HEADER RIBOSOME/INHIBITOR 03-JUN-14 3J7A
TITLE CRYO-EM STRUCTURE OF THE PLASMODIUM FALCIPARUM 80S RIBOSOME BOUND TO
TITLE 2 THE ANTI-PROTOZOAN DRUG EMETINE, SMALL SUBUNIT
COMPND MOL_ID: 1;
COMPND 2 MOLECULE: 18S RIBOSOMAL RNA;
COMPND 3 CHAIN: A;
COMPND 4 MOL_ID: 2;
COMPND 5 MOLECULE: 40S RIBOSOMAL PROTEIN ES1;
COMPND 6 CHAIN: B;
COMPND 7 MOL_ID: 3;
COMPND 8 MOLECULE: 40S RIBOSOMAL PROTEIN US2;
COMPND 9 CHAIN: C;
COMPND 10 MOL_ID: 4;
COMPND 11 MOLECULE: 40S RIBOSOMAL PROTEIN US3;
COMPND 12 CHAIN: D;
COMPND 13 MOL_ID: 5;
COMPND 14 MOLECULE: 40S RIBOSOMAL PROTEIN US4;
COMPND 15 CHAIN: E;
COMPND 16 MOL_ID: 6;
COMPND 17 MOLECULE: 40S RIBOSOMAL PROTEIN ES4;
COMPND 18 CHAIN: F;
COMPND 19 MOL_ID: 7;
COMPND 20 MOLECULE: 40S RIBOSOMAL PROTEIN US5;
COMPND 21 CHAIN: G;
COMPND 22 MOL_ID: 8;
COMPND 23 MOLECULE: 40S RIBOSOMAL PROTEIN ES6;
COMPND 24 CHAIN: H;
COMPND 25 MOL_ID: 9;
COMPND 26 MOLECULE: 40S RIBOSOMAL PROTEIN US7;
COMPND 27 CHAIN: I;
COMPND 28 MOL_ID: 10;
COMPND 29 MOLECULE: 40S RIBOSOMAL PROTEIN ES7;
COMPND 30 CHAIN: J;
COMPND 31 MOL_ID: 11;
COMPND 32 MOLECULE: 40S RIBOSOMAL PROTEIN US8;
COMPND 33 CHAIN: K;
COMPND 34 MOL_ID: 12;
COMPND 35 MOLECULE: 40S RIBOSOMAL PROTEIN ES8;
COMPND 36 CHAIN: L;
COMPND 37 MOL_ID: 13;
COMPND 38 MOLECULE: 40S RIBOSOMAL PROTEIN US9;
COMPND 39 CHAIN: M;
COMPND 40 MOL_ID: 14;
COMPND 41 MOLECULE: 40S RIBOSOMAL PROTEIN US10;
COMPND 42 CHAIN: N;
COMPND 43 MOL_ID: 15;
COMPND 44 MOLECULE: 40S RIBOSOMAL PROTEIN ES10;
COMPND 45 CHAIN: O;
COMPND 46 MOL_ID: 16;
COMPND 47 MOLECULE: 40S RIBOSOMAL PROTEIN US11;
COMPND 48 CHAIN: P;
COMPND 49 MOL_ID: 17;
COMPND 50 MOLECULE: 40S RIBOSOMAL PROTEIN US12;
COMPND 51 CHAIN: Q;
COMPND 52 MOL_ID: 18;
COMPND 53 MOLECULE: 40S RIBOSOMAL PROTEIN ES12;
COMPND 54 CHAIN: R;
COMPND 55 MOL_ID: 19;
COMPND 56 MOLECULE: 40S RIBOSOMAL PROTEIN US13;
COMPND 57 CHAIN: S;
COMPND 58 MOL_ID: 20;
COMPND 59 MOLECULE: 40S RIBOSOMAL PROTEIN US14;
COMPND 60 CHAIN: T;
COMPND 61 MOL_ID: 21;
COMPND 62 MOLECULE: 40S RIBOSOMAL PROTEIN US15;
COMPND 63 CHAIN: U;
COMPND 64 MOL_ID: 22;
COMPND 65 MOLECULE: 40S RIBOSOMAL PROTEIN US17;
COMPND 66 CHAIN: V;
COMPND 67 MOL_ID: 23;
COMPND 68 MOLECULE: 40S RIBOSOMAL PROTEIN ES17;
COMPND 69 CHAIN: W;
COMPND 70 MOL_ID: 24;
COMPND 71 MOLECULE: 40S RIBOSOMAL PROTEIN US19;
COMPND 72 CHAIN: X;
COMPND 73 MOL_ID: 25;
COMPND 74 MOLECULE: 40S RIBOSOMAL PROTEIN ES19;
COMPND 75 CHAIN: Y;
COMPND 76 MOL_ID: 26;
COMPND 77 MOLECULE: 40S RIBOSOMAL PROTEIN ES21;
COMPND 78 CHAIN: Z;
COMPND 79 MOL_ID: 27;
COMPND 80 MOLECULE: 40S RIBOSOMAL PROTEIN ES24;
COMPND 81 CHAIN: 1;
COMPND 82 MOL_ID: 28;
COMPND 83 MOLECULE: 40S RIBOSOMAL PROTEIN ES25;
COMPND 84 CHAIN: 2;
COMPND 85 MOL_ID: 29;
COMPND 86 MOLECULE: 40S RIBOSOMAL PROTEIN ES26;
COMPND 87 CHAIN: 3;
COMPND 88 MOL_ID: 30;
COMPND 89 MOLECULE: 40S RIBOSOMAL PROTEIN ES27;
COMPND 90 CHAIN: 4;
COMPND 91 MOL_ID: 31;
COMPND 92 MOLECULE: 40S RIBOSOMAL PROTEIN ES28;
COMPND 93 CHAIN: 5;
COMPND 94 MOL_ID: 32;
COMPND 95 MOLECULE: 40S RIBOSOMAL PROTEIN ES30;
COMPND 96 CHAIN: 6;
COMPND 97 MOL_ID: 33;
COMPND 98 MOLECULE: TRNA;
COMPND 99 CHAIN: 7
SOURCE MOL_ID: 1;
SOURCE 2 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 3 ORGANISM_TAXID: 36329;
SOURCE 4 STRAIN: 3D7;
SOURCE 5 MOL_ID: 2;
SOURCE 6 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 7 ORGANISM_TAXID: 36329;
SOURCE 8 STRAIN: 3D7;
SOURCE 9 MOL_ID: 3;
SOURCE 10 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 11 ORGANISM_TAXID: 36329;
SOURCE 12 STRAIN: 3D7;
SOURCE 13 MOL_ID: 4;
SOURCE 14 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 15 ORGANISM_TAXID: 36329;
SOURCE 16 STRAIN: 3D7;
SOURCE 17 MOL_ID: 5;
SOURCE 18 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 19 ORGANISM_TAXID: 36329;
SOURCE 20 STRAIN: 3D7;
SOURCE 21 MOL_ID: 6;
SOURCE 22 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 23 ORGANISM_TAXID: 36329;
SOURCE 24 STRAIN: 3D7;
SOURCE 25 MOL_ID: 7;
SOURCE 26 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 27 ORGANISM_TAXID: 36329;
SOURCE 28 STRAIN: 3D7;
SOURCE 29 MOL_ID: 8;
SOURCE 30 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 31 ORGANISM_TAXID: 36329;
SOURCE 32 STRAIN: 3D7;
SOURCE 33 MOL_ID: 9;
SOURCE 34 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 35 ORGANISM_TAXID: 36329;
SOURCE 36 STRAIN: 3D7;
SOURCE 37 MOL_ID: 10;
SOURCE 38 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 39 ORGANISM_TAXID: 36329;
SOURCE 40 STRAIN: 3D7;
SOURCE 41 MOL_ID: 11;
SOURCE 42 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 43 ORGANISM_TAXID: 36329;
SOURCE 44 STRAIN: 3D7;
SOURCE 45 MOL_ID: 12;
SOURCE 46 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 47 ORGANISM_TAXID: 36329;
SOURCE 48 STRAIN: 3D7;
SOURCE 49 MOL_ID: 13;
SOURCE 50 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 51 ORGANISM_TAXID: 36329;
SOURCE 52 STRAIN: 3D7;
SOURCE 53 MOL_ID: 14;
SOURCE 54 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 55 ORGANISM_TAXID: 36329;
SOURCE 56 STRAIN: 3D7;
SOURCE 57 MOL_ID: 15;
SOURCE 58 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 59 ORGANISM_TAXID: 36329;
SOURCE 60 STRAIN: 3D7;
SOURCE 61 MOL_ID: 16;
SOURCE 62 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 63 ORGANISM_TAXID: 36329;
SOURCE 64 STRAIN: 3D7;
SOURCE 65 MOL_ID: 17;
SOURCE 66 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 67 ORGANISM_TAXID: 36329;
SOURCE 68 STRAIN: 3D7;
SOURCE 69 MOL_ID: 18;
SOURCE 70 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 71 ORGANISM_TAXID: 36329;
SOURCE 72 STRAIN: 3D7;
SOURCE 73 MOL_ID: 19;
SOURCE 74 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 75 ORGANISM_TAXID: 36329;
SOURCE 76 STRAIN: 3D7;
SOURCE 77 MOL_ID: 20;
SOURCE 78 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 79 ORGANISM_TAXID: 36329;
SOURCE 80 STRAIN: 3D7;
SOURCE 81 MOL_ID: 21;
SOURCE 82 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 83 ORGANISM_TAXID: 36329;
SOURCE 84 STRAIN: 3D7;
SOURCE 85 MOL_ID: 22;
SOURCE 86 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 87 ORGANISM_TAXID: 36329;
SOURCE 88 STRAIN: 3D7;
SOURCE 89 MOL_ID: 23;
SOURCE 90 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 91 ORGANISM_TAXID: 36329;
SOURCE 92 STRAIN: 3D7;
SOURCE 93 MOL_ID: 24;
SOURCE 94 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 95 ORGANISM_TAXID: 36329;
SOURCE 96 STRAIN: 3D7;
SOURCE 97 MOL_ID: 25;
SOURCE 98 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 99 ORGANISM_TAXID: 36329;
SOURCE 100 STRAIN: 3D7;
SOURCE 101 MOL_ID: 26;
SOURCE 102 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 103 ORGANISM_TAXID: 36329;
SOURCE 104 STRAIN: 3D7;
SOURCE 105 MOL_ID: 27;
SOURCE 106 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 107 ORGANISM_TAXID: 36329;
SOURCE 108 STRAIN: 3D7;
SOURCE 109 MOL_ID: 28;
SOURCE 110 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 111 ORGANISM_TAXID: 36329;
SOURCE 112 STRAIN: 3D7;
SOURCE 113 MOL_ID: 29;
SOURCE 114 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 115 ORGANISM_TAXID: 36329;
SOURCE 116 STRAIN: 3D7;
SOURCE 117 MOL_ID: 30;
SOURCE 118 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 119 ORGANISM_TAXID: 36329;
SOURCE 120 STRAIN: 3D7;
SOURCE 121 MOL_ID: 31;
SOURCE 122 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 123 ORGANISM_TAXID: 36329;
SOURCE 124 STRAIN: 3D7;
SOURCE 125 MOL_ID: 32;
SOURCE 126 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 127 ORGANISM_TAXID: 36329;
SOURCE 128 STRAIN: 3D7;
SOURCE 129 MOL_ID: 33;
SOURCE 130 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM;
SOURCE 131 ORGANISM_TAXID: 36329;
SOURCE 132 STRAIN: 3D7
KEYWDS EMETINE, RIBOSOME-INHIBITOR COMPLEX
EXPDTA ELECTRON MICROSCOPY
AUTHOR W.WONG,X.C.BAI,A.BROWN,I.S.FERNANDEZ,E.HANSSEN,M.CONDRON,Y.H.TAN,
AUTHOR 2 J.BAUM,S.H.W.SCHERES
REVDAT 4 18-JUL-18 3J7A 1 REMARK
REVDAT 3 03-JUN-15 3J7A 1 JRNL
REVDAT 2 08-APR-15 3J7A 1 COMPND
REVDAT 1 16-JUL-14 3J7A 0
JRNL AUTH W.WONG,X.C.BAI,A.BROWN,I.S.FERNANDEZ,E.HANSSEN,M.CONDRON,
JRNL AUTH 2 Y.H.TAN,J.BAUM,S.H.SCHERES
JRNL TITL CRYO-EM STRUCTURE OF THE PLASMODIUM FALCIPARUM 80S RIBOSOME
JRNL TITL 2 BOUND TO THE ANTI-PROTOZOAN DRUG EMETINE.
JRNL REF ELIFE V. 3 03080 2014
JRNL REFN ESSN 2050-084X
JRNL PMID 24913268
JRNL DOI 10.7554/ELIFE.03080
REMARK 2
REMARK 2 RESOLUTION. 3.20 ANGSTROMS.
REMARK 3
REMARK 3 REFINEMENT.
REMARK 3 SOFTWARE PACKAGES : CTFFIND, RELION
REMARK 3 RECONSTRUCTION SCHEMA : NULL
REMARK 3
REMARK 3 EM MAP-MODEL FITTING AND REFINEMENT
REMARK 3 PDB ENTRY : NULL
REMARK 3 REFINEMENT SPACE : NULL
REMARK 3 REFINEMENT PROTOCOL : NULL
REMARK 3 REFINEMENT TARGET : NULL
REMARK 3 OVERALL ANISOTROPIC B VALUE : NULL
REMARK 3
REMARK 3 FITTING PROCEDURE : NULL
REMARK 3
REMARK 3 EM IMAGE RECONSTRUCTION STATISTICS
REMARK 3 NOMINAL PIXEL SIZE (ANGSTROMS) : 1.340
REMARK 3 ACTUAL PIXEL SIZE (ANGSTROMS) : NULL
REMARK 3 EFFECTIVE RESOLUTION (ANGSTROMS) : 3.200
REMARK 3 NUMBER OF PARTICLES : 105247
REMARK 3 CTF CORRECTION METHOD : NULL
REMARK 3
REMARK 3 EM RECONSTRUCTION MAGNIFICATION CALIBRATION: NULL
REMARK 3
REMARK 3 OTHER DETAILS: A NEWLY DEVELOPED STATISTICAL MOVIE PROCESSING
REMARK 3 APPROACH WAS USED TO COMPENSATE FOR BEAM-INDUCED MOVEMENT.
REMARK 4
REMARK 4 3J7A COMPLIES WITH FORMAT V. 3.30, 13-JUL-11
REMARK 100
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 16-JUN-14.
REMARK 100 THE DEPOSITION ID IS D_1000160340.
REMARK 245
REMARK 245 EXPERIMENTAL DETAILS
REMARK 245 RECONSTRUCTION METHOD : SINGLE PARTICLE
REMARK 245 SPECIMEN TYPE : VITREOUS ICE (CRYO EM)
REMARK 245
REMARK 245 ELECTRON MICROSCOPE SAMPLE
REMARK 245 SAMPLE TYPE : PARTICLE
REMARK 245 PARTICLE TYPE : POINT
REMARK 245 NAME OF SAMPLE : PLASMODIUM FALCIPARUM 80S
REMARK 245 RIBOSOME BOUND TO THE ANTI-
REMARK 245 PROTOZOAN DRUG EMETINE
REMARK 245 SAMPLE CONCENTRATION (MG ML-1) : NULL
REMARK 245 SAMPLE SUPPORT DETAILS : HOLEY CARBON GRIDS (QUANTIFOIL
REMARK 245 R2/2) WITH HOME-MADE CONTINUOUS
REMARK 245 CARBON FILM, GLOW-DISCHARGED 30
REMARK 245 SECONDS
REMARK 245 SAMPLE VITRIFICATION DETAILS : BLOT 2.5 SECONDS BEFORE
REMARK 245 PLUNGING INTO LIQUID ETHANE
REMARK 245 (FEI VITROBOT MARK IV).
REMARK 245 SAMPLE BUFFER : 20 MM HEPES, PH 7.4, 40 MM
REMARK 245 POTASSIUM ACETATE, 10 MM
REMARK 245 AMMONIUM ACETATE, 10 MM
REMARK 245 MAGNESIUM ACETATE, 5 MM BME
REMARK 245 PH : 7.40
REMARK 245 SAMPLE DETAILS : NULL
REMARK 245
REMARK 245 DATA ACQUISITION
REMARK 245 DATE OF EXPERIMENT : 19-JAN-14
REMARK 245 NUMBER OF MICROGRAPHS-IMAGES : NULL
REMARK 245 TEMPERATURE (KELVIN) : 85.00
REMARK 245 MICROSCOPE MODEL : FEI POLARA 300
REMARK 245 DETECTOR TYPE : FEI FALCON II (4K X 4K)
REMARK 245 MINIMUM DEFOCUS (NM) : 800.00
REMARK 245 MAXIMUM DEFOCUS (NM) : 3800.00
REMARK 245 MINIMUM TILT ANGLE (DEGREES) : NULL
REMARK 245 MAXIMUM TILT ANGLE (DEGREES) : NULL
REMARK 245 NOMINAL CS : 2.00
REMARK 245 IMAGING MODE : BRIGHT FIELD
REMARK 245 ELECTRON DOSE (ELECTRONS NM**-2) : 20.00
REMARK 245 ILLUMINATION MODE : FLOOD BEAM
REMARK 245 NOMINAL MAGNIFICATION : 78000
REMARK 245 CALIBRATED MAGNIFICATION : 104748
REMARK 245 SOURCE : FIELD EMISSION GUN
REMARK 245 ACCELERATION VOLTAGE (KV) : 300
REMARK 245 IMAGING DETAILS : NULL
REMARK 247
REMARK 247 ELECTRON MICROSCOPY
REMARK 247 THE COORDINATES IN THIS ENTRY WERE GENERATED FROM ELECTRON
REMARK 247 MICROSCOPY DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE
REMARK 247 THAT CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES
REMARK 247 ON THESE RECORDS ARE MEANINGLESS EXCEPT FOR THE CALCULATION
REMARK 247 OF THE STRUCTURE FACTORS.
REMARK 300
REMARK 300 BIOMOLECULE: 1
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON
REMARK 300 BURIED SURFACE AREA.
REMARK 350
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS
REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.
REMARK 350
REMARK 350 BIOMOLECULE: 1
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: 33-MERIC
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B, C, D, E, F, G, H, I, J,
REMARK 350 AND CHAINS: K, L, M, N, O, P, Q, R, S,
REMARK 350 AND CHAINS: T, U, V, W, X, Y, Z, 1, 2, 3,
REMARK 350 AND CHAINS: 4, 5, 6, 7
REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000
REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000
REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000
REMARK 465
REMARK 465 MISSING RESIDUES
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)
REMARK 465
REMARK 465 M RES C SSSEQI
REMARK 465 U A 75
REMARK 465 U A 76
REMARK 465 U A 77
REMARK 465 U A 131
REMARK 465 U A 132
REMARK 465 U A 133
REMARK 465 A A 134
REMARK 465 U A 135
REMARK 465 U A 175
REMARK 465 U A 176
REMARK 465 U A 177
REMARK 465 U A 187
REMARK 465 G A 188
REMARK 465 A A 189
REMARK 465 U A 190
REMARK 465 U A 191
REMARK 465 U A 192
REMARK 465 U A 193
REMARK 465 U A 194
REMARK 465 A A 195
REMARK 465 U A 196
REMARK 465 C A 197
REMARK 465 U A 198
REMARK 465 G A 218
REMARK 465 C A 219
REMARK 465 C A 220
REMARK 465 U A 221
REMARK 465 U A 222
REMARK 465 A A 223
REMARK 465 U A 224
REMARK 465 A A 225
REMARK 465 A A 226
REMARK 465 G A 227
REMARK 465 A A 228
REMARK 465 A A 229
REMARK 465 A A 230
REMARK 465 A A 231
REMARK 465 A A 232
REMARK 465 A A 233
REMARK 465 G A 234
REMARK 465 U A 235
REMARK 465 U A 236
REMARK 465 A A 237
REMARK 465 U A 238
REMARK 465 U A 239
REMARK 465 A A 240
REMARK 465 A A 241
REMARK 465 C A 242
REMARK 465 U A 243
REMARK 465 U A 244
REMARK 465 U A 275
REMARK 465 A A 276
REMARK 465 A A 277
REMARK 465 A A 278
REMARK 465 U A 279
REMARK 465 U A 280
REMARK 465 U A 281
REMARK 465 A A 282
REMARK 465 U A 283
REMARK 465 U A 284
REMARK 465 U A 285
REMARK 465 U A 286
REMARK 465 A A 287
REMARK 465 U A 288
REMARK 465 U A 289
REMARK 465 U A 290
REMARK 465 C A 495
REMARK 465 C A 496
REMARK 465 A A 497
REMARK 465 A A 498
REMARK 465 U A 499
REMARK 465 U A 500
REMARK 465 U A 501
REMARK 465 U A 502
REMARK 465 U A 503
REMARK 465 G A 504
REMARK 465 G A 505
REMARK 465 U A 506
REMARK 465 A A 512
REMARK 465 G A 656
REMARK 465 A A 657
REMARK 465 U A 658
REMARK 465 A A 659
REMARK 465 U A 660
REMARK 465 U A 661
REMARK 465 U A 662
REMARK 465 U A 663
REMARK 465 A A 664
REMARK 465 U A 665
REMARK 465 U A 666
REMARK 465 G A 667
REMARK 465 U A 668
REMARK 465 A A 669
REMARK 465 A A 670
REMARK 465 C A 671
REMARK 465 U A 672
REMARK 465 A A 673
REMARK 465 U A 674
REMARK 465 U A 675
REMARK 465 C A 676
REMARK 465 U A 677
REMARK 465 A A 678
REMARK 465 G A 679
REMARK 465 G A 680
REMARK 465 G A 681
REMARK 465 G A 682
REMARK 465 A A 683
REMARK 465 A A 684
REMARK 465 C A 685
REMARK 465 U A 686
REMARK 465 A A 687
REMARK 465 U A 688
REMARK 465 U A 689
REMARK 465 U A 690
REMARK 465 U A 691
REMARK 465 A A 692
REMARK 465 G A 693
REMARK 465 C A 694
REMARK 465 U A 695
REMARK 465 U A 696
REMARK 465 U A 697
REMARK 465 U A 698
REMARK 465 C A 699
REMARK 465 G A 700
REMARK 465 C A 701
REMARK 465 U A 702
REMARK 465 U A 703
REMARK 465 U A 704
REMARK 465 A A 705
REMARK 465 A A 706
REMARK 465 U A 707
REMARK 465 A A 708
REMARK 465 C A 709
REMARK 465 G A 710
REMARK 465 C A 711
REMARK 465 U A 712
REMARK 465 U A 713
REMARK 465 C A 714
REMARK 465 C A 715
REMARK 465 U A 716
REMARK 465 C A 717
REMARK 465 U A 718
REMARK 465 A A 719
REMARK 465 U A 720
REMARK 465 U A 721
REMARK 465 A A 722
REMARK 465 U A 723
REMARK 465 U A 724
REMARK 465 A A 725
REMARK 465 U A 726
REMARK 465 G A 727
REMARK 465 U A 728
REMARK 465 U A 729
REMARK 465 C A 730
REMARK 465 U A 731
REMARK 465 U A 732
REMARK 465 U A 733
REMARK 465 A A 734
REMARK 465 A A 735
REMARK 465 A A 736
REMARK 465 U A 737
REMARK 465 A A 738
REMARK 465 A A 739
REMARK 465 C A 740
REMARK 465 A A 741
REMARK 465 A A 742
REMARK 465 A A 743
REMARK 465 G A 744
REMARK 465 C A 761
REMARK 465 C A 762
REMARK 465 A A 763
REMARK 465 C A 764
REMARK 465 U A 765
REMARK 465 U A 766
REMARK 465 U A 767
REMARK 465 U A 768
REMARK 465 G A 769
REMARK 465 C A 770
REMARK 465 U A 771
REMARK 465 U A 772
REMARK 465 U A 773
REMARK 465 U A 774
REMARK 465 G A 775
REMARK 465 C A 776
REMARK 465 U A 777
REMARK 465 U A 778
REMARK 465 U A 779
REMARK 465 U A 780
REMARK 465 U A 781
REMARK 465 U A 782
REMARK 465 U A 783
REMARK 465 G A 784
REMARK 465 G A 785
REMARK 465 U A 790
REMARK 465 U A 839
REMARK 465 U A 840
REMARK 465 A A 841
REMARK 465 C A 842
REMARK 465 U A 898
REMARK 465 U A 899
REMARK 465 C A 900
REMARK 465 U A 901
REMARK 465 U A 902
REMARK 465 U A 903
REMARK 465 U A 904
REMARK 465 A A 1122
REMARK 465 G A 1125
REMARK 465 U A 1126
REMARK 465 U A 1127
REMARK 465 A A 1128
REMARK 465 A A 1129
REMARK 465 A A 1130
REMARK 465 A A 1131
REMARK 465 A A 1132
REMARK 465 U A 1133
REMARK 465 A A 1134
REMARK 465 A A 1135
REMARK 465 A A 1136
REMARK 465 A A 1137
REMARK 465 G A 1138
REMARK 465 U A 1139
REMARK 465 C A 1140
REMARK 465 A A 1141
REMARK 465 U A 1142
REMARK 465 C A 1143
REMARK 465 U A 1144
REMARK 465 U A 1145
REMARK 465 U A 1146
REMARK 465 C A 1147
REMARK 465 G A 1148
REMARK 465 A A 1149
REMARK 465 G A 1150
REMARK 465 G A 1151
REMARK 465 U A 1152
REMARK 465 G A 1153
REMARK 465 A A 1154
REMARK 465 C A 1155
REMARK 465 U A 1156
REMARK 465 U A 1157
REMARK 465 U A 1158
REMARK 465 U A 1159
REMARK 465 A A 1160
REMARK 465 G A 1161
REMARK 465 A A 1162
REMARK 465 U A 1163
REMARK 465 U A 1164
REMARK 465 A A 1323
REMARK 465 G A 1324
REMARK 465 A A 1325
REMARK 465 G A 1326
REMARK 465 U A 1327
REMARK 465 A A 1328
REMARK 465 G A 1329
REMARK 465 G A 1330
REMARK 465 A A 1331
REMARK 465 U A 1332
REMARK 465 U A 1333
REMARK 465 G A 1334
REMARK 465 A A 1335
REMARK 465 C A 1336
REMARK 465 A A 1337
REMARK 465 G A 1338
REMARK 465 A A 1339
REMARK 465 U A 1340
REMARK 465 U A 1341
REMARK 465 A A 1342
REMARK 465 A A 1343
REMARK 465 U A 1344
REMARK 465 A A 1345
REMARK 465 G A 1346
REMARK 465 C A 1347
REMARK 465 U A 1348
REMARK 465 C A 1349
REMARK 465 U A 1350
REMARK 465 U A 1351
REMARK 465 U A 1352
REMARK 465 C A 1353
REMARK 465 U A 1354
REMARK 465 U A 1355
REMARK 465 G A 1356
REMARK 465 A A 1357
REMARK 465 U A 1358
REMARK 465 U A 1359
REMARK 465 U A 1360
REMARK 465 C A 1361
REMARK 465 U A 1398
REMARK 465 A A 1399
REMARK 465 A A 1465
REMARK 465 U A 1466
REMARK 465 A A 1467
REMARK 465 U A 1468
REMARK 465 U A 1469
REMARK 465 C A 1470
REMARK 465 U A 1471
REMARK 465 U A 1472
REMARK 465 A A 1473
REMARK 465 U A 1474
REMARK 465 U A 1475
REMARK 465 U A 1476
REMARK 465 G A 1477
REMARK 465 A A 1478
REMARK 465 A A 1479
REMARK 465 A A 1480
REMARK 465 U A 1481
REMARK 465 U A 1482
REMARK 465 G A 1483
REMARK 465 A A 1484
REMARK 465 A A 1485
REMARK 465 C A 1486
REMARK 465 A A 1487
REMARK 465 U A 1488
REMARK 465 A A 1489
REMARK 465 G A 1490
REMARK 465 G A 1491
REMARK 465 U A 1492
REMARK 465 A A 1493
REMARK 465 A A 1494
REMARK 465 C A 1495
REMARK 465 U A 1496
REMARK 465 A A 1497
REMARK 465 U A 1498
REMARK 465 A A 1499
REMARK 465 C A 1500
REMARK 465 A A 1501
REMARK 465 U A 1502
REMARK 465 U A 1503
REMARK 465 U A 1504
REMARK 465 A A 1505
REMARK 465 U A 1506
REMARK 465 U A 1507
REMARK 465 C A 1508
REMARK 465 A A 1509
REMARK 465 G A 1510
REMARK 465 U A 1511
REMARK 465 A A 1512
REMARK 465 A A 1513
REMARK 465 U A 1514
REMARK 465 C A 1515
REMARK 465 A A 1516
REMARK 465 A A 1517
REMARK 465 A A 1518
REMARK 465 U A 1519
REMARK 465 U A 1520
REMARK 465 A A 1521
REMARK 465 G A 1522
REMARK 465 G A 1523
REMARK 465 A A 1524
REMARK 465 U A 1525
REMARK 465 A A 1526
REMARK 465 U A 1527
REMARK 465 U A 1528
REMARK 465 U A 1529
REMARK 465 U A 1530
REMARK 465 U A 1531
REMARK 465 A A 1532
REMARK 465 U A 1533
REMARK 465 U A 1534
REMARK 465 A A 1535
REMARK 465 A A 1536
REMARK 465 A A 1537
REMARK 465 A A 1538
REMARK 465 U A 1539
REMARK 465 A A 1540
REMARK 465 U A 1541
REMARK 465 C A 1542
REMARK 465 C A 1543
REMARK 465 U A 1544
REMARK 465 U A 1545
REMARK 465 U A 1546
REMARK 465 U A 1547
REMARK 465 C A 1548
REMARK 465 C A 1549
REMARK 465 C A 1550
REMARK 465 U A 1551
REMARK 465 G A 1552
REMARK 465 U A 1553
REMARK 465 U A 1554
REMARK 465 C A 1555
REMARK 465 U A 1556
REMARK 465 A A 1557
REMARK 465 C A 1558
REMARK 465 U A 1559
REMARK 465 A A 1560
REMARK 465 A A 1561
REMARK 465 U A 1562
REMARK 465 A A 1563
REMARK 465 A A 1564
REMARK 465 U A 1565
REMARK 465 U A 1566
REMARK 465 U A 1567
REMARK 465 G A 1568
REMARK 465 U A 1569
REMARK 465 U A 1570
REMARK 465 U A 1571
REMARK 465 U A 1572
REMARK 465 U A 1573
REMARK 465 U A 1574
REMARK 465 A A 1575
REMARK 465 C A 1576
REMARK 465 U A 1577
REMARK 465 C A 1578
REMARK 465 U A 1579
REMARK 465 A A 1580
REMARK 465 U A 1581
REMARK 465 U A 1582
REMARK 465 U A 1583
REMARK 465 C A 1584
REMARK 465 U A 1585
REMARK 465 C A 1586
REMARK 465 U A 1587
REMARK 465 C A 1588
REMARK 465 U A 1589
REMARK 465 U A 1590
REMARK 465 C A 1591
REMARK 465 U A 1592
REMARK 465 U A 1593
REMARK 465 U A 1594
REMARK 465 U A 1595
REMARK 465 A A 1596
REMARK 465 A A 1597
REMARK 465 G A 1598
REMARK 465 A A 1599
REMARK 465 A A 1600
REMARK 465 U A 1601
REMARK 465 U A 1611
REMARK 465 G A 1612
REMARK 465 A A 1613
REMARK 465 U A 1614
REMARK 465 U A 1615
REMARK 465 G A 1616
REMARK 465 A A 1617
REMARK 465 A A 1618
REMARK 465 A A 1619
REMARK 465 A A 1620
REMARK 465 U A 1736
REMARK 465 U A 1737
REMARK 465 U A 1738
REMARK 465 U A 1739
REMARK 465 A A 1740
REMARK 465 U A 1751
REMARK 465 A A 1752
REMARK 465 U A 1753
REMARK 465 A A 1754
REMARK 465 U A 1755
REMARK 465 U A 1756
REMARK 465 U A 1757
REMARK 465 G A 1758
REMARK 465 U A 1759
REMARK 465 A A 1760
REMARK 465 U A 1761
REMARK 465 C A 1762
REMARK 465 U A 1763
REMARK 465 U A 1764
REMARK 465 U A 1765
REMARK 465 G A 1766
REMARK 465 A A 1767
REMARK 465 U A 1768
REMARK 465 G A 1769
REMARK 465 C A 1770
REMARK 465 U A 1771
REMARK 465 U A 1772
REMARK 465 A A 1773
REMARK 465 U A 1774
REMARK 465 A A 1775
REMARK 465 U A 1776
REMARK 465 U A 1777
REMARK 465 U A 1778
REMARK 465 U A 1988
REMARK 465 U A 1989
REMARK 465 G A 1990
REMARK 465 A A 1991
REMARK 465 A A 1992
REMARK 465 U A 1993
REMARK 465 U A 1994
REMARK 465 A A 1995
REMARK 465 U A 1996
REMARK 465 A A 1997
REMARK 465 U A 1998
REMARK 465 U A 1999
REMARK 465 C A 2000
REMARK 465 U A 2001
REMARK 465 U A 2002
REMARK 465 U A 2091
REMARK 465 A A 2092
REMARK 465 MET B 1
REMARK 465 ALA B 2
REMARK 465 VAL B 3
REMARK 465 GLY B 4
REMARK 465 LYS B 5
REMARK 465 ASN B 6
REMARK 465 LYS B 7
REMARK 465 ARG B 8
REMARK 465 THR B 9
REMARK 465 SER B 10
REMARK 465 LYS B 11
REMARK 465 GLY B 12
REMARK 465 LYS B 13
REMARK 465 LYS B 14
REMARK 465 GLY B 15
REMARK 465 GLY B 16
REMARK 465 LYS B 17
REMARK 465 LYS B 18
REMARK 465 LYS B 19
REMARK 465 VAL B 20
REMARK 465 THR B 21
REMARK 465 ASP B 22
REMARK 465 VAL B 23
REMARK 465 ASP B 234
REMARK 465 PRO B 235
REMARK 465 LYS B 236
REMARK 465 GLU B 237
REMARK 465 GLU B 238
REMARK 465 SER B 239
REMARK 465 GLY B 240
REMARK 465 LYS B 241
REMARK 465 ASN B 242
REMARK 465 VAL B 243
REMARK 465 ASN B 244
REMARK 465 ALA B 245
REMARK 465 LEU B 246
REMARK 465 PRO B 247
REMARK 465 GLU B 248
REMARK 465 SER B 249
REMARK 465 LYS B 250
REMARK 465 GLU B 251
REMARK 465 ALA B 252
REMARK 465 THR B 253
REMARK 465 ASN B 254
REMARK 465 ILE B 255
REMARK 465 LEU B 256
REMARK 465 THR B 257
REMARK 465 ALA B 258
REMARK 465 GLU B 259
REMARK 465 LEU B 260
REMARK 465 LYS B 261
REMARK 465 HIS B 262
REMARK 465 MET C 1
REMARK 465 SER C 2
REMARK 465 ASN C 3
REMARK 465 LYS C 4
REMARK 465 LYS C 5
REMARK 465 GLY C 6
REMARK 465 GLN C 7
REMARK 465 SER C 8
REMARK 465 PRO C 9
REMARK 465 ASP C 205
REMARK 465 PRO C 206
REMARK 465 GLU C 207
REMARK 465 GLN C 208
REMARK 465 PHE C 209
REMARK 465 GLU C 210
REMARK 465 LEU C 211
REMARK 465 LYS C 212
REMARK 465 ASN C 213
REMARK 465 LEU C 214
REMARK 465 ALA C 215
REMARK 465 ASN C 216
REMARK 465 GLU C 217
REMARK 465 GLU C 218
REMARK 465 ASN C 219
REMARK 465 THR C 220
REMARK 465 PRO C 221
REMARK 465 THR C 222
REMARK 465 ALA C 223
REMARK 465 PRO C 224
REMARK 465 HIS C 225
REMARK 465 LEU C 226
REMARK 465 ILE C 227
REMARK 465 GLU C 228
REMARK 465 ASN C 229
REMARK 465 GLN C 230
REMARK 465 TYR C 231
REMARK 465 ALA C 232
REMARK 465 ALA C 233
REMARK 465 GLU C 234
REMARK 465 ALA C 235
REMARK 465 PRO C 236
REMARK 465 TYR C 237
REMARK 465 ASP C 238
REMARK 465 GLU C 239
REMARK 465 TRP C 240
REMARK 465 THR C 241
REMARK 465 LYS C 242
REMARK 465 LYS C 243
REMARK 465 GLU C 244
REMARK 465 GLU C 245
REMARK 465 TRP C 246
REMARK 465 ASN C 247
REMARK 465 ASP C 248
REMARK 465 ASN C 249
REMARK 465 THR C 250
REMARK 465 ASN C 251
REMARK 465 GLU C 252
REMARK 465 ASP C 253
REMARK 465 TRP C 254
REMARK 465 LYS C 255
REMARK 465 ASN C 256
REMARK 465 PRO C 257
REMARK 465 ILE C 258
REMARK 465 ALA C 259
REMARK 465 ALA C 260
REMARK 465 GLU C 261
REMARK 465 GLU C 262
REMARK 465 TRP C 263
REMARK 465 MET D 1
REMARK 465 SER D 2
REMARK 465 ALA D 3
REMARK 465 ARG D 40
REMARK 465 VAL D 41
REMARK 465 THR D 42
REMARK 465 PRO D 43
REMARK 465 ILE D 44
REMARK 465 ARG D 45
REMARK 465 THR D 46
REMARK 465 GLU D 47
REMARK 465 VAL D 48
REMARK 465 ILE D 49
REMARK 465 ILE D 50
REMARK 465 ARG D 51
REMARK 465 ALA D 52
REMARK 465 THR D 53
REMARK 465 ARG D 54
REMARK 465 THR D 55
REMARK 465 ARG D 56
REMARK 465 GLU D 57
REMARK 465 VAL D 58
REMARK 465 LEU D 59
REMARK 465 GLY D 60
REMARK 465 ASP D 61
REMARK 465 LYS D 62
REMARK 465 GLY D 63
REMARK 465 ARG D 64
REMARK 465 ASN D 79
REMARK 465 LYS D 80
REMARK 465 SER D 81
REMARK 465 THR D 82
REMARK 465 ASN D 83
REMARK 465 SER D 84
REMARK 465 VAL D 85
REMARK 465 GLU D 86
REMARK 465 LEU D 87
REMARK 465 PHE D 88
REMARK 465 ALA D 89
REMARK 465 GLU D 90
REMARK 465 ARG D 91
REMARK 465 VAL D 92
REMARK 465 GLU D 93
REMARK 465 HIS D 94
REMARK 465 ARG D 95
REMARK 465 GLY D 96
REMARK 465 ALA D 198
REMARK 465 ILE D 199
REMARK 465 ASP D 200
REMARK 465 THR D 201
REMARK 465 ARG D 202
REMARK 465 THR D 203
REMARK 465 GLY D 204
REMARK 465 LEU D 205
REMARK 465 THR D 206
REMARK 465 GLU D 217
REMARK 465 PRO D 218
REMARK 465 LYS D 219
REMARK 465 THR D 220
REMARK 465 ASP D 221
REMARK 465 THR D 222
REMARK 465 VAL D 223
REMARK 465 ASP D 224
REMARK 465 LEU D 225
REMARK 465 MET E 1
REMARK 465 GLU E 187
REMARK 465 ALA E 188
REMARK 465 GLU E 189
REMARK 465 MET F 1
REMARK 465 LEU F 259
REMARK 465 ASN F 260
REMARK 465 ASN F 261
REMARK 465 MET G 1
REMARK 465 GLU G 2
REMARK 465 ASP G 3
REMARK 465 ARG G 4
REMARK 465 GLY G 5
REMARK 465 GLY G 6
REMARK 465 PHE G 7
REMARK 465 SER G 8
REMARK 465 ARG G 9
REMARK 465 GLY G 10
REMARK 465 PHE G 11
REMARK 465 GLY G 12
REMARK 465 ARG G 13
REMARK 465 GLY G 14
REMARK 465 VAL G 15
REMARK 465 ARG G 16
REMARK 465 GLY G 17
REMARK 465 THR G 18
REMARK 465 ARG G 19
REMARK 465 GLY G 20
REMARK 465 ARG G 21
REMARK 465 GLY G 22
REMARK 465 GLY G 23
REMARK 465 ARG G 24
REMARK 465 GLY G 25
REMARK 465 ALA G 26
REMARK 465 ARG G 27
REMARK 465 GLY G 28
REMARK 465 ARG G 29
REMARK 465 GLY G 30
REMARK 465 ARG G 31
REMARK 465 GLY G 32
REMARK 465 SER G 33
REMARK 465 ALA G 34
REMARK 465 GLU G 35
REMARK 465 ASP G 36
REMARK 465 ASP G 37
REMARK 465 LEU G 38
REMARK 465 GLN G 263
REMARK 465 ASN G 264
REMARK 465 LEU G 265
REMARK 465 LYS G 266
REMARK 465 GLY G 267
REMARK 465 ILE G 268
REMARK 465 LYS G 269
REMARK 465 GLY G 270
REMARK 465 THR G 271
REMARK 465 VAL G 272
REMARK 465 ALA H 161
REMARK 465 ILE H 162
REMARK 465 THR H 163
REMARK 465 LYS H 164
REMARK 465 ASN H 165
REMARK 465 GLY H 166
REMARK 465 LYS H 167
REMARK 465 THR H 168
REMARK 465 LYS H 169
REMARK 465 LYS H 214
REMARK 465 TYR H 215
REMARK 465 ARG H 216
REMARK 465 SER H 217
REMARK 465 GLU H 218
REMARK 465 LEU H 219
REMARK 465 ASN H 220
REMARK 465 GLN H 221
REMARK 465 GLN H 222
REMARK 465 HIS H 223
REMARK 465 ASP H 224
REMARK 465 VAL H 225
REMARK 465 GLU H 226
REMARK 465 THR H 227
REMARK 465 THR H 228
REMARK 465 LYS H 229
REMARK 465 LYS H 230
REMARK 465 LYS H 231
REMARK 465 LYS H 232
REMARK 465 VAL H 233
REMARK 465 LYS H 234
REMARK 465 LYS H 235
REMARK 465 SER H 236
REMARK 465 LEU H 237
REMARK 465 SER H 238
REMARK 465 LYS H 239
REMARK 465 THR H 240
REMARK 465 ASN H 241
REMARK 465 LYS H 242
REMARK 465 THR H 243
REMARK 465 ALA H 244
REMARK 465 SER H 245
REMARK 465 LYS H 246
REMARK 465 SER H 247
REMARK 465 LYS H 248
REMARK 465 LEU H 249
REMARK 465 ASN H 250
REMARK 465 THR H 251
REMARK 465 LYS H 252
REMARK 465 GLN H 253
REMARK 465 GLU H 254
REMARK 465 GLN H 255
REMARK 465 LYS H 256
REMARK 465 ASP H 257
REMARK 465 LYS H 258
REMARK 465 THR H 259
REMARK 465 GLU H 260
REMARK 465 LYS H 261
REMARK 465 LYS H 262
REMARK 465 GLN H 263
REMARK 465 ASN H 264
REMARK 465 LYS H 265
REMARK 465 THR H 266
REMARK 465 ASN H 267
REMARK 465 ASN H 268
REMARK 465 ILE H 269
REMARK 465 LYS H 270
REMARK 465 ASN H 271
REMARK 465 ASP H 272
REMARK 465 LYS H 273
REMARK 465 SER H 274
REMARK 465 GLU H 275
REMARK 465 LYS H 276
REMARK 465 LYS H 277
REMARK 465 GLU H 278
REMARK 465 GLN H 279
REMARK 465 ALA H 280
REMARK 465 LYS H 281
REMARK 465 LYS H 282
REMARK 465 LYS H 283
REMARK 465 THR H 284
REMARK 465 LYS H 285
REMARK 465 THR H 286
REMARK 465 ASN H 287
REMARK 465 GLU H 288
REMARK 465 ASN H 289
REMARK 465 THR H 290
REMARK 465 GLN H 291
REMARK 465 GLN H 292
REMARK 465 THR H 293
REMARK 465 LYS H 294
REMARK 465 GLN H 295
REMARK 465 ASN H 296
REMARK 465 LYS H 297
REMARK 465 PRO H 298
REMARK 465 ASP H 299
REMARK 465 LYS H 300
REMARK 465 LYS H 301
REMARK 465 ASN H 302
REMARK 465 LYS H 303
REMARK 465 ALA H 304
REMARK 465 LYS H 305
REMARK 465 LYS H 306
REMARK 465 MET I 1
REMARK 465 GLU I 2
REMARK 465 THR I 3
REMARK 465 THR I 4
REMARK 465 THR I 5
REMARK 465 ALA I 6
REMARK 465 ILE I 119
REMARK 465 GLY I 120
REMARK 465 SER I 121
REMARK 465 ALA I 122
REMARK 465 GLY I 123
REMARK 465 VAL I 124
REMARK 465 VAL I 125
REMARK 465 ARG I 126
REMARK 465 ARG I 127
REMARK 465 MET J 1
REMARK 465 ASP J 2
REMARK 465 THR J 191
REMARK 465 ASN J 192
REMARK 465 GLU J 193
REMARK 465 LYS J 194
REMARK 465 MET K 1
REMARK 465 MET L 1
REMARK 465 GLY L 2
REMARK 465 ILE L 3
REMARK 465 SER L 4
REMARK 465 LEU L 121
REMARK 465 GLY L 122
REMARK 465 LYS L 123
REMARK 465 LYS L 124
REMARK 465 LYS L 125
REMARK 465 LYS L 126
REMARK 465 GLU L 127
REMARK 465 LYS L 128
REMARK 465 LYS L 129
REMARK 465 GLU L 130
REMARK 465 GLU L 131
REMARK 465 ASP L 132
REMARK 465 ASN L 133
REMARK 465 LYS L 134
REMARK 465 GLU L 135
REMARK 465 GLU L 136
REMARK 465 ASN L 137
REMARK 465 LYS L 138
REMARK 465 GLN L 139
REMARK 465 GLU L 140
REMARK 465 VAL L 141
REMARK 465 GLU L 142
REMARK 465 ASN L 143
REMARK 465 ASN L 144
REMARK 465 GLU L 145
REMARK 465 GLU L 146
REMARK 465 ALA L 147
REMARK 465 ALA L 148
REMARK 465 LYS L 149
REMARK 465 ASP L 150
REMARK 465 GLU L 151
REMARK 465 THR L 152
REMARK 465 THR L 153
REMARK 465 LYS L 154
REMARK 465 THR L 155
REMARK 465 TYR L 156
REMARK 465 GLY L 157
REMARK 465 VAL L 158
REMARK 465 ILE L 159
REMARK 465 LYS L 160
REMARK 465 LYS L 214
REMARK 465 LYS L 215
REMARK 465 MET M 1
REMARK 465 THR M 2
REMARK 465 THR M 3
REMARK 465 LYS M 4
REMARK 465 VAL M 5
REMARK 465 ARG M 144
REMARK 465 MET N 1
REMARK 465 SER N 2
REMARK 465 LYS N 3
REMARK 465 LEU N 4
REMARK 465 MET N 5
REMARK 465 LYS N 6
REMARK 465 GLY N 7
REMARK 465 ALA N 8
REMARK 465 ILE N 9
REMARK 465 ASP N 10
REMARK 465 ASN N 11
REMARK 465 GLU N 12
REMARK 465 LYS N 13
REMARK 465 TYR N 14
REMARK 465 ARG N 15
REMARK 465 LEU N 16
REMARK 465 ARG N 17
REMARK 465 ARG N 18
REMARK 465 ILE N 19
REMARK 465 ARG N 20
REMARK 465 MET O 1
REMARK 465 ASP O 2
REMARK 465 LYS O 3
REMARK 465 GLN O 4
REMARK 465 THR O 5
REMARK 465 LEU O 6
REMARK 465 PRO O 7
REMARK 465 HIS O 8
REMARK 465 HIS O 9
REMARK 465 LYS O 10
REMARK 465 PHE O 90
REMARK 465 LEU O 91
REMARK 465 HIS O 92
REMARK 465 LEU O 93
REMARK 465 PRO O 94
REMARK 465 PRO O 95
REMARK 465 SER O 96
REMARK 465 ILE O 97
REMARK 465 PHE O 98
REMARK 465 PRO O 99
REMARK 465 ALA O 100
REMARK 465 THR O 101
REMARK 465 LEU O 102
REMARK 465 SER O 103
REMARK 465 LYS O 104
REMARK 465 LYS O 105
REMARK 465 THR O 106
REMARK 465 VAL O 107
REMARK 465 ASN O 108
REMARK 465 ARG O 109
REMARK 465 ALA O 110
REMARK 465 PRO O 111
REMARK 465 LYS O 112
REMARK 465 MET O 113
REMARK 465 ASP O 114
REMARK 465 GLU O 115
REMARK 465 ASP O 116
REMARK 465 ILE O 117
REMARK 465 SER O 118
REMARK 465 ARG O 119
REMARK 465 ASP O 120
REMARK 465 VAL O 121
REMARK 465 ARG O 122
REMARK 465 GLN O 123
REMARK 465 PRO O 124
REMARK 465 MET O 125
REMARK 465 GLY O 126
REMARK 465 ARG O 127
REMARK 465 GLY O 128
REMARK 465 ARG O 129
REMARK 465 ALA O 130
REMARK 465 PHE O 131
REMARK 465 ASP O 132
REMARK 465 ARG O 133
REMARK 465 ARG O 134
REMARK 465 PRO O 135
REMARK 465 PHE O 136
REMARK 465 GLU O 137
REMARK 465 MET P 1
REMARK 465 ALA P 2
REMARK 465 SER P 3
REMARK 465 LYS P 4
REMARK 465 LYS P 5
REMARK 465 VAL P 6
REMARK 465 LYS P 7
REMARK 465 THR P 8
REMARK 465 PRO P 9
REMARK 465 GLN P 10
REMARK 465 PRO P 11
REMARK 465 GLU P 12
REMARK 465 THR P 13
REMARK 465 ALA P 14
REMARK 465 ILE P 15
REMARK 465 VAL P 16
REMARK 465 SER P 17
REMARK 465 GLY P 18
REMARK 465 PRO P 19
REMARK 465 GLN P 20
REMARK 465 PRO P 21
REMARK 465 LYS P 22
REMARK 465 GLU P 23
REMARK 465 GLY P 24
REMARK 465 MET Q 1
REMARK 465 MET R 1
REMARK 465 SER R 2
REMARK 465 ASP R 3
REMARK 465 VAL R 4
REMARK 465 GLU R 5
REMARK 465 SER R 6
REMARK 465 ALA R 7
REMARK 465 ASP R 8
REMARK 465 ASN R 9
REMARK 465 ASN R 10
REMARK 465 VAL R 11
REMARK 465 VAL R 12
REMARK 465 VAL R 13
REMARK 465 GLU R 14
REMARK 465 GLU R 15
REMARK 465 LYS R 16
REMARK 465 ALA R 17
REMARK 465 VAL R 18
REMARK 465 PHE R 19
REMARK 465 ASP R 20
REMARK 465 ASN R 21
REMARK 465 LYS R 79
REMARK 465 ASN R 80
REMARK 465 ILE R 81
REMARK 465 PRO R 82
REMARK 465 LEU R 83
REMARK 465 PHE R 84
REMARK 465 LYS R 101
REMARK 465 LEU R 102
REMARK 465 ASP R 103
REMARK 465 ASN R 104
REMARK 465 GLU R 105
REMARK 465 GLY R 106
REMARK 465 ASN R 107
REMARK 465 ALA R 108
REMARK 465 ARG R 109
REMARK 465 LYS R 110
REMARK 465 ASN R 136
REMARK 465 GLN R 137
REMARK 465 THR R 138
REMARK 465 VAL R 139
REMARK 465 THR R 140
REMARK 465 ALA R 141
REMARK 465 MET S 1
REMARK 465 SER S 2
REMARK 465 LEU S 3
REMARK 465 GLN S 4
REMARK 465 VAL S 5
REMARK 465 ILE S 6
REMARK 465 ASP S 7
REMARK 465 ASN S 8
REMARK 465 ASN S 9
REMARK 465 ASP S 10
REMARK 465 PHE S 11
REMARK 465 THR S 140
REMARK 465 THR S 141
REMARK 465 GLY S 142
REMARK 465 ARG S 143
REMARK 465 ARG S 144
REMARK 465 GLY S 145
REMARK 465 ARG S 146
REMARK 465 THR S 147
REMARK 465 VAL S 148
REMARK 465 GLY S 149
REMARK 465 VAL S 150
REMARK 465 ALA S 151
REMARK 465 LYS S 152
REMARK 465 LYS S 153
REMARK 465 LYS S 154
REMARK 465 GLY S 155
REMARK 465 ALA S 156
REMARK 465 MET T 1
REMARK 465 GLY T 2
REMARK 465 CYS T 3
REMARK 465 ILE T 4
REMARK 465 LEU T 5
REMARK 465 ASN T 6
REMARK 465 MET U 1
REMARK 465 GLY U 2
REMARK 465 MET V 1
REMARK 465 ALA V 2
REMARK 465 THR V 3
REMARK 465 THR V 4
REMARK 465 LEU V 5
REMARK 465 LYS V 26
REMARK 465 ILE V 27
REMARK 465 LYS V 28
REMARK 465 LYS V 29
REMARK 465 GLY V 30
REMARK 465 SER V 31
REMARK 465 LYS V 32
REMARK 465 SER V 33
REMARK 465 TYR V 34
REMARK 465 ILE V 35
REMARK 465 MET W 1
REMARK 465 GLY W 2
REMARK 465 PHE W 84
REMARK 465 VAL W 85
REMARK 465 PRO W 86
REMARK 465 GLU W 87
REMARK 465 LYS W 88
REMARK 465 SER W 89
REMARK 465 GLN W 90
REMARK 465 ILE W 91
REMARK 465 ASP W 92
REMARK 465 VAL W 93
REMARK 465 SER W 94
REMARK 465 VAL W 95
REMARK 465 ILE W 96
REMARK 465 ILE W 111
REMARK 465 ASN W 112
REMARK 465 ILE W 113
REMARK 465 SER W 114
REMARK 465 ASN W 115
REMARK 465 MET W 116
REMARK 465 LYS W 117
REMARK 465 VAL W 118
REMARK 465 HIS W 119
REMARK 465 ASN W 120
REMARK 465 PRO W 121
REMARK 465 MET W 122
REMARK 465 ILE W 123
REMARK 465 ASN W 124
REMARK 465 THR W 125
REMARK 465 ASN W 126
REMARK 465 GLN W 127
REMARK 465 GLN W 128
REMARK 465 LYS W 129
REMARK 465 GLN W 130
REMARK 465 ASN W 131
REMARK 465 ARG W 132
REMARK 465 MET W 133
REMARK 465 ASN W 134
REMARK 465 ASN W 135
REMARK 465 GLN W 136
REMARK 465 PHE W 137
REMARK 465 MET X 1
REMARK 465 GLU X 2
REMARK 465 ASP X 3
REMARK 465 ALA X 4
REMARK 465 ASN X 5
REMARK 465 LYS X 6
REMARK 465 PRO X 7
REMARK 465 LYS X 8
REMARK 465 LYS X 9
REMARK 465 ARG X 10
REMARK 465 THR X 11
REMARK 465 PHE X 12
REMARK 465 ARG X 13
REMARK 465 THR X 14
REMARK 465 PHE X 15
REMARK 465 GLN X 16
REMARK 465 TYR X 17
REMARK 465 ARG X 18
REMARK 465 GLY X 19
REMARK 465 VAL X 20
REMARK 465 VAL X 96
REMARK 465 HIS X 97
REMARK 465 ASN X 98
REMARK 465 GLY X 99
REMARK 465 LYS X 100
REMARK 465 GLN X 101
REMARK 465 TYR X 102
REMARK 465 LYS X 124
REMARK 465 HIS X 125
REMARK 465 THR X 126
REMARK 465 ARG X 127
REMARK 465 HIS X 128
REMARK 465 GLY X 129
REMARK 465 LYS X 130
REMARK 465 PRO X 131
REMARK 465 GLY X 132
REMARK 465 ILE X 133
REMARK 465 GLY X 134
REMARK 465 ALA X 135
REMARK 465 THR X 136
REMARK 465 HIS X 137
REMARK 465 SER X 138
REMARK 465 SER X 139
REMARK 465 ARG X 140
REMARK 465 PHE X 141
REMARK 465 ILE X 142
REMARK 465 PRO X 143
REMARK 465 LEU X 144
REMARK 465 LYS X 145
REMARK 465 MET Y 1
REMARK 465 ALA Y 2
REMARK 465 GLU Y 3
REMARK 465 GLN Y 4
REMARK 465 PHE Y 5
REMARK 465 THR Y 6
REMARK 465 GLU Y 7
REMARK 465 ASP Y 8
REMARK 465 ILE Y 9
REMARK 465 GLY Y 10
REMARK 465 VAL Y 11
REMARK 465 VAL Y 12
REMARK 465 ASN Y 13
REMARK 465 LYS Y 14
REMARK 465 LYS Y 169
REMARK 465 GLU Y 170
REMARK 465 MET Z 1
REMARK 465 PHE Z 2
REMARK 465 ASN Z 3
REMARK 465 ASP Z 4
REMARK 465 GLN Z 5
REMARK 465 LYS Z 6
REMARK 465 VAL Z 7
REMARK 465 LEU Z 8
REMARK 465 VAL Z 9
REMARK 465 ASP Z 10
REMARK 465 MET 1 1
REMARK 465 THR 1 2
REMARK 465 GLU 1 123
REMARK 465 LYS 1 124
REMARK 465 THR 1 125
REMARK 465 LYS 1 126
REMARK 465 VAL 1 127
REMARK 465 SER 1 128
REMARK 465 GLY 1 129
REMARK 465 ALA 1 130
REMARK 465 LYS 1 131
REMARK 465 LYS 1 132
REMARK 465 LYS 1 133
REMARK 465 MET 2 1
REMARK 465 PRO 2 2
REMARK 465 PRO 2 3
REMARK 465 LYS 2 4
REMARK 465 GLU 2 5
REMARK 465 ARG 2 6
REMARK 465 LYS 2 7
REMARK 465 THR 2 8
REMARK 465 LYS 2 9
REMARK 465 GLU 2 10
REMARK 465 GLN 2 11
REMARK 465 ILE 2 12
REMARK 465 ALA 2 13
REMARK 465 ALA 2 14
REMARK 465 ALA 2 15
REMARK 465 ALA 2 16
REMARK 465 ALA 2 17
REMARK 465 ALA 2 18
REMARK 465 SER 2 19
REMARK 465 GLY 2 20
REMARK 465 ARG 2 21
REMARK 465 THR 2 22
REMARK 465 LYS 2 23
REMARK 465 LYS 2 24
REMARK 465 LYS 2 25
REMARK 465 LYS 2 26
REMARK 465 TRP 2 27
REMARK 465 GLY 2 28
REMARK 465 LYS 2 29
REMARK 465 GLY 2 30
REMARK 465 LYS 2 31
REMARK 465 ASN 2 32
REMARK 465 LYS 2 33
REMARK 465 GLU 2 34
REMARK 465 ASP 2 43
REMARK 465 LYS 2 44
REMARK 465 SER 2 45
REMARK 465 LEU 2 46
REMARK 465 HIS 2 47
REMARK 465 SER 2 48
REMARK 465 LYS 2 49
REMARK 465 ILE 2 50
REMARK 465 LEU 2 51
REMARK 465 GLU 2 52
REMARK 465 CYS 2 53
REMARK 465 LYS 2 54
REMARK 465 ASN 2 55
REMARK 465 MET 2 56
REMARK 465 LYS 2 57
REMARK 465 LYS 2 85
REMARK 465 LYS 2 86
REMARK 465 LEU 2 87
REMARK 465 ILE 2 88
REMARK 465 ALA 2 89
REMARK 465 GLU 2 90
REMARK 465 VAL 2 91
REMARK 465 CYS 2 92
REMARK 465 VAL 2 93
REMARK 465 GLN 2 94
REMARK 465 SER 2 95
REMARK 465 HIS 2 96
REMARK 465 LYS 2 103
REMARK 465 VAL 2 104
REMARK 465 ALA 2 105
REMARK 465 MET 3 1
REMARK 465 GLU 3 97
REMARK 465 THR 3 98
REMARK 465 ALA 3 99
REMARK 465 LYS 3 100
REMARK 465 HIS 3 101
REMARK 465 VAL 3 102
REMARK 465 ASN 3 103
REMARK 465 PRO 3 104
REMARK 465 SER 3 105
REMARK 465 GLN 3 106
REMARK 465 LEU 3 107
REMARK 465 MET 4 1
REMARK 465 ASN 4 2
REMARK 465 VAL 4 3
REMARK 465 ASP 4 4
REMARK 465 LEU 4 5
REMARK 465 LEU 4 6
REMARK 465 MET 5 1
REMARK 465 MET 5 30
REMARK 465 GLY 5 31
REMARK 465 ASP 5 32
REMARK 465 SER 5 33
REMARK 465 GLU 5 34
REMARK 465 LEU 5 35
REMARK 465 ALA 5 36
REMARK 465 ARG 5 67
REMARK 465 MET 6 1
REMARK 465 GLY 6 2
REMARK 465 LYS 6 3
REMARK 465 VAL 6 4
REMARK 465 HIS 6 5
REMARK 465 GLY 6 49
REMARK 465 ARG 6 50
REMARK 465 LYS 6 51
REMARK 465 LYS 6 52
REMARK 465 GLY 6 53
REMARK 465 PRO 6 54
REMARK 465 ASN 6 55
REMARK 465 SER 6 56
REMARK 465 LYS 6 57
REMARK 465 ALA 6 58
REMARK 470
REMARK 470 MISSING ATOM
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;
REMARK 470 I=INSERTION CODE):
REMARK 470 M RES CSSEQI ATOMS
REMARK 470 ARG E 171 CG CD NE CZ NH1 NH2
REMARK 470 LYS E 173 CG CD CE NZ
REMARK 470 ARG E 174 CG CD NE CZ NH1 NH2
REMARK 470 LYS E 175 CG CD CE NZ
REMARK 470 ARG H 160 CB CG CD NE CZ NH1 NH2
REMARK 470 GLN S 136 CG CD OE1 NE2
REMARK 470 LYS 1 118 CG CD CE NZ
REMARK 470 ARG 5 61 CG CD NE CZ NH1 NH2
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT
REMARK 500
REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT.
REMARK 500
REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI DISTANCE
REMARK 500 O ILE S 35 CG1 ILE S 38 1.76
REMARK 500 O2 C A 759 C2 A A 788 1.84
REMARK 500 O THR S 33 CG1 ILE S 38 2.05
REMARK 500 O2' A A 1061 O2 U A 2077 2.17
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: COVALENT BOND LENGTHS
REMARK 500
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT: (10X,I3,1X,2(A3,1X,A1,I4,A1,1X,A4,3X),1X,F6.3)
REMARK 500
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996
REMARK 500
REMARK 500 M RES CSSEQI ATM1 RES CSSEQI ATM2 DEVIATION
REMARK 500 A A 788 O3' U A 789 P 0.096
REMARK 500 U A 789 C1' U A 789 N1 0.104
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES
REMARK 500
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)
REMARK 500
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996
REMARK 500
REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3
REMARK 500 A A 246 C2' - C3' - O3' ANGL. DEV. = 9.9 DEGREES
REMARK 500 A A 291 C2' - C3' - O3' ANGL. DEV. = 10.3 DEGREES
REMARK 500 G A 465 C2' - C3' - O3' ANGL. DEV. = 10.1 DEGREES
REMARK 500 G A 525 C2' - C3' - O3' ANGL. DEV. = 10.8 DEGREES
REMARK 500 A A 788 C3' - O3' - P ANGL. DEV. = -13.0 DEGREES
REMARK 500 U A 789 O3' - P - OP2 ANGL. DEV. = 11.8 DEGREES
REMARK 500 G A 850 C2' - C3' - O3' ANGL. DEV. = 12.8 DEGREES
REMARK 500 C A1381 C2' - C3' - O3' ANGL. DEV. = 11.7 DEGREES
REMARK 500 U A1386 C2' - C3' - O3' ANGL. DEV. = 11.6 DEGREES
REMARK 500 U A2053 C2' - C3' - O3' ANGL. DEV. = 12.9 DEGREES
REMARK 500 PRO K 77 C - N - CD ANGL. DEV. = -19.0 DEGREES
REMARK 500 PRO R 66 C - N - CA ANGL. DEV. = 9.2 DEGREES
REMARK 500 PRO R 66 C - N - CD ANGL. DEV. = -12.9 DEGREES
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: TORSION ANGLES
REMARK 500
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)
REMARK 500
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400
REMARK 500
REMARK 500 M RES CSSEQI PSI PHI
REMARK 500 LYS B 26 79.34 -118.81
REMARK 500 ALA B 57 -47.85 81.56
REMARK 500 LEU B 70 -56.51 58.20
REMARK 500 GLN B 79 54.20 -99.78
REMARK 500 HIS B 81 -174.36 -64.07
REMARK 500 LYS B 82 107.33 64.48
REMARK 500 ILE B 84 117.53 15.58
REMARK 500 ASP B 89 -62.23 -101.79
REMARK 500 ASN B 93 -72.58 31.62
REMARK 500 ARG B 94 28.49 -144.31
REMARK 500 THR B 98 133.02 74.91
REMARK 500 CYS B 101 -62.77 -99.93
REMARK 500 THR B 106 80.15 66.17
REMARK 500 ARG B 107 -28.62 -38.64
REMARK 500 LYS B 116 -83.59 -71.46
REMARK 500 ASN B 132 41.69 75.50
REMARK 500 PHE B 138 82.86 48.72
REMARK 500 ARG B 146 80.28 45.67
REMARK 500 GLN B 147 -69.51 30.63
REMARK 500 THR B 150 -66.90 69.27
REMARK 500 CYS B 154 51.76 -119.33
REMARK 500 LYS B 178 -53.49 -28.66
REMARK 500 VAL B 179 -99.71 -176.02
REMARK 500 GLN B 208 -163.88 -117.93
REMARK 500 ASN B 209 105.82 -33.32
REMARK 500 CYS C 20 -128.93 -72.91
REMARK 500 LYS C 21 16.35 -151.52
REMARK 500 ASN C 28 115.73 76.76
REMARK 500 GLU C 30 105.81 64.00
REMARK 500 LEU C 50 -49.83 77.68
REMARK 500 ASP C 72 50.62 -101.52
REMARK 500 THR C 93 -158.46 -73.58
REMARK 500 ALA C 95 137.75 0.12
REMARK 500 ILE C 98 -63.94 -101.72
REMARK 500 ALA C 99 115.11 66.09
REMARK 500 LYS C 114 47.75 -102.35
REMARK 500 PHE C 115 -86.31 -67.88
REMARK 500 THR C 116 93.38 59.94
REMARK 500 ASP C 129 44.57 -92.48
REMARK 500 ASN C 140 55.52 39.08
REMARK 500 VAL C 143 112.16 66.28
REMARK 500 HIS C 155 -13.49 76.84
REMARK 500 CYS C 162 -143.31 -143.83
REMARK 500 SER C 191 -46.51 80.95
REMARK 500 ASP C 199 -43.81 100.37
REMARK 500 SER D 35 -70.14 -147.72
REMARK 500 VAL D 116 -69.16 65.01
REMARK 500 SER D 130 4.03 -69.05
REMARK 500 LYS D 142 -74.73 -74.88
REMARK 500 LEU D 143 92.11 58.44
REMARK 500
REMARK 500 THIS ENTRY HAS 365 RAMACHANDRAN OUTLIERS.
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: NON-CIS, NON-TRANS
REMARK 500
REMARK 500 THE FOLLOWING PEPTIDE BONDS DEVIATE SIGNIFICANTLY FROM BOTH
REMARK 500 CIS AND TRANS CONFORMATION. CIS BONDS, IF ANY, ARE LISTED
REMARK 500 ON CISPEP RECORDS. TRANS IS DEFINED AS 180 +/- 30 AND
REMARK 500 CIS IS DEFINED AS 0 +/- 30 DEGREES.
REMARK 500 MODEL OMEGA
REMARK 500 ASN B 148 GLN B 149 -148.83
REMARK 500 SER J 132 PRO J 133 148.68
REMARK 500 ILE K 27 ARG K 28 -149.95
REMARK 500 SER K 76 PRO K 77 -128.59
REMARK 500 LEU K 94 PRO K 95 -147.81
REMARK 500 LYS L 164 SER L 165 -148.53
REMARK 500 LYS S 36 GLY S 37 148.78
REMARK 500 LYS U 104 ASN U 105 -149.10
REMARK 500 LYS X 38 ALA X 39 -149.10
REMARK 500 LYS 1 118 VAL 1 119 135.62
REMARK 500
REMARK 500 REMARK: NULL
REMARK 620
REMARK 620 METAL COORDINATION
REMARK 620 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 620 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE):
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG A2155 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 A A 169 OP1
REMARK 620 2 C A 170 OP2 104.0
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG A2104 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 U A 103 OP2
REMARK 620 2 C A 367 OP2 151.1
REMARK 620 3 A A 102 OP2 76.9 78.7
REMARK 620 N 1 2
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG A2151 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 A A2054 OP2
REMARK 620 2 A A2055 OP2 94.6
REMARK 620 3 G A2060 OP2 78.2 69.2
REMARK 620 N 1 2
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG A2164 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 C A1306 OP2
REMARK 620 2 G A1701 O6 139.6
REMARK 620 3 U A1307 O4 91.7 85.5
REMARK 620 4 A A1305 OP1 118.2 97.8 67.5
REMARK 620 N 1 2 3
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG A2146 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 G A1211 OP2
REMARK 620 2 G A1210 OP1 98.4
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG A2149 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 U A2063 OP1
REMARK 620 2 G A2060 OP1 149.4
REMARK 620 3 A A2055 OP1 69.8 83.4
REMARK 620 N 1 2
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG A2148 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 U A1927 OP1
REMARK 620 2 G A2085 OP1 164.3
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG A2162 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 G A1430 OP2
REMARK 620 2 G A1432 O6 146.7
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG A2128 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 A A 628 OP2
REMARK 620 2 A A 627 OP2 78.2
REMARK 620 3 A A 626 OP2 161.8 85.0
REMARK 620 N 1 2
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG A2147 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 A A1261 OP2
REMARK 620 2 G A1876 OP1 130.3
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG A2163 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 C A1375 OP2
REMARK 620 2 G A1674 OP2 103.3
REMARK 620 3 G A1374 O2' 63.5 142.8
REMARK 620 N 1 2
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG A2159 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 G A1063 OP2
REMARK 620 2 A A1074 OP2 153.5
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG A2157 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 A A 562 OP2
REMARK 620 2 A A 563 OP2 70.7
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG A2119 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 A A 466 OP2
REMARK 620 2 G A 467 OP2 88.3
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG A2116 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 U A 385 OP2
REMARK 620 2 A A 384 OP2 78.4
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG A2130 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 C A 632 OP1
REMARK 620 2 C A 630 OP2 111.4
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG A2132 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 A A 642 OP1
REMARK 620 2 A A 643 OP2 87.6
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG A2126 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 A A 612 OP1
REMARK 620 2 A A 614 OP1 81.3
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG A2139 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 G A 964 O6
REMARK 620 2 U A 986 O4 74.5
REMARK 620 3 A A 984 OP2 153.8 81.3
REMARK 620 4 G A 983 O3' 153.3 132.1 51.2
REMARK 620 N 1 2 3
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG A2165 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 A A1304 OP2
REMARK 620 2 A A1303 OP1 67.9
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 ZN T 100 ZN
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 CYS T 40 SG
REMARK 620 2 CYS T 37 SG 84.0
REMARK 620 3 CYS T 22 SG 85.1 157.5
REMARK 620 4 CYS T 19 SG 108.9 89.0 113.2
REMARK 620 N 1 2 3
REMARK 800
REMARK 800 SITE
REMARK 800 SITE_IDENTIFIER: AC1
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2101
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC2
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2102
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC3
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2103
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC4
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2104
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC5
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2105
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC6
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2106
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC7
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2107
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC8
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2108
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC9
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2109
REMARK 800
REMARK 800 SITE_IDENTIFIER: BC1
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2111
REMARK 800
REMARK 800 SITE_IDENTIFIER: BC2
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2112
REMARK 800
REMARK 800 SITE_IDENTIFIER: BC3
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2113
REMARK 800
REMARK 800 SITE_IDENTIFIER: BC4
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2114
REMARK 800
REMARK 800 SITE_IDENTIFIER: BC5
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2115
REMARK 800
REMARK 800 SITE_IDENTIFIER: BC6
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2116
REMARK 800
REMARK 800 SITE_IDENTIFIER: BC7
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2117
REMARK 800
REMARK 800 SITE_IDENTIFIER: BC8
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2118
REMARK 800
REMARK 800 SITE_IDENTIFIER: BC9
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2119
REMARK 800
REMARK 800 SITE_IDENTIFIER: CC1
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2120
REMARK 800
REMARK 800 SITE_IDENTIFIER: CC2
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2121
REMARK 800
REMARK 800 SITE_IDENTIFIER: CC3
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2123
REMARK 800
REMARK 800 SITE_IDENTIFIER: CC4
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2124
REMARK 800
REMARK 800 SITE_IDENTIFIER: CC5
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2125
REMARK 800
REMARK 800 SITE_IDENTIFIER: CC6
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2126
REMARK 800
REMARK 800 SITE_IDENTIFIER: CC7
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2127
REMARK 800
REMARK 800 SITE_IDENTIFIER: CC8
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2128
REMARK 800
REMARK 800 SITE_IDENTIFIER: CC9
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2129
REMARK 800
REMARK 800 SITE_IDENTIFIER: DC1
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2130
REMARK 800
REMARK 800 SITE_IDENTIFIER: DC2
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2131
REMARK 800
REMARK 800 SITE_IDENTIFIER: DC3
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2132
REMARK 800
REMARK 800 SITE_IDENTIFIER: DC4
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2133
REMARK 800
REMARK 800 SITE_IDENTIFIER: DC5
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2135
REMARK 800
REMARK 800 SITE_IDENTIFIER: DC6
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2136
REMARK 800
REMARK 800 SITE_IDENTIFIER: DC7
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2137
REMARK 800
REMARK 800 SITE_IDENTIFIER: DC8
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2138
REMARK 800
REMARK 800 SITE_IDENTIFIER: DC9
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2139
REMARK 800
REMARK 800 SITE_IDENTIFIER: EC1
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2140
REMARK 800
REMARK 800 SITE_IDENTIFIER: EC2
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2141
REMARK 800
REMARK 800 SITE_IDENTIFIER: EC3
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2142
REMARK 800
REMARK 800 SITE_IDENTIFIER: EC4
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2143
REMARK 800
REMARK 800 SITE_IDENTIFIER: EC5
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2144
REMARK 800
REMARK 800 SITE_IDENTIFIER: EC6
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2145
REMARK 800
REMARK 800 SITE_IDENTIFIER: EC7
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2146
REMARK 800
REMARK 800 SITE_IDENTIFIER: EC8
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2147
REMARK 800
REMARK 800 SITE_IDENTIFIER: EC9
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2148
REMARK 800
REMARK 800 SITE_IDENTIFIER: FC1
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2149
REMARK 800
REMARK 800 SITE_IDENTIFIER: FC2
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2150
REMARK 800
REMARK 800 SITE_IDENTIFIER: FC3
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2151
REMARK 800
REMARK 800 SITE_IDENTIFIER: FC4
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2152
REMARK 800
REMARK 800 SITE_IDENTIFIER: FC5
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2153
REMARK 800
REMARK 800 SITE_IDENTIFIER: FC6
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2154
REMARK 800
REMARK 800 SITE_IDENTIFIER: FC7
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2155
REMARK 800
REMARK 800 SITE_IDENTIFIER: FC8
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2156
REMARK 800
REMARK 800 SITE_IDENTIFIER: FC9
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2157
REMARK 800
REMARK 800 SITE_IDENTIFIER: GC1
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2158
REMARK 800
REMARK 800 SITE_IDENTIFIER: GC2
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2159
REMARK 800
REMARK 800 SITE_IDENTIFIER: GC3
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2160
REMARK 800
REMARK 800 SITE_IDENTIFIER: GC4
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2161
REMARK 800
REMARK 800 SITE_IDENTIFIER: GC5
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2162
REMARK 800
REMARK 800 SITE_IDENTIFIER: GC6
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2163
REMARK 800
REMARK 800 SITE_IDENTIFIER: GC7
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2164
REMARK 800
REMARK 800 SITE_IDENTIFIER: GC8
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2165
REMARK 800
REMARK 800 SITE_IDENTIFIER: GC9
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2166
REMARK 800
REMARK 800 SITE_IDENTIFIER: HC1
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG A 2167
REMARK 800
REMARK 800 SITE_IDENTIFIER: HC2
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE 34G A 2168
REMARK 800
REMARK 800 SITE_IDENTIFIER: HC3
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN T 100
REMARK 900
REMARK 900 RELATED ENTRIES
REMARK 900 RELATED ID: EMD-2660 RELATED DB: EMDB
REMARK 900 CRYO-EM STRUCTURE OF THE PLASMODIUM FALCIPARUM 80S RIBOSOME BOUND
REMARK 900 TO THE ANTI-PROTOZOAN DRUG EMETINE
REMARK 900 RELATED ID: EMD-2661 RELATED DB: EMDB
REMARK 900 CRYO-EM STRUCTURE OF THE PLASMODIUM FALCIPARUM 80S RIBOSOME
REMARK 900 RELATED ID: 3J79 RELATED DB: PDB
REMARK 900 CRYO-EM STRUCTURE OF THE PLASMODIUM FALCIPARUM 80S RIBOSOME BOUND
REMARK 900 TO THE ANTI-PROTOZOAN DRUG EMETINE, LARGE SUBUNIT
DBREF 3J7A B 1 262 UNP O97313 RS3A_PLAF7 1 262
DBREF 3J7A C 1 263 UNP Q8IJD4 RSSA_PLAF7 1 263
DBREF 3J7A D 1 225 UNP Q8IKH8 Q8IKH8_PLAF7 1 221
DBREF 3J7A E 1 189 UNP Q8I3R0 Q8I3R0_PLAF7 1 189
DBREF 3J7A F 1 261 UNP Q8IIU8 Q8IIU8_PLAF7 1 261
DBREF 3J7A G 1 272 UNP Q8IL02 Q8IL02_PLAF7 1 272
DBREF 3J7A H 1 306 UNP Q8IDR9 Q8IDR9_PLAF7 1 306
DBREF 3J7A I 1 195 UNP Q8IBN5 Q8IBN5_PLAF7 1 195
DBREF 3J7A J 1 194 UNP Q8IET7 Q8IET7_PLAF7 1 194
DBREF 3J7A K 1 130 UNP O77395 O77395_PLAF7 1 130
DBREF 3J7A L 1 218 UNP Q8IM10 Q8IM10_PLAF7 1 218
DBREF 3J7A M 1 144 UNP Q8IAX5 Q8IAX5_PLAF7 1 144
DBREF 3J7A N 1 118 UNP Q8IK02 Q8IK02_PLAF7 1 118
DBREF 3J7A O 1 137 UNP Q8IBQ5 Q8IBQ5_PLAF7 1 137
DBREF 3J7A P 1 151 UNP Q8I3U6 Q8I3U6_PLAF7 1 151
DBREF 3J7A Q 1 145 UNP O97248 O97248_PLAF7 1 145
DBREF 3J7A R 1 141 UNP O97249 RS12_PLAF7 1 141
DBREF 3J7A S 1 156 UNP Q8IIA2 Q8IIA2_PLAF7 1 156
DBREF 3J7A T 1 54 UNP C0H4K8 C0H4K8_PLAF7 1 54
DBREF 3J7A U 1 151 UNP Q8IDB0 Q8IDB0_PLAF7 1 151
DBREF 3J7A V 1 161 UNP O77381 O77381_PLAF7 1 161
DBREF 3J7A W 1 137 UNP Q8I502 Q8I502_PLAF7 1 137
DBREF 3J7A X 1 145 UNP C0H5C2 C0H5C2_PLAF7 1 145
DBREF 3J7A Y 1 170 UNP Q8IFP2 Q8IFP2_PLAF7 1 170
DBREF 3J7A Z 1 82 UNP Q8IHS5 Q8IHS5_PLAF7 1 82
DBREF 3J7A 1 1 133 UNP Q8I3R6 Q8I3R6_PLAF7 1 133
DBREF 3J7A 2 1 105 UNP Q8ILN8 Q8ILN8_PLAF7 1 105
DBREF 3J7A 3 1 107 UNP O96258 O96258_PLAF7 1 107
DBREF 3J7A 4 1 82 UNP Q8IEN2 Q8IEN2_PLAF7 1 82
DBREF 3J7A 5 1 67 UNP Q8IKL9 Q8IKL9_PLAF7 1 67
DBREF 3J7A 6 1 58 UNP O96269 RS30_PLAF7 1 58
DBREF 3J7A A 1 2092 PDB 3J7A 3J7A 1 2092
DBREF 3J7A 7 1 74 PDB 3J7A 3J7A 1 74
SEQRES 1 A 2092 A A C C U G G U U G A U C
SEQRES 2 A 2092 U U G C C A G U A G U C A
SEQRES 3 A 2092 U A U G C U U G U C U C A
SEQRES 4 A 2092 A A G A U U A A G C C A U
SEQRES 5 A 2092 G C A A G U G A A A G U A
SEQRES 6 A 2092 U A U A U A U A U U U U A
SEQRES 7 A 2092 U A U G U A G A A A C U G
SEQRES 8 A 2092 C G A A C G G C U C A U U
SEQRES 9 A 2092 A A A A C A G U U A U A G
SEQRES 10 A 2092 U C U A C U U G A C A U U
SEQRES 11 A 2092 U U U A U U A U A A G G A
SEQRES 12 A 2092 U A A C U A C G G A A A A
SEQRES 13 A 2092 G C U G U A G C U A A U A
SEQRES 14 A 2092 C U U G C U U U A U U A U
SEQRES 15 A 2092 C C U U U G A U U U U U A
SEQRES 16 A 2092 U C U U U G G A U A A G U
SEQRES 17 A 2092 A U U U G U U A G G C C U
SEQRES 18 A 2092 U A U A A G A A A A A A G
SEQRES 19 A 2092 U U A U U A A C U U A A G
SEQRES 20 A 2092 G A A U U A U A A C A A A
SEQRES 21 A 2092 G A A G U A A C A C G U A
SEQRES 22 A 2092 A U A A A U U U A U U U U
SEQRES 23 A 2092 A U U U A G U G U G U A U
SEQRES 24 A 2092 C A A U C G A G U U U C U
SEQRES 25 A 2092 G A C C U A U C A G C U U
SEQRES 26 A 2092 U U G A U G U U A G G G U
SEQRES 27 A 2092 A U U G G C C U A A C A U
SEQRES 28 A 2092 G G C U A U G A C G G G U
SEQRES 29 A 2092 A A C G G G G A A U U A G
SEQRES 30 A 2092 A G U U C G A U U C C G G
SEQRES 31 A 2092 A G A G G G A G C C U G A
SEQRES 32 A 2092 G A A A U A G C U A C C A
SEQRES 33 A 2092 C A U C U A A G G A A G G
SEQRES 34 A 2092 C A G C A G G C G C G U A
SEQRES 35 A 2092 A A U U A C C C A A U U C
SEQRES 36 A 2092 U A A A G A A G A G A G G
SEQRES 37 A 2092 U A G U G A C A A G A A A
SEQRES 38 A 2092 U A A C A A U G C A A G G
SEQRES 39 A 2092 C C A A U U U U U G G U U
SEQRES 40 A 2092 U U G U A A U U G G A A U
SEQRES 41 A 2092 G G U G G G A A U U U A A
SEQRES 42 A 2092 A A C C U U C C C A G A G
SEQRES 43 A 2092 U A A C A A U U G G A G G
SEQRES 44 A 2092 G C A A G U C U G G U G C
SEQRES 45 A 2092 C A G C A G C C G C G G U
SEQRES 46 A 2092 A A U U C C A G C U C C A
SEQRES 47 A 2092 A U A G C G U A U A U U A
SEQRES 48 A 2092 A A A U U G U U G C A G U
SEQRES 49 A 2092 U A A A A C G C U C G U A
SEQRES 50 A 2092 G U U G A A U U U C A A A
SEQRES 51 A 2092 G A A U C G A U A U U U U
SEQRES 52 A 2092 A U U G U A A C U A U U C
SEQRES 53 A 2092 U A G G G G A A C U A U U
SEQRES 54 A 2092 U U A G C U U U U C G C U
SEQRES 55 A 2092 U U A A U A C G C U U C C
SEQRES 56 A 2092 U C U A U U A U U A U G U
SEQRES 57 A 2092 U C U U U A A A U A A C A
SEQRES 58 A 2092 A A G A U U C U U U U U A
SEQRES 59 A 2092 A A A U C C C C A C U U U
SEQRES 60 A 2092 U G C U U U U G C U U U U
SEQRES 61 A 2092 U U U G G G G A U U U U G
SEQRES 62 A 2092 U U A C U U U G A G U A A
SEQRES 63 A 2092 A U U A G A G U G U U C A
SEQRES 64 A 2092 A A G C A A A C A G U U A
SEQRES 65 A 2092 A A G C A U U U A C U G U
SEQRES 66 A 2092 G U U U G A A U A C U A U
SEQRES 67 A 2092 A G C A U G G A A U A A C
SEQRES 68 A 2092 A A A A U U G A A C A A G
SEQRES 69 A 2092 C U A A A A U U U U U U G
SEQRES 70 A 2092 U U C U U U U U U C U U A
SEQRES 71 A 2092 U U U U G G C U U A G U U
SEQRES 72 A 2092 A C G A U U A A U A G G A
SEQRES 73 A 2092 G U A G C U U G G G G A C
SEQRES 74 A 2092 A U U C G U A U U C A G A
SEQRES 75 A 2092 U G U C A G A G G U G A A
SEQRES 76 A 2092 A U U C U U A G A U U U U
SEQRES 77 A 2092 C U G G A G A C G A A C A
SEQRES 78 A 2092 A C U G C G A A A G C A U
SEQRES 79 A 2092 U U G U C U A A A A U A C
SEQRES 80 A 2092 U U C C A U U A A U C A A
SEQRES 81 A 2092 G A A C G A A A G U U A A
SEQRES 82 A 2092 G G G A G U G A A G A C G
SEQRES 83 A 2092 A U C A G A U A C C G U C
SEQRES 84 A 2092 G U A A U C U U A A C C A
SEQRES 85 A 2092 U A A A C U A U G C C G A
SEQRES 86 A 2092 C U A G G U G U U G G A U
SEQRES 87 A 2092 G A A A G U G U U A A A A
SEQRES 88 A 2092 A U A A A A G U C A U C U
SEQRES 89 A 2092 U U C G A G G U G A C U U
SEQRES 90 A 2092 U U A G A U U G C U U C C
SEQRES 91 A 2092 U U C A G U A C C U U A U
SEQRES 92 A 2092 G A G A A A U C A A A G U
SEQRES 93 A 2092 C U U U G G G U U C U G G
SEQRES 94 A 2092 G G C G A G U A U U C G C
SEQRES 95 A 2092 G C A A G C G A G A A A G
SEQRES 96 A 2092 U U A A A A G A A U U G A
SEQRES 97 A 2092 C G G A A G G G C A C C A
SEQRES 98 A 2092 C C A G G C G U G G A G C
SEQRES 99 A 2092 U U G C G G C U U A A U U
SEQRES 100 A 2092 U G A C U C A A C A C G G
SEQRES 101 A 2092 G G A A A C U C A C U A G
SEQRES 102 A 2092 U U U A A G A C A A G A G
SEQRES 103 A 2092 U A G G A U U G A C A G A
SEQRES 104 A 2092 U U A A U A G C U C U U U
SEQRES 105 A 2092 C U U G A U U U C U U G G
SEQRES 106 A 2092 A U G G U G A U G C A U G
SEQRES 107 A 2092 G C C G U U U U U A G U U
SEQRES 108 A 2092 C G U G A A U A U G A U U
SEQRES 109 A 2092 U G U C U G G U U A A U U
SEQRES 110 A 2092 C C G A U A A C G A A C G
SEQRES 111 A 2092 A G A U C U U A A C C U G
SEQRES 112 A 2092 C U A A U U A G C G G C G
SEQRES 113 A 2092 A G U A C A C U A U A U U
SEQRES 114 A 2092 C U U A U U U G A A A U U
SEQRES 115 A 2092 G A A C A U A G G U A A C
SEQRES 116 A 2092 U A U A C A U U U A U U C
SEQRES 117 A 2092 A G U A A U C A A A U U A
SEQRES 118 A 2092 G G A U A U U U U U A U U
SEQRES 119 A 2092 A A A A U A U C C U U U U
SEQRES 120 A 2092 C C C U G U U C U A C U A
SEQRES 121 A 2092 A U A A U U U G U U U U U
SEQRES 122 A 2092 U A C U C U A U U U C U C
SEQRES 123 A 2092 U C U U C U U U U A A G A
SEQRES 124 A 2092 A U G U A C U U G C U U G
SEQRES 125 A 2092 A U U G A A A A G C U U C
SEQRES 126 A 2092 U U A G A G G A A C A U U
SEQRES 127 A 2092 G U G U G U C U A A C A C
SEQRES 128 A 2092 A A G G A A G U U U A A G
SEQRES 129 A 2092 G C A A C A A C A G G U C
SEQRES 130 A 2092 U G U G A U G U C C U U A
SEQRES 131 A 2092 G A U G A A C U A G G C U
SEQRES 132 A 2092 G C A C G C G U G C U A C
SEQRES 133 A 2092 A C U G A U A U A U A U A
SEQRES 134 A 2092 A C G A G U U U U U A A A
SEQRES 135 A 2092 A A U A U G C U U A U A U
SEQRES 136 A 2092 U U G U A U C U U U G A U
SEQRES 137 A 2092 G C U U A U A U U U U G C
SEQRES 138 A 2092 A U A C U U U U C C U C C
SEQRES 139 A 2092 G C C G A A A G G C G U A
SEQRES 140 A 2092 G G U A A U C U U U A U C
SEQRES 141 A 2092 A A U A U A U A U C G U G
SEQRES 142 A 2092 A U G G G G A U A G A U U
SEQRES 143 A 2092 A U U G C A A U U A U U A
SEQRES 144 A 2092 A U C U U G A A C G A G G
SEQRES 145 A 2092 A A U G C C U A G U A A G
SEQRES 146 A 2092 C A U G A U U C A U C A G
SEQRES 147 A 2092 A U U G U G C U G A C U A
SEQRES 148 A 2092 C G U C C C U G C C C U U
SEQRES 149 A 2092 U G U A C A C A C C G C C
SEQRES 150 A 2092 C G U C G C U C C U A C C
SEQRES 151 A 2092 G A U U G A A A G A U A U
SEQRES 152 A 2092 G A U G A A U U G U U U G
SEQRES 153 A 2092 G A C A A G A A A A A U U
SEQRES 154 A 2092 G A A U U A U A U U C U U
SEQRES 155 A 2092 U U U U U U C U G G A A A
SEQRES 156 A 2092 A A C C G U A A A U C C U
SEQRES 157 A 2092 A U C U U U U A A A G G A
SEQRES 158 A 2092 A G G A G A A G U C G U A
SEQRES 159 A 2092 A C A A G G U U U C C G U
SEQRES 160 A 2092 A G G U G A A C C U G C G
SEQRES 161 A 2092 G A A G G A U C A U U A
SEQRES 1 B 262 MET ALA VAL GLY LYS ASN LYS ARG THR SER LYS GLY LYS
SEQRES 2 B 262 LYS GLY GLY LYS LYS LYS VAL THR ASP VAL PHE THR LYS
SEQRES 3 B 262 LYS GLU TRP TYR ASP LEU LYS ALA PRO LYS MET PHE LEU
SEQRES 4 B 262 VAL ARG ASN PHE GLY LYS THR LEU VAL THR LYS THR ILE
SEQRES 5 B 262 GLY LYS LYS LEU ALA THR ASP SER LEU LYS GLY ARG ILE
SEQRES 6 B 262 TYR GLU VAL ASN LEU ALA ASP LEU ASN ASN ASP GLU ASP
SEQRES 7 B 262 GLN ALA HIS LYS LYS ILE LYS LEU SER CYS ASP HIS ILE
SEQRES 8 B 262 ILE ASN ARG ASP CYS TYR THR ASP PHE CYS GLY LEU SER
SEQRES 9 B 262 ILE THR ARG ASP LYS LEU CYS SER LEU ILE ARG LYS GLY
SEQRES 10 B 262 TYR THR LEU ILE GLU GLY HIS THR ASP VAL LYS THR LEU
SEQRES 11 B 262 ASP ASN TYR HIS LEU ARG MET PHE CYS ILE ALA PHE THR
SEQRES 12 B 262 LYS LYS ARG GLN ASN GLN THR LYS SER THR CYS TYR ALA
SEQRES 13 B 262 GLN THR SER GLN ILE LYS LYS ILE ARG LYS LYS MET VAL
SEQRES 14 B 262 ASP ILE MET THR ALA GLU ALA SER LYS VAL LEU LEU LYS
SEQRES 15 B 262 ASP LEU VAL LYS LYS PHE ILE PRO GLU SER ILE GLY LYS
SEQRES 16 B 262 GLU ILE GLU LYS GLN CYS LYS LYS ILE TYR PRO LEU GLN
SEQRES 17 B 262 ASN VAL LEU ILE ARG LYS VAL LYS ILE LEU LYS ARG PRO
SEQRES 18 B 262 LYS LEU ASP ILE SER LYS LEU MET GLU LEU HIS THR ASP
SEQRES 19 B 262 PRO LYS GLU GLU SER GLY LYS ASN VAL ASN ALA LEU PRO
SEQRES 20 B 262 GLU SER LYS GLU ALA THR ASN ILE LEU THR ALA GLU LEU
SEQRES 21 B 262 LYS HIS
SEQRES 1 C 263 MET SER ASN LYS LYS GLY GLN SER PRO LYS GLU GLU SER
SEQRES 2 C 263 ILE ALA LYS MET LEU ILE CYS LYS VAL HIS ILE GLY THR
SEQRES 3 C 263 LYS ASN LEU GLU ASN LYS MET LYS ARG TYR VAL TYR THR
SEQRES 4 C 263 ARG ALA LYS ASP GLY VAL HIS ILE ILE ASN LEU ALA LYS
SEQRES 5 C 263 THR TYR GLU LYS LEU GLN LEU ALA ALA ARG ILE ILE VAL
SEQRES 6 C 263 ALA ILE SER ASN PRO ALA ASP VAL VAL VAL VAL SER ALA
SEQRES 7 C 263 ARG PRO PHE GLY SER ARG ALA VAL LEU LYS PHE ALA GLN
SEQRES 8 C 263 TYR THR GLY ALA GLN ALA ILE ALA GLY ARG TRP THR PRO
SEQRES 9 C 263 GLY MET LEU THR ASN GLN ILE ILE GLN LYS PHE THR GLU
SEQRES 10 C 263 PRO ARG LEU LEU ILE VAL THR ASP PRO ARG THR ASP ALA
SEQRES 11 C 263 GLN SER VAL LYS GLU SER ALA TYR ALA ASN ILE PRO VAL
SEQRES 12 C 263 ILE ALA LEU CYS ASP SER ASP SER PRO LEU GLU HIS VAL
SEQRES 13 C 263 ASP ILE ALA ILE PRO CYS ASN ASN LYS GLY LYS GLU SER
SEQRES 14 C 263 ILE ALA LEU MET TYR TRP LEU LEU ALA GLN GLU VAL LEU
SEQRES 15 C 263 TYR LEU LYS GLY VAL ILE PRO ARG SER GLU PRO TRP ASN
SEQRES 16 C 263 VAL MET VAL ASP MET PHE LEU TRP ARG ASP PRO GLU GLN
SEQRES 17 C 263 PHE GLU LEU LYS ASN LEU ALA ASN GLU GLU ASN THR PRO
SEQRES 18 C 263 THR ALA PRO HIS LEU ILE GLU ASN GLN TYR ALA ALA GLU
SEQRES 19 C 263 ALA PRO TYR ASP GLU TRP THR LYS LYS GLU GLU TRP ASN
SEQRES 20 C 263 ASP ASN THR ASN GLU ASP TRP LYS ASN PRO ILE ALA ALA
SEQRES 21 C 263 GLU GLU TRP
SEQRES 1 D 221 MET SER ALA PRO ILE SER LYS LYS ARG LYS PHE ILE ASN
SEQRES 2 D 221 ASP GLY VAL PHE GLN ALA GLU LEU ASN GLU PHE LEU ALA
SEQRES 3 D 221 ARG ILE LEU ALA GLU ASP GLY TYR SER GLY VAL GLU VAL
SEQRES 4 D 221 ARG VAL THR PRO ILE ARG THR GLU VAL ILE ILE ARG ALA
SEQRES 5 D 221 THR ARG THR ARG GLU VAL LEU GLY ASP LYS GLY ARG ARG
SEQRES 6 D 221 ILE ARG GLU LEU THR SER LEU VAL GLN LYS ARG PHE PHE
SEQRES 7 D 221 ASN LYS SER THR ASN SER VAL GLU LEU PHE ALA GLU ARG
SEQRES 8 D 221 VAL GLU HIS ARG GLY LEU CYS ALA MET ALA GLN ALA GLU
SEQRES 9 D 221 SER LEU ARG TYR LYS LEU LEU LYS GLY LEU ALA VAL ARG
SEQRES 10 D 221 ARG ALA CYS TYR GLY VAL LEU ARG HIS ILE MET GLU SER
SEQRES 11 D 221 GLY ALA LYS GLY CYS GLU VAL ILE VAL SER GLY LYS LEU
SEQRES 12 D 221 ARG ALA GLN ARG ALA LYS SER MET LYS PHE ARG ASP GLY
SEQRES 13 D 221 TYR LEU ILE SER THR GLY GLU PRO SER LYS ARG PHE VAL
SEQRES 14 D 221 ASN THR ALA THR ARG SER ALA GLN LEU LYS GLN GLY VAL
SEQRES 15 D 221 LEU GLY ILE LYS VAL LYS ILE MET LEU PRO THR ALA ILE
SEQRES 16 D 221 ASP THR ARG THR GLY LEU THR SER ILE LEU PRO ASP ASN
SEQRES 17 D 221 ILE SER VAL LEU GLU PRO LYS THR ASP THR VAL ASP LEU
SEQRES 1 E 189 MET PRO LYS SER TYR ARG ASN TYR SER LYS THR ALA ARG
SEQRES 2 E 189 ASN PRO LYS ARG PRO PHE GLU LYS GLU ARG LEU ASP GLN
SEQRES 3 E 189 GLU LEU LYS LEU ILE GLY GLU TYR GLY LEU LYS ASN LYS
SEQRES 4 E 189 ARG GLU ILE TRP ARG VAL GLN TYR LEU LEU ALA LYS ILE
SEQRES 5 E 189 ARG SER ALA ALA ARG TYR LEU LEU THR LEU ASP GLU LYS
SEQRES 6 E 189 SER SER LYS ARG ILE PHE GLN GLY GLU ALA LEU LEU ARG
SEQRES 7 E 189 ARG MET VAL ARG GLN GLY LEU LEU GLY GLU ASN GLU GLU
SEQRES 8 E 189 LYS LEU ASP TYR VAL LEU GLY LEU THR LEU PRO LYS LEU
SEQRES 9 E 189 LEU GLU ARG ARG LEU GLN THR LYS VAL PHE LYS LEU GLY
SEQRES 10 E 189 LEU ALA LYS SER VAL HIS HIS ALA ARG VAL LEU ILE ARG
SEQRES 11 E 189 GLN ARG HIS ILE ARG VAL GLY LYS GLN MET VAL ASP ILE
SEQRES 12 E 189 PRO SER PHE LEU VAL ARG VAL ASP SER GLU LYS HIS ILE
SEQRES 13 E 189 ASP PHE ALA THR THR SER PRO PHE GLY GLY ALA ARG PRO
SEQRES 14 E 189 GLY ARG VAL LYS ARG LYS SER LEU LYS LYS GLN LYS GLU
SEQRES 15 E 189 LYS THR GLU ALA GLU ALA GLU
SEQRES 1 F 261 MET GLY LYS GLY ILE LYS LYS HIS LEU LYS ARG VAL ASN
SEQRES 2 F 261 ALA PRO SER HIS TRP MET LEU ASN LYS MET GLY GLY GLN
SEQRES 3 F 261 TYR ALA PRO LYS THR SER SER GLY PRO HIS LYS LEU LEU
SEQRES 4 F 261 GLU SER ILE PRO LEU VAL ILE LEU LEU ARG ASN ARG LEU
SEQRES 5 F 261 LYS TYR ALA LEU THR PHE ASP GLU VAL LYS MET ILE LEU
SEQRES 6 F 261 ILE GLN LYS ILE VAL LYS VAL ASP ASN LYS VAL ARG THR
SEQRES 7 F 261 ASP CYS THR PHE PRO VAL GLY LEU MET ASP VAL ILE HIS
SEQRES 8 F 261 ILE THR LYS SER ASN GLU TYR PHE ARG LEU LEU TYR ASP
SEQRES 9 F 261 ILE LYS GLY ARG PHE VAL PRO HIS ARG ILE THR ASN GLU
SEQRES 10 F 261 GLU SER LYS TYR LYS LEU CYS LYS VAL LYS LYS ILE LEU
SEQRES 11 F 261 LEU ARG LYS GLY ARG LEU SER ILE ALA VAL THR HIS ASP
SEQRES 12 F 261 GLY ARG SER ILE PRO TYR ILE HIS PRO ASP VAL LYS VAL
SEQRES 13 F 261 ASN ASP THR VAL ARG LEU ASP LEU GLU THR GLY LYS VAL
SEQRES 14 F 261 LEU GLU HIS LEU LYS PHE GLN VAL GLY SER LEU VAL MET
SEQRES 15 F 261 VAL THR ALA GLY HIS SER VAL GLY ARG VAL GLY VAL ILE
SEQRES 16 F 261 SER SER ILE ASP LYS ASN MET GLY THR TYR ASP ILE ILE
SEQRES 17 F 261 HIS VAL LYS ASP SER ARG ASN LYS VAL PHE ALA THR ARG
SEQRES 18 F 261 LEU SER ASN VAL PHE VAL ILE GLY ASP ASN THR LYS PRO
SEQRES 19 F 261 TYR ILE SER LEU PRO ARG GLU LYS GLY ILE LYS LEU ASP
SEQRES 20 F 261 ILE ILE GLU GLU ARG ARG ASN ARG LEU LYS ALA LEU ASN
SEQRES 21 F 261 ASN
SEQRES 1 G 272 MET GLU ASP ARG GLY GLY PHE SER ARG GLY PHE GLY ARG
SEQRES 2 G 272 GLY VAL ARG GLY THR ARG GLY ARG GLY GLY ARG GLY ALA
SEQRES 3 G 272 ARG GLY ARG GLY ARG GLY SER ALA GLU ASP ASP LEU LYS
SEQRES 4 G 272 ASN TRP VAL PRO VAL THR LYS LEU GLY ARG LEU VAL LYS
SEQRES 5 G 272 GLU GLY LYS ILE VAL SER ILE GLU GLU ILE TYR LEU HIS
SEQRES 6 G 272 SER LEU PRO ILE LYS GLU TYR GLN ILE ILE ASP TYR PHE
SEQRES 7 G 272 PHE GLN PRO ASN GLU CYS SER HIS PRO LEU LYS ASP ASP
SEQRES 8 G 272 VAL VAL LYS ILE MET PRO VAL GLN LYS GLN THR ARG ALA
SEQRES 9 G 272 GLY GLN ARG THR ARG PHE LYS ALA PHE VAL ALA ILE GLY
SEQRES 10 G 272 ASP GLY ASN GLY HIS CYS GLY LEU GLY VAL LYS CYS ALA
SEQRES 11 G 272 LYS GLU VAL ALA THR ALA ILE ARG GLY ALA ILE ILE SER
SEQRES 12 G 272 ALA LYS LEU SER LEU ILE PRO VAL ARG ARG GLY TYR TRP
SEQRES 13 G 272 GLY ASN LYS ILE GLY ASP PRO HIS THR VAL PRO MET LYS
SEQRES 14 G 272 VAL SER GLY LYS CYS GLY SER VAL ARG ILE ARG LEU VAL
SEQRES 15 G 272 PRO ALA PRO ARG GLY THR GLN ILE VAL GLY ALA PRO THR
SEQRES 16 G 272 THR LYS LYS MET LEU ASN PHE ALA GLY ILE LYS ASP CYS
SEQRES 17 G 272 PHE SER SER SER CYS GLY LYS THR LYS THR LYS GLY ASN
SEQRES 18 G 272 PHE LEU ARG ALA ILE PHE ASN ALA LEU SER LYS THR TYR
SEQRES 19 G 272 GLY TYR LEU THR PRO ASP LEU TRP LYS VAL THR ASN PHE
SEQRES 20 G 272 ASP LYS SER PRO TYR GLU GLU TRP SER ASP PHE LEU GLU
SEQRES 21 G 272 THR TYR GLN ASN LEU LYS GLY ILE LYS GLY THR VAL
SEQRES 1 H 306 MET LYS LEU ASN ILE SER ASN PRO LEU ASN ASN VAL GLN
SEQRES 2 H 306 LYS SER ILE GLU ILE ASP ASP GLU LYS LYS LEU LEU PRO
SEQRES 3 H 306 PHE MET GLU LYS ARG ILE GLY ASN ALA VAL PRO GLY ASP
SEQRES 4 H 306 SER ILE GLY GLU GLU PHE THR GLY TYR VAL PHE ARG ILE
SEQRES 5 H 306 THR GLY GLY ASN ASP LYS GLN GLY PHE PRO MET ILE GLN
SEQRES 6 H 306 GLY VAL LEU THR ASN ASN ARG VAL ARG LEU LEU PHE LYS
SEQRES 7 H 306 LYS GLY MET LYS CYS TYR ARG PRO ARG LYS LYS GLY GLU
SEQRES 8 H 306 ARG LYS ARG LYS SER VAL ARG GLY CYS ILE VAL GLY GLN
SEQRES 9 H 306 ASP LEU SER ALA LEU ASN LEU THR LEU VAL LYS LYS GLY
SEQRES 10 H 306 VAL ASN GLU ILE PRO GLY LEU THR ASP LYS ALA VAL GLY
SEQRES 11 H 306 LYS LYS LEU GLY PRO LYS ARG ALA SER LYS ILE ARG LYS
SEQRES 12 H 306 LEU PHE ASN LEU ASP LYS SER ASP ASP VAL ARG LYS TYR
SEQRES 13 H 306 VAL ILE GLY ARG ALA ILE THR LYS ASN GLY LYS THR LYS
SEQRES 14 H 306 PHE ILE LYS PRO LYS ILE GLN ARG LEU VAL THR GLU LYS
SEQRES 15 H 306 ARG LEU LEU ARG LYS ARG ASN LEU LEU GLN ALA LYS GLU
SEQRES 16 H 306 LYS ARG ARG LEU GLU LYS LYS GLN GLN LEU LYS GLU TYR
SEQRES 17 H 306 LYS GLN LEU LEU ASN LYS TYR ARG SER GLU LEU ASN GLN
SEQRES 18 H 306 GLN HIS ASP VAL GLU THR THR LYS LYS LYS LYS VAL LYS
SEQRES 19 H 306 LYS SER LEU SER LYS THR ASN LYS THR ALA SER LYS SER
SEQRES 20 H 306 LYS LEU ASN THR LYS GLN GLU GLN LYS ASP LYS THR GLU
SEQRES 21 H 306 LYS LYS GLN ASN LYS THR ASN ASN ILE LYS ASN ASP LYS
SEQRES 22 H 306 SER GLU LYS LYS GLU GLN ALA LYS LYS LYS THR LYS THR
SEQRES 23 H 306 ASN GLU ASN THR GLN GLN THR LYS GLN ASN LYS PRO ASP
SEQRES 24 H 306 LYS LYS ASN LYS ALA LYS LYS
SEQRES 1 I 195 MET GLU THR THR THR ALA ASP ILE LYS LEU PHE LYS LYS
SEQRES 2 I 195 TRP SER TYR GLU GLU ILE ASN ILE ALA ASP LEU SER LEU
SEQRES 3 I 195 VAL ASP CYS ILE ALA VAL SER GLN LYS ALA CYS VAL TYR
SEQRES 4 I 195 THR PRO HIS THR ALA GLY ARG TYR GLN LYS LYS ARG PHE
SEQRES 5 I 195 ARG LYS ALA LEU CYS PRO ILE VAL GLU ARG LEU VAL ASN
SEQRES 6 I 195 SER MET MET MET HIS GLY ARG ASN ASN GLY LYS LYS LEU
SEQRES 7 I 195 LYS ALA ILE ARG ILE VAL ALA TYR ALA PHE GLU ILE ILE
SEQRES 8 I 195 HIS LEU MET THR GLY GLU ASN PRO LEU GLN VAL PHE VAL
SEQRES 9 I 195 ASN ALA VAL GLN LYS GLY GLY PRO ARG GLU ASP SER THR
SEQRES 10 I 195 ARG ILE GLY SER ALA GLY VAL VAL ARG ARG GLN ALA VAL
SEQRES 11 I 195 ASP VAL SER PRO LEU ARG ARG VAL ASN GLN ALA ILE TYR
SEQRES 12 I 195 LEU ILE CYS THR GLY ALA ARG ASN ALA ALA PHE ARG ASN
SEQRES 13 I 195 ILE LYS SER ILE SER GLU CYS LEU ALA GLU GLU ILE ILE
SEQRES 14 I 195 ASN CYS ALA ASN GLU SER SER SER SER TYR ALA ILE LYS
SEQRES 15 I 195 LYS LYS ASP GLU ILE GLU ARG VAL ALA LYS ALA ASN ARG
SEQRES 1 J 194 MET ASP ALA VAL GLN LYS ARG VAL LEU LYS SER ASN PRO
SEQRES 2 J 194 SER ASP LEU GLU LYS GLU ILE ALA GLN CYS LEU LEU ASP
SEQRES 3 J 194 ILE GLU LEU SER SER SER SER ASP ILE LYS THR ASP ALA
SEQRES 4 J 194 LYS GLU ILE LYS LEU LEU SER CYS ASP LEU ILE GLU VAL
SEQRES 5 J 194 GLU LYS LEU LYS LYS LYS THR ILE LEU ILE TYR ILE PRO
SEQRES 6 J 194 TYR LYS ILE TYR THR THR TYR VAL ARG LYS ILE GLN ARG
SEQRES 7 J 194 LYS LEU ILE ASN GLU LEU GLU LYS LYS THR LYS LYS TYR
SEQRES 8 J 194 VAL VAL LEU VAL ALA LYS ARG THR ILE LEU LYS GLY LYS
SEQRES 9 J 194 GLN LYS ASN LYS SER PHE LYS ILE ILE PRO ARG SER ARG
SEQRES 10 J 194 THR LEU THR SER VAL TYR ASP SER ILE LEU GLU ASP ILE
SEQRES 11 J 194 VAL SER PRO SER GLU ILE ILE GLY LYS ARG ILE SER MET
SEQRES 12 J 194 LYS ALA ASP GLY LYS ARG VAL PHE LYS ILE MET LEU ASP
SEQRES 13 J 194 SER LYS GLU ARG GLN ARG ASP ASN ILE GLU GLU LYS LEU
SEQRES 14 J 194 ILE SER PHE ALA ALA VAL TYR LYS LYS ILE THR ARG ARG
SEQRES 15 J 194 ASP ALA VAL PHE SER LEU PRO PRO THR ASN GLU LYS
SEQRES 1 K 130 MET VAL ARG MET SER VAL LEU ALA ASP CYS LEU LYS THR
SEQRES 2 K 130 ILE ASN ASN ALA GLU LYS ARG GLY ARG ARG GLN VAL LEU
SEQRES 3 K 130 ILE ARG PRO SER SER LYS VAL VAL ILE LYS PHE LEU GLN
SEQRES 4 K 130 TYR MET GLN LYS LYS GLY TYR ILE GLY SER PHE GLU ILE
SEQRES 5 K 130 VAL ASP ASP HIS ARG SER GLY LYS ILE VAL VAL ASN LEU
SEQRES 6 K 130 LEU GLY ARG ILE ASN LYS CYS ALA VAL ILE SER PRO ARG
SEQRES 7 K 130 TYR ASP VAL LYS LEU ASP GLU ILE GLU LYS ILE ILE THR
SEQRES 8 K 130 SER ILE LEU PRO SER ARG LEU PHE GLY HIS LEU ILE LEU
SEQRES 9 K 130 THR THR PRO TYR GLY ILE MET ASP HIS GLU GLU ALA ARG
SEQRES 10 K 130 ARG LYS HIS THR GLY GLY LYS VAL LEU GLY PHE PHE PHE
SEQRES 1 L 218 MET GLY ILE SER ARG ASP GLY ARG HIS LYS LEU ARG LEU
SEQRES 2 L 218 THR GLY GLY LYS LYS LYS ILE HIS LYS LYS LYS ARG LYS
SEQRES 3 L 218 TYR GLU LEU GLY ARG PRO PRO SER ASN THR LYS LEU GLY
SEQRES 4 L 218 SER ARG GLN VAL HIS VAL VAL ARG GLY ARG GLY ARG ASN
SEQRES 5 L 218 TYR LYS TYR ARG ALA ILE LYS LEU ASP SER GLY SER PHE
SEQRES 6 L 218 SER TRP PRO THR PHE GLY ILE SER LYS ASN THR ARG ILE
SEQRES 7 L 218 ILE ASP VAL VAL TYR ASN ALA SER ASN ASN GLU LEU VAL
SEQRES 8 L 218 ARG THR LYS THR LEU VAL LYS ASN CYS ILE VAL VAL ILE
SEQRES 9 L 218 ASP SER HIS PRO PHE THR THR TRP TYR GLU ASN THR PHE
SEQRES 10 L 218 GLY THR THR LEU GLY LYS LYS LYS LYS GLU LYS LYS GLU
SEQRES 11 L 218 GLU ASP ASN LYS GLU GLU ASN LYS GLN GLU VAL GLU ASN
SEQRES 12 L 218 ASN GLU GLU ALA ALA LYS ASP GLU THR THR LYS THR TYR
SEQRES 13 L 218 GLY VAL ILE LYS LYS ILE GLY LYS SER LYS ASN ILE ASP
SEQRES 14 L 218 PRO LEU LEU LEU GLU GLN PHE LYS GLN GLY ARG VAL LEU
SEQRES 15 L 218 ALA CYS ILE SER SER ARG PRO GLY GLN CYS GLY LYS ALA
SEQRES 16 L 218 ASP GLY TYR ILE ILE GLU GLY ASP GLU LEU LEU PHE TYR
SEQRES 17 L 218 LYS ARG LYS MET ASP LYS LYS LYS ARG ASN
SEQRES 1 M 144 MET THR THR LYS VAL LYS ARG VAL GLN THR PHE GLY LYS
SEQRES 2 M 144 LYS LYS THR ALA VAL ALA VAL ALA THR VAL THR ASN GLY
SEQRES 3 M 144 LYS GLY LEU ILE LYS LEU ASN GLY LYS ASN LEU ASP LEU
SEQRES 4 M 144 VAL GLU PRO TYR ILE LEU LYS THR LYS VAL TYR GLU PRO
SEQRES 5 M 144 LEU TRP LEU ILE GLY SER GLY LYS LEU LYS ASN LEU ASP
SEQRES 6 M 144 ILE ARG ILE ARG VAL LYS GLY GLY GLY GLN THR SER GLN
SEQRES 7 M 144 ILE TYR ALA ILE ARG GLN ALA ILE GLY LYS GLY ILE ILE
SEQRES 8 M 144 SER TYR TYR GLN LYS TYR VAL ASP GLU SER THR LYS LYS
SEQRES 9 M 144 GLU LEU LYS ASP VAL LEU LEU ARG TYR ASP ARG SER LEU
SEQRES 10 M 144 LEU VAL GLY ASP THR ARG ARG CYS GLU PRO LYS LYS PHE
SEQRES 11 M 144 GLY GLY LYS GLY ALA ARG ALA ARG TYR GLN LYS SER TYR
SEQRES 12 M 144 ARG
SEQRES 1 N 118 MET SER LYS LEU MET LYS GLY ALA ILE ASP ASN GLU LYS
SEQRES 2 N 118 TYR ARG LEU ARG ARG ILE ARG ILE ALA LEU THR SER LYS
SEQRES 3 N 118 ASN LEU ARG ALA ILE GLU LYS VAL CYS SER ASP ILE MET
SEQRES 4 N 118 LYS GLY ALA LYS GLU LYS ASN LEU ASN VAL SER GLY PRO
SEQRES 5 N 118 VAL ARG LEU PRO VAL LYS THR LEU ARG ILE THR THR ARG
SEQRES 6 N 118 LYS SER PRO CYS GLY GLU GLY THR ASN THR TRP ASP ARG
SEQRES 7 N 118 PHE GLU LEU ARG ILE TYR LYS ARG LEU ILE ASP LEU TYR
SEQRES 8 N 118 SER GLN CYS GLU VAL VAL THR GLN MET THR SER ILE ASN
SEQRES 9 N 118 ILE ASP PRO VAL VAL GLU VAL GLU VAL ILE ILE THR ASP
SEQRES 10 N 118 SER
SEQRES 1 O 137 MET ASP LYS GLN THR LEU PRO HIS HIS LYS TYR SER TYR
SEQRES 2 O 137 ILE PRO LYS GLN ASN LYS LYS LEU ILE TYR GLU TYR LEU
SEQRES 3 O 137 PHE LYS GLU GLY VAL ILE VAL VAL GLU LYS ASP ALA LYS
SEQRES 4 O 137 ILE PRO ARG HIS PRO HIS LEU ASN VAL PRO ASN LEU HIS
SEQRES 5 O 137 ILE MET MET THR LEU LYS SER LEU LYS SER ARG ASN TYR
SEQRES 6 O 137 VAL GLU GLU LYS TYR ASN TRP LYS HIS GLN TYR PHE ILE
SEQRES 7 O 137 LEU ASN ASN GLU GLY ILE GLU TYR LEU ARG GLU PHE LEU
SEQRES 8 O 137 HIS LEU PRO PRO SER ILE PHE PRO ALA THR LEU SER LYS
SEQRES 9 O 137 LYS THR VAL ASN ARG ALA PRO LYS MET ASP GLU ASP ILE
SEQRES 10 O 137 SER ARG ASP VAL ARG GLN PRO MET GLY ARG GLY ARG ALA
SEQRES 11 O 137 PHE ASP ARG ARG PRO PHE GLU
SEQRES 1 P 151 MET ALA SER LYS LYS VAL LYS THR PRO GLN PRO GLU THR
SEQRES 2 P 151 ALA ILE VAL SER GLY PRO GLN PRO LYS GLU GLY GLU LEU
SEQRES 3 P 151 VAL PHE GLY VAL ALA HIS ILE PHE ALA SER PHE ASN ASP
SEQRES 4 P 151 THR PHE ILE HIS VAL THR ASP LEU SER GLY ARG GLU THR
SEQRES 5 P 151 LEU VAL ARG ILE THR GLY GLY MET LYS VAL LYS ALA ASP
SEQRES 6 P 151 ARG ASP GLU SER SER PRO TYR ALA ALA MET MET ALA ALA
SEQRES 7 P 151 GLN ASP VAL ALA ALA ARG LEU LYS GLU LEU GLY VAL THR
SEQRES 8 P 151 ALA ILE HIS ILE LYS LEU ARG ALA SER GLY GLY THR LYS
SEQRES 9 P 151 SER LYS THR PRO GLY PRO GLY ALA GLN SER ALA LEU ARG
SEQRES 10 P 151 ALA LEU ALA ARG SER GLY LEU LYS ILE GLY ARG ILE GLU
SEQRES 11 P 151 ASP VAL THR PRO ILE PRO THR ASP SER THR ARG LYS LYS
SEQRES 12 P 151 SER GLY ARG ARG GLY ARG ARG LEU
SEQRES 1 Q 145 MET GLY SER GLY LYS PRO SER GLY LEU ARG ALA ALA ARG
SEQRES 2 Q 145 LYS LEU ARG ILE ARG ARG ARG THR GLN ARG TRP ALA ASP
SEQRES 3 Q 145 LYS SER TYR LYS LYS SER HIS LEU GLY THR ARG TRP LYS
SEQRES 4 Q 145 SER ASN PRO PHE ARG GLY SER SER HIS ALA LYS GLY ILE
SEQRES 5 Q 145 VAL VAL GLU LYS VAL ALA ILE GLU ALA LYS GLN PRO ASN
SEQRES 6 Q 145 SER ALA TYR ARG LYS CYS VAL ARG VAL GLN LEU ILE LYS
SEQRES 7 Q 145 ASN GLY LYS LYS ILE THR ALA PHE VAL PRO GLY ASP GLY
SEQRES 8 Q 145 CYS LEU ASN PHE ILE ASP GLU ASN ASP GLU VAL LEU VAL
SEQRES 9 Q 145 SER GLY PHE GLY ARG SER GLY HIS SER VAL GLY ASP LEU
SEQRES 10 Q 145 PRO GLY VAL LYS PHE LYS VAL VAL LYS VAL ALA ARG VAL
SEQRES 11 Q 145 SER LEU LEU ALA LEU PHE LYS GLU LYS LYS GLU LYS PRO
SEQRES 12 Q 145 ARG SER
SEQRES 1 R 141 MET SER ASP VAL GLU SER ALA ASP ASN ASN VAL VAL VAL
SEQRES 2 R 141 GLU GLU LYS ALA VAL PHE ASP ASN VAL THR ALA ILE GLN
SEQRES 3 R 141 LYS VAL ILE LYS ASN ALA HIS VAL HIS ASP GLY LEU LYS
SEQRES 4 R 141 ILE GLY ILE ARG GLU VAL ILE LYS SER ILE GLU SER GLN
SEQRES 5 R 141 GLU ALA LYS VAL CYS PHE LEU SER ASP VAL CYS SER GLU
SEQRES 6 R 141 PRO ALA TYR LYS LYS LEU ILE THR THR LEU CYS ALA GLU
SEQRES 7 R 141 LYS ASN ILE PRO LEU PHE MET VAL GLN ASN ASP SER LYS
SEQRES 8 R 141 ASP LEU GLY HIS TRP ALA GLY LEU PHE LYS LEU ASP ASN
SEQRES 9 R 141 GLU GLY ASN ALA ARG LYS ILE ILE GLY ALA SER SER VAL
SEQRES 10 R 141 ALA VAL VAL ASP PHE GLY GLU ASP SER ALA GLU LYS ASP
SEQRES 11 R 141 PHE LEU LEU SER GLN ASN GLN THR VAL THR ALA
SEQRES 1 S 156 MET SER LEU GLN VAL ILE ASP ASN ASN ASP PHE GLN HIS
SEQRES 2 S 156 ILE LEU ARG ILE LEU ASN THR ASN VAL ASP GLY LYS GLU
SEQRES 3 S 156 LYS VAL ILE ILE ALA LEU THR ALA ILE LYS GLY ILE GLY
SEQRES 4 S 156 LYS ARG MET ALA THR VAL ILE CYS LYS GLN ALA ASN VAL
SEQRES 5 S 156 ASP PRO THR LYS ARG ALA GLY GLU LEU THR THR GLU GLU
SEQRES 6 S 156 ILE ASP ASN ILE VAL HIS ILE MET SER THR PRO THR GLN
SEQRES 7 S 156 PHE LYS ILE PRO ASP TRP PHE LEU ASN ARG ARG LYS ASP
SEQRES 8 S 156 LEU LYS GLU GLY LYS ASN ILE HIS VAL ILE ALA ASN GLN
SEQRES 9 S 156 LEU ASP SER TYR LEU ARG GLU ASP LEU GLU ARG MET LYS
SEQRES 10 S 156 LYS ILE ARG LEU HIS ARG GLY LEU ARG HIS HIS TRP GLY
SEQRES 11 S 156 LEU ARG VAL ARG GLY GLN HIS THR LYS THR THR GLY ARG
SEQRES 12 S 156 ARG GLY ARG THR VAL GLY VAL ALA LYS LYS LYS GLY ALA
SEQRES 1 T 54 MET GLY CYS ILE LEU ASN VAL HIS PRO LYS LYS TYR GLY
SEQRES 2 T 54 GLN GLY SER ARG GLN CYS ARG VAL CYS SER ASN LYS HIS
SEQRES 3 T 54 ALA ILE ILE ARG LYS TYR ASN ILE ASN ILE CYS ARG GLN
SEQRES 4 T 54 CYS PHE ARG GLU ARG ALA ASP ILE ILE GLY PHE LYS LYS
SEQRES 5 T 54 TYR ARG
SEQRES 1 U 151 MET GLY ARG MET TYR GLY LYS GLY LYS GLY ILE SER SER
SEQRES 2 U 151 SER THR LEU PRO TYR LYS ARG LYS GLN PRO SER TRP LEU
SEQRES 3 U 151 LYS GLN LYS PRO SER GLU ILE GLU ASP ALA ILE ILE LYS
SEQRES 4 U 151 LEU ALA LYS LYS GLY GLN THR PRO SER GLN ILE GLY ALA
SEQRES 5 U 151 THR LEU ARG ASP ASN TYR GLY ILE PRO GLN VAL LYS SER
SEQRES 6 U 151 VAL THR GLY ASN LYS ILE LEU ARG ILE LEU ARG ALA GLN
SEQRES 7 U 151 GLY ILE ALA THR THR ILE PRO GLU ASP LEU TYR PHE LEU
SEQRES 8 U 151 ILE LYS LYS ALA VAL SER MET ARG LYS HIS LEU GLU LYS
SEQRES 9 U 151 ASN LYS LYS ASP LYS ASP CYS LYS PHE ARG LEU ILE LEU
SEQRES 10 U 151 THR GLU SER LYS ILE HIS ARG ILE SER ARG TYR TYR LYS
SEQRES 11 U 151 ARG LYS LYS LEU LEU PRO SER ASN TRP LYS TYR GLN SER
SEQRES 12 U 151 SER THR ALA SER ALA LEU ILE ALA
SEQRES 1 V 161 MET ALA THR THR LEU ASP VAL GLN HIS GLU ARG ALA TYR
SEQRES 2 V 161 GLN LYS GLN GLU GLY ALA SER PHE PHE ASN SER LYS LYS
SEQRES 3 V 161 ILE LYS LYS GLY SER LYS SER TYR ILE ARG TYR TRP LYS
SEQRES 4 V 161 LYS VAL GLY LEU GLY PHE ALA THR PRO LYS GLU ALA LYS
SEQRES 5 V 161 GLU GLY VAL TYR VAL ASP LYS LYS CYS PRO PHE THR GLY
SEQRES 6 V 161 ASN VAL SER ILE ARG GLY ARG ILE LEU LYS GLY MET VAL
SEQRES 7 V 161 ILE SER ASN LYS MET LYS ARG THR ILE ILE ILE ARG ARG
SEQRES 8 V 161 ASN TYR LEU HIS TYR VAL LYS LYS TYR ASN ARG PHE GLU
SEQRES 9 V 161 LYS ARG HIS LYS ASN ILE PRO CYS HIS CYS SER PRO CYS
SEQRES 10 V 161 PHE ASP VAL LYS GLU GLY ASP ILE VAL THR VAL GLY GLN
SEQRES 11 V 161 CYS ARG PRO LEU SER LYS THR VAL ARG PHE ASN VAL LEU
SEQRES 12 V 161 HIS VAL GLU LYS HIS GLN ILE PHE GLY SER ALA ARG LYS
SEQRES 13 V 161 GLN PHE VAL LEU PHE
SEQRES 1 W 137 MET GLY ARG VAL ARG THR LYS THR ILE LYS ARG ALA ALA
SEQRES 2 W 137 ARG GLN ILE VAL GLU LYS TYR TYR ALA LYS LEU THR LEU
SEQRES 3 W 137 ASP PHE GLN ILE ASN LYS LYS ILE THR GLU GLU VAL ALA
SEQRES 4 W 137 ILE ILE PRO SER LYS ARG MET LYS ASN LYS VAL ALA GLY
SEQRES 5 W 137 PHE VAL THR HIS LEU MET LYS ARG ILE GLN LYS GLY PRO
SEQRES 6 W 137 VAL ARG GLY ILE SER LEU LYS LEU GLN GLU GLU GLU ARG
SEQRES 7 W 137 GLU ARG ARG LEU ASP PHE VAL PRO GLU LYS SER GLN ILE
SEQRES 8 W 137 ASP VAL SER VAL ILE TYR VAL GLU PRO ASP THR LEU ARG
SEQRES 9 W 137 MET ILE LYS SER LEU GLY ILE ASN ILE SER ASN MET LYS
SEQRES 10 W 137 VAL HIS ASN PRO MET ILE ASN THR ASN GLN GLN LYS GLN
SEQRES 11 W 137 ASN ARG MET ASN ASN GLN PHE
SEQRES 1 X 145 MET GLU ASP ALA ASN LYS PRO LYS LYS ARG THR PHE ARG
SEQRES 2 X 145 THR PHE GLN TYR ARG GLY VAL ASP LEU ASP LYS LEU LEU
SEQRES 3 X 145 ASP LEU SER GLN ASP GLU LEU ILE LYS LEU PHE LYS ALA
SEQRES 4 X 145 ARG GLN ARG ARG LYS PHE GLN ARG GLY ILE SER LYS LYS
SEQRES 5 X 145 ALA LYS SER LEU LEU LYS LYS ILE ARG LYS SER LYS LYS
SEQRES 6 X 145 ASN CYS GLU PRO GLY GLU LYS PRO ASN PRO VAL PRO THR
SEQRES 7 X 145 HIS LEU ARG ASN MET THR ILE ILE PRO GLU MET VAL GLY
SEQRES 8 X 145 SER ILE VAL ALA VAL HIS ASN GLY LYS GLN TYR THR ASN
SEQRES 9 X 145 VAL GLU ILE LYS PRO GLU MET ILE GLY TYR TYR LEU GLY
SEQRES 10 X 145 GLU PHE SER ILE THR TYR LYS HIS THR ARG HIS GLY LYS
SEQRES 11 X 145 PRO GLY ILE GLY ALA THR HIS SER SER ARG PHE ILE PRO
SEQRES 12 X 145 LEU LYS
SEQRES 1 Y 170 MET ALA GLU GLN PHE THR GLU ASP ILE GLY VAL VAL ASN
SEQRES 2 Y 170 LYS ARG LEU LEU GLU PRO VAL PRO PHE VAL LYS THR ASN
SEQRES 3 Y 170 ASN CYS ILE LYS ASP VAL ASP ALA ASP LEU PHE ILE ARG
SEQRES 4 Y 170 SER TYR ALA THR HIS LEU LYS LEU HIS ASN LYS ILE THR
SEQRES 5 Y 170 TYR PRO LYS TRP CYS THR PHE VAL LYS THR GLY LYS GLY
SEQRES 6 Y 170 ARG LYS LEU ALA PRO LEU ASN GLU ASP TRP TYR PHE ILE
SEQRES 7 Y 170 ARG ALA SER SER ILE LEU ARG ARG LEU TYR LEU HIS PRO
SEQRES 8 Y 170 ASP ILE GLY VAL GLY PHE LEU ARG ARG GLN PHE SER SER
SEQRES 9 Y 170 LYS GLN ARG ARG GLY VAL ALA PRO ASN HIS THR SER LEU
SEQRES 10 Y 170 ALA SER GLY LYS ILE LEU ARG SER ILE LEU GLN GLN LEU
SEQRES 11 Y 170 GLU ASN LEU GLY TYR VAL GLU GLN ASN PRO LYS LYS LYS
SEQRES 12 Y 170 GLY ARG ARG LEU THR THR LYS GLY GLU ASN ALA ILE ASN
SEQRES 13 Y 170 ASN PHE ALA ARG TYR ILE ASN LYS LYS VAL TYR ASN LYS
SEQRES 14 Y 170 GLU
SEQRES 1 Z 82 MET PHE ASN ASP GLN LYS VAL LEU VAL ASP ILE TYR ILE
SEQRES 2 Z 82 PRO ARG LYS CYS SER ALA THR SER ARG LEU ILE PRO ALA
SEQRES 3 Z 82 LYS GLU HIS GLY ALA VAL GLN ILE ASN VAL GLY MET VAL
SEQRES 4 Z 82 ASP ALA ASN GLY VAL TYR ASN GLY LYS THR GLU THR PHE
SEQRES 5 Z 82 ALA ILE SER GLY HIS VAL ARG GLN ASN GLY GLU SER ASP
SEQRES 6 Z 82 ALA CYS LEU ASN ARG LEU MET TYR GLU LYS LYS LEU LEU
SEQRES 7 Z 82 SER PHE GLN ASN
SEQRES 1 1 133 MET THR ASP GLN PHE THR ILE ARG VAL LYS LYS TYR MET
SEQRES 2 1 133 SER ASN PRO LEU LEU ARG ARG LYS GLN PHE ALA LEU GLU
SEQRES 3 1 133 ILE LEU HIS PRO ASN LYS GLY SER VAL ALA LYS LYS GLU
SEQRES 4 1 133 VAL LYS GLU ARG LEU ALA LYS MET TYR LYS LEU ASN ASN
SEQRES 5 1 133 VAL ASN THR ILE VAL LEU PHE GLY PHE LYS THR LEU PHE
SEQRES 6 1 133 GLY GLY GLY ARG THR LYS GLY PHE GLY LEU ILE TYR LYS
SEQRES 7 1 133 ASN VAL ASP ALA VAL LYS LYS PHE GLU LYS LYS TYR ARG
SEQRES 8 1 133 LEU VAL ARG GLU GLY LEU ILE ASP LYS GLU THR LYS ALA
SEQRES 9 1 133 GLY ARG ARG ALA SER LYS GLU LEU LYS ASN ARG ARG LYS
SEQRES 10 1 133 LYS VAL ARG GLY THR GLU LYS THR LYS VAL SER GLY ALA
SEQRES 11 1 133 LYS LYS LYS
SEQRES 1 2 105 MET PRO PRO LYS GLU ARG LYS THR LYS GLU GLN ILE ALA
SEQRES 2 2 105 ALA ALA ALA ALA ALA SER GLY ARG THR LYS LYS LYS LYS
SEQRES 3 2 105 TRP GLY LYS GLY LYS ASN LYS GLU LYS LEU ASN HIS ALA
SEQRES 4 2 105 VAL PHE ILE ASP LYS SER LEU HIS SER LYS ILE LEU GLU
SEQRES 5 2 105 CYS LYS ASN MET LYS VAL ILE THR PRO SER ALA ILE ALA
SEQRES 6 2 105 GLU LYS TYR LYS VAL ASN LEU SER VAL ALA ARG ALA VAL
SEQRES 7 2 105 ILE ASN HIS LEU ALA ASP LYS LYS LEU ILE ALA GLU VAL
SEQRES 8 2 105 CYS VAL GLN SER HIS SER GLN LYS LEU TYR THR LYS VAL
SEQRES 9 2 105 ALA
SEQRES 1 3 107 MET PRO LYS LYS ARG ARG ASN GLY GLY ARG SER LYS HIS
SEQRES 2 3 107 ASN ARG GLY HIS VAL ASN PRO LEU ARG CYS SER ASN CYS
SEQRES 3 3 107 GLY ARG CYS VAL PRO LYS ASP LYS ALA ILE LYS ARG PHE
SEQRES 4 3 107 ASN ILE ARG ASN ILE VAL ASP THR SER ALA GLN ARG ASP
SEQRES 5 3 107 ILE LYS GLU ALA SER VAL TYR SER THR PHE GLN LEU PRO
SEQRES 6 3 107 LYS LEU TYR ILE LYS GLN CYS TYR CYS VAL SER CYS ALA
SEQRES 7 3 107 ILE HIS SER ARG PHE VAL ARG VAL ARG SER ARG GLU GLN
SEQRES 8 3 107 ARG ARG VAL ARG LYS GLU THR ALA LYS HIS VAL ASN PRO
SEQRES 9 3 107 SER GLN LEU
SEQRES 1 4 82 MET ASN VAL ASP LEU LEU ASN PRO ASP PRO VAL GLU GLU
SEQRES 2 4 82 SER LYS LYS HIS LYS LEU LYS ARG LEU ILE PRO THR PRO
SEQRES 3 4 82 ASN SER TYR PHE MET ASP VAL LYS CYS PRO GLY CYS LEU
SEQRES 4 4 82 GLN ILE THR THR LEU PHE SER HIS ALA GLN ASN VAL VAL
SEQRES 5 4 82 LEU CYS GLY SER CYS ASN ILE MET LEU CYS GLN PRO THR
SEQRES 6 4 82 GLY GLY LYS CYS LYS LEU THR GLU GLY CYS SER PHE ARG
SEQRES 7 4 82 LYS LYS ILE GLU
SEQRES 1 5 67 MET GLU LYS SER LYS LEU ALA LYS VAL GLU LYS VAL LEU
SEQRES 2 5 67 GLY ARG THR GLY SER ARG GLY GLY VAL ILE GLN VAL ARG
SEQRES 3 5 67 ALA GLN PHE MET GLY ASP SER GLU LEU ALA GLY ARG PHE
SEQRES 4 5 67 LEU ILE ARG ASN VAL LYS GLY PRO VAL ARG GLU GLY ASP
SEQRES 5 5 67 ILE LEU ALA LEU LEU GLU THR GLU ARG GLU ALA ARG ARG
SEQRES 6 5 67 LEU ARG
SEQRES 1 6 58 MET GLY LYS VAL HIS GLY SER LEU ALA ARG ALA GLY LYS
SEQRES 2 6 58 VAL LYS ASN GLN THR PRO LYS VAL PRO LYS LEU ASP LYS
SEQRES 3 6 58 LYS LYS ARG LEU THR GLY ARG ALA LYS LYS ARG GLN LEU
SEQRES 4 6 58 TYR ASN ARG ARG PHE SER ASP ASN GLY GLY ARG LYS LYS
SEQRES 5 6 58 GLY PRO ASN SER LYS ALA
SEQRES 1 7 74 G G G U A A U U G G C G C
SEQRES 2 7 74 A G U U G G U U A G C G C
SEQRES 3 7 74 G C G G G U C U C A U A A
SEQRES 4 7 74 U C C C G A G G U C G U G
SEQRES 5 7 74 A G U U C G A U C C U C A
SEQRES 6 7 74 C A U U A C C C A
HET MG A2101 1
HET MG A2102 1
HET MG A2103 1
HET MG A2104 1
HET MG A2105 1
HET MG A2106 1
HET MG A2107 1
HET MG A2108 1
HET MG A2109 1
HET MG A2110 1
HET MG A2111 1
HET MG A2112 1
HET MG A2113 1
HET MG A2114 1
HET MG A2115 1
HET MG A2116 1
HET MG A2117 1
HET MG A2118 1
HET MG A2119 1
HET MG A2120 1
HET MG A2121 1
HET MG A2122 1
HET MG A2123 1
HET MG A2124 1
HET MG A2125 1
HET MG A2126 1
HET MG A2127 1
HET MG A2128 1
HET MG A2129 1
HET MG A2130 1
HET MG A2131 1
HET MG A2132 1
HET MG A2133 1
HET MG A2134 1
HET MG A2135 1
HET MG A2136 1
HET MG A2137 1
HET MG A2138 1
HET MG A2139 1
HET MG A2140 1
HET MG A2141 1
HET MG A2142 1
HET MG A2143 1
HET MG A2144 1
HET MG A2145 1
HET MG A2146 1
HET MG A2147 1
HET MG A2148 1
HET MG A2149 1
HET MG A2150 1
HET MG A2151 1
HET MG A2152 1
HET MG A2153 1
HET MG A2154 1
HET MG A2155 1
HET MG A2156 1
HET MG A2157 1
HET MG A2158 1
HET MG A2159 1
HET MG A2160 1
HET 34G A2168 35
HET MG A2161 1
HET MG A2162 1
HET MG A2163 1
HET MG A2164 1
HET MG A2165 1
HET MG A2166 1
HET MG A2167 1
HET ZN T 100 1
HETNAM MG MAGNESIUM ION
HETNAM 34G EMETINE
HETNAM ZN ZINC ION
HETSYN 34G (3BETA,14BETA)-6',7',10,11-TETRAMETHOXYEMETAN
FORMUL 34 MG 67(MG 2+)
FORMUL 94 34G C29 H40 N2 O4
FORMUL 02 ZN ZN 2+
HELIX 1 1 ALA B 57 LYS B 62 1 6
HELIX 2 2 LEU B 70 ASN B 75 1 6
HELIX 3 3 ASP B 76 ALA B 80 5 5
HELIX 4 4 THR B 106 ILE B 114 1 9
HELIX 5 5 ARG B 146 THR B 150 5 5
HELIX 6 6 GLN B 157 VAL B 179 1 23
HELIX 7 7 LEU B 180 ILE B 189 1 10
HELIX 8 8 GLU B 191 LYS B 202 1 12
HELIX 9 9 ASP B 224 THR B 233 1 10
HELIX 10 10 GLU C 11 CYS C 20 1 10
HELIX 11 11 GLU C 30 ARG C 35 5 6
HELIX 12 12 LEU C 50 ILE C 67 1 18
HELIX 13 13 ASN C 69 ALA C 71 5 3
HELIX 14 14 GLY C 82 THR C 93 1 12
HELIX 15 15 ASP C 129 ALA C 139 1 11
HELIX 16 16 GLY C 166 LYS C 185 1 20
HELIX 17 17 SER D 6 LEU D 29 1 24
HELIX 18 18 ILE D 66 PHE D 78 1 13
HELIX 19 19 CYS D 98 GLY D 113 1 16
HELIX 20 20 VAL D 116 SER D 130 1 15
HELIX 21 21 GLY D 162 PHE D 168 1 7
HELIX 22 22 GLU E 20 GLY E 35 1 16
HELIX 23 23 LYS E 39 LEU E 62 1 24
HELIX 24 24 SER E 66 GLY E 84 1 19
HELIX 25 25 THR E 100 ARG E 107 1 8
HELIX 26 26 ARG E 108 LEU E 116 1 9
HELIX 27 27 SER E 121 GLN E 131 1 11
HELIX 28 28 ARG E 149 GLU E 153 5 5
HELIX 29 29 SER E 162 GLY E 166 5 5
HELIX 30 30 VAL E 172 ALA E 186 1 15
HELIX 31 31 PRO F 15 MET F 19 5 5
HELIX 32 32 LYS F 37 SER F 41 5 5
HELIX 33 33 PRO F 43 ASN F 50 1 8
HELIX 34 34 THR F 57 GLN F 67 1 11
HELIX 35 35 THR F 115 LYS F 120 1 6
HELIX 36 36 ASP F 247 LYS F 257 1 11
HELIX 37 37 THR G 45 GLU G 53 1 9
HELIX 38 38 SER G 58 HIS G 65 1 8
HELIX 39 39 GLU G 71 PHE G 79 1 9
HELIX 40 40 GLU G 132 LEU G 148 1 17
HELIX 41 41 ALA G 193 GLY G 204 1 12
HELIX 42 42 THR G 218 THR G 233 1 16
HELIX 43 43 THR G 238 LYS G 243 5 6
HELIX 44 44 SER G 250 TRP G 255 1 6
HELIX 45 45 TRP G 255 GLU G 260 1 6
HELIX 46 46 ASP H 20 LEU H 25 1 6
HELIX 47 47 ASP H 39 ILE H 41 5 3
HELIX 48 48 ARG H 137 ASN H 146 1 10
HELIX 49 49 THR H 180 ASN H 213 1 34
HELIX 50 50 LEU I 24 ILE I 30 1 7
HELIX 51 51 PHE I 52 LEU I 56 5 5
HELIX 52 52 PRO I 58 MET I 68 1 11
HELIX 53 53 HIS I 70 ASN I 74 5 5
HELIX 54 54 LYS I 76 MET I 94 1 19
HELIX 55 55 ASN I 98 GLY I 111 1 14
HELIX 56 56 SER I 133 PHE I 154 1 22
HELIX 57 57 SER I 159 GLU I 174 1 16
HELIX 58 58 SER I 178 ARG I 195 1 18
HELIX 59 59 LEU J 16 SER J 31 1 16
HELIX 60 60 TYR J 66 TYR J 72 1 7
HELIX 61 61 ILE J 76 THR J 88 1 13
HELIX 62 62 THR J 118 VAL J 131 1 14
HELIX 63 63 ASN J 164 ARG J 181 1 18
HELIX 64 64 SER K 5 GLY K 21 1 17
HELIX 65 65 SER K 31 LYS K 44 1 14
HELIX 66 66 GLU K 85 LEU K 94 1 10
HELIX 67 67 HIS K 113 HIS K 120 1 8
HELIX 68 68 ASN L 87 LYS L 94 1 8
HELIX 69 69 SER L 106 PHE L 117 1 12
HELIX 70 70 ASP L 169 GLN L 178 1 10
HELIX 71 71 ARG L 188 GLY L 193 1 6
HELIX 72 72 GLY L 202 ASP L 213 1 12
HELIX 73 73 LEU M 45 GLY M 57 1 13
HELIX 74 74 GLN M 75 VAL M 98 1 24
HELIX 75 75 ASP M 99 ASP M 114 1 16
HELIX 76 76 ASN N 27 GLU N 44 1 18
HELIX 77 77 GLN N 93 SER N 102 1 10
HELIX 78 78 PRO O 15 GLY O 30 1 16
HELIX 79 79 PRO O 49 ASN O 64 1 16
HELIX 80 80 ASN O 80 GLU O 89 1 10
HELIX 81 81 SER P 70 GLY P 89 1 20
HELIX 82 82 PRO P 110 GLY P 123 1 14
HELIX 83 83 ALA Q 11 TRP Q 24 1 14
HELIX 84 84 ASP Q 26 LEU Q 34 1 9
HELIX 85 85 GLY Q 35 SER Q 40 1 6
HELIX 86 86 SER Q 131 GLU Q 138 1 8
HELIX 87 87 THR R 23 ASP R 36 1 14
HELIX 88 88 ILE R 42 GLU R 50 1 9
HELIX 89 89 PRO R 66 GLU R 78 1 13
HELIX 90 90 SER R 90 ALA R 97 1 8
HELIX 91 91 GLU R 128 GLN R 135 1 8
HELIX 92 92 LYS S 27 ALA S 34 1 8
HELIX 93 93 LYS S 40 ASN S 51 1 12
HELIX 94 94 ARG S 57 LEU S 61 5 5
HELIX 95 95 THR S 62 SER S 74 1 13
HELIX 96 96 ILE S 101 ARG S 120 1 20
HELIX 97 97 LEU S 121 GLY S 130 1 10
HELIX 98 98 ARG T 30 ILE T 34 5 5
HELIX 99 99 ARG T 38 GLY T 49 1 12
HELIX 100 100 LYS U 29 LYS U 43 1 15
HELIX 101 101 THR U 46 ASN U 57 1 12
HELIX 102 102 GLN U 62 THR U 67 1 6
HELIX 103 103 LYS U 70 GLY U 79 1 10
HELIX 104 104 PRO U 85 ASN U 105 1 21
HELIX 105 105 ASP U 108 LYS U 132 1 25
HELIX 106 106 THR U 145 ILE U 150 1 6
HELIX 107 107 PRO V 48 GLU V 53 1 6
HELIX 108 108 SER V 153 GLN V 157 5 5
HELIX 109 109 THR W 6 LYS W 19 1 14
HELIX 110 110 ASP W 27 ALA W 39 1 13
HELIX 111 111 LYS W 44 ILE W 61 1 18
HELIX 112 112 LEU W 71 ASP W 83 1 13
HELIX 113 113 GLU W 99 GLY W 110 1 12
HELIX 114 114 LEU X 22 LEU X 28 1 7
HELIX 115 115 SER X 29 PHE X 37 1 9
HELIX 116 116 LYS X 38 GLY X 48 1 11
HELIX 117 117 ILE X 49 CYS X 67 1 19
HELIX 118 118 ILE X 86 VAL X 90 5 5
HELIX 119 119 CYS Y 28 VAL Y 32 5 5
HELIX 120 120 ASP Y 33 ASN Y 49 1 17
HELIX 121 121 LYS Y 55 VAL Y 60 5 6
HELIX 122 122 GLY Y 63 LYS Y 67 5 5
HELIX 123 123 ASP Y 74 HIS Y 90 1 17
HELIX 124 124 GLY Y 94 PHE Y 102 1 9
HELIX 125 125 SER Y 119 GLY Y 134 1 16
HELIX 126 126 THR Y 148 ASN Y 168 1 21
HELIX 127 127 PRO Z 25 HIS Z 29 5 5
HELIX 128 128 SER Z 55 GLY Z 62 1 8
HELIX 129 129 GLU Z 63 LYS Z 75 1 13
HELIX 130 130 ALA 1 36 TYR 1 48 1 13
HELIX 131 131 ASN 1 52 ASN 1 54 5 3
HELIX 132 132 ASN 1 79 PHE 1 86 1 8
HELIX 133 133 LYS 1 88 GLY 1 96 1 9
HELIX 134 134 ARG 1 107 ASN 1 114 1 8
HELIX 135 135 THR 2 60 LYS 2 69 1 10
HELIX 136 136 ASN 2 71 ASP 2 84 1 14
HELIX 137 137 THR 3 47 SER 3 57 1 11
HELIX 138 138 CYS 3 74 SER 3 81 1 8
HELIX 139 139 SER 3 88 VAL 3 94 1 7
HELIX 140 140 GLY 6 12 THR 6 18 1 7
HELIX 141 141 GLY 6 32 PHE 6 44 1 13
SHEET 1 A 4 ASN B 42 VAL B 48 0
SHEET 2 A 4 GLU B 28 LYS B 33 -1 N LEU B 32 O GLY B 44
SHEET 3 A 4 ASP B 95 CYS B 96 1 O CYS B 96 N LYS B 33
SHEET 4 A 4 ILE B 91 ILE B 92 -1 N ILE B 92 O ASP B 95
SHEET 1 B 3 ILE B 65 GLU B 67 0
SHEET 2 B 3 LYS B 85 SER B 87 -1 O LEU B 86 N TYR B 66
SHEET 3 B 3 ASP B 99 GLY B 102 -1 O CYS B 101 N LYS B 85
SHEET 1 C 3 ASP B 126 LYS B 128 0
SHEET 2 C 3 HIS B 134 ARG B 136 -1 O LEU B 135 N VAL B 127
SHEET 3 C 3 LYS B 216 LYS B 219 -1 O LEU B 218 N HIS B 134
SHEET 1 D 3 ILE C 24 GLY C 25 0
SHEET 2 D 3 HIS C 46 ILE C 48 -1 O HIS C 46 N GLY C 25
SHEET 3 D 3 VAL C 37 ARG C 40 -1 N TYR C 38 O ILE C 47
SHEET 1 E 4 VAL C 73 VAL C 76 0
SHEET 2 E 4 LEU C 120 VAL C 123 1 O ILE C 122 N VAL C 76
SHEET 3 E 4 ILE C 144 ALA C 145 1 O ILE C 144 N LEU C 121
SHEET 4 E 4 ILE C 158 ALA C 159 1 O ILE C 158 N ALA C 145
SHEET 1 F 4 MET D 151 ARG D 154 0
SHEET 2 F 4 GLY D 134 GLY D 141 -1 N VAL D 139 O MET D 151
SHEET 3 F 4 GLY D 181 MET D 190 -1 O GLY D 184 N SER D 140
SHEET 4 F 4 VAL D 169 LEU D 178 -1 N ASN D 170 O ILE D 189
SHEET 1 G 3 GLN E 139 MET E 140 0
SHEET 2 G 3 ARG E 135 VAL E 136 -1 N VAL E 136 O GLN E 139
SHEET 3 G 3 ILE E 156 ASP E 157 -1 O ASP E 157 N ARG E 135
SHEET 1 H 2 LEU F 9 LYS F 10 0
SHEET 2 H 2 TYR F 27 ALA F 28 -1 O ALA F 28 N LEU F 9
SHEET 1 I 5 LYS F 75 VAL F 76 0
SHEET 2 I 5 VAL F 70 VAL F 72 -1 N VAL F 72 O LYS F 75
SHEET 3 I 5 VAL F 89 ILE F 92 -1 O HIS F 91 N LYS F 71
SHEET 4 I 5 GLU F 97 TYR F 103 -1 O PHE F 99 N ILE F 90
SHEET 5 I 5 PHE F 109 PRO F 111 -1 O VAL F 110 N LEU F 102
SHEET 1 J 5 SER F 146 PRO F 148 0
SHEET 2 J 5 LEU F 136 THR F 141 -1 N ALA F 139 O ILE F 147
SHEET 3 J 5 TYR F 121 ARG F 132 -1 N LEU F 130 O ILE F 138
SHEET 4 J 5 THR F 159 ASP F 163 -1 O LEU F 162 N LYS F 122
SHEET 5 J 5 VAL F 169 LEU F 173 -1 O LEU F 170 N ARG F 161
SHEET 1 K 3 VAL F 192 GLY F 193 0
SHEET 2 K 3 VAL F 181 VAL F 183 -1 N VAL F 181 O GLY F 193
SHEET 3 K 3 VAL F 225 VAL F 227 -1 O PHE F 226 N MET F 182
SHEET 1 L 3 SER F 197 ILE F 198 0
SHEET 2 L 3 ILE F 207 LYS F 211 -1 O HIS F 209 N SER F 197
SHEET 3 L 3 VAL F 217 ARG F 221 -1 O PHE F 218 N VAL F 210
SHEET 1 M 4 LYS G 89 GLN G 99 0
SHEET 2 M 4 THR G 108 GLY G 117 -1 O ARG G 109 N VAL G 98
SHEET 3 M 4 HIS G 122 ALA G 130 -1 O ALA G 130 N PHE G 110
SHEET 4 M 4 ILE G 149 PRO G 150 -1 O ILE G 149 N CYS G 123
SHEET 1 N 4 VAL G 170 CYS G 174 0
SHEET 2 N 4 VAL G 177 PRO G 183 -1 O LEU G 181 N VAL G 170
SHEET 3 N 4 CYS G 208 PHE G 209 -1 O PHE G 209 N VAL G 182
SHEET 4 N 4 ILE G 190 VAL G 191 1 N VAL G 191 O CYS G 208
SHEET 1 O 5 VAL H 12 GLU H 17 0
SHEET 2 O 5 LYS H 2 ASN H 7 -1 N ASN H 7 O VAL H 12
SHEET 3 O 5 LEU H 111 LYS H 115 1 O LEU H 111 N ASN H 4
SHEET 4 O 5 VAL H 49 ILE H 52 -1 N VAL H 49 O VAL H 114
SHEET 5 O 5 ALA H 35 PRO H 37 -1 N VAL H 36 O PHE H 50
SHEET 1 P 3 MET H 63 ILE H 64 0
SHEET 2 P 3 ARG H 94 GLY H 99 1 O ARG H 98 N ILE H 64
SHEET 3 P 3 ARG H 72 LEU H 76 -1 N VAL H 73 O VAL H 97
SHEET 1 Q 2 GLU I 114 SER I 116 0
SHEET 2 Q 2 ALA I 129 ASP I 131 -1 O VAL I 130 N ASP I 115
SHEET 1 R 3 SER J 46 GLU J 51 0
SHEET 2 R 3 LYS J 58 PRO J 65 -1 O THR J 59 N ILE J 50
SHEET 3 R 3 TYR J 91 LYS J 97 1 O LYS J 97 N ILE J 64
SHEET 1 S 2 ILE J 136 GLY J 138 0
SHEET 2 S 2 MET J 154 LEU J 155 -1 O MET J 154 N ILE J 137
SHEET 1 T 6 ALA J 184 VAL J 185 0
SHEET 2 T 6 ARG J 149 LYS J 152 1 N PHE J 151 O VAL J 185
SHEET 3 T 6 ARG J 140 MET J 143 -1 N SER J 142 O VAL J 150
SHEET 4 T 6 ILE K 47 VAL K 53 -1 O ILE K 52 N ILE J 141
SHEET 5 T 6 ILE K 61 LEU K 65 -1 O ASN K 64 N SER K 49
SHEET 6 T 6 GLN K 24 ILE K 27 -1 N ILE K 27 O ILE K 61
SHEET 1 U 4 CYS K 72 VAL K 74 0
SHEET 2 U 4 LYS K 124 PHE K 129 -1 O PHE K 128 N ALA K 73
SHEET 3 U 4 HIS K 101 THR K 106 -1 N THR K 105 O LYS K 124
SHEET 4 U 4 GLY K 109 ASP K 112 -1 O MET K 111 N LEU K 104
SHEET 1 V 3 LYS L 37 LEU L 38 0
SHEET 2 V 3 ASN L 52 LEU L 60 1 O ILE L 58 N LYS L 37
SHEET 3 V 3 GLN L 42 GLY L 48 -1 N GLN L 42 O ILE L 58
SHEET 1 W 6 ILE L 72 ASN L 75 0
SHEET 2 W 6 SER L 64 TRP L 67 -1 N PHE L 65 O LYS L 74
SHEET 3 W 6 GLY L 197 ILE L 199 1 O GLY L 197 N SER L 64
SHEET 4 W 6 ARG L 180 ILE L 185 -1 N CYS L 184 O TYR L 198
SHEET 5 W 6 ILE L 101 ASP L 105 -1 N ILE L 104 O VAL L 181
SHEET 6 W 6 ILE L 78 TYR L 83 -1 N ASP L 80 O VAL L 103
SHEET 1 X 5 ARG M 7 PHE M 11 0
SHEET 2 X 5 VAL M 18 ASN M 25 -1 O VAL M 23 N VAL M 8
SHEET 3 X 5 LEU M 64 LYS M 71 -1 O ARG M 69 N VAL M 20
SHEET 4 X 5 LYS M 31 LEU M 32 1 N LYS M 31 O ILE M 66
SHEET 5 X 5 LYS M 35 ASN M 36 -1 O LYS M 35 N LEU M 32
SHEET 1 Y 4 VAL N 53 ARG N 54 0
SHEET 2 Y 4 TYR N 84 LEU N 87 -1 O LEU N 87 N VAL N 53
SHEET 3 Y 4 ALA N 22 SER N 25 -1 N SER N 25 O TYR N 84
SHEET 4 Y 4 VAL N 109 GLU N 112 -1 O GLU N 112 N ALA N 22
SHEET 1 Z 3 THR N 59 ARG N 65 0
SHEET 2 Z 3 TRP N 76 ARG N 82 -1 O PHE N 79 N ILE N 62
SHEET 3 Z 3 LYS T 51 LYS T 52 -1 O LYS T 51 N GLU N 80
SHEET 1 AA 3 VAL O 31 ILE O 32 0
SHEET 2 AA 3 PHE O 77 LEU O 79 -1 O PHE O 77 N ILE O 32
SHEET 3 AA 3 VAL O 66 GLU O 68 -1 N GLU O 67 O ILE O 78
SHEET 1 AB 5 THR P 52 ARG P 55 0
SHEET 2 AB 5 HIS P 43 THR P 45 -1 N VAL P 44 O LEU P 53
SHEET 3 AB 5 PHE P 28 PHE P 34 -1 N VAL P 30 O THR P 45
SHEET 4 AB 5 ALA P 92 ARG P 98 1 O LYS P 96 N ILE P 33
SHEET 5 AB 5 LYS P 125 ILE P 126 1 O LYS P 125 N ILE P 93
SHEET 1 AC 6 HIS Q 48 GLU Q 60 0
SHEET 2 AC 6 TYR Q 68 LEU Q 76 -1 O ARG Q 73 N GLU Q 55
SHEET 3 AC 6 LYS Q 82 PHE Q 86 -1 O ILE Q 83 N VAL Q 74
SHEET 4 AC 6 PHE Q 122 VAL Q 127 1 O PHE Q 122 N PHE Q 86
SHEET 5 AC 6 GLU Q 101 GLY Q 106 -1 N SER Q 105 O LYS Q 123
SHEET 6 AC 6 HIS Q 48 GLU Q 60 -1 N ALA Q 49 O VAL Q 104
SHEET 1 AD 3 LEU R 38 ILE R 40 0
SHEET 2 AD 3 VAL R 117 VAL R 119 -1 O ALA R 118 N LYS R 39
SHEET 3 AD 3 VAL R 56 PHE R 58 -1 N PHE R 58 O VAL R 117
SHEET 1 AE 2 ILE T 28 ILE T 29 0
SHEET 2 AE 2 ILE T 36 CYS T 37 -1 O ILE T 36 N ILE T 29
SHEET 1 AF 6 ILE V 73 SER V 80 0
SHEET 2 AF 6 THR V 86 LEU V 94 -1 O ILE V 88 N ILE V 79
SHEET 3 AF 6 LYS V 105 HIS V 113 -1 O ARG V 106 N TYR V 93
SHEET 4 AF 6 PHE V 140 VAL V 145 1 O PHE V 140 N HIS V 113
SHEET 5 AF 6 ILE V 125 GLY V 129 -1 N THR V 127 O LEU V 143
SHEET 6 AF 6 ILE V 73 SER V 80 -1 N GLY V 76 O VAL V 126
SHEET 1 AG 2 ILE X 93 VAL X 94 0
SHEET 2 AG 2 VAL X 105 GLU X 106 -1 O VAL X 105 N VAL X 94
SHEET 1 AH 2 SER Y 104 ARG Y 108 0
SHEET 2 AH 2 ALA Y 111 SER Y 116 -1 O HIS Y 114 N GLN Y 106
SHEET 1 AI 2 VAL Y 136 GLU Y 137 0
SHEET 2 AI 2 ARG Y 146 LEU Y 147 -1 O ARG Y 146 N GLU Y 137
SHEET 1 AJ 2 VAL Z 32 VAL Z 39 0
SHEET 2 AJ 2 TYR Z 45 ILE Z 54 -1 O GLU Z 50 N VAL Z 36
SHEET 1 AK 4 THR 1 6 ASN 1 15 0
SHEET 2 AK 4 ARG 1 20 LEU 1 28 -1 O GLU 1 26 N ARG 1 8
SHEET 3 AK 4 LYS 1 71 TYR 1 77 -1 O ILE 1 76 N LYS 1 21
SHEET 4 AK 4 ILE 1 56 LYS 1 62 -1 N VAL 1 57 O LEU 1 75
SHEET 1 AL 2 PRO 3 20 ARG 3 22 0
SHEET 2 AL 2 CYS 3 29 PRO 3 31 -1 O VAL 3 30 N LEU 3 21
SHEET 1 AM 2 ILE 3 36 ARG 3 38 0
SHEET 2 AM 2 GLN 3 71 TYR 3 73 -1 O GLN 3 71 N ARG 3 38
SHEET 1 AN 2 ILE 3 41 ASN 3 43 0
SHEET 2 AN 2 LYS 3 66 TYR 3 68 -1 O LEU 3 67 N ARG 3 42
SHEET 1 AO 3 LEU 4 44 PHE 4 45 0
SHEET 2 AO 3 PHE 4 30 LYS 4 34 -1 N MET 4 31 O LEU 4 44
SHEET 3 AO 3 SER 4 76 LYS 4 79 -1 O ARG 4 78 N ASP 4 32
SHEET 1 AP 4 LEU 5 40 VAL 5 44 0
SHEET 2 AP 4 ILE 5 23 GLN 5 28 -1 N VAL 5 25 O ARG 5 42
SHEET 3 AP 4 LYS 5 5 GLY 5 14 -1 N LYS 5 11 O ARG 5 26
SHEET 4 AP 4 ILE 5 53 LEU 5 56 -1 O LEU 5 56 N LYS 5 5
SSBOND 1 CYS 3 26 CYS 3 77 1555 1555 2.04
LINK OP1 A A 169 MG MG A2155 1555 1555 1.72
LINK OP2 A A 998 MG MG A2140 1555 1555 1.82
LINK OP2 C A 170 MG MG A2155 1555 1555 1.85
LINK OP2 U A 103 MG MG A2104 1555 1555 1.85
LINK OP2 A A2054 MG MG A2151 1555 1555 1.88
LINK OP2 A A1094 MG MG A2145 1555 1555 1.91
LINK OP1 G A 16 MG MG A2102 1555 1555 1.93
LINK OP2 U A1405 MG MG A2154 1555 1555 1.94
LINK OP2 C A1306 MG MG A2164 1555 1555 1.94
LINK OP2 G A1211 MG MG A2146 1555 1555 1.94
LINK OP1 U A2063 MG MG A2149 1555 1555 1.97
LINK OP2 A A1047 MG MG A2143 1555 1555 1.98
LINK OP1 U A1927 MG MG A2148 1555 1555 2.00
LINK OP2 G A1430 MG MG A2162 1555 1555 2.01
LINK OP1 C A 621 MG MG A2127 1555 1555 2.02
LINK OP2 A A 628 MG MG A2128 1555 1555 2.07
LINK OP1 A A 102 MG MG A2103 1555 1555 2.08
LINK OP1 A A 28 MG MG A2120 1555 1555 2.08
LINK OP2 A A 407 MG MG A2117 1555 1555 2.09
LINK OP2 C A 367 MG MG A2104 1555 1555 2.09
LINK OP2 A A 627 MG MG A2128 1555 1555 2.10
LINK OP2 C A 430 MG MG A2118 1555 1555 2.10
LINK OP2 A A1930 MG MG A2101 1555 1555 2.11
LINK OP2 A A1261 MG MG A2147 1555 1555 2.12
LINK OP2 C A1375 MG MG A2163 1555 1555 2.15
LINK O6 G A1432 MG MG A2162 1555 1555 2.16
LINK OP2 C A 49 MG MG A2105 1555 1555 2.16
LINK OP1 A A1074 MG MG A2158 1555 1555 2.17
LINK OP2 G A1063 MG MG A2159 1555 1555 2.17
LINK OP1 A A 459 MG MG A2107 1555 1555 2.17
LINK OP2 A A 626 MG MG A2128 1555 1555 2.18
LINK OP1 G A1876 MG MG A2147 1555 1555 2.20
LINK OP1 C A 630 MG MG A2129 1555 1555 2.20
LINK OP2 A A 562 MG MG A2157 1555 1555 2.20
LINK OP2 A A 931 MG MG A2133 1555 1555 2.20
LINK OP1 U A 100 MG MG A2113 1555 1555 2.21
LINK OP2 A A 466 MG MG A2119 1555 1555 2.21
LINK OP1 G A 522 MG MG A2121 1555 1555 2.22
LINK O6 G A1701 MG MG A2164 1555 1555 2.22
LINK OP1 G A2060 MG MG A2149 1555 1555 2.23
LINK OP2 A A 563 MG MG A2157 1555 1555 2.24
LINK OP1 G A1302 MG MG A2167 1555 1555 2.25
LINK OP2 G A 467 MG MG A2119 1555 1555 2.26
LINK OP2 G A 97 MG MG A2109 1555 1555 2.26
LINK OP2 U A 385 MG MG A2116 1555 1555 2.26
LINK OP2 G A1432 MG MG A2161 1555 1555 2.26
LINK OP1 C A 632 MG MG A2130 1555 1555 2.26
LINK OP1 U A1703 MG MG A2166 1555 1555 2.27
LINK O4 U A 408 MG MG A2156 1555 1555 2.29
LINK OP1 A A 642 MG MG A2132 1555 1555 2.32
LINK OP2 U A1037 MG MG A2144 1555 1555 2.32
LINK OP2 A A2055 MG MG A2151 1555 1555 2.32
LINK OP1 A A 47 MG MG A2114 1555 1555 2.33
LINK OP1 A A 612 MG MG A2126 1555 1555 2.34
LINK OP1 U A1084 MG MG A2160 1555 1555 2.34
LINK OP2 A A 643 MG MG A2132 1555 1555 2.36
LINK O6 G A 964 MG MG A2139 1555 1555 2.39
LINK OP2 U A2062 MG MG A2150 1555 1555 2.40
LINK OP2 C A 630 MG MG A2130 1555 1555 2.40
LINK OP2 A A 384 MG MG A2116 1555 1555 2.41
LINK OP2 A A1304 MG MG A2165 1555 1555 2.41
LINK OP1 A A 614 MG MG A2126 1555 1555 2.43
LINK OP2 A A 611 MG MG A2125 1555 1555 2.44
LINK OP2 A A 637 MG MG A2131 1555 1555 2.44
LINK SG CYS T 40 ZN ZN T 100 1555 1555 2.50
LINK O4 U A 986 MG MG A2139 1555 1555 2.51
LINK O4 U A1307 MG MG A2164 1555 1555 2.52
LINK O4 U A 454 MG MG A2106 1555 1555 2.52
LINK OP1 A A2055 MG MG A2149 1555 1555 2.54
LINK OP2 A A 102 MG MG A2104 1555 1555 2.55
LINK OP1 A A1303 MG MG A2165 1555 1555 2.57
LINK SG CYS T 37 ZN ZN T 100 1555 1555 2.58
LINK OP1 G A2085 MG MG A2148 1555 1555 2.59
LINK OP2 G A1007 MG MG A2135 1555 1555 2.61
LINK OP1 G A1210 MG MG A2146 1555 1555 2.66
LINK OP2 G A2060 MG MG A2151 1555 1555 2.67
LINK SG CYS T 22 ZN ZN T 100 1555 1555 2.73
LINK OP2 U A 408 MG MG A2111 1555 1555 2.74
LINK OP2 A A 984 MG MG A2139 1555 1555 2.79
LINK OP2 G A1674 MG MG A2163 1555 1555 2.79
LINK OP2 A A 87 MG MG A2108 1555 1555 2.80
LINK OP1 A A1305 MG MG A2164 1555 1555 2.83
LINK O2' G A1374 MG MG A2163 1555 1555 2.89
LINK OP2 A A1074 MG MG A2159 1555 1555 2.94
LINK SG CYS T 19 ZN ZN T 100 1555 1555 2.95
LINK OP2 G A 578 MG MG A2124 1555 1555 2.95
LINK O3' G A 983 MG MG A2139 1555 1555 2.95
SITE 1 AC1 2 G A 10 A A1930
SITE 1 AC2 1 G A 16
SITE 1 AC3 2 A A 102 C A 367
SITE 1 AC4 5 A A 102 U A 103 U A 104 A A 366
SITE 2 AC4 5 C A 367
SITE 1 AC5 2 C A 49 A A 431
SITE 1 AC6 2 A A 452 U A 454
SITE 1 AC7 2 A A 60 A A 459
SITE 1 AC8 1 A A 87
SITE 1 AC9 1 G A 97
SITE 1 BC1 1 U A 408
SITE 1 BC2 3 G A 328 G A 343 A A 347
SITE 1 BC3 3 G A 42 A A 43 U A 100
SITE 1 BC4 2 U A 44 A A 47
SITE 1 BC5 1 G A 435
SITE 1 BC6 3 G A 383 A A 384 U A 385
SITE 1 BC7 2 A A 407 U A 408
SITE 1 BC8 2 C A 430 G A 432
SITE 1 BC9 2 A A 466 G A 467
SITE 1 CC1 1 A A 28
SITE 1 CC2 3 U A 35 G A 522 C A 537
SITE 1 CC3 1 G A 568
SITE 1 CC4 2 A A 577 G A 578
SITE 1 CC5 1 A A 611
SITE 1 CC6 3 G A 377 A A 612 A A 614
SITE 1 CC7 1 C A 621
SITE 1 CC8 4 U A 625 A A 626 A A 627 A A 628
SITE 1 CC9 1 C A 630
SITE 1 DC1 4 A A 629 C A 630 C A 632 U A1100
SITE 1 DC2 2 A A 637 G A 638
SITE 1 DC3 2 A A 642 A A 643
SITE 1 DC4 2 A A 930 A A 931
SITE 1 DC5 1 G A1007
SITE 1 DC6 3 U A1059 G A1060 G A1080
SITE 1 DC7 1 U A1081
SITE 1 DC8 1 G A1054
SITE 1 DC9 5 G A 964 U A 965 G A 983 A A 984
SITE 2 DC9 5 U A 986
SITE 1 EC1 2 G A 997 A A 998
SITE 1 EC2 1 G A 945
SITE 1 EC3 2 GLY 3 16 G A1011
SITE 1 EC4 1 A A1047
SITE 1 EC5 1 U A1037
SITE 1 EC6 1 A A1094
SITE 1 EC7 2 G A1210 G A1211
SITE 1 EC8 3 A A1261 G A1876 TYR M 143
SITE 1 EC9 3 G A1926 U A1927 G A2085
SITE 1 FC1 5 A A2055 G A2059 G A2060 U A2062
SITE 2 FC1 5 U A2063
SITE 1 FC2 1 U A2062
SITE 1 FC3 5 U A2053 A A2054 A A2055 G A2059
SITE 2 FC3 5 G A2060
SITE 1 FC4 2 G A 20 U A 21
SITE 1 FC5 1 G A 521
SITE 1 FC6 2 U A1405 G A1406
SITE 1 FC7 2 A A 169 C A 170
SITE 1 FC8 2 G A 394 U A 408
SITE 1 FC9 5 G A 559 G A 560 C A 561 A A 562
SITE 2 FC9 5 A A 563
SITE 1 GC1 3 A A1062 A A1074 MG A2159
SITE 1 GC2 3 G A1063 A A1074 MG A2158
SITE 1 GC3 1 U A1084
SITE 1 GC4 1 G A1432
SITE 1 GC5 2 G A1430 G A1432
SITE 1 GC6 4 G A1374 C A1375 G A1674 G A1675
SITE 1 GC7 4 A A1305 C A1306 U A1307 G A1701
SITE 1 GC8 3 A A1303 A A1304 C A1896
SITE 1 GC9 1 U A1703
SITE 1 HC1 1 G A1302
SITE 1 HC2 6 G A 973 U A1068 C A1075 G A2060
SITE 2 HC2 6 U A2061 LEU P 151
SITE 1 HC3 5 CYS T 19 CYS T 22 ASN T 24 CYS T 37
SITE 2 HC3 5 CYS T 40
CRYST1 1.000 1.000 1.000 90.00 90.00 90.00 P 1 1
ORIGX1 1.000000 0.000000 0.000000 0.00000
ORIGX2 0.000000 1.000000 0.000000 0.00000
ORIGX3 0.000000 0.000000 1.000000 0.00000
SCALE1 1.000000 0.000000 0.000000 0.00000
SCALE2 0.000000 1.000000 0.000000 0.00000
SCALE3 0.000000 0.000000 1.000000 0.00000
(ATOM LINES ARE NOT SHOWN.)
END
