5 ILE 5  17  ASP 5  19  0                                        
SHEET    2   Q 5 LEU 5  25  VAL 5  28 -1  O  TRP 5  26   N  GLU 5  18           
SHEET    3   Q 5 ARG 5  87  VAL 5  94  1  O  ARG 5  91   N  VAL 5  27           
SHEET    4   Q 5 PHE 5  68  VAL 5  75 -1  N  PHE 5  68   O  VAL 5  94           
SHEET    5   Q 5 ILE 5  52  ASP 5  56 -1  N  LEU 5  55   O  ALA 5  69           
SHEET    1   R 2 THR 5 157  LEU 5 158  0                                        
SHEET    2   R 2 TYR 5 164  ILE 5 165 -1  O  ILE 5 165   N  THR 5 157           
SHEET    1   S 4 PHE 6  41  GLY 6  42  0                                        
SHEET    2   S 4 MET 6  78  ALA 6  81  1  O  ILE 6  79   N  PHE 6  41           
SHEET    3   S 4 VAL 6 105  MET 6 108  1  O  MET 6 108   N  VAL 6  80           
SHEET    4   S 4 VAL 6 135  VAL 6 137  1  O  VAL 6 137   N  SER 6 107           
SHEET    1   T 2 VAL 9  31  ALA 9  32  0                                        
SHEET    2   T 2 TYR 9 161  VAL 9 162  1  O  VAL 9 162   N  VAL 9  31           
SHEET    1   U 2 HIS 9  41  LEU 9  43  0                                        
SHEET    2   U 2 ILE 9 113  LEU 9 115 -1  O  VAL 9 114   N  VAL 9  42           
SHEET    1   V 3 ILE 9  68  GLU 9  74  0                                        
SHEET    2   V 3 ARG 9  86  ASN 9  94 -1  O  VAL 9  90   N  GLU 9  71           
SHEET    3   V 3 VAL 9 130  TYR 9 131 -1  O  TYR 9 131   N  ILE 9  93           
SHEET    1   W 6 ARG 7  30  ASP 7  36  0                                        
SHEET    2   W 6 ILE 7  54  SER 7  60 -1  O  THR 7  56   N  GLU 7  34           
SHEET    3   W 6 PRO 7  66  VAL 7  72 -1  O  PHE 7  67   N  LEU 7  59           
SHEET    4   W 6 ILE 7  82  LEU 7  86 -1  O  GLY 7  83   N  ASP 7  71           
SHEET    5   W 6 ILE 7  91  GLU 7  98 -1  O  LEU 7  93   N  LEU 7  84           
SHEET    6   W 6 GLY 7 102  VAL 7 104 -1  O  GLY 7 102   N  GLU 7  98           
SHEET    1   X 4 ASP A 170  ARG A 175  0                                        
SHEET    2   X 4 ALA A 127  VAL A 134  1  N  ILE A 132   O  HIS A 172           
SHEET    3   X 4 HIS A  87  ALA A  93  1  N  CYS A  91   O  TYR A 131           
SHEET    4   X 4 THR A 216  ASN A 220  1  O  ASN A 219   N  ASN A  92           
SHEET    1   Y 5 GLY A 262  PRO A 267  0                                        
SHEET    2   Y 5 MET A 249  SER A 255 -1  N  TYR A 252   O  TYR A 264           
SHEET    3   Y 5 GLY A 327  PRO A 332  1  O  VAL A 328   N  GLN A 253           
SHEET    4   Y 5 ILE A 287  ILE A 291 -1  N  GLN A 288   O  ILE A 331           
SHEET    5   Y 5 LEU A 300  PRO A 301 -1  O  LEU A 300   N  ILE A 290           
SHEET    1   Z 3 PHE B 117  VAL B 122  0                                        
SHEET    2   Z 3 TYR B  78  CYS B  83  1  N  VAL B  82   O  VAL B 122           
SHEET    3   Z 3 ILE B 134  GLN B 135 -1  O  GLN B 135   N  GLN B  81           
SHEET    1  AA 2 VAL C   2  LYS C   5  0                                        
SHEET    2  AA 2 ILE C  10  VAL C  13 -1  O  VAL C  11   N  VAL C   4           
SHEET    1  AB 3 ALA C  80  ALA C  81  0                                        
SHEET    2  AB 3 LEU C  49  GLY C  53 -1  N  VAL C  50   O  ALA C  80           
SHEET    3  AB 3 VAL C  92  ASP C  94 -1  O  ASP C  94   N  ARG C  51           
SHEET    1  AC 2 HIS C 168  PRO C 169  0                                        
SHEET    2  AC 2 LEU C 176  ASP C 177 -1  O  ASP C 177   N  HIS C 168           
SHEET    1  AD 3 GLU C 250  THR C 254  0                                        
SHEET    2  AD 3 ILE C 265  ARG C 270 -1  O  ILE C 265   N  THR C 254           
SHEET    3  AD 3 GLU C 273  ALA C 279 -1  O  ARG C 278   N  THR C 266           
SHEET    1  AE 2 LEU C 310  ARG C 312  0                                        
SHEET    2  AE 2 LEU C 317  GLU C 319 -1  O  VAL C 318   N  VAL C 311           
SHEET    1  AF 5 LEU C 369  PHE C 371  0                                        
SHEET    2  AF 5 GLY C 342  LEU C 345  1  N  LEU C 345   O  ASP C 370           
SHEET    3  AF 5 ALA C 566  TYR C 568  1  O  TYR C 567   N  GLY C 342           
SHEET    4  AF 5 VAL C 583  MET C 585  1  O  VAL C 584   N  TYR C 568           
SHEET    5  AF 5 VAL C 600  VAL C 601  1  O  VAL C 600   N  MET C 585           
SHEET    1  AG 5 ILE C 464  VAL C 467  0                                        
SHEET    2  AG 5 MET C 448  ALA C 452  1  N  LEU C 450   O  ILE C 464           
SHEET    3  AG 5 ALA C 396  LEU C 399  1  N  VAL C 398   O  ALA C 449           
SHEET    4  AG 5 VAL C 504  LEU C 507  1  O  ILE C 506   N  LEU C 397           
SHEET    5  AG 5 LYS C 531  ALA C 534  1  O  LEU C 533   N  LEU C 505           
SHEET    1  AH 2 GLY C 612  VAL C 615  0                                        
SHEET    2  AH 2 VAL C 621  LEU C 624 -1  O  LEU C 622   N  LEU C 614           
SHEET    1  AI 2 PHE C 692  TYR C 693  0                                        
SHEET    2  AI 2 LEU C 760  SER C 761 -1  O  SER C 761   N  PHE C 692           
SHEET    1  AJ 2 GLN C 733  THR C 738  0                                        
SHEET    2  AJ 2 GLY C 741  ARG C 746 -1  O  GLY C 741   N  THR C 738           
SHEET    1  AK 3 SER D  36  HIS D  38  0                                        
SHEET    2  AK 3 MET D  44  THR D  46 -1  O  VAL D  45   N  THR D  37           
SHEET    3  AK 3 VAL D  56  HIS D  58 -1  O  VAL D  56   N  THR D  46           
SHEET    1  AL 2 ILE D 173  ARG D 174  0                                        
SHEET    2  AL 2 GLY D 177  VAL D 178 -1  O  GLY D 177   N  ARG D 174           
SHEET    1  AM 3 VAL D 342  THR D 346  0                                        
SHEET    2  AM 3 LEU D 353  VAL D 358 -1  O  LEU D 353   N  THR D 346           
SHEET    3  AM 3 ARG D 367  VAL D 370 -1  O  LYS D 369   N  TYR D 356           
SHEET    1  AN 5 ILE E  17  ASP E  19  0                                        
SHEET    2  AN 5 LEU E  25  VAL E  28 -1  O  TRP E  26   N  GLU E  18           
SHEET    3  AN 5 ARG E  87  VAL E  94  1  O  ARG E  91   N  VAL E  27           
SHEET    4  AN 5 PHE E  68  VAL E  75 -1  N  PHE E  68   O  VAL E  94           
SHEET    5  AN 5 ILE E  52  ASP E  56 -1  N  LEU E  55   O  ALA E  69           
SHEET    1  AO 2 THR E 157  LEU E 158  0                                        
SHEET    2  AO 2 TYR E 164  ILE E 165 -1  O  ILE E 165   N  THR E 157           
SHEET    1  AP 4 PHE F  41  GLY F  42  0                                        
SHEET    2  AP 4 MET F  78  ALA F  81  1  O  ILE F  79   N  PHE F  41           
SHEET    3  AP 4 VAL F 105  MET F 108  1  O  MET F 108   N  VAL F  80           
SHEET    4  AP 4 VAL F 135  VAL F 137  1  O  VAL F 137   N  SER F 107           
SHEET    1  AQ 2 VAL G  31  ALA G  32  0                                        
SHEET    2  AQ 2 TYR G 161  VAL G 162  1  O  VAL G 162   N  VAL G  31           
SHEET    1  AR 2 HIS G  41  LEU G  43  0                                        
SHEET    2  AR 2 ILE G 113  LEU G 115 -1  O  VAL G 114   N  VAL G  42           
SHEET    1  AS 3 ILE G  68  GLU G  74  0                                        
SHEET    2  AS 3 ARG G  86  ASN G  94 -1  O  TYR G  87   N  ALA G  73           
SHEET    3  AS 3 VAL G 130  TYR G 131 -1  O  TYR G 131   N  ILE G  93           
SHEET    1  AT 6 ARG H  30  ASP H  36  0                                        
SHEET    2  AT 6 ILE H  54  SER H  60 -1  O  SER H  60   N  ARG H  30           
SHEET    3  AT 6 PRO H  66  VAL H  72 -1  O  ALA H  70   N  ALA H  57           
SHEET    4  AT 6 ILE H  82  LEU H  86 -1  O  GLY H  83   N  ASP H  71           
SHEET    5  AT 6 ILE H  91  GLU H  98 -1  O  LEU H  93   N  LEU H  84           
SHEET    6  AT 6 GLY H 102  VAL H 104 -1  O  GLY H 102   N  GLU H  98           
SHEET    1  AU 4 ASP J 170  ARG J 175  0                                        
SHEET    2  AU 4 ALA J 127  VAL J 134  1  N  ILE J 132   O  HIS J 172           
SHEET    3  AU 4 HIS J  87  ALA J  93  1  N  CYS J  91   O  TYR J 131           
SHEET    4  AU 4 THR J 216  ASN J 220  1  O  ASN J 219   N  ASN J  92           
SHEET    1  AV 5 GLY J 262  PRO J 267  0                                        
SHEET    2  AV 5 MET J 249  SER J 255 -1  N  TYR J 252   O  TYR J 264           
SHEET    3  AV 5 GLY J 327  PRO J 332  1  O  VAL J 328   N  GLN J 253           
SHEET    4  AV 5 ILE J 287  ILE J 291 -1  N  GLN J 288   O  ILE J 331           
SHEET    5  AV 5 LEU J 300  PRO J 301 -1  O  LEU J 300   N  ILE J 290           
SHEET    1  AW 3 PHE K 117  VAL K 122  0                                        
SHEET    2  AW 3 TYR K  78  CYS K  83  1  N  VAL K  82   O  VAL K 122           
SHEET    3  AW 3 ILE K 134  GLN K 135 -1  O  GLN K 135   N  GLN K  81           
SHEET    1  AX 2 VAL L   2  LYS L   5  0                                        
SHEET    2  AX 2 ILE L  10  VAL L  13 -1  O  VAL L  11   N  VAL L   4           
SHEET    1  AY 3 ALA L  80  ALA L  81  0                                        
SHEET    2  AY 3 LEU L  49  GLY L  53 -1  N  VAL L  50   O  ALA L  80           
SHEET    3  AY 3 VAL L  92  ASP L  94 -1  O  ASP L  94   N  ARG L  51           
SHEET    1  AZ 2 HIS L 168  PRO L 169  0                                        
SHEET    2  AZ 2 LEU L 176  ASP L 177 -1  O  ASP L 177   N  HIS L 168           
SHEET    1  BA 3 GLU L 250  THR L 254  0                                        
SHEET    2  BA 3 ILE L 265  ARG L 270 -1  O  ALA L 267   N  THR L 252           
SHEET    3  BA 3 GLU L 273  ALA L 279 -1  O  ARG L 278   N  THR L 266           
SHEET    1  BB 2 LEU L 310  ARG L 312  0                                        
SHEET    2  BB 2 LEU L 317  GLU L 319 -1  O  VAL L 318   N  VAL L 311           
SHEET    1  BC 5 LEU L 369  PHE L 371  0                                        
SHEET    2  BC 5 GLY L 342  LEU L 345  1  N  LEU L 345   O  ASP L 370           
SHEET    3  BC 5 ALA L 566  TYR L 568  1  O  TYR L 567   N  GLY L 342           
SHEET    4  BC 5 VAL L 583  MET L 585  1  O  VAL L 584   N  TYR L 568           
SHEET    5  BC 5 VAL L 600  VAL L 601  1  O  VAL L 600   N  MET L 585           
SHEET    1  BD 5 ILE L 464  VAL L 467  0                                        
SHEET    2  BD 5 MET L 448  ALA L 452  1  N  LEU L 450   O  GLU L 466           
SHEET    3  BD 5 ALA L 396  LEU L 399  1  N  VAL L 398   O  ALA L 449           
SHEET    4  BD 5 VAL L 504  LEU L 507  1  O  ILE L 506   N  LEU L 397           
SHEET    5  BD 5 LYS L 531  ALA L 534  1  O  LEU L 533   N  LEU L 505           
SHEET    1  BE 2 GLY L 612  VAL L 615  0                                        
SHEET    2  BE 2 VAL L 621  LEU L 624 -1  O  LEU L 622   N  LEU L 614           
SHEET    1  BF 2 PHE L 692  TYR L 693  0                                        
SHEET    2  BF 2 LEU L 760  SER L 761 -1  O  SER L 761   N  PHE L 692           
SHEET    1  BG 2 GLN L 733  THR L 738  0                                        
SHEET    2  BG 2 GLY L 741  ARG L 746 -1  O  GLY L 741   N  THR L 738           
SHEET    1  BH 3 SER M  36  HIS M  38  0                                        
SHEET    2  BH 3 MET M  44  THR M  46 -1  O  VAL M  45   N  THR M  37           
SHEET    3  BH 3 VAL M  56  HIS M  58 -1  O  VAL M  56   N  THR M  46           
SHEET    1  BI 3 VAL M 344  THR M 346  0                                        
SHEET    2  BI 3 LEU M 353  VAL M 358 -1  O  LEU M 353   N  THR M 346           
SHEET    3  BI 3 ARG M 367  VAL M 370 -1  O  LYS M 369   N  TYR M 356           
SHEET    1  BJ 5 ILE N  17  ASP N  19  0                                        
SHEET    2  BJ 5 LEU N  25  VAL N  28 -1  O  TRP N  26   N  GLU N  18           
SHEET    3  BJ 5 ARG N  87  VAL N  94  1  O  ARG N  91   N  VAL N  27           
SHEET    4  BJ 5 PHE N  68  VAL N  75 -1  N  PHE N  68   O  VAL N  94           
SHEET    5  BJ 5 ILE N  52  ASP N  56 -1  N  LEU N  55   O  ALA N  69           
SHEET    1  BK 2 THR N 157  LEU N 158  0                                        
SHEET    2  BK 2 TYR N 164  ILE N 165 -1  O  ILE N 165   N  THR N 157           
SHEET    1  BL 4 PHE O  41  GLY O  42  0                                        
SHEET    2  BL 4 MET O  78  ALA O  81  1  O  ILE O  79   N  PHE O  41           
SHEET    3  BL 4 VAL O 105  MET O 108  1  O  MET O 108   N  VAL O  80           
SHEET    4  BL 4 VAL O 135  VAL O 137  1  O  VAL O 137   N  SER O 107           
SHEET    1  BM 2 VAL P  31  ALA P  32  0                                        
SHEET    2  BM 2 TYR P 161  VAL P 162  1  O  VAL P 162   N  VAL P  31           
SHEET    1  BN 2 HIS P  41  LEU P  43  0                                        
SHEET    2  BN 2 ILE P 113  LEU P 115 -1  O  VAL P 114   N  VAL P  42           
SHEET    1  BO 3 ILE P  68  GLU P  74  0                                        
SHEET    2  BO 3 ARG P  86  ASN P  94 -1  O  TYR P  87   N  ALA P  73           
SHEET    3  BO 3 VAL P 130  TYR P 131 -1  O  TYR P 131   N  ILE P  93           
SHEET    1  BP 6 ARG Q  30  ASP Q  36  0                                        
SHEET    2  BP 6 ILE Q  54  SER Q  60 -1  O  SER Q  60   N  ARG Q  30           
SHEET    3  BP 6 PRO Q  66  VAL Q  72 -1  O  PHE Q  67   N  LEU Q  59           
SHEET    4  BP 6 ILE Q  82  LEU Q  86 -1  O  GLY Q  83   N  ASP Q  71           
SHEET    5  BP 6 ILE Q  91  GLU Q  98 -1  O  LEU Q  93   N  LEU Q  84           
SHEET    6  BP 6 GLY Q 102  VAL Q 104 -1  O  GLY Q 102   N  GLU Q  98           
SHEET    1  BQ 4 ASP S 170  ARG S 175  0                                        
SHEET    2  BQ 4 ALA S 127  VAL S 134  1  N  ILE S 132   O  HIS S 172           
SHEET    3  BQ 4 HIS S  87  ALA S  93  1  N  CYS S  91   O  TYR S 131           
SHEET    4  BQ 4 THR S 216  ASN S 220  1  O  ASN S 219   N  ASN S  92           
SHEET    1  BR 5 GLY S 262  PRO S 267  0                                        
SHEET    2  BR 5 MET S 249  SER S 255 -1  N  TYR S 252   O  TYR S 264           
SHEET    3  BR 5 GLY S 327  PRO S 332  1  O  VAL S 328   N  GLN S 253           
SHEET    4  BR 5 ILE S 287  ILE S 291 -1  N  GLN S 288   O  ILE S 331           
SHEET    5  BR 5 LEU S 300  PRO S 301 -1  O  LEU S 300   N  ILE S 290           
SHEET    1  BS 3 PHE T 117  VAL T 122  0                                        
SHEET    2  BS 3 TYR T  78  CYS T  83  1  N  VAL T  82   O  VAL T 122           
SHEET    3  BS 3 ILE T 134  GLN T 135 -1  O  GLN T 135   N  GLN T  81           
SHEET    1  BT 2 VAL U   2  LYS U   5  0                                        
SHEET    2  BT 2 ILE U  10  VAL U  13 -1  O  VAL U  11   N  VAL U   4           
SHEET    1  BU 3 ALA U  80  ALA U  81  0                                        
SHEET    2  BU 3 LEU U  49  GLY U  53 -1  N  VAL U  50   O  ALA U  80           
SHEET    3  BU 3 VAL U  92  ASP U  94 -1  O  ASP U  94   N  ARG U  51           
SHEET    1  BV 2 HIS U 168  PRO U 169  0                                        
SHEET    2  BV 2 LEU U 176  ASP U 177 -1  O  ASP U 177   N  HIS U 168           
SHEET    1  BW 3 GLU U 250  THR U 254  0                                        
SHEET    2  BW 3 ILE U 265  ARG U 270 -1  O  ILE U 265   N  THR U 254           
SHEET    3  BW 3 GLU U 273  ALA U 279 -1  O  ARG U 278   N  THR U 266           
SHEET    1  BX 2 LEU U 310  ARG U 312  0                                        
SHEET    2  BX 2 LEU U 317  GLU U 319 -1  O  VAL U 318   N  VAL U 311           
SHEET    1  BY 5 LEU U 369  PHE U 371  0                                        
SHEET    2  BY 5 GLY U 342  LEU U 345  1  N  LEU U 345   O  ASP U 370           
SHEET    3  BY 5 ALA U 566  TYR U 568  1  O  TYR U 567   N  GLY U 342           
SHEET    4  BY 5 VAL U 583  MET U 585  1  O  VAL U 584   N  TYR U 568           
SHEET    5  BY 5 VAL U 600  VAL U 601  1  O  VAL U 600   N  MET U 585           
SHEET    1  BZ 5 ILE U 464  VAL U 467  0                                        
SHEET    2  BZ 5 MET U 448  ALA U 452  1  N  LEU U 450   O  GLU U 466           
SHEET    3  BZ 5 ALA U 396  LEU U 399  1  N  VAL U 398   O  ALA U 449           
SHEET    4  BZ 5 VAL U 504  LEU U 507  1  O  ILE U 506   N  LEU U 397           
SHEET    5  BZ 5 LYS U 531  ALA U 534  1  O  LEU U 533   N  LEU U 505           
SHEET    1  CA 2 GLY U 612  VAL U 615  0                                        
SHEET    2  CA 2 VAL U 621  LEU U 624 -1  O  LEU U 622   N  LEU U 614           
SHEET    1  CB 2 PHE U 692  TYR U 693  0                                        
SHEET    2  CB 2 LEU U 760  SER U 761 -1  O  SER U 761   N  PHE U 692           
SHEET    1  CC 2 GLN U 733  THR U 738  0                                        
SHEET    2  CC 2 GLY U 741  ARG U 746 -1  O  GLY U 741   N  THR U 738           
SHEET    1  CD 3 SER V  36  HIS V  38  0                                        
SHEET    2  CD 3 MET V  44  LEU V  47 -1  O  VAL V  45   N  THR V  37           
SHEET    3  CD 3 VAL V  55  HIS V  58 -1  O  VAL V  56   N  THR V  46           
SHEET    1  CE 2 ILE V 173  ARG V 174  0                                        
SHEET    2  CE 2 GLY V 177  VAL V 178 -1  O  GLY V 177   N  ARG V 174           
SHEET    1  CF 2 TYR V 355  VAL V 358  0                                        
SHEET    2  CF 2 ARG V 367  VAL V 370 -1  O  LYS V 369   N  TYR V 356           
SHEET    1  CG 5 ILE W  17  ASP W  19  0                                        
SHEET    2  CG 5 LEU W  25  VAL W  28 -1  O  TRP W  26   N  GLU W  18           
SHEET    3  CG 5 ARG W  87  VAL W  94  1  O  ARG W  91   N  VAL W  27           
SHEET    4  CG 5 PHE W  68  VAL W  75 -1  N  PHE W  68   O  VAL W  94           
SHEET    5  CG 5 ILE W  52  ASP W  56 -1  N  LEU W  55   O  ALA W  69           
SHEET    1  CH 2 THR W 157  LEU W 158  0                                        
SHEET    2  CH 2 TYR W 164  ILE W 165 -1  O  ILE W 165   N  THR W 157           
SHEET    1  CI 4 PHE X  41  GLY X  42  0                                        
SHEET    2  CI 4 MET X  78  ALA X  81  1  O  ILE X  79   N  PHE X  41           
SHEET    3  CI 4 VAL X 105  MET X 108  1  O  MET X 108   N  VAL X  80           
SHEET    4  CI 4 VAL X 135  VAL X 137  1  O  VAL X 137   N  SER X 107           
SHEET    1  CJ 2 VAL Y  31  ALA Y  32  0                                        
SHEET    2  CJ 2 TYR Y 161  VAL Y 162  1  O  VAL Y 162   N  VAL Y  31           
SHEET    1  CK 2 HIS Y  41  LEU Y  43  0                                        
SHEET    2  CK 2 ILE Y 113  LEU Y 115 -1  O  VAL Y 114   N  VAL Y  42           
SHEET    1  CL 3 ILE Y  68  GLU Y  74  0                                        
SHEET    2  CL 3 ARG Y  86  ASN Y  94 -1  O  VAL Y  90   N  GLU Y  71           
SHEET    3  CL 3 VAL Y 130  TYR Y 131 -1  O  TYR Y 131   N  ILE Y  93           
SHEET    1  CM 6 ARG Z  30  ASP Z  36  0                                        
SHEET    2  CM 6 ILE Z  54  SER Z  60 -1  O  SER Z  60   N  ARG Z  30           
SHEET    3  CM 6 PRO Z  66  VAL Z  72 -1  O  PHE Z  67   N  LEU Z  59           
SHEET    4  CM 6 ILE Z  82  LEU Z  86 -1  O  GLY Z  83   N  ASP Z  71           
SHEET    5  CM 6 ILE Z  91  GLU Z  98 -1  O  LEU Z  93   N  LEU Z  84           
SHEET    6  CM 6 GLY Z 102  VAL Z 104 -1  O  GLY Z 102   N  GLU Z  98           
SSBOND   1 CYS 2  144    CYS 2  172                          1555   1555  2.02  
SSBOND   2 CYS B  144    CYS B  172                          1555   1555  2.03  
SSBOND   3 CYS K  144    CYS K  172                          1555   1555  2.01  
SSBOND   4 CYS T  144    CYS T  172                          1555   1555  2.02  
LINK        FE1  SF4 6 182                 SG  CYS 6 140     1555   1555  2.30  
LINK        FE2  SF4 6 182                 SG  CYS 6  46     1555   1555  2.29  
LINK        FE3  SF4 6 182                 SG  CYS 6 111     1555   1555  2.15  
LINK        FE4  SF4 6 182                 SG  CYS 6  45     1555   1555  2.23  
LINK        FE1  SF4 9 183                 SG  CYS 9  63     1555   1555  2.23  
LINK        FE2  SF4 9 183                 SG  CYS 9  98     1555   1555  2.28  
LINK        FE3  SF4 9 183                 SG  CYS 9 101     1555   1555  2.33  
LINK        FE4  SF4 9 183                 SG  CYS 9 104     1555   1555  2.21  
LINK        FE1  SF4 9 184                 SG  CYS 9  56     1555   1555  2.37  
LINK        FE2  SF4 9 184                 SG  CYS 9  59     1555   1555  2.24  
LINK        FE3  SF4 9 184                 SG  CYS 9 108     1555   1555  2.23  
LINK        FE4  SF4 9 184                 SG  CYS 9  53     1555   1555  2.16  
LINK        FE1  SF4 3 784                 SG  CYS 3 122     1555   1555  2.27  
LINK        FE2  SF4 3 784                 SG  CYS 3 119     1555   1555  2.29  
LINK        FE3  SF4 3 784                 SG  CYS 3 128     1555   1555  2.22  
LINK        FE4  SF4 3 784                 NE2 HIS 3 115     1555   1555  2.12  
LINK        FE1  SF4 3 785                 SG  CYS 3 230     1555   1555  2.29  
LINK        FE2  SF4 3 785                 SG  CYS 3 181     1555   1555  2.24  
LINK        FE3  SF4 3 785                 SG  CYS 3 184     1555   1555  2.23  
LINK        FE4  SF4 3 785                 SG  CYS 3 187     1555   1555  2.31  
LINK        FE1  SF4 3 786                 SG  CYS 3 259     1555   1555  2.29  
LINK        FE2  SF4 3 786                 SG  CYS 3 291     1555   1555  2.20  
LINK        FE3  SF4 3 786                 SG  CYS 3 256     1555   1555  2.33  
LINK        FE4  SF4 3 786                 SG  CYS 3 263     1555   1555  2.23  
LINK        FE1  FES 3 787                 SG  CYS 3  45     1555   1555  2.25  
LINK        FE2  FES 3 787                 SG  CYS 3  83     1555   1555  2.26  
LINK        FE1  FES 3 787                 SG  CYS 3  34     1555   1555  2.29  
LINK        FE2  FES 3 787                 SG  CYS 3  48     1555   1555  2.29  
LINK        FE1  SF4 1 439                 SG  CYS 1 353     1555   1555  2.28  
LINK        FE2  SF4 1 439                 SG  CYS 1 359     1555   1555  2.21  
LINK        FE3  SF4 1 439                 SG  CYS 1 356     1555   1555  2.26  
LINK        FE4  SF4 1 439                 SG  CYS 1 400     1555   1555  2.26  
LINK        FE1  FES 2 182                 SG  CYS 2  83     1555   1555  2.34  
LINK        FE2  FES 2 182                 SG  CYS 2 124     1555   1555  2.28  
LINK        FE1  FES 2 182                 SG  CYS 2  88     1555   1555  2.24  
LINK        FE2  FES 2 182                 SG  CYS 2 128     1555   1555  2.29  
LINK        FE1  SF4 F 182                 SG  CYS F 140     1555   1555  2.32  
LINK        FE2  SF4 F 182                 SG  CYS F  46     1555   1555  2.29  
LINK        FE3  SF4 F 182                 SG  CYS F 111     1555   1555  2.19  
LINK        FE4  SF4 F 182                 SG  CYS F  45     1555   1555  2.24  
LINK        FE1  SF4 G 183                 SG  CYS G  63     1555   1555  2.18  
LINK        FE2  SF4 G 183                 SG  CYS G  98     1555   1555  2.32  
LINK        FE3  SF4 G 183                 SG  CYS G 101     1555   1555  2.33  
LINK        FE4  SF4 G 183                 SG  CYS G 104     1555   1555  2.26  
LINK        FE1  SF4 G 184                 SG  CYS G  56     1555   1555  2.30  
LINK        FE2  SF4 G 184                 SG  CYS G  59     1555   1555  2.26  
LINK        FE3  SF4 G 184                 SG  CYS G 108     1555   1555  2.20  
LINK        FE4  SF4 G 184                 SG  CYS G  53     1555   1555  2.31  
LINK        FE1  SF4 C 784                 SG  CYS C 122     1555   1555  2.22  
LINK        FE2  SF4 C 784                 SG  CYS C 119     1555   1555  2.26  
LINK        FE3  SF4 C 784                 SG  CYS C 128     1555   1555  2.16  
LINK        FE4  SF4 C 784                 NE2 HIS C 115     1555   1555  2.14  
LINK        FE1  SF4 C 785                 SG  CYS C 230     1555   1555  2.24  
LINK        FE2  SF4 C 785                 SG  CYS C 181     1555   1555  2.26  
LINK        FE3  SF4 C 785                 SG  CYS C 184     1555   1555  2.27  
LINK        FE4  SF4 C 785                 SG  CYS C 187     1555   1555  2.22  
LINK        FE1  SF4 C 786                 SG  CYS C 259     1555   1555  2.20  
LINK        FE2  SF4 C 786                 SG  CYS C 291     1555   1555  2.25  
LINK        FE3  SF4 C 786                 SG  CYS C 256     1555   1555  2.33  
LINK        FE4  SF4 C 786                 SG  CYS C 263     1555   1555  2.26  
LINK        FE1  FES C 787                 SG  CYS C  45     1555   1555  2.30  
LINK        FE2  FES C 787                 SG  CYS C  83     1555   1555  2.21  
LINK        FE1  FES C 787                 SG  CYS C  34     1555   1555  2.26  
LINK        FE2  FES C 787                 SG  CYS C  48     1555   1555  2.30  
LINK        FE1  SF4 A 439                 SG  CYS A 353     1555   1555  2.23  
LINK        FE2  SF4 A 439                 SG  CYS A 359     1555   1555  2.23  
LINK        FE3  SF4 A 439                 SG  CYS A 356     1555   1555  2.22  
LINK        FE4  SF4 A 439                 SG  CYS A 400     1555   1555  2.24  
LINK        FE1  FES B 182                 SG  CYS B  83     1555   1555  2.33  
LINK        FE2  FES B 182                 SG  CYS B 124     1555   1555  2.28  
LINK        FE1  FES B 182                 SG  CYS B  88     1555   1555  2.25  
LINK        FE2  FES B 182                 SG  CYS B 128     1555   1555  2.30  
LINK        FE1  SF4 O 182                 SG  CYS O 140     1555   1555  2.27  
LINK        FE2  SF4 O 182                 SG  CYS O  46     1555   1555  2.28  
LINK        FE3  SF4 O 182                 SG  CYS O 111     1555   1555  2.20  
LINK        FE4  SF4 O 182                 SG  CYS O  45     1555   1555  2.24  
LINK        FE1  SF4 P 183                 SG  CYS P  63     1555   1555  2.28  
LINK        FE2  SF4 P 183                 SG  CYS P  98     1555   1555  2.31  
LINK        FE3  SF4 P 183                 SG  CYS P 101     1555   1555  2.36  
LINK        FE4  SF4 P 183                 SG  CYS P 104     1555   1555  2.26  
LINK        FE1  SF4 P 184                 SG  CYS P  56     1555   1555  2.36  
LINK        FE2  SF4 P 184                 SG  CYS P  59     1555   1555  2.29  
LINK        FE3  SF4 P 184                 SG  CYS P 108     1555   1555  2.25  
LINK        FE4  SF4 P 184                 SG  CYS P  53     1555   1555  2.22  
LINK        FE1  SF4 L 784                 SG  CYS L 122     1555   1555  2.25  
LINK        FE2  SF4 L 784                 SG  CYS L 119     1555   1555  2.28  
LINK        FE3  SF4 L 784                 SG  CYS L 128     1555   1555  2.25  
LINK        FE4  SF4 L 784                 NE2 HIS L 115     1555   1555  2.11  
LINK        FE1  SF4 L 785                 SG  CYS L 230     1555   1555  2.27  
LINK        FE2  SF4 L 785                 SG  CYS L 181     1555   1555  2.23  
LINK        FE3  SF4 L 785                 SG  CYS L 184     1555   1555  2.26  
LINK        FE4  SF4 L 785                 SG  CYS L 187     1555   1555  2.31  
LINK        FE1  SF4 L 786                 SG  CYS L 259     1555   1555  2.27  
LINK        FE2  SF4 L 786                 SG  CYS L 291     1555   1555  2.23  
LINK        FE3  SF4 L 786                 SG  CYS L 256     1555   1555  2.30  
LINK        FE4  SF4 L 786                 SG  CYS L 263     1555   1555  2.21  
LINK        FE1  FES L 787                 SG  CYS L  45     1555   1555  2.26  
LINK        FE2  FES L 787                 SG  CYS L  83     1555   1555  2.30  
LINK        FE1  FES L 787                 SG  CYS L  34     1555   1555  2.32  
LINK        FE2  FES L 787                 SG  CYS L  48     1555   1555  2.30  
LINK        FE1  SF4 J 439                 SG  CYS J 353     1555   1555  2.26  
LINK        FE2  SF4 J 439                 SG  CYS J 359     1555   1555  2.21  
LINK        FE3  SF4 J 439                 SG  CYS J 356     1555   1555  2.21  
LINK        FE4  SF4 J 439                 SG  CYS J 400     1555   1555  2.27  
LINK        FE1  FES K 182                 SG  CYS K  83     1555   1555  2.31  
LINK        FE2  FES K 182                 SG  CYS K 124     1555   1555  2.27  
LINK        FE1  FES K 182                 SG  CYS K  88     1555   1555  2.24  
LINK        FE2  FES K 182                 SG  CYS K 128     1555   1555  2.30  
LINK        FE1  SF4 X 182                 SG  CYS X 140     1555   1555  2.26  
LINK        FE2  SF4 X 182                 SG  CYS X  46     1555   1555  2.27  
LINK        FE3  SF4 X 182                 SG  CYS X 111     1555   1555  2.13  
LINK        FE4  SF4 X 182                 SG  CYS X  45     1555   1555  2.26  
LINK        FE1  SF4 Y 183                 SG  CYS Y  63     1555   1555  2.21  
LINK        FE2  SF4 Y 183                 SG  CYS Y  98     1555   1555  2.31  
LINK        FE3  SF4 Y 183                 SG  CYS Y 101     1555   1555  2.34  
LINK        FE4  SF4 Y 183                 SG  CYS Y 104     1555   1555  2.23  
LINK        FE1  SF4 Y 184                 SG  CYS Y  56     1555   1555  2.32  
LINK        FE2  SF4 Y 184                 SG  CYS Y  59     1555   1555  2.24  
LINK        FE3  SF4 Y 184                 SG  CYS Y 108     1555   1555  2.25  
LINK        FE4  SF4 Y 184                 SG  CYS Y  53     1555   1555  2.25  
LINK        FE1  SF4 U 784                 SG  CYS U 122     1555   1555  2.24  
LINK        FE2  SF4 U 784                 SG  CYS U 119     1555   1555  2.35  
LINK        FE3  SF4 U 784                 SG  CYS U 128     1555   1555  2.19  
LINK        FE4  SF4 U 784                 NE2 HIS U 115     1555   1555  2.09  
LINK        FE1  SF4 U 785                 SG  CYS U 230     1555   1555  2.27  
LINK        FE2  SF4 U 785                 SG  CYS U 181     1555   1555  2.25  
LINK        FE3  SF4 U 785                 SG  CYS U 184     1555   1555  2.28  
LINK        FE4  SF4 U 785                 SG  CYS U 187     1555   1555  2.24  
LINK        FE1  SF4 U 786                 SG  CYS U 259     1555   1555  2.22  
LINK        FE2  SF4 U 786                 SG  CYS U 291     1555   1555  2.28  
LINK        FE3  SF4 U 786                 SG  CYS U 256     1555   1555  2.28  
LINK        FE4  SF4 U 786                 SG  CYS U 263     1555   1555  2.27  
LINK        FE1  FES U 787                 SG  CYS U  45     1555   1555  2.29  
LINK        FE2  FES U 787                 SG  CYS U  83     1555   1555  2.23  
LINK        FE1  FES U 787                 SG  CYS U  34     1555   1555  2.29  
LINK        FE2  FES U 787                 SG  CYS U  48     1555   1555  2.30  
LINK        FE1  SF4 S 439                 SG  CYS S 353     1555   1555  2.29  
LINK        FE2  SF4 S 439                 SG  CYS S 359     1555   1555  2.25  
LINK        FE3  SF4 S 439                 SG  CYS S 356     1555   1555  2.15  
LINK        FE4  SF4 S 439                 SG  CYS S 400     1555   1555  2.22  
LINK        FE1  FES T 182                 SG  CYS T  83     1555   1555  2.30  
LINK        FE2  FES T 182                 SG  CYS T 124     1555   1555  2.29  
LINK        FE1  FES T 182                 SG  CYS T  88     1555   1555  2.25  
LINK        FE2  FES T 182                 SG  CYS T 128     1555   1555  2.28  
LINK         O   CYS G  56                FE1  SF4 G 184     1555   1555  2.60  
LINK         O   CYS Y  56                FE1  SF4 Y 184     1555   1555  2.55  
CISPEP   1 CYS 6  140    PRO 6  141          0        -0.71                     
CISPEP   2 CYS F  140    PRO F  141          0        -0.63                     
CISPEP   3 CYS O  140    PRO O  141          0        -0.52                     
CISPEP   4 CYS X  140    PRO X  141          0        -0.75                     
SITE     1 AC1  9 ARG 4  84  HIS 4 169  CYS 6  45  CYS 6  46                    
SITE     2 AC1  9 GLY 6  82  ALA 6 110  CYS 6 111  CYS 6 140                    
SITE     3 AC1  9 PRO 6 141                                                     
SITE     1 AC2  8 HIS 9  41  CYS 9  63  PRO 9  64  CYS 9  98                    
SITE     2 AC2  8 ILE 9  99  PHE 9 100  CYS 9 101  CYS 9 104                    
SITE     1 AC3  6 CYS 9  53  ILE 9  54  CYS 9  56  CYS 9  59                    
SITE     2 AC3  6 CYS 9 108  THR 9 110                                          
SITE     1 AC4  8 HIS 3 115  ASP 3 118  CYS 3 119  CYS 3 122                    
SITE     2 AC4  8 CYS 3 128  GLN 3 131  VAL 3 232  GLY 3 233                    
SITE     1 AC5  7 CYS 3 181  ILE 3 182  CYS 3 184  CYS 3 187                    
SITE     2 AC5  7 CYS 3 230  VAL 3 232  LEU 3 235                               
SITE     1 AC6  8 CYS 3 256  LEU 3 258  CYS 3 259  VAL 3 261                    
SITE     2 AC6  8 CYS 3 263  ILE 3 290  CYS 3 291  PRO 3 407                    
SITE     1 AC7  7 CYS 3  34  SER 3  35  GLY 3  43  ALA 3  44                    
SITE     2 AC7  7 CYS 3  45  CYS 3  48  CYS 3  83                               
SITE     1 AC8  9 PRO 1 199  SER 1 352  CYS 1 353  GLY 1 354                    
SITE     2 AC8  9 LYS 1 355  CYS 1 356  CYS 1 359  PHE 1 399                    
SITE     3 AC8  9 CYS 1 400                                                     
SITE     1 AC9  8 CYS 2  83  SER 2  87  CYS 2  88  CYS 2 124                    
SITE     2 AC9  8 LEU 2 125  GLY 2 126  SER 2 127  CYS 2 128                    
SITE     1 BC1 15 GLY 1  64  GLY 1  66  THR 1  72  LYS 1  75                    
SITE     2 BC1 15 ASN 1  92  ASP 1  94  GLU 1  95  SER 1  96                    
SITE     3 BC1 15 GLU 1  97  TYR 1 180  GLY 1 183  ILE 1 218                    
SITE     4 BC1 15 ASN 1 219  ASN 1 220  THR 1 223                               
SITE     1 BC2  8 ARG D  84  CYS F  45  CYS F  46  GLY F  82                    
SITE     2 BC2  8 ALA F 110  CYS F 111  CYS F 140  PRO F 141                    
SITE     1 BC3  8 HIS G  41  CYS G  63  PRO G  64  CYS G  98                    
SITE     2 BC3  8 ILE G  99  PHE G 100  CYS G 101  CYS G 104                    
SITE     1 BC4  8 CYS G  53  ILE G  54  CYS G  56  CYS G  59                    
SITE     2 BC4  8 CYS G 108  PRO G 109  THR G 110  ILE G 113                    
SITE     1 BC5  8 HIS C 115  ASP C 118  CYS C 119  CYS C 122                    
SITE     2 BC5  8 CYS C 128  GLN C 131  VAL C 232  GLY C 233                    
SITE     1 BC6  7 CYS C 181  ILE C 182  CYS C 184  CYS C 187                    
SITE     2 BC6  7 CYS C 230  VAL C 232  LEU C 235                               
SITE     1 BC7  9 CYS C 256  LEU C 258  CYS C 259  VAL C 261                    
SITE     2 BC7  9 GLY C 262  CYS C 263  ILE C 290  CYS C 291                    
SITE     3 BC7  9 PRO C 407                                                     
SITE     1 BC8  7 CYS C  34  SER C  35  GLY C  43  ALA C  44                    
SITE     2 BC8  7 CYS C  45  CYS C  48  CYS C  83                               
SITE     1 BC9  9 PRO A 199  SER A 352  CYS A 353  GLY A 354                    
SITE     2 BC9  9 LYS A 355  CYS A 356  CYS A 359  CYS A 400                    
SITE     3 BC9  9 ALA A 403                                                     
SITE     1 CC1  8 CYS B  83  SER B  87  CYS B  88  CYS B 124                    
SITE     2 CC1  8 LEU B 125  GLY B 126  SER B 127  CYS B 128                    
SITE     1 CC2 14 GLY A  64  THR A  72  LYS A  75  ASN A  92                    
SITE     2 CC2 14 ASP A  94  GLU A  95  SER A  96  GLU A  97                    
SITE     3 CC2 14 TYR A 180  GLY A 183  ILE A 218  ASN A 219                    
SITE     4 CC2 14 ASN A 220  THR A 223                                          
SITE     1 CC3  9 ARG M  84  HIS M 169  CYS O  45  CYS O  46                    
SITE     2 CC3  9 GLY O  82  ALA O 110  CYS O 111  CYS O 140                    
SITE     3 CC3  9 PRO O 141                                                     
SITE     1 CC4  8 HIS P  41  CYS P  63  PRO P  64  CYS P  98                    
SITE     2 CC4  8 ILE P  99  PHE P 100  CYS P 101  CYS P 104                    
SITE     1 CC5  8 CYS P  53  ILE P  54  CYS P  56  CYS P  59                    
SITE     2 CC5  8 CYS P 108  PRO P 109  THR P 110  ILE P 113                    
SITE     1 CC6  8 HIS L 115  ASP L 118  CYS L 119  CYS L 122                    
SITE     2 CC6  8 CYS L 128  GLN L 131  VAL L 232  GLY L 233                    
SITE     1 CC7  7 CYS L 181  ILE L 182  CYS L 184  CYS L 187                    
SITE     2 CC7  7 CYS L 230  VAL L 232  LEU L 235                               
SITE     1 CC8  9 CYS L 256  LEU L 258  CYS L 259  VAL L 261                    
SITE     2 CC8  9 GLY L 262  CYS L 263  ILE L 290  CYS L 291                    
SITE     3 CC8  9 PRO L 407                                                     
SITE     1 CC9  8 CYS L  34  SER L  35  GLY L  43  ALA L  44                    
SITE     2 CC9  8 CYS L  45  MET L  47  CYS L  48  CYS L  83                    
SITE     1 DC1  9 PRO J 199  SER J 352  CYS J 353  GLY J 354                    
SITE     2 DC1  9 LYS J 355  CYS J 356  CYS J 359  CYS J 400                    
SITE     3 DC1  9 ALA J 403                                                     
SITE     1 DC2  8 CYS K  83  SER K  87  CYS K  88  CYS K 124                    
SITE     2 DC2  8 LEU K 125  GLY K 126  SER K 127  CYS K 128                    
SITE     1 DC3 14 GLY J  64  THR J  72  LYS J  75  ASN J  92                    
SITE     2 DC3 14 ASP J  94  GLU J  95  SER J  96  GLU J  97                    
SITE     3 DC3 14 TYR J 180  GLY J 183  ILE J 218  ASN J 219                    
SITE     4 DC3 14 ASN J 220  THR J 223                                          
SITE     1 DC4  8 ARG V  84  CYS X  45  CYS X  46  GLY X  82                    
SITE     2 DC4  8 ALA X 110  CYS X 111  CYS X 140  PRO X 141                    
SITE     1 DC5  8 HIS Y  41  CYS Y  63  PRO Y  64  CYS Y  98                    
SITE     2 DC5  8 ILE Y  99  PHE Y 100  CYS Y 101  CYS Y 104                    
SITE     1 DC6  6 CYS Y  53  ILE Y  54  CYS Y  56  CYS Y  59                    
SITE     2 DC6  6 CYS Y 108  THR Y 110                                          
SITE     1 DC7  9 HIS U 115  ASP U 118  CYS U 119  CYS U 122                    
SITE     2 DC7  9 CYS U 128  LEU U 130  GLN U 131  VAL U 232                    
SITE     3 DC7  9 GLY U 233                                                     
SITE     1 DC8  6 CYS U 181  ILE U 182  CYS U 184  CYS U 187                    
SITE     2 DC8  6 CYS U 230  LEU U 235                                          
SITE     1 DC9  9 CYS U 256  LEU U 258  CYS U 259  VAL U 261                    
SITE     2 DC9  9 GLY U 262  CYS U 263  ILE U 290  CYS U 291                    
SITE     3 DC9  9 PRO U 407                                                     
SITE     1 EC1  7 CYS U  34  SER U  35  GLY U  43  ALA U  44                    
SITE     2 EC1  7 CYS U  45  CYS U  48  CYS U  83                               
SITE     1 EC2 10 PRO S 199  SER S 352  CYS S 353  GLY S 354                    
SITE     2 EC2 10 LYS S 355  CYS S 356  CYS S 359  PHE S 399                    
SITE     3 EC2 10 CYS S 400  ALA S 403                                          
SITE     1 EC3  8 CYS T  83  SER T  87  CYS T  88  CYS T 124                    
SITE     2 EC3  8 LEU T 125  GLY T 126  SER T 127  CYS T 128                    
SITE     1 EC4 14 GLY S  64  GLY S  66  THR S  72  LYS S  75                    
SITE     2 EC4 14 ASN S  92  ASP S  94  GLU S  95  SER S  96                    
SITE     3 EC4 14 GLU S  97  GLY S 183  ILE S 218  ASN S 219                    
SITE     4 EC4 14 ASN S 220  THR S 223                                          
CRYST1  135.080  266.112  201.731  90.00 104.71  90.00 P 1 21 1      8          
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      0.007403  0.000000  0.001944        0.00000                         
SCALE2      0.000000  0.003758  0.000000        0.00000                         
SCALE3      0.000000  0.000000  0.005125        0.00000                         
(ATOM LINES ARE NOT SHOWN.)
END                                                                             
DBGET integrated database retrieval system