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Database: PDB
Entry: 3JAQ
LinkDB: 3JAQ
Original site: 3JAQ 
HEADER    TRANSLATION                             18-JUN-15   3JAQ              
TITLE     STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX IN OPEN        
TITLE    2 CONFORMATION                                                         
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: MET-TRNAI;                                                 
COMPND   3 CHAIN: 1;                                                            
COMPND   4 ENGINEERED: YES;                                                     
COMPND   5 MOL_ID: 2;                                                           
COMPND   6 MOLECULE: 18S RRNA;                                                  
COMPND   7 CHAIN: 2;                                                            
COMPND   8 MOL_ID: 3;                                                           
COMPND   9 MOLECULE: MRNA;                                                      
COMPND  10 CHAIN: 3;                                                            
COMPND  11 ENGINEERED: YES;                                                     
COMPND  12 MOL_ID: 4;                                                           
COMPND  13 MOLECULE: US2;                                                       
COMPND  14 CHAIN: A;                                                            
COMPND  15 MOL_ID: 5;                                                           
COMPND  16 MOLECULE: ES1;                                                       
COMPND  17 CHAIN: B;                                                            
COMPND  18 MOL_ID: 6;                                                           
COMPND  19 MOLECULE: US5;                                                       
COMPND  20 CHAIN: C;                                                            
COMPND  21 MOL_ID: 7;                                                           
COMPND  22 MOLECULE: US3;                                                       
COMPND  23 CHAIN: D;                                                            
COMPND  24 MOL_ID: 8;                                                           
COMPND  25 MOLECULE: ES4;                                                       
COMPND  26 CHAIN: E;                                                            
COMPND  27 MOL_ID: 9;                                                           
COMPND  28 MOLECULE: US7;                                                       
COMPND  29 CHAIN: F;                                                            
COMPND  30 MOL_ID: 10;                                                          
COMPND  31 MOLECULE: ES6;                                                       
COMPND  32 CHAIN: G;                                                            
COMPND  33 MOL_ID: 11;                                                          
COMPND  34 MOLECULE: ES7;                                                       
COMPND  35 CHAIN: H;                                                            
COMPND  36 MOL_ID: 12;                                                          
COMPND  37 MOLECULE: ES8;                                                       
COMPND  38 CHAIN: I;                                                            
COMPND  39 MOL_ID: 13;                                                          
COMPND  40 MOLECULE: US4;                                                       
COMPND  41 CHAIN: J;                                                            
COMPND  42 MOL_ID: 14;                                                          
COMPND  43 MOLECULE: ES10;                                                      
COMPND  44 CHAIN: K;                                                            
COMPND  45 MOL_ID: 15;                                                          
COMPND  46 MOLECULE: US17;                                                      
COMPND  47 CHAIN: L;                                                            
COMPND  48 MOL_ID: 16;                                                          
COMPND  49 MOLECULE: ES12;                                                      
COMPND  50 CHAIN: M;                                                            
COMPND  51 MOL_ID: 17;                                                          
COMPND  52 MOLECULE: US15;                                                      
COMPND  53 CHAIN: N;                                                            
COMPND  54 MOL_ID: 18;                                                          
COMPND  55 MOLECULE: US11;                                                      
COMPND  56 CHAIN: O;                                                            
COMPND  57 MOL_ID: 19;                                                          
COMPND  58 MOLECULE: US19;                                                      
COMPND  59 CHAIN: P;                                                            
COMPND  60 MOL_ID: 20;                                                          
COMPND  61 MOLECULE: US9;                                                       
COMPND  62 CHAIN: Q;                                                            
COMPND  63 MOL_ID: 21;                                                          
COMPND  64 MOLECULE: ES17;                                                      
COMPND  65 CHAIN: R;                                                            
COMPND  66 MOL_ID: 22;                                                          
COMPND  67 MOLECULE: US13;                                                      
COMPND  68 CHAIN: S;                                                            
COMPND  69 MOL_ID: 23;                                                          
COMPND  70 MOLECULE: ES19;                                                      
COMPND  71 CHAIN: T;                                                            
COMPND  72 MOL_ID: 24;                                                          
COMPND  73 MOLECULE: US10;                                                      
COMPND  74 CHAIN: U;                                                            
COMPND  75 MOL_ID: 25;                                                          
COMPND  76 MOLECULE: ES21;                                                      
COMPND  77 CHAIN: V;                                                            
COMPND  78 MOL_ID: 26;                                                          
COMPND  79 MOLECULE: US8;                                                       
COMPND  80 CHAIN: W;                                                            
COMPND  81 MOL_ID: 27;                                                          
COMPND  82 MOLECULE: US12;                                                      
COMPND  83 CHAIN: X;                                                            
COMPND  84 MOL_ID: 28;                                                          
COMPND  85 MOLECULE: ES24;                                                      
COMPND  86 CHAIN: Y;                                                            
COMPND  87 MOL_ID: 29;                                                          
COMPND  88 MOLECULE: ES25;                                                      
COMPND  89 CHAIN: Z;                                                            
COMPND  90 MOL_ID: 30;                                                          
COMPND  91 MOLECULE: ES26;                                                      
COMPND  92 CHAIN: a;                                                            
COMPND  93 MOL_ID: 31;                                                          
COMPND  94 MOLECULE: ES27;                                                      
COMPND  95 CHAIN: b;                                                            
COMPND  96 MOL_ID: 32;                                                          
COMPND  97 MOLECULE: ES28;                                                      
COMPND  98 CHAIN: c;                                                            
COMPND  99 MOL_ID: 33;                                                          
COMPND 100 MOLECULE: US14;                                                      
COMPND 101 CHAIN: d;                                                            
COMPND 102 MOL_ID: 34;                                                          
COMPND 103 MOLECULE: ES30;                                                      
COMPND 104 CHAIN: e;                                                            
COMPND 105 MOL_ID: 35;                                                          
COMPND 106 MOLECULE: ES31;                                                      
COMPND 107 CHAIN: f;                                                            
COMPND 108 MOL_ID: 36;                                                          
COMPND 109 MOLECULE: RACK1;                                                     
COMPND 110 CHAIN: g;                                                            
COMPND 111 MOL_ID: 37;                                                          
COMPND 112 MOLECULE: EL41;                                                      
COMPND 113 CHAIN: h;                                                            
COMPND 114 MOL_ID: 38;                                                          
COMPND 115 MOLECULE: EIF1A;                                                     
COMPND 116 CHAIN: i;                                                            
COMPND 117 ENGINEERED: YES;                                                     
COMPND 118 MOL_ID: 39;                                                          
COMPND 119 MOLECULE: EIF2 ALPHA;                                                
COMPND 120 CHAIN: j;                                                            
COMPND 121 ENGINEERED: YES;                                                     
COMPND 122 MOL_ID: 40;                                                          
COMPND 123 MOLECULE: EIF2 GAMMA;                                                
COMPND 124 CHAIN: k;                                                            
COMPND 125 ENGINEERED: YES;                                                     
COMPND 126 MOL_ID: 41;                                                          
COMPND 127 MOLECULE: EIF2 BETA;                                                 
COMPND 128 CHAIN: l;                                                            
COMPND 129 ENGINEERED: YES;                                                     
COMPND 130 MOL_ID: 42;                                                          
COMPND 131 MOLECULE: EIF1;                                                      
COMPND 132 CHAIN: m;                                                            
COMPND 133 ENGINEERED: YES;                                                     
COMPND 134 MOL_ID: 43;                                                          
COMPND 135 MOLECULE: EIF3A;                                                     
COMPND 136 CHAIN: o;                                                            
COMPND 137 ENGINEERED: YES;                                                     
COMPND 138 MOL_ID: 44;                                                          
COMPND 139 MOLECULE: EIF3C;                                                     
COMPND 140 CHAIN: p;                                                            
COMPND 141 ENGINEERED: YES;                                                     
COMPND 142 MOL_ID: 45;                                                          
COMPND 143 MOLECULE: EIF3I;                                                     
COMPND 144 CHAIN: q;                                                            
COMPND 145 ENGINEERED: YES;                                                     
COMPND 146 MOL_ID: 46;                                                          
COMPND 147 MOLECULE: EIF3B;                                                     
COMPND 148 CHAIN: r;                                                            
COMPND 149 ENGINEERED: YES;                                                     
COMPND 150 MOL_ID: 47;                                                          
COMPND 151 MOLECULE: EIF3G;                                                     
COMPND 152 CHAIN: s;                                                            
COMPND 153 ENGINEERED: YES                                                      
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE   3 ORGANISM_COMMON: YEAST;                                              
SOURCE   4 ORGANISM_TAXID: 4932;                                                
SOURCE   5 EXPRESSION_SYSTEM: SACCHAROMYCES CEREVISIAE;                         
SOURCE   6 EXPRESSION_SYSTEM_COMMON: YEAST;                                     
SOURCE   7 EXPRESSION_SYSTEM_TAXID: 4932;                                       
SOURCE   8 MOL_ID: 2;                                                           
SOURCE   9 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  10 ORGANISM_TAXID: 28985;                                               
SOURCE  11 MOL_ID: 3;                                                           
SOURCE  12 SYNTHETIC: YES;                                                      
SOURCE  13 ORGANISM_SCIENTIFIC: SYNTHETIC CONSTRUCT;                            
SOURCE  14 ORGANISM_TAXID: 32630;                                               
SOURCE  15 MOL_ID: 4;                                                           
SOURCE  16 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  17 ORGANISM_TAXID: 28985;                                               
SOURCE  18 MOL_ID: 5;                                                           
SOURCE  19 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  20 ORGANISM_TAXID: 28985;                                               
SOURCE  21 MOL_ID: 6;                                                           
SOURCE  22 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  23 ORGANISM_TAXID: 28985;                                               
SOURCE  24 MOL_ID: 7;                                                           
SOURCE  25 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  26 ORGANISM_TAXID: 28985;                                               
SOURCE  27 MOL_ID: 8;                                                           
SOURCE  28 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  29 ORGANISM_TAXID: 28985;                                               
SOURCE  30 MOL_ID: 9;                                                           
SOURCE  31 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  32 ORGANISM_TAXID: 28985;                                               
SOURCE  33 MOL_ID: 10;                                                          
SOURCE  34 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  35 ORGANISM_TAXID: 28985;                                               
SOURCE  36 MOL_ID: 11;                                                          
SOURCE  37 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  38 ORGANISM_TAXID: 28985;                                               
SOURCE  39 MOL_ID: 12;                                                          
SOURCE  40 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  41 ORGANISM_TAXID: 28985;                                               
SOURCE  42 MOL_ID: 13;                                                          
SOURCE  43 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  44 ORGANISM_TAXID: 28985;                                               
SOURCE  45 MOL_ID: 14;                                                          
SOURCE  46 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  47 ORGANISM_TAXID: 28985;                                               
SOURCE  48 MOL_ID: 15;                                                          
SOURCE  49 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  50 ORGANISM_TAXID: 28985;                                               
SOURCE  51 MOL_ID: 16;                                                          
SOURCE  52 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  53 ORGANISM_TAXID: 28985;                                               
SOURCE  54 MOL_ID: 17;                                                          
SOURCE  55 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  56 ORGANISM_TAXID: 28985;                                               
SOURCE  57 MOL_ID: 18;                                                          
SOURCE  58 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  59 ORGANISM_TAXID: 28985;                                               
SOURCE  60 MOL_ID: 19;                                                          
SOURCE  61 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  62 ORGANISM_TAXID: 28985;                                               
SOURCE  63 MOL_ID: 20;                                                          
SOURCE  64 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  65 ORGANISM_TAXID: 28985;                                               
SOURCE  66 MOL_ID: 21;                                                          
SOURCE  67 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  68 ORGANISM_TAXID: 28985;                                               
SOURCE  69 MOL_ID: 22;                                                          
SOURCE  70 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  71 ORGANISM_TAXID: 28985;                                               
SOURCE  72 MOL_ID: 23;                                                          
SOURCE  73 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  74 ORGANISM_TAXID: 28985;                                               
SOURCE  75 MOL_ID: 24;                                                          
SOURCE  76 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  77 ORGANISM_TAXID: 28985;                                               
SOURCE  78 MOL_ID: 25;                                                          
SOURCE  79 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  80 ORGANISM_TAXID: 28985;                                               
SOURCE  81 MOL_ID: 26;                                                          
SOURCE  82 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  83 ORGANISM_TAXID: 28985;                                               
SOURCE  84 MOL_ID: 27;                                                          
SOURCE  85 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  86 ORGANISM_TAXID: 28985;                                               
SOURCE  87 MOL_ID: 28;                                                          
SOURCE  88 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  89 ORGANISM_TAXID: 28985;                                               
SOURCE  90 MOL_ID: 29;                                                          
SOURCE  91 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  92 ORGANISM_TAXID: 28985;                                               
SOURCE  93 MOL_ID: 30;                                                          
SOURCE  94 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  95 ORGANISM_TAXID: 28985;                                               
SOURCE  96 MOL_ID: 31;                                                          
SOURCE  97 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE  98 ORGANISM_TAXID: 28985;                                               
SOURCE  99 MOL_ID: 32;                                                          
SOURCE 100 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE 101 ORGANISM_TAXID: 28985;                                               
SOURCE 102 MOL_ID: 33;                                                          
SOURCE 103 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE 104 ORGANISM_TAXID: 28985;                                               
SOURCE 105 MOL_ID: 34;                                                          
SOURCE 106 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE 107 ORGANISM_TAXID: 28985;                                               
SOURCE 108 MOL_ID: 35;                                                          
SOURCE 109 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE 110 ORGANISM_TAXID: 28985;                                               
SOURCE 111 MOL_ID: 36;                                                          
SOURCE 112 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE 113 ORGANISM_TAXID: 28985;                                               
SOURCE 114 MOL_ID: 37;                                                          
SOURCE 115 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;                           
SOURCE 116 ORGANISM_TAXID: 28985;                                               
SOURCE 117 MOL_ID: 38;                                                          
SOURCE 118 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE 119 ORGANISM_COMMON: YEAST;                                              
SOURCE 120 ORGANISM_TAXID: 4932;                                                
SOURCE 121 EXPRESSION_SYSTEM: ESCHERICHIA COLI BL21;                            
SOURCE 122 EXPRESSION_SYSTEM_TAXID: 511693;                                     
SOURCE 123 EXPRESSION_SYSTEM_STRAIN: ROSETTA;                                   
SOURCE 124 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                              
SOURCE 125 EXPRESSION_SYSTEM_PLASMID: PTYB2;                                    
SOURCE 126 MOL_ID: 39;                                                          
SOURCE 127 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE 128 ORGANISM_COMMON: YEAST;                                              
SOURCE 129 ORGANISM_TAXID: 4932;                                                
SOURCE 130 EXPRESSION_SYSTEM: SACCHAROMYCES CEREVISIAE;                         
SOURCE 131 EXPRESSION_SYSTEM_COMMON: YEAST;                                     
SOURCE 132 EXPRESSION_SYSTEM_TAXID: 4932;                                       
SOURCE 133 MOL_ID: 40;                                                          
SOURCE 134 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE 135 ORGANISM_COMMON: YEAST;                                              
SOURCE 136 ORGANISM_TAXID: 4932;                                                
SOURCE 137 EXPRESSION_SYSTEM: SACCHAROMYCES CEREVISIAE;                         
SOURCE 138 EXPRESSION_SYSTEM_COMMON: YEAST;                                     
SOURCE 139 EXPRESSION_SYSTEM_TAXID: 4932;                                       
SOURCE 140 MOL_ID: 41;                                                          
SOURCE 141 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE 142 ORGANISM_COMMON: YEAST;                                              
SOURCE 143 ORGANISM_TAXID: 4932;                                                
SOURCE 144 EXPRESSION_SYSTEM: SACCHAROMYCES CEREVISIAE;                         
SOURCE 145 EXPRESSION_SYSTEM_COMMON: YEAST;                                     
SOURCE 146 EXPRESSION_SYSTEM_TAXID: 4932;                                       
SOURCE 147 MOL_ID: 42;                                                          
SOURCE 148 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE 149 ORGANISM_COMMON: YEAST;                                              
SOURCE 150 ORGANISM_TAXID: 4932;                                                
SOURCE 151 EXPRESSION_SYSTEM: ESCHERICHIA COLI BL21;                            
SOURCE 152 EXPRESSION_SYSTEM_TAXID: 511693;                                     
SOURCE 153 EXPRESSION_SYSTEM_STRAIN: ROSETTA;                                   
SOURCE 154 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                              
SOURCE 155 EXPRESSION_SYSTEM_PLASMID: PTYB2;                                    
SOURCE 156 MOL_ID: 43;                                                          
SOURCE 157 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE 158 ORGANISM_COMMON: YEAST;                                              
SOURCE 159 ORGANISM_TAXID: 4932;                                                
SOURCE 160 EXPRESSION_SYSTEM: ESCHERICHIA COLI BL21;                            
SOURCE 161 EXPRESSION_SYSTEM_TAXID: 511693;                                     
SOURCE 162 EXPRESSION_SYSTEM_STRAIN: ROSETTA;                                   
SOURCE 163 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                              
SOURCE 164 EXPRESSION_SYSTEM_PLASMID: PCDFDUET;                                 
SOURCE 165 MOL_ID: 44;                                                          
SOURCE 166 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE 167 ORGANISM_COMMON: YEAST;                                              
SOURCE 168 ORGANISM_TAXID: 4932;                                                
SOURCE 169 EXPRESSION_SYSTEM: ESCHERICHIA COLI BL21;                            
SOURCE 170 EXPRESSION_SYSTEM_TAXID: 511693;                                     
SOURCE 171 EXPRESSION_SYSTEM_STRAIN: ROSETTA;                                   
SOURCE 172 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                              
SOURCE 173 EXPRESSION_SYSTEM_PLASMID: PCDFDUET;                                 
SOURCE 174 MOL_ID: 45;                                                          
SOURCE 175 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE 176 ORGANISM_COMMON: YEAST;                                              
SOURCE 177 ORGANISM_TAXID: 4932;                                                
SOURCE 178 EXPRESSION_SYSTEM: ESCHERICHIA COLI BL21;                            
SOURCE 179 EXPRESSION_SYSTEM_TAXID: 511693;                                     
SOURCE 180 EXPRESSION_SYSTEM_STRAIN: ROSETTA;                                   
SOURCE 181 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                              
SOURCE 182 EXPRESSION_SYSTEM_PLASMID: PQLINK;                                   
SOURCE 183 MOL_ID: 46;                                                          
SOURCE 184 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE 185 ORGANISM_COMMON: YEAST;                                              
SOURCE 186 ORGANISM_TAXID: 4932;                                                
SOURCE 187 EXPRESSION_SYSTEM: ESCHERICHIA COLI BL21;                            
SOURCE 188 EXPRESSION_SYSTEM_TAXID: 511693;                                     
SOURCE 189 EXPRESSION_SYSTEM_STRAIN: ROSETTA;                                   
SOURCE 190 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                              
SOURCE 191 EXPRESSION_SYSTEM_PLASMID: PQLINK;                                   
SOURCE 192 MOL_ID: 47;                                                          
SOURCE 193 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE 194 ORGANISM_COMMON: YEAST;                                              
SOURCE 195 ORGANISM_TAXID: 4932;                                                
SOURCE 196 EXPRESSION_SYSTEM: ESCHERICHIA COLI BL21;                            
SOURCE 197 EXPRESSION_SYSTEM_TAXID: 511693;                                     
SOURCE 198 EXPRESSION_SYSTEM_STRAIN: ROSETTA;                                   
SOURCE 199 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                              
SOURCE 200 EXPRESSION_SYSTEM_PLASMID: PQLINK                                    
KEYWDS    EUKARYOTIC TRANSLATION INITIATION, 48S, SMALL RIBOSOME SUBUNIT, 40S,  
KEYWDS   2 43S, TRANSLATION                                                     
EXPDTA    ELECTRON MICROSCOPY                                                   
AUTHOR    J.L.LLACER,T.HUSSAIN,V.RAMAKRISHNAN                                   
REVDAT   3   18-JUL-18 3JAQ    1       REMARK                                   
REVDAT   2   02-SEP-15 3JAQ    1       JRNL                                     
REVDAT   1   12-AUG-15 3JAQ    0                                                
JRNL        AUTH   J.L.LLACER,T.HUSSAIN,L.MARLER,C.E.AITKEN,A.THAKUR,           
JRNL        AUTH 2 J.R.LORSCH,A.G.HINNEBUSCH,V.RAMAKRISHNAN                     
JRNL        TITL   CONFORMATIONAL DIFFERENCES BETWEEN OPEN AND CLOSED STATES OF 
JRNL        TITL 2 THE EUKARYOTIC TRANSLATION INITIATION COMPLEX.               
JRNL        REF    MOL.CELL                      V.  59   399 2015              
JRNL        REFN                   ISSN 1097-2765                               
JRNL        PMID   26212456                                                     
JRNL        DOI    10.1016/J.MOLCEL.2015.06.033                                 
REMARK   2                                                                      
REMARK   2 RESOLUTION.    6.00 ANGSTROMS.                                       
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   SOFTWARE PACKAGES      : COOT, REFMAC, UCSF CHIMERA, RELION        
REMARK   3   RECONSTRUCTION SCHEMA  : NULL                                      
REMARK   3                                                                      
REMARK   3 EM MAP-MODEL FITTING AND REFINEMENT                                  
REMARK   3   PDB ENTRY                    : 3J81                                
REMARK   3   REFINEMENT SPACE             : RECIPROCAL                          
REMARK   3   REFINEMENT PROTOCOL          : OTHER                               
REMARK   3   REFINEMENT TARGET            : RFACTOR, FSC                        
REMARK   3   OVERALL ANISOTROPIC B VALUE  : NULL                                
REMARK   3                                                                      
REMARK   3 FITTING PROCEDURE : METHOD--LOCAL REFINEMENT                         
REMARK   3                                                                      
REMARK   3 EM IMAGE RECONSTRUCTION STATISTICS                                   
REMARK   3   NOMINAL PIXEL SIZE (ANGSTROMS)    : 1.340                          
REMARK   3   ACTUAL PIXEL SIZE  (ANGSTROMS)    : NULL                           
REMARK   3   EFFECTIVE RESOLUTION (ANGSTROMS)  : 6.000                          
REMARK   3   NUMBER OF PARTICLES               : 4547                           
REMARK   3   CTF CORRECTION METHOD             : NULL                           
REMARK   3                                                                      
REMARK   3 EM RECONSTRUCTION MAGNIFICATION CALIBRATION: NULL                    
REMARK   3                                                                      
REMARK   3 OTHER DETAILS: GOLD-STANDARD                                         
REMARK   4                                                                      
REMARK   4 3JAQ COMPLIES WITH FORMAT V. 3.30, 13-JUL-11                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 10-JUL-15.                  
REMARK 100 THE DEPOSITION ID IS D_1000160464.                                   
REMARK 245                                                                      
REMARK 245 EXPERIMENTAL DETAILS                                                 
REMARK 245   RECONSTRUCTION METHOD          : SINGLE PARTICLE                   
REMARK 245   SPECIMEN TYPE                  : VITREOUS ICE (CRYO EM)            
REMARK 245                                                                      
REMARK 245 ELECTRON MICROSCOPE SAMPLE                                           
REMARK 245   SAMPLE TYPE                    : PARTICLE                          
REMARK 245   PARTICLE TYPE                  : POINT                             
REMARK 245   NAME OF SAMPLE                 : PARTIAL YEAST 48S PREINITIATION   
REMARK 245                                    COMPLEX IN OPEN CONFORMATION;     
REMARK 245                                    40S RIBOSOME; EUKARYOTIC          
REMARK 245                                    INITIATION FACTOR EIF1A;          
REMARK 245                                    EUKARYOTIC INITIATION FACTOR      
REMARK 245                                    EIF1; EUKARYOTIC INITIATION       
REMARK 245                                    FACTOR EIF2; EUKARYOTIC           
REMARK 245                                    INITIATION FACTOR EIF3; MET-      
REMARK 245                                    TRNAI; MRNA                       
REMARK 245   SAMPLE CONCENTRATION (MG ML-1) : 0.17                              
REMARK 245   SAMPLE SUPPORT DETAILS         : QUANTIFOIL R2/2 400 MESH COPPER   
REMARK 245                                    GRIDS WITH 4-5 NM THIN CARBON     
REMARK 245                                    ON TOP                            
REMARK 245   SAMPLE VITRIFICATION DETAILS   : BLOT FOR 2.5 TO 3 SECONDS         
REMARK 245                                    BEFORE PLUNGING INTO LIQUID       
REMARK 245                                    ETHANE (FEI VITROBOT MARK I).     
REMARK 245   SAMPLE BUFFER                  : 20 MM MES-KOH, 40 MM POTASSIUM    
REMARK 245                                    ACETATE, 10 MM AMMONIUM ACETATE,  
REMARK 245                                    8 MM MAGNESIUM ACETATE, 2 MM      
REMARK 245                                    DTT                               
REMARK 245   PH                             : 6.50                              
REMARK 245   SAMPLE DETAILS                 : NULL                              
REMARK 245                                                                      
REMARK 245 DATA ACQUISITION                                                     
REMARK 245   DATE OF EXPERIMENT                : 28-APR-14                      
REMARK 245   NUMBER OF MICROGRAPHS-IMAGES      : NULL                           
REMARK 245   TEMPERATURE (KELVIN)              : NULL                           
REMARK 245   MICROSCOPE MODEL                  : FEI TITAN KRIOS                
REMARK 245   DETECTOR TYPE                     : FEI FALCON II (4K X 4K)        
REMARK 245   MINIMUM DEFOCUS (NM)              : 4000.00                        
REMARK 245   MAXIMUM DEFOCUS (NM)              : 1500.00                        
REMARK 245   MINIMUM TILT ANGLE (DEGREES)      : NULL                           
REMARK 245   MAXIMUM TILT ANGLE (DEGREES)      : NULL                           
REMARK 245   NOMINAL CS                        : 2.70                           
REMARK 245   IMAGING MODE                      : BRIGHT FIELD                   
REMARK 245   ELECTRON DOSE (ELECTRONS NM**-2)  : 27.00                          
REMARK 245   ILLUMINATION MODE                 : FLOOD BEAM                     
REMARK 245   NOMINAL MAGNIFICATION             : 59000                          
REMARK 245   CALIBRATED MAGNIFICATION          : 104478                         
REMARK 245   SOURCE                            : FIELD EMISSION GUN             
REMARK 245   ACCELERATION VOLTAGE (KV)         : 300                            
REMARK 245   IMAGING DETAILS                   : COMPLETE DATASET WAS           
REMARK 245  COLLECTED OVER TWO NON-CONSECUTIVE DAYS.                            
REMARK 247                                                                      
REMARK 247 ELECTRON MICROSCOPY                                                  
REMARK 247  THE COORDINATES IN THIS ENTRY WERE GENERATED FROM ELECTRON          
REMARK 247  MICROSCOPY DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE              
REMARK 247  THAT CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES           
REMARK 247  ON THESE RECORDS ARE MEANINGLESS EXCEPT FOR THE CALCULATION         
REMARK 247  OF THE STRUCTURE FACTORS.                                           
REMARK 300                                                                      
REMARK 300 BIOMOLECULE: 1                                                       
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM                
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN                  
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON               
REMARK 300 BURIED SURFACE AREA.                                                 
REMARK 350                                                                      
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN           
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE                
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS          
REMARK 350 GIVEN BELOW.  BOTH NON-CRYSTALLOGRAPHIC AND                          
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.                               
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 1                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: 47-MERIC                          
REMARK 350 APPLY THE FOLLOWING TO CHAINS: 1, 2, 3, A, B, C, D, E, F, G,         
REMARK 350                    AND CHAINS: H, I, J, K, L, M, N, O, P,            
REMARK 350                    AND CHAINS: Q, R, S, T, U, V, W, X, Y, Z,         
REMARK 350                    AND CHAINS: a, b, c, d, e, f, g, h, i,            
REMARK 350                    AND CHAINS: j, k, l, m, o, p, q, r, s             
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 465                                                                      
REMARK 465 MISSING RESIDUES                                                     
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE                       
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)                
REMARK 465                                                                      
REMARK 465   M RES C SSSEQI                                                     
REMARK 465       C 2   675                                                      
REMARK 465       G 3    10                                                      
REMARK 465       G 3    11                                                      
REMARK 465       A 3    12                                                      
REMARK 465       C 3    15                                                      
REMARK 465       U 3    16                                                      
REMARK 465       C 3    17                                                      
REMARK 465       U 3    18                                                      
REMARK 465       C 3    19                                                      
REMARK 465       U 3    20                                                      
REMARK 465       C 3    21                                                      
REMARK 465       U 3    22                                                      
REMARK 465       A 3    23                                                      
REMARK 465       U 3    24                                                      
REMARK 465       C 3    25                                                      
REMARK 465       C 3    26                                                      
REMARK 465       U 3    27                                                      
REMARK 465       C 3    28                                                      
REMARK 465       U 3    29                                                      
REMARK 465       C 3    30                                                      
REMARK 465       U 3    31                                                      
REMARK 465       C 3    32                                                      
REMARK 465       U 3    33                                                      
REMARK 465       C 3    34                                                      
REMARK 465     MET A     1                                                      
REMARK 465     ILE A   210                                                      
REMARK 465     GLU A   211                                                      
REMARK 465     GLN A   212                                                      
REMARK 465     GLN A   213                                                      
REMARK 465     THR A   214                                                      
REMARK 465     ALA A   215                                                      
REMARK 465     GLU A   216                                                      
REMARK 465     GLU A   217                                                      
REMARK 465     GLU A   218                                                      
REMARK 465     ALA A   219                                                      
REMARK 465     VAL A   220                                                      
REMARK 465     ALA A   221                                                      
REMARK 465     SER A   222                                                      
REMARK 465     GLY A   223                                                      
REMARK 465     GLU A   224                                                      
REMARK 465     GLN A   225                                                      
REMARK 465     THR A   226                                                      
REMARK 465     GLU A   227                                                      
REMARK 465     GLU A   228                                                      
REMARK 465     ALA A   229                                                      
REMARK 465     VAL A   230                                                      
REMARK 465     ASP A   231                                                      
REMARK 465     ALA A   232                                                      
REMARK 465     THR A   233                                                      
REMARK 465     GLU A   234                                                      
REMARK 465     GLU A   235                                                      
REMARK 465     GLN A   236                                                      
REMARK 465     THR A   237                                                      
REMARK 465     GLU A   238                                                      
REMARK 465     ALA A   239                                                      
REMARK 465     ALA A   240                                                      
REMARK 465     GLU A   241                                                      
REMARK 465     TRP A   242                                                      
REMARK 465     ALA A   243                                                      
REMARK 465     GLU A   244                                                      
REMARK 465     GLU A   245                                                      
REMARK 465     GLY A   246                                                      
REMARK 465     GLN A   247                                                      
REMARK 465     ALA A   248                                                      
REMARK 465     GLN A   249                                                      
REMARK 465     GLU A   250                                                      
REMARK 465     GLU A   251                                                      
REMARK 465     GLU A   252                                                      
REMARK 465     TRP A   253                                                      
REMARK 465     ASN A   254                                                      
REMARK 465     MET B     1                                                      
REMARK 465     ALA B     2                                                      
REMARK 465     SER B    10                                                      
REMARK 465     LYS B    11                                                      
REMARK 465     GLY B    12                                                      
REMARK 465     LYS B    13                                                      
REMARK 465     LYS B    14                                                      
REMARK 465     GLY B    15                                                      
REMARK 465     LEU B    16                                                      
REMARK 465     LYS B    17                                                      
REMARK 465     LYS B    18                                                      
REMARK 465     GLU B   234                                                      
REMARK 465     ALA B   235                                                      
REMARK 465     SER B   236                                                      
REMARK 465     ALA B   237                                                      
REMARK 465     GLU B   238                                                      
REMARK 465     GLU B   239                                                      
REMARK 465     LYS B   240                                                      
REMARK 465     GLY B   241                                                      
REMARK 465     LYS B   242                                                      
REMARK 465     LYS B   243                                                      
REMARK 465     VAL B   244                                                      
REMARK 465     ALA B   245                                                      
REMARK 465     GLY B   246                                                      
REMARK 465     PHE B   247                                                      
REMARK 465     LYS B   248                                                      
REMARK 465     ASP B   249                                                      
REMARK 465     GLU B   250                                                      
REMARK 465     ILE B   251                                                      
REMARK 465     LEU B   252                                                      
REMARK 465     GLU B   253                                                      
REMARK 465     THR B   254                                                      
REMARK 465     VAL B   255                                                      
REMARK 465     MET C     1                                                      
REMARK 465     SER C     2                                                      
REMARK 465     ALA C     3                                                      
REMARK 465     PRO C     4                                                      
REMARK 465     GLN C     5                                                      
REMARK 465     ALA C     6                                                      
REMARK 465     GLN C     7                                                      
REMARK 465     GLY C     8                                                      
REMARK 465     GLN C     9                                                      
REMARK 465     GLN C    10                                                      
REMARK 465     ALA C    11                                                      
REMARK 465     PRO C    12                                                      
REMARK 465     ARG C    13                                                      
REMARK 465     ARG C    14                                                      
REMARK 465     GLY C    15                                                      
REMARK 465     GLY C    16                                                      
REMARK 465     PHE C    17                                                      
REMARK 465     GLY C    18                                                      
REMARK 465     GLY C    19                                                      
REMARK 465     ALA C    20                                                      
REMARK 465     ASN C    21                                                      
REMARK 465     ARG C    22                                                      
REMARK 465     GLY C    23                                                      
REMARK 465     GLY C    24                                                      
REMARK 465     ARG C    25                                                      
REMARK 465     GLY C    26                                                      
REMARK 465     GLY C    27                                                      
REMARK 465     ARG C    28                                                      
REMARK 465     ARG C    29                                                      
REMARK 465     GLY C    30                                                      
REMARK 465     GLY C    31                                                      
REMARK 465     ARG C    32                                                      
REMARK 465     ARG C    33                                                      
REMARK 465     ASP C    34                                                      
REMARK 465     GLN C    35                                                      
REMARK 465     GLU C    36                                                      
REMARK 465     GLU C    37                                                      
REMARK 465     LYS C    38                                                      
REMARK 465     LYS C   256                                                      
REMARK 465     LYS C   257                                                      
REMARK 465     LYS C   258                                                      
REMARK 465     LEU C   259                                                      
REMARK 465     MET D     1                                                      
REMARK 465     VAL D     2                                                      
REMARK 465     ARG D   226                                                      
REMARK 465     PRO D   227                                                      
REMARK 465     THR D   228                                                      
REMARK 465     GLU D   229                                                      
REMARK 465     PRO D   230                                                      
REMARK 465     VAL D   231                                                      
REMARK 465     GLU D   232                                                      
REMARK 465     ALA D   233                                                      
REMARK 465     ALA D   234                                                      
REMARK 465     GLU D   235                                                      
REMARK 465     SER D   236                                                      
REMARK 465     ALA D   237                                                      
REMARK 465     MET E     1                                                      
REMARK 465     MET F     1                                                      
REMARK 465     SER F     2                                                      
REMARK 465     GLU F     3                                                      
REMARK 465     HIS F     4                                                      
REMARK 465     GLU F     5                                                      
REMARK 465     ALA F     6                                                      
REMARK 465     GLN F     7                                                      
REMARK 465     VAL F     8                                                      
REMARK 465     GLU F     9                                                      
REMARK 465     VAL F    10                                                      
REMARK 465     GLU F    11                                                      
REMARK 465     VAL F    12                                                      
REMARK 465     GLN F    13                                                      
REMARK 465     GLU F    14                                                      
REMARK 465     ASP F    15                                                      
REMARK 465     PHE F    16                                                      
REMARK 465     GLU F    17                                                      
REMARK 465     VAL F    18                                                      
REMARK 465     VAL F    19                                                      
REMARK 465     GLN F    20                                                      
REMARK 465     GLU F    21                                                      
REMARK 465     ARG G   227                                                      
REMARK 465     LYS G   228                                                      
REMARK 465     ARG G   229                                                      
REMARK 465     ARG G   230                                                      
REMARK 465     ALA G   231                                                      
REMARK 465     SER G   232                                                      
REMARK 465     SER G   233                                                      
REMARK 465     LEU G   234                                                      
REMARK 465     LYS G   235                                                      
REMARK 465     ALA G   236                                                      
REMARK 465     MET H     1                                                      
REMARK 465     SER H     2                                                      
REMARK 465     ASP H     3                                                      
REMARK 465     GLU H   188                                                      
REMARK 465     THR H   189                                                      
REMARK 465     HIS H   190                                                      
REMARK 465     MET I     1                                                      
REMARK 465     LYS I   124                                                      
REMARK 465     LYS I   125                                                      
REMARK 465     ASN I   126                                                      
REMARK 465     THR I   127                                                      
REMARK 465     LYS I   128                                                      
REMARK 465     ALA I   129                                                      
REMARK 465     GLU I   130                                                      
REMARK 465     GLU I   131                                                      
REMARK 465     GLU I   132                                                      
REMARK 465     THR I   133                                                      
REMARK 465     ALA I   134                                                      
REMARK 465     THR I   135                                                      
REMARK 465     MET J     1                                                      
REMARK 465     GLU J   184                                                      
REMARK 465     ALA J   185                                                      
REMARK 465     ASP J   186                                                      
REMARK 465     GLU J   187                                                      
REMARK 465     GLU J   188                                                      
REMARK 465     GLY K    97                                                      
REMARK 465     ASP K    98                                                      
REMARK 465     GLN K    99                                                      
REMARK 465     ARG K   100                                                      
REMARK 465     PRO K   101                                                      
REMARK 465     GLN K   102                                                      
REMARK 465     GLY K   103                                                      
REMARK 465     LYS K   104                                                      
REMARK 465     LYS K   105                                                      
REMARK 465     TYR K   106                                                      
REMARK 465     MET L     1                                                      
REMARK 465     MET M     1                                                      
REMARK 465     SER M     2                                                      
REMARK 465     ASP M     3                                                      
REMARK 465     VAL M     4                                                      
REMARK 465     GLU M     5                                                      
REMARK 465     GLU M     6                                                      
REMARK 465     VAL M     7                                                      
REMARK 465     GLN M     8                                                      
REMARK 465     GLN M     9                                                      
REMARK 465     VAL M    10                                                      
REMARK 465     PRO M    11                                                      
REMARK 465     VAL M    12                                                      
REMARK 465     ALA M    13                                                      
REMARK 465     GLU M    14                                                      
REMARK 465     LEU M    15                                                      
REMARK 465     THR M    16                                                      
REMARK 465     ASN M    75                                                      
REMARK 465     MET N     1                                                      
REMARK 465     MET O     1                                                      
REMARK 465     ALA O     2                                                      
REMARK 465     ASN O     3                                                      
REMARK 465     VAL O     4                                                      
REMARK 465     VAL O     5                                                      
REMARK 465     GLN O     6                                                      
REMARK 465     ALA O     7                                                      
REMARK 465     LYS O     8                                                      
REMARK 465     ASP O     9                                                      
REMARK 465     ASN O    10                                                      
REMARK 465     MET P     1                                                      
REMARK 465     SER P     2                                                      
REMARK 465     GLU P     3                                                      
REMARK 465     ALA P     4                                                      
REMARK 465     ALA P     5                                                      
REMARK 465     ALA P     6                                                      
REMARK 465     PRO P     7                                                      
REMARK 465     ARG P     8                                                      
REMARK 465     LYS P     9                                                      
REMARK 465     ARG P    10                                                      
REMARK 465     SER P    11                                                      
REMARK 465     PHE P    12                                                      
REMARK 465     GLY P   132                                                      
REMARK 465     ALA P   133                                                      
REMARK 465     THR P   134                                                      
REMARK 465     THR P   135                                                      
REMARK 465     SER P   136                                                      
REMARK 465     ARG P   137                                                      
REMARK 465     PHE P   138                                                      
REMARK 465     ILE P   139                                                      
REMARK 465     PRO P   140                                                      
REMARK 465     LEU P   141                                                      
REMARK 465     ARG P   142                                                      
REMARK 465     MET Q     1                                                      
REMARK 465     SER Q     2                                                      
REMARK 465     MET R     1                                                      
REMARK 465     GLY R    64                                                      
REMARK 465     PRO R    65                                                      
REMARK 465     VAL R    66                                                      
REMARK 465     ARG R    67                                                      
REMARK 465     GLY R    68                                                      
REMARK 465     ILE R    69                                                      
REMARK 465     SER R    70                                                      
REMARK 465     PHE R    71                                                      
REMARK 465     LYS R    72                                                      
REMARK 465     ALA R    90                                                      
REMARK 465     LEU R    91                                                      
REMARK 465     ASP R    92                                                      
REMARK 465     LEU R    93                                                      
REMARK 465     SER R    94                                                      
REMARK 465     VAL R   127                                                      
REMARK 465     ARG R   128                                                      
REMARK 465     ASP R   129                                                      
REMARK 465     ARG R   130                                                      
REMARK 465     ARG R   131                                                      
REMARK 465     PHE R   132                                                      
REMARK 465     ARG R   133                                                      
REMARK 465     LYS R   134                                                      
REMARK 465     ARG R   135                                                      
REMARK 465     ASN R   136                                                      
REMARK 465     MET S     1                                                      
REMARK 465     MET T     1                                                      
REMARK 465     MET U     4                                                      
REMARK 465     SER U     5                                                      
REMARK 465     GLN U     6                                                      
REMARK 465     VAL U     7                                                      
REMARK 465     GLU U     8                                                      
REMARK 465     LYS U     9                                                      
REMARK 465     LYS U    10                                                      
REMARK 465     SER U    11                                                      
REMARK 465     GLU U    12                                                      
REMARK 465     GLN U    13                                                      
REMARK 465     GLN U    14                                                      
REMARK 465     MET W     1                                                      
REMARK 465     MET X     1                                                      
REMARK 465     MET Y     1                                                      
REMARK 465     MET Z     1                                                      
REMARK 465     PRO Z     2                                                      
REMARK 465     PRO Z     3                                                      
REMARK 465     LYS Z     4                                                      
REMARK 465     GLN Z     5                                                      
REMARK 465     GLN Z     6                                                      
REMARK 465     LEU Z     7                                                      
REMARK 465     SER Z     8                                                      
REMARK 465     LYS Z     9                                                      
REMARK 465     ALA Z    10                                                      
REMARK 465     ALA Z    11                                                      
REMARK 465     LYS Z    12                                                      
REMARK 465     ALA Z    13                                                      
REMARK 465     ALA Z    14                                                      
REMARK 465     ALA Z    15                                                      
REMARK 465     ALA Z    16                                                      
REMARK 465     MET Z    17                                                      
REMARK 465     ALA Z    18                                                      
REMARK 465     GLY Z    19                                                      
REMARK 465     GLY Z    20                                                      
REMARK 465     LYS Z    21                                                      
REMARK 465     LYS Z    22                                                      
REMARK 465     SER Z    23                                                      
REMARK 465     LYS Z    24                                                      
REMARK 465     LYS Z    25                                                      
REMARK 465     LYS Z    26                                                      
REMARK 465     TRP Z    27                                                      
REMARK 465     SER Z    28                                                      
REMARK 465     LYS Z    29                                                      
REMARK 465     LYS Z    30                                                      
REMARK 465     SER Z    31                                                      
REMARK 465     HIS Z    32                                                      
REMARK 465     LYS Z    33                                                      
REMARK 465     ASP Z    34                                                      
REMARK 465     LYS Z    35                                                      
REMARK 465     ALA Z   106                                                      
REMARK 465     SER Z   107                                                      
REMARK 465     GLU Z   108                                                      
REMARK 465     MET a     1                                                      
REMARK 465     ARG a   100                                                      
REMARK 465     PRO a   101                                                      
REMARK 465     ARG a   102                                                      
REMARK 465     PHE a   103                                                      
REMARK 465     ASN a   104                                                      
REMARK 465     ARG a   105                                                      
REMARK 465     ASP a   106                                                      
REMARK 465     ASN a   107                                                      
REMARK 465     LYS a   108                                                      
REMARK 465     VAL a   109                                                      
REMARK 465     SER a   110                                                      
REMARK 465     PRO a   111                                                      
REMARK 465     ALA a   112                                                      
REMARK 465     ASP a   113                                                      
REMARK 465     ALA a   114                                                      
REMARK 465     ALA a   115                                                      
REMARK 465     LYS a   116                                                      
REMARK 465     LYS a   117                                                      
REMARK 465     ALA a   118                                                      
REMARK 465     LEU a   119                                                      
REMARK 465     MET b     1                                                      
REMARK 465     MET c     1                                                      
REMARK 465     ASP c     2                                                      
REMARK 465     THR c     3                                                      
REMARK 465     LYS c     4                                                      
REMARK 465     THR c     5                                                      
REMARK 465     MET d     1                                                      
REMARK 465     ALA d     2                                                      
REMARK 465     HIS d     3                                                      
REMARK 465     MET e     1                                                      
REMARK 465     GLY e     2                                                      
REMARK 465     LYS e     3                                                      
REMARK 465     VAL e     4                                                      
REMARK 465     HIS e     5                                                      
REMARK 465     GLY e     6                                                      
REMARK 465     SER e     7                                                      
REMARK 465     SER e    62                                                      
REMARK 465     GLN e    63                                                      
REMARK 465     MET f     1                                                      
REMARK 465     GLN f     2                                                      
REMARK 465     ILE f     3                                                      
REMARK 465     PHE f     4                                                      
REMARK 465     VAL f     5                                                      
REMARK 465     LYS f     6                                                      
REMARK 465     THR f     7                                                      
REMARK 465     LEU f     8                                                      
REMARK 465     THR f     9                                                      
REMARK 465     GLY f    10                                                      
REMARK 465     LYS f    11                                                      
REMARK 465     THR f    12                                                      
REMARK 465     ILE f    13                                                      
REMARK 465     THR f    14                                                      
REMARK 465     LEU f    15                                                      
REMARK 465     GLU f    16                                                      
REMARK 465     VAL f    17                                                      
REMARK 465     GLU f    18                                                      
REMARK 465     SER f    19                                                      
REMARK 465     SER f    20                                                      
REMARK 465     ASP f    21                                                      
REMARK 465     THR f    22                                                      
REMARK 465     ILE f    23                                                      
REMARK 465     ASP f    24                                                      
REMARK 465     ASN f    25                                                      
REMARK 465     VAL f    26                                                      
REMARK 465     LYS f    27                                                      
REMARK 465     SER f    28                                                      
REMARK 465     LYS f    29                                                      
REMARK 465     ILE f    30                                                      
REMARK 465     GLN f    31                                                      
REMARK 465     ASP f    32                                                      
REMARK 465     LYS f    33                                                      
REMARK 465     GLU f    34                                                      
REMARK 465     GLY f    35                                                      
REMARK 465     ILE f    36                                                      
REMARK 465     PRO f    37                                                      
REMARK 465     PRO f    38                                                      
REMARK 465     ASP f    39                                                      
REMARK 465     GLN f    40                                                      
REMARK 465     GLN f    41                                                      
REMARK 465     ARG f    42                                                      
REMARK 465     LEU f    43                                                      
REMARK 465     ILE f    44                                                      
REMARK 465     PHE f    45                                                      
REMARK 465     ALA f    46                                                      
REMARK 465     GLY f    47                                                      
REMARK 465     LYS f    48                                                      
REMARK 465     GLN f    49                                                      
REMARK 465     LEU f    50                                                      
REMARK 465     GLU f    51                                                      
REMARK 465     ASP f    52                                                      
REMARK 465     GLY f    53                                                      
REMARK 465     ARG f    54                                                      
REMARK 465     THR f    55                                                      
REMARK 465     LEU f    56                                                      
REMARK 465     SER f    57                                                      
REMARK 465     ASP f    58                                                      
REMARK 465     TYR f    59                                                      
REMARK 465     ASN f    60                                                      
REMARK 465     ILE f    61                                                      
REMARK 465     GLN f    62                                                      
REMARK 465     LYS f    63                                                      
REMARK 465     GLU f    64                                                      
REMARK 465     SER f    65                                                      
REMARK 465     THR f    66                                                      
REMARK 465     LEU f    67                                                      
REMARK 465     HIS f    68                                                      
REMARK 465     LEU f    69                                                      
REMARK 465     VAL f    70                                                      
REMARK 465     LEU f    71                                                      
REMARK 465     ARG f    72                                                      
REMARK 465     LEU f    73                                                      
REMARK 465     ARG f    74                                                      
REMARK 465     GLY f    75                                                      
REMARK 465     GLY f    76                                                      
REMARK 465     GLY f    77                                                      
REMARK 465     LYS f    78                                                      
REMARK 465     LYS f    79                                                      
REMARK 465     ARG f    80                                                      
REMARK 465     LYS f    81                                                      
REMARK 465     MET g     1                                                      
REMARK 465     SER g     2                                                      
REMARK 465     GLU g   163                                                      
REMARK 465     ASP g   164                                                      
REMARK 465     GLY g   165                                                      
REMARK 465     GLU g   166                                                      
REMARK 465     GLU g   190                                                      
REMARK 465     ASP g   191                                                      
REMARK 465     MET i     1                                                      
REMARK 465     GLY i     2                                                      
REMARK 465     LYS i     3                                                      
REMARK 465     LYS i     4                                                      
REMARK 465     ASN i     5                                                      
REMARK 465     THR i     6                                                      
REMARK 465     LYS i     7                                                      
REMARK 465     GLY i     8                                                      
REMARK 465     GLY i     9                                                      
REMARK 465     LYS i    10                                                      
REMARK 465     LYS i    11                                                      
REMARK 465     GLY i    12                                                      
REMARK 465     ARG i    13                                                      
REMARK 465     ARG i    14                                                      
REMARK 465     GLY i    15                                                      
REMARK 465     LYS i    16                                                      
REMARK 465     ASN i    17                                                      
REMARK 465     ASP i    18                                                      
REMARK 465     SER i    19                                                      
REMARK 465     ASP i    20                                                      
REMARK 465     ASN i   116                                                      
REMARK 465     GLU i   117                                                      
REMARK 465     THR i   118                                                      
REMARK 465     ASP i   119                                                      
REMARK 465     ASN i   120                                                      
REMARK 465     PHE i   121                                                      
REMARK 465     GLY i   122                                                      
REMARK 465     PHE i   123                                                      
REMARK 465     GLU i   124                                                      
REMARK 465     SER i   125                                                      
REMARK 465     ASP i   126                                                      
REMARK 465     GLU i   127                                                      
REMARK 465     ASP i   128                                                      
REMARK 465     VAL i   129                                                      
REMARK 465     ASN i   130                                                      
REMARK 465     PHE i   131                                                      
REMARK 465     GLU i   132                                                      
REMARK 465     PHE i   133                                                      
REMARK 465     GLY i   134                                                      
REMARK 465     ASN i   135                                                      
REMARK 465     ALA i   136                                                      
REMARK 465     ASP i   137                                                      
REMARK 465     GLU i   138                                                      
REMARK 465     ASP i   139                                                      
REMARK 465     ASP i   140                                                      
REMARK 465     GLU i   141                                                      
REMARK 465     GLU i   142                                                      
REMARK 465     GLY i   143                                                      
REMARK 465     GLU i   144                                                      
REMARK 465     ASP i   145                                                      
REMARK 465     GLU i   146                                                      
REMARK 465     GLU i   147                                                      
REMARK 465     LEU i   148                                                      
REMARK 465     ASP i   149                                                      
REMARK 465     ILE i   150                                                      
REMARK 465     ASP i   151                                                      
REMARK 465     ASP i   152                                                      
REMARK 465     ILE i   153                                                      
REMARK 465     MET j     1                                                      
REMARK 465     SER j     2                                                      
REMARK 465     LYS j   175                                                      
REMARK 465     ARG j   176                                                      
REMARK 465     LEU j   177                                                      
REMARK 465     THR j   178                                                      
REMARK 465     PRO j   179                                                      
REMARK 465     GLN j   180                                                      
REMARK 465     ALA j   181                                                      
REMARK 465     MET j   211                                                      
REMARK 465     SER j   212                                                      
REMARK 465     THR j   213                                                      
REMARK 465     GLU j   214                                                      
REMARK 465     GLN j   215                                                      
REMARK 465     MET j   216                                                      
REMARK 465     GLN j   217                                                      
REMARK 465     MET j   266                                                      
REMARK 465     PRO j   267                                                      
REMARK 465     PRO j   268                                                      
REMARK 465     LYS j   269                                                      
REMARK 465     ALA j   270                                                      
REMARK 465     VAL j   271                                                      
REMARK 465     THR j   272                                                      
REMARK 465     ALA j   273                                                      
REMARK 465     THR j   274                                                      
REMARK 465     GLU j   275                                                      
REMARK 465     ASP j   276                                                      
REMARK 465     ALA j   277                                                      
REMARK 465     GLU j   278                                                      
REMARK 465     LEU j   279                                                      
REMARK 465     GLN j   280                                                      
REMARK 465     ALA j   281                                                      
REMARK 465     LEU j   282                                                      
REMARK 465     LEU j   283                                                      
REMARK 465     GLU j   284                                                      
REMARK 465     SER j   285                                                      
REMARK 465     LYS j   286                                                      
REMARK 465     GLU j   287                                                      
REMARK 465     LEU j   288                                                      
REMARK 465     ASP j   289                                                      
REMARK 465     ASN j   290                                                      
REMARK 465     ARG j   291                                                      
REMARK 465     SER j   292                                                      
REMARK 465     ASP j   293                                                      
REMARK 465     SER j   294                                                      
REMARK 465     GLU j   295                                                      
REMARK 465     ASP j   296                                                      
REMARK 465     ASP j   297                                                      
REMARK 465     GLU j   298                                                      
REMARK 465     ASP j   299                                                      
REMARK 465     GLU j   300                                                      
REMARK 465     SER j   301                                                      
REMARK 465     ASP j   302                                                      
REMARK 465     ASP j   303                                                      
REMARK 465     GLU j   304                                                      
REMARK 465     MET k     1                                                      
REMARK 465     SER k     2                                                      
REMARK 465     ASP k     3                                                      
REMARK 465     LEU k     4                                                      
REMARK 465     GLN k     5                                                      
REMARK 465     ASP k     6                                                      
REMARK 465     GLN k     7                                                      
REMARK 465     GLU k     8                                                      
REMARK 465     PRO k     9                                                      
REMARK 465     SER k    10                                                      
REMARK 465     ILE k    11                                                      
REMARK 465     ILE k    12                                                      
REMARK 465     ILE k    13                                                      
REMARK 465     ASN k    14                                                      
REMARK 465     GLY k    15                                                      
REMARK 465     ASN k    16                                                      
REMARK 465     LEU k    17                                                      
REMARK 465     GLU k    18                                                      
REMARK 465     PRO k    19                                                      
REMARK 465     VAL k    20                                                      
REMARK 465     GLY k    21                                                      
REMARK 465     GLU k    22                                                      
REMARK 465     PRO k    23                                                      
REMARK 465     ASP k    24                                                      
REMARK 465     ILE k    25                                                      
REMARK 465     VAL k    26                                                      
REMARK 465     GLU k    27                                                      
REMARK 465     GLU k    28                                                      
REMARK 465     THR k    29                                                      
REMARK 465     GLU k    30                                                      
REMARK 465     VAL k    31                                                      
REMARK 465     VAL k    32                                                      
REMARK 465     ALA k    33                                                      
REMARK 465     GLN k    34                                                      
REMARK 465     GLU k    35                                                      
REMARK 465     THR k    36                                                      
REMARK 465     GLN k    37                                                      
REMARK 465     GLU k    38                                                      
REMARK 465     THR k    39                                                      
REMARK 465     GLN k    40                                                      
REMARK 465     ASP k    41                                                      
REMARK 465     ALA k    42                                                      
REMARK 465     ASP k    43                                                      
REMARK 465     LYS k    44                                                      
REMARK 465     PRO k    45                                                      
REMARK 465     LYS k    46                                                      
REMARK 465     LYS k    47                                                      
REMARK 465     LYS k    48                                                      
REMARK 465     VAL k    49                                                      
REMARK 465     ALA k    50                                                      
REMARK 465     PHE k    51                                                      
REMARK 465     THR k    52                                                      
REMARK 465     GLY k    53                                                      
REMARK 465     LEU k    54                                                      
REMARK 465     GLU k    55                                                      
REMARK 465     GLU k    56                                                      
REMARK 465     ASP k    57                                                      
REMARK 465     GLY k    58                                                      
REMARK 465     GLU k    59                                                      
REMARK 465     THR k    60                                                      
REMARK 465     GLU k    61                                                      
REMARK 465     GLU k    62                                                      
REMARK 465     GLU k    63                                                      
REMARK 465     LYS k    64                                                      
REMARK 465     ARG k    65                                                      
REMARK 465     LYS k    66                                                      
REMARK 465     ARG k    67                                                      
REMARK 465     GLU k    68                                                      
REMARK 465     PHE k    69                                                      
REMARK 465     GLU k    70                                                      
REMARK 465     GLU k    71                                                      
REMARK 465     GLY k    72                                                      
REMARK 465     GLY k    73                                                      
REMARK 465     GLY k    74                                                      
REMARK 465     LEU k    75                                                      
REMARK 465     PRO k    76                                                      
REMARK 465     GLU k    77                                                      
REMARK 465     GLN k    78                                                      
REMARK 465     PRO k    79                                                      
REMARK 465     LEU k    80                                                      
REMARK 465     ASN k    81                                                      
REMARK 465     PRO k    82                                                      
REMARK 465     ASP k    83                                                      
REMARK 465     PHE k    84                                                      
REMARK 465     SER k    85                                                      
REMARK 465     LYS k    86                                                      
REMARK 465     LEU k    87                                                      
REMARK 465     ASN k    88                                                      
REMARK 465     PRO k    89                                                      
REMARK 465     LEU k    90                                                      
REMARK 465     SER k    91                                                      
REMARK 465     ALA k    92                                                      
REMARK 465     GLU k    93                                                      
REMARK 465     ILE k    94                                                      
REMARK 465     ILE k    95                                                      
REMARK 465     ASN k    96                                                      
REMARK 465     ARG k    97                                                      
REMARK 465     PRO k   153                                                      
REMARK 465     THR k   154                                                      
REMARK 465     CYS k   155                                                      
REMARK 465     PRO k   156                                                      
REMARK 465     GLU k   157                                                      
REMARK 465     PRO k   158                                                      
REMARK 465     ASP k   159                                                      
REMARK 465     CYS k   160                                                      
REMARK 465     TYR k   161                                                      
REMARK 465     ARG k   162                                                      
REMARK 465     SER k   163                                                      
REMARK 465     PHE k   164                                                      
REMARK 465     LYS k   165                                                      
REMARK 465     SER k   166                                                      
REMARK 465     ASP k   167                                                      
REMARK 465     LYS k   168                                                      
REMARK 465     LYS k   362                                                      
REMARK 465     ASP k   363                                                      
REMARK 465     ASP k   364                                                      
REMARK 465     LYS k   365                                                      
REMARK 465     GLY k   366                                                      
REMARK 465     LYS k   367                                                      
REMARK 465     THR k   445                                                      
REMARK 465     ASP k   446                                                      
REMARK 465     GLY k   447                                                      
REMARK 465     GLN k   448                                                      
REMARK 465     GLY k   520                                                      
REMARK 465     THR k   521                                                      
REMARK 465     THR k   522                                                      
REMARK 465     LEU k   523                                                      
REMARK 465     GLU k   524                                                      
REMARK 465     PRO k   525                                                      
REMARK 465     ILE k   526                                                      
REMARK 465     ALA k   527                                                      
REMARK 465     MET l     1                                                      
REMARK 465     SER l     2                                                      
REMARK 465     SER l     3                                                      
REMARK 465     ASP l     4                                                      
REMARK 465     LEU l     5                                                      
REMARK 465     ALA l     6                                                      
REMARK 465     ALA l     7                                                      
REMARK 465     GLU l     8                                                      
REMARK 465     LEU l     9                                                      
REMARK 465     GLY l    10                                                      
REMARK 465     PHE l    11                                                      
REMARK 465     ASP l    12                                                      
REMARK 465     PRO l    13                                                      
REMARK 465     ALA l    14                                                      
REMARK 465     LEU l    15                                                      
REMARK 465     LYS l    16                                                      
REMARK 465     LYS l    17                                                      
REMARK 465     LYS l    18                                                      
REMARK 465     LYS l    19                                                      
REMARK 465     LYS l    20                                                      
REMARK 465     THR l    21                                                      
REMARK 465     LYS l    22                                                      
REMARK 465     LYS l    23                                                      
REMARK 465     VAL l    24                                                      
REMARK 465     ILE l    25                                                      
REMARK 465     PRO l    26                                                      
REMARK 465     ASP l    27                                                      
REMARK 465     ASP l    28                                                      
REMARK 465     PHE l    29                                                      
REMARK 465     ASP l    30                                                      
REMARK 465     ALA l    31                                                      
REMARK 465     ALA l    32                                                      
REMARK 465     VAL l    33                                                      
REMARK 465     ASN l    34                                                      
REMARK 465     GLY l    35                                                      
REMARK 465     LYS l    36                                                      
REMARK 465     GLU l    37                                                      
REMARK 465     ASN l    38                                                      
REMARK 465     GLY l    39                                                      
REMARK 465     SER l    40                                                      
REMARK 465     GLY l    41                                                      
REMARK 465     ASP l    42                                                      
REMARK 465     ASP l    43                                                      
REMARK 465     LEU l    44                                                      
REMARK 465     PHE l    45                                                      
REMARK 465     ALA l    46                                                      
REMARK 465     GLY l    47                                                      
REMARK 465     LEU l    48                                                      
REMARK 465     LYS l    49                                                      
REMARK 465     LYS l    50                                                      
REMARK 465     LYS l    51                                                      
REMARK 465     LYS l    52                                                      
REMARK 465     LYS l    53                                                      
REMARK 465     LYS l    54                                                      
REMARK 465     SER l    55                                                      
REMARK 465     LYS l    56                                                      
REMARK 465     SER l    57                                                      
REMARK 465     VAL l    58                                                      
REMARK 465     SER l    59                                                      
REMARK 465     ALA l    60                                                      
REMARK 465     ASP l    61                                                      
REMARK 465     ALA l    62                                                      
REMARK 465     GLU l    63                                                      
REMARK 465     ALA l    64                                                      
REMARK 465     GLU l    65                                                      
REMARK 465     LYS l    66                                                      
REMARK 465     GLU l    67                                                      
REMARK 465     PRO l    68                                                      
REMARK 465     THR l    69                                                      
REMARK 465     ASP l    70                                                      
REMARK 465     ASP l    71                                                      
REMARK 465     ILE l    72                                                      
REMARK 465     ALA l    73                                                      
REMARK 465     GLU l    74                                                      
REMARK 465     ALA l    75                                                      
REMARK 465     LEU l    76                                                      
REMARK 465     GLY l    77                                                      
REMARK 465     GLU l    78                                                      
REMARK 465     LEU l    79                                                      
REMARK 465     SER l    80                                                      
REMARK 465     LEU l    81                                                      
REMARK 465     LYS l    82                                                      
REMARK 465     LYS l    83                                                      
REMARK 465     LYS l    84                                                      
REMARK 465     LYS l    85                                                      
REMARK 465     LYS l    86                                                      
REMARK 465     LYS l    87                                                      
REMARK 465     THR l    88                                                      
REMARK 465     LYS l    89                                                      
REMARK 465     ASP l    90                                                      
REMARK 465     SER l    91                                                      
REMARK 465     SER l    92                                                      
REMARK 465     VAL l    93                                                      
REMARK 465     ASP l    94                                                      
REMARK 465     ALA l    95                                                      
REMARK 465     PHE l    96                                                      
REMARK 465     GLU l    97                                                      
REMARK 465     LYS l    98                                                      
REMARK 465     GLU l    99                                                      
REMARK 465     LEU l   100                                                      
REMARK 465     ALA l   101                                                      
REMARK 465     LYS l   102                                                      
REMARK 465     ALA l   103                                                      
REMARK 465     GLY l   104                                                      
REMARK 465     LEU l   105                                                      
REMARK 465     ASP l   106                                                      
REMARK 465     ASN l   107                                                      
REMARK 465     VAL l   108                                                      
REMARK 465     ASP l   109                                                      
REMARK 465     ALA l   110                                                      
REMARK 465     GLU l   111                                                      
REMARK 465     SER l   112                                                      
REMARK 465     LYS l   113                                                      
REMARK 465     GLU l   114                                                      
REMARK 465     GLY l   115                                                      
REMARK 465     THR l   116                                                      
REMARK 465     PRO l   117                                                      
REMARK 465     SER l   118                                                      
REMARK 465     ALA l   119                                                      
REMARK 465     ASN l   120                                                      
REMARK 465     SER l   121                                                      
REMARK 465     SER l   122                                                      
REMARK 465     ILE l   123                                                      
REMARK 465     GLN l   124                                                      
REMARK 465     GLN l   125                                                      
REMARK 465     GLU l   126                                                      
REMARK 465     THR l   144                                                      
REMARK 465     ASN l   145                                                      
REMARK 465     ASN l   146                                                      
REMARK 465     PRO l   147                                                      
REMARK 465     GLU l   148                                                      
REMARK 465     LEU l   149                                                      
REMARK 465     ALA l   150                                                      
REMARK 465     GLY l   151                                                      
REMARK 465     ASP l   152                                                      
REMARK 465     ARG l   153                                                      
REMARK 465     SER l   154                                                      
REMARK 465     GLY l   155                                                      
REMARK 465     PRO l   156                                                      
REMARK 465     GLN l   208                                                      
REMARK 465     GLN l   250                                                      
REMARK 465     SER l   251                                                      
REMARK 465     ILE l   271                                                      
REMARK 465     LYS l   272                                                      
REMARK 465     THR l   273                                                      
REMARK 465     GLY l   274                                                      
REMARK 465     PHE l   275                                                      
REMARK 465     GLN l   276                                                      
REMARK 465     ALA l   277                                                      
REMARK 465     THR l   278                                                      
REMARK 465     VAL l   279                                                      
REMARK 465     GLY l   280                                                      
REMARK 465     LYS l   281                                                      
REMARK 465     ARG l   282                                                      
REMARK 465     ARG l   283                                                      
REMARK 465     ARG l   284                                                      
REMARK 465     MET l   285                                                      
REMARK 465     MET m     1                                                      
REMARK 465     SER m     2                                                      
REMARK 465     ILE m     3                                                      
REMARK 465     GLU m     4                                                      
REMARK 465     ASN m     5                                                      
REMARK 465     LEU m     6                                                      
REMARK 465     LYS m     7                                                      
REMARK 465     SER m     8                                                      
REMARK 465     PHE m     9                                                      
REMARK 465     ASP m    10                                                      
REMARK 465     PRO m    11                                                      
REMARK 465     PHE m    12                                                      
REMARK 465     ALA m    13                                                      
REMARK 465     ASP m    14                                                      
REMARK 465     THR m    15                                                      
REMARK 465     GLY m    16                                                      
REMARK 465     ASP m    17                                                      
REMARK 465     ASP m    18                                                      
REMARK 465     GLU m    19                                                      
REMARK 465     THR m    20                                                      
REMARK 465     ALA m    21                                                      
REMARK 465     THR m    22                                                      
REMARK 465     MET q   343                                                      
REMARK 465     GLN q   344                                                      
REMARK 465     GLU q   345                                                      
REMARK 465     ALA q   346                                                      
REMARK 465     ASN q   347                                                      
REMARK 470                                                                      
REMARK 470 MISSING ATOM                                                         
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;           
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;          
REMARK 470 I=INSERTION CODE):                                                   
REMARK 470   M RES CSSEQI  ATOMS                                                
REMARK 470       A 21692    N9   C8   N7   C5   C6   N6   N1                    
REMARK 470       A 21692    C2   N3   C4                                        
REMARK 470       G 21693    N9   C8   N7   C5   C6   O6   N1                    
REMARK 470       G 21693    C2   N2   N3   C4                                   
REMARK 470       G 21694    N9   C8   N7   C5   C6   O6   N1                    
REMARK 470       G 21694    C2   N2   N3   C4                                   
REMARK 470       G 21695    N9   C8   N7   C5   C6   O6   N1                    
REMARK 470       G 21695    C2   N2   N3   C4                                   
REMARK 470       G 21696    N9   C8   N7   C5   C6   O6   N1                    
REMARK 470       G 21696    C2   N2   N3   C4                                   
REMARK 470       G 21697    N9   C8   N7   C5   C6   O6   N1                    
REMARK 470       G 21697    C2   N2   N3   C4                                   
REMARK 470       C 21698    N1   C2   O2   N3   C4   N4   C5                    
REMARK 470       C 21698    C6                                                  
REMARK 470       A 21699    N9   C8   N7   C5   C6   N6   N1                    
REMARK 470       A 21699    C2   N3   C4                                        
REMARK 470       A 21700    N9   C8   N7   C5   C6   N6   N1                    
REMARK 470       A 21700    C2   N3   C4                                        
REMARK 470       C 21701    N1   C2   O2   N3   C4   N4   C5                    
REMARK 470       C 21701    C6                                                  
REMARK 470       U 21702    N1   C2   O2   N3   C4   O4   C5                    
REMARK 470       U 21702    C6                                                  
REMARK 470       C 21703    N1   C2   O2   N3   C4   N4   C5                    
REMARK 470       C 21703    C6                                                  
REMARK 470       C 21704    N1   C2   O2   N3   C4   N4   C5                    
REMARK 470       C 21704    C6                                                  
REMARK 470       A 21705    N9   C8   N7   C5   C6   N6   N1                    
REMARK 470       A 21705    C2   N3   C4                                        
REMARK 470     LYS A  27    CG   CD   CE   NZ                                   
REMARK 470     GLU A 209    CG   CD   OE1  OE2                                  
REMARK 470     LYS B   5    CG   CD   CE   NZ                                   
REMARK 470     ASN B   6    CG   OD1  ND2                                       
REMARK 470     LYS B   7    CG   CD   CE   NZ                                   
REMARK 470     LEU B   9    CG   CD1  CD2                                       
REMARK 470     ARG B  19    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS I 123    CG   CD   CE   NZ                                   
REMARK 470     LEU e   8    CG   CD1  CD2                                       
REMARK 470     GLN f 149    CG   CD   OE1  NE2                                  
REMARK 470     LYS f 150    CG   CD   CE   NZ                                   
REMARK 470     TYR k 183    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT                     
REMARK 500                                                                      
REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT.                            
REMARK 500                                                                      
REMARK 500  ATM1  RES C  SSEQI   ATM2  RES C  SSEQI           DISTANCE          
REMARK 500   OP1    C 2   404    MG     MG 2  1843              1.36            
REMARK 500   OP2    G 2  1427    MG     MG 2  1875              1.61            
REMARK 500   OP2    G 2  1010    MG     MG 2  1853              1.64            
REMARK 500   OP2    G 2  1539    MG     MG 2  1866              1.67            
REMARK 500   OP1    A 2   549    MG     MG 2  1839              1.69            
REMARK 500   OP2  H2U 1    16     C2     A 1    60              2.19            
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: COVALENT BOND LENGTHS                                      
REMARK 500                                                                      
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES              
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE               
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                 
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT: (10X,I3,1X,2(A3,1X,A1,I4,A1,1X,A4,3X),1X,F6.3)               
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999                        
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996                     
REMARK 500                                                                      
REMARK 500  M RES CSSEQI ATM1   RES CSSEQI ATM2   DEVIATION                     
REMARK 500      A 1   1   P       A 1   1   OP3    -0.120                       
REMARK 500      G 1  65   P       G 1  65   O5'    -0.067                       
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES                                       
REMARK 500                                                                      
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES              
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE               
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                 
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)              
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999                        
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996                     
REMARK 500                                                                      
REMARK 500  M RES CSSEQI ATM1   ATM2   ATM3                                     
REMARK 500    RIA 1  64   O3' -  P   -  O5' ANGL. DEV. = -11.9 DEGREES          
REMARK 500      G 1  65   OP1 -  P   -  OP2 ANGL. DEV. = -12.6 DEGREES          
REMARK 500      G 1  65   O5' -  P   -  OP1 ANGL. DEV. =   7.4 DEGREES          
REMARK 500      G 1  65   O5' -  P   -  OP2 ANGL. DEV. =   7.6 DEGREES          
REMARK 500      G 1  65   O5' -  C5' -  C4' ANGL. DEV. =  -8.2 DEGREES          
REMARK 500      A 2 685   C2' -  C3' -  O3' ANGL. DEV. =  11.1 DEGREES          
REMARK 500    LEU I  29   CA  -  CB  -  CG  ANGL. DEV. =  15.5 DEGREES          
REMARK 500    PRO f 126   CA  -  N   -  CD  ANGL. DEV. = -12.6 DEGREES          
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: TORSION ANGLES                                             
REMARK 500                                                                      
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:            
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)                    
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-           
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400            
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        PSI       PHI                                   
REMARK 500    ARG A  21       63.76     62.13                                   
REMARK 500    LYS A  27      176.99     63.14                                   
REMARK 500    LYS A  39      145.09     64.17                                   
REMARK 500    ALA A  95      167.90     61.79                                   
REMARK 500    THR A 103      119.04     70.10                                   
REMARK 500    ASN A 109      110.37     65.37                                   
REMARK 500    SER A 114       30.02    -99.16                                   
REMARK 500    ASP A 150      -41.67   -156.32                                   
REMARK 500    SER A 153       52.07    -93.69                                   
REMARK 500    TYR A 155       10.09     58.64                                   
REMARK 500    VAL A 158       92.16     61.87                                   
REMARK 500    LYS A 167      -54.96     66.96                                   
REMARK 500    TRP A 195      147.18     69.33                                   
REMARK 500    TYR A 202     -100.63    -72.87                                   
REMARK 500    PHE A 203     -146.08     49.40                                   
REMARK 500    PRO A 207       94.94    -50.71                                   
REMARK 500    GLU A 208      -41.82   -133.68                                   
REMARK 500    ARG B   8       96.40     58.25                                   
REMARK 500    ASP B  22       98.04     62.76                                   
REMARK 500    LEU B  54      138.34     68.72                                   
REMARK 500    LYS B  55       80.75     62.73                                   
REMARK 500    ASP B  89      -46.84   -131.31                                   
REMARK 500    LYS B  94       -9.88     63.61                                   
REMARK 500    TRP B 117      -38.87     69.25                                   
REMARK 500    ASP B 131     -124.55    -80.90                                   
REMARK 500    ALA B 147       48.36    -77.38                                   
REMARK 500    ASN B 148      -15.29   -161.06                                   
REMARK 500    SER B 154       87.50     55.64                                   
REMARK 500    GLN B 177      -36.70     85.81                                   
REMARK 500    SER B 179      173.95     63.62                                   
REMARK 500    PRO B 190       42.70    -92.85                                   
REMARK 500    GLU B 191       47.76     38.11                                   
REMARK 500    LEU B 207      144.66     64.02                                   
REMARK 500    LYS B 214       93.47     62.87                                   
REMARK 500    PRO B 221      -79.73    -65.14                                   
REMARK 500    LYS B 222     -111.31   -132.96                                   
REMARK 500    PHE B 223      -59.23   -129.65                                   
REMARK 500    ASP B 224       88.99     52.41                                   
REMARK 500    THR C  44      154.59     68.03                                   
REMARK 500    ARG C  96      -94.33     52.49                                   
REMARK 500    ASP C 111     -115.33    -80.58                                   
REMARK 500    SER C 112       -3.38   -155.16                                   
REMARK 500    ASN C 113       32.99    -96.80                                   
REMARK 500    THR C 151      120.02     66.74                                   
REMARK 500    GLN C 155      110.49     61.29                                   
REMARK 500    PRO C 156      104.07    -58.25                                   
REMARK 500    SER C 158     -158.83   -114.36                                   
REMARK 500    VAL C 184       78.90   -108.34                                   
REMARK 500    GLN C 238     -118.08    -91.49                                   
REMARK 500    LEU C 240       89.28     59.10                                   
REMARK 500                                                                      
REMARK 500 THIS ENTRY HAS     527 RAMACHANDRAN OUTLIERS.                        
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: NON-CIS, NON-TRANS                                         
REMARK 500                                                                      
REMARK 500 THE FOLLOWING PEPTIDE BONDS DEVIATE SIGNIFICANTLY FROM BOTH          
REMARK 500 CIS AND TRANS CONFORMATION.  CIS BONDS, IF ANY, ARE LISTED           
REMARK 500 ON CISPEP RECORDS.  TRANS IS DEFINED AS 180 +/- 30 AND               
REMARK 500 CIS IS DEFINED AS 0 +/- 30 DEGREES.                                  
REMARK 500                                 MODEL     OMEGA                      
REMARK 500 GLN X   63     PRO X   64                 -138.27                    
REMARK 500 HIS Y   29     PRO Y   30                 -149.63                    
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 610                                                                      
REMARK 610 MISSING HETEROATOM                                                   
REMARK 610 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;           
REMARK 610 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;          
REMARK 610 I=INSERTION CODE):                                                   
REMARK 610   M RES C SSEQI                                                      
REMARK 610     MET k  601                                                       
REMARK 620                                                                      
REMARK 620 METAL COORDINATION                                                   
REMARK 620 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 620 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE):                             
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21824  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   A 2 618   OP2                                                    
REMARK 620 2   A 2 618   OP1  80.0                                              
REMARK 620 3   A 2 619   OP1 108.4  80.8                                        
REMARK 620 4   A 2 619   OP2  80.0 121.0  54.8                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21878  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   G 21427   OP2                                                    
REMARK 620 2   G 21427   O5'  72.0                                              
REMARK 620 3   G 21427   OP1  70.5  61.5                                        
REMARK 620 N                    1     2                                         
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21835  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   A 2 459   OP2                                                    
REMARK 620 2   G 2 458   O3'  67.9                                              
REMARK 620 3   G 2 460   OP2  76.3 115.2                                        
REMARK 620 N                    1     2                                         
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21815  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   A 2 377   OP2                                                    
REMARK 620 2   U 2 378   OP2  83.4                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21809  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   G 2 573   OP1                                                    
REMARK 620 2   C 2 572   O3'  70.9                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21871  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   C 21176   OP1                                                    
REMARK 620 2   C 21176   OP2  79.0                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21832  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   G 21791   OP2                                                    
REMARK 620 2   G 21791   OP1  81.3                                              
REMARK 620 3   G 21790   O3'  70.6  70.4                                        
REMARK 620 4   U 21628   OP1 122.5  78.7 144.2                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21830  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   G 2  95   OP2                                                    
REMARK 620 2   U 2  94   OP1 108.0                                              
REMARK 620 3   U 2  94   OP2 148.0  75.7                                        
REMARK 620 4   U 2  94   O5'  98.3  57.9  55.8                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG k 602  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 GCP k 603   O1G                                                    
REMARK 620 2 THR k 137   OG1  88.7                                              
REMARK 620 3 ASP k 193   OD2 125.9 136.6                                        
REMARK 620 N                    1     2                                         
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21837  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   A 2 622   OP2                                                    
REMARK 620 2   A 2 621   O3'  68.9                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21825  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   A 2 622   OP2                                                    
REMARK 620 2   A 2 622   OP1  74.8                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21876  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   G 21537   OP2                                                    
REMARK 620 2   G 21539   O6   91.2                                              
REMARK 620 3   G 21537   O5'  70.7 131.3                                        
REMARK 620 N                    1     2                                         
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21811  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   A 21761   OP1                                                    
REMARK 620 2   G 21766   OP1  96.3                                              
REMARK 620 3   U 21769   OP1 102.1 156.6                                        
REMARK 620 4   G 21765   O3'  97.8  67.2  95.8                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21803  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   A 2 555   OP2                                                    
REMARK 620 2   A 2 555   O5'  69.7                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21807  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   C 2  49   OP2                                                    
REMARK 620 2   C 2  49   O5'  55.8                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21820  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   U 2  44   OP1                                                    
REMARK 620 2   A 2  47   OP2  88.9                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21804  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   A 2 100   OP1                                                    
REMARK 620 2   A 2 100   OP2  63.5                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21833  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   U 2 169   OP1                                                    
REMARK 620 2   U 2  64   OP1 129.4                                              
REMARK 620 3   G 2  63   O3' 123.4  69.6                                        
REMARK 620 4   C 2 267   O5'  92.0 106.1 138.6                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21821  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   A 21760   OP2                                                    
REMARK 620 2   G 21766   OP2 122.9                                              
REMARK 620 3   U 21759   O3'  57.8 161.9                                        
REMARK 620 N                    1     2                                         
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21847  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   A 2 760   OP2                                                    
REMARK 620 2   U 2 759   O5'  91.9                                              
REMARK 620 3   U 2 759   OP2 147.8  58.7                                        
REMARK 620 N                    1     2                                         
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21826  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   U 2 101   OP2                                                    
REMARK 620 2   A 2 100   OP2  83.0                                              
REMARK 620 3   U 2 102   O4  138.2 132.4                                        
REMARK 620 N                    1     2                                         
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21864  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   G 21327   OP2                                                    
REMARK 620 2   A 21328   OP2 142.5                                              
REMARK 620 3   G 21327   O5'  67.3  80.7                                        
REMARK 620 4   G 21327   OP1  62.3 115.3  56.3                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21810  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   A 2 928   OP2                                                    
REMARK 620 2   U 2 927   O2' 107.9                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21873  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   G 21270   O6                                                     
REMARK 620 2   U 21271   O4  106.1                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21828  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   G 21106   O3'                                                    
REMARK 620 2   G 21107   OP1  69.1                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21860  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   U 21116   O4                                                     
REMARK 620 2   U 2 312   O4   74.3                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              ZN a 500  ZN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS a  74   SG                                                     
REMARK 620 2 CYS a  23   SG  101.6                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21841  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   G 21046   OP1                                                    
REMARK 620 2   U 2 872   O2' 101.0                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21862  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   U 2 885   O4                                                     
REMARK 620 2   G 2 924   O6  150.1                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21817  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   G 2 606   OP1                                                    
REMARK 620 2   G 2 606   OP2  66.1                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              ZN b 101  ZN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS b  40   SG                                                     
REMARK 620 2 CYS b  37   SG  113.8                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              ZN f 501  ZN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS f 139   SG                                                     
REMARK 620 2 CYS f 124   SG  128.0                                              
REMARK 620 3 CYS f 142   N   106.1 123.7                                        
REMARK 620 N                    1     2                                         
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21840  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   C 2 353   OP2                                                    
REMARK 620 2   C 2 353   O5'  62.5                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21813  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   C 2 401   O2                                                     
REMARK 620 2   A 2 400   OP2 159.0                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21839  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   A 2 549   OP2                                                    
REMARK 620 2   U 2 581   O3' 116.9                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21858  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   G 2 383   O6                                                     
REMARK 620 2   U 2  98   O4   94.5                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21814  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   U 2 607   OP2                                                    
REMARK 620 2   U 2 607   O4'  97.5                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21875  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   C 21273   OP2                                                    
REMARK 620 2   G 21426   OP2  72.7                                              
REMARK 620 3   C 21273   OP1  58.0 109.5                                        
REMARK 620 4   G 21426   OP1  84.5  54.4  72.8                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 21843  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   C 2 404   OP2                                                    
REMARK 620 2   G 2 403   O3'  52.5                                              
REMARK 620 N                    1                                               
REMARK 800                                                                      
REMARK 800 SITE                                                                 
REMARK 800 SITE_IDENTIFIER: AC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1801                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1802                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC3                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1803                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC4                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1804                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC5                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1805                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC6                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1806                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC7                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1807                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC8                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1808                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC9                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1809                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: BC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1810                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: BC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1811                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: BC3                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1812                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: BC4                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1813                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: BC5                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1814                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: BC6                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1815                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: BC7                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1816                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: BC8                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1817                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: BC9                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1818                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: CC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1819                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: CC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1820                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: CC3                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1821                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: CC4                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1822                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: CC5                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1823                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: CC6                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1824                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: CC7                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1825                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: CC8                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1826                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: CC9                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1827                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: DC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1828                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: DC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1829                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: DC3                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1830                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: DC4                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1831                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: DC5                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1832                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: DC6                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1833                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: DC7                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1834                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: DC8                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1835                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: DC9                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1836                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: EC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1837                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: EC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1838                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: EC3                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1839                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: EC4                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1840                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: EC5                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1841                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: EC6                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1842                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: EC7                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1843                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: EC8                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1844                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: EC9                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1845                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: FC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1846                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: FC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1847                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: FC3                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1848                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: FC4                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1849                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: FC5                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1850                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: FC6                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1851                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: FC7                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1853                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: FC8                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1854                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: FC9                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1855                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: GC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1856                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: GC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1857                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: GC3                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1858                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: GC4                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1859                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: GC5                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1860                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: GC6                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1861                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: GC7                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1862                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: GC8                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1863                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: GC9                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1864                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: HC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1865                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: HC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1866                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: HC3                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1867                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: HC4                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1868                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: HC5                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1869                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: HC6                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1870                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: HC7                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1871                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: HC8                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1872                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: HC9                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1873                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: IC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1874                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: IC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1875                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: IC3                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1876                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: IC4                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1878                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: IC5                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1879                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: IC6                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG C 301                  
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: IC7                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG Q 201                  
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: IC8                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN a 500                  
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: IC9                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN b 101                  
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: JC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN f 501                  
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: JC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MET k 601                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: JC3                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG k 602                  
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: JC4                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE GCP k 603                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: JC5                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN l 301                  
REMARK 900                                                                      
REMARK 900 RELATED ENTRIES                                                      
REMARK 900 RELATED ID: EMD-3049   RELATED DB: EMDB                              
REMARK 900 RELATED ID: EMD-3047   RELATED DB: EMDB                              
REMARK 900 RELATED ID: EMD-3048   RELATED DB: EMDB                              
REMARK 900 RELATED ID: 3JAM   RELATED DB: PDB                                   
REMARK 900 RELATED ID: 3JAP   RELATED DB: PDB                                   
DBREF  3JAQ A    1   254  UNP    Q6CN12   RSSA_KLULA       1    254             
DBREF  3JAQ B    1   255  UNP    Q6CWD0   RS3A_KLULA       1    255             
DBREF  3JAQ C    1   259  UNP    Q6CKL3   Q6CKL3_KLULA     1    259             
DBREF  3JAQ D    1   237  UNP    Q6CRK7   Q6CRK7_KLULA     1    237             
DBREF  3JAQ E    1   261  UNP    Q6CWJ2   Q6CWJ2_KLULA     1    261             
DBREF  3JAQ F    1   227  UNP    Q6CRA3   Q6CRA3_KLULA     1    227             
DBREF  3JAQ G    1   236  UNP    Q6CM04   RS6_KLULA        1    236             
DBREF  3JAQ H    1   190  UNP    Q6CTD6   Q6CTD6_KLULA     1    190             
DBREF  3JAQ I    1   201  UNP    Q6CMG3   Q6CMG3_KLULA     1    201             
DBREF  3JAQ J    1   188  UNP    Q6CM18   Q6CM18_KLULA     1    188             
DBREF  3JAQ K    1   106  UNP    Q6CVZ5   Q6CVZ5_KLULA     1    106             
DBREF  3JAQ L    1   156  UNP    Q6CX80   Q6CX80_KLULA     1    156             
DBREF  3JAQ M    1   134  UNP    Q6CLU4   Q6CLU4_KLULA     1    134             
DBREF  3JAQ N    1   151  UNP    Q6CJK0   Q6CJK0_KLULA     1    151             
DBREF  3JAQ O    1   137  UNP    P27069   RS14_KLULA       1    137             
DBREF  3JAQ P    1   142  UNP    Q6CKV4   Q6CKV4_KLULA     1    142             
DBREF  3JAQ Q    1   143  UNP    Q875N2   RS16_KLULA       1    143             
DBREF  3JAQ R    1   136  UNP    Q6CWU3   Q6CWU3_KLULA     1    136             
DBREF  3JAQ S    1   146  UNP    Q6CWT9   Q6CWT9_KLULA     1    146             
DBREF  3JAQ T    1   144  UNP    Q6CXM0   Q6CXM0_KLULA     1    144             
DBREF  3JAQ U    4   120  UNP    Q6CIM1   Q6CIM1_KLULA     1    117             
DBREF  3JAQ V    1    87  UNP    Q6CXT6   RS21_KLULA       1     87             
DBREF  3JAQ W    1   130  UNP    Q6CW21   RS22_KLULA       1    130             
DBREF  3JAQ X    1   145  UNP    F2Z602   F2Z602_KLULA     1    145             
DBREF  3JAQ Y    1   135  UNP    Q6CU44   Q6CU44_KLULA     1    135             
DBREF  3JAQ Z    1   108  UNP    Q6CW78   Q6CW78_KLULA     1    108             
DBREF  3JAQ a    1   119  UNP    Q6CS01   Q6CS01_KLULA     1    119             
DBREF  3JAQ b    1    82  UNP    Q6CNL2   Q6CNL2_KLULA     1     82             
DBREF  3JAQ c    1    67  UNP    P33285   RS28_KLULA       1     67             
DBREF  3JAQ d    1    56  UNP    Q6CPG3   RS29_KLULA       1     56             
DBREF  3JAQ e    1    63  UNP    Q6CUH5   Q6CUH5_KLULA     1     63             
DBREF  3JAQ f    1   150  UNP    P69061   RS27A_KLULA      1    150             
DBREF  3JAQ g    1   326  UNP    Q6CNI7   Q6CNI7_KLULA     1    326             
DBREF  3JAQ h    1    25  UNP    P0CX86   RL41A_YEAST      1     25             
DBREF  3JAQ i    1   153  UNP    P38912   IF1A_YEAST       1    153             
DBREF  3JAQ j    1   304  UNP    P20459   IF2A_YEAST       1    304             
DBREF  3JAQ k    1   527  UNP    P32481   IF2G_YEAST       1    527             
DBREF  3JAQ l    1   285  UNP    P09064   IF2B_YEAST       1    285             
DBREF  3JAQ m    1   108  UNP    P32911   SUI1_YEAST       1    108             
DBREF  3JAQ q    1   347  UNP    P40217   EIF3I_YEAST      1    347             
DBREF  3JAQ r  704   737  UNP    P06103   EIF3B_YEAST    704    737             
DBREF  3JAQ s   45    96  UNP    A6ZZ25   EIF3G_YEAS7     45     96             
DBREF  3JAQ 1    1    76  PDB    3JAQ     3JAQ             1     76             
DBREF  3JAQ 2    1  1798  PDB    3JAQ     3JAQ             1   1798             
DBREF  3JAQ 3   10    34  PDB    3JAQ     3JAQ            10     34             
DBREF  3JAQ o  753   866  PDB    3JAQ     3JAQ           753    866             
DBREF  3JAQ p   20   216  PDB    3JAQ     3JAQ            20    216             
SEQRES   1 1   75    A   G   C   G   C   C   G   U 1MG 2MG   C   G   C          
SEQRES   2 1   75    A   G H2U   G   G   A   A   G   C   G   C M2G   C          
SEQRES   3 1   75    A   G   G   G   C   U   C   A   U T6A   A   C   C          
SEQRES   4 1   75    C   U   G   A   U 7MG H2U 5MC 5MC   U   C   G   G          
SEQRES   5 1   75    A   U   C   G 1MA   A   A   C   C   G RIA   G   C          
SEQRES   6 1   75    G   G   C   G   C   U   A   C   C   A                      
SEQRES   1 2 1781    U   A   U   C   U   G   G   U   U   G   A   U   C          
SEQRES   2 2 1781    C   U   G   C   C   A   G   U   A   G   U   C   A          
SEQRES   3 2 1781    U   A   U   G   C   U   U   G   U   C   U   C   A          
SEQRES   4 2 1781    A   A   G   A   U   U   A   A   G   C   C   A   U          
SEQRES   5 2 1781    G   C   A   U   G   U   C   U   A   A   G   U   A          
SEQRES   6 2 1781    U   A   A   G   C   A   A   U   U   U   A   U   A          
SEQRES   7 2 1781    C   A   G   U   G   A   A   A   C   U   G   C   G          
SEQRES   8 2 1781    A   A   U   G   G   C   U   C   A   U   U   A   A          
SEQRES   9 2 1781    A   U   C   A   G   U   U   A   U   C   G   U   U          
SEQRES  10 2 1781    U   A   U   U   U   G   A   U   A   G   U   U   C          
SEQRES  11 2 1781    C   U   U   U   A   C   U   A   C   A   U   G   G          
SEQRES  12 2 1781    A   U   A   U   C   U   G   U   G   G   U   A   A          
SEQRES  13 2 1781    U   U   C   U   A   G   A   G   C   U   A   A   U          
SEQRES  14 2 1781    A   C   A   U   G   C   U   U   A   A   A   A   U          
SEQRES  15 2 1781    C   U   C   G   A   C   C   C   U   U   U   G   G          
SEQRES  16 2 1781    A   A   G   A   G   A   U   G   U   A   U   U   U          
SEQRES  17 2 1781    A   U   U   A   G   A   U   A   A   A   A   A   A          
SEQRES  18 2 1781    U   C   A   A   U   G   U   C   U   U   C   G   G          
SEQRES  19 2 1781    A   C   U   C   C   U   U   G   A   U   G   A   U          
SEQRES  20 2 1781    U   C   A   U   A   A   U   A   A   C   U   U   U          
SEQRES  21 2 1781    U   C   G   A   A   U   C   G   C   A   U   G   G          
SEQRES  22 2 1781    C   C   U   U   G   U   G   C   U   G   G   C   G          
SEQRES  23 2 1781    A   U   G   G   U   U   C   A   U   U   C   A   A          
SEQRES  24 2 1781    A   U   U   U   C   U   G   C   C   C   U   A   U          
SEQRES  25 2 1781    C   A   A   C   U   U   U   C   G   A   U   G   G          
SEQRES  26 2 1781    U   A   G   G   A   U   A   G   U   G   G   C   C          
SEQRES  27 2 1781    U   A   C   C   A   U   G   G   U   U   U   C   A          
SEQRES  28 2 1781    A   C   G   G   G   U   A   A   C   G   G   G   G          
SEQRES  29 2 1781    A   A   U   A   A   G   G   G   U   U   C   G   A          
SEQRES  30 2 1781    U   U   C   C   G   G   A   G   A   G   G   G   A          
SEQRES  31 2 1781    G   C   C   U   G   A   G   A   A   A   C   G   G          
SEQRES  32 2 1781    C   U   A   C   C   A   C   A   U   C   C   A   A          
SEQRES  33 2 1781    G   G   A   A   G   G   C   A   G   C   A   G   G          
SEQRES  34 2 1781    C   G   C   G   C   A   A   A   U   U   A   C   C          
SEQRES  35 2 1781    C   A   A   U   C   C   U   A   A   U   U   C   A          
SEQRES  36 2 1781    G   G   G   A   G   G   U   A   G   U   G   A   C          
SEQRES  37 2 1781    A   A   U   A   A   A   U   A   A   C   G   A   U          
SEQRES  38 2 1781    A   C   A   G   G   G   C   C   C   A   U   U   C          
SEQRES  39 2 1781    G   G   G   U   C   U   U   G   U   A   A   U   U          
SEQRES  40 2 1781    G   G   A   A   U   G   A   G   U   A   C   A   A          
SEQRES  41 2 1781    U   G   U   A   A   A   U   A   C   C   U   U   A          
SEQRES  42 2 1781    A   C   G   A   G   G   A   A   C   A   A   C   U          
SEQRES  43 2 1781    G   G   A   G   G   G   C   A   A   G   U   C   U          
SEQRES  44 2 1781    G   G   U   G   C   C   A   G   C   A   G   C   C          
SEQRES  45 2 1781    G   C   G   G   U   A   A   U   U   C   C   A   G          
SEQRES  46 2 1781    C   U   C   C   A   G   U   A   G   C   G   U   A          
SEQRES  47 2 1781    U   A   U   U   A   A   A   G   U   U   G   U   U          
SEQRES  48 2 1781    G   C   A   G   U   U   A   A   A   A   A   G   C          
SEQRES  49 2 1781    U   C   G   U   A   G   U   U   G   A   A   C   U          
SEQRES  50 2 1781    U   U   G   G   G   U   C   U   G   G   U   U   G          
SEQRES  51 2 1781    U   C   C   G   G   U   C   C   G   G   U   U   U          
SEQRES  52 2 1781    U   U   C   A   A   C   C   G   G   A   U   C   U          
SEQRES  53 2 1781    U   U   C   C   U   U   C   U   G   G   C   U   A          
SEQRES  54 2 1781    A   C   C   U   G   U   A   C   U   C   C   U   U          
SEQRES  55 2 1781    G   U   G   G   G   U   G   C   A   G   G   C   G          
SEQRES  56 2 1781    A   A   C   C   A   G   G   A   C   U   U   U   U          
SEQRES  57 2 1781    A   C   U   U   U   G   A   A   A   A   A   A   U          
SEQRES  58 2 1781    U   A   G   A   G   U   G   U   U   C   A   A   A          
SEQRES  59 2 1781    G   C   A   G   G   C   G   A   A   A   G   C   U          
SEQRES  60 2 1781    C   G   A   A   U   A   U   A   U   U   A   G   C          
SEQRES  61 2 1781    A   U   G   G   A   A   U   A   A   U   G   G   A          
SEQRES  62 2 1781    A   U   A   G   G   A   C   G   U   U   U   G   G          
SEQRES  63 2 1781    U   U   C   U   A   U   U   U   U   G   U   U   G          
SEQRES  64 2 1781    G   U   U   U   C   U   A   G   G   A   C   C   A          
SEQRES  65 2 1781    U   C   G   U   A   A   U   G   A   U   U   A   A          
SEQRES  66 2 1781    U   A   G   G   G   A   C   G   G   U   C   G   G          
SEQRES  67 2 1781    G   G   G   C   A   U   C   A   G   U   A   U   U          
SEQRES  68 2 1781    C   A   A   U   U   G   U   C   A   G   A   G   G          
SEQRES  69 2 1781    U   G   A   A   A   U   U   C   U   U   G   G   A          
SEQRES  70 2 1781    U   U   U   A   U   U   G   A   A   G   A   C   U          
SEQRES  71 2 1781    A   A   C   U   A   C   U   G   C   G   A   A   A          
SEQRES  72 2 1781    G   C   A   U   U   U   G   C   C   A   A   G   G          
SEQRES  73 2 1781    A   C   G   U   U   U   U   C   A   U   U   A   A          
SEQRES  74 2 1781    U   C   A   A   G   A   A   C   G   A   A   A   G          
SEQRES  75 2 1781    U   U   A   G   G   G   G   A   U   C   G   A   A          
SEQRES  76 2 1781    G   A   U   G   A   U   C   A   G   A   U   A   C          
SEQRES  77 2 1781    C   G   U   C   G   U   A   G   U   C   U   U   A          
SEQRES  78 2 1781    A   C   C   A   U   A   A   A   C   U   A   U   G          
SEQRES  79 2 1781    C   C   G   A   C   U   A   G   G   G   A   U   C          
SEQRES  80 2 1781    G   G   G   U   G   G   U   G   U   U   U   U   U          
SEQRES  81 2 1781    C   U   U   A   U   G   A   C   C   C   A   C   U          
SEQRES  82 2 1781    C   G   G   C   A   C   C   U   U   A   C   G   A          
SEQRES  83 2 1781    G   A   A   A   U   C   A   A   A   G   U   C   U          
SEQRES  84 2 1781    U   U   G   G   G   U   U   C   U   G   G   G   G          
SEQRES  85 2 1781    G   G   A   G   U   A   U   G   G   U   C   G   C          
SEQRES  86 2 1781    A   A   G   G   C   U   G   A   A   A   C   U   U          
SEQRES  87 2 1781    A   A   A   G   G   A   A   U   U   G   A   C   G          
SEQRES  88 2 1781    G   A   A   G   G   G   C   A   C   C   A   C   C          
SEQRES  89 2 1781    A   G   G   A   G   U   G   G   A   G   C   C   U          
SEQRES  90 2 1781    G   C   G   G   C   U   U   A   A   U   U   U   G          
SEQRES  91 2 1781    A   C   U   C   A   A   C   A   C   G   G   G   G          
SEQRES  92 2 1781    A   A   A   C   U   C   A   C   C   A   G   G   U          
SEQRES  93 2 1781    C   C   A   G   A   C   A   C   A   A   U   A   A          
SEQRES  94 2 1781    G   G   A   U   U   G   A   C   A   G   A   U   U          
SEQRES  95 2 1781    G   A   G   A   G   C   U   C   U   U   U   C   U          
SEQRES  96 2 1781    U   G   A   U   U   U   U   G   U   G   G   G   U          
SEQRES  97 2 1781    G   G   U   G   G   U   G   C   A   U   G   G   C          
SEQRES  98 2 1781    C   G   U   U   C   U   U   A   G   U   U   G   G          
SEQRES  99 2 1781    U   G   G   A   G   U   G   A   U   U   U   G   U          
SEQRES 100 2 1781    C   U   G   C   U   U   A   A   U   U   G   C   G          
SEQRES 101 2 1781    A   U   A   A   C   G   A   A   C   G   A   G   A          
SEQRES 102 2 1781    C   C   U   U   A   A   C   C   U   A   C   U   A          
SEQRES 103 2 1781    A   A   U   A   G   G   G   U   U   G   C   U   G          
SEQRES 104 2 1781    G   C   A   C   U   U   G   C   C   G   G   U   U          
SEQRES 105 2 1781    G   A   C   U   C   U   U   C   U   U   A   G   A          
SEQRES 106 2 1781    G   G   G   A   C   U   A   U   C   G   G   U   U          
SEQRES 107 2 1781    U   C   A   A   G   C   C   G   A   U   G   G   A          
SEQRES 108 2 1781    A   G   U   U   U   G   A   G   G   C   A   A   U          
SEQRES 109 2 1781    A   A   C   A   G   G   U   C   U   G   U   G   A          
SEQRES 110 2 1781    U   G   C   C   C   U   U   A   G   A   C   G   U          
SEQRES 111 2 1781    U   C   U   G   G   G   C   C   G   C   A   C   G          
SEQRES 112 2 1781    C   G   C   G   C   U   A   C   A   C   U   G   A          
SEQRES 113 2 1781    C   G   G   A   G   C   C   A   G   C   G   A   G          
SEQRES 114 2 1781    U   A   C   A   A   C   C   U   U   G   G   C   C          
SEQRES 115 2 1781    G   A   G   A   G   G   U   C   U   G   G   G   U          
SEQRES 116 2 1781    A   A   U   C   U   U   G   U   G   A   A   A   C          
SEQRES 117 2 1781    U   C   C   G   U   C   G   U   G   C   U   G   G          
SEQRES 118 2 1781    G   G   A   U   A   G   A   G   C   A   U   U   G          
SEQRES 119 2 1781    U   A   A   U   U   A   U   U   G   C   U   C   U          
SEQRES 120 2 1781    U   C   A   A   C   G   A   G   G   A   A   U   U          
SEQRES 121 2 1781    C   C   U   A   G   U   A   A   G   C   G   C   A          
SEQRES 122 2 1781    A   G   U   C   A   U   C   A   G   C   U   U   G          
SEQRES 123 2 1781    C   G   U   U   G   A   U   U   A   C   G   U   C          
SEQRES 124 2 1781    C   C   U   G   C   C   C   U   U   U   G   U   A          
SEQRES 125 2 1781    C   A   C   A   C   C   G   C   C   C   G   U   C          
SEQRES 126 2 1781    G   C   U   A   G   U   A   C   C   G   A   U   U          
SEQRES 127 2 1781    G   A   A   U   G   G   C   U   U   A   G   U   G          
SEQRES 128 2 1781    A   G   G   C   C   U   C   A   G   G   A   U   U          
SEQRES 129 2 1781    U   G   C   U   U   A   G   A   G   A   A   G   G          
SEQRES 130 2 1781    G   G   G   C   A   A   C   U   C   C   A   U   C          
SEQRES 131 2 1781    U   C   A   G   A   G   C   G   A   A   G   A   A          
SEQRES 132 2 1781    U   C   U   G   G   U   C   A   A   A   C   U   U          
SEQRES 133 2 1781    G   G   U   C   A   U   U   U   A   G   A   G   G          
SEQRES 134 2 1781    A   A   C   U   A   A   A   A   G   U   C   G   U          
SEQRES 135 2 1781    A   A   C   A   A   G   G   U   U   U   C   C   G          
SEQRES 136 2 1781    U   A   G   G   U   G   A   A   C   C   U   G   C          
SEQRES 137 2 1781    G   G   A   A   G   G   A   U   C   A   U   U   A          
SEQRES   1 3   25    G   G   A   A   U   C   U   C   U   C   U   C   U          
SEQRES   2 3   25    A   U   C   C   U   C   U   C   U   C   U   C              
SEQRES   1 A  254  MET SER LEU PRO SER THR PHE ASP LEU THR SER GLU ASP          
SEQRES   2 A  254  ALA GLN LEU LEU LEU ALA ALA ARG VAL HIS LEU GLY ALA          
SEQRES   3 A  254  LYS ASN VAL GLN VAL HIS GLN GLU PRO TYR VAL TYR LYS          
SEQRES   4 A  254  ALA ARG PRO ASP GLY VAL ASN VAL ILE ASN VAL GLY LYS          
SEQRES   5 A  254  THR TRP GLU LYS ILE VAL LEU ALA ALA ARG ILE ILE ALA          
SEQRES   6 A  254  ALA ILE PRO ASN PRO GLU ASP VAL VAL ALA ILE SER SER          
SEQRES   7 A  254  ARG THR TYR GLY GLN ARG ALA VAL LEU LYS TYR ALA ALA          
SEQRES   8 A  254  HIS THR GLY ALA THR PRO ILE ALA GLY ARG PHE THR PRO          
SEQRES   9 A  254  GLY SER PHE THR ASN TYR ILE THR ARG SER PHE LYS GLU          
SEQRES  10 A  254  PRO ARG LEU VAL ILE VAL THR ASP PRO ARG SER ASP ALA          
SEQRES  11 A  254  GLN ALA ILE LYS GLU SER SER TYR VAL ASN ILE PRO VAL          
SEQRES  12 A  254  ILE ALA LEU THR ASP LEU ASP SER PRO SER GLU TYR VAL          
SEQRES  13 A  254  ASP VAL ALA ILE PRO CYS ASN ASN ARG GLY LYS HIS SER          
SEQRES  14 A  254  ILE GLY LEU ILE TRP TYR LEU LEU ALA ARG GLU VAL LEU          
SEQRES  15 A  254  ARG LEU ARG GLY ALA LEU PRO ASP ARG THR GLN PRO TRP          
SEQRES  16 A  254  ALA ILE MET PRO ASP LEU TYR PHE TYR ARG ASN PRO GLU          
SEQRES  17 A  254  GLU ILE GLU GLN GLN THR ALA GLU GLU GLU ALA VAL ALA          
SEQRES  18 A  254  SER GLY GLU GLN THR GLU GLU ALA VAL ASP ALA THR GLU          
SEQRES  19 A  254  GLU GLN THR GLU ALA ALA GLU TRP ALA GLU GLU GLY GLN          
SEQRES  20 A  254  ALA GLN GLU GLU GLU TRP ASN                                  
SEQRES   1 B  255  MET ALA VAL GLY LYS ASN LYS ARG LEU SER LYS GLY LYS          
SEQRES   2 B  255  LYS GLY LEU LYS LYS ARG VAL VAL ASP PRO PHE THR ARG          
SEQRES   3 B  255  LYS GLU TRP TYR ASP ILE LYS ALA PRO SER THR PHE GLU          
SEQRES   4 B  255  ASN ARG ASN VAL GLY LYS THR LEU VAL ASN LYS SER VAL          
SEQRES   5 B  255  GLY LEU LYS ASN ALA SER ASP SER LEU LYS GLY ARG VAL          
SEQRES   6 B  255  VAL GLU VAL CYS LEU ALA ASP LEU GLN GLY SER GLU ASP          
SEQRES   7 B  255  HIS SER PHE ARG LYS VAL LYS LEU ARG VAL ASP GLU VAL          
SEQRES   8 B  255  GLN GLY LYS ASN LEU LEU THR ASN PHE HIS GLY MET ASP          
SEQRES   9 B  255  PHE THR THR ASP LYS LEU ARG SER MET VAL ARG LYS TRP          
SEQRES  10 B  255  GLN THR LEU ILE GLU ALA ASN VAL THR VAL LYS THR SER          
SEQRES  11 B  255  ASP ASP TYR VAL LEU ARG ILE PHE ALA ILE ALA PHE THR          
SEQRES  12 B  255  ARG LYS GLN ALA ASN GLN VAL LYS ARG THR SER TYR ALA          
SEQRES  13 B  255  GLN SER SER HIS ILE ARG GLN ILE ARG LYS VAL ILE SER          
SEQRES  14 B  255  GLU ILE LEU THR ARG GLU VAL GLN ASN SER THR LEU ALA          
SEQRES  15 B  255  GLN LEU THR SER LYS LEU ILE PRO GLU VAL ILE ASN LYS          
SEQRES  16 B  255  GLU ILE GLU ASN ALA THR LYS ASP ILE PHE PRO LEU GLN          
SEQRES  17 B  255  ASN VAL HIS ILE ARG LYS VAL LYS LEU LEU LYS GLN PRO          
SEQRES  18 B  255  LYS PHE ASP LEU GLY SER LEU LEU SER LEU HIS GLY GLU          
SEQRES  19 B  255  ALA SER ALA GLU GLU LYS GLY LYS LYS VAL ALA GLY PHE          
SEQRES  20 B  255  LYS ASP GLU ILE LEU GLU THR VAL                              
SEQRES   1 C  259  MET SER ALA PRO GLN ALA GLN GLY GLN GLN ALA PRO ARG          
SEQRES   2 C  259  ARG GLY GLY PHE GLY GLY ALA ASN ARG GLY GLY ARG GLY          
SEQRES   3 C  259  GLY ARG ARG GLY GLY ARG ARG ASP GLN GLU GLU LYS GLY          
SEQRES   4 C  259  TRP VAL PRO VAL THR LYS LEU GLY ARG LEU VAL LYS ALA          
SEQRES   5 C  259  GLY LYS ILE SER SER ILE GLU GLU ILE PHE LEU HIS SER          
SEQRES   6 C  259  LEU PRO VAL LYS GLU PHE GLN ILE ILE ASP GLN LEU LEU          
SEQRES   7 C  259  PRO ASN LEU LYS ASP GLU VAL MET ASN ILE LYS PRO VAL          
SEQRES   8 C  259  GLN LYS GLN THR ARG ALA GLY GLN ARG THR ARG PHE LYS          
SEQRES   9 C  259  ALA VAL VAL VAL VAL GLY ASP SER ASN GLY HIS VAL GLY          
SEQRES  10 C  259  LEU GLY ILE LYS THR ALA LYS GLU VAL ALA GLY ALA ILE          
SEQRES  11 C  259  ARG ALA GLY ILE ILE ILE ALA LYS LEU SER VAL ILE PRO          
SEQRES  12 C  259  ILE ARG ARG GLY TYR TRP GLY THR ASN LEU GLY GLN PRO          
SEQRES  13 C  259  HIS SER LEU ALA THR LYS THR SER GLY LYS CYS GLY SER          
SEQRES  14 C  259  VAL SER VAL ARG LEU ILE PRO ALA PRO ARG GLY SER GLY          
SEQRES  15 C  259  ILE VAL ALA SER PRO ALA VAL LYS LYS LEU MET GLN LEU          
SEQRES  16 C  259  ALA GLY VAL GLU ASP VAL TYR THR SER SER THR GLY SER          
SEQRES  17 C  259  THR ARG THR LEU GLU ASN THR LEU LYS ALA ALA PHE VAL          
SEQRES  18 C  259  ALA ILE GLY ASN THR TYR GLY PHE LEU THR PRO ASN LEU          
SEQRES  19 C  259  TRP GLU VAL GLN ALA LEU THR PRO SER PRO MET ASP VAL          
SEQRES  20 C  259  TYR ALA ASP TYR ALA THR ALA SER LYS LYS LYS LEU              
SEQRES   1 D  237  MET VAL ALA ILE ILE SER LYS LYS ARG LYS LEU VAL ALA          
SEQRES   2 D  237  ASP GLY VAL PHE TYR ALA GLU LEU ASN GLU PHE PHE THR          
SEQRES   3 D  237  ARG GLU LEU ALA GLU GLU GLY TYR SER GLY VAL GLU VAL          
SEQRES   4 D  237  ARG VAL THR PRO THR LYS THR GLU ILE ILE ILE ARG ALA          
SEQRES   5 D  237  THR LYS VAL GLN ASP VAL VAL GLY GLU ASN GLY ARG ARG          
SEQRES   6 D  237  ILE ASN GLU LEU THR LEU LEU ILE GLU LYS ARG PHE LYS          
SEQRES   7 D  237  TYR LYS ARG GLY THR ILE ALA LEU TYR ALA GLU ARG VAL          
SEQRES   8 D  237  HIS ASP ARG GLY LEU SER ALA VAL ALA GLN ALA GLU SER          
SEQRES   9 D  237  MET LYS PHE LYS LEU LEU ASN GLY LEU ALA ILE ARG ARG          
SEQRES  10 D  237  ALA ALA TYR GLY VAL VAL ARG TYR VAL MET GLU SER GLY          
SEQRES  11 D  237  ALA LYS GLY CYS GLU VAL VAL ILE SER GLY LYS LEU ARG          
SEQRES  12 D  237  ALA ALA ARG ALA LYS SER MET LYS PHE ALA ASP GLY PHE          
SEQRES  13 D  237  LEU ILE HIS SER GLY GLN PRO VAL ASN ASP PHE ILE GLU          
SEQRES  14 D  237  THR ALA THR ARG HIS VAL LEU LEU ARG GLN GLY VAL LEU          
SEQRES  15 D  237  GLY ILE LYS VAL LYS ILE MET LYS ASP PRO SER ARG ASN          
SEQRES  16 D  237  THR SER GLY PRO LYS ALA LEU PRO ASP ALA VAL THR ILE          
SEQRES  17 D  237  ILE GLU PRO LYS GLU GLU GLU PRO VAL LEU GLU PRO SER          
SEQRES  18 D  237  VAL LYS ASP TYR ARG PRO THR GLU PRO VAL GLU ALA ALA          
SEQRES  19 D  237  GLU SER ALA                                                  
SEQRES   1 E  261  MET ALA ARG GLY PRO LYS LYS HIS LEU LYS ARG LEU ALA          
SEQRES   2 E  261  ALA PRO HIS HIS TRP MET LEU ASP LYS LEU SER GLY CYS          
SEQRES   3 E  261  TYR ALA PRO ARG PRO SER ALA GLY PRO HIS LYS LEU ARG          
SEQRES   4 E  261  GLU SER LEU PRO LEU ILE VAL PHE LEU ARG ASN ARG LEU          
SEQRES   5 E  261  LYS TYR ALA LEU ASN GLY ARG GLU VAL LYS ALA ILE LEU          
SEQRES   6 E  261  MET GLN ARG HIS VAL LYS VAL ASP GLY LYS VAL ARG THR          
SEQRES   7 E  261  ASP THR THR PHE PRO ALA GLY PHE MET ASP VAL ILE THR          
SEQRES   8 E  261  LEU GLU ALA THR ASN GLU ASN PHE ARG LEU VAL TYR ASP          
SEQRES   9 E  261  VAL LYS GLY ARG PHE ALA VAL HIS ARG ILE THR ASP GLU          
SEQRES  10 E  261  GLU ALA SER TYR LYS LEU ALA LYS VAL LYS LYS VAL GLN          
SEQRES  11 E  261  LEU GLY LYS LYS GLY ILE PRO TYR VAL VAL THR HIS ASP          
SEQRES  12 E  261  GLY ARG THR ILE ARG TYR PRO ASP PRO ASN ILE LYS VAL          
SEQRES  13 E  261  ASN ASP THR VAL LYS VAL ASP LEU ALA THR GLY THR ILE          
SEQRES  14 E  261  THR ASP PHE ILE LYS PHE ASP THR GLY LYS LEU VAL TYR          
SEQRES  15 E  261  VAL THR GLY GLY ARG ASN LEU GLY ARG VAL GLY THR ILE          
SEQRES  16 E  261  VAL HIS ARG GLU ARG HIS GLU GLY GLY PHE ASP LEU VAL          
SEQRES  17 E  261  HIS ILE LYS ASP SER LEU GLU ASN THR PHE VAL THR ARG          
SEQRES  18 E  261  LEU ASN ASN VAL PHE VAL ILE GLY GLU PRO GLY ARG PRO          
SEQRES  19 E  261  TRP ILE SER LEU PRO LYS GLY LYS GLY ILE LYS LEU THR          
SEQRES  20 E  261  ILE SER GLU GLU ARG ASP ARG ARG ARG ALA GLN HIS GLY          
SEQRES  21 E  261  LEU                                                          
SEQRES   1 F  227  MET SER GLU HIS GLU ALA GLN VAL GLU VAL GLU VAL GLN          
SEQRES   2 F  227  GLU ASP PHE GLU VAL VAL GLN GLU PHE VAL PRO VAL GLU          
SEQRES   3 F  227  LEU ALA THR THR ILE PRO VAL GLU ILE GLN GLN ALA GLN          
SEQRES   4 F  227  GLN GLU ILE LYS LEU PHE ASN LYS TRP SER PHE GLU ASP          
SEQRES   5 F  227  VAL GLU VAL LYS ASP ALA SER LEU VAL ASP TYR ILE GLN          
SEQRES   6 F  227  ILE SER LYS PRO ILE TYR VAL ALA HIS THR ALA GLY ARG          
SEQRES   7 F  227  TYR ALA ASN LYS ARG PHE ARG LYS ALA GLN CYS PRO ILE          
SEQRES   8 F  227  VAL GLU ARG LEU THR ASN SER LEU MET MET ASN GLY ARG          
SEQRES   9 F  227  ASN ASN GLY LYS LYS LEU LYS ALA VAL ARG ILE VAL LYS          
SEQRES  10 F  227  HIS THR LEU GLU ILE ILE ASN VAL LEU THR ASP GLN ASN          
SEQRES  11 F  227  PRO LEU GLN VAL VAL VAL ASP ALA ILE ILE ASN SER GLY          
SEQRES  12 F  227  PRO ARG GLU ASP THR THR ARG VAL GLY GLY GLY GLY ALA          
SEQRES  13 F  227  ALA ARG ARG GLN ALA VAL ASP VAL SER PRO LEU ARG ARG          
SEQRES  14 F  227  VAL ASN GLN SER ILE ALA LEU LEU THR ILE GLY ALA ARG          
SEQRES  15 F  227  GLU ALA ALA PHE ARG ASN ILE LYS THR ILE ALA GLU THR          
SEQRES  16 F  227  LEU ALA GLU GLU LEU ILE ASN ALA ALA LYS GLY SER SER          
SEQRES  17 F  227  THR SER TYR ALA ILE LYS LYS LYS ASP GLU LEU GLU ARG          
SEQRES  18 F  227  VAL ALA LYS SER ASN ARG                                      
SEQRES   1 G  236  MET LYS LEU ASN ILE SER TYR PRO ILE ASN GLY THR GLN          
SEQRES   2 G  236  LYS CYS ILE GLU ILE ASP ASP GLU HIS ARG VAL ARG VAL          
SEQRES   3 G  236  PHE TYR ASP LYS ARG ILE GLY GLN GLU VAL ASP GLY GLU          
SEQRES   4 G  236  SER VAL GLY ASP GLU PHE LYS GLY TYR VAL PHE LYS ILE          
SEQRES   5 G  236  ALA GLY GLY ASN ASP LYS GLN GLY PHE PRO MET LYS GLN          
SEQRES   6 G  236  GLY VAL LEU LEU PRO THR ARG VAL LYS LEU LEU LEU ALA          
SEQRES   7 G  236  LYS GLY HIS SER CYS TYR ARG PRO ARG ARG ASN GLY GLU          
SEQRES   8 G  236  ARG LYS ARG LYS SER VAL ARG GLY ALA ILE VAL GLY PRO          
SEQRES   9 G  236  ASP LEU ALA VAL LEU ALA LEU ILE ILE THR LYS LYS GLY          
SEQRES  10 G  236  GLU GLN GLU ILE GLU GLY ILE THR ASN ASP THR VAL PRO          
SEQRES  11 G  236  LYS ARG LEU GLY PRO LYS ARG ALA ASN ASN ILE ARG LYS          
SEQRES  12 G  236  PHE PHE GLY LEU THR LYS GLU ASP ASP VAL ARG ASP TYR          
SEQRES  13 G  236  VAL ILE ARG ARG GLU VAL THR LYS GLY ASP LYS SER TYR          
SEQRES  14 G  236  THR LYS ALA PRO LYS ILE GLN ARG LEU VAL THR PRO GLN          
SEQRES  15 G  236  ARG LEU GLN ARG LYS ARG GLN GLN LYS SER LEU LYS ILE          
SEQRES  16 G  236  LYS ASN ALA GLN ALA GLN ARG GLU ALA ALA ALA GLU TYR          
SEQRES  17 G  236  ALA GLN LEU LEU ALA LYS ARG LEU SER GLU ARG LYS ALA          
SEQRES  18 G  236  GLU LYS ALA GLU VAL ARG LYS ARG ARG ALA SER SER LEU          
SEQRES  19 G  236  LYS ALA                                                      
SEQRES   1 H  190  MET SER ASP PRO GLN ALA LYS ILE LEU SER GLN ALA PRO          
SEQRES   2 H  190  THR GLU LEU GLU LEU GLN VAL ALA GLN ALA PHE ILE ASP          
SEQRES   3 H  190  LEU GLU ASN ASN SER PRO GLU LEU LYS ALA ASP LEU ARG          
SEQRES   4 H  190  ALA LEU GLN PHE LYS SER ILE ARG GLU ILE GLU VAL ALA          
SEQRES   5 H  190  GLY GLY LYS LYS ALA LEU ALA VAL PHE VAL PRO VAL PRO          
SEQRES   6 H  190  SER LEU ALA ALA TYR HIS LYS VAL GLN ILE LYS LEU THR          
SEQRES   7 H  190  ARG GLU LEU GLU LYS LYS PHE GLN ASP ARG HIS VAL ILE          
SEQRES   8 H  190  PHE LEU ALA GLU ARG ARG ILE LEU PRO LYS PRO SER ARG          
SEQRES   9 H  190  LYS SER ARG GLN THR GLN LYS ARG PRO ARG SER ARG THR          
SEQRES  10 H  190  LEU THR ALA VAL HIS ASP LYS ILE LEU GLU ASP LEU VAL          
SEQRES  11 H  190  PHE PRO THR GLU ILE VAL GLY LYS ARG VAL ARG TYR LEU          
SEQRES  12 H  190  VAL GLY GLY ASN LYS ILE GLN LYS ILE LEU LEU ASN SER          
SEQRES  13 H  190  LYS ASP VAL GLN HIS ILE ASP ASN LYS LEU GLU SER PHE          
SEQRES  14 H  190  GLN ALA VAL TYR ASN LYS LEU THR GLY LYS GLN ILE VAL          
SEQRES  15 H  190  PHE GLU ILE PRO SER GLU THR HIS                              
SEQRES   1 I  201  MET GLY ILE SER ARG ASP SER ARG HIS LYS ARG ALA ALA          
SEQRES   2 I  201  THR GLY ALA LYS ARG ALA GLN PHE ARG LYS LYS ARG LYS          
SEQRES   3 I  201  PHE GLU LEU GLY ARG GLN ALA ALA ASN THR LYS ILE GLY          
SEQRES   4 I  201  THR LYS ARG ILE HIS PRO VAL ARG THR ARG GLY GLY ASN          
SEQRES   5 I  201  GLN LYS PHE ARG ALA LEU ARG ILE GLU THR GLY ASN PHE          
SEQRES   6 I  201  SER TRP ALA SER GLU GLY VAL ALA ARG LYS THR ARG ILE          
SEQRES   7 I  201  THR GLY VAL VAL TYR HIS PRO SER ASN ASN GLU LEU VAL          
SEQRES   8 I  201  ARG THR ASN THR LEU THR LYS ALA ALA ILE VAL GLN ILE          
SEQRES   9 I  201  ASP ALA THR PRO PHE ARG GLN TRP TYR GLU SER HIS TYR          
SEQRES  10 I  201  GLY GLN SER LEU GLY LYS LYS LYS ASN THR LYS ALA GLU          
SEQRES  11 I  201  GLU GLU THR ALA THR THR SER LYS ASN THR GLU ARG LYS          
SEQRES  12 I  201  TRP ALA ALA ARG ALA ALA GLU ALA LYS ILE GLU HIS ALA          
SEQRES  13 I  201  VAL ASP SER GLN PHE GLY ALA GLY ARG LEU TYR ALA ALA          
SEQRES  14 I  201  ILE SER SER ARG PRO GLY GLN SER GLY ARG CYS ASP GLY          
SEQRES  15 I  201  TYR ILE LEU GLU GLY GLU GLU LEU ALA PHE TYR LEU ARG          
SEQRES  16 I  201  ARG LEU THR ALA LYS LYS                                      
SEQRES   1 J  188  MET PRO ARG ALA PRO ARG THR TYR SER LYS THR TYR SER          
SEQRES   2 J  188  THR PRO LYS ARG PRO TYR GLU SER ALA ARG LEU ASP ALA          
SEQRES   3 J  188  GLU LEU LYS LEU ALA GLY GLU TYR GLY LEU LYS ASN LYS          
SEQRES   4 J  188  ARG GLU ILE TYR ARG ILE SER PHE GLN LEU SER LYS ILE          
SEQRES   5 J  188  ARG ARG ALA ALA ARG ASP LEU LEU THR ARG ASP GLU LYS          
SEQRES   6 J  188  ASP PRO LYS ARG LEU PHE GLU GLY ASN ALA LEU ILE ARG          
SEQRES   7 J  188  ARG LEU VAL ARG ILE GLY VAL LEU SER GLU ASP LYS LYS          
SEQRES   8 J  188  LYS LEU ASP TYR VAL LEU ALA LEU LYS VAL GLU ASP PHE          
SEQRES   9 J  188  LEU GLU ARG ARG LEU GLN THR GLN VAL TYR LYS LEU GLY          
SEQRES  10 J  188  LEU ALA LYS SER VAL HIS HIS ALA ARG VAL LEU ILE SER          
SEQRES  11 J  188  GLN ARG HIS ILE ALA VAL GLY LYS GLN ILE VAL ASN ILE          
SEQRES  12 J  188  PRO SER PHE MET VAL ARG LEU GLU SER GLU LYS HIS ILE          
SEQRES  13 J  188  ASP PHE ALA ARG THR SER PRO PHE GLY GLY ALA ARG PRO          
SEQRES  14 J  188  GLY ARG VAL ALA ARG LYS ARG ALA ALA ALA ALA GLY GLY          
SEQRES  15 J  188  GLU GLU ALA ASP GLU GLU                                      
SEQRES   1 K  106  MET LEU ILE PRO LYS GLU ASP ARG LYS LYS ILE TYR GLN          
SEQRES   2 K  106  HIS LEU PHE GLN GLU GLY VAL LEU VAL ALA LYS LYS ASP          
SEQRES   3 K  106  PHE ASN GLN PRO LYS HIS GLU GLU ILE ASP THR LYS ASN          
SEQRES   4 K  106  LEU PHE VAL ILE LYS ALA LEU GLN SER LEU THR SER LYS          
SEQRES   5 K  106  GLY PHE VAL LYS THR GLN PHE SER TRP GLN TYR TYR TYR          
SEQRES   6 K  106  TYR THR LEU THR GLU GLU GLY VAL VAL TYR LEU ARG GLU          
SEQRES   7 K  106  TYR LEU ASN LEU PRO GLU HIS ILE PHE PRO ALA THR TYR          
SEQRES   8 K  106  LEU ALA GLY GLN SER GLY ASP GLN ARG PRO GLN GLY LYS          
SEQRES   9 K  106  LYS TYR                                                      
SEQRES   1 L  156  MET SER THR GLU LEU THR VAL GLN SER GLU ARG ALA PHE          
SEQRES   2 L  156  GLN LYS GLN PRO HIS ILE PHE THR ASN PRO LYS ALA LYS          
SEQRES   3 L  156  ALA ASN ARG LYS THR LYS ARG TRP TYR LYS ASN VAL GLY          
SEQRES   4 L  156  LEU GLY PHE LYS THR PRO LYS THR ALA ILE GLU GLY SER          
SEQRES   5 L  156  TYR ILE ASP LYS LYS CYS PRO PHE THR GLY LEU VAL SER          
SEQRES   6 L  156  ILE ARG GLY LYS ILE LEU THR GLY THR VAL VAL SER THR          
SEQRES   7 L  156  ARG MET HIS ARG THR ILE VAL ILE ARG ARG ASP TYR LEU          
SEQRES   8 L  156  HIS TYR VAL PRO LYS TYR ASN ARG TYR GLU LYS ARG HIS          
SEQRES   9 L  156  LYS ASN VAL PRO ALA HIS VAL SER PRO ALA PHE ARG VAL          
SEQRES  10 L  156  GLN VAL GLY ASP ILE VAL THR VAL GLY GLN CYS ARG PRO          
SEQRES  11 L  156  ILE SER LYS THR VAL ARG PHE ASN VAL LEU LYS VAL ALA          
SEQRES  12 L  156  SER ALA THR GLY LYS ALA ASN LYS GLN PHE ALA LYS PHE          
SEQRES   1 M  134  MET SER ASP VAL GLU GLU VAL GLN GLN VAL PRO VAL ALA          
SEQRES   2 M  134  GLU LEU THR ILE GLU ASP ALA LEU LYS VAL VAL LEU ARG          
SEQRES   3 M  134  THR SER LEU VAL HIS ASP GLY LEU ALA ARG GLY LEU ARG          
SEQRES   4 M  134  GLU SER ALA LYS ALA LEU THR ARG GLY GLU GLY GLN LEU          
SEQRES   5 M  134  ALA VAL LEU VAL GLU SER VAL THR GLU GLU ALA ILE SER          
SEQRES   6 M  134  LYS LEU VAL GLN GLY LEU ALA THR GLU ASN ASN VAL PRO          
SEQRES   7 M  134  LEU ILE LYS VAL ALA ASP ALA LYS GLN LEU GLY GLU TRP          
SEQRES   8 M  134  ALA GLY LEU GLY LYS ILE ASP ARG ASP GLY ASN ALA ARG          
SEQRES   9 M  134  LYS VAL VAL GLY ALA SER VAL VAL VAL VAL LYS ASN TRP          
SEQRES  10 M  134  GLY ALA ASP THR GLN GLU ARG GLU ILE LEU LEU GLU HIS          
SEQRES  11 M  134  PHE SER GLN GLN                                              
SEQRES   1 N  151  MET GLY ARG MET HIS SER LYS GLY LYS GLY MET SER SER          
SEQRES   2 N  151  SER ALA ILE PRO TYR SER ARG ASN ALA PRO ALA TRP PHE          
SEQRES   3 N  151  LYS GLY SER SER ASP GLY VAL VAL GLU GLN ILE ILE LYS          
SEQRES   4 N  151  TYR ALA ARG LYS GLY LEU THR PRO SER GLN ILE GLY VAL          
SEQRES   5 N  151  LEU LEU ARG ASP ALA HIS GLY VAL THR GLN ALA LYS VAL          
SEQRES   6 N  151  ILE THR GLY ASN LYS ILE LEU ARG ILE LEU LYS SER ASN          
SEQRES   7 N  151  GLY LEU ALA PRO GLU ILE PRO GLU ASP LEU TYR PHE LEU          
SEQRES   8 N  151  ILE LYS LYS ALA VAL SER VAL ARG LYS HIS LEU GLU ARG          
SEQRES   9 N  151  ASN ARG LYS ASP LYS ASP ALA LYS PHE ARG LEU ILE LEU          
SEQRES  10 N  151  ILE GLU SER ARG ILE HIS ARG LEU ALA ARG TYR TYR ARG          
SEQRES  11 N  151  THR VAL SER VAL LEU PRO PRO ASN TRP LYS TYR GLU SER          
SEQRES  12 N  151  ALA THR ALA SER ALA LEU VAL ASN                              
SEQRES   1 O  137  MET ALA ASN VAL VAL GLN ALA LYS ASP ASN SER GLN VAL          
SEQRES   2 O  137  PHE GLY VAL ALA ARG ILE PHE ALA SER PHE ASN ASP THR          
SEQRES   3 O  137  PHE VAL HIS VAL THR ASP LEU SER GLY ARG GLU THR ILE          
SEQRES   4 O  137  ALA ARG VAL THR GLY GLY MET LYS VAL LYS ALA ASP ARG          
SEQRES   5 O  137  ASP GLU SER SER PRO TYR ALA ALA MET LEU ALA ALA GLN          
SEQRES   6 O  137  ASP VAL ALA ALA LYS CYS LYS GLU VAL GLY ILE THR ALA          
SEQRES   7 O  137  VAL HIS ILE LYS ILE ARG ALA THR GLY GLY THR ARG SER          
SEQRES   8 O  137  LYS THR PRO GLY PRO GLY GLY GLN ALA ALA LEU ARG ALA          
SEQRES   9 O  137  LEU ALA ARG SER GLY LEU ARG ILE GLY ARG ILE GLU ASP          
SEQRES  10 O  137  VAL THR PRO VAL PRO SER ASP SER THR ARG LYS LYS GLY          
SEQRES  11 O  137  GLY ARG ARG GLY ARG ARG LEU                                  
SEQRES   1 P  142  MET SER GLU ALA ALA ALA PRO ARG LYS ARG SER PHE LYS          
SEQRES   2 P  142  THR TYR SER TYR LYS GLY VAL ASP LEU GLU LYS LEU LEU          
SEQRES   3 P  142  GLU MET PRO THR GLU ASP PHE VAL LYS LEU ALA PRO ALA          
SEQRES   4 P  142  ARG VAL ARG ARG LYS PHE ALA ARG GLY LEU SER GLU LYS          
SEQRES   5 P  142  PRO ALA GLY LEU MET LYS LYS LEU ARG ALA ALA LYS LEU          
SEQRES   6 P  142  SER ALA PRO GLU ASN GLU LYS PRO ALA VAL VAL ARG THR          
SEQRES   7 P  142  HIS LEU ARG ASN MET ILE ILE VAL PRO GLU MET ILE GLY          
SEQRES   8 P  142  SER VAL VAL GLY VAL TYR ASN GLY LYS VAL PHE ASN GLN          
SEQRES   9 P  142  VAL GLU ILE ARG PRO GLU MET VAL GLY HIS TYR LEU GLY          
SEQRES  10 P  142  GLU PHE SER ILE THR TYR THR PRO VAL ARG HIS GLY ARG          
SEQRES  11 P  142  ALA GLY ALA THR THR SER ARG PHE ILE PRO LEU ARG              
SEQRES   1 Q  143  MET SER THR VAL PRO SER VAL GLN THR PHE GLY LYS LYS          
SEQRES   2 Q  143  LYS SER ALA THR ALA VAL ALA HIS VAL LYS ALA GLY LYS          
SEQRES   3 Q  143  GLY LEU ILE LYS VAL ASN GLY SER PRO ILE THR LEU VAL          
SEQRES   4 Q  143  GLN PRO GLU ILE LEU ARG PHE LYS VAL TYR GLU PRO LEU          
SEQRES   5 Q  143  LEU LEU VAL GLY LEU ASP LYS PHE ALA ASN ILE ASP ILE          
SEQRES   6 Q  143  ARG VAL LYS VAL THR GLY GLY GLY HIS VAL SER GLN VAL          
SEQRES   7 Q  143  TYR ALA ILE ARG GLN ALA ILE ALA LYS GLY LEU VAL ALA          
SEQRES   8 Q  143  TYR HIS GLN LYS PHE VAL ASP GLU GLN SER LYS ASN GLU          
SEQRES   9 Q  143  LEU LYS LYS ALA PHE THR SER TYR ASP ARG THR LEU LEU          
SEQRES  10 Q  143  ILE ALA ASP SER ARG ARG PRO GLU PRO LYS LYS PHE GLY          
SEQRES  11 Q  143  GLY ARG GLY ALA ARG SER ARG PHE GLN LYS SER TYR ARG          
SEQRES   1 R  136  MET GLY ARG VAL ARG THR LYS THR VAL LYS ARG ALA SER          
SEQRES   2 R  136  LYS ALA LEU ILE GLU LYS TYR TYR PRO LYS LEU THR MET          
SEQRES   3 R  136  ASP PHE GLN THR ASN LYS ARG LEU CYS ASP GLU ILE ALA          
SEQRES   4 R  136  THR ILE GLN SER LYS ARG LEU ARG ASN LYS ILE ALA GLY          
SEQRES   5 R  136  TYR THR THR HIS LEU MET LYS ARG ILE GLN LYS GLY PRO          
SEQRES   6 R  136  VAL ARG GLY ILE SER PHE LYS LEU GLN GLU GLU GLU ARG          
SEQRES   7 R  136  GLU ARG LYS ASP GLN TYR VAL PRO ASP VAL SER ALA LEU          
SEQRES   8 R  136  ASP LEU SER HIS SER ASN ASP VAL LEU ASN VAL ASP THR          
SEQRES   9 R  136  GLN THR ALA GLU LEU VAL ASN SER LEU GLY LEU LYS LEU          
SEQRES  10 R  136  PRO LEU SER VAL SER SER VAL SER ALA VAL ARG ASP ARG          
SEQRES  11 R  136  ARG PHE ARG LYS ARG ASN                                      
SEQRES   1 S  146  MET SER LEU VAL VAL GLN GLU GLN GLY SER PHE GLN HIS          
SEQRES   2 S  146  ILE LEU ARG LEU LEU ASN THR ASN VAL ASP GLY ASN ILE          
SEQRES   3 S  146  ASN VAL VAL TYR ALA LEU THR THR ILE ARG GLY VAL GLY          
SEQRES   4 S  146  ARG ARG TYR ALA ASN LEU VAL CYS LYS LYS ALA ASP VAL          
SEQRES   5 S  146  ASP LEU HIS LYS ARG ALA GLY GLU LEU THR GLN GLU GLU          
SEQRES   6 S  146  LEU GLU ARG ILE VAL GLN ILE MET GLN ASN PRO THR HIS          
SEQRES   7 S  146  TYR LYS ILE PRO ALA TRP PHE LEU ASN ARG GLN LYS ASP          
SEQRES   8 S  146  VAL ASN ASP GLY LYS ASP TYR HIS SER LEU ALA ASN ASN          
SEQRES   9 S  146  LEU GLU SER LYS LEU ARG ASP ASP LEU GLU ARG LEU LYS          
SEQRES  10 S  146  LYS ILE ARG SER HIS ARG GLY ILE ARG HIS PHE TRP GLY          
SEQRES  11 S  146  LEU ARG VAL ARG GLY GLN HIS THR LYS THR THR GLY ARG          
SEQRES  12 S  146  ARG ARG ALA                                                  
SEQRES   1 T  144  MET PRO GLY VAL SER VAL ARG ASP VAL PRO ALA GLN ASP          
SEQRES   2 T  144  PHE ILE ASN ASN TYR ALA SER PHE LEU GLN ARG GLN GLY          
SEQRES   3 T  144  LYS LEU GLU VAL PRO GLY TYR VAL ASP ILE VAL LYS THR          
SEQRES   4 T  144  SER ALA GLY ASN GLU LEU PRO PRO GLN ASP SER GLU GLY          
SEQRES   5 T  144  TRP PHE TYR LYS ARG ALA ALA SER VAL ALA ARG HIS ILE          
SEQRES   6 T  144  TYR LEU ARG LYS GLN VAL GLY VAL GLY LYS LEU ASN LYS          
SEQRES   7 T  144  LEU TYR GLY GLY ALA LYS ASN ARG GLY VAL ARG PRO HIS          
SEQRES   8 T  144  LYS HIS VAL ASP ALA SER GLY SER ILE ASN ARG LYS VAL          
SEQRES   9 T  144  LEU GLN SER LEU GLU LYS LEU GLY VAL VAL GLU ILE SER          
SEQRES  10 T  144  PRO LYS GLY GLY ARG ARG ILE SER ASP ASN GLY LEU ARG          
SEQRES  11 T  144  ASP LEU ASP ARG ILE ALA ALA ALA THR LEU GLU ASP GLU          
SEQRES  12 T  144  GLU                                                          
SEQRES   1 U  117  MET SER GLN VAL GLU LYS LYS SER GLU GLN GLN GLN GLU          
SEQRES   2 U  117  VAL VAL ILE HIS LYS ILE ARG ILE ASN LEU THR SER THR          
SEQRES   3 U  117  LYS VAL LYS GLN LEU GLU ASN VAL SER ALA ASN ILE ILE          
SEQRES   4 U  117  LYS ASN ALA GLU THR PHE LYS LEU VAL LYS LYS GLY PRO          
SEQRES   5 U  117  VAL ARG LEU PRO THR LYS VAL LEU LYS ILE SER THR ARG          
SEQRES   6 U  117  LYS THR PRO ASN GLY GLU GLY SER LYS THR TRP ASP THR          
SEQRES   7 U  117  TYR GLU MET ARG ILE HIS LYS ARG TYR ILE ASP LEU GLU          
SEQRES   8 U  117  ALA PRO ALA HIS ILE VAL LYS ARG ILE THR GLN ILE THR          
SEQRES   9 U  117  ILE GLU PRO GLY VAL ASP VAL GLU VAL ILE ILE ALA ALA          
SEQRES   1 V   87  MET GLU ASN ASP LYS GLY GLN LEU VAL GLU LEU TYR VAL          
SEQRES   2 V   87  PRO ARG LYS CYS SER ALA THR ASN ARG ILE ILE LYS ALA          
SEQRES   3 V   87  LYS ASP HIS SER SER VAL GLN ILE ASN ILE ALA GLN VAL          
SEQRES   4 V   87  ASP GLU GLU GLY ARG ALA ILE PRO GLY GLU TYR VAL THR          
SEQRES   5 V   87  TYR ALA LEU SER GLY TYR ILE ARG ALA ARG GLY GLU ALA          
SEQRES   6 V   87  ASP ASP SER LEU ASN ARG LEU ALA GLN GLN ASP GLY LEU          
SEQRES   7 V   87  LEU LYS ASN VAL TRP SER TYR SER ARG                          
SEQRES   1 W  130  MET THR ARG THR SER VAL LEU ALA ASP ALA LEU ASN ALA          
SEQRES   2 W  130  ILE ASN ASN ALA GLU LYS THR GLY LYS ARG GLN VAL LEU          
SEQRES   3 W  130  ILE ARG PRO SER SER LYS VAL ILE ILE LYS PHE LEU GLN          
SEQRES   4 W  130  VAL MET GLN LYS HIS GLY TYR ILE GLY GLU PHE GLU TYR          
SEQRES   5 W  130  ILE ASP ASP HIS ARG SER GLY LYS ILE VAL VAL GLN LEU          
SEQRES   6 W  130  ASN GLY ARG LEU ASN LYS CYS GLY VAL ILE SER PRO ARG          
SEQRES   7 W  130  PHE ASN VAL LYS ILE ALA ASP VAL GLU LYS TRP THR ALA          
SEQRES   8 W  130  ASN LEU LEU PRO ALA ARG GLN PHE GLY TYR VAL ILE LEU          
SEQRES   9 W  130  THR THR SER ALA GLY ILE MET ASP HIS GLU GLU ALA HIS          
SEQRES  10 W  130  ARG LYS HIS VAL SER GLY LYS ILE LEU GLY PHE VAL TYR          
SEQRES   1 X  145  MET GLY LYS GLY LYS PRO ARG GLY LEU ASN SER ALA ARG          
SEQRES   2 X  145  LYS LEU ARG VAL HIS ARG ARG ASN ASN ARG TRP ALA GLU          
SEQRES   3 X  145  THR THR TYR LYS LYS ARG LEU LEU GLY THR ALA PHE LYS          
SEQRES   4 X  145  SER SER PRO PHE GLY GLY SER SER HIS ALA LYS GLY ILE          
SEQRES   5 X  145  VAL LEU GLU LYS ILE GLY ILE GLU SER LYS GLN PRO ASN          
SEQRES   6 X  145  SER ALA ILE ARG LYS CYS VAL ARG VAL GLN LEU ILE LYS          
SEQRES   7 X  145  ASN GLY LYS LYS VAL THR ALA PHE VAL PRO ASN ASP GLY          
SEQRES   8 X  145  CYS LEU ASN PHE VAL ASP GLU ASN ASP GLU VAL LEU LEU          
SEQRES   9 X  145  ALA GLY PHE GLY ARG LYS GLY LYS ALA LYS GLY ASP ILE          
SEQRES  10 X  145  PRO GLY VAL ARG PHE LYS VAL VAL LYS VAL SER GLY VAL          
SEQRES  11 X  145  SER LEU LEU ALA LEU TRP LYS GLU LYS LYS GLU LYS PRO          
SEQRES  12 X  145  ARG SER                                                      
SEQRES   1 Y  135  MET SER ASP ALA ILE THR ILE ARG THR ARG LYS VAL ILE          
SEQRES   2 Y  135  SER ASN PRO LEU LEU ALA ARG LYS GLN PHE VAL VAL ASP          
SEQRES   3 Y  135  VAL LEU HIS PRO ASN ARG ALA ASN VAL SER LYS ASP GLU          
SEQRES   4 Y  135  LEU ARG GLU LYS LEU ALA GLU ALA TYR LYS ALA GLU LYS          
SEQRES   5 Y  135  ASP ALA VAL SER VAL PHE GLY PHE ARG THR GLN TYR GLY          
SEQRES   6 Y  135  GLY GLY LYS SER THR GLY PHE GLY LEU VAL TYR ASN SER          
SEQRES   7 Y  135  VAL ALA ASP ALA LYS LYS PHE GLU PRO ALA TYR ARG LEU          
SEQRES   8 Y  135  VAL ARG TYR GLY LEU ALA GLU LYS VAL GLU LYS ALA SER          
SEQRES   9 Y  135  ARG GLN GLN ARG LYS GLN ARG LYS ASN ARG GLY LYS LYS          
SEQRES  10 Y  135  ILE PHE GLY THR GLY LYS SER ILE ALA LYS LYS ALA ALA          
SEQRES  11 Y  135  ARG ARG ASN ALA ASP                                          
SEQRES   1 Z  108  MET PRO PRO LYS GLN GLN LEU SER LYS ALA ALA LYS ALA          
SEQRES   2 Z  108  ALA ALA ALA MET ALA GLY GLY LYS LYS SER LYS LYS LYS          
SEQRES   3 Z  108  TRP SER LYS LYS SER HIS LYS ASP LYS ALA LYS HIS ALA          
SEQRES   4 Z  108  VAL VAL LEU ASP GLN ASP LYS PHE ASP ARG ILE MET LYS          
SEQRES   5 Z  108  GLU ALA PRO THR TYR ARG TYR VAL SER VAL SER VAL LEU          
SEQRES   6 Z  108  VAL ASP ARG PHE LYS LEU GLY GLY SER LEU ALA ARG VAL          
SEQRES   7 Z  108  ALA LEU ARG HIS LEU GLU ASN GLU GLY ILE ILE LYS PRO          
SEQRES   8 Z  108  VAL SER LYS HIS SER LYS GLN ALA ILE TYR THR ARG ALA          
SEQRES   9 Z  108  THR ALA SER GLU                                              
SEQRES   1 a  119  MET PRO LYS LYS ARG ALA SER ASN GLY ARG ASN LYS LYS          
SEQRES   2 a  119  GLY ARG GLY HIS VAL LYS PRO VAL ARG CYS VAL ASN CYS          
SEQRES   3 a  119  SER ARG SER VAL PRO LYS ASP LYS ALA ILE LYS ARG MET          
SEQRES   4 a  119  ALA ILE ARG ASN ILE VAL GLU ALA ALA ALA ILE ARG ASP          
SEQRES   5 a  119  LEU SER GLU ALA SER VAL TYR ALA GLU TYR ALA LEU PRO          
SEQRES   6 a  119  LYS THR TYR ASN LYS LEU HIS TYR CYS ILE SER CYS ALA          
SEQRES   7 a  119  ILE HIS ALA ARG ILE VAL ARG VAL ARG SER ARG THR ASP          
SEQRES   8 a  119  ARG ARG ILE ARG ALA PRO PRO GLN ARG PRO ARG PHE ASN          
SEQRES   9 a  119  ARG ASP ASN LYS VAL SER PRO ALA ASP ALA ALA LYS LYS          
SEQRES  10 a  119  ALA LEU                                                      
SEQRES   1 b   82  MET VAL LEU VAL GLN ASP LEU LEU HIS PRO THR ALA ALA          
SEQRES   2 b   82  SER GLU ALA ARG LYS HIS LYS LEU LYS THR LEU VAL GLN          
SEQRES   3 b   82  SER PRO ARG SER HIS PHE LEU ASP VAL LYS CYS PRO GLY          
SEQRES   4 b   82  CYS LEU ASN ILE THR THR VAL PHE SER HIS ALA GLN THR          
SEQRES   5 b   82  ALA VAL THR CYS GLU SER CYS SER THR VAL LEU CYS THR          
SEQRES   6 b   82  PRO THR GLY GLY LYS ALA LYS LEU SER GLU GLY THR SER          
SEQRES   7 b   82  PHE ARG ARG LYS                                              
SEQRES   1 c   67  MET ASP THR LYS THR PRO VAL THR LEU ALA LYS VAL ILE          
SEQRES   2 c   67  LYS VAL LEU GLY ARG THR GLY SER ARG GLY GLY VAL THR          
SEQRES   3 c   67  GLN VAL ARG VAL GLU PHE LEU GLU ASP THR THR ARG THR          
SEQRES   4 c   67  ILE VAL ARG ASN VAL LYS GLY PRO VAL ARG GLU GLY ASP          
SEQRES   5 c   67  ILE LEU VAL LEU MET GLU SER GLU ARG GLU ALA ARG ARG          
SEQRES   6 c   67  LEU ARG                                                      
SEQRES   1 d   56  MET ALA HIS GLU ASN VAL TRP TYR SER HIS PRO ARG LYS          
SEQRES   2 d   56  PHE GLY LYS GLY SER ARG GLN CYS ARG ILE SER GLY SER          
SEQRES   3 d   56  HIS SER GLY LEU ILE ARG LYS TYR GLY LEU ASN ILE ASP          
SEQRES   4 d   56  ARG GLN SER PHE ARG GLU LYS ALA ASN ASP ILE GLY PHE          
SEQRES   5 d   56  TYR LYS TYR ARG                                              
SEQRES   1 e   63  MET GLY LYS VAL HIS GLY SER LEU ALA ARG ALA GLY LYS          
SEQRES   2 e   63  VAL LYS SER GLN THR PRO LYS VAL GLU LYS GLN GLU LYS          
SEQRES   3 e   63  PRO LYS GLN PRO LYS GLY ARG ALA TYR LYS ARG LEU LEU          
SEQRES   4 e   63  TYR THR ARG ARG PHE VAL ASN VAL THR LEU THR ASN GLY          
SEQRES   5 e   63  LYS ARG LYS MET ASN PRO SER PRO SER SER GLN                  
SEQRES   1 f  150  MET GLN ILE PHE VAL LYS THR LEU THR GLY LYS THR ILE          
SEQRES   2 f  150  THR LEU GLU VAL GLU SER SER ASP THR ILE ASP ASN VAL          
SEQRES   3 f  150  LYS SER LYS ILE GLN ASP LYS GLU GLY ILE PRO PRO ASP          
SEQRES   4 f  150  GLN GLN ARG LEU ILE PHE ALA GLY LYS GLN LEU GLU ASP          
SEQRES   5 f  150  GLY ARG THR LEU SER ASP TYR ASN ILE GLN LYS GLU SER          
SEQRES   6 f  150  THR LEU HIS LEU VAL LEU ARG LEU ARG GLY GLY GLY LYS          
SEQRES   7 f  150  LYS ARG LYS LYS LYS VAL TYR THR THR PRO LYS LYS ILE          
SEQRES   8 f  150  ARG HIS LYS HIS LYS LYS VAL LYS LEU ALA VAL LEU ASN          
SEQRES   9 f  150  TYR TYR LYS VAL ASP ASP GLU GLY LYS VAL ALA LYS LEU          
SEQRES  10 f  150  ARG LYS GLU CYS PRO ASN CYS GLY PRO GLY ILE PHE LEU          
SEQRES  11 f  150  ALA ASN HIS GLY ASP ARG PHE TYR CYS GLY LYS CYS HIS          
SEQRES  12 f  150  SER THR PHE ALA THR GLN LYS                                  
SEQRES   1 g  326  MET SER SER SER ASN ILE MET LEU VAL LEU ARG GLY THR          
SEQRES   2 g  326  LEU GLU GLY HIS ASN GLY TRP VAL THR SER LEU SER THR          
SEQRES   3 g  326  SER ALA ALA GLN PRO ASN LEU LEU VAL SER GLY SER ARG          
SEQRES   4 g  326  ASP LYS THR LEU ILE SER TRP ARG LEU THR GLU ASN GLU          
SEQRES   5 g  326  GLN GLN PHE GLY VAL PRO VAL ARG SER TYR LYS GLY HIS          
SEQRES   6 g  326  SER HIS ILE VAL GLN ASP VAL VAL VAL SER ALA ASP GLY          
SEQRES   7 g  326  ASN TYR ALA VAL SER ALA SER TRP ASP LYS THR LEU ARG          
SEQRES   8 g  326  LEU TRP ASN LEU ALA THR GLY ASN SER GLU ALA ARG PHE          
SEQRES   9 g  326  VAL GLY HIS THR GLY ASP VAL LEU SER VAL ALA ILE ASP          
SEQRES  10 g  326  ALA ASN SER SER LYS ILE ILE SER ALA SER ARG ASP LYS          
SEQRES  11 g  326  THR ILE ARG VAL TRP ASN THR VAL GLY ASP CYS ALA TYR          
SEQRES  12 g  326  VAL LEU LEU GLY HIS THR ASP TRP VAL THR LYS VAL ARG          
SEQRES  13 g  326  VAL ALA PRO LYS ASN LEU GLU ASP GLY GLU VAL ASP ASP          
SEQRES  14 g  326  GLY ARG ILE THR PHE VAL SER ALA GLY MET ASP LYS ILE          
SEQRES  15 g  326  VAL ARG SER TRP SER LEU ASN GLU ASP SER TYR ARG ILE          
SEQRES  16 g  326  GLU ALA ASP PHE ILE GLY HIS ASN ASN TYR ILE ASN VAL          
SEQRES  17 g  326  VAL GLN PRO SER PRO ASP GLY SER LEU ALA ALA SER ALA          
SEQRES  18 g  326  GLY LYS ASP GLY GLN ILE TYR VAL TRP ASN LEU LYS HIS          
SEQRES  19 g  326  LYS SER ALA PHE MET ASN PHE ASP ALA LYS ASP GLU VAL          
SEQRES  20 g  326  PHE ALA LEU ALA PHE SER PRO SER ARG PHE TRP LEU THR          
SEQRES  21 g  326  ALA ALA THR ALA SER GLY ILE LYS ILE TYR ASP LEU GLU          
SEQRES  22 g  326  ASN GLU VAL LEU ILE ASP GLU LEU LYS PRO GLU PHE ALA          
SEQRES  23 g  326  GLY TYR THR LYS ALA GLN ASP PRO HIS ALA VAL SER LEU          
SEQRES  24 g  326  ALA TRP SER ALA ASP GLY GLN THR LEU PHE ALA GLY TYR          
SEQRES  25 g  326  THR ASP ASN VAL ILE ARG VAL TRP GLN VAL MET THR ALA          
SEQRES  26 g  326  ASN                                                          
SEQRES   1 h   25  MET ARG ALA LYS TRP ARG LYS LYS ARG THR ARG ARG LEU          
SEQRES   2 h   25  LYS ARG LYS ARG ARG LYS VAL ARG ALA ARG SER LYS              
SEQRES   1 i  153  MET GLY LYS LYS ASN THR LYS GLY GLY LYS LYS GLY ARG          
SEQRES   2 i  153  ARG GLY LYS ASN ASP SER ASP GLY PRO LYS ARG GLU LEU          
SEQRES   3 i  153  ILE TYR LYS GLU GLU GLY GLN GLU TYR ALA GLN ILE THR          
SEQRES   4 i  153  LYS MET LEU GLY ASN GLY ARG VAL GLU ALA SER CYS PHE          
SEQRES   5 i  153  ASP GLY ASN LYS ARG MET ALA HIS ILE ARG GLY LYS LEU          
SEQRES   6 i  153  ARG LYS LYS VAL TRP MET GLY GLN GLY ASP ILE ILE LEU          
SEQRES   7 i  153  VAL SER LEU ARG ASP PHE GLN ASP ASP GLN CYS ASP VAL          
SEQRES   8 i  153  VAL HIS LYS TYR ASN LEU ASP GLU ALA ARG THR LEU LYS          
SEQRES   9 i  153  ASN GLN GLY GLU LEU PRO GLU ASN ALA LYS ILE ASN GLU          
SEQRES  10 i  153  THR ASP ASN PHE GLY PHE GLU SER ASP GLU ASP VAL ASN          
SEQRES  11 i  153  PHE GLU PHE GLY ASN ALA ASP GLU ASP ASP GLU GLU GLY          
SEQRES  12 i  153  GLU ASP GLU GLU LEU ASP ILE ASP ASP ILE                      
SEQRES   1 j  304  MET SER THR SER HIS CYS ARG PHE TYR GLU ASN LYS TYR          
SEQRES   2 j  304  PRO GLU ILE ASP ASP ILE VAL MET VAL ASN VAL GLN GLN          
SEQRES   3 j  304  ILE ALA GLU MET GLY ALA TYR VAL LYS LEU LEU GLU TYR          
SEQRES   4 j  304  ASP ASN ILE GLU GLY MET ILE LEU LEU SER GLU LEU SER          
SEQRES   5 j  304  ARG ARG ARG ILE ARG SER ILE GLN LYS LEU ILE ARG VAL          
SEQRES   6 j  304  GLY LYS ASN ASP VAL ALA VAL VAL LEU ARG VAL ASP LYS          
SEQRES   7 j  304  GLU LYS GLY TYR ILE ASP LEU SER LYS ARG ARG VAL SER          
SEQRES   8 j  304  SER GLU ASP ILE ILE LYS CYS GLU GLU LYS TYR GLN LYS          
SEQRES   9 j  304  SER LYS THR VAL HIS SER ILE LEU ARG TYR CYS ALA GLU          
SEQRES  10 j  304  LYS PHE GLN ILE PRO LEU GLU GLU LEU TYR LYS THR ILE          
SEQRES  11 j  304  ALA TRP PRO LEU SER ARG LYS PHE GLY HIS ALA TYR GLU          
SEQRES  12 j  304  ALA PHE LYS LEU SER ILE ILE ASP GLU THR VAL TRP GLU          
SEQRES  13 j  304  GLY ILE GLU PRO PRO SER LYS ASP VAL LEU ASP GLU LEU          
SEQRES  14 j  304  LYS ASN TYR ILE SER LYS ARG LEU THR PRO GLN ALA VAL          
SEQRES  15 j  304  LYS ILE ARG ALA ASP VAL GLU VAL SER CYS PHE SER TYR          
SEQRES  16 j  304  GLU GLY ILE ASP ALA ILE LYS ASP ALA LEU LYS SER ALA          
SEQRES  17 j  304  GLU ASP MET SER THR GLU GLN MET GLN VAL LYS VAL LYS          
SEQRES  18 j  304  LEU VAL ALA ALA PRO LEU TYR VAL LEU THR THR GLN ALA          
SEQRES  19 j  304  LEU ASP LYS GLN LYS GLY ILE GLU GLN LEU GLU SER ALA          
SEQRES  20 j  304  ILE GLU LYS ILE THR GLU VAL ILE THR LYS TYR GLY GLY          
SEQRES  21 j  304  VAL CYS ASN ILE THR MET PRO PRO LYS ALA VAL THR ALA          
SEQRES  22 j  304  THR GLU ASP ALA GLU LEU GLN ALA LEU LEU GLU SER LYS          
SEQRES  23 j  304  GLU LEU ASP ASN ARG SER ASP SER GLU ASP ASP GLU ASP          
SEQRES  24 j  304  GLU SER ASP ASP GLU                                          
SEQRES   1 k  527  MET SER ASP LEU GLN ASP GLN GLU PRO SER ILE ILE ILE          
SEQRES   2 k  527  ASN GLY ASN LEU GLU PRO VAL GLY GLU PRO ASP ILE VAL          
SEQRES   3 k  527  GLU GLU THR GLU VAL VAL ALA GLN GLU THR GLN GLU THR          
SEQRES   4 k  527  GLN ASP ALA ASP LYS PRO LYS LYS LYS VAL ALA PHE THR          
SEQRES   5 k  527  GLY LEU GLU GLU ASP GLY GLU THR GLU GLU GLU LYS ARG          
SEQRES   6 k  527  LYS ARG GLU PHE GLU GLU GLY GLY GLY LEU PRO GLU GLN          
SEQRES   7 k  527  PRO LEU ASN PRO ASP PHE SER LYS LEU ASN PRO LEU SER          
SEQRES   8 k  527  ALA GLU ILE ILE ASN ARG GLN ALA THR ILE ASN ILE GLY          
SEQRES   9 k  527  THR ILE GLY HIS VAL ALA HIS GLY LYS SER THR VAL VAL          
SEQRES  10 k  527  ARG ALA ILE SER GLY VAL GLN THR VAL ARG PHE LYS ASP          
SEQRES  11 k  527  GLU LEU GLU ARG ASN ILE THR ILE LYS LEU GLY TYR ALA          
SEQRES  12 k  527  ASN ALA LYS ILE TYR LYS CYS GLN GLU PRO THR CYS PRO          
SEQRES  13 k  527  GLU PRO ASP CYS TYR ARG SER PHE LYS SER ASP LYS GLU          
SEQRES  14 k  527  ILE SER PRO LYS CYS GLN ARG PRO GLY CYS PRO GLY ARG          
SEQRES  15 k  527  TYR LYS LEU VAL ARG HIS VAL SER PHE VAL ASP CYS PRO          
SEQRES  16 k  527  GLY HIS ASP ILE LEU MET SER THR MET LEU SER GLY ALA          
SEQRES  17 k  527  ALA VAL MET ASP ALA ALA LEU LEU LEU ILE ALA GLY ASN          
SEQRES  18 k  527  GLU SER CYS PRO GLN PRO GLN THR SER GLU HIS LEU ALA          
SEQRES  19 k  527  ALA ILE GLU ILE MET LYS LEU LYS HIS VAL ILE ILE LEU          
SEQRES  20 k  527  GLN ASN LYS VAL ASP LEU MET ARG GLU GLU SER ALA LEU          
SEQRES  21 k  527  GLU HIS GLN LYS SER ILE LEU LYS PHE ILE ARG GLY THR          
SEQRES  22 k  527  ILE ALA ASP GLY ALA PRO ILE VAL PRO ILE SER ALA GLN          
SEQRES  23 k  527  LEU LYS TYR ASN ILE ASP ALA VAL ASN GLU PHE ILE VAL          
SEQRES  24 k  527  LYS THR ILE PRO VAL PRO PRO ARG ASP PHE MET ILE SER          
SEQRES  25 k  527  PRO ARG LEU ILE VAL ILE ARG SER PHE ASP VAL ASN LYS          
SEQRES  26 k  527  PRO GLY ALA GLU ILE GLU ASP LEU LYS GLY GLY VAL ALA          
SEQRES  27 k  527  GLY GLY SER ILE LEU ASN GLY VAL PHE LYS LEU GLY ASP          
SEQRES  28 k  527  GLU ILE GLU ILE ARG PRO GLY ILE VAL THR LYS ASP ASP          
SEQRES  29 k  527  LYS GLY LYS ILE GLN CYS LYS PRO ILE PHE SER ASN ILE          
SEQRES  30 k  527  VAL SER LEU PHE ALA GLU GLN ASN ASP LEU LYS PHE ALA          
SEQRES  31 k  527  VAL PRO GLY GLY LEU ILE GLY VAL GLY THR LYS VAL ASP          
SEQRES  32 k  527  PRO THR LEU CYS ARG ALA ASP ARG LEU VAL GLY GLN VAL          
SEQRES  33 k  527  VAL GLY ALA LYS GLY HIS LEU PRO ASN ILE TYR THR ASP          
SEQRES  34 k  527  ILE GLU ILE ASN TYR PHE LEU LEU ARG ARG LEU LEU GLY          
SEQRES  35 k  527  VAL LYS THR ASP GLY GLN LYS GLN ALA LYS VAL ARG LYS          
SEQRES  36 k  527  LEU GLU PRO ASN GLU VAL LEU MET VAL ASN ILE GLY SER          
SEQRES  37 k  527  THR ALA THR GLY ALA ARG VAL VAL ALA VAL LYS ALA ASP          
SEQRES  38 k  527  MET ALA ARG LEU GLN LEU THR SER PRO ALA CYS THR GLU          
SEQRES  39 k  527  ILE ASN GLU LYS ILE ALA LEU SER ARG ARG ILE GLU LYS          
SEQRES  40 k  527  HIS TRP ARG LEU ILE GLY TRP ALA THR ILE LYS LYS GLY          
SEQRES  41 k  527  THR THR LEU GLU PRO ILE ALA                                  
SEQRES   1 l  285  MET SER SER ASP LEU ALA ALA GLU LEU GLY PHE ASP PRO          
SEQRES   2 l  285  ALA LEU LYS LYS LYS LYS LYS THR LYS LYS VAL ILE PRO          
SEQRES   3 l  285  ASP ASP PHE ASP ALA ALA VAL ASN GLY LYS GLU ASN GLY          
SEQRES   4 l  285  SER GLY ASP ASP LEU PHE ALA GLY LEU LYS LYS LYS LYS          
SEQRES   5 l  285  LYS LYS SER LYS SER VAL SER ALA ASP ALA GLU ALA GLU          
SEQRES   6 l  285  LYS GLU PRO THR ASP ASP ILE ALA GLU ALA LEU GLY GLU          
SEQRES   7 l  285  LEU SER LEU LYS LYS LYS LYS LYS LYS THR LYS ASP SER          
SEQRES   8 l  285  SER VAL ASP ALA PHE GLU LYS GLU LEU ALA LYS ALA GLY          
SEQRES   9 l  285  LEU ASP ASN VAL ASP ALA GLU SER LYS GLU GLY THR PRO          
SEQRES  10 l  285  SER ALA ASN SER SER ILE GLN GLN GLU VAL GLY LEU PRO          
SEQRES  11 l  285  TYR SER GLU LEU LEU SER ARG PHE PHE ASN ILE LEU ARG          
SEQRES  12 l  285  THR ASN ASN PRO GLU LEU ALA GLY ASP ARG SER GLY PRO          
SEQRES  13 l  285  LYS PHE ARG ILE PRO PRO PRO VAL CYS LEU ARG ASP GLY          
SEQRES  14 l  285  LYS LYS THR ILE PHE SER ASN ILE GLN ASP ILE ALA GLU          
SEQRES  15 l  285  LYS LEU HIS ARG SER PRO GLU HIS LEU ILE GLN TYR LEU          
SEQRES  16 l  285  PHE ALA GLU LEU GLY THR SER GLY SER VAL ASP GLY GLN          
SEQRES  17 l  285  LYS ARG LEU VAL ILE LYS GLY LYS PHE GLN SER LYS GLN          
SEQRES  18 l  285  MET GLU ASN VAL LEU ARG ARG TYR ILE LEU GLU TYR VAL          
SEQRES  19 l  285  THR CYS LYS THR CYS LYS SER ILE ASN THR GLU LEU LYS          
SEQRES  20 l  285  ARG GLU GLN SER ASN ARG LEU PHE PHE MET VAL CYS LYS          
SEQRES  21 l  285  SER CYS GLY SER THR ARG SER VAL SER SER ILE LYS THR          
SEQRES  22 l  285  GLY PHE GLN ALA THR VAL GLY LYS ARG ARG ARG MET              
SEQRES   1 m  108  MET SER ILE GLU ASN LEU LYS SER PHE ASP PRO PHE ALA          
SEQRES   2 m  108  ASP THR GLY ASP ASP GLU THR ALA THR SER ASN TYR ILE          
SEQRES   3 m  108  HIS ILE ARG ILE GLN GLN ARG ASN GLY ARG LYS THR LEU          
SEQRES   4 m  108  THR THR VAL GLN GLY VAL PRO GLU GLU TYR ASP LEU LYS          
SEQRES   5 m  108  ARG ILE LEU LYS VAL LEU LYS LYS ASP PHE ALA CYS ASN          
SEQRES   6 m  108  GLY ASN ILE VAL LYS ASP PRO GLU MET GLY GLU ILE ILE          
SEQRES   7 m  108  GLN LEU GLN GLY ASP GLN ARG ALA LYS VAL CYS GLU PHE          
SEQRES   8 m  108  MET ILE SER GLN LEU GLY LEU GLN LYS LYS ASN ILE LYS          
SEQRES   9 m  108  ILE HIS GLY PHE                                              
SEQRES   1 o   92  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   2 o   92  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   3 o   92  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   4 o   92  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   5 o   92  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   6 o   92  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   7 o   92  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   8 o   92  UNK                                                          
SEQRES   1 p   88  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   2 p   88  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   3 p   88  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   4 p   88  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   5 p   88  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   6 p   88  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   7 p   88  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK                      
SEQRES   1 q  347  MET LYS ALA ILE LYS LEU THR GLY HIS GLU ARG PRO LEU          
SEQRES   2 q  347  THR GLN VAL LYS TYR ASN LYS GLU GLY ASP LEU LEU PHE          
SEQRES   3 q  347  SER CYS SER LYS ASP SER SER ALA SER VAL TRP TYR SER          
SEQRES   4 q  347  LEU ASN GLY GLU ARG LEU GLY THR LEU ASP GLY HIS THR          
SEQRES   5 q  347  GLY THR ILE TRP SER ILE ASP VAL ASP CYS PHE THR LYS          
SEQRES   6 q  347  TYR CYS VAL THR GLY SER ALA ASP TYR SER ILE LYS LEU          
SEQRES   7 q  347  TRP ASP VAL SER ASN GLY GLN CYS VAL ALA THR TRP LYS          
SEQRES   8 q  347  SER PRO VAL PRO VAL LYS ARG VAL GLU PHE SER PRO CYS          
SEQRES   9 q  347  GLY ASN TYR PHE LEU ALA ILE LEU ASP ASN VAL MET LYS          
SEQRES  10 q  347  ASN PRO GLY SER ILE ASN ILE TYR GLU ILE GLU ARG ASP          
SEQRES  11 q  347  SER ALA THR HIS GLU LEU THR LYS VAL SER GLU GLU PRO          
SEQRES  12 q  347  ILE HIS LYS ILE ILE THR HIS GLU GLY LEU ASP ALA ALA          
SEQRES  13 q  347  THR VAL ALA GLY TRP SER THR LYS GLY LYS TYR ILE ILE          
SEQRES  14 q  347  ALA GLY HIS LYS ASP GLY LYS ILE SER LYS TYR ASP VAL          
SEQRES  15 q  347  SER ASN ASN TYR GLU TYR VAL ASP SER ILE ASP LEU HIS          
SEQRES  16 q  347  GLU LYS SER ILE SER ASP MET GLN PHE SER PRO ASP LEU          
SEQRES  17 q  347  THR TYR PHE ILE THR SER SER ARG ASP THR ASN SER PHE          
SEQRES  18 q  347  LEU VAL ASP VAL SER THR LEU GLN VAL LEU LYS LYS TYR          
SEQRES  19 q  347  GLU THR ASP CYS PRO LEU ASN THR ALA VAL ILE THR PRO          
SEQRES  20 q  347  LEU LYS GLU PHE ILE ILE LEU GLY GLY GLY GLN GLU ALA          
SEQRES  21 q  347  LYS ASP VAL THR THR THR SER ALA ASN GLU GLY LYS PHE          
SEQRES  22 q  347  GLU ALA ARG PHE TYR HIS LYS ILE PHE GLU GLU GLU ILE          
SEQRES  23 q  347  GLY ARG VAL GLN GLY HIS PHE GLY PRO LEU ASN THR VAL          
SEQRES  24 q  347  ALA ILE SER PRO GLN GLY THR SER TYR ALA SER GLY GLY          
SEQRES  25 q  347  GLU ASP GLY PHE ILE ARG LEU HIS HIS PHE GLU LYS SER          
SEQRES  26 q  347  TYR PHE ASP PHE LYS TYR ASP VAL GLU LYS ALA ALA GLU          
SEQRES  27 q  347  ALA LYS GLU HIS MET GLN GLU ALA ASN                          
SEQRES   1 r   34  LEU HIS GLN ARG GLU LEU LEU LYS GLN TRP THR GLU TYR          
SEQRES   2 r   34  ARG GLU LYS ILE GLY GLN GLU MET GLU LYS SER MET ASN          
SEQRES   3 r   34  PHE LYS ILE PHE ASP VAL GLN PRO                              
SEQRES   1 s   52  VAL HIS LYS SER VAL ALA GLU ARG LYS ASN TRP HIS LYS          
SEQRES   2 s   52  TYR GLY SER GLU LYS GLY SER PRO ALA GLY PRO SER ALA          
SEQRES   3 s   52  VAL THR ALA ARG LEU GLY GLU GLU VAL GLU LEU ARG LEU          
SEQRES   4 s   52  SER ARG ASN TRP LYS GLN ALA GLU GLU GLU ARG ILE GLN          
MODRES 3JAQ 1MG 1    9    G  1N-METHYLGUANOSINE-5'-MONOPHOSPHATE                
MODRES 3JAQ 2MG 1   10    G  2N-METHYLGUANOSINE-5'-MONOPHOSPHATE                
MODRES 3JAQ H2U 1   16    U  5,6-DIHYDROURIDINE-5'-MONOPHOSPHATE                
MODRES 3JAQ M2G 1   26    G  N2-DIMETHYLGUANOSINE-5'-MONOPHOSPHATE              
MODRES 3JAQ T6A 1   37    A                                                     
MODRES 3JAQ 7MG 1   46    G                                                     
MODRES 3JAQ H2U 1   47    U  5,6-DIHYDROURIDINE-5'-MONOPHOSPHATE                
MODRES 3JAQ 5MC 1   48    C  5-METHYLCYTIDINE-5'-MONOPHOSPHATE                  
MODRES 3JAQ 5MC 1   49    C  5-METHYLCYTIDINE-5'-MONOPHOSPHATE                  
MODRES 3JAQ 1MA 1   58    A                                                     
MODRES 3JAQ RIA 1   64    A                                                     
HET    1MG  1   9      24                                                       
HET    2MG  1  10      24                                                       
HET    H2U  1  16      20                                                       
HET    M2G  1  26      25                                                       
HET    T6A  1  37      32                                                       
HET    7MG  1  46      24                                                       
HET    H2U  1  47      20                                                       
HET    5MC  1  48      21                                                       
HET    5MC  1  49      21                                                       
HET    1MA  1  58      23                                                       
HET    RIA  1  64      35                                                       
HET     MG  21801       1                                                       
HET     MG  21802       1                                                       
HET     MG  21803       1                                                       
HET     MG  21804       1                                                       
HET     MG  21805       1                                                       
HET     MG  21806       1                                                       
HET     MG  21807       1                                                       
HET     MG  21808       1                                                       
HET     MG  21809       1                                                       
HET     MG  21810       1                                                       
HET     MG  21811       1                                                       
HET     MG  21812       1                                                       
HET     MG  21813       1                                                       
HET     MG  21814       1                                                       
HET     MG  21815       1                                                       
HET     MG  21816       1                                                       
HET     MG  21817       1                                                       
HET     MG  21818       1                                                       
HET     MG  21819       1                                                       
HET     MG  21820       1                                                       
HET     MG  21821       1                                                       
HET     MG  21822       1                                                       
HET     MG  21823       1                                                       
HET     MG  21824       1                                                       
HET     MG  21825       1                                                       
HET     MG  21826       1                                                       
HET     MG  21827       1                                                       
HET     MG  21828       1                                                       
HET     MG  21829       1                                                       
HET     MG  21830       1                                                       
HET     MG  21831       1                                                       
HET     MG  21832       1                                                       
HET     MG  21833       1                                                       
HET     MG  21834       1                                                       
HET     MG  21835       1                                                       
HET     MG  21836       1                                                       
HET     MG  21837       1                                                       
HET     MG  21838       1                                                       
HET     MG  21839       1                                                       
HET     MG  21840       1                                                       
HET     MG  21841       1                                                       
HET     MG  21842       1                                                       
HET     MG  21843       1                                                       
HET     MG  21844       1                                                       
HET     MG  21845       1                                                       
HET     MG  21846       1                                                       
HET     MG  21847       1                                                       
HET     MG  21848       1                                                       
HET     MG  21849       1                                                       
HET     MG  21850       1                                                       
HET     MG  21851       1                                                       
HET     MG  21852       1                                                       
HET     MG  21853       1                                                       
HET     MG  21854       1                                                       
HET     MG  21855       1                                                       
HET     MG  21856       1                                                       
HET     MG  21857       1                                                       
HET     MG  21858       1                                                       
HET     MG  21859       1                                                       
HET     MG  21860       1                                                       
HET     MG  21861       1                                                       
HET     MG  21862       1                                                       
HET     MG  21863       1                                                       
HET     MG  21864       1                                                       
HET     MG  21865       1                                                       
HET     MG  21866       1                                                       
HET     MG  21867       1                                                       
HET     MG  21868       1                                                       
HET     MG  21869       1                                                       
HET     MG  21870       1                                                       
HET     MG  21871       1                                                       
HET     MG  21872       1                                                       
HET     MG  21873       1                                                       
HET     MG  21874       1                                                       
HET     MG  21875       1                                                       
HET     MG  21876       1                                                       
HET     MG  21877       1                                                       
HET     MG  21878       1                                                       
HET     MG  21879       1                                                       
HET     MG  C 301       1                                                       
HET     MG  Q 201       1                                                       
HET     ZN  a 500       1                                                       
HET     ZN  b 101       1                                                       
HET     ZN  f 501       1                                                       
HET    MET  k 601       8                                                       
HET     MG  k 602       1                                                       
HET    GCP  k 603      32                                                       
HET     ZN  l 301       1                                                       
HETNAM     1MG 1N-METHYLGUANOSINE-5'-MONOPHOSPHATE                              
HETNAM     2MG 2N-METHYLGUANOSINE-5'-MONOPHOSPHATE                              
HETNAM     H2U 5,6-DIHYDROURIDINE-5'-MONOPHOSPHATE                              
HETNAM     M2G N2-DIMETHYLGUANOSINE-5'-MONOPHOSPHATE                            
HETNAM     T6A N-[N-(9-B-D-RIBOFURANOSYLPURIN-6-YL)                             
HETNAM   2 T6A  CARBAMOYL]THREONINE-5'-MONOPHOSPHATE                            
HETNAM     7MG 7N-METHYL-8-HYDROGUANOSINE-5'-MONOPHOSPHATE                      
HETNAM     5MC 5-METHYLCYTIDINE-5'-MONOPHOSPHATE                                
HETNAM     1MA 6-HYDRO-1-METHYLADENOSINE-5'-MONOPHOSPHATE                       
HETNAM     RIA 2'-O-[(5'-PHOSPHO)RIBOSYL]ADENOSINE-5'-MONOPHOSPHATE             
HETNAM      MG MAGNESIUM ION                                                    
HETNAM      ZN ZINC ION                                                         
HETNAM     MET METHIONINE                                                       
HETNAM     GCP PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER                     
HETSYN     T6A N-(NEBULARIN-6-YLCARBAMOYL)-L-THREONINE-5'-                      
HETSYN   2 T6A  MONOPHOSPHATE                                                   
FORMUL   1  1MG    C11 H16 N5 O8 P                                              
FORMUL   1  2MG    C11 H16 N5 O8 P                                              
FORMUL   1  H2U    2(C9 H15 N2 O9 P)                                            
FORMUL   1  M2G    C12 H18 N5 O8 P                                              
FORMUL   1  T6A    C15 H21 N6 O11 P                                             
FORMUL   1  7MG    C11 H18 N5 O8 P                                              
FORMUL   1  5MC    2(C10 H16 N3 O8 P)                                           
FORMUL   1  1MA    C11 H16 N5 O7 P                                              
FORMUL   1  RIA    C15 H23 N5 O14 P2                                            
FORMUL  48   MG    82(MG 2+)                                                    
FORMUL  29   ZN    4(ZN 2+)                                                     
FORMUL  32  MET    C5 H11 N O2 S                                                
FORMUL  34  GCP    C11 H18 N5 O13 P3                                            
HELIX    1   1 THR A   10  ALA A   20  1                                  11    
HELIX    2   2 ASN A   49  ILE A   67  1                                  19    
HELIX    3   3 ASN A   69  GLU A   71  5                                   3    
HELIX    4   4 ARG A   79  TYR A   81  5                                   3    
HELIX    5   5 GLY A   82  THR A   93  1                                  12    
HELIX    6   6 ASP A  129  SER A  137  1                                   9    
HELIX    7   7 LYS A  167  ARG A  185  1                                  19    
HELIX    8   8 ASP B   22  THR B   25  5                                   4    
HELIX    9   9 ASN B   56  LYS B   62  1                                   7    
HELIX   10  10 LEU B   70  GLY B   75  1                                   6    
HELIX   11  11 SER B   76  SER B   80  5                                   5    
HELIX   12  12 THR B  106  VAL B  114  1                                   9    
HELIX   13  13 GLN B  157  VAL B  176  1                                  20    
HELIX   14  14 THR B  180  ILE B  189  1                                  10    
HELIX   15  15 GLU B  191  THR B  201  1                                  11    
HELIX   16  16 ASP B  224  SER B  230  1                                   7    
HELIX   17  17 THR C   44  GLY C   53  1                                  10    
HELIX   18  18 SER C   57  SER C   65  1                                   9    
HELIX   19  19 PHE C   71  LEU C   78  1                                   8    
HELIX   20  20 GLU C  125  SER C  140  1                                  16    
HELIX   21  21 SER C  186  GLY C  197  1                                  12    
HELIX   22  22 THR C  211  ASN C  225  1                                  15    
HELIX   23  23 SER C  243  TYR C  248  1                                   6    
HELIX   24  24 SER D    6  LEU D   29  1                                  24    
HELIX   25  25 VAL D   55  GLY D   60  1                                   6    
HELIX   26  26 ARG D   64  PHE D   77  1                                  14    
HELIX   27  27 SER D   97  GLY D  112  1                                  16    
HELIX   28  28 ALA D  114  GLY D  130  1                                  17    
HELIX   29  29 ASP D  191  THR D  196  1                                   6    
HELIX   30  30 PRO E   15  MET E   19  5                                   5    
HELIX   31  31 LEU E   44  ASN E   50  1                                   7    
HELIX   32  32 ASN E   57  GLN E   67  1                                  11    
HELIX   33  33 THR E  115  SER E  120  1                                   6    
HELIX   34  34 THR E  247  GLN E  258  1                                  12    
HELIX   35  35 PRO F   32  GLN F   37  1                                   6    
HELIX   36  36 PRO F   90  MET F  100  1                                  11    
HELIX   37  37 ASN F  102  ASN F  106  5                                   5    
HELIX   38  38 LYS F  108  LEU F  126  1                                  19    
HELIX   39  39 ASN F  130  GLY F  143  1                                  14    
HELIX   40  40 SER F  165  PHE F  186  1                                  22    
HELIX   41  41 THR F  191  LYS F  205  1                                  15    
HELIX   42  42 SER F  210  ASN F  226  1                                  17    
HELIX   43  43 VAL G   24  TYR G   28  5                                   5    
HELIX   44  44 ARG G  137  GLY G  146  1                                  10    
HELIX   45  45 THR G  180  LYS G  220  1                                  41    
HELIX   46  46 GLN H    5  LEU H    9  5                                   5    
HELIX   47  47 GLU H   15  GLU H   28  1                                  14    
HELIX   48  48 ASN H   29  LYS H   35  5                                   7    
HELIX   49  49 SER H   66  PHE H   85  1                                  20    
HELIX   50  50 THR H  117  VAL H  130  1                                  14    
HELIX   51  51 LYS H  165  THR H  177  1                                  13    
HELIX   52  52 ARG I   25  LEU I   29  5                                   5    
HELIX   53  53 ASN I   88  THR I   93  1                                   6    
HELIX   54  54 THR I  107  TYR I  117  1                                  11    
HELIX   55  55 SER I  137  ALA I  148  1                                  12    
HELIX   56  56 GLU I  154  GLY I  164  1                                  11    
HELIX   57  57 GLY I  187  LYS I  201  1                                  15    
HELIX   58  58 GLU J   20  TYR J   34  1                                  15    
HELIX   59  59 LYS J   39  ARG J   62  1                                  24    
HELIX   60  60 ASP J   66  GLY J   84  1                                  19    
HELIX   61  61 ASP J   94  LEU J   99  5                                   6    
HELIX   62  62 LYS J  100  ARG J  107  1                                   8    
HELIX   63  63 ARG J  108  LYS J  115  1                                   8    
HELIX   64  64 SER J  121  GLN J  131  1                                  11    
HELIX   65  65 ARG J  149  ILE J  156  5                                   8    
HELIX   66  66 ARG J  171  ALA J  180  1                                  10    
HELIX   67  67 PRO K    4  GLY K   19  1                                  16    
HELIX   68  68 LYS K   38  SER K   51  1                                  14    
HELIX   69  69 PHE K   59  TYR K   63  5                                   5    
HELIX   70  70 THR K   69  ASN K   81  1                                  13    
HELIX   71  71 PRO L   45  GLY L   51  1                                   7    
HELIX   72  72 LEU M   21  ASP M   32  1                                  12    
HELIX   73  73 LEU M   38  ARG M   47  1                                  10    
HELIX   74  74 GLU M   62  GLU M   74  1                                  13    
HELIX   75  75 ALA M   85  GLY M   93  1                                   9    
HELIX   76  76 GLU M  125  SER M  132  1                                   8    
HELIX   77  77 SER N   29  GLY N   44  1                                  16    
HELIX   78  78 THR N   46  ALA N   57  1                                  12    
HELIX   79  79 GLN N   62  THR N   67  1                                   6    
HELIX   80  80 LYS N   70  GLY N   79  1                                  10    
HELIX   81  81 PRO N   85  ASN N  105  1                                  21    
HELIX   82  82 LYS N  109  VAL N  132  1                                  24    
HELIX   83  83 SER N  143  ASN N  151  1                                   9    
HELIX   84  84 ASP O   51  SER O   55  5                                   5    
HELIX   85  85 SER O   56  GLY O   75  1                                  20    
HELIX   86  86 GLY O   97  ARG O  107  1                                  11    
HELIX   87  87 ASP P   21  LEU P   26  5                                   6    
HELIX   88  88 PRO P   29  LEU P   36  1                                   8    
HELIX   89  89 PRO P   38  ARG P   47  1                                  10    
HELIX   90  90 GLY P   55  ALA P   67  1                                  13    
HELIX   91  91 TYR P  115  SER P  120  1                                   6    
HELIX   92  92 ARG Q   45  GLY Q   56  1                                  12    
HELIX   93  93 LEU Q   57  ALA Q   61  5                                   5    
HELIX   94  94 HIS Q   74  PHE Q   96  1                                  23    
HELIX   95  95 ASP Q   98  THR Q  110  1                                  13    
HELIX   96  96 THR R    6  TYR R   20  1                                  15    
HELIX   97  97 ASP R   27  ALA R   39  1                                  13    
HELIX   98  98 SER R   43  GLN R   62  1                                  20    
HELIX   99  99 GLN R   74  ARG R   78  1                                   5    
HELIX  100 100 GLN R   83  SER R   89  1                                   7    
HELIX  101 101 THR R  104  GLY R  114  1                                  11    
HELIX  102 102 VAL S   28  THR S   33  1                                   6    
HELIX  103 103 ARG S   40  ALA S   50  1                                  11    
HELIX  104 104 THR S   62  ASN S   75  1                                  14    
HELIX  105 105 ASN S  104  ILE S  119  1                                  16    
HELIX  106 106 SER S  121  GLY S  130  1                                  10    
HELIX  107 107 PRO T   10  GLN T   25  1                                  16    
HELIX  108 108 TRP T   53  ARG T   68  1                                  16    
HELIX  109 109 GLY T   72  TYR T   80  1                                   9    
HELIX  110 110 SER T   99  LEU T  111  1                                  13    
HELIX  111 111 SER T  125  GLU T  144  1                                  20    
HELIX  112 112 LYS U   30  LYS U   49  1                                  20    
HELIX  113 113 ALA U   97  ILE U  106  1                                  10    
HELIX  114 114 SER V   56  GLY V   63  1                                   8    
HELIX  115 115 GLU V   64  ASP V   76  1                                  13    
HELIX  116 116 SER W    5  GLY W   21  1                                  17    
HELIX  117 117 SER W   31  HIS W   44  1                                  14    
HELIX  118 118 ILE W   83  LEU W   94  1                                  12    
HELIX  119 119 ASP W  112  HIS W  120  1                                   9    
HELIX  120 120 SER X   11  ARG X   23  1                                  13    
HELIX  121 121 GLU X   26  GLY X   35  1                                  10    
HELIX  122 122 GLY X   35  SER X   40  1                                   6    
HELIX  123 123 ASP X   90  VAL X   96  5                                   7    
HELIX  124 124 LEU X  132  LYS X  137  1                                   6    
HELIX  125 125 SER Y   36  GLU Y   46  1                                  11    
HELIX  126 126 SER Y   78  GLU Y   86  1                                   9    
HELIX  127 127 PRO Y   87  GLY Y   95  1                                   9    
HELIX  128 128 SER Y  104  ILE Y  118  1                                  15    
HELIX  129 129 GLY Y  122  ASN Y  133  1                                  12    
HELIX  130 130 ASP Z   43  ALA Z   54  1                                  12    
HELIX  131 131 VAL Z   62  ARG Z   68  1                                   7    
HELIX  132 132 SER Z   74  HIS Z   82  1                                   9    
HELIX  133 133 ALA a   49  SER a   57  1                                   9    
HELIX  134 134 THR b   11  LYS b   18  1                                   8    
HELIX  135 135 ARG d   40  GLY d   51  1                                  12    
HELIX  136 136 GLY e   32  PHE e   44  1                                  13    
HELIX  137 137 THR g  289  ASP g  293  5                                   5    
HELIX  138 138 ARG h    2  LYS h   25  1                                  24    
HELIX  139 139 ASN i   96  GLY i  107  1                                  12    
HELIX  140 140 ASP j   94  GLU j  117  1                                  24    
HELIX  141 141 PRO j  122  ILE j  130  1                                   9    
HELIX  142 142 ILE j  130  GLY j  139  1                                  10    
HELIX  143 143 HIS j  140  ILE j  149  1                                  10    
HELIX  144 144 SER j  162  SER j  174  1                                  13    
HELIX  145 145 GLY j  197  GLU j  209  1                                  13    
HELIX  146 146 GLN j  238  GLY j  259  1                                  22    
HELIX  147 147 LYS k  113  SER k  121  1                                   9    
HELIX  148 148 MET k  201  ALA k  208  1                                   8    
HELIX  149 149 GLN k  226  MET k  239  1                                  14    
HELIX  150 150 GLU k  257  LYS k  268  1                                  12    
HELIX  151 151 ASN k  290  ILE k  302  1                                  13    
HELIX  152 152 TYR l  131  LEU l  142  1                                  12    
HELIX  153 153 ASN l  176  LEU l  184  1                                   9    
HELIX  154 154 SER l  187  LEU l  199  1                                  13    
HELIX  155 155 GLN l  218  TYR l  233  1                                  16    
HELIX  156 156 ASP m   50  ALA m   63  1                                  14    
HELIX  157 157 GLN m   84  GLN m   95  1                                  12    
HELIX  158 158 UNK o  754  UNK o  769  1                                  16    
HELIX  159 159 UNK o  773  UNK o  785  1                                  13    
HELIX  160 160 UNK o  789  UNK o  802  1                                  14    
HELIX  161 161 UNK o  807  UNK o  818  1                                  12    
HELIX  162 162 UNK o  830  UNK o  834  1                                   5    
HELIX  163 163 UNK o  838  UNK o  846  1                                   9    
HELIX  164 164 UNK o  851  UNK o  866  1                                  16    
HELIX  165 165 UNK p   21  UNK p   32  1                                  12    
HELIX  166 166 UNK p  117  UNK p  135  1                                  19    
HELIX  167 167 UNK p  140  UNK p  148  1                                   9    
HELIX  168 168 UNK p  151  UNK p  158  1                                   8    
HELIX  169 169 UNK p  171  UNK p  185  1                                  15    
HELIX  170 170 UNK p  194  UNK p  206  1                                  13    
HELIX  171 171 UNK p  212  UNK p  216  1                                   5    
HELIX  172 172 GLU q  323  PHE q  329  1                                   7    
HELIX  173 173 TYR q  331  GLU q  341  1                                  11    
HELIX  174 174 HIS r  705  SER r  727  1                                  23    
HELIX  175 175 LYS s   47  ASN s   54  1                                   8    
HELIX  176 176 TRP s   87  GLN s   96  1                                  10    
SHEET    1   A 2 VAL A  37  ALA A  40  0                                        
SHEET    2   A 2 ASN A  46  ILE A  48 -1  O  VAL A  47   N  TYR A  38           
SHEET    1   B 5 THR A  96  ALA A  99  0                                        
SHEET    2   B 5 VAL A  73  SER A  77  1  N  SER A  77   O  ILE A  98           
SHEET    3   B 5 LEU A 120  VAL A 123  1  O  ILE A 122   N  ILE A  76           
SHEET    4   B 5 VAL A 143  THR A 147  1  O  ILE A 144   N  VAL A 121           
SHEET    5   B 5 ILE A 160  PRO A 161  1  O  ILE A 160   N  ALA A 145           
SHEET    1   C 6 ASN B  42  ASN B  49  0                                        
SHEET    2   C 6 LYS B  27  LYS B  33 -1  N  GLU B  28   O  VAL B  48           
SHEET    3   C 6 ASN B  95  PHE B 105  1  O  LEU B  96   N  LYS B  33           
SHEET    4   C 6 VAL B 215  LYS B 219 -1  O  VAL B 215   N  MET B 103           
SHEET    5   C 6 VAL B 134  PHE B 142 -1  N  VAL B 134   O  LEU B 218           
SHEET    6   C 6 LEU B 120  LYS B 128 -1  N  VAL B 127   O  LEU B 135           
SHEET    1   D 6 VAL B  65  CYS B  69  0                                        
SHEET    2   D 6 ARG B  82  VAL B  91 -1  O  LEU B  86   N  VAL B  66           
SHEET    3   D 6 ASN B  95  PHE B 105 -1  O  ASP B 104   N  LYS B  83           
SHEET    4   D 6 VAL B 215  LYS B 219 -1  O  VAL B 215   N  MET B 103           
SHEET    5   D 6 VAL B 134  PHE B 142 -1  N  VAL B 134   O  LEU B 218           
SHEET    6   D 6 GLN B 208  HIS B 211 -1  O  HIS B 211   N  ILE B 140           
SHEET    1   E 4 LYS C  82  PRO C  90  0                                        
SHEET    2   E 4 PHE C 103  GLY C 110 -1  O  VAL C 108   N  GLU C  84           
SHEET    3   E 4 HIS C 115  ALA C 123 -1  O  GLY C 117   N  VAL C 109           
SHEET    4   E 4 VAL C 141  PRO C 143 -1  O  ILE C 142   N  VAL C 116           
SHEET    1   F 2 ARG C 146  GLY C 147  0                                        
SHEET    2   F 2 SER C 158  LEU C 159 -1  O  SER C 158   N  GLY C 147           
SHEET    1   G 4 THR C 163  CYS C 167  0                                        
SHEET    2   G 4 VAL C 170  PRO C 176 -1  O  LEU C 174   N  THR C 163           
SHEET    3   G 4 VAL C 201  THR C 206 -1  O  TYR C 202   N  ILE C 175           
SHEET    4   G 4 ILE C 183  VAL C 184  1  N  VAL C 184   O  VAL C 201           
SHEET    1   H 3 TYR D  34  VAL D  41  0                                        
SHEET    2   H 3 THR D  46  ALA D  52 -1  O  ILE D  49   N  GLU D  38           
SHEET    3   H 3 ILE D  84  ARG D  90  1  O  TYR D  87   N  ILE D  50           
SHEET    1   I 4 ALA D 147  ASP D 154  0                                        
SHEET    2   I 4 CYS D 134  LYS D 141 -1  N  CYS D 134   O  ASP D 154           
SHEET    3   I 4 VAL D 181  MET D 189 -1  O  LYS D 185   N  VAL D 137           
SHEET    4   I 4 ILE D 168  LEU D 176 -1  N  VAL D 175   O  LEU D 182           
SHEET    1   J 2 LEU E  42  PRO E  43  0                                        
SHEET    2   J 2 PRO E  83  ALA E  84 -1  O  ALA E  84   N  LEU E  42           
SHEET    1   K 4 VAL E  70  VAL E  72  0                                        
SHEET    2   K 4 VAL E  89  LEU E  92 -1  O  THR E  91   N  LYS E  71           
SHEET    3   K 4 ASN E  98  ARG E 100 -1  O  PHE E  99   N  ILE E  90           
SHEET    4   K 4 ARG E 113  ILE E 114 -1  O  ILE E 114   N  ASN E  98           
SHEET    1   L 5 THR E 146  ARG E 148  0                                        
SHEET    2   L 5 ILE E 136  THR E 141 -1  N  VAL E 139   O  ILE E 147           
SHEET    3   L 5 LYS E 122  GLY E 132 -1  N  LYS E 128   O  VAL E 140           
SHEET    4   L 5 THR E 159  VAL E 162 -1  O  VAL E 162   N  LYS E 122           
SHEET    5   L 5 ILE E 169  ILE E 173 -1  O  ILE E 173   N  THR E 159           
SHEET    1   M 3 ARG E 191  GLY E 193  0                                        
SHEET    2   M 3 VAL E 181  VAL E 183 -1  N  VAL E 181   O  GLY E 193           
SHEET    3   M 3 VAL E 225  VAL E 227 -1  O  PHE E 226   N  TYR E 182           
SHEET    1   N 3 HIS E 197  ARG E 198  0                                        
SHEET    2   N 3 LEU E 207  ILE E 210 -1  O  HIS E 209   N  HIS E 197           
SHEET    3   N 3 PHE E 218  ARG E 221 -1  O  THR E 220   N  VAL E 208           
SHEET    1   O 2 GLY E 229  GLU E 230  0                                        
SHEET    2   O 2 ARG E 233  PRO E 234 -1  O  ARG E 233   N  GLU E 230           
SHEET    1   P 6 ASP F 147  ARG F 150  0                                        
SHEET    2   P 6 ARG F 159  VAL F 164 -1  O  VAL F 162   N  ASP F 147           
SHEET    3   P 6 ILE c  40  LYS c  45  1  O  LYS c  45   N  ASP F 163           
SHEET    4   P 6 VAL c  25  PHE c  32 -1  N  THR c  26   O  VAL c  44           
SHEET    5   P 6 THR c   8  THR c  19 -1  N  LYS c  11   O  GLU c  31           
SHEET    6   P 6 ILE c  53  LEU c  56 -1  O  LEU c  54   N  ALA c  10           
SHEET    1   Q 5 THR G  12  GLU G  17  0                                        
SHEET    2   Q 5 LYS G   2  TYR G   7 -1  N  ILE G   5   O  LYS G  14           
SHEET    3   Q 5 LEU G 106  LYS G 115  1  O  LEU G 111   N  ASN G   4           
SHEET    4   Q 5 VAL G  49  ASP G  57 -1  N  LYS G  51   O  ILE G 112           
SHEET    5   Q 5 GLN G  34  ASP G  37 -1  N  VAL G  36   O  PHE G  50           
SHEET    1   R 5 THR G  12  GLU G  17  0                                        
SHEET    2   R 5 LYS G   2  TYR G   7 -1  N  ILE G   5   O  LYS G  14           
SHEET    3   R 5 LEU G 106  LYS G 115  1  O  LEU G 111   N  ASN G   4           
SHEET    4   R 5 VAL G  49  ASP G  57 -1  N  LYS G  51   O  ILE G 112           
SHEET    5   R 5 PHE G  61  PRO G  62 -1  O  PHE G  61   N  ASP G  57           
SHEET    1   S 2 ARG G  72  LEU G  77  0                                        
SHEET    2   S 2 LYS G  93  ARG G  98 -1  O  VAL G  97   N  VAL G  73           
SHEET    1   T 2 ARG G 160  THR G 163  0                                        
SHEET    2   T 2 SER G 168  LYS G 171 -1  O  TYR G 169   N  VAL G 162           
SHEET    1   U 3 ILE H  46  GLU H  50  0                                        
SHEET    2   U 3 LYS H  56  VAL H  62 -1  O  ALA H  57   N  ILE H  49           
SHEET    3   U 3 VAL H  90  ALA H  94  1  O  LEU H  93   N  VAL H  60           
SHEET    1   V 6 GLN H 180  GLU H 184  0                                        
SHEET    2   V 6 LYS H 148  LEU H 154  1  N  GLN H 150   O  GLN H 180           
SHEET    3   V 6 ILE H 135  TYR H 142 -1  N  ARG H 139   O  LYS H 151           
SHEET    4   V 6 PHE W  50  ASP W  54 -1  O  ASP W  54   N  LYS H 138           
SHEET    5   V 6 LYS W  60  GLN W  64 -1  O  LYS W  60   N  ILE W  53           
SHEET    6   V 6 GLN W  24  ILE W  27 -1  N  VAL W  25   O  VAL W  63           
SHEET    1   W 2 HIS I  44  ARG I  47  0                                        
SHEET    2   W 2 GLN I  53  ARG I  56 -1  O  ARG I  56   N  HIS I  44           
SHEET    1   X 6 THR I  62  TRP I  67  0                                        
SHEET    2   X 6 VAL I  72  TYR I  83 -1  O  VAL I  72   N  TRP I  67           
SHEET    3   X 6 ILE I 101  ILE I 104 -1  O  ILE I 101   N  TYR I  83           
SHEET    4   X 6 LEU I 166  ILE I 170 -1  O  ALA I 168   N  VAL I 102           
SHEET    5   X 6 ASP I 181  ILE I 184 -1  O  TYR I 183   N  ALA I 169           
SHEET    6   X 6 THR I  62  TRP I  67  1  N  SER I  66   O  ILE I 184           
SHEET    1   Y 2 VAL K  55  GLN K  58  0                                        
SHEET    2   Y 2 TYR K  65  LEU K  68 -1  O  THR K  67   N  LYS K  56           
SHEET    1   Z 6 ILE L  70  SER L  77  0                                        
SHEET    2   Z 6 THR L  83  ARG L  87 -1  O  ARG L  87   N  THR L  74           
SHEET    3   Z 6 ASN L 106  HIS L 110 -1  O  ALA L 109   N  ILE L  84           
SHEET    4   Z 6 PHE L 137  VAL L 142  1  O  PHE L 137   N  HIS L 110           
SHEET    5   Z 6 ILE L 122  GLN L 127 -1  N  GLY L 126   O  ASN L 138           
SHEET    6   Z 6 ILE L  70  SER L  77 -1  N  LEU L  71   O  VAL L 125           
SHEET    1  AA 2 TYR L  90  VAL L  94  0                                        
SHEET    2  AA 2 ARG L  99  ARG L 103 -1  O  ARG L  99   N  VAL L  94           
SHEET    1  AB 3 LEU M  34  GLY M  37  0                                        
SHEET    2  AB 3 VAL M 111  VAL M 114 -1  O  VAL M 113   N  ALA M  35           
SHEET    3  AB 3 LEU M  52  LEU M  55 -1  N  VAL M  54   O  VAL M 112           
SHEET    1  AC 4 PHE O  14  VAL O  16  0                                        
SHEET    2  AC 4 ALA O  78  ARG O  84  1  O  HIS O  80   N  GLY O  15           
SHEET    3  AC 4 ILE O  19  PHE O  20  1  N  ILE O  19   O  ARG O  84           
SHEET    4  AC 4 PHE O  27  VAL O  28 -1  O  PHE O  27   N  PHE O  20           
SHEET    1  AD 3 PHE O  14  VAL O  16  0                                        
SHEET    2  AD 3 ALA O  78  ARG O  84  1  O  HIS O  80   N  GLY O  15           
SHEET    3  AD 3 ARG O 111  ASP O 117  1  O  GLU O 116   N  ILE O  83           
SHEET    1  AE 3 VAL P  76  THR P  78  0                                        
SHEET    2  AE 3 VAL P  94  TYR P  97  1  O  TYR P  97   N  THR P  78           
SHEET    3  AE 3 PHE P 102  VAL P 105 -1  O  ASN P 103   N  VAL P  96           
SHEET    1  AF 4 SER Q   6  LYS Q  13  0                                        
SHEET    2  AF 4 ALA Q  16  LYS Q  23 -1  O  ALA Q  20   N  THR Q   9           
SHEET    3  AF 4 ASP Q  64  THR Q  70 -1  O  THR Q  70   N  THR Q  17           
SHEET    4  AF 4 ILE Q  29  VAL Q  31  1  N  LYS Q  30   O  VAL Q  67           
SHEET    1  AG 2 ASN R 101  VAL R 102  0                                        
SHEET    2  AG 2 SER R 120  VAL R 121  1  O  SER R 120   N  VAL R 102           
SHEET    1  AH 2 LEU S  15  ARG S  16  0                                        
SHEET    2  AH 2 ASN S  21  VAL S  22 -1  O  VAL S  22   N  LEU S  15           
SHEET    1  AI 2 GLY T  82  LYS T  84  0                                        
SHEET    2  AI 2 LYS T  92  VAL T  94 -1  O  VAL T  94   N  GLY T  82           
SHEET    1  AJ 2 VAL T 114  ILE T 116  0                                        
SHEET    2  AJ 2 ARG T 122  ILE T 124 -1  O  ARG T 123   N  GLU T 115           
SHEET    1  AK 4 VAL U  51  VAL U  56  0                                        
SHEET    2  AK 4 TYR U  90  GLU U  94 -1  O  GLU U  94   N  VAL U  51           
SHEET    3  AK 4 ILE U  22  THR U  27 -1  N  ILE U  24   O  ILE U  91           
SHEET    4  AK 4 ASP U 113  VAL U 116 -1  O  ASP U 113   N  THR U  27           
SHEET    1  AL 2 LYS U  61  VAL U  62  0                                        
SHEET    2  AL 2 ARG U  85  ILE U  86 -1  O  ILE U  86   N  LYS U  61           
SHEET    1  AM 3 ILE U  65  ARG U  68  0                                        
SHEET    2  AM 3 TRP U  79  GLU U  83 -1  O  ASP U  80   N  THR U  67           
SHEET    3  AM 3 TYR d  53  ARG d  56 -1  O  TYR d  53   N  GLU U  83           
SHEET    1  AN 2 ARG V  15  LYS V  16  0                                        
SHEET    2  AN 2 ILE V  23  ILE V  24 -1  O  ILE V  24   N  ARG V  15           
SHEET    1  AO 2 VAL V  32  GLN V  38  0                                        
SHEET    2  AO 2 ILE V  46  LEU V  55 -1  O  VAL V  51   N  ILE V  36           
SHEET    1  AP 3 ILE W 110  MET W 111  0                                        
SHEET    2  AP 3 TYR W 101  THR W 106 -1  N  LEU W 104   O  MET W 111           
SHEET    3  AP 3 GLY W 123  VAL W 129 -1  O  GLY W 127   N  ILE W 103           
SHEET    1  AQ 7 VAL X 130  SER X 131  0                                        
SHEET    2  AQ 7 LYS X 123  VAL X 127 -1  N  VAL X 127   O  VAL X 130           
SHEET    3  AQ 7 GLU X 101  ALA X 105 -1  N  ALA X 105   O  LYS X 123           
SHEET    4  AQ 7 HIS X  48  ILE X  57 -1  N  ALA X  49   O  LEU X 104           
SHEET    5  AQ 7 CYS X  71  LEU X  76 -1  O  GLN X  75   N  ILE X  52           
SHEET    6  AQ 7 LYS X  82  PHE X  86 -1  O  ALA X  85   N  VAL X  72           
SHEET    7  AQ 7 LYS X 123  VAL X 127  1  O  VAL X 124   N  PHE X  86           
SHEET    1  AR 4 ILE Y   7  ASN Y  15  0                                        
SHEET    2  AR 4 ARG Y  20  LEU Y  28 -1  O  ARG Y  20   N  ASN Y  15           
SHEET    3  AR 4 LYS Y  68  TYR Y  76 -1  O  GLY Y  71   N  VAL Y  25           
SHEET    4  AR 4 VAL Y  55  THR Y  62 -1  N  SER Y  56   O  LEU Y  74           
SHEET    1  AS 3 TYR Z  59  VAL Z  60  0                                        
SHEET    2  AS 3 TYR Z 101  ARG Z 103 -1  O  TYR Z 101   N  VAL Z  60           
SHEET    3  AS 3 ILE Z  89  PRO Z  91 -1  N  LYS Z  90   O  THR Z 102           
SHEET    1  AT 2 PRO a  20  ARG a  22  0                                        
SHEET    2  AT 2 SER a  29  PRO a  31 -1  O  VAL a  30   N  VAL a  21           
SHEET    1  AU 2 LYS a  37  ASN a  43  0                                        
SHEET    2  AU 2 LYS a  66  HIS a  72 -1  O  LEU a  71   N  ARG a  38           
SHEET    1  AV 2 PHE b  32  LYS b  36  0                                        
SHEET    2  AV 2 ILE b  43  PHE b  47 -1  O  THR b  44   N  VAL b  35           
SHEET    1  AW 2 CYS b  64  THR b  65  0                                        
SHEET    2  AW 2 LYS b  72  LEU b  73 -1  O  LYS b  72   N  THR b  65           
SHEET    1  AX 2 LEU d  30  ILE d  31  0                                        
SHEET    2  AX 2 ILE d  38  ASP d  39 -1  N  ILE d  38   O  ILE d  31           
SHEET    1  AY 3 LEU f 130  ASN f 132  0                                        
SHEET    2  AY 3 PHE f 137  CYS f 139 -1  O  TYR f 138   N  ALA f 131           
SHEET    3  AY 3 ALA f 147  THR f 148 -1  O  THR f 148   N  PHE f 137           
SHEET    1  AZ 4 ILE g   6  LEU g  14  0                                        
SHEET    2  AZ 4 ILE g 317  THR g 324 -1  O  MET g 323   N  MET g   7           
SHEET    3  AZ 4 THR g 307  TYR g 312 -1  N  LEU g 308   O  TRP g 320           
SHEET    4  AZ 4 ALA g 296  TRP g 301 -1  N  VAL g 297   O  GLY g 311           
SHEET    1  BA 4 SER g  23  LEU g  24  0                                        
SHEET    2  BA 4 LEU g  33  GLY g  37 -1  O  GLY g  37   N  SER g  23           
SHEET    3  BA 4 LEU g  43  LEU g  48 -1  O  ILE g  44   N  SER g  36           
SHEET    4  BA 4 GLY g  56  TYR g  62 -1  O  VAL g  57   N  ARG g  47           
SHEET    1  BB 4 VAL g  69  VAL g  74  0                                        
SHEET    2  BB 4 TYR g  80  SER g  85 -1  O  ALA g  84   N  ASP g  71           
SHEET    3  BB 4 LEU g  90  ASN g  94 -1  O  TRP g  93   N  ALA g  81           
SHEET    4  BB 4 ASN g  99  PHE g 104 -1  O  ALA g 102   N  LEU g  92           
SHEET    1  BC 4 VAL g 111  ILE g 116  0                                        
SHEET    2  BC 4 ILE g 123  SER g 127 -1  O  ALA g 126   N  LEU g 112           
SHEET    3  BC 4 ILE g 132  TRP g 135 -1  O  ARG g 133   N  SER g 125           
SHEET    4  BC 4 CYS g 141  LEU g 145 -1  O  ALA g 142   N  VAL g 134           
SHEET    1  BD 4 VAL g 152  ALA g 158  0                                        
SHEET    2  BD 4 ILE g 172  GLY g 178 -1  O  THR g 173   N  ALA g 158           
SHEET    3  BD 4 ILE g 182  LEU g 188 -1  O  ARG g 184   N  SER g 176           
SHEET    4  BD 4 ILE g 195  ILE g 200 -1  O  PHE g 199   N  VAL g 183           
SHEET    1  BE 4 ILE g 206  PRO g 211  0                                        
SHEET    2  BE 4 LEU g 217  GLY g 222 -1  O  ALA g 221   N  VAL g 208           
SHEET    3  BE 4 GLN g 226  ASN g 231 -1  O  TRP g 230   N  ALA g 218           
SHEET    4  BE 4 SER g 236  ALA g 237 -1  O  SER g 236   N  ASN g 231           
SHEET    1  BF 4 ILE g 206  PRO g 211  0                                        
SHEET    2  BF 4 LEU g 217  GLY g 222 -1  O  ALA g 221   N  VAL g 208           
SHEET    3  BF 4 GLN g 226  ASN g 231 -1  O  TRP g 230   N  ALA g 218           
SHEET    4  BF 4 PHE g 241  ASP g 242 -1  O  PHE g 241   N  ILE g 227           
SHEET    1  BG 4 VAL g 247  PHE g 252  0                                        
SHEET    2  BG 4 TRP g 258  THR g 263 -1  O  ALA g 262   N  ALA g 249           
SHEET    3  BG 4 ILE g 267  ASP g 271 -1  O  LYS g 268   N  ALA g 261           
SHEET    4  BG 4 LEU g 277  LEU g 281 -1  O  ASP g 279   N  ILE g 269           
SHEET    1  BH 6 GLN i  33  MET i  41  0                                        
SHEET    2  BH 6 ARG i  46  CYS i  51 -1  O  SER i  50   N  GLN i  37           
SHEET    3  BH 6 MET i  58  ILE i  61 -1  O  ALA i  59   N  VAL i  47           
SHEET    4  BH 6 GLN i  88  LYS i  94  1  O  VAL i  91   N  HIS i  60           
SHEET    5  BH 6 ILE i  76  LEU i  81 -1  N  SER i  80   O  ASP i  90           
SHEET    6  BH 6 GLN i  33  MET i  41 -1  N  ALA i  36   O  ILE i  77           
SHEET    1  BI 5 GLU j  43  GLY j  44  0                                        
SHEET    2  BI 5 VAL j  34  LEU j  36 -1  N  VAL j  34   O  GLY j  44           
SHEET    3  BI 5 ASP j  18  ASN j  23 -1  N  ASN j  23   O  LYS j  35           
SHEET    4  BI 5 ASN j  68  VAL j  76 -1  O  ALA j  71   N  VAL j  20           
SHEET    5  BI 5 ILE j  83  SER j  86 -1  O  ASP j  84   N  ARG j  75           
SHEET    1  BJ 4 LYS j 219  LEU j 222  0                                        
SHEET    2  BJ 4 LEU j 227  GLN j 233 -1  O  THR j 231   N  LYS j 219           
SHEET    3  BJ 4 LYS j 183  VAL j 190 -1  N  VAL j 188   O  TYR j 228           
SHEET    4  BJ 4 CYS j 262  ILE j 264 -1  O  ASN j 263   N  GLU j 189           
SHEET    1  BK 6 GLY k 141  LYS k 149  0                                        
SHEET    2  BK 6 LYS k 184  ASP k 193 -1  O  PHE k 191   N  ALA k 143           
SHEET    3  BK 6 ASN k 102  GLY k 107  1  N  ILE k 103   O  VAL k 192           
SHEET    4  BK 6 ALA k 213  ILE k 218  1  O  ALA k 213   N  GLY k 104           
SHEET    5  BK 6 HIS k 243  GLN k 248  1  O  LEU k 247   N  LEU k 216           
SHEET    6  BK 6 ILE k 280  PRO k 282  1  O  VAL k 281   N  GLN k 248           
SHEET    1  BL 7 ARG k 314  VAL k 317  0                                        
SHEET    2  BL 7 GLY k 336  ASN k 344 -1  O  SER k 341   N  ILE k 316           
SHEET    3  BL 7 LEU k 395  THR k 400 -1  O  ILE k 396   N  GLY k 340           
SHEET    4  BL 7 CYS k 370  PHE k 381 -1  N  VAL k 378   O  GLY k 399           
SHEET    5  BL 7 GLU k 352  VAL k 360 -1  N  ILE k 353   O  SER k 375           
SHEET    6  BL 7 GLN k 415  VAL k 417 -1  O  VAL k 416   N  ARG k 356           
SHEET    7  BL 7 ARG k 314  VAL k 317 -1  N  LEU k 315   O  VAL k 417           
SHEET    1  BM 2 PHE k 347  LYS k 348  0                                        
SHEET    2  BM 2 PHE k 389  ALA k 390 -1  O  ALA k 390   N  PHE k 347           
SHEET    1  BN 7 ASN k 425  LEU k 436  0                                        
SHEET    2  BN 7 MET k 482  THR k 493 -1  O  ALA k 483   N  ILE k 432           
SHEET    3  BN 7 THR k 471  VAL k 478 -1  N  ARG k 474   O  GLN k 486           
SHEET    4  BN 7 VAL k 461  ILE k 466 -1  N  LEU k 462   O  ALA k 473           
SHEET    5  BN 7 LYS k 498  ARG k 504 -1  O  SER k 502   N  MET k 463           
SHEET    6  BN 7 TRP k 509  ILE k 517 -1  O  GLY k 513   N  LEU k 501           
SHEET    7  BN 7 ASN k 425  LEU k 436 -1  N  PHE k 435   O  TRP k 514           
SHEET    1  BO 4 LEU l 166  ASP l 168  0                                        
SHEET    2  BO 4 LYS l 171  PHE l 174 -1  O  LYS l 171   N  ASP l 168           
SHEET    3  BO 4 ARG l 210  ILE l 213 -1  O  ILE l 213   N  THR l 172           
SHEET    4  BO 4 SER l 204  ASP l 206 -1  N  SER l 204   O  VAL l 212           
SHEET    1  BP 5 GLY m  66  LYS m  70  0                                        
SHEET    2  BP 5 GLU m  76  GLN m  81 -1  O  GLN m  79   N  ASN m  67           
SHEET    3  BP 5 THR m  38  GLN m  43 -1  N  THR m  40   O  LEU m  80           
SHEET    4  BP 5 ILE m  26  GLN m  32 -1  N  ARG m  29   O  THR m  41           
SHEET    5  BP 5 ILE m 103  ILE m 105  1  O  LYS m 104   N  ILE m  26           
SHEET    1  BQ 4 ALA q   3  LEU q   6  0                                        
SHEET    2  BQ 4 ILE q 317  HIS q 321 -1  O  LEU q 319   N  ILE q   4           
SHEET    3  BQ 4 SER q 307  GLY q 311 -1  N  SER q 310   O  ARG q 318           
SHEET    4  BQ 4 THR q 298  ILE q 301 -1  N  THR q 298   O  GLY q 311           
SHEET    1  BR 4 LEU q  13  TYR q  18  0                                        
SHEET    2  BR 4 LEU q  24  SER q  29 -1  O  PHE q  26   N  LYS q  17           
SHEET    3  BR 4 ALA q  34  TYR q  38 -1  O  SER q  35   N  SER q  27           
SHEET    4  BR 4 ARG q  44  LEU q  48 -1  O  GLY q  46   N  VAL q  36           
SHEET    1  BS 4 THR q  54  VAL q  60  0                                        
SHEET    2  BS 4 TYR q  66  ALA q  72 -1  O  VAL q  68   N  ASP q  59           
SHEET    3  BS 4 SER q  75  ASP q  80 -1  O  TRP q  79   N  CYS q  67           
SHEET    4  BS 4 CYS q  86  LYS q  91 -1  O  TRP q  90   N  ILE q  76           
SHEET    1  BT 4 VAL q  96  PHE q 101  0                                        
SHEET    2  BT 4 TYR q 107  LEU q 112 -1  O  ILE q 111   N  LYS q  97           
SHEET    3  BT 4 SER q 121  ARG q 129 -1  O  SER q 121   N  LEU q 112           
SHEET    4  BT 4 LEU q 136  VAL q 139 -1  O  LYS q 138   N  GLU q 128           
SHEET    1  BU 4 VAL q  96  PHE q 101  0                                        
SHEET    2  BU 4 TYR q 107  LEU q 112 -1  O  ILE q 111   N  LYS q  97           
SHEET    3  BU 4 SER q 121  ARG q 129 -1  O  SER q 121   N  LEU q 112           
SHEET    4  BU 4 HIS q 145  ILE q 148 -1  O  ILE q 147   N  ILE q 122           
SHEET    1  BV 4 ALA q 156  TRP q 161  0                                        
SHEET    2  BV 4 TYR q 167  HIS q 172 -1  O  GLY q 171   N  VAL q 158           
SHEET    3  BV 4 LYS q 176  ASP q 181 -1  O  SER q 178   N  ALA q 170           
SHEET    4  BV 4 GLU q 187  ASP q 193 -1  O  VAL q 189   N  LYS q 179           
SHEET    1  BW 4 ILE q 199  PHE q 204  0                                        
SHEET    2  BW 4 TYR q 210  SER q 215 -1  O  ILE q 212   N  GLN q 203           
SHEET    3  BW 4 ASN q 219  ASP q 224 -1  O  VAL q 223   N  PHE q 211           
SHEET    4  BW 4 GLN q 229  GLU q 235 -1  O  TYR q 234   N  SER q 220           
SHEET    1  BX 4 LEU q 240  ILE q 245  0                                        
SHEET    2  BX 4 PHE q 251  GLY q 256 -1  O  GLY q 255   N  ASN q 241           
SHEET    3  BX 4 ALA q 275  HIS q 279 -1  O  TYR q 278   N  ILE q 252           
SHEET    4  BX 4 GLU q 285  VAL q 289 -1  O  GLY q 287   N  PHE q 277           
LINK         O3'   U 1   8                 P   1MG 1   9     1555   1555  1.62  
LINK         O3' 1MG 1   9                 P   2MG 1  10     1555   1555  1.61  
LINK         O3' 2MG 1  10                 P     C 1  11     1555   1555  1.61  
LINK         O3'   G 1  15                 P   H2U 1  16     1555   1555  1.60  
LINK         O3' H2U 1  16                 P     G 1  18     1555   1555  1.60  
LINK         O3'   C 1  25                 P   M2G 1  26     1555   1555  1.61  
LINK         O3' M2G 1  26                 P     C 1  27     1555   1555  1.61  
LINK         O3'   U 1  36                 P   T6A 1  37     1555   1555  1.62  
LINK         O3' T6A 1  37                 P     A 1  38     1555   1555  1.62  
LINK         O3'   U 1  45                 P   7MG 1  46     1555   1555  1.61  
LINK         O3' 7MG 1  46                 P   H2U 1  47     1555   1555  1.61  
LINK         O3' H2U 1  47                 P   5MC 1  48     1555   1555  1.61  
LINK         O3' 5MC 1  48                 P   5MC 1  49     1555   1555  1.61  
LINK         O3' 5MC 1  49                 P     U 1  50     1555   1555  1.61  
LINK         O3'   G 1  57                 P   1MA 1  58     1555   1555  1.61  
LINK         O3' 1MA 1  58                 P     A 1  59     1555   1555  1.61  
LINK         O3'   G 1  63                 P   RIA 1  64     1555   1555  1.59  
LINK         O3A RIA 1  64                 P     G 1  65     1555   1555  1.59  
LINK         OP2   A 2 618                MG    MG 21824     1555   1555  1.71  
LINK         OP2   G 21427                MG    MG 21878     1555   1555  1.80  
LINK         OP2   A 2 459                MG    MG 21835     1555   1555  1.90  
LINK         OP2   A 2 377                MG    MG 21815     1555   1555  1.91  
LINK         OP1   G 2 573                MG    MG 21809     1555   1555  1.91  
LINK         OP1   C 21176                MG    MG 21871     1555   1555  1.93  
LINK         OP2   G 2 362                MG    MG 21801     1555   1555  1.96  
LINK         OP2   G 21791                MG    MG 21832     1555   1555  1.96  
LINK         OP2   G 2  95                MG    MG 21830     1555   1555  1.97  
LINK        MG    MG k 602                 O1G GCP k 603     1555   1555  1.98  
LINK         OP2   A 2 622                MG    MG 21837     1555   1555  1.98  
LINK         OP2   A 2 622                MG    MG 21825     1555   1555  1.98  
LINK         OP2   G 21537                MG    MG 21876     1555   1555  1.98  
LINK         OP1   A 21761                MG    MG 21811     1555   1555  1.98  
LINK         OP2   A 2 555                MG    MG 21803     1555   1555  1.98  
LINK         OP2   C 2  49                MG    MG 21807     1555   1555  1.98  
LINK         OP1   G 21791                MG    MG 21832     1555   1555  1.98  
LINK         OP1   U 2  94                MG    MG 21830     1555   1555  1.98  
LINK         OP1   U 2  44                MG    MG 21820     1555   1555  1.98  
LINK         OP2   U 21768                MG    MG 21829     1555   1555  1.98  
LINK         OP2   A 2 212                MG    MG 21854     1555   1555  1.98  
LINK         OP1   A 2 100                MG    MG 21804     1555   1555  1.98  
LINK         OP1   U 2 169                MG    MG 21833     1555   1555  1.99  
LINK         OP2   A 21760                MG    MG 21821     1555   1555  1.99  
LINK         OP2   A 2 760                MG    MG 21847     1555   1555  1.99  
LINK         OP1   U 2  64                MG    MG 21833     1555   1555  1.99  
LINK         OP1   C 21587                MG    MG 21869     1555   1555  1.99  
LINK         OP1   G 21766                MG    MG 21811     1555   1555  1.99  
LINK         OP2   U 2 101                MG    MG 21826     1555   1555  1.99  
LINK         OP2   G 21327                MG    MG 21864     1555   1555  1.99  
LINK         OP1   U 21769                MG    MG 21811     1555   1555  2.01  
LINK         OP2   C 21176                MG    MG 21871     1555   1555  2.10  
LINK         OP2   A 2 928                MG    MG 21810     1555   1555  2.10  
LINK         O6    G 21270                MG    MG 21873     1555   1555  2.14  
LINK         O3'   G 21106                MG    MG 21828     1555   1555  2.18  
LINK         O4    U 21116                MG    MG 21860     1555   1555  2.19  
LINK         OP2   U 2  94                MG    MG 21830     1555   1555  2.20  
LINK         SG  CYS a  74                ZN    ZN a 500     1555   1555  2.20  
LINK         OP1   G 21107                MG    MG 21828     1555   1555  2.23  
LINK         OP1   A 2 618                MG    MG 21824     1555   1555  2.23  
LINK         O2    C 21600                MG    MG 21872     1555   1555  2.24  
LINK         OP1   A 2 622                MG    MG 21825     1555   1555  2.24  
LINK         OP1   G 21046                MG    MG 21841     1555   1555  2.27  
LINK         O4    U 2 885                MG    MG 21862     1555   1555  2.27  
LINK         O6    G 21539                MG    MG 21876     1555   1555  2.28  
LINK         OP1   G 2 606                MG    MG 21817     1555   1555  2.29  
LINK         SG  CYS b  40                ZN    ZN b 101     1555   1555  2.31  
LINK         O5'   G 21537                MG    MG 21876     1555   1555  2.32  
LINK         OP2   A 2  47                MG    MG 21820     1555   1555  2.32  
LINK         O3'   G 21790                MG    MG 21832     1555   1555  2.34  
LINK         O6    G 2 924                MG    MG 21862     1555   1555  2.35  
LINK         O5'   A 2 555                MG    MG 21803     1555   1555  2.35  
LINK         O3'   C 2 572                MG    MG 21809     1555   1555  2.35  
LINK         O3'   G 2  63                MG    MG 21833     1555   1555  2.36  
LINK         O5'   G 21427                MG    MG 21878     1555   1555  2.37  
LINK         SG  CYS f 139                ZN    ZN f 501     1555   1555  2.38  
LINK         OP2   C 2 353                MG    MG 21840     1555   1555  2.38  
LINK         O2    C 2 401                MG    MG 21813     1555   1555  2.39  
LINK         OP2   A 2 549                MG    MG 21839     1555   1555  2.39  
LINK         SG  CYS b  37                ZN    ZN b 101     1555   1555  2.41  
LINK         O3'   A 2 621                MG    MG 21837     1555   1555  2.41  
LINK         OP2   G 2 606                MG    MG 21817     1555   1555  2.42  
LINK         OP2   A 21646                MG    MG 21834     1555   1555  2.42  
LINK         O6    G 2 383                MG    MG 21858     1555   1555  2.42  
LINK         O5'   C 2 353                MG    MG 21840     1555   1555  2.43  
LINK         OP2   U 2 607                MG    MG 21814     1555   1555  2.43  
LINK         OP2   A 2 400                MG    MG 21813     1555   1555  2.43  
LINK         OP2   A 21328                MG    MG 21864     1555   1555  2.43  
LINK         OG1 THR k 137                MG    MG k 602     1555   1555  2.45  
LINK         OP2   C 21273                MG    MG 21875     1555   1555  2.45  
LINK         O5'   G 21327                MG    MG 21864     1555   1555  2.46  
LINK         O2'   U 2 872                MG    MG 21841     1555   1555  2.48  
LINK         OP1   A 2  28                MG    MG 21816     1555   1555  2.49  
LINK         O3'   G 2 458                MG    MG 21835     1555   1555  2.49  
LINK         OP1   G 21013                MG    MG 21838     1555   1555  2.49  
LINK         O3'   G 21765                MG    MG 21811     1555   1555  2.50  
LINK         O6    G 21636                MG    MG 21856     1555   1555  2.50  
LINK         O4    U 2  98                MG    MG 21858     1555   1555  2.51  
LINK         OP2   A 2  93                MG    MG 21802     1555   1555  2.51  
LINK         O4    U 21271                MG    MG 21873     1555   1555  2.52  
LINK         OP1   G 21427                MG    MG 21878     1555   1555  2.52  
LINK         O5'   U 2 759                MG    MG 21847     1555   1555  2.53  
LINK         OP1   C 2 989                MG    MG 21859     1555   1555  2.53  
LINK         OP1   A 2 619                MG    MG 21824     1555   1555  2.53  
LINK         OP2   A 2 100                MG    MG 21826     1555   1555  2.53  
LINK         OP2   U 2 759                MG    MG 21847     1555   1555  2.57  
LINK         O2'   U 2 934                MG    MG 21857     1555   1555  2.59  
LINK         OP2   A 21004                MG    MG 21808     1555   1555  2.61  
LINK         SG  CYS a  23                ZN    ZN a 500     1555   1555  2.61  
LINK         SG  CYS f 124                ZN    ZN f 501     1555   1555  2.62  
LINK         O4    U 2 312                MG    MG 21860     1555   1555  2.62  
LINK         OP2   G 21140                MG    MG 21848     1555   1555  2.64  
LINK         O4    U 2 998                MG    MG 21818     1555   1555  2.64  
LINK         N   CYS f 142                ZN    ZN f 501     1555   1555  2.65  
LINK         OP2   G 2 460                MG    MG 21835     1555   1555  2.66  
LINK         O6    G 2  89                MG    MG 21846     1555   1555  2.66  
LINK         OP2   G 21766                MG    MG 21821     1555   1555  2.68  
LINK         O2'   U 2 927                MG    MG 21810     1555   1555  2.69  
LINK         O4    U 2 842                MG    MG 21849     1555   1555  2.69  
LINK         OP2   C 2 404                MG    MG 21843     1555   1555  2.70  
LINK         O4    U 21394                MG    MG 21867     1555   1555  2.72  
LINK         OP2   A 2 100                MG    MG 21804     1555   1555  2.74  
LINK         O4    U 2 102                MG    MG 21826     1555   1555  2.74  
LINK         OP2   G 21426                MG    MG 21875     1555   1555  2.74  
LINK         O3'   U 2 581                MG    MG 21839     1555   1555  2.76  
LINK         OP2   U 2 378                MG    MG 21815     1555   1555  2.78  
LINK         OP1   G 21327                MG    MG 21864     1555   1555  2.80  
LINK         OP1   C 21273                MG    MG 21875     1555   1555  2.81  
LINK         OP2   A 2 514                MG    MG 21850     1555   1555  2.83  
LINK         OP1   G 21433                MG    MG 21874     1555   1555  2.84  
LINK         O6    G 2 547                MG    MG 21812     1555   1555  2.85  
LINK         O4'   U 2 607                MG    MG 21814     1555   1555  2.85  
LINK         OP1   U 21628                MG    MG 21832     1555   1555  2.86  
LINK         OP1   G 21426                MG    MG 21875     1555   1555  2.86  
LINK         OP2   A 2 620                MG    MG 21822     1555   1555  2.88  
LINK         O5'   G 21539                MG    MG 21866     1555   1555  2.91  
LINK         O3'   U 21759                MG    MG 21821     1555   1555  2.91  
LINK         O5'   U 2  94                MG    MG 21830     1555   1555  2.93  
LINK         OP2   A 2 992                MG    MG 21842     1555   1555  2.94  
LINK         O6    G 2 561                MG    MG 21823     1555   1555  2.95  
LINK         OP1   G 21010                MG    MG 21853     1555   1555  2.96  
LINK         O3'   G 2 403                MG    MG 21843     1555   1555  2.96  
LINK         OP2   G 21291                MG    MG 21851     1555   1555  2.96  
LINK         OD2 ASP k 193                MG    MG k 602     1555   1555  2.97  
LINK         OP2   A 2 619                MG    MG 21824     1555   1555  2.99  
LINK         O5'   C 2 267                MG    MG 21833     1555   1555  2.99  
LINK         O5'   C 2  49                MG    MG 21807     1555   1555  3.00  
SITE     1 AC1  2   G 2 362    G 2 376                                          
SITE     1 AC2  2   A 2  93    G 2 402                                          
SITE     1 AC3  3   G 2 551    A 2 555    G 2 556                               
SITE     1 AC4  2   A 2 100    C 2 360                                          
SITE     1 AC5  1   G 2 623                                                     
SITE     1 AC6  2   C 2 583    A 2 584                                          
SITE     1 AC7  1   C 2  49                                                     
SITE     1 AC8  3   U 21003    A 21004    C 21005                               
SITE     1 AC9  4   G 2   7    U 2   8    C 2 572    G 2 573                    
SITE     1 BC1  2   U 2 927    A 2 928                                          
SITE     1 BC2  4   A 21761    G 21765    G 21766    U 21769                    
SITE     1 BC3  3   U 2 546    G 2 547    G 2 548                               
SITE     1 BC4  2   A 2 400    C 2 401                                          
SITE     1 BC5  3   G 2  16    C 2  17    U 2 607                               
SITE     1 BC6  4   G 2 362    G 2 376    A 2 377    U 2 378                    
SITE     1 BC7  1   A 2  28                                                     
SITE     1 BC8  2   G 2 606    G 2 612                                          
SITE     1 BC9  4   A 2 997    U 2 998    A 21002    U 21003                    
SITE     1 CC1  2   A 2 427    G 2 428                                          
SITE     1 CC2  3   A 2  43    U 2  44    A 2  47                               
SITE     1 CC3  4   U 21759    A 21760    A 21761    G 21766                    
SITE     1 CC4  5   A 2 618    A 2 619    A 2 620    A 21029                    
SITE     2 CC4  5  MG 21824                                                     
SITE     1 CC5  3   G 2 561    U 2 562    A 2 579                               
SITE     1 CC6  5   U 2 617    A 2 618    A 2 619    A 21029                    
SITE     2 CC6  5  MG 21822                                                     
SITE     1 CC7  3   A 2 621    A 2 622    U 21030                               
SITE     1 CC8  4   A 2 100    U 2 101    U 2 102    C 2 360                    
SITE     1 CC9  2   A 2 604    A 2 605                                          
SITE     1 DC1  2   G 21106    G 21107                                          
SITE     1 DC2  2   U 21768  LEU O 137                                          
SITE     1 DC3  2   U 2  94    G 2  95                                          
SITE     1 DC4  3   G 21670    G 21671    C 21672                               
SITE     1 DC5  3   U 21628    G 21790    G 21791                               
SITE     1 DC6  5   G 2  63    U 2  64    U 2 169    U 2 266                    
SITE     2 DC6  5   C 2 267                                                     
SITE     1 DC7  1   A 21646                                                     
SITE     1 DC8  3   G 2 458    A 2 459    G 2 460                               
SITE     1 DC9  1   G 2 466                                                     
SITE     1 EC1  4   A 2 621    A 2 622    C 2 624    U 21030                    
SITE     1 EC2  2   G 2 983    G 21013                                          
SITE     1 EC3  3   A 2 549    U 2 581    C 2 582                               
SITE     1 EC4  2   C 2 353    G 2 354                                          
SITE     1 EC5  2   U 2 872    G 21046                                          
SITE     1 EC6  2   A 2 991    A 2 992                                          
SITE     1 EC7  2   G 2 403    C 2 404                                          
SITE     1 EC8  1   U 21301                                                     
SITE     1 EC9  3   G 2 979    U 2 980    U 21014                               
SITE     1 FC1  3   U 2  88    G 2  89    C 2  90                               
SITE     1 FC2  2   U 2 759    A 2 760                                          
SITE     1 FC3  2   G 21139    G 21140                                          
SITE     1 FC4  1   U 2 842                                                     
SITE     1 FC5  3   A 2 514    G 2 515    G 2 536                               
SITE     1 FC6  2   G 21290    G 21291                                          
SITE     1 FC7  2   C 21009    G 21010                                          
SITE     1 FC8  2   U 2 211    A 2 212                                          
SITE     1 FC9  3   G 2 329    G 2 335    G 2 336                               
SITE     1 GC1  2   G 21636    C 21637                                          
SITE     1 GC2  2   U 2 934  TYR B 155                                          
SITE     1 GC3  4   U 2  98    C 2  99    G 2 383    A 2 384                    
SITE     1 GC4  2   C 2 989  LYS O 129                                          
SITE     1 GC5  5   U 2 312    U 21116    G 21117    U 21128                    
SITE     2 GC5  5   G 21129                                                     
SITE     1 GC6  1   U 21054                                                     
SITE     1 GC7  5   G 2 884    U 2 885    A 2 886    G 2 924                    
SITE     2 GC7  5   A 2 925                                                     
SITE     1 GC8  3   A 21330    C 21331    C 21418                               
SITE     1 GC9  4   G 21327    A 21328    G 21329  SER D 160                    
SITE     1 HC1  2   A 21415    G 21416                                          
SITE     1 HC2  3   C 21474    G 21539    G 21540                               
SITE     1 HC3  2   G 21393    U 21394                                          
SITE     1 HC4  3   C 21191    A 21192    U 21282                               
SITE     1 HC5  3   A 21467    G 21586    C 21587                               
SITE     1 HC6  1   G 21443                                                     
SITE     1 HC7  3   G 21175    C 21176    U 21186                               
SITE     1 HC8  3   G 21200    G 21592    C 21600                               
SITE     1 HC9  3   G 21270    U 21271    C 21437                               
SITE     1 IC1  3   U 21432    G 21433  SER d  24                               
SITE     1 IC2  5   G 21272    C 21273    G 21426    G 21427                    
SITE     2 IC2  5  MG 21878                                                     
SITE     1 IC3  3   G 21537    G 21539  ARG S  40                               
SITE     1 IC4  5   G 21272    G 21426    G 21427    U 21428                    
SITE     2 IC4  5  MG 21875                                                     
SITE     1 IC5  4   A 21202    C 21455    A 21554    U 21558                    
SITE     1 IC6  1 LYS C 121                                                     
SITE     1 IC7  2 PHE Q 138  LYS U  77                                          
SITE     1 IC8  4 CYS a  23  CYS a  26  CYS a  74  CYS a  77                    
SITE     1 IC9  5 CYS b  37  CYS b  40  CYS b  56  SER b  58                    
SITE     2 IC9  5 CYS b  59                                                     
SITE     1 JC1  4 CYS f 124  CYS f 139  LYS f 141  CYS f 142                    
SITE     1 JC2  3   A 1  76  GLU k 383  LEU k 395                               
SITE     1 JC3  4 THR k 137  ASP k 193  PRO k 195  GCP k 603                    
SITE     1 JC4 19 HIS k 108  ALA k 110  HIS k 111  GLY k 112                    
SITE     2 JC4 19 LYS k 113  SER k 114  THR k 115  ILE k 136                    
SITE     3 JC4 19 THR k 137  PRO k 195  GLY k 196  ASN k 249                    
SITE     4 JC4 19 LEU k 253  ALA k 285  GLN k 286   MG k 602                    
SITE     5 JC4 19 THR l 238  SER l 264  ARG l 266                               
SITE     1 JC5  5 CYS l 236  CYS l 239  SER l 241  CYS l 259                    
SITE     2 JC5  5 SER l 261                                                     
CRYST1    1.000    1.000    1.000  90.00  90.00  90.00 P 1           1          
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      1.000000  0.000000  0.000000        0.00000                         
SCALE2      0.000000  1.000000  0.000000        0.00000                         
SCALE3      0.000000  0.000000  1.000000        0.00000                         
(ATOM LINES ARE NOT SHOWN.)
END                                                                             
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