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Database: PDB
Entry: 2YTU
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Original site: 2YTU 
HEADER    SIGNALING PROTEIN                       05-APR-07   2YTU              
TITLE     SOLUTION STRUCTURE OF THE SAM_PNT-DOMAIN OF THE HUMAN                 
TITLE    2 FRIEND LEUKEMIAINTEGRATION 1 TRANSCRIPTION FACTOR                    
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: FRIEND LEUKEMIA INTEGRATION 1 TRANSCRIPTION                
COMPND   3 FACTOR;                                                              
COMPND   4 CHAIN: A;                                                            
COMPND   5 FRAGMENT: SAM_PNT DOMAIN;                                            
COMPND   6 SYNONYM: FLI-1 PROTO- ONCOGENE, ERGB TRANSCRIPTION FACTOR;           
COMPND   7 ENGINEERED: YES                                                      
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE   3 ORGANISM_COMMON: HUMAN;                                              
SOURCE   4 ORGANISM_TAXID: 9606;                                                
SOURCE   5 GENE: FLI1;                                                          
SOURCE   6 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                              
SOURCE   7 EXPRESSION_SYSTEM_PLASMID: P061225-64;                               
SOURCE   8 OTHER_DETAILS: CELL-FREE PROTEIN SYNTHESIS                           
KEYWDS    CELL-FREE PROTEIN SYNTHESIS, PROTEIN REGULATION, STRUCTURAL           
KEYWDS   2 GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL             
KEYWDS   3 AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL                            
KEYWDS   4 GENOMICS/PROTEOMICS INITIATIVE, RSGI, SIGNALING PROTEIN              
EXPDTA    SOLUTION NMR                                                          
NUMMDL    20                                                                    
AUTHOR    A.K.GORONCY,M.SATO,N.TOCHIO,S.KOSHIBA,S.WATANABE,T.HARADA,            
AUTHOR   2 T.KIGAWA,S.YOKOYAMA,RIKEN STRUCTURAL GENOMICS/PROTEOMICS             
AUTHOR   3 INITIATIVE (RSGI)                                                    
REVDAT   2   24-FEB-09 2YTU    1       VERSN                                    
REVDAT   1   08-APR-08 2YTU    0                                                
JRNL        AUTH   A.K.GORONCY,M.SATO,N.TOCHIO,S.KOSHIBA,S.WATANABE,            
JRNL        AUTH 2 T.HARADA,T.KIGAWA,S.YOKOYAMA                                 
JRNL        TITL   SOLUTION STRUCTURE OF THE SAM_PNT-DOMAIN OF THE              
JRNL        TITL 2 HUMAN FRIEND LEUKEMIAINTEGRATION 1 TRANSCRIPTION             
JRNL        TITL 3 FACTOR                                                       
JRNL        REF    TO BE PUBLISHED                                              
JRNL        REFN                                                                
REMARK   1                                                                      
REMARK   2                                                                      
REMARK   2 RESOLUTION. NOT APPLICABLE.                                          
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   PROGRAM     : CYANA 2.2.2                                          
REMARK   3   AUTHORS     : P.GUNTERT ET AL.                                     
REMARK   3                                                                      
REMARK   3  OTHER REFINEMENT REMARKS: NULL                                      
REMARK   4                                                                      
REMARK   4 2YTU COMPLIES WITH FORMAT V. 3.15, 01-DEC-08                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBJ ON 26-JUN-07.                  
REMARK 100 THE RCSB ID CODE IS RCSB027126.                                      
REMARK 210                                                                      
REMARK 210 EXPERIMENTAL DETAILS                                                 
REMARK 210  EXPERIMENT TYPE                : NMR                                
REMARK 210  TEMPERATURE           (KELVIN) : 296                                
REMARK 210  PH                             : 7.0                                
REMARK 210  IONIC STRENGTH                 : 120 MM                             
REMARK 210  PRESSURE                       : AMBIENT                            
REMARK 210  SAMPLE CONTENTS                : 0.24MM SAM_PNT DOMAIN, 20MM D      
REMARK 210                                   -TRIS-HCL, 100MM NACL, 1MM D-      
REMARK 210                                   DTT, 0.02% NAN3, 90% H2O, 10%      
REMARK 210                                   D2O                                
REMARK 210                                                                      
REMARK 210  NMR EXPERIMENTS CONDUCTED      : 3D_15N-SEPARATED_NOESY, 3D_        
REMARK 210                                   13C-SEPARATED_NOESY                
REMARK 210  SPECTROMETER FIELD STRENGTH    : 800 MHZ                            
REMARK 210  SPECTROMETER MODEL             : AVANCE                             
REMARK 210  SPECTROMETER MANUFACTURER      : BRUKER                             
REMARK 210                                                                      
REMARK 210  STRUCTURE DETERMINATION.                                            
REMARK 210   SOFTWARE USED                 : CYANA 2.2.2, XWINNMR 3.5,          
REMARK 210                                   NMRPIPE 20060702, NMRVIEW          
REMARK 210                                   5.0.4, KUJIRA 0.9821               
REMARK 210   METHOD USED                   : TORSION ANGLE DYNAMICS             
REMARK 210                                                                      
REMARK 210 CONFORMERS, NUMBER CALCULATED   : 100                                
REMARK 210 CONFORMERS, NUMBER SUBMITTED    : 20                                 
REMARK 210 CONFORMERS, SELECTION CRITERIA  : STRUCTURES WITH THE LEAST          
REMARK 210                                   RESTRAINT VIOLATIONS               
REMARK 210                                                                      
REMARK 210 BEST REPRESENTATIVE CONFORMER IN THIS ENSEMBLE : 1                   
REMARK 210                                                                      
REMARK 210 REMARK: NULL                                                         
REMARK 215                                                                      
REMARK 215 NMR STUDY                                                            
REMARK 215 THE COORDINATES IN THIS ENTRY WERE GENERATED FROM SOLUTION           
REMARK 215 NMR DATA.  PROTEIN DATA BANK CONVENTIONS REQUIRE THAT                
REMARK 215 CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES ON              
REMARK 215 THESE RECORDS ARE MEANINGLESS.                                       
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: TORSION ANGLES                                             
REMARK 500                                                                      
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:            
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)                    
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-           
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400            
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        PSI       PHI                                   
REMARK 500  1 TYR A  10       89.42     60.68                                   
REMARK 500  1 PRO A  23     -173.43    -69.78                                   
REMARK 500  1 MET A  25      142.04   -172.19                                   
REMARK 500  1 THR A  27      -69.04   -122.10                                   
REMARK 500  1 GLU A  29       74.53   -156.38                                   
REMARK 500  1 ALA A  36      -75.21   -178.25                                   
REMARK 500  1 LEU A  40       50.55   -106.43                                   
REMARK 500  1 GLU A  61       81.15     62.56                                   
REMARK 500  1 ASN A  69       46.56   -161.00                                   
REMARK 500  1 TYR A 110       93.45    -65.95                                   
REMARK 500  1 THR A 113       98.50     62.40                                   
REMARK 500  1 ARG A 121       54.50   -143.85                                   
REMARK 500  1 ASP A 127      160.61     63.21                                   
REMARK 500  2 SER A   3      162.52     63.14                                   
REMARK 500  2 SER A   5      177.66     58.50                                   
REMARK 500  2 SER A   6      -73.88    -91.66                                   
REMARK 500  2 ASN A   9      170.66     62.37                                   
REMARK 500  2 SER A  12       79.65   -155.78                                   
REMARK 500  2 ASN A  24       94.12     59.22                                   
REMARK 500  2 MET A  25     -173.72   -171.87                                   
REMARK 500  2 THR A  27       76.02     56.32                                   
REMARK 500  2 GLU A  29       74.62     52.64                                   
REMARK 500  2 ARG A  30       48.32   -155.52                                   
REMARK 500  2 ARG A  31      -66.57    -95.78                                   
REMARK 500  2 VAL A  32      139.06   -173.09                                   
REMARK 500  2 ALA A  36      -73.57   -178.22                                   
REMARK 500  2 LEU A  40       46.52   -102.67                                   
REMARK 500  2 GLU A  61       94.08     58.25                                   
REMARK 500  2 ASN A  69       46.06   -155.65                                   
REMARK 500  2 SER A 114     -170.28     52.51                                   
REMARK 500  2 HIS A 115      -67.82   -130.54                                   
REMARK 500  2 ASP A 117       36.46   -157.85                                   
REMARK 500  2 GLN A 118      -73.99   -116.56                                   
REMARK 500  2 SER A 119     -177.45     63.16                                   
REMARK 500  2 LEU A 122     -178.93     58.38                                   
REMARK 500  2 LYS A 125      178.19     59.79                                   
REMARK 500  2 GLU A 126      -53.96   -137.67                                   
REMARK 500  3 SER A   2       38.05   -161.29                                   
REMARK 500  3 ASN A  24      -63.20   -170.94                                   
REMARK 500  3 THR A  27       95.16     58.02                                   
REMARK 500  3 ASN A  28     -171.55     62.16                                   
REMARK 500  3 ARG A  30     -176.26     58.01                                   
REMARK 500  3 ALA A  36      -63.78   -177.86                                   
REMARK 500  3 LEU A  40       46.04   -104.13                                   
REMARK 500  3 GLU A  61       92.31     57.84                                   
REMARK 500  3 SER A 114      102.15   -174.01                                   
REMARK 500  3 SER A 120      -71.44   -154.84                                   
REMARK 500  3 ARG A 121      169.63     63.05                                   
REMARK 500  3 LEU A 122       94.70   -165.64                                   
REMARK 500  4 SER A  12       73.42   -150.46                                   
REMARK 500  4 ASN A  24      -57.07   -157.27                                   
REMARK 500  4 THR A  27       73.54   -160.83                                   
REMARK 500  4 ASN A  28      -50.10   -141.94                                   
REMARK 500  4 VAL A  32      132.99   -175.35                                   
REMARK 500  4 ALA A  36      -66.32   -178.38                                   
REMARK 500  4 LEU A  40       42.04    -99.64                                   
REMARK 500  4 SER A  58       60.38     63.10                                   
REMARK 500  4 GLU A  61       89.99     61.69                                   
REMARK 500  4 ASN A  69       44.93   -161.08                                   
REMARK 500  4 THR A 112      177.76     59.03                                   
REMARK 500  4 HIS A 115       90.06   -169.10                                   
REMARK 500  4 ASP A 127       70.06     54.47                                   
REMARK 500  5 SER A   3     -178.63     61.20                                   
REMARK 500  5 SER A  12       58.23   -147.27                                   
REMARK 500  5 ASP A  15      114.91   -173.85                                   
REMARK 500  5 MET A  25     -175.93     61.67                                   
REMARK 500  5 THR A  27      -73.37    -81.61                                   
REMARK 500  5 GLU A  29       81.17   -172.69                                   
REMARK 500  5 ARG A  31       28.20   -151.69                                   
REMARK 500  5 VAL A  32      137.35   -173.94                                   
REMARK 500  5 ALA A  36      -72.55   -178.25                                   
REMARK 500  5 LEU A  40       48.19   -106.65                                   
REMARK 500  5 GLU A  61       81.58     59.39                                   
REMARK 500  5 GLN A  68      -73.35    -58.15                                   
REMARK 500  5 TYR A 110      101.66    -57.94                                   
REMARK 500  5 ASN A 111       52.09   -146.42                                   
REMARK 500  5 THR A 113      -48.02   -163.74                                   
REMARK 500  5 ASP A 117       74.22   -117.87                                   
REMARK 500  5 GLN A 118       67.67   -113.77                                   
REMARK 500  6 PRO A  23     -175.05    -69.76                                   
REMARK 500  6 MET A  25      -68.52   -166.19                                   
REMARK 500  6 THR A  26       38.29   -142.73                                   
REMARK 500  6 ASN A  28      -62.08   -155.35                                   
REMARK 500  6 ARG A  30       83.64     55.84                                   
REMARK 500  6 ARG A  31      -73.01   -148.52                                   
REMARK 500  6 VAL A  32      126.42   -173.75                                   
REMARK 500  6 ALA A  36      -74.93   -178.30                                   
REMARK 500  6 LEU A  40       49.14   -101.48                                   
REMARK 500  6 LEU A  59     -170.98    -68.69                                   
REMARK 500  6 GLU A  61       93.85     62.30                                   
REMARK 500  6 ASN A  69       55.44   -156.90                                   
REMARK 500  6 THR A 112      170.02     64.24                                   
REMARK 500  6 HIS A 115     -174.71    -63.59                                   
REMARK 500  7 SER A   2       87.15     56.68                                   
REMARK 500  7 SER A   5       88.80   -156.36                                   
REMARK 500  7 THR A  27      178.60    -57.08                                   
REMARK 500  7 GLU A  29       72.76   -106.70                                   
REMARK 500  7 ARG A  30       95.01   -170.54                                   
REMARK 500  7 ALA A  36      -74.00   -178.26                                   
REMARK 500  7 LEU A  40       52.42   -102.87                                   
REMARK 500  7 GLN A  68      -74.02    -71.33                                   
REMARK 500  7 ALA A 109       33.02    -96.33                                   
REMARK 500  7 THR A 113      173.92     63.84                                   
REMARK 500  7 THR A 116       37.87   -151.08                                   
REMARK 500  8 MET A   8      -74.32    -80.72                                   
REMARK 500  8 ASN A   9       49.95   -175.09                                   
REMARK 500  8 ARG A  30       80.57     52.80                                   
REMARK 500  8 ARG A  31       27.21   -152.30                                   
REMARK 500  8 VAL A  32      140.60   -175.74                                   
REMARK 500  8 ALA A  36      -70.49   -178.35                                   
REMARK 500  8 LEU A  40       53.80   -103.24                                   
REMARK 500  8 SER A  58       63.35     63.02                                   
REMARK 500  8 GLU A  61       95.31     58.64                                   
REMARK 500  8 GLN A  68      -73.05    -59.74                                   
REMARK 500  8 THR A 112       94.00    -63.73                                   
REMARK 500  8 THR A 116       32.83   -140.46                                   
REMARK 500  8 ASP A 117      176.33     59.99                                   
REMARK 500  8 SER A 123       76.90   -113.49                                   
REMARK 500  9 SER A   3      171.54     61.01                                   
REMARK 500  9 SER A   5      112.32   -171.78                                   
REMARK 500  9 ASN A   9      103.80   -162.42                                   
REMARK 500  9 ASN A  28     -171.00     57.67                                   
REMARK 500  9 GLU A  29      114.82   -162.02                                   
REMARK 500  9 ARG A  30       43.45   -141.94                                   
REMARK 500  9 ALA A  36      -75.44   -178.29                                   
REMARK 500  9 LEU A  40       53.17   -105.13                                   
REMARK 500  9 GLU A  61       94.37     60.97                                   
REMARK 500  9 ASN A  69       35.85   -155.75                                   
REMARK 500  9 TYR A 110       98.55    -60.69                                   
REMARK 500  9 ASN A 111      -69.26   -125.43                                   
REMARK 500  9 SER A 123       57.27   -162.33                                   
REMARK 500 10 SER A   2      124.73   -176.40                                   
REMARK 500 10 ASN A   9      -62.28   -120.44                                   
REMARK 500 10 TYR A  10       86.33     56.23                                   
REMARK 500 10 GLU A  16      115.49   -179.10                                   
REMARK 500 10 MET A  25       57.79   -161.98                                   
REMARK 500 10 THR A  27      -73.15   -136.95                                   
REMARK 500 10 VAL A  32      126.71   -171.90                                   
REMARK 500 10 ALA A  36      -75.10   -178.38                                   
REMARK 500 10 LEU A  40       28.62   -150.75                                   
REMARK 500 10 GLU A  61       82.59     60.32                                   
REMARK 500 10 THR A 112      110.10     64.60                                   
REMARK 500 10 LEU A 122      178.14     58.42                                   
REMARK 500 11 ASN A   9      -66.13   -130.60                                   
REMARK 500 11 TYR A  10     -170.37     63.05                                   
REMARK 500 11 SER A  12      111.71   -160.84                                   
REMARK 500 11 MET A  25     -169.99    -73.36                                   
REMARK 500 11 ASN A  28      161.44     63.26                                   
REMARK 500 11 ARG A  31      -73.96    -54.77                                   
REMARK 500 11 VAL A  32      129.00   -177.35                                   
REMARK 500 11 ALA A  36      -75.35   -178.29                                   
REMARK 500 11 LEU A  40       50.87   -107.25                                   
REMARK 500 11 GLU A  61       94.10     59.08                                   
REMARK 500 11 ASN A  69       41.11   -155.48                                   
REMARK 500 11 SER A 114       92.54     57.41                                   
REMARK 500 11 SER A 120       41.88   -168.79                                   
REMARK 500 11 ASP A 127       70.11   -152.49                                   
REMARK 500 12 SER A   3     -175.25     60.45                                   
REMARK 500 12 ASN A  11      173.95     60.48                                   
REMARK 500 12 MET A  25     -178.47     61.25                                   
REMARK 500 12 ARG A  31      -70.01    -68.80                                   
REMARK 500 12 ALA A  36      -72.10   -178.26                                   
REMARK 500 12 LEU A  40       56.56   -105.86                                   
REMARK 500 12 GLU A  61       85.64     63.18                                   
REMARK 500 12 ASN A  69       26.94   -152.00                                   
REMARK 500 12 ASN A 111       82.56     53.15                                   
REMARK 500 12 ASP A 117       55.40   -168.34                                   
REMARK 500 12 SER A 120     -179.70     57.93                                   
REMARK 500 12 VAL A 124       76.77     52.47                                   
REMARK 500 13 MET A   8      119.85   -172.28                                   
REMARK 500 13 TYR A  10      132.72   -173.75                                   
REMARK 500 13 ASN A  11      143.83   -178.23                                   
REMARK 500 13 LYS A  17       89.89   -163.07                                   
REMARK 500 13 THR A  27       43.43   -155.16                                   
REMARK 500 13 ARG A  31      107.48   -166.42                                   
REMARK 500 13 ALA A  36      -75.51   -178.21                                   
REMARK 500 13 LEU A  40       53.37   -101.51                                   
REMARK 500 13 GLU A  61       67.62     63.22                                   
REMARK 500 13 ASN A  69       49.34   -158.06                                   
REMARK 500 13 SER A 114     -172.83     62.60                                   
REMARK 500 13 HIS A 115     -176.41   -174.72                                   
REMARK 500 13 SER A 120       84.11   -159.05                                   
REMARK 500 13 GLU A 126      -49.61   -137.36                                   
REMARK 500 14 SER A  12       90.16     54.80                                   
REMARK 500 14 ASN A  18       78.37     58.43                                   
REMARK 500 14 THR A  26     -171.07     51.39                                   
REMARK 500 14 THR A  27       38.87    -96.59                                   
REMARK 500 14 ARG A  30       85.61     53.03                                   
REMARK 500 14 VAL A  32      136.89   -172.41                                   
REMARK 500 14 ALA A  36      -73.05   -178.23                                   
REMARK 500 14 LEU A  40       49.71   -107.69                                   
REMARK 500 14 GLU A  61       97.31     63.05                                   
REMARK 500 14 ASN A  69       56.10   -155.35                                   
REMARK 500 14 THR A 112      162.29     63.07                                   
REMARK 500 14 SER A 120       80.45     59.19                                   
REMARK 500 14 SER A 123      177.84     62.07                                   
REMARK 500 15 ASN A  18       93.23     57.35                                   
REMARK 500 15 MET A  25       89.94     55.84                                   
REMARK 500 15 ASN A  28      -63.91    -97.20                                   
REMARK 500 15 ARG A  30      106.28   -172.44                                   
REMARK 500 15 ARG A  31      -70.08   -120.28                                   
REMARK 500 15 VAL A  32      129.22   -176.33                                   
REMARK 500 15 ALA A  36      -71.19   -178.25                                   
REMARK 500 15 LEU A  40       52.39   -104.63                                   
REMARK 500 15 SER A  58       73.00     63.16                                   
REMARK 500 15 GLU A  61       68.71   -118.67                                   
REMARK 500 15 ASN A 111      102.71     62.70                                   
REMARK 500 15 SER A 119       42.30   -149.41                                   
REMARK 500 15 LEU A 122      177.00     62.27                                   
REMARK 500 16 SER A   2      103.54   -162.00                                   
REMARK 500 16 SER A   3       89.29   -153.18                                   
REMARK 500 16 ASN A  11     -170.63     61.09                                   
REMARK 500 16 MET A  14      173.75    -59.19                                   
REMARK 500 16 GLU A  16       91.54     63.21                                   
REMARK 500 16 ASN A  24      100.54     61.47                                   
REMARK 500 16 MET A  25     -177.88     59.65                                   
REMARK 500 16 THR A  26      -37.86   -177.13                                   
REMARK 500 16 ALA A  36      -75.01   -178.23                                   
REMARK 500 16 LEU A  40       50.56   -101.41                                   
REMARK 500 16 SER A  58       61.65     63.08                                   
REMARK 500 16 GLU A  61       93.35     58.57                                   
REMARK 500 16 ASN A  69       43.77   -157.83                                   
REMARK 500 16 TYR A 110     -173.45    -60.22                                   
REMARK 500 16 THR A 112     -173.63     56.22                                   
REMARK 500 16 SER A 120      -58.48   -132.01                                   
REMARK 500 16 SER A 123       85.54     55.67                                   
REMARK 500 16 LYS A 125       27.38   -157.02                                   
REMARK 500 16 GLU A 126       72.89     52.19                                   
REMARK 500 17 SER A   2       75.76     56.70                                   
REMARK 500 17 SER A   5     -178.32     62.71                                   
REMARK 500 17 ASP A  15       41.75   -172.47                                   
REMARK 500 17 LYS A  17       43.16   -158.53                                   
REMARK 500 17 THR A  26       97.76     58.72                                   
REMARK 500 17 GLU A  29       50.43   -156.79                                   
REMARK 500 17 ARG A  30       59.14   -156.50                                   
REMARK 500 17 ARG A  31      -61.67   -137.53                                   
REMARK 500 17 ALA A  36      -72.95   -178.40                                   
REMARK 500 17 LEU A  40       43.91    -96.69                                   
REMARK 500 17 ASN A  69       37.81   -161.12                                   
REMARK 500 17 TYR A 110       96.80    -67.73                                   
REMARK 500 17 ASN A 111      -43.84   -148.72                                   
REMARK 500 17 THR A 112      166.02     62.02                                   
REMARK 500 17 ARG A 121       42.59   -171.93                                   
REMARK 500 18 SER A   2       37.29   -177.07                                   
REMARK 500 18 ASP A  15      140.91   -171.05                                   
REMARK 500 18 GLU A  16      -70.28   -139.68                                   
REMARK 500 18 ASN A  18      108.67   -175.89                                   
REMARK 500 18 ASN A  28     -170.63     58.80                                   
REMARK 500 18 ARG A  30      177.42     62.10                                   
REMARK 500 18 ARG A  31      -68.38   -100.05                                   
REMARK 500 18 VAL A  32      132.52   -176.47                                   
REMARK 500 18 ALA A  36      -75.04   -177.04                                   
REMARK 500 18 THR A  39       30.53    -95.50                                   
REMARK 500 18 LEU A  40       25.90   -149.41                                   
REMARK 500 18 GLU A  61       97.33     62.48                                   
REMARK 500 18 ASN A  69       74.90   -168.89                                   
REMARK 500 18 ASN A 111      170.26     62.33                                   
REMARK 500 18 GLN A 118       99.27    -61.16                                   
REMARK 500 18 SER A 120       91.95    -67.04                                   
REMARK 500 19 ASN A   9      -42.25   -166.37                                   
REMARK 500 19 TYR A  10      167.36     63.13                                   
REMARK 500 19 THR A  26       97.11     58.28                                   
REMARK 500 19 GLU A  29      106.26   -166.02                                   
REMARK 500 19 VAL A  32      124.25   -177.37                                   
REMARK 500 19 ALA A  36      -72.81   -178.34                                   
REMARK 500 19 LEU A  40       50.71   -101.07                                   
REMARK 500 19 SER A  58       63.27     63.17                                   
REMARK 500 19 GLU A  61       82.54     61.96                                   
REMARK 500 19 ASN A  69       67.31   -154.15                                   
REMARK 500 19 ASN A 111     -171.71     62.01                                   
REMARK 500 19 SER A 114       96.88     61.43                                   
REMARK 500 19 LEU A 122       88.16     62.15                                   
REMARK 500 19 GLU A 126      116.90   -173.61                                   
REMARK 500 20 SER A   6      116.59   -172.05                                   
REMARK 500 20 TYR A  10      176.02     62.61                                   
REMARK 500 20 ASN A  11      -50.48   -139.55                                   
REMARK 500 20 SER A  12      160.80     63.26                                   
REMARK 500 20 ASN A  24      144.07   -172.85                                   
REMARK 500 20 ASN A  28     -177.69     61.27                                   
REMARK 500 20 ARG A  31       77.81     59.50                                   
REMARK 500 20 ALA A  36      -68.12   -178.16                                   
REMARK 500 20 LEU A  40       49.10   -106.55                                   
REMARK 500 20 GLU A  61       89.98     58.22                                   
REMARK 500 20 ASN A  69       26.37   -148.88                                   
REMARK 500 20 TYR A 110     -175.83    -59.67                                   
REMARK 500 20 ASN A 111       97.09     60.79                                   
REMARK 500 20 THR A 112      179.98    -57.21                                   
REMARK 500 20 VAL A 124       80.57     60.90                                   
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 900                                                                      
REMARK 900 RELATED ENTRIES                                                      
REMARK 900 RELATED ID: HSI002003894.2   RELATED DB: TARGETDB                    
DBREF  2YTU A    8   128  UNP    Q01543   FLI1_HUMAN     100    220             
SEQADV 2YTU GLY A    1  UNP  Q01543              EXPRESSION TAG                 
SEQADV 2YTU SER A    2  UNP  Q01543              EXPRESSION TAG                 
SEQADV 2YTU SER A    3  UNP  Q01543              EXPRESSION TAG                 
SEQADV 2YTU GLY A    4  UNP  Q01543              EXPRESSION TAG                 
SEQADV 2YTU SER A    5  UNP  Q01543              EXPRESSION TAG                 
SEQADV 2YTU SER A    6  UNP  Q01543              EXPRESSION TAG                 
SEQADV 2YTU GLY A    7  UNP  Q01543              EXPRESSION TAG                 
SEQRES   1 A  128  GLY SER SER GLY SER SER GLY MET ASN TYR ASN SER TYR          
SEQRES   2 A  128  MET ASP GLU LYS ASN GLY PRO PRO PRO PRO ASN MET THR          
SEQRES   3 A  128  THR ASN GLU ARG ARG VAL ILE VAL PRO ALA ASP PRO THR          
SEQRES   4 A  128  LEU TRP THR GLN GLU HIS VAL ARG GLN TRP LEU GLU TRP          
SEQRES   5 A  128  ALA ILE LYS GLU TYR SER LEU MET GLU ILE ASP THR SER          
SEQRES   6 A  128  PHE PHE GLN ASN MET ASP GLY LYS GLU LEU CYS LYS MET          
SEQRES   7 A  128  ASN LYS GLU ASP PHE LEU ARG ALA THR THR LEU TYR ASN          
SEQRES   8 A  128  THR GLU VAL LEU LEU SER HIS LEU SER TYR LEU ARG GLU          
SEQRES   9 A  128  SER SER LEU LEU ALA TYR ASN THR THR SER HIS THR ASP          
SEQRES  10 A  128  GLN SER SER ARG LEU SER VAL LYS GLU ASP PRO                  
HELIX    1   1 ASP A   37  TRP A   41  5                                   5    
HELIX    2   2 GLU A   44  TYR A   57  1                                  14    
HELIX    3   3 THR A   64  GLN A   68  5                                   5    
HELIX    4   4 LYS A   73  MET A   78  1                                   6    
HELIX    5   5 ASN A   79  THR A   87  1                                   9    
HELIX    6   6 THR A   88  TYR A  110  1                                  23    
CISPEP   1 PRO A   21    PRO A   22          1        -0.10                     
CISPEP   2 PRO A   21    PRO A   22          2        -0.08                     
CISPEP   3 PRO A   21    PRO A   22          3        -0.01                     
CISPEP   4 PRO A   21    PRO A   22          4         0.02                     
CISPEP   5 PRO A   21    PRO A   22          5        -0.03                     
CISPEP   6 PRO A   21    PRO A   22          6        -0.04                     
CISPEP   7 PRO A   21    PRO A   22          7        -0.09                     
CISPEP   8 PRO A   21    PRO A   22          8        -0.04                     
CISPEP   9 PRO A   21    PRO A   22          9        -0.12                     
CISPEP  10 PRO A   21    PRO A   22         10        -0.04                     
CISPEP  11 PRO A   21    PRO A   22         11        -0.05                     
CISPEP  12 PRO A   21    PRO A   22         12        -0.06                     
CISPEP  13 PRO A   21    PRO A   22         13        -0.06                     
CISPEP  14 PRO A   21    PRO A   22         14        -0.04                     
CISPEP  15 PRO A   21    PRO A   22         15        -0.05                     
CISPEP  16 PRO A   21    PRO A   22         16        -0.04                     
CISPEP  17 PRO A   21    PRO A   22         17        -0.05                     
CISPEP  18 PRO A   21    PRO A   22         18        -0.02                     
CISPEP  19 PRO A   21    PRO A   22         19        -0.02                     
CISPEP  20 PRO A   21    PRO A   22         20         0.02                     
CRYST1    1.000    1.000    1.000  90.00  90.00  90.00 P 1           1          
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      1.000000  0.000000  0.000000        0.00000                         
SCALE2      0.000000  1.000000  0.000000        0.00000                         
SCALE3      0.000000  0.000000  1.000000        0.00000                         
MODEL        1                                                                  
(ATOM LINES ARE NOT SHOWN.)
END                                                                             
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