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Database: PDB
Entry: 3QNF
LinkDB: 3QNF
Original site: 3QNF 
HEADER    HYDROLASE                               08-FEB-11   3QNF              
TITLE     CRYSTAL STRUCTURE OF THE OPEN STATE OF HUMAN ENDOPLASMIC RETICULUM    
TITLE    2 AMINOPEPTIDASE 1 ERAP1                                               
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: ENDOPLASMIC RETICULUM AMINOPEPTIDASE 1;                    
COMPND   3 CHAIN: A, B, C;                                                      
COMPND   4 SYNONYM: ARTS-1, ADIPOCYTE-DERIVED LEUCINE AMINOPEPTIDASE, A-LAP,    
COMPND   5 AMINOPEPTIDASE PILS, PUROMYCIN-INSENSITIVE LEUCYL-SPECIFIC           
COMPND   6 AMINOPEPTIDASE, PILS-AP, TYPE 1 TUMOR NECROSIS FACTOR RECEPTOR       
COMPND   7 SHEDDING AMINOPEPTIDASE REGULATOR;                                   
COMPND   8 EC: 3.4.11.-;                                                        
COMPND   9 ENGINEERED: YES                                                      
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE   3 ORGANISM_COMMON: HUMAN;                                              
SOURCE   4 ORGANISM_TAXID: 9606;                                                
SOURCE   5 GENE: ERAP1, APPILS, ARTS1, KIAA0525, UNQ584/PRO1154;                
SOURCE   6 EXPRESSION_SYSTEM: TRICHOPLUSIA NI;                                  
SOURCE   7 EXPRESSION_SYSTEM_COMMON: CABBAGE LOOPER;                            
SOURCE   8 EXPRESSION_SYSTEM_TAXID: 7111                                        
KEYWDS    STRUCTURAL GENOMICS CONSORTIUM, SGC, GLYCOPROTEIN, METAL-BINDING,     
KEYWDS   2 METALLOPROTEASE, PROTEASE, ADAPTIVE IMMUNITY, HYDROLASE              
EXPDTA    X-RAY DIFFRACTION                                                     
AUTHOR    M.VOLLMAR,G.KOCHAN,T.KROJER,D.HARVEY,A.CHAIKUAD,C.ALLERSTON,          
AUTHOR   2 J.R.C.MUNIZ,J.RAYNOR,E.UGOCHUKWU,G.BERRIDGE,B.P.WORDSWORTH,F.VON     
AUTHOR   3 DELFT,C.BOUNTRA,C.H.ARROWSMITH,A.EDWARDS,K.KAVANAGH,U.OPPERMANN,     
AUTHOR   4 STRUCTURAL GENOMICS CONSORTIUM (SGC)                                 
REVDAT   4   31-JAN-18 3QNF    1       AUTHOR                                   
REVDAT   3   25-MAY-11 3QNF    1       JRNL                                     
REVDAT   2   27-APR-11 3QNF    1       JRNL                                     
REVDAT   1   23-FEB-11 3QNF    0                                                
JRNL        AUTH   G.KOCHAN,T.KROJER,D.HARVEY,R.FISCHER,L.CHEN,M.VOLLMAR,       
JRNL        AUTH 2 F.VON DELFT,K.L.KAVANAGH,M.A.BROWN,P.BOWNESS,P.WORDSWORTH,   
JRNL        AUTH 3 B.M.KESSLER,U.OPPERMANN                                      
JRNL        TITL   CRYSTAL STRUCTURES OF THE ENDOPLASMIC RETICULUM              
JRNL        TITL 2 AMINOPEPTIDASE-1 (ERAP1) REVEAL THE MOLECULAR BASIS FOR      
JRNL        TITL 3 N-TERMINAL PEPTIDE TRIMMING.                                 
JRNL        REF    PROC.NATL.ACAD.SCI.USA        V. 108  7745 2011              
JRNL        REFN                   ISSN 0027-8424                               
JRNL        PMID   21508329                                                     
JRNL        DOI    10.1073/PNAS.1101262108                                      
REMARK   2                                                                      
REMARK   2 RESOLUTION.    3.00 ANGSTROMS.                                       
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   PROGRAM     : REFMAC 5.5.0110                                      
REMARK   3   AUTHORS     : MURSHUDOV,VAGIN,DODSON                               
REMARK   3                                                                      
REMARK   3    REFINEMENT TARGET : MAXIMUM LIKELIHOOD                            
REMARK   3                                                                      
REMARK   3  DATA USED IN REFINEMENT.                                            
REMARK   3   RESOLUTION RANGE HIGH (ANGSTROMS) : 3.00                           
REMARK   3   RESOLUTION RANGE LOW  (ANGSTROMS) : 19.99                          
REMARK   3   DATA CUTOFF            (SIGMA(F)) : NULL                           
REMARK   3   COMPLETENESS FOR RANGE        (%) : 97.6                           
REMARK   3   NUMBER OF REFLECTIONS             : 56650                          
REMARK   3                                                                      
REMARK   3  FIT TO DATA USED IN REFINEMENT.                                     
REMARK   3   CROSS-VALIDATION METHOD          : THROUGHOUT                      
REMARK   3   FREE R VALUE TEST SET SELECTION  : RANDOM                          
REMARK   3   R VALUE     (WORKING + TEST SET) : 0.231                           
REMARK   3   R VALUE            (WORKING SET) : 0.229                           
REMARK   3   FREE R VALUE                     : 0.283                           
REMARK   3   FREE R VALUE TEST SET SIZE   (%) : 5.100                           
REMARK   3   FREE R VALUE TEST SET COUNT      : 3019                            
REMARK   3                                                                      
REMARK   3  FIT IN THE HIGHEST RESOLUTION BIN.                                  
REMARK   3   TOTAL NUMBER OF BINS USED           : 20                           
REMARK   3   BIN RESOLUTION RANGE HIGH       (A) : 3.00                         
REMARK   3   BIN RESOLUTION RANGE LOW        (A) : 3.08                         
REMARK   3   REFLECTION IN BIN     (WORKING SET) : 4094                         
REMARK   3   BIN COMPLETENESS (WORKING+TEST) (%) : 98.59                        
REMARK   3   BIN R VALUE           (WORKING SET) : 0.3200                       
REMARK   3   BIN FREE R VALUE SET COUNT          : 234                          
REMARK   3   BIN FREE R VALUE                    : 0.3870                       
REMARK   3                                                                      
REMARK   3  NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT.                    
REMARK   3   PROTEIN ATOMS            : 17494                                   
REMARK   3   NUCLEIC ACID ATOMS       : 0                                       
REMARK   3   HETEROGEN ATOMS          : 109                                     
REMARK   3   SOLVENT ATOMS            : 39                                      
REMARK   3                                                                      
REMARK   3  B VALUES.                                                           
REMARK   3   FROM WILSON PLOT           (A**2) : NULL                           
REMARK   3   MEAN B VALUE      (OVERALL, A**2) : 34.25                          
REMARK   3   OVERALL ANISOTROPIC B VALUE.                                       
REMARK   3    B11 (A**2) : 3.32000                                              
REMARK   3    B22 (A**2) : -1.74000                                             
REMARK   3    B33 (A**2) : -1.58000                                             
REMARK   3    B12 (A**2) : 0.00000                                              
REMARK   3    B13 (A**2) : 0.00000                                              
REMARK   3    B23 (A**2) : 0.00000                                              
REMARK   3                                                                      
REMARK   3  ESTIMATED OVERALL COORDINATE ERROR.                                 
REMARK   3   ESU BASED ON R VALUE                            (A): NULL          
REMARK   3   ESU BASED ON FREE R VALUE                       (A): 0.486         
REMARK   3   ESU BASED ON MAXIMUM LIKELIHOOD                 (A): 0.388         
REMARK   3   ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2): 20.826        
REMARK   3                                                                      
REMARK   3 CORRELATION COEFFICIENTS.                                            
REMARK   3   CORRELATION COEFFICIENT FO-FC      : 0.899                         
REMARK   3   CORRELATION COEFFICIENT FO-FC FREE : 0.846                         
REMARK   3                                                                      
REMARK   3  RMS DEVIATIONS FROM IDEAL VALUES        COUNT    RMS    WEIGHT      
REMARK   3   BOND LENGTHS REFINED ATOMS        (A): 18108 ; 0.008 ; 0.022       
REMARK   3   BOND LENGTHS OTHERS               (A): 11482 ; 0.002 ; 0.020       
REMARK   3   BOND ANGLES REFINED ATOMS   (DEGREES): 24725 ; 1.087 ; 1.949       
REMARK   3   BOND ANGLES OTHERS          (DEGREES): 28019 ; 0.834 ; 3.000       
REMARK   3   TORSION ANGLES, PERIOD 1    (DEGREES):  2285 ; 5.941 ; 5.000       
REMARK   3   TORSION ANGLES, PERIOD 2    (DEGREES):   724 ;37.351 ;23.881       
REMARK   3   TORSION ANGLES, PERIOD 3    (DEGREES):  2669 ;15.324 ;15.000       
REMARK   3   TORSION ANGLES, PERIOD 4    (DEGREES):    62 ;17.299 ;15.000       
REMARK   3   CHIRAL-CENTER RESTRAINTS       (A**3):  2876 ; 0.073 ; 0.200       
REMARK   3   GENERAL PLANES REFINED ATOMS      (A): 20193 ; 0.004 ; 0.021       
REMARK   3   GENERAL PLANES OTHERS             (A):  3749 ; 0.001 ; 0.020       
REMARK   3   NON-BONDED CONTACTS REFINED ATOMS (A):  NULL ;  NULL ;  NULL       
REMARK   3   NON-BONDED CONTACTS OTHERS        (A):  NULL ;  NULL ;  NULL       
REMARK   3   NON-BONDED TORSION REFINED ATOMS  (A):  NULL ;  NULL ;  NULL       
REMARK   3   NON-BONDED TORSION OTHERS         (A):  NULL ;  NULL ;  NULL       
REMARK   3   H-BOND (X...Y) REFINED ATOMS      (A):  NULL ;  NULL ;  NULL       
REMARK   3   H-BOND (X...Y) OTHERS             (A):  NULL ;  NULL ;  NULL       
REMARK   3   POTENTIAL METAL-ION REFINED ATOMS (A):  NULL ;  NULL ;  NULL       
REMARK   3   POTENTIAL METAL-ION OTHERS        (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY VDW REFINED ATOMS        (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY VDW OTHERS               (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY H-BOND REFINED ATOMS     (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY H-BOND OTHERS            (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY METAL-ION REFINED ATOMS  (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY METAL-ION OTHERS         (A):  NULL ;  NULL ;  NULL       
REMARK   3                                                                      
REMARK   3  ISOTROPIC THERMAL FACTOR RESTRAINTS.     COUNT   RMS    WEIGHT      
REMARK   3   MAIN-CHAIN BOND REFINED ATOMS  (A**2): 11475 ; 2.109 ; 3.000       
REMARK   3   MAIN-CHAIN BOND OTHER ATOMS    (A**2):  4611 ; 0.314 ; 3.000       
REMARK   3   MAIN-CHAIN ANGLE REFINED ATOMS (A**2): 18305 ; 3.888 ; 5.000       
REMARK   3   MAIN-CHAIN ANGLE OTHER ATOMS   (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SIDE-CHAIN BOND REFINED ATOMS  (A**2):  6633 ; 5.549 ; 7.000       
REMARK   3   SIDE-CHAIN BOND OTHER ATOMS    (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SIDE-CHAIN ANGLE REFINED ATOMS (A**2):  6415 ; 7.851 ; 9.000       
REMARK   3   SIDE-CHAIN ANGLE OTHER ATOMS   (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   LONG RANGE B REFINED ATOMS     (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   LONG RANGE B OTHER ATOMS       (A**2):  NULL ;  NULL ;  NULL       
REMARK   3                                                                      
REMARK   3 ANISOTROPIC THERMAL FACTOR RESTRAINTS.    COUNT   RMS   WEIGHT       
REMARK   3   RIGID-BOND RESTRAINTS          (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SPHERICITY; FREE ATOMS         (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SPHERICITY; BONDED ATOMS       (A**2):  NULL ;  NULL ;  NULL       
REMARK   3                                                                      
REMARK   3  NCS RESTRAINTS STATISTICS                                           
REMARK   3   NUMBER OF DIFFERENT NCS GROUPS : 51                                
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 1                                  
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B     46       B      70      1                      
REMARK   3           1     A     46       A      70      1                      
REMARK   3           1     C     46       C      70      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL   1    B    (A):    335 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL   1    A    (A):    335 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL   1    C    (A):    335 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL      1    B (A**2):    335 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL      1    A (A**2):    335 ; 0.060 ; 0.500           
REMARK   3   TIGHT THERMAL      1    C (A**2):    335 ; 0.060 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 2                                  
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B     71       B      75      1                      
REMARK   3           1     A     71       A      75      1                      
REMARK   3           1     C     71       C      75      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL   2    B    (A):     50 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL   2    A    (A):     50 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL   2    C    (A):     50 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL      2    B (A**2):     50 ; 0.030 ; 0.500           
REMARK   3   TIGHT THERMAL      2    A (A**2):     50 ; 0.040 ; 0.500           
REMARK   3   TIGHT THERMAL      2    C (A**2):     50 ; 0.050 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 3                                  
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B     76       B      87      1                      
REMARK   3           1     A     76       A      87      1                      
REMARK   3           1     C     76       C      87      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL   3    B    (A):    132 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL   3    A    (A):    132 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL   3    C    (A):    132 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL      3    B (A**2):    132 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL      3    A (A**2):    132 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL      3    C (A**2):    132 ; 0.070 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 4                                  
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B     88       B      92      1                      
REMARK   3           1     A     88       A      92      1                      
REMARK   3           1     C     88       C      92      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL   4    B    (A):     59 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL   4    A    (A):     59 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL   4    C    (A):     59 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL      4    B (A**2):     59 ; 0.040 ; 0.500           
REMARK   3   TIGHT THERMAL      4    A (A**2):     59 ; 0.040 ; 0.500           
REMARK   3   TIGHT THERMAL      4    C (A**2):     59 ; 0.050 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 5                                  
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B     93       B      98      1                      
REMARK   3           1     A     93       A      98      1                      
REMARK   3           1     C     93       C      98      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL   5    B    (A):     81 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL   5    A    (A):     81 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL   5    C    (A):     81 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL      5    B (A**2):     81 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL      5    A (A**2):     81 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL      5    C (A**2):     81 ; 0.060 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 6                                  
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B     99       B     104      1                      
REMARK   3           1     A     99       A     104      1                      
REMARK   3           1     C     99       C     104      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL   6    B    (A):     60 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL   6    A    (A):     60 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL   6    C    (A):     60 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL      6    B (A**2):     60 ; 0.030 ; 0.500           
REMARK   3   TIGHT THERMAL      6    A (A**2):     60 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL      6    C (A**2):     60 ; 0.050 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 7                                  
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    105       B     108      1                      
REMARK   3           1     A    105       A     108      1                      
REMARK   3           1     C    105       C     108      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL   7    B    (A):     54 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL   7    A    (A):     54 ; 0.010 ; 0.050           
REMARK   3   TIGHT POSITIONAL   7    C    (A):     54 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL      7    B (A**2):     54 ; 0.040 ; 0.500           
REMARK   3   TIGHT THERMAL      7    A (A**2):     54 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL      7    C (A**2):     54 ; 0.050 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 8                                  
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    116       B     125      1                      
REMARK   3           1     A    116       A     125      1                      
REMARK   3           1     C    116       C     125      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL   8    B    (A):    106 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL   8    A    (A):    106 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL   8    C    (A):    106 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL      8    B (A**2):    106 ; 0.040 ; 0.500           
REMARK   3   TIGHT THERMAL      8    A (A**2):    106 ; 0.060 ; 0.500           
REMARK   3   TIGHT THERMAL      8    C (A**2):    106 ; 0.050 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 9                                  
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    126       B     129      1                      
REMARK   3           1     A    126       A     129      1                      
REMARK   3           1     C    126       C     129      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL   9    B    (A):     51 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL   9    A    (A):     51 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL   9    C    (A):     51 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL      9    B (A**2):     51 ; 0.040 ; 0.500           
REMARK   3   TIGHT THERMAL      9    A (A**2):     51 ; 0.040 ; 0.500           
REMARK   3   TIGHT THERMAL      9    C (A**2):     51 ; 0.050 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 10                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    130       B     134      1                      
REMARK   3           1     A    130       A     134      1                      
REMARK   3           1     C    130       C     134      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  10    B    (A):     61 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  10    A    (A):     61 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  10    C    (A):     61 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     10    B (A**2):     61 ; 0.040 ; 0.500           
REMARK   3   TIGHT THERMAL     10    A (A**2):     61 ; 0.060 ; 0.500           
REMARK   3   TIGHT THERMAL     10    C (A**2):     61 ; 0.050 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 11                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    135       B     137      1                      
REMARK   3           1     A    135       A     137      1                      
REMARK   3           1     C    135       C     137      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  11    B    (A):     28 ; 0.010 ; 0.050           
REMARK   3   TIGHT POSITIONAL  11    A    (A):     28 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  11    C    (A):     28 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     11    B (A**2):     28 ; 0.030 ; 0.500           
REMARK   3   TIGHT THERMAL     11    A (A**2):     28 ; 0.040 ; 0.500           
REMARK   3   TIGHT THERMAL     11    C (A**2):     28 ; 0.050 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 12                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    138       B     142      1                      
REMARK   3           1     A    138       A     142      1                      
REMARK   3           1     C    138       C     142      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  12    B    (A):     57 ; 0.010 ; 0.050           
REMARK   3   TIGHT POSITIONAL  12    A    (A):     57 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  12    C    (A):     57 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     12    B (A**2):     57 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     12    A (A**2):     57 ; 0.040 ; 0.500           
REMARK   3   TIGHT THERMAL     12    C (A**2):     57 ; 0.050 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 13                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    143       B     156      1                      
REMARK   3           1     A    143       A     156      1                      
REMARK   3           1     C    143       C     156      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  13    B    (A):    166 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  13    A    (A):    166 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  13    C    (A):    166 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     13    B (A**2):    166 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     13    A (A**2):    166 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     13    C (A**2):    166 ; 0.060 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 14                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    157       B     163      1                      
REMARK   3           1     A    157       A     163      1                      
REMARK   3           1     C    157       C     163      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  14    B    (A):    100 ; 0.010 ; 0.050           
REMARK   3   TIGHT POSITIONAL  14    A    (A):    100 ; 0.010 ; 0.050           
REMARK   3   TIGHT POSITIONAL  14    C    (A):    100 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     14    B (A**2):    100 ; 0.040 ; 0.500           
REMARK   3   TIGHT THERMAL     14    A (A**2):    100 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     14    C (A**2):    100 ; 0.040 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 15                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    164       B     167      1                      
REMARK   3           1     A    164       A     167      1                      
REMARK   3           1     C    164       C     167      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  15    B    (A):     44 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  15    A    (A):     44 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  15    C    (A):     44 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     15    B (A**2):     44 ; 0.030 ; 0.500           
REMARK   3   TIGHT THERMAL     15    A (A**2):     44 ; 0.040 ; 0.500           
REMARK   3   TIGHT THERMAL     15    C (A**2):     44 ; 0.030 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 16                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    168       B     173      1                      
REMARK   3           1     A    168       A     173      1                      
REMARK   3           1     C    168       C     173      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  16    B    (A):     45 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  16    A    (A):     45 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  16    C    (A):     45 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     16    B (A**2):     45 ; 0.030 ; 0.500           
REMARK   3   TIGHT THERMAL     16    A (A**2):     45 ; 0.030 ; 0.500           
REMARK   3   TIGHT THERMAL     16    C (A**2):     45 ; 0.030 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 17                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    174       B     180      1                      
REMARK   3           1     A    174       A     180      1                      
REMARK   3           1     C    174       C     180      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  17    B    (A):     84 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  17    A    (A):     84 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  17    C    (A):     84 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     17    B (A**2):     84 ; 0.040 ; 0.500           
REMARK   3   TIGHT THERMAL     17    A (A**2):     84 ; 0.040 ; 0.500           
REMARK   3   TIGHT THERMAL     17    C (A**2):     84 ; 0.040 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 18                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    181       B     225      1                      
REMARK   3           1     A    181       A     225      1                      
REMARK   3           1     C    181       C     225      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  18    B    (A):    623 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  18    A    (A):    623 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  18    C    (A):    623 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     18    B (A**2):    623 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     18    A (A**2):    623 ; 0.060 ; 0.500           
REMARK   3   TIGHT THERMAL     18    C (A**2):    623 ; 0.070 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 19                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    226       B     231      1                      
REMARK   3           1     A    226       A     231      1                      
REMARK   3           1     C    226       C     231      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  19    B    (A):     51 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  19    A    (A):     51 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  19    C    (A):     51 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     19    B (A**2):     51 ; 0.040 ; 0.500           
REMARK   3   TIGHT THERMAL     19    A (A**2):     51 ; 0.070 ; 0.500           
REMARK   3   TIGHT THERMAL     19    C (A**2):     51 ; 0.060 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 20                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    232       B     255      1                      
REMARK   3           1     A    232       A     255      1                      
REMARK   3           1     C    232       C     255      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  20    B    (A):    313 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  20    A    (A):    313 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  20    C    (A):    313 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     20    B (A**2):    313 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     20    A (A**2):    313 ; 0.060 ; 0.500           
REMARK   3   TIGHT THERMAL     20    C (A**2):    313 ; 0.060 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 21                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    256       B     311      1                      
REMARK   3           1     A    256       A     311      1                      
REMARK   3           1     C    256       C     311      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  21    B    (A):    699 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  21    A    (A):    699 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  21    C    (A):    699 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     21    B (A**2):    699 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     21    A (A**2):    699 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     21    C (A**2):    699 ; 0.050 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 22                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    312       B     317      1                      
REMARK   3           1     A    312       A     317      1                      
REMARK   3           1     C    312       C     317      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  22    B    (A):     70 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  22    A    (A):     70 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  22    C    (A):     70 ; 0.010 ; 0.050           
REMARK   3   TIGHT THERMAL     22    B (A**2):     70 ; 0.030 ; 0.500           
REMARK   3   TIGHT THERMAL     22    A (A**2):     70 ; 0.030 ; 0.500           
REMARK   3   TIGHT THERMAL     22    C (A**2):     70 ; 0.030 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 23                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    318       B     327      1                      
REMARK   3           1     A    318       A     327      1                      
REMARK   3           1     C    318       C     327      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  23    B    (A):    132 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  23    A    (A):    132 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  23    C    (A):    132 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     23    B (A**2):    132 ; 0.040 ; 0.500           
REMARK   3   TIGHT THERMAL     23    A (A**2):    132 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     23    C (A**2):    132 ; 0.050 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 24                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    328       B     333      1                      
REMARK   3           1     A    328       A     333      1                      
REMARK   3           1     C    328       C     333      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  24    B    (A):     71 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  24    A    (A):     71 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  24    C    (A):     71 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     24    B (A**2):     71 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     24    A (A**2):     71 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     24    C (A**2):     71 ; 0.050 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 25                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    344       B     350      1                      
REMARK   3           1     A    344       A     350      1                      
REMARK   3           1     C    344       C     350      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  25    B    (A):     86 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  25    A    (A):     86 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  25    C    (A):     86 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     25    B (A**2):     86 ; 0.060 ; 0.500           
REMARK   3   TIGHT THERMAL     25    A (A**2):     86 ; 0.060 ; 0.500           
REMARK   3   TIGHT THERMAL     25    C (A**2):     86 ; 0.050 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 26                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    355       B     394      1                      
REMARK   3           1     A    355       A     394      1                      
REMARK   3           1     C    355       C     394      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  26    B    (A):    558 ; 0.040 ; 0.050           
REMARK   3   TIGHT POSITIONAL  26    A    (A):    558 ; 0.060 ; 0.050           
REMARK   3   TIGHT POSITIONAL  26    C    (A):    558 ; 0.040 ; 0.050           
REMARK   3   TIGHT THERMAL     26    B (A**2):    558 ; 0.060 ; 0.500           
REMARK   3   TIGHT THERMAL     26    A (A**2):    558 ; 0.060 ; 0.500           
REMARK   3   TIGHT THERMAL     26    C (A**2):    558 ; 0.060 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 27                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    395       B     398      1                      
REMARK   3           1     A    395       A     398      1                      
REMARK   3           1     C    395       C     398      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  27    B    (A):     33 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  27    A    (A):     33 ; 0.030 ; 0.050           
REMARK   3   TIGHT POSITIONAL  27    C    (A):     33 ; 0.030 ; 0.050           
REMARK   3   TIGHT THERMAL     27    B (A**2):     33 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     27    A (A**2):     33 ; 0.060 ; 0.500           
REMARK   3   TIGHT THERMAL     27    C (A**2):     33 ; 0.060 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 28                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    399       B     413      1                      
REMARK   3           1     A    399       A     413      1                      
REMARK   3           1     C    399       C     413      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  28    B    (A):    189 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  28    A    (A):    189 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  28    C    (A):    189 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     28    B (A**2):    189 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     28    A (A**2):    189 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     28    C (A**2):    189 ; 0.050 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 29                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    418       B     421      1                      
REMARK   3           1     A    418       A     421      1                      
REMARK   3           1     C    418       C     421      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  29    B    (A):     44 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  29    A    (A):     44 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  29    C    (A):     44 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     29    B (A**2):     44 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     29    A (A**2):     44 ; 0.040 ; 0.500           
REMARK   3   TIGHT THERMAL     29    C (A**2):     44 ; 0.060 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 30                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    435       B     451      1                      
REMARK   3           1     A    435       A     451      1                      
REMARK   3           1     C    435       C     451      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  30    B    (A):    231 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  30    A    (A):    231 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  30    C    (A):    231 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     30    B (A**2):    231 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     30    A (A**2):    231 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     30    C (A**2):    231 ; 0.050 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 31                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    452       B     483      1                      
REMARK   3           1     A    452       A     483      1                      
REMARK   3           1     C    452       C     483      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  31    B    (A):    381 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  31    A    (A):    381 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  31    C    (A):    381 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     31    B (A**2):    381 ; 0.060 ; 0.500           
REMARK   3   TIGHT THERMAL     31    A (A**2):    381 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     31    C (A**2):    381 ; 0.060 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 32                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    515       B     530      1                      
REMARK   3           1     A    515       A     530      1                      
REMARK   3           1     C    515       C     530      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  32    B    (A):    207 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  32    A    (A):    207 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  32    C    (A):    207 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     32    B (A**2):    207 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     32    A (A**2):    207 ; 0.060 ; 0.500           
REMARK   3   TIGHT THERMAL     32    C (A**2):    207 ; 0.070 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 33                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    531       B     549      1                      
REMARK   3           1     A    531       A     549      1                      
REMARK   3           1     C    531       C     549      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  33    B    (A):    261 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  33    A    (A):    261 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  33    C    (A):    261 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     33    B (A**2):    261 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     33    A (A**2):    261 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     33    C (A**2):    261 ; 0.050 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 34                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    561       B     571      1                      
REMARK   3           1     A    561       A     571      1                      
REMARK   3           1     C    561       C     571      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  34    B    (A):    163 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  34    A    (A):    163 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  34    C    (A):    163 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     34    B (A**2):    163 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     34    A (A**2):    163 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     34    C (A**2):    163 ; 0.050 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 35                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    572       B     579      1                      
REMARK   3           1     A    572       A     579      1                      
REMARK   3           1     C    572       C     579      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  35    B    (A):    107 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  35    A    (A):    107 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  35    C    (A):    107 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     35    B (A**2):    107 ; 0.040 ; 0.500           
REMARK   3   TIGHT THERMAL     35    A (A**2):    107 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     35    C (A**2):    107 ; 0.040 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 36                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    580       B     590      1                      
REMARK   3           1     A    580       A     590      1                      
REMARK   3           1     C    580       C     590      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  36    B    (A):    137 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  36    A    (A):    137 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  36    C    (A):    137 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     36    B (A**2):    137 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     36    A (A**2):    137 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     36    C (A**2):    137 ; 0.050 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 37                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    610       B     618      1                      
REMARK   3           1     A    610       A     618      1                      
REMARK   3           1     C    610       C     618      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  37    B    (A):    123 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  37    A    (A):    123 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  37    C    (A):    123 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     37    B (A**2):    123 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     37    A (A**2):    123 ; 0.040 ; 0.500           
REMARK   3   TIGHT THERMAL     37    C (A**2):    123 ; 0.050 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 38                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    619       B     631      1                      
REMARK   3           1     A    619       A     631      1                      
REMARK   3           1     C    619       C     631      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  38    B    (A):    133 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  38    A    (A):    133 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  38    C    (A):    133 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     38    B (A**2):    133 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     38    A (A**2):    133 ; 0.040 ; 0.500           
REMARK   3   TIGHT THERMAL     38    C (A**2):    133 ; 0.040 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 39                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    632       B     647      1                      
REMARK   3           1     A    632       A     647      1                      
REMARK   3           1     C    632       C     647      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  39    B    (A):    200 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  39    A    (A):    200 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  39    C    (A):    200 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     39    B (A**2):    200 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     39    A (A**2):    200 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     39    C (A**2):    200 ; 0.050 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 40                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    648       B     653      1                      
REMARK   3           1     A    648       A     653      1                      
REMARK   3           1     C    648       C     653      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  40    B    (A):     63 ; 0.030 ; 0.050           
REMARK   3   TIGHT POSITIONAL  40    A    (A):     63 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  40    C    (A):     63 ; 0.030 ; 0.050           
REMARK   3   TIGHT THERMAL     40    B (A**2):     63 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     40    A (A**2):     63 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     40    C (A**2):     63 ; 0.040 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 41                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    654       B     667      1                      
REMARK   3           1     A    654       A     667      1                      
REMARK   3           1     C    654       C     667      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  41    B    (A):    165 ; 0.030 ; 0.050           
REMARK   3   TIGHT POSITIONAL  41    A    (A):    165 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  41    C    (A):    165 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     41    B (A**2):    165 ; 0.060 ; 0.500           
REMARK   3   TIGHT THERMAL     41    A (A**2):    165 ; 0.060 ; 0.500           
REMARK   3   TIGHT THERMAL     41    C (A**2):    165 ; 0.050 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 42                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    668       B     672      1                      
REMARK   3           1     A    668       A     672      1                      
REMARK   3           1     C    668       C     672      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  42    B    (A):     53 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  42    A    (A):     53 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  42    C    (A):     53 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     42    B (A**2):     53 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     42    A (A**2):     53 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     42    C (A**2):     53 ; 0.040 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 43                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    673       B     684      1                      
REMARK   3           1     A    673       A     684      1                      
REMARK   3           1     C    673       C     684      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  43    B    (A):    166 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  43    A    (A):    166 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  43    C    (A):    166 ; 0.030 ; 0.050           
REMARK   3   TIGHT THERMAL     43    B (A**2):    166 ; 0.060 ; 0.500           
REMARK   3   TIGHT THERMAL     43    A (A**2):    166 ; 0.060 ; 0.500           
REMARK   3   TIGHT THERMAL     43    C (A**2):    166 ; 0.040 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 44                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    696       B     710      1                      
REMARK   3           1     A    696       A     710      1                      
REMARK   3           1     C    696       C     710      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  44    B    (A):    163 ; 0.060 ; 0.050           
REMARK   3   TIGHT POSITIONAL  44    A    (A):    163 ; 0.110 ; 0.050           
REMARK   3   TIGHT POSITIONAL  44    C    (A):    163 ; 0.060 ; 0.050           
REMARK   3   TIGHT THERMAL     44    B (A**2):    163 ; 0.060 ; 0.500           
REMARK   3   TIGHT THERMAL     44    A (A**2):    163 ; 0.060 ; 0.500           
REMARK   3   TIGHT THERMAL     44    C (A**2):    163 ; 0.040 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 45                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    726       B     735      1                      
REMARK   3           1     A    726       A     735      1                      
REMARK   3           1     C    726       C     735      1                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   TIGHT POSITIONAL  45    B    (A):    121 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  45    A    (A):    121 ; 0.020 ; 0.050           
REMARK   3   TIGHT POSITIONAL  45    C    (A):    121 ; 0.020 ; 0.050           
REMARK   3   TIGHT THERMAL     45    B (A**2):    121 ; 0.050 ; 0.500           
REMARK   3   TIGHT THERMAL     45    A (A**2):    121 ; 0.060 ; 0.500           
REMARK   3   TIGHT THERMAL     45    C (A**2):    121 ; 0.040 ; 0.500           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 46                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    591       B     609      4                      
REMARK   3           1     A    591       A     609      4                      
REMARK   3           1     C    591       C     609      4                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   MEDIUM POSITIONAL 46    B    (A):    249 ; 0.250 ; 0.500           
REMARK   3   MEDIUM POSITIONAL 46    A    (A):    249 ; 0.200 ; 0.500           
REMARK   3   MEDIUM POSITIONAL 46    C    (A):    249 ; 0.190 ; 0.500           
REMARK   3   MEDIUM THERMAL    46    B (A**2):    249 ; 0.640 ; 2.000           
REMARK   3   MEDIUM THERMAL    46    A (A**2):    249 ; 0.680 ; 2.000           
REMARK   3   MEDIUM THERMAL    46    C (A**2):    249 ; 0.670 ; 2.000           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 47                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    800       B     808      4                      
REMARK   3           1     A    800       A     808      4                      
REMARK   3           1     C    800       C     808      4                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   MEDIUM POSITIONAL 47    B    (A):     69 ; 0.260 ; 0.500           
REMARK   3   MEDIUM POSITIONAL 47    A    (A):     69 ; 0.390 ; 0.500           
REMARK   3   MEDIUM POSITIONAL 47    C    (A):     69 ; 0.250 ; 0.500           
REMARK   3   MEDIUM THERMAL    47    B (A**2):     69 ; 0.680 ; 2.000           
REMARK   3   MEDIUM THERMAL    47    A (A**2):     69 ; 0.720 ; 2.000           
REMARK   3   MEDIUM THERMAL    47    C (A**2):     69 ; 0.460 ; 2.000           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 48                                 
REMARK   3     CHAIN NAMES                    : B A C                           
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    915       B     933      4                      
REMARK   3           1     A    915       A     933      4                      
REMARK   3           1     C    915       C     933      4                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   MEDIUM POSITIONAL 48    B    (A):    195 ; 0.250 ; 0.500           
REMARK   3   MEDIUM POSITIONAL 48    A    (A):    195 ; 0.280 ; 0.500           
REMARK   3   MEDIUM POSITIONAL 48    C    (A):    195 ; 0.260 ; 0.500           
REMARK   3   MEDIUM THERMAL    48    B (A**2):    195 ; 0.790 ; 2.000           
REMARK   3   MEDIUM THERMAL    48    A (A**2):    195 ; 0.660 ; 2.000           
REMARK   3   MEDIUM THERMAL    48    C (A**2):    195 ; 0.440 ; 2.000           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 49                                 
REMARK   3     CHAIN NAMES                    : B C                             
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    761       B     788      6                      
REMARK   3           1     C    761       C     788      6                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   LOOSE POSITIONAL  49    B    (A):    322 ; 0.320 ; 5.000           
REMARK   3   LOOSE THERMAL     49    B (A**2):    322 ; 2.680 ;10.000           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 50                                 
REMARK   3     CHAIN NAMES                    : B C                             
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    809       B     815      6                      
REMARK   3           1     C    809       C     815      6                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   LOOSE POSITIONAL  50    B    (A):     76 ; 0.260 ; 5.000           
REMARK   3   LOOSE THERMAL     50    B (A**2):     76 ; 3.580 ;10.000           
REMARK   3                                                                      
REMARK   3  NCS GROUP NUMBER               : 51                                 
REMARK   3     CHAIN NAMES                    : B C                             
REMARK   3     NUMBER OF COMPONENTS NCS GROUP : 1                               
REMARK   3       COMPONENT C  SSSEQI  TO  C   SSSEQI   CODE                     
REMARK   3           1     B    634       B     855      6                      
REMARK   3           1     C    634       C     855      6                      
REMARK   3                   GROUP CHAIN        COUNT   RMS     WEIGHT          
REMARK   3   LOOSE POSITIONAL  51    B    (A):   2450 ; 0.580 ; 5.000           
REMARK   3   LOOSE THERMAL     51    B (A**2):   2450 ; 2.780 ;10.000           
REMARK   3                                                                      
REMARK   3  TLS DETAILS                                                         
REMARK   3   NUMBER OF TLS GROUPS  : NULL                                       
REMARK   3                                                                      
REMARK   3  BULK SOLVENT MODELLING.                                             
REMARK   3   METHOD USED : MASK                                                 
REMARK   3   PARAMETERS FOR MASK CALCULATION                                    
REMARK   3   VDW PROBE RADIUS   : 1.40                                          
REMARK   3   ION PROBE RADIUS   : 0.80                                          
REMARK   3   SHRINKAGE RADIUS   : 0.80                                          
REMARK   3                                                                      
REMARK   3  OTHER REFINEMENT REMARKS: HYDROGENS HAVE BEEN ADDED IN THE RIDING   
REMARK   3  POSITIONS                                                           
REMARK   4                                                                      
REMARK   4 3QNF COMPLIES WITH FORMAT V. 3.30, 13-JUL-11                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 09-FEB-11.                  
REMARK 100 THE DEPOSITION ID IS D_1000063864.                                   
REMARK 200                                                                      
REMARK 200 EXPERIMENTAL DETAILS                                                 
REMARK 200  EXPERIMENT TYPE                : X-RAY DIFFRACTION                  
REMARK 200  DATE OF DATA COLLECTION        : 06-MAR-10                          
REMARK 200  TEMPERATURE           (KELVIN) : 100                                
REMARK 200  PH                             : 7.5                                
REMARK 200  NUMBER OF CRYSTALS USED        : 1                                  
REMARK 200                                                                      
REMARK 200  SYNCHROTRON              (Y/N) : Y                                  
REMARK 200  RADIATION SOURCE               : DIAMOND                            
REMARK 200  BEAMLINE                       : I24                                
REMARK 200  X-RAY GENERATOR MODEL          : NULL                               
REMARK 200  MONOCHROMATIC OR LAUE    (M/L) : M                                  
REMARK 200  WAVELENGTH OR RANGE        (A) : 0.9778                             
REMARK 200  MONOCHROMATOR                  : NULL                               
REMARK 200  OPTICS                         : NULL                               
REMARK 200                                                                      
REMARK 200  DETECTOR TYPE                  : PIXEL                              
REMARK 200  DETECTOR MANUFACTURER          : PSI PILATUS 6M                     
REMARK 200  INTENSITY-INTEGRATION SOFTWARE : XDS                                
REMARK 200  DATA SCALING SOFTWARE          : SCALA                              
REMARK 200                                                                      
REMARK 200  NUMBER OF UNIQUE REFLECTIONS   : 60032                              
REMARK 200  RESOLUTION RANGE HIGH      (A) : 3.000                              
REMARK 200  RESOLUTION RANGE LOW       (A) : 30.000                             
REMARK 200  REJECTION CRITERIA  (SIGMA(I)) : -3.000                             
REMARK 200                                                                      
REMARK 200 OVERALL.                                                             
REMARK 200  COMPLETENESS FOR RANGE     (%) : 97.8                               
REMARK 200  DATA REDUNDANCY                : 3.000                              
REMARK 200  R MERGE                    (I) : 0.15300                            
REMARK 200  R SYM                      (I) : NULL                               
REMARK 200  <I/SIGMA(I)> FOR THE DATA SET  : 5.8000                             
REMARK 200                                                                      
REMARK 200 IN THE HIGHEST RESOLUTION SHELL.                                     
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 3.00                     
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE LOW  (A) : 3.16                     
REMARK 200  COMPLETENESS FOR SHELL     (%) : 98.8                               
REMARK 200  DATA REDUNDANCY IN SHELL       : 3.00                               
REMARK 200  R MERGE FOR SHELL          (I) : 0.66800                            
REMARK 200  R SYM FOR SHELL            (I) : NULL                               
REMARK 200  <I/SIGMA(I)> FOR SHELL         : 1.600                              
REMARK 200                                                                      
REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH                              
REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT        
REMARK 200 SOFTWARE USED: PHASER                                                
REMARK 200 STARTING MODEL: 2XDT                                                 
REMARK 200                                                                      
REMARK 200 REMARK: NULL                                                         
REMARK 280                                                                      
REMARK 280 CRYSTAL                                                              
REMARK 280 SOLVENT CONTENT, VS   (%): 46.66                                     
REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.31                     
REMARK 280                                                                      
REMARK 280 CRYSTALLIZATION CONDITIONS: 0.1M HEPES PH 7.5; 25% PEG 3350, VAPOR   
REMARK 280  DIFFUSION, TEMPERATURE 293K                                         
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY                                            
REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 21 21 21                       
REMARK 290                                                                      
REMARK 290      SYMOP   SYMMETRY                                                
REMARK 290     NNNMMM   OPERATOR                                                
REMARK 290       1555   X,Y,Z                                                   
REMARK 290       2555   -X+1/2,-Y,Z+1/2                                         
REMARK 290       3555   -X,Y+1/2,-Z+1/2                                         
REMARK 290       4555   X+1/2,-Y+1/2,-Z                                         
REMARK 290                                                                      
REMARK 290     WHERE NNN -> OPERATOR NUMBER                                     
REMARK 290           MMM -> TRANSLATION VECTOR                                  
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS                            
REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM             
REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY                
REMARK 290 RELATED MOLECULES.                                                   
REMARK 290   SMTRY1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY1   2 -1.000000  0.000000  0.000000       48.62300            
REMARK 290   SMTRY2   2  0.000000 -1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   2  0.000000  0.000000  1.000000      116.84350            
REMARK 290   SMTRY1   3 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   3  0.000000  1.000000  0.000000       66.40800            
REMARK 290   SMTRY3   3  0.000000  0.000000 -1.000000      116.84350            
REMARK 290   SMTRY1   4  1.000000  0.000000  0.000000       48.62300            
REMARK 290   SMTRY2   4  0.000000 -1.000000  0.000000       66.40800            
REMARK 290   SMTRY3   4  0.000000  0.000000 -1.000000        0.00000            
REMARK 290                                                                      
REMARK 290 REMARK: NULL                                                         
REMARK 300                                                                      
REMARK 300 BIOMOLECULE: 1, 2, 3                                                 
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM                
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN                  
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON               
REMARK 300 BURIED SURFACE AREA.                                                 
REMARK 350                                                                      
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN           
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE                
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS          
REMARK 350 GIVEN BELOW.  BOTH NON-CRYSTALLOGRAPHIC AND                          
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.                               
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 1                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: MONOMERIC                         
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: MONOMERIC                  
REMARK 350 SOFTWARE USED: PISA                                                  
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A                                     
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 2                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: MONOMERIC                         
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: MONOMERIC                  
REMARK 350 SOFTWARE USED: PISA                                                  
REMARK 350 APPLY THE FOLLOWING TO CHAINS: B                                     
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 3                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: MONOMERIC                         
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: MONOMERIC                  
REMARK 350 SOFTWARE USED: PISA                                                  
REMARK 350 APPLY THE FOLLOWING TO CHAINS: C                                     
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 465                                                                      
REMARK 465 MISSING RESIDUES                                                     
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE                       
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)                
REMARK 465                                                                      
REMARK 465   M RES C SSSEQI                                                     
REMARK 465     LEU A    -5                                                      
REMARK 465     ARG A    -4                                                      
REMARK 465     ARG A    -3                                                      
REMARK 465     ARG A    -2                                                      
REMARK 465     TYR A    -1                                                      
REMARK 465     THR A     0                                                      
REMARK 465     MET A     1                                                      
REMARK 465     VAL A     2                                                      
REMARK 465     PHE A     3                                                      
REMARK 465     LEU A     4                                                      
REMARK 465     PRO A     5                                                      
REMARK 465     LEU A     6                                                      
REMARK 465     LYS A     7                                                      
REMARK 465     TRP A     8                                                      
REMARK 465     SER A     9                                                      
REMARK 465     LEU A    10                                                      
REMARK 465     ALA A    11                                                      
REMARK 465     THR A    12                                                      
REMARK 465     MET A    13                                                      
REMARK 465     SER A    14                                                      
REMARK 465     PHE A    15                                                      
REMARK 465     LEU A    16                                                      
REMARK 465     LEU A    17                                                      
REMARK 465     SER A    18                                                      
REMARK 465     SER A    19                                                      
REMARK 465     LEU A    20                                                      
REMARK 465     LEU A    21                                                      
REMARK 465     ALA A    22                                                      
REMARK 465     LEU A    23                                                      
REMARK 465     LEU A    24                                                      
REMARK 465     THR A    25                                                      
REMARK 465     VAL A    26                                                      
REMARK 465     SER A    27                                                      
REMARK 465     THR A    28                                                      
REMARK 465     PRO A    29                                                      
REMARK 465     SER A    30                                                      
REMARK 465     TRP A    31                                                      
REMARK 465     CYS A    32                                                      
REMARK 465     GLN A    33                                                      
REMARK 465     SER A    34                                                      
REMARK 465     THR A    35                                                      
REMARK 465     GLU A    36                                                      
REMARK 465     ALA A    37                                                      
REMARK 465     SER A    38                                                      
REMARK 465     PRO A    39                                                      
REMARK 465     LYS A    40                                                      
REMARK 465     ARG A    41                                                      
REMARK 465     SER A    42                                                      
REMARK 465     ASP A    43                                                      
REMARK 465     GLY A    44                                                      
REMARK 465     THR A    45                                                      
REMARK 465     ALA A   111                                                      
REMARK 465     GLY A   112                                                      
REMARK 465     GLU A   113                                                      
REMARK 465     ARG A   114                                                      
REMARK 465     PRO A   426                                                      
REMARK 465     ALA A   427                                                      
REMARK 465     GLN A   428                                                      
REMARK 465     ILE A   429                                                      
REMARK 465     ARG A   430                                                      
REMARK 465     GLU A   431                                                      
REMARK 465     MET A   432                                                      
REMARK 465     PHE A   433                                                      
REMARK 465     CYS A   486                                                      
REMARK 465     PRO A   487                                                      
REMARK 465     THR A   488                                                      
REMARK 465     ASP A   489                                                      
REMARK 465     GLY A   490                                                      
REMARK 465     VAL A   491                                                      
REMARK 465     LYS A   492                                                      
REMARK 465     GLY A   493                                                      
REMARK 465     MET A   494                                                      
REMARK 465     ASP A   495                                                      
REMARK 465     GLY A   496                                                      
REMARK 465     PHE A   497                                                      
REMARK 465     CYS A   498                                                      
REMARK 465     SER A   499                                                      
REMARK 465     ARG A   500                                                      
REMARK 465     SER A   501                                                      
REMARK 465     GLN A   502                                                      
REMARK 465     HIS A   503                                                      
REMARK 465     SER A   504                                                      
REMARK 465     SER A   505                                                      
REMARK 465     SER A   506                                                      
REMARK 465     SER A   507                                                      
REMARK 465     SER A   508                                                      
REMARK 465     HIS A   509                                                      
REMARK 465     TRP A   510                                                      
REMARK 465     HIS A   511                                                      
REMARK 465     GLN A   512                                                      
REMARK 465     GLU A   513                                                      
REMARK 465     GLY A   514                                                      
REMARK 465     GLY A   552                                                      
REMARK 465     SER A   553                                                      
REMARK 465     ASP A   554                                                      
REMARK 465     GLY A   555                                                      
REMARK 465     ALA A   556                                                      
REMARK 465     PRO A   557                                                      
REMARK 465     ASP A   558                                                      
REMARK 465     ASN A   758                                                      
REMARK 465     GLY A   759                                                      
REMARK 465     ASN A   760                                                      
REMARK 465     LEU A   761                                                      
REMARK 465     SER A   762                                                      
REMARK 465     LEU A   763                                                      
REMARK 465     PRO A   764                                                      
REMARK 465     VAL A   765                                                      
REMARK 465     ASP A   766                                                      
REMARK 465     VAL A   767                                                      
REMARK 465     THR A   768                                                      
REMARK 465     LEU A   769                                                      
REMARK 465     ALA A   770                                                      
REMARK 465     VAL A   771                                                      
REMARK 465     PHE A   772                                                      
REMARK 465     ALA A   773                                                      
REMARK 465     VAL A   774                                                      
REMARK 465     GLY A   775                                                      
REMARK 465     ALA A   776                                                      
REMARK 465     GLN A   777                                                      
REMARK 465     SER A   778                                                      
REMARK 465     THR A   779                                                      
REMARK 465     GLU A   780                                                      
REMARK 465     GLY A   781                                                      
REMARK 465     TRP A   782                                                      
REMARK 465     ASP A   783                                                      
REMARK 465     PHE A   784                                                      
REMARK 465     LEU A   785                                                      
REMARK 465     TYR A   786                                                      
REMARK 465     SER A   787                                                      
REMARK 465     LYS A   788                                                      
REMARK 465     TYR A   789                                                      
REMARK 465     GLN A   790                                                      
REMARK 465     PHE A   791                                                      
REMARK 465     SER A   792                                                      
REMARK 465     LEU A   793                                                      
REMARK 465     SER A   794                                                      
REMARK 465     SER A   795                                                      
REMARK 465     THR A   796                                                      
REMARK 465     GLU A   797                                                      
REMARK 465     LYS A   798                                                      
REMARK 465     SER A   799                                                      
REMARK 465     LYS A   811                                                      
REMARK 465     GLU A   812                                                      
REMARK 465     LYS A   813                                                      
REMARK 465     LEU A   814                                                      
REMARK 465     GLN A   815                                                      
REMARK 465     TRP A   816                                                      
REMARK 465     LEU A   817                                                      
REMARK 465     LEU A   818                                                      
REMARK 465     ASP A   819                                                      
REMARK 465     GLU A   820                                                      
REMARK 465     SER A   821                                                      
REMARK 465     PHE A   822                                                      
REMARK 465     LYS A   823                                                      
REMARK 465     GLY A   824                                                      
REMARK 465     ASP A   825                                                      
REMARK 465     LYS A   826                                                      
REMARK 465     ILE A   827                                                      
REMARK 465     LYS A   828                                                      
REMARK 465     THR A   829                                                      
REMARK 465     GLN A   830                                                      
REMARK 465     GLU A   831                                                      
REMARK 465     PHE A   832                                                      
REMARK 465     PRO A   833                                                      
REMARK 465     GLN A   834                                                      
REMARK 465     ILE A   835                                                      
REMARK 465     LEU A   836                                                      
REMARK 465     THR A   837                                                      
REMARK 465     LEU A   838                                                      
REMARK 465     ILE A   839                                                      
REMARK 465     GLY A   840                                                      
REMARK 465     ARG A   841                                                      
REMARK 465     ASN A   842                                                      
REMARK 465     PRO A   843                                                      
REMARK 465     VAL A   844                                                      
REMARK 465     GLY A   845                                                      
REMARK 465     TYR A   846                                                      
REMARK 465     PRO A   847                                                      
REMARK 465     LEU A   848                                                      
REMARK 465     ALA A   849                                                      
REMARK 465     TRP A   850                                                      
REMARK 465     GLN A   851                                                      
REMARK 465     PHE A   852                                                      
REMARK 465     LEU A   853                                                      
REMARK 465     ARG A   854                                                      
REMARK 465     LYS A   855                                                      
REMARK 465     ASN A   856                                                      
REMARK 465     TRP A   857                                                      
REMARK 465     ASN A   858                                                      
REMARK 465     LYS A   859                                                      
REMARK 465     LEU A   860                                                      
REMARK 465     VAL A   861                                                      
REMARK 465     GLN A   862                                                      
REMARK 465     LYS A   863                                                      
REMARK 465     PHE A   864                                                      
REMARK 465     GLU A   865                                                      
REMARK 465     LEU A   866                                                      
REMARK 465     GLY A   867                                                      
REMARK 465     SER A   868                                                      
REMARK 465     SER A   869                                                      
REMARK 465     SER A   870                                                      
REMARK 465     ILE A   871                                                      
REMARK 465     ALA A   872                                                      
REMARK 465     HIS A   873                                                      
REMARK 465     MET A   874                                                      
REMARK 465     VAL A   875                                                      
REMARK 465     MET A   876                                                      
REMARK 465     GLY A   877                                                      
REMARK 465     THR A   878                                                      
REMARK 465     THR A   879                                                      
REMARK 465     ASN A   880                                                      
REMARK 465     GLN A   881                                                      
REMARK 465     PHE A   882                                                      
REMARK 465     SER A   883                                                      
REMARK 465     THR A   884                                                      
REMARK 465     ARG A   885                                                      
REMARK 465     THR A   886                                                      
REMARK 465     ARG A   887                                                      
REMARK 465     LEU A   888                                                      
REMARK 465     GLU A   889                                                      
REMARK 465     GLU A   890                                                      
REMARK 465     VAL A   891                                                      
REMARK 465     LYS A   892                                                      
REMARK 465     GLY A   893                                                      
REMARK 465     PHE A   894                                                      
REMARK 465     PHE A   895                                                      
REMARK 465     SER A   896                                                      
REMARK 465     SER A   897                                                      
REMARK 465     LEU A   898                                                      
REMARK 465     LYS A   899                                                      
REMARK 465     GLU A   900                                                      
REMARK 465     ASN A   901                                                      
REMARK 465     GLY A   902                                                      
REMARK 465     SER A   903                                                      
REMARK 465     GLN A   904                                                      
REMARK 465     LEU A   905                                                      
REMARK 465     ARG A   906                                                      
REMARK 465     CYS A   907                                                      
REMARK 465     VAL A   908                                                      
REMARK 465     GLN A   909                                                      
REMARK 465     GLN A   910                                                      
REMARK 465     THR A   911                                                      
REMARK 465     ILE A   912                                                      
REMARK 465     GLU A   913                                                      
REMARK 465     THR A   914                                                      
REMARK 465     GLU A   936                                                      
REMARK 465     LYS A   937                                                      
REMARK 465     LEU A   938                                                      
REMARK 465     GLU A   939                                                      
REMARK 465     ARG A   940                                                      
REMARK 465     MET A   941                                                      
REMARK 465     ALA A   942                                                      
REMARK 465     GLU A   943                                                      
REMARK 465     ASN A   944                                                      
REMARK 465     LEU A   945                                                      
REMARK 465     TYR A   946                                                      
REMARK 465     PHE A   947                                                      
REMARK 465     GLN A   948                                                      
REMARK 465     LEU B    -5                                                      
REMARK 465     ARG B    -4                                                      
REMARK 465     ARG B    -3                                                      
REMARK 465     ARG B    -2                                                      
REMARK 465     TYR B    -1                                                      
REMARK 465     THR B     0                                                      
REMARK 465     MET B     1                                                      
REMARK 465     VAL B     2                                                      
REMARK 465     PHE B     3                                                      
REMARK 465     LEU B     4                                                      
REMARK 465     PRO B     5                                                      
REMARK 465     LEU B     6                                                      
REMARK 465     LYS B     7                                                      
REMARK 465     TRP B     8                                                      
REMARK 465     SER B     9                                                      
REMARK 465     LEU B    10                                                      
REMARK 465     ALA B    11                                                      
REMARK 465     THR B    12                                                      
REMARK 465     MET B    13                                                      
REMARK 465     SER B    14                                                      
REMARK 465     PHE B    15                                                      
REMARK 465     LEU B    16                                                      
REMARK 465     LEU B    17                                                      
REMARK 465     SER B    18                                                      
REMARK 465     SER B    19                                                      
REMARK 465     LEU B    20                                                      
REMARK 465     LEU B    21                                                      
REMARK 465     ALA B    22                                                      
REMARK 465     LEU B    23                                                      
REMARK 465     LEU B    24                                                      
REMARK 465     THR B    25                                                      
REMARK 465     VAL B    26                                                      
REMARK 465     SER B    27                                                      
REMARK 465     THR B    28                                                      
REMARK 465     PRO B    29                                                      
REMARK 465     SER B    30                                                      
REMARK 465     TRP B    31                                                      
REMARK 465     CYS B    32                                                      
REMARK 465     GLN B    33                                                      
REMARK 465     SER B    34                                                      
REMARK 465     THR B    35                                                      
REMARK 465     GLU B    36                                                      
REMARK 465     ALA B    37                                                      
REMARK 465     SER B    38                                                      
REMARK 465     PRO B    39                                                      
REMARK 465     LYS B    40                                                      
REMARK 465     ARG B    41                                                      
REMARK 465     SER B    42                                                      
REMARK 465     ASP B    43                                                      
REMARK 465     GLY B    44                                                      
REMARK 465     THR B    45                                                      
REMARK 465     GLY B   110                                                      
REMARK 465     ALA B   111                                                      
REMARK 465     GLY B   112                                                      
REMARK 465     GLU B   113                                                      
REMARK 465     ARG B   114                                                      
REMARK 465     ALA B   427                                                      
REMARK 465     GLN B   428                                                      
REMARK 465     ILE B   429                                                      
REMARK 465     ARG B   430                                                      
REMARK 465     GLU B   431                                                      
REMARK 465     CYS B   486                                                      
REMARK 465     PRO B   487                                                      
REMARK 465     THR B   488                                                      
REMARK 465     ASP B   489                                                      
REMARK 465     GLY B   490                                                      
REMARK 465     VAL B   491                                                      
REMARK 465     LYS B   492                                                      
REMARK 465     GLY B   493                                                      
REMARK 465     MET B   494                                                      
REMARK 465     ASP B   495                                                      
REMARK 465     GLY B   496                                                      
REMARK 465     PHE B   497                                                      
REMARK 465     CYS B   498                                                      
REMARK 465     SER B   499                                                      
REMARK 465     ARG B   500                                                      
REMARK 465     SER B   501                                                      
REMARK 465     GLN B   502                                                      
REMARK 465     HIS B   503                                                      
REMARK 465     SER B   504                                                      
REMARK 465     SER B   505                                                      
REMARK 465     SER B   506                                                      
REMARK 465     SER B   507                                                      
REMARK 465     SER B   508                                                      
REMARK 465     HIS B   509                                                      
REMARK 465     TRP B   510                                                      
REMARK 465     HIS B   511                                                      
REMARK 465     GLN B   512                                                      
REMARK 465     GLU B   513                                                      
REMARK 465     GLY B   514                                                      
REMARK 465     LYS B   551                                                      
REMARK 465     GLY B   552                                                      
REMARK 465     SER B   553                                                      
REMARK 465     ASP B   554                                                      
REMARK 465     GLY B   555                                                      
REMARK 465     ALA B   556                                                      
REMARK 465     PRO B   557                                                      
REMARK 465     ASP B   558                                                      
REMARK 465     SER B   821                                                      
REMARK 465     PHE B   822                                                      
REMARK 465     LYS B   823                                                      
REMARK 465     GLY B   824                                                      
REMARK 465     ASP B   825                                                      
REMARK 465     LYS B   826                                                      
REMARK 465     ILE B   827                                                      
REMARK 465     LYS B   828                                                      
REMARK 465     ASN B   856                                                      
REMARK 465     TRP B   857                                                      
REMARK 465     ASN B   858                                                      
REMARK 465     LYS B   859                                                      
REMARK 465     LEU B   860                                                      
REMARK 465     VAL B   861                                                      
REMARK 465     GLN B   862                                                      
REMARK 465     LYS B   863                                                      
REMARK 465     PHE B   864                                                      
REMARK 465     GLU B   865                                                      
REMARK 465     LEU B   866                                                      
REMARK 465     GLY B   867                                                      
REMARK 465     SER B   868                                                      
REMARK 465     SER B   869                                                      
REMARK 465     SER B   870                                                      
REMARK 465     ILE B   871                                                      
REMARK 465     LYS B   892                                                      
REMARK 465     GLY B   893                                                      
REMARK 465     PHE B   894                                                      
REMARK 465     PHE B   895                                                      
REMARK 465     SER B   896                                                      
REMARK 465     SER B   897                                                      
REMARK 465     LEU B   898                                                      
REMARK 465     LYS B   899                                                      
REMARK 465     GLU B   900                                                      
REMARK 465     ASN B   901                                                      
REMARK 465     GLY B   902                                                      
REMARK 465     SER B   903                                                      
REMARK 465     GLN B   904                                                      
REMARK 465     LEU B   905                                                      
REMARK 465     ARG B   906                                                      
REMARK 465     CYS B   907                                                      
REMARK 465     VAL B   908                                                      
REMARK 465     GLU B   936                                                      
REMARK 465     LYS B   937                                                      
REMARK 465     LEU B   938                                                      
REMARK 465     GLU B   939                                                      
REMARK 465     ARG B   940                                                      
REMARK 465     MET B   941                                                      
REMARK 465     ALA B   942                                                      
REMARK 465     GLU B   943                                                      
REMARK 465     ASN B   944                                                      
REMARK 465     LEU B   945                                                      
REMARK 465     TYR B   946                                                      
REMARK 465     PHE B   947                                                      
REMARK 465     GLN B   948                                                      
REMARK 465     LEU C    -5                                                      
REMARK 465     ARG C    -4                                                      
REMARK 465     ARG C    -3                                                      
REMARK 465     ARG C    -2                                                      
REMARK 465     TYR C    -1                                                      
REMARK 465     THR C     0                                                      
REMARK 465     MET C     1                                                      
REMARK 465     VAL C     2                                                      
REMARK 465     PHE C     3                                                      
REMARK 465     LEU C     4                                                      
REMARK 465     PRO C     5                                                      
REMARK 465     LEU C     6                                                      
REMARK 465     LYS C     7                                                      
REMARK 465     TRP C     8                                                      
REMARK 465     SER C     9                                                      
REMARK 465     LEU C    10                                                      
REMARK 465     ALA C    11                                                      
REMARK 465     THR C    12                                                      
REMARK 465     MET C    13                                                      
REMARK 465     SER C    14                                                      
REMARK 465     PHE C    15                                                      
REMARK 465     LEU C    16                                                      
REMARK 465     LEU C    17                                                      
REMARK 465     SER C    18                                                      
REMARK 465     SER C    19                                                      
REMARK 465     LEU C    20                                                      
REMARK 465     LEU C    21                                                      
REMARK 465     ALA C    22                                                      
REMARK 465     LEU C    23                                                      
REMARK 465     LEU C    24                                                      
REMARK 465     THR C    25                                                      
REMARK 465     VAL C    26                                                      
REMARK 465     SER C    27                                                      
REMARK 465     THR C    28                                                      
REMARK 465     PRO C    29                                                      
REMARK 465     SER C    30                                                      
REMARK 465     TRP C    31                                                      
REMARK 465     CYS C    32                                                      
REMARK 465     GLN C    33                                                      
REMARK 465     SER C    34                                                      
REMARK 465     THR C    35                                                      
REMARK 465     GLU C    36                                                      
REMARK 465     ALA C    37                                                      
REMARK 465     SER C    38                                                      
REMARK 465     PRO C    39                                                      
REMARK 465     LYS C    40                                                      
REMARK 465     ARG C    41                                                      
REMARK 465     SER C    42                                                      
REMARK 465     ASP C    43                                                      
REMARK 465     GLY C    44                                                      
REMARK 465     THR C    45                                                      
REMARK 465     PRO C    46                                                      
REMARK 465     GLY C   112                                                      
REMARK 465     GLU C   113                                                      
REMARK 465     ARG C   114                                                      
REMARK 465     ALA C   427                                                      
REMARK 465     GLN C   428                                                      
REMARK 465     ILE C   429                                                      
REMARK 465     ARG C   430                                                      
REMARK 465     GLU C   431                                                      
REMARK 465     MET C   432                                                      
REMARK 465     PHE C   433                                                      
REMARK 465     ASP C   434                                                      
REMARK 465     CYS C   486                                                      
REMARK 465     PRO C   487                                                      
REMARK 465     THR C   488                                                      
REMARK 465     ASP C   489                                                      
REMARK 465     GLY C   490                                                      
REMARK 465     VAL C   491                                                      
REMARK 465     LYS C   492                                                      
REMARK 465     GLY C   493                                                      
REMARK 465     MET C   494                                                      
REMARK 465     ASP C   495                                                      
REMARK 465     GLY C   496                                                      
REMARK 465     PHE C   497                                                      
REMARK 465     CYS C   498                                                      
REMARK 465     SER C   499                                                      
REMARK 465     ARG C   500                                                      
REMARK 465     SER C   501                                                      
REMARK 465     GLN C   502                                                      
REMARK 465     HIS C   503                                                      
REMARK 465     SER C   504                                                      
REMARK 465     SER C   505                                                      
REMARK 465     SER C   506                                                      
REMARK 465     SER C   507                                                      
REMARK 465     SER C   508                                                      
REMARK 465     HIS C   509                                                      
REMARK 465     TRP C   510                                                      
REMARK 465     HIS C   511                                                      
REMARK 465     GLN C   512                                                      
REMARK 465     GLU C   513                                                      
REMARK 465     GLY C   514                                                      
REMARK 465     GLY C   552                                                      
REMARK 465     SER C   553                                                      
REMARK 465     ASP C   554                                                      
REMARK 465     GLY C   555                                                      
REMARK 465     ALA C   556                                                      
REMARK 465     PRO C   557                                                      
REMARK 465     ASP C   558                                                      
REMARK 465     ASP C   819                                                      
REMARK 465     GLU C   820                                                      
REMARK 465     SER C   821                                                      
REMARK 465     PHE C   822                                                      
REMARK 465     LYS C   823                                                      
REMARK 465     GLY C   824                                                      
REMARK 465     ASP C   825                                                      
REMARK 465     LYS C   826                                                      
REMARK 465     ILE C   827                                                      
REMARK 465     LYS C   828                                                      
REMARK 465     THR C   829                                                      
REMARK 465     GLN C   830                                                      
REMARK 465     GLU C   831                                                      
REMARK 465     PHE C   832                                                      
REMARK 465     PRO C   833                                                      
REMARK 465     ASN C   856                                                      
REMARK 465     TRP C   857                                                      
REMARK 465     ASN C   858                                                      
REMARK 465     LYS C   859                                                      
REMARK 465     LEU C   860                                                      
REMARK 465     VAL C   861                                                      
REMARK 465     GLN C   862                                                      
REMARK 465     LYS C   863                                                      
REMARK 465     PHE C   864                                                      
REMARK 465     GLU C   865                                                      
REMARK 465     LEU C   866                                                      
REMARK 465     GLY C   867                                                      
REMARK 465     SER C   868                                                      
REMARK 465     SER C   869                                                      
REMARK 465     PHE C   894                                                      
REMARK 465     PHE C   895                                                      
REMARK 465     SER C   896                                                      
REMARK 465     SER C   897                                                      
REMARK 465     LEU C   898                                                      
REMARK 465     LYS C   899                                                      
REMARK 465     GLU C   900                                                      
REMARK 465     ASN C   901                                                      
REMARK 465     GLY C   902                                                      
REMARK 465     SER C   903                                                      
REMARK 465     GLN C   904                                                      
REMARK 465     LEU C   905                                                      
REMARK 465     ARG C   906                                                      
REMARK 465     CYS C   907                                                      
REMARK 465     VAL C   908                                                      
REMARK 465     LEU C   938                                                      
REMARK 465     GLU C   939                                                      
REMARK 465     ARG C   940                                                      
REMARK 465     MET C   941                                                      
REMARK 465     ALA C   942                                                      
REMARK 465     GLU C   943                                                      
REMARK 465     ASN C   944                                                      
REMARK 465     LEU C   945                                                      
REMARK 465     TYR C   946                                                      
REMARK 465     PHE C   947                                                      
REMARK 465     GLN C   948                                                      
REMARK 470                                                                      
REMARK 470 MISSING ATOM                                                         
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;           
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;          
REMARK 470 I=INSERTION CODE):                                                   
REMARK 470   M RES CSSEQI  ATOMS                                                
REMARK 470     LYS A  51    CD   CE   NZ                                        
REMARK 470     TRP A  77    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP A  77    CZ3  CH2                                            
REMARK 470     GLN A 101    CG   CD   OE1  NE2                                  
REMARK 470     LYS A 109    CE   NZ                                             
REMARK 470     GLU A 118    CG   CD   OE1  OE2                                  
REMARK 470     ARG A 127    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS A 164    CG   CD   CE   NZ                                   
REMARK 470     SER A 165    OG                                                  
REMARK 470     ARG A 168    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS A 170    CG   CD   CE   NZ                                   
REMARK 470     GLU A 171    CG   CD   OE1  OE2                                  
REMARK 470     LEU A 174    CG   CD1  CD2                                       
REMARK 470     VAL A 227    CG1  CG2                                            
REMARK 470     LYS A 241    NZ                                                  
REMARK 470     LYS A 262    CG   CD   CE   NZ                                   
REMARK 470     LYS A 275    NZ                                                  
REMARK 470     ASP A 335    CG   OD1  OD2                                       
REMARK 470     GLU A 337    CG   CD   OE1  OE2                                  
REMARK 470     LYS A 338    CG   CD   CE   NZ                                   
REMARK 470     SER A 339    OG                                                  
REMARK 470     LYS A 395    CE   NZ                                             
REMARK 470     VAL A 396    CG1  CG2                                            
REMARK 470     LYS A 403    CD   CE   NZ                                        
REMARK 470     GLU A 409    CG   CD   OE1  OE2                                  
REMARK 470     ASN A 414    CG   OD1  ND2                                       
REMARK 470     HIS A 417    CG   ND1  CD2  CE1  NE2                             
REMARK 470     ASP A 434    CG   OD1  OD2                                       
REMARK 470     SER A 453    OG                                                  
REMARK 470     LYS A 458    NZ                                                  
REMARK 470     LYS A 471    NZ                                                  
REMARK 470     LYS A 474    CE   NZ                                             
REMARK 470     ILE A 485    CG1  CG2  CD1                                       
REMARK 470     VAL A 515    CG1  CG2                                            
REMARK 470     LYS A 518    NZ                                                  
REMARK 470     LYS A 528    CE   NZ                                             
REMARK 470     LYS A 545    CE   NZ                                             
REMARK 470     MET A 550    CG   SD   CE                                        
REMARK 470     LYS A 551    CE   NZ                                             
REMARK 470     THR A 559    OG1  CG2                                            
REMARK 470     LYS A 573    NZ                                                  
REMARK 470     LYS A 583    NZ                                                  
REMARK 470     LYS A 585    CG   CD   CE   NZ                                   
REMARK 470     GLU A 596    CG   CD   OE1  OE2                                  
REMARK 470     ASP A 615    CG   OD1  OD2                                       
REMARK 470     LYS A 625    CG   CD   CE   NZ                                   
REMARK 470     SER A 653    OG                                                  
REMARK 470     ILE A 654    CG1  CG2  CD1                                       
REMARK 470     SER A 661    OG                                                  
REMARK 470     LYS A 665    CG   CD   CE   NZ                                   
REMARK 470     ILE A 670    CG1  CG2  CD1                                       
REMARK 470     MET A 671    CG   SD   CE                                        
REMARK 470     LEU A 686    CG   CD1  CD2                                       
REMARK 470     LYS A 689    CG   CD   CE   NZ                                   
REMARK 470     ARG A 690    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP A 691    CG   OD1  OD2                                       
REMARK 470     MET A 692    CG   SD   CE                                        
REMARK 470     ASN A 693    CG   OD1  ND2                                       
REMARK 470     GLU A 694    CG   CD   OE1  OE2                                  
REMARK 470     GLN A 698    CG   CD   OE1  NE2                                  
REMARK 470     LYS A 700    CD   CE   NZ                                        
REMARK 470     ILE A 704    CG1  CG2  CD1                                       
REMARK 470     ARG A 705    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG A 708    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP A 709    CG   OD1  OD2                                       
REMARK 470     LEU A 710    CG   CD1  CD2                                       
REMARK 470     LYS A 713    CG   CD   CE   NZ                                   
REMARK 470     GLN A 714    CD   OE1  NE2                                       
REMARK 470     THR A 715    OG1  CG2                                            
REMARK 470     ASP A 718    CG   OD1  OD2                                       
REMARK 470     GLU A 719    CG   CD   OE1  OE2                                  
REMARK 470     SER A 721    OG                                                  
REMARK 470     VAL A 722    CG1  CG2                                            
REMARK 470     SER A 723    OG                                                  
REMARK 470     GLU A 724    CG   CD   OE1  OE2                                  
REMARK 470     GLN A 730    OE1  NE2                                            
REMARK 470     LEU A 734    CG   CD1  CD2                                       
REMARK 470     ASN A 739    CG   OD1  ND2                                       
REMARK 470     VAL A 744    CG1  CG2                                            
REMARK 470     GLN A 745    CG   CD   OE1  NE2                                  
REMARK 470     ARG A 746    NE   CZ   NH1  NH2                                  
REMARK 470     TYR A 750    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LYS A 753    CG   CD   CE   NZ                                   
REMARK 470     TRP A 754    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP A 754    CZ3  CH2                                            
REMARK 470     LYS A 755    CG   CD   CE   NZ                                   
REMARK 470     GLU A 756    CG   CD   OE1  OE2                                  
REMARK 470     SER A 757    OG                                                  
REMARK 470     GLN A 800    CG   CD   OE1  NE2                                  
REMARK 470     ILE A 801    CG1  CG2  CD1                                       
REMARK 470     GLU A 802    CG   CD   OE1  OE2                                  
REMARK 470     PHE A 803    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     LEU A 805    CG   CD1  CD2                                       
REMARK 470     ARG A 807    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLN A 809    CG   CD   OE1  NE2                                  
REMARK 470     ASN A 810    CG   OD1  ND2                                       
REMARK 470     ILE A 915    CG1  CG2  CD1                                       
REMARK 470     GLU A 916    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 917    CG   CD   OE1  OE2                                  
REMARK 470     ASN A 918    CG   OD1  ND2                                       
REMARK 470     ILE A 919    CG1  CG2  CD1                                       
REMARK 470     MET A 922    CG   SD   CE                                        
REMARK 470     ASP A 923    CG   OD1  OD2                                       
REMARK 470     LYS A 924    CG   CD   CE   NZ                                   
REMARK 470     PHE A 926    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASP A 927    CG   OD1  OD2                                       
REMARK 470     LYS A 928    CG   CD   CE   NZ                                   
REMARK 470     ILE A 929    CG1  CG2  CD1                                       
REMARK 470     VAL A 931    CG1  CG2                                            
REMARK 470     GLN A 934    CG   CD   OE1  NE2                                  
REMARK 470     SER A 935    OG                                                  
REMARK 470     LYS B  51    CD   CE   NZ                                        
REMARK 470     GLN B 101    CG   CD   OE1  NE2                                  
REMARK 470     ARG B 104    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS B 109    CG   CD   CE   NZ                                   
REMARK 470     SER B 116    OG                                                  
REMARK 470     GLU B 124    CG   CD   OE1  OE2                                  
REMARK 470     ARG B 127    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU B 137    CG   CD   OE1  OE2                                  
REMARK 470     LYS B 164    CG   CD   CE   NZ                                   
REMARK 470     ARG B 168    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS B 170    CG   CD   CE   NZ                                   
REMARK 470     GLU B 171    CG   CD   OE1  OE2                                  
REMARK 470     LYS B 206    CE   NZ                                             
REMARK 470     LYS B 223    CE   NZ                                             
REMARK 470     GLU B 229    CG   CD   OE1  OE2                                  
REMARK 470     LYS B 241    NZ                                                  
REMARK 470     LYS B 259    NZ                                                  
REMARK 470     LYS B 262    CG   CD   CE   NZ                                   
REMARK 470     SER B 263    OG                                                  
REMARK 470     LYS B 275    NZ                                                  
REMARK 470     SER B 316    OG                                                  
REMARK 470     GLU B 337    CG   CD   OE1  OE2                                  
REMARK 470     LYS B 338    CG   CD   CE   NZ                                   
REMARK 470     GLU B 367    CG   CD   OE1  OE2                                  
REMARK 470     LYS B 395    CG   CD   CE   NZ                                   
REMARK 470     LYS B 403    CD   CE   NZ                                        
REMARK 470     GLU B 409    CG   CD   OE1  OE2                                  
REMARK 470     ASN B 414    CG   OD1  ND2                                       
REMARK 470     HIS B 417    CG   ND1  CD2  CE1  NE2                             
REMARK 470     GLU B 424    CG   CD   OE1  OE2                                  
REMARK 470     MET B 432    CG   SD   CE                                        
REMARK 470     PHE B 433    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASP B 434    CG   OD1  OD2                                       
REMARK 470     SER B 453    OG                                                  
REMARK 470     LYS B 458    CE   NZ                                             
REMARK 470     ILE B 461    CG1  CG2  CD1                                       
REMARK 470     GLN B 463    CG   CD   OE1  NE2                                  
REMARK 470     LYS B 474    CE   NZ                                             
REMARK 470     ILE B 485    CG1  CG2  CD1                                       
REMARK 470     VAL B 515    CG1  CG2                                            
REMARK 470     LYS B 545    CE   NZ                                             
REMARK 470     THR B 559    OG1  CG2                                            
REMARK 470     LYS B 583    NZ                                                  
REMARK 470     GLU B 593    CG   CD   OE1  OE2                                  
REMARK 470     GLU B 594    CG   CD   OE1  OE2                                  
REMARK 470     LYS B 625    CG   CD   CE   NZ                                   
REMARK 470     LYS B 651    CE   NZ                                             
REMARK 470     LYS B 656    CE   NZ                                             
REMARK 470     LYS B 665    CG   CD   CE   NZ                                   
REMARK 470     ILE B 670    CG1  CG2  CD1                                       
REMARK 470     GLU B 694    CG   CD   OE1  OE2                                  
REMARK 470     ARG B 705    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS B 713    CG   CD   CE   NZ                                   
REMARK 470     GLN B 730    CG   CD   OE1  NE2                                  
REMARK 470     ARG B 752    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS B 755    CG   CD   CE   NZ                                   
REMARK 470     GLU B 756    CG   CD   OE1  OE2                                  
REMARK 470     SER B 757    OG                                                  
REMARK 470     ASN B 758    CG   OD1  ND2                                       
REMARK 470     ASN B 760    CG   OD1  ND2                                       
REMARK 470     LEU B 761    CG   CD1  CD2                                       
REMARK 470     SER B 762    OG                                                  
REMARK 470     GLU B 780    CG   CD   OE1  OE2                                  
REMARK 470     LYS B 788    CE   NZ                                             
REMARK 470     PHE B 791    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     SER B 792    OG                                                  
REMARK 470     LEU B 793    CG   CD1  CD2                                       
REMARK 470     SER B 794    OG                                                  
REMARK 470     SER B 795    OG                                                  
REMARK 470     GLU B 797    CG   CD   OE1  OE2                                  
REMARK 470     LYS B 798    CD   CE   NZ                                        
REMARK 470     GLN B 800    CG   CD   OE1  NE2                                  
REMARK 470     GLU B 802    CG   CD   OE1  OE2                                  
REMARK 470     GLU B 812    CG   CD   OE1  OE2                                  
REMARK 470     LYS B 813    CG   CD   CE   NZ                                   
REMARK 470     GLU B 820    CG   CD   OE1  OE2                                  
REMARK 470     THR B 829    OG1  CG2                                            
REMARK 470     GLN B 830    CG   CD   OE1  NE2                                  
REMARK 470     GLU B 831    CG   CD   OE1  OE2                                  
REMARK 470     GLN B 834    CG   CD   OE1  NE2                                  
REMARK 470     ILE B 835    CG1  CG2  CD1                                       
REMARK 470     ARG B 841    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLN B 851    CG   CD   OE1  NE2                                  
REMARK 470     LYS B 855    CG   CD   CE   NZ                                   
REMARK 470     HIS B 873    CG   ND1  CD2  CE1  NE2                             
REMARK 470     MET B 874    CG   SD   CE                                        
REMARK 470     VAL B 875    CG1  CG2                                            
REMARK 470     ARG B 885    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU B 888    CG   CD1  CD2                                       
REMARK 470     GLU B 889    CG   CD   OE1  OE2                                  
REMARK 470     VAL B 891    CG1  CG2                                            
REMARK 470     GLN B 909    CG   CD   OE1  NE2                                  
REMARK 470     GLN B 910    CG   CD   OE1  NE2                                  
REMARK 470     GLU B 913    CG   CD   OE1  OE2                                  
REMARK 470     GLU B 916    CG   CD   OE1  OE2                                  
REMARK 470     GLU B 917    CG   CD   OE1  OE2                                  
REMARK 470     LYS B 924    CG   CD   CE   NZ                                   
REMARK 470     GLN B 934    CG   CD   OE1  NE2                                  
REMARK 470     ILE C  52    CG1  CG2  CD1                                       
REMARK 470     ILE C  59    CG1  CG2  CD1                                       
REMARK 470     LEU C  71    CG   CD1  CD2                                       
REMARK 470     TRP C  77    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP C  77    CZ3  CH2                                            
REMARK 470     THR C  79    OG1  CG2                                            
REMARK 470     GLN C 101    CG   CD   OE1  NE2                                  
REMARK 470     ILE C 102    CG1  CG2  CD1                                       
REMARK 470     ARG C 104    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS C 109    CG   CD   CE   NZ                                   
REMARK 470     LEU C 115    CG   CD1  CD2                                       
REMARK 470     GLN C 121    CG   CD   OE1  NE2                                  
REMARK 470     VAL C 122    CG1  CG2                                            
REMARK 470     GLU C 124    CG   CD   OE1  OE2                                  
REMARK 470     ARG C 127    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU C 137    CG   CD   OE1  OE2                                  
REMARK 470     HIS C 150    CG   ND1  CD2  CE1  NE2                             
REMARK 470     GLU C 157    CG   CD   OE1  OE2                                  
REMARK 470     LYS C 164    CG   CD   CE   NZ                                   
REMARK 470     LYS C 170    CG   CD   CE   NZ                                   
REMARK 470     GLU C 171    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 173    CG   CD   OE1  OE2                                  
REMARK 470     VAL C 225    CG1  CG2                                            
REMARK 470     VAL C 227    CG1  CG2                                            
REMARK 470     GLU C 229    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 255    CG   CD   OE1  OE2                                  
REMARK 470     LYS C 259    CE   NZ                                             
REMARK 470     LYS C 262    CG   CD   CE   NZ                                   
REMARK 470     LYS C 266    NZ                                                  
REMARK 470     LYS C 275    NZ                                                  
REMARK 470     ASP C 313    CG   OD1  OD2                                       
REMARK 470     SER C 316    OG                                                  
REMARK 470     ARG C 328    NE   CZ   NH1  NH2                                  
REMARK 470     ASP C 335    CG   OD1  OD2                                       
REMARK 470     GLU C 337    CG   CD   OE1  OE2                                  
REMARK 470     LYS C 338    CG   CD   CE   NZ                                   
REMARK 470     SER C 339    OG                                                  
REMARK 470     SER C 340    OG                                                  
REMARK 470     GLU C 367    CG   CD   OE1  OE2                                  
REMARK 470     LYS C 395    NZ                                                  
REMARK 470     LYS C 403    CD   CE   NZ                                        
REMARK 470     GLU C 409    CG   CD   OE1  OE2                                  
REMARK 470     ASN C 414    CG   OD1  ND2                                       
REMARK 470     HIS C 417    CG   ND1  CD2  CE1  NE2                             
REMARK 470     GLU C 424    CG   CD   OE1  OE2                                  
REMARK 470     SER C 453    OG                                                  
REMARK 470     ASP C 455    CG   OD1  OD2                                       
REMARK 470     LYS C 458    NZ                                                  
REMARK 470     LYS C 471    CG   CD   CE   NZ                                   
REMARK 470     LYS C 474    CE   NZ                                             
REMARK 470     GLU C 476    CG   CD   OE1  OE2                                  
REMARK 470     ILE C 485    CG1  CG2  CD1                                       
REMARK 470     VAL C 515    CG1  CG2                                            
REMARK 470     LYS C 528    NZ                                                  
REMARK 470     LYS C 545    CE   NZ                                             
REMARK 470     LYS C 551    CE   NZ                                             
REMARK 470     THR C 559    OG1  CG2                                            
REMARK 470     LYS C 573    NZ                                                  
REMARK 470     ASP C 575    CG   OD1  OD2                                       
REMARK 470     LYS C 585    CG   CD   CE   NZ                                   
REMARK 470     GLU C 593    OE1  OE2                                            
REMARK 470     ASP C 615    CG   OD1  OD2                                       
REMARK 470     LYS C 625    CD   CE   NZ                                        
REMARK 470     LYS C 651    CE   NZ                                             
REMARK 470     SER C 653    OG                                                  
REMARK 470     LYS C 656    CG   CD   CE   NZ                                   
REMARK 470     LYS C 665    CG   CD   CE   NZ                                   
REMARK 470     LYS C 689    CE   NZ                                             
REMARK 470     ASP C 691    CG   OD1  OD2                                       
REMARK 470     ASN C 693    CG   OD1  ND2                                       
REMARK 470     GLU C 694    CG   CD   OE1  OE2                                  
REMARK 470     VAL C 695    CG1  CG2                                            
REMARK 470     ARG C 705    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG C 708    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS C 713    CG   CD   CE   NZ                                   
REMARK 470     VAL C 722    CG1  CG2                                            
REMARK 470     GLN C 741    CG   CD   OE1  NE2                                  
REMARK 470     GLN C 745    CG   CD   OE1  NE2                                  
REMARK 470     GLU C 748    CG   CD   OE1  OE2                                  
REMARK 470     LYS C 753    CG   CD   CE   NZ                                   
REMARK 470     LYS C 755    CD   CE   NZ                                        
REMARK 470     SER C 757    OG                                                  
REMARK 470     ASN C 758    CG   OD1  ND2                                       
REMARK 470     ASN C 760    CG   OD1  ND2                                       
REMARK 470     LEU C 761    CG   CD1  CD2                                       
REMARK 470     SER C 762    OG                                                  
REMARK 470     GLU C 780    CG   CD   OE1  OE2                                  
REMARK 470     SER C 787    OG                                                  
REMARK 470     SER C 792    OG                                                  
REMARK 470     LEU C 793    CG   CD1  CD2                                       
REMARK 470     SER C 794    OG                                                  
REMARK 470     SER C 795    OG                                                  
REMARK 470     THR C 796    OG1  CG2                                            
REMARK 470     GLU C 797    CG   CD   OE1  OE2                                  
REMARK 470     LYS C 798    CG   CD   CE   NZ                                   
REMARK 470     ILE C 801    CG1  CG2  CD1                                       
REMARK 470     ARG C 807    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS C 811    CG   CD   CE   NZ                                   
REMARK 470     GLU C 812    CG   CD   OE1  OE2                                  
REMARK 470     LYS C 813    CG   CD   CE   NZ                                   
REMARK 470     TRP C 816    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP C 816    CZ3  CH2                                            
REMARK 470     LEU C 817    CG   CD1  CD2                                       
REMARK 470     LEU C 818    CG   CD1  CD2                                       
REMARK 470     GLN C 834    CG   CD   OE1  NE2                                  
REMARK 470     ILE C 835    CG1  CG2  CD1                                       
REMARK 470     ARG C 841    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLN C 851    CG   CD   OE1  NE2                                  
REMARK 470     LEU C 853    CG   CD1  CD2                                       
REMARK 470     LYS C 855    CG   CD   CE   NZ                                   
REMARK 470     SER C 870    OG                                                  
REMARK 470     ILE C 871    CG1  CG2  CD1                                       
REMARK 470     MET C 874    CG   SD   CE                                        
REMARK 470     VAL C 875    CG1  CG2                                            
REMARK 470     GLN C 881    CG   CD   OE1  NE2                                  
REMARK 470     SER C 883    OG                                                  
REMARK 470     ARG C 885    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU C 889    CG   CD   OE1  OE2                                  
REMARK 470     LYS C 892    CG   CD   CE   NZ                                   
REMARK 470     GLN C 909    CG   CD   OE1  NE2                                  
REMARK 470     GLU C 913    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 916    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 917    CG   CD   OE1  OE2                                  
REMARK 470     ILE C 919    CG1  CG2  CD1                                       
REMARK 470     LYS C 924    CG   CD   CE   NZ                                   
REMARK 470     SER C 935    OG                                                  
REMARK 470     LYS C 937    CG   CD   CE   NZ                                   
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT                     
REMARK 500                                                                      
REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT.                            
REMARK 500                                                                      
REMARK 500  ATM1  RES C  SSEQI   ATM2  RES C  SSEQI           DISTANCE          
REMARK 500   OE1  GLU B   196     O    HOH B   960              2.09            
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: TORSION ANGLES                                             
REMARK 500                                                                      
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:            
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)                    
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-           
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400            
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        PSI       PHI                                   
REMARK 500    PHE A  47      121.65    -31.57                                   
REMARK 500    ASN A  50       42.04   -151.98                                   
REMARK 500    THR A  90      141.87   -170.04                                   
REMARK 500    GLU A 117       87.40   -166.49                                   
REMARK 500    ASP A 313       42.20    -96.39                                   
REMARK 500    GLU A 320       33.28    -97.50                                   
REMARK 500    LEU A 332      -42.13   -139.31                                   
REMARK 500    GLU A 337      -76.08    -90.77                                   
REMARK 500    TRP A 359      -66.88    -98.82                                   
REMARK 500    HIS A 391       67.24   -119.80                                   
REMARK 500    ASN A 601       63.30     70.48                                   
REMARK 500    ASP A 614     -141.75     55.83                                   
REMARK 500    LYS A 713      -19.14    -48.17                                   
REMARK 500    ASP A 718       42.66   -101.94                                   
REMARK 500    GLU A 719      119.88   -165.83                                   
REMARK 500    HIS A 738        1.12    -62.34                                   
REMARK 500    GLU A 756       81.23    -69.14                                   
REMARK 500    GLN A 809       55.47    -93.24                                   
REMARK 500    ASN B  50       40.61   -150.89                                   
REMARK 500    GLU B 117       86.47   -166.04                                   
REMARK 500    ASP B 313       41.33    -97.97                                   
REMARK 500    GLU B 320       33.15    -96.92                                   
REMARK 500    LEU B 332      -41.77   -137.79                                   
REMARK 500    TRP B 359      -64.73   -100.31                                   
REMARK 500    HIS B 391       66.26   -118.34                                   
REMARK 500    SER B 415       30.88    -85.73                                   
REMARK 500    ASP B 614     -141.44     54.84                                   
REMARK 500    MET B 692       67.53   -164.90                                   
REMARK 500    TRP B 716       75.73   -113.10                                   
REMARK 500    ASN B 739       46.77     38.70                                   
REMARK 500    ASN B 758       22.82     48.95                                   
REMARK 500    PHE B 791       31.76   -145.36                                   
REMARK 500    TRP B 816      -52.42    -26.57                                   
REMARK 500    ASP B 819      -79.55    -70.26                                   
REMARK 500    ARG B 854      -71.04    -70.80                                   
REMARK 500    THR B 879      -29.56   -144.37                                   
REMARK 500    SER B 883      -25.63   -144.00                                   
REMARK 500    GLN B 934       69.78    -66.94                                   
REMARK 500    ASN C  50       41.90   -152.42                                   
REMARK 500    THR C  90      143.09   -171.52                                   
REMARK 500    GLU C 117       85.32   -165.35                                   
REMARK 500    ASP C 313       42.97    -97.10                                   
REMARK 500    GLU C 320       33.76    -97.63                                   
REMARK 500    LEU C 332      -40.42   -138.49                                   
REMARK 500    GLU C 337       49.63    -76.00                                   
REMARK 500    LYS C 338      -44.07   -171.39                                   
REMARK 500    ALA C 341       72.82    -64.85                                   
REMARK 500    TRP C 359      -65.91    -96.99                                   
REMARK 500    HIS C 391       67.43   -118.01                                   
REMARK 500    TYR C 608      144.67   -173.83                                   
REMARK 500                                                                      
REMARK 500 THIS ENTRY HAS      63 RAMACHANDRAN OUTLIERS.                        
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: NON-CIS, NON-TRANS                                         
REMARK 500                                                                      
REMARK 500 THE FOLLOWING PEPTIDE BONDS DEVIATE SIGNIFICANTLY FROM BOTH          
REMARK 500 CIS AND TRANS CONFORMATION.  CIS BONDS, IF ANY, ARE LISTED           
REMARK 500 ON CISPEP RECORDS.  TRANS IS DEFINED AS 180 +/- 30 AND               
REMARK 500 CIS IS DEFINED AS 0 +/- 30 DEGREES.                                  
REMARK 500                                 MODEL     OMEGA                      
REMARK 500 CYS A  736     VAL A  737                   40.72                    
REMARK 500 ALA C  341     SER C  342                  138.20                    
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 620                                                                      
REMARK 620 METAL COORDINATION                                                   
REMARK 620 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 620 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE):                             
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              ZN B5000  ZN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 GLU B 376   OE2                                                    
REMARK 620 2 HIS B 353   NE2  87.5                                              
REMARK 620 3 HIS B 357   NE2 115.1  99.1                                        
REMARK 620 4 GLU B 376   OE1  60.6 146.7  87.2                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              ZN C5000  ZN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 GLU C 376   OE2                                                    
REMARK 620 2 HIS C 353   NE2  81.4                                              
REMARK 620 3 HIS C 357   NE2 110.4  92.1                                        
REMARK 620 4 GLU C 376   OE1  62.4 141.5  89.1                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              ZN A5000  ZN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 GLU A 376   OE2                                                    
REMARK 620 2 HIS A 353   NE2  82.6                                              
REMARK 620 3 HIS A 357   NE2 109.6  93.8                                        
REMARK 620 4 GLU A 376   OE1  61.1 141.2  86.4                                  
REMARK 620 N                    1     2     3                                   
REMARK 800                                                                      
REMARK 800 SITE                                                                 
REMARK 800 SITE_IDENTIFIER: AC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN A 5000                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE NAG A 1001                
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC3                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE NAG A 1002                
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC4                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MAN A 1004                
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC5                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MAN A 1005                
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC6                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN B 5000                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC7                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE NAG B 1154                
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC8                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE NAG B 1070                
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC9                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN C 5000                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: BC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE NAG C 1070                
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: BC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE NAG C 1154                
REMARK 900                                                                      
REMARK 900 RELATED ENTRIES                                                      
REMARK 900 RELATED ID: 2XDT   RELATED DB: PDB                                   
DBREF  3QNF A    1   941  UNP    Q9NZ08   ERAP1_HUMAN      1    941             
DBREF  3QNF B    1   941  UNP    Q9NZ08   ERAP1_HUMAN      1    941             
DBREF  3QNF C    1   941  UNP    Q9NZ08   ERAP1_HUMAN      1    941             
SEQADV 3QNF LEU A   -5  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF ARG A   -4  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF ARG A   -3  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF ARG A   -2  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF TYR A   -1  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF THR A    0  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF ALA A  942  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF GLU A  943  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF ASN A  944  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF LEU A  945  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF TYR A  946  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF PHE A  947  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF GLN A  948  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF LEU B   -5  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF ARG B   -4  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF ARG B   -3  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF ARG B   -2  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF TYR B   -1  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF THR B    0  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF ALA B  942  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF GLU B  943  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF ASN B  944  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF LEU B  945  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF TYR B  946  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF PHE B  947  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF GLN B  948  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF LEU C   -5  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF ARG C   -4  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF ARG C   -3  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF ARG C   -2  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF TYR C   -1  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF THR C    0  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF ALA C  942  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF GLU C  943  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF ASN C  944  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF LEU C  945  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF TYR C  946  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF PHE C  947  UNP  Q9NZ08              EXPRESSION TAG                 
SEQADV 3QNF GLN C  948  UNP  Q9NZ08              EXPRESSION TAG                 
SEQRES   1 A  954  LEU ARG ARG ARG TYR THR MET VAL PHE LEU PRO LEU LYS          
SEQRES   2 A  954  TRP SER LEU ALA THR MET SER PHE LEU LEU SER SER LEU          
SEQRES   3 A  954  LEU ALA LEU LEU THR VAL SER THR PRO SER TRP CYS GLN          
SEQRES   4 A  954  SER THR GLU ALA SER PRO LYS ARG SER ASP GLY THR PRO          
SEQRES   5 A  954  PHE PRO TRP ASN LYS ILE ARG LEU PRO GLU TYR VAL ILE          
SEQRES   6 A  954  PRO VAL HIS TYR ASP LEU LEU ILE HIS ALA ASN LEU THR          
SEQRES   7 A  954  THR LEU THR PHE TRP GLY THR THR LYS VAL GLU ILE THR          
SEQRES   8 A  954  ALA SER GLN PRO THR SER THR ILE ILE LEU HIS SER HIS          
SEQRES   9 A  954  HIS LEU GLN ILE SER ARG ALA THR LEU ARG LYS GLY ALA          
SEQRES  10 A  954  GLY GLU ARG LEU SER GLU GLU PRO LEU GLN VAL LEU GLU          
SEQRES  11 A  954  HIS PRO ARG GLN GLU GLN ILE ALA LEU LEU ALA PRO GLU          
SEQRES  12 A  954  PRO LEU LEU VAL GLY LEU PRO TYR THR VAL VAL ILE HIS          
SEQRES  13 A  954  TYR ALA GLY ASN LEU SER GLU THR PHE HIS GLY PHE TYR          
SEQRES  14 A  954  LYS SER THR TYR ARG THR LYS GLU GLY GLU LEU ARG ILE          
SEQRES  15 A  954  LEU ALA SER THR GLN PHE GLU PRO THR ALA ALA ARG MET          
SEQRES  16 A  954  ALA PHE PRO CYS PHE ASP GLU PRO ALA PHE LYS ALA SER          
SEQRES  17 A  954  PHE SER ILE LYS ILE ARG ARG GLU PRO ARG HIS LEU ALA          
SEQRES  18 A  954  ILE SER ASN MET PRO LEU VAL LYS SER VAL THR VAL ALA          
SEQRES  19 A  954  GLU GLY LEU ILE GLU ASP HIS PHE ASP VAL THR VAL LYS          
SEQRES  20 A  954  MET SER THR TYR LEU VAL ALA PHE ILE ILE SER ASP PHE          
SEQRES  21 A  954  GLU SER VAL SER LYS ILE THR LYS SER GLY VAL LYS VAL          
SEQRES  22 A  954  SER VAL TYR ALA VAL PRO ASP LYS ILE ASN GLN ALA ASP          
SEQRES  23 A  954  TYR ALA LEU ASP ALA ALA VAL THR LEU LEU GLU PHE TYR          
SEQRES  24 A  954  GLU ASP TYR PHE SER ILE PRO TYR PRO LEU PRO LYS GLN          
SEQRES  25 A  954  ASP LEU ALA ALA ILE PRO ASP PHE GLN SER GLY ALA MET          
SEQRES  26 A  954  GLU ASN TRP GLY LEU THR THR TYR ARG GLU SER ALA LEU          
SEQRES  27 A  954  LEU PHE ASP ALA GLU LYS SER SER ALA SER SER LYS LEU          
SEQRES  28 A  954  GLY ILE THR MET THR VAL ALA HIS GLU LEU ALA HIS GLN          
SEQRES  29 A  954  TRP PHE GLY ASN LEU VAL THR MET GLU TRP TRP ASN ASP          
SEQRES  30 A  954  LEU TRP LEU ASN GLU GLY PHE ALA LYS PHE MET GLU PHE          
SEQRES  31 A  954  VAL SER VAL SER VAL THR HIS PRO GLU LEU LYS VAL GLY          
SEQRES  32 A  954  ASP TYR PHE PHE GLY LYS CYS PHE ASP ALA MET GLU VAL          
SEQRES  33 A  954  ASP ALA LEU ASN SER SER HIS PRO VAL SER THR PRO VAL          
SEQRES  34 A  954  GLU ASN PRO ALA GLN ILE ARG GLU MET PHE ASP ASP VAL          
SEQRES  35 A  954  SER TYR ASP LYS GLY ALA CYS ILE LEU ASN MET LEU ARG          
SEQRES  36 A  954  GLU TYR LEU SER ALA ASP ALA PHE LYS SER GLY ILE VAL          
SEQRES  37 A  954  GLN TYR LEU GLN LYS HIS SER TYR LYS ASN THR LYS ASN          
SEQRES  38 A  954  GLU ASP LEU TRP ASP SER MET ALA SER ILE CYS PRO THR          
SEQRES  39 A  954  ASP GLY VAL LYS GLY MET ASP GLY PHE CYS SER ARG SER          
SEQRES  40 A  954  GLN HIS SER SER SER SER SER HIS TRP HIS GLN GLU GLY          
SEQRES  41 A  954  VAL ASP VAL LYS THR MET MET ASN THR TRP THR LEU GLN          
SEQRES  42 A  954  LYS GLY PHE PRO LEU ILE THR ILE THR VAL ARG GLY ARG          
SEQRES  43 A  954  ASN VAL HIS MET LYS GLN GLU HIS TYR MET LYS GLY SER          
SEQRES  44 A  954  ASP GLY ALA PRO ASP THR GLY TYR LEU TRP HIS VAL PRO          
SEQRES  45 A  954  LEU THR PHE ILE THR SER LYS SER ASP MET VAL HIS ARG          
SEQRES  46 A  954  PHE LEU LEU LYS THR LYS THR ASP VAL LEU ILE LEU PRO          
SEQRES  47 A  954  GLU GLU VAL GLU TRP ILE LYS PHE ASN VAL GLY MET ASN          
SEQRES  48 A  954  GLY TYR TYR ILE VAL HIS TYR GLU ASP ASP GLY TRP ASP          
SEQRES  49 A  954  SER LEU THR GLY LEU LEU LYS GLY THR HIS THR ALA VAL          
SEQRES  50 A  954  SER SER ASN ASP ARG ALA SER LEU ILE ASN ASN ALA PHE          
SEQRES  51 A  954  GLN LEU VAL SER ILE GLY LYS LEU SER ILE GLU LYS ALA          
SEQRES  52 A  954  LEU ASP LEU SER LEU TYR LEU LYS HIS GLU THR GLU ILE          
SEQRES  53 A  954  MET PRO VAL PHE GLN GLY LEU ASN GLU LEU ILE PRO MET          
SEQRES  54 A  954  TYR LYS LEU MET GLU LYS ARG ASP MET ASN GLU VAL GLU          
SEQRES  55 A  954  THR GLN PHE LYS ALA PHE LEU ILE ARG LEU LEU ARG ASP          
SEQRES  56 A  954  LEU ILE ASP LYS GLN THR TRP THR ASP GLU GLY SER VAL          
SEQRES  57 A  954  SER GLU ARG MET LEU ARG SER GLN LEU LEU LEU LEU ALA          
SEQRES  58 A  954  CYS VAL HIS ASN TYR GLN PRO CYS VAL GLN ARG ALA GLU          
SEQRES  59 A  954  GLY TYR PHE ARG LYS TRP LYS GLU SER ASN GLY ASN LEU          
SEQRES  60 A  954  SER LEU PRO VAL ASP VAL THR LEU ALA VAL PHE ALA VAL          
SEQRES  61 A  954  GLY ALA GLN SER THR GLU GLY TRP ASP PHE LEU TYR SER          
SEQRES  62 A  954  LYS TYR GLN PHE SER LEU SER SER THR GLU LYS SER GLN          
SEQRES  63 A  954  ILE GLU PHE ALA LEU CYS ARG THR GLN ASN LYS GLU LYS          
SEQRES  64 A  954  LEU GLN TRP LEU LEU ASP GLU SER PHE LYS GLY ASP LYS          
SEQRES  65 A  954  ILE LYS THR GLN GLU PHE PRO GLN ILE LEU THR LEU ILE          
SEQRES  66 A  954  GLY ARG ASN PRO VAL GLY TYR PRO LEU ALA TRP GLN PHE          
SEQRES  67 A  954  LEU ARG LYS ASN TRP ASN LYS LEU VAL GLN LYS PHE GLU          
SEQRES  68 A  954  LEU GLY SER SER SER ILE ALA HIS MET VAL MET GLY THR          
SEQRES  69 A  954  THR ASN GLN PHE SER THR ARG THR ARG LEU GLU GLU VAL          
SEQRES  70 A  954  LYS GLY PHE PHE SER SER LEU LYS GLU ASN GLY SER GLN          
SEQRES  71 A  954  LEU ARG CYS VAL GLN GLN THR ILE GLU THR ILE GLU GLU          
SEQRES  72 A  954  ASN ILE GLY TRP MET ASP LYS ASN PHE ASP LYS ILE ARG          
SEQRES  73 A  954  VAL TRP LEU GLN SER GLU LYS LEU GLU ARG MET ALA GLU          
SEQRES  74 A  954  ASN LEU TYR PHE GLN                                          
SEQRES   1 B  954  LEU ARG ARG ARG TYR THR MET VAL PHE LEU PRO LEU LYS          
SEQRES   2 B  954  TRP SER LEU ALA THR MET SER PHE LEU LEU SER SER LEU          
SEQRES   3 B  954  LEU ALA LEU LEU THR VAL SER THR PRO SER TRP CYS GLN          
SEQRES   4 B  954  SER THR GLU ALA SER PRO LYS ARG SER ASP GLY THR PRO          
SEQRES   5 B  954  PHE PRO TRP ASN LYS ILE ARG LEU PRO GLU TYR VAL ILE          
SEQRES   6 B  954  PRO VAL HIS TYR ASP LEU LEU ILE HIS ALA ASN LEU THR          
SEQRES   7 B  954  THR LEU THR PHE TRP GLY THR THR LYS VAL GLU ILE THR          
SEQRES   8 B  954  ALA SER GLN PRO THR SER THR ILE ILE LEU HIS SER HIS          
SEQRES   9 B  954  HIS LEU GLN ILE SER ARG ALA THR LEU ARG LYS GLY ALA          
SEQRES  10 B  954  GLY GLU ARG LEU SER GLU GLU PRO LEU GLN VAL LEU GLU          
SEQRES  11 B  954  HIS PRO ARG GLN GLU GLN ILE ALA LEU LEU ALA PRO GLU          
SEQRES  12 B  954  PRO LEU LEU VAL GLY LEU PRO TYR THR VAL VAL ILE HIS          
SEQRES  13 B  954  TYR ALA GLY ASN LEU SER GLU THR PHE HIS GLY PHE TYR          
SEQRES  14 B  954  LYS SER THR TYR ARG THR LYS GLU GLY GLU LEU ARG ILE          
SEQRES  15 B  954  LEU ALA SER THR GLN PHE GLU PRO THR ALA ALA ARG MET          
SEQRES  16 B  954  ALA PHE PRO CYS PHE ASP GLU PRO ALA PHE LYS ALA SER          
SEQRES  17 B  954  PHE SER ILE LYS ILE ARG ARG GLU PRO ARG HIS LEU ALA          
SEQRES  18 B  954  ILE SER ASN MET PRO LEU VAL LYS SER VAL THR VAL ALA          
SEQRES  19 B  954  GLU GLY LEU ILE GLU ASP HIS PHE ASP VAL THR VAL LYS          
SEQRES  20 B  954  MET SER THR TYR LEU VAL ALA PHE ILE ILE SER ASP PHE          
SEQRES  21 B  954  GLU SER VAL SER LYS ILE THR LYS SER GLY VAL LYS VAL          
SEQRES  22 B  954  SER VAL TYR ALA VAL PRO ASP LYS ILE ASN GLN ALA ASP          
SEQRES  23 B  954  TYR ALA LEU ASP ALA ALA VAL THR LEU LEU GLU PHE TYR          
SEQRES  24 B  954  GLU ASP TYR PHE SER ILE PRO TYR PRO LEU PRO LYS GLN          
SEQRES  25 B  954  ASP LEU ALA ALA ILE PRO ASP PHE GLN SER GLY ALA MET          
SEQRES  26 B  954  GLU ASN TRP GLY LEU THR THR TYR ARG GLU SER ALA LEU          
SEQRES  27 B  954  LEU PHE ASP ALA GLU LYS SER SER ALA SER SER LYS LEU          
SEQRES  28 B  954  GLY ILE THR MET THR VAL ALA HIS GLU LEU ALA HIS GLN          
SEQRES  29 B  954  TRP PHE GLY ASN LEU VAL THR MET GLU TRP TRP ASN ASP          
SEQRES  30 B  954  LEU TRP LEU ASN GLU GLY PHE ALA LYS PHE MET GLU PHE          
SEQRES  31 B  954  VAL SER VAL SER VAL THR HIS PRO GLU LEU LYS VAL GLY          
SEQRES  32 B  954  ASP TYR PHE PHE GLY LYS CYS PHE ASP ALA MET GLU VAL          
SEQRES  33 B  954  ASP ALA LEU ASN SER SER HIS PRO VAL SER THR PRO VAL          
SEQRES  34 B  954  GLU ASN PRO ALA GLN ILE ARG GLU MET PHE ASP ASP VAL          
SEQRES  35 B  954  SER TYR ASP LYS GLY ALA CYS ILE LEU ASN MET LEU ARG          
SEQRES  36 B  954  GLU TYR LEU SER ALA ASP ALA PHE LYS SER GLY ILE VAL          
SEQRES  37 B  954  GLN TYR LEU GLN LYS HIS SER TYR LYS ASN THR LYS ASN          
SEQRES  38 B  954  GLU ASP LEU TRP ASP SER MET ALA SER ILE CYS PRO THR          
SEQRES  39 B  954  ASP GLY VAL LYS GLY MET ASP GLY PHE CYS SER ARG SER          
SEQRES  40 B  954  GLN HIS SER SER SER SER SER HIS TRP HIS GLN GLU GLY          
SEQRES  41 B  954  VAL ASP VAL LYS THR MET MET ASN THR TRP THR LEU GLN          
SEQRES  42 B  954  LYS GLY PHE PRO LEU ILE THR ILE THR VAL ARG GLY ARG          
SEQRES  43 B  954  ASN VAL HIS MET LYS GLN GLU HIS TYR MET LYS GLY SER          
SEQRES  44 B  954  ASP GLY ALA PRO ASP THR GLY TYR LEU TRP HIS VAL PRO          
SEQRES  45 B  954  LEU THR PHE ILE THR SER LYS SER ASP MET VAL HIS ARG          
SEQRES  46 B  954  PHE LEU LEU LYS THR LYS THR ASP VAL LEU ILE LEU PRO          
SEQRES  47 B  954  GLU GLU VAL GLU TRP ILE LYS PHE ASN VAL GLY MET ASN          
SEQRES  48 B  954  GLY TYR TYR ILE VAL HIS TYR GLU ASP ASP GLY TRP ASP          
SEQRES  49 B  954  SER LEU THR GLY LEU LEU LYS GLY THR HIS THR ALA VAL          
SEQRES  50 B  954  SER SER ASN ASP ARG ALA SER LEU ILE ASN ASN ALA PHE          
SEQRES  51 B  954  GLN LEU VAL SER ILE GLY LYS LEU SER ILE GLU LYS ALA          
SEQRES  52 B  954  LEU ASP LEU SER LEU TYR LEU LYS HIS GLU THR GLU ILE          
SEQRES  53 B  954  MET PRO VAL PHE GLN GLY LEU ASN GLU LEU ILE PRO MET          
SEQRES  54 B  954  TYR LYS LEU MET GLU LYS ARG ASP MET ASN GLU VAL GLU          
SEQRES  55 B  954  THR GLN PHE LYS ALA PHE LEU ILE ARG LEU LEU ARG ASP          
SEQRES  56 B  954  LEU ILE ASP LYS GLN THR TRP THR ASP GLU GLY SER VAL          
SEQRES  57 B  954  SER GLU ARG MET LEU ARG SER GLN LEU LEU LEU LEU ALA          
SEQRES  58 B  954  CYS VAL HIS ASN TYR GLN PRO CYS VAL GLN ARG ALA GLU          
SEQRES  59 B  954  GLY TYR PHE ARG LYS TRP LYS GLU SER ASN GLY ASN LEU          
SEQRES  60 B  954  SER LEU PRO VAL ASP VAL THR LEU ALA VAL PHE ALA VAL          
SEQRES  61 B  954  GLY ALA GLN SER THR GLU GLY TRP ASP PHE LEU TYR SER          
SEQRES  62 B  954  LYS TYR GLN PHE SER LEU SER SER THR GLU LYS SER GLN          
SEQRES  63 B  954  ILE GLU PHE ALA LEU CYS ARG THR GLN ASN LYS GLU LYS          
SEQRES  64 B  954  LEU GLN TRP LEU LEU ASP GLU SER PHE LYS GLY ASP LYS          
SEQRES  65 B  954  ILE LYS THR GLN GLU PHE PRO GLN ILE LEU THR LEU ILE          
SEQRES  66 B  954  GLY ARG ASN PRO VAL GLY TYR PRO LEU ALA TRP GLN PHE          
SEQRES  67 B  954  LEU ARG LYS ASN TRP ASN LYS LEU VAL GLN LYS PHE GLU          
SEQRES  68 B  954  LEU GLY SER SER SER ILE ALA HIS MET VAL MET GLY THR          
SEQRES  69 B  954  THR ASN GLN PHE SER THR ARG THR ARG LEU GLU GLU VAL          
SEQRES  70 B  954  LYS GLY PHE PHE SER SER LEU LYS GLU ASN GLY SER GLN          
SEQRES  71 B  954  LEU ARG CYS VAL GLN GLN THR ILE GLU THR ILE GLU GLU          
SEQRES  72 B  954  ASN ILE GLY TRP MET ASP LYS ASN PHE ASP LYS ILE ARG          
SEQRES  73 B  954  VAL TRP LEU GLN SER GLU LYS LEU GLU ARG MET ALA GLU          
SEQRES  74 B  954  ASN LEU TYR PHE GLN                                          
SEQRES   1 C  954  LEU ARG ARG ARG TYR THR MET VAL PHE LEU PRO LEU LYS          
SEQRES   2 C  954  TRP SER LEU ALA THR MET SER PHE LEU LEU SER SER LEU          
SEQRES   3 C  954  LEU ALA LEU LEU THR VAL SER THR PRO SER TRP CYS GLN          
SEQRES   4 C  954  SER THR GLU ALA SER PRO LYS ARG SER ASP GLY THR PRO          
SEQRES   5 C  954  PHE PRO TRP ASN LYS ILE ARG LEU PRO GLU TYR VAL ILE          
SEQRES   6 C  954  PRO VAL HIS TYR ASP LEU LEU ILE HIS ALA ASN LEU THR          
SEQRES   7 C  954  THR LEU THR PHE TRP GLY THR THR LYS VAL GLU ILE THR          
SEQRES   8 C  954  ALA SER GLN PRO THR SER THR ILE ILE LEU HIS SER HIS          
SEQRES   9 C  954  HIS LEU GLN ILE SER ARG ALA THR LEU ARG LYS GLY ALA          
SEQRES  10 C  954  GLY GLU ARG LEU SER GLU GLU PRO LEU GLN VAL LEU GLU          
SEQRES  11 C  954  HIS PRO ARG GLN GLU GLN ILE ALA LEU LEU ALA PRO GLU          
SEQRES  12 C  954  PRO LEU LEU VAL GLY LEU PRO TYR THR VAL VAL ILE HIS          
SEQRES  13 C  954  TYR ALA GLY ASN LEU SER GLU THR PHE HIS GLY PHE TYR          
SEQRES  14 C  954  LYS SER THR TYR ARG THR LYS GLU GLY GLU LEU ARG ILE          
SEQRES  15 C  954  LEU ALA SER THR GLN PHE GLU PRO THR ALA ALA ARG MET          
SEQRES  16 C  954  ALA PHE PRO CYS PHE ASP GLU PRO ALA PHE LYS ALA SER          
SEQRES  17 C  954  PHE SER ILE LYS ILE ARG ARG GLU PRO ARG HIS LEU ALA          
SEQRES  18 C  954  ILE SER ASN MET PRO LEU VAL LYS SER VAL THR VAL ALA          
SEQRES  19 C  954  GLU GLY LEU ILE GLU ASP HIS PHE ASP VAL THR VAL LYS          
SEQRES  20 C  954  MET SER THR TYR LEU VAL ALA PHE ILE ILE SER ASP PHE          
SEQRES  21 C  954  GLU SER VAL SER LYS ILE THR LYS SER GLY VAL LYS VAL          
SEQRES  22 C  954  SER VAL TYR ALA VAL PRO ASP LYS ILE ASN GLN ALA ASP          
SEQRES  23 C  954  TYR ALA LEU ASP ALA ALA VAL THR LEU LEU GLU PHE TYR          
SEQRES  24 C  954  GLU ASP TYR PHE SER ILE PRO TYR PRO LEU PRO LYS GLN          
SEQRES  25 C  954  ASP LEU ALA ALA ILE PRO ASP PHE GLN SER GLY ALA MET          
SEQRES  26 C  954  GLU ASN TRP GLY LEU THR THR TYR ARG GLU SER ALA LEU          
SEQRES  27 C  954  LEU PHE ASP ALA GLU LYS SER SER ALA SER SER LYS LEU          
SEQRES  28 C  954  GLY ILE THR MET THR VAL ALA HIS GLU LEU ALA HIS GLN          
SEQRES  29 C  954  TRP PHE GLY ASN LEU VAL THR MET GLU TRP TRP ASN ASP          
SEQRES  30 C  954  LEU TRP LEU ASN GLU GLY PHE ALA LYS PHE MET GLU PHE          
SEQRES  31 C  954  VAL SER VAL SER VAL THR HIS PRO GLU LEU LYS VAL GLY          
SEQRES  32 C  954  ASP TYR PHE PHE GLY LYS CYS PHE ASP ALA MET GLU VAL          
SEQRES  33 C  954  ASP ALA LEU ASN SER SER HIS PRO VAL SER THR PRO VAL          
SEQRES  34 C  954  GLU ASN PRO ALA GLN ILE ARG GLU MET PHE ASP ASP VAL          
SEQRES  35 C  954  SER TYR ASP LYS GLY ALA CYS ILE LEU ASN MET LEU ARG          
SEQRES  36 C  954  GLU TYR LEU SER ALA ASP ALA PHE LYS SER GLY ILE VAL          
SEQRES  37 C  954  GLN TYR LEU GLN LYS HIS SER TYR LYS ASN THR LYS ASN          
SEQRES  38 C  954  GLU ASP LEU TRP ASP SER MET ALA SER ILE CYS PRO THR          
SEQRES  39 C  954  ASP GLY VAL LYS GLY MET ASP GLY PHE CYS SER ARG SER          
SEQRES  40 C  954  GLN HIS SER SER SER SER SER HIS TRP HIS GLN GLU GLY          
SEQRES  41 C  954  VAL ASP VAL LYS THR MET MET ASN THR TRP THR LEU GLN          
SEQRES  42 C  954  LYS GLY PHE PRO LEU ILE THR ILE THR VAL ARG GLY ARG          
SEQRES  43 C  954  ASN VAL HIS MET LYS GLN GLU HIS TYR MET LYS GLY SER          
SEQRES  44 C  954  ASP GLY ALA PRO ASP THR GLY TYR LEU TRP HIS VAL PRO          
SEQRES  45 C  954  LEU THR PHE ILE THR SER LYS SER ASP MET VAL HIS ARG          
SEQRES  46 C  954  PHE LEU LEU LYS THR LYS THR ASP VAL LEU ILE LEU PRO          
SEQRES  47 C  954  GLU GLU VAL GLU TRP ILE LYS PHE ASN VAL GLY MET ASN          
SEQRES  48 C  954  GLY TYR TYR ILE VAL HIS TYR GLU ASP ASP GLY TRP ASP          
SEQRES  49 C  954  SER LEU THR GLY LEU LEU LYS GLY THR HIS THR ALA VAL          
SEQRES  50 C  954  SER SER ASN ASP ARG ALA SER LEU ILE ASN ASN ALA PHE          
SEQRES  51 C  954  GLN LEU VAL SER ILE GLY LYS LEU SER ILE GLU LYS ALA          
SEQRES  52 C  954  LEU ASP LEU SER LEU TYR LEU LYS HIS GLU THR GLU ILE          
SEQRES  53 C  954  MET PRO VAL PHE GLN GLY LEU ASN GLU LEU ILE PRO MET          
SEQRES  54 C  954  TYR LYS LEU MET GLU LYS ARG ASP MET ASN GLU VAL GLU          
SEQRES  55 C  954  THR GLN PHE LYS ALA PHE LEU ILE ARG LEU LEU ARG ASP          
SEQRES  56 C  954  LEU ILE ASP LYS GLN THR TRP THR ASP GLU GLY SER VAL          
SEQRES  57 C  954  SER GLU ARG MET LEU ARG SER GLN LEU LEU LEU LEU ALA          
SEQRES  58 C  954  CYS VAL HIS ASN TYR GLN PRO CYS VAL GLN ARG ALA GLU          
SEQRES  59 C  954  GLY TYR PHE ARG LYS TRP LYS GLU SER ASN GLY ASN LEU          
SEQRES  60 C  954  SER LEU PRO VAL ASP VAL THR LEU ALA VAL PHE ALA VAL          
SEQRES  61 C  954  GLY ALA GLN SER THR GLU GLY TRP ASP PHE LEU TYR SER          
SEQRES  62 C  954  LYS TYR GLN PHE SER LEU SER SER THR GLU LYS SER GLN          
SEQRES  63 C  954  ILE GLU PHE ALA LEU CYS ARG THR GLN ASN LYS GLU LYS          
SEQRES  64 C  954  LEU GLN TRP LEU LEU ASP GLU SER PHE LYS GLY ASP LYS          
SEQRES  65 C  954  ILE LYS THR GLN GLU PHE PRO GLN ILE LEU THR LEU ILE          
SEQRES  66 C  954  GLY ARG ASN PRO VAL GLY TYR PRO LEU ALA TRP GLN PHE          
SEQRES  67 C  954  LEU ARG LYS ASN TRP ASN LYS LEU VAL GLN LYS PHE GLU          
SEQRES  68 C  954  LEU GLY SER SER SER ILE ALA HIS MET VAL MET GLY THR          
SEQRES  69 C  954  THR ASN GLN PHE SER THR ARG THR ARG LEU GLU GLU VAL          
SEQRES  70 C  954  LYS GLY PHE PHE SER SER LEU LYS GLU ASN GLY SER GLN          
SEQRES  71 C  954  LEU ARG CYS VAL GLN GLN THR ILE GLU THR ILE GLU GLU          
SEQRES  72 C  954  ASN ILE GLY TRP MET ASP LYS ASN PHE ASP LYS ILE ARG          
SEQRES  73 C  954  VAL TRP LEU GLN SER GLU LYS LEU GLU ARG MET ALA GLU          
SEQRES  74 C  954  ASN LEU TYR PHE GLN                                          
MODRES 3QNF ASN A   70  ASN  GLYCOSYLATION SITE                                 
MODRES 3QNF ASN B   70  ASN  GLYCOSYLATION SITE                                 
MODRES 3QNF ASN B  154  ASN  GLYCOSYLATION SITE                                 
MODRES 3QNF ASN C  154  ASN  GLYCOSYLATION SITE                                 
MODRES 3QNF ASN C   70  ASN  GLYCOSYLATION SITE                                 
HET     ZN  A5000       1                                                       
HET    NAG  A1001      14                                                       
HET    NAG  A1002      14                                                       
HET    MAN  A1004      11                                                       
HET    MAN  A1005      11                                                       
HET     ZN  B5000       1                                                       
HET    NAG  B1154      14                                                       
HET    NAG  B1070      14                                                       
HET     ZN  C5000       1                                                       
HET    NAG  C1070      14                                                       
HET    NAG  C1154      14                                                       
HETNAM      ZN ZINC ION                                                         
HETNAM     NAG N-ACETYL-D-GLUCOSAMINE                                           
HETNAM     MAN ALPHA-D-MANNOSE                                                  
FORMUL   4   ZN    3(ZN 2+)                                                     
FORMUL   5  NAG    6(C8 H15 N O6)                                               
FORMUL   5  MAN    2(C6 H12 O6)                                                 
FORMUL  12  HOH   *39(H2 O)                                                     
HELIX    1   1 PRO A  126  GLN A  128  5                                   3    
HELIX    2   2 ALA A  186  ALA A  190  5                                   5    
HELIX    3   3 SER A  243  VAL A  247  5                                   5    
HELIX    4   4 LYS A  275  GLN A  278  5                                   4    
HELIX    5   5 ALA A  279  SER A  298  1                                  20    
HELIX    6   6 SER A  330  LEU A  332  5                                   3    
HELIX    7   7 SER A  342  PHE A  360  1                                  19    
HELIX    8   8 TRP A  368  ASN A  370  5                                   3    
HELIX    9   9 ASP A  371  HIS A  391  1                                  21    
HELIX   10  10 PRO A  392  LEU A  394  5                                   3    
HELIX   11  11 LYS A  395  ALA A  412  1                                  18    
HELIX   12  12 ASP A  435  LEU A  452  1                                  18    
HELIX   13  13 SER A  453  HIS A  468  1                                  16    
HELIX   14  14 LYS A  474  ALA A  483  1                                  10    
HELIX   15  15 ASP A  516  GLN A  527  1                                  12    
HELIX   16  16 VAL A  602  ASN A  605  5                                   4    
HELIX   17  17 ASP A  615  HIS A  628  1                                  14    
HELIX   18  18 THR A  629  VAL A  631  5                                   3    
HELIX   19  19 SER A  632  ILE A  649  1                                  18    
HELIX   20  20 SER A  653  LEU A  662  1                                  10    
HELIX   21  21 TYR A  663  GLU A  667  5                                   5    
HELIX   22  22 GLU A  669  ARG A  690  1                                  22    
HELIX   23  23 MET A  692  GLN A  714  1                                  23    
HELIX   24  24 SER A  723  CYS A  736  1                                  14    
HELIX   25  25 PRO A  742  TRP A  754  1                                  13    
HELIX   26  26 GLN A  800  ARG A  807  1                                   8    
HELIX   27  27 ILE A  915  SER A  935  1                                  21    
HELIX   28  28 PRO B  126  GLN B  128  5                                   3    
HELIX   29  29 ALA B  186  ALA B  190  5                                   5    
HELIX   30  30 SER B  243  VAL B  247  5                                   5    
HELIX   31  31 LYS B  275  GLN B  278  5                                   4    
HELIX   32  32 ALA B  279  SER B  298  1                                  20    
HELIX   33  33 SER B  330  LEU B  332  5                                   3    
HELIX   34  34 SER B  342  GLN B  358  1                                  17    
HELIX   35  35 TRP B  368  ASN B  370  5                                   3    
HELIX   36  36 ASP B  371  HIS B  391  1                                  21    
HELIX   37  37 PRO B  392  LEU B  394  5                                   3    
HELIX   38  38 LYS B  395  ALA B  412  1                                  18    
HELIX   39  39 ASP B  435  LEU B  452  1                                  18    
HELIX   40  40 SER B  453  HIS B  468  1                                  16    
HELIX   41  41 LYS B  474  ALA B  483  1                                  10    
HELIX   42  42 ASP B  516  GLN B  527  1                                  12    
HELIX   43  43 VAL B  602  ASN B  605  5                                   4    
HELIX   44  44 ASP B  615  HIS B  628  1                                  14    
HELIX   45  45 THR B  629  VAL B  631  5                                   3    
HELIX   46  46 SER B  632  ILE B  649  1                                  18    
HELIX   47  47 SER B  653  LEU B  662  1                                  10    
HELIX   48  48 TYR B  663  GLU B  667  5                                   5    
HELIX   49  49 GLU B  669  GLU B  688  1                                  20    
HELIX   50  50 MET B  692  GLN B  714  1                                  23    
HELIX   51  51 SER B  721  HIS B  738  1                                  18    
HELIX   52  52 TYR B  740  SER B  757  1                                  18    
HELIX   53  53 PRO B  764  ALA B  776  1                                  13    
HELIX   54  54 THR B  779  LYS B  788  1                                  10    
HELIX   55  55 SER B  794  ARG B  807  1                                  14    
HELIX   56  56 ASN B  810  GLU B  820  1                                  11    
HELIX   57  57 GLU B  831  ASN B  842  1                                  12    
HELIX   58  58 GLY B  845  LYS B  855  1                                  11    
HELIX   59  59 THR B  884  VAL B  891  1                                   8    
HELIX   60  60 GLN B  909  GLN B  934  1                                  26    
HELIX   61  61 PRO C  126  GLN C  128  5                                   3    
HELIX   62  62 ALA C  186  ALA C  190  5                                   5    
HELIX   63  63 SER C  243  VAL C  247  5                                   5    
HELIX   64  64 LYS C  275  GLN C  278  5                                   4    
HELIX   65  65 ALA C  279  SER C  298  1                                  20    
HELIX   66  66 SER C  330  LEU C  332  5                                   3    
HELIX   67  67 SER C  343  PHE C  360  1                                  18    
HELIX   68  68 TRP C  368  ASN C  370  5                                   3    
HELIX   69  69 ASP C  371  HIS C  391  1                                  21    
HELIX   70  70 PRO C  392  LEU C  394  5                                   3    
HELIX   71  71 LYS C  395  ALA C  412  1                                  18    
HELIX   72  72 ASP C  435  LEU C  452  1                                  18    
HELIX   73  73 SER C  453  HIS C  468  1                                  16    
HELIX   74  74 LYS C  474  ALA C  483  1                                  10    
HELIX   75  75 ASP C  516  GLN C  527  1                                  12    
HELIX   76  76 VAL C  602  ASN C  605  5                                   4    
HELIX   77  77 ASP C  615  HIS C  628  1                                  14    
HELIX   78  78 THR C  629  VAL C  631  5                                   3    
HELIX   79  79 SER C  632  ILE C  649  1                                  18    
HELIX   80  80 SER C  653  LEU C  662  1                                  10    
HELIX   81  81 TYR C  663  GLU C  667  5                                   5    
HELIX   82  82 GLU C  669  GLU C  688  1                                  20    
HELIX   83  83 MET C  692  LYS C  713  1                                  22    
HELIX   84  84 SER C  721  HIS C  738  1                                  18    
HELIX   85  85 TYR C  740  SER C  757  1                                  18    
HELIX   86  86 PRO C  764  ALA C  776  1                                  13    
HELIX   87  87 SER C  778  PHE C  791  1                                  14    
HELIX   88  88 SER C  795  ARG C  807  1                                  13    
HELIX   89  89 ASN C  810  LEU C  818  1                                   9    
HELIX   90  90 GLN C  834  ASN C  842  1                                   9    
HELIX   91  91 GLY C  845  LYS C  855  1                                  11    
HELIX   92  92 HIS C  873  THR C  878  1                                   6    
HELIX   93  93 THR C  884  LYS C  892  1                                   9    
HELIX   94  94 THR C  911  LYS C  937  1                                  27    
SHEET    1   A 8 SER A 116  PRO A 119  0                                        
SHEET    2   A 8 GLN A 101  LYS A 109 -1  N  LEU A 107   O  GLU A 118           
SHEET    3   A 8 PRO A 144  ASN A 154 -1  O  THR A 146   N  ARG A 108           
SHEET    4   A 8 THR A  75  ALA A  86 -1  N  ILE A  84   O  TYR A 145           
SHEET    5   A 8 VAL A  58  ASN A  70 -1  N  ASN A  70   O  THR A  75           
SHEET    6   A 8 SER A 202  ARG A 209  1  O  SER A 204   N  LEU A  65           
SHEET    7   A 8 LEU A 231  PHE A 236 -1  O  ASP A 234   N  ILE A 207           
SHEET    8   A 8 LEU A 221  ALA A 228 -1  N  VAL A 225   O  GLU A 233           
SHEET    1   B 3 THR A  90  HIS A  96  0                                        
SHEET    2   B 3 GLN A 130  LEU A 139 -1  O  LEU A 139   N  THR A  90           
SHEET    3   B 3 GLN A 121  HIS A 125 -1  N  LEU A 123   O  ALA A 132           
SHEET    1   C 2 GLY A 161  ARG A 168  0                                        
SHEET    2   C 2 LEU A 174  GLN A 181 -1  O  SER A 179   N  TYR A 163           
SHEET    1   D 2 LEU A 214  SER A 217  0                                        
SHEET    2   D 2 PHE A 249  SER A 252 -1  O  SER A 252   N  LEU A 214           
SHEET    1   E 5 GLU A 255  ILE A 260  0                                        
SHEET    2   E 5 LYS A 266  ALA A 271 -1  O  VAL A 267   N  LYS A 259           
SHEET    3   E 5 LYS A 305  ILE A 311  1  O  LEU A 308   N  SER A 268           
SHEET    4   E 5 LEU A 324  ARG A 328  1  O  TYR A 327   N  ALA A 309           
SHEET    5   E 5 ALA A 318  MET A 319 -1  N  MET A 319   O  THR A 326           
SHEET    1   F 2 VAL A 364  MET A 366  0                                        
SHEET    2   F 2 LYS A 471  THR A 473  1  O  THR A 473   N  THR A 365           
SHEET    1   G 4 THR A 586  ILE A 590  0                                        
SHEET    2   G 4 ASN A 541  HIS A 548 -1  N  MET A 544   O  ASP A 587           
SHEET    3   G 4 PRO A 531  ARG A 538 -1  N  LEU A 532   O  GLU A 547           
SHEET    4   G 4 ILE A 609  TYR A 612  1  O  HIS A 611   N  ILE A 533           
SHEET    1   H 3 HIS A 578  LEU A 582  0                                        
SHEET    2   H 3 VAL A 565  THR A 571 -1  N  VAL A 565   O  LEU A 582           
SHEET    3   H 3 ILE A 598  PHE A 600 -1  O  LYS A 599   N  ILE A 570           
SHEET    1   I10 THR B  90  HIS B  96  0                                        
SHEET    2   I10 GLN B 130  LEU B 139 -1  O  ALA B 135   N  SER B  91           
SHEET    3   I10 GLU B 117  HIS B 125 -1  N  LEU B 123   O  ALA B 132           
SHEET    4   I10 GLN B 101  ARG B 108 -1  N  LEU B 107   O  GLU B 118           
SHEET    5   I10 PRO B 144  ASN B 154 -1  O  THR B 146   N  ARG B 108           
SHEET    6   I10 THR B  75  ALA B  86 -1  N  ILE B  84   O  TYR B 145           
SHEET    7   I10 VAL B  58  ASN B  70 -1  N  ASP B  64   O  LYS B  81           
SHEET    8   I10 SER B 202  ARG B 209  1  O  SER B 204   N  LEU B  65           
SHEET    9   I10 LEU B 231  PHE B 236 -1  O  ASP B 234   N  ILE B 207           
SHEET   10   I10 LEU B 221  ALA B 228 -1  N  LYS B 223   O  HIS B 235           
SHEET    1   J 2 GLY B 161  ARG B 168  0                                        
SHEET    2   J 2 LEU B 174  GLN B 181 -1  O  SER B 179   N  TYR B 163           
SHEET    1   K 2 LEU B 214  SER B 217  0                                        
SHEET    2   K 2 PHE B 249  SER B 252 -1  O  SER B 252   N  LEU B 214           
SHEET    1   L 5 GLU B 255  ILE B 260  0                                        
SHEET    2   L 5 LYS B 266  ALA B 271 -1  O  VAL B 267   N  LYS B 259           
SHEET    3   L 5 LYS B 305  ILE B 311  1  O  LEU B 308   N  SER B 268           
SHEET    4   L 5 LEU B 324  ARG B 328  1  O  TYR B 327   N  ALA B 309           
SHEET    5   L 5 ALA B 318  MET B 319 -1  N  MET B 319   O  THR B 326           
SHEET    1   M 2 THR B 365  MET B 366  0                                        
SHEET    2   M 2 ASN B 472  THR B 473  1  O  THR B 473   N  THR B 365           
SHEET    1   N 4 THR B 586  ILE B 590  0                                        
SHEET    2   N 4 ASN B 541  HIS B 548 -1  N  VAL B 542   O  LEU B 589           
SHEET    3   N 4 PRO B 531  ARG B 538 -1  N  LEU B 532   O  GLU B 547           
SHEET    4   N 4 ILE B 609  TYR B 612  1  O  HIS B 611   N  ILE B 533           
SHEET    1   O 3 HIS B 578  LEU B 582  0                                        
SHEET    2   O 3 VAL B 565  THR B 571 -1  N  LEU B 567   O  PHE B 580           
SHEET    3   O 3 ILE B 598  PHE B 600 -1  O  LYS B 599   N  ILE B 570           
SHEET    1   P10 THR C  90  HIS C  96  0                                        
SHEET    2   P10 GLN C 130  LEU C 139 -1  O  ALA C 135   N  SER C  91           
SHEET    3   P10 SER C 116  HIS C 125 -1  N  LEU C 123   O  ALA C 132           
SHEET    4   P10 GLN C 101  LYS C 109 -1  N  ALA C 105   O  LEU C 120           
SHEET    5   P10 PRO C 144  ASN C 154 -1  O  THR C 146   N  ARG C 108           
SHEET    6   P10 THR C  75  ALA C  86 -1  N  ILE C  84   O  TYR C 145           
SHEET    7   P10 VAL C  58  ASN C  70 -1  N  ASN C  70   O  THR C  75           
SHEET    8   P10 SER C 202  ARG C 209  1  O  SER C 202   N  TYR C  63           
SHEET    9   P10 LEU C 231  PHE C 236 -1  O  ASP C 234   N  ILE C 207           
SHEET   10   P10 LEU C 221  ALA C 228 -1  N  VAL C 222   O  HIS C 235           
SHEET    1   Q 2 GLY C 161  ARG C 168  0                                        
SHEET    2   Q 2 LEU C 174  GLN C 181 -1  O  LEU C 177   N  SER C 165           
SHEET    1   R 2 LEU C 214  SER C 217  0                                        
SHEET    2   R 2 PHE C 249  SER C 252 -1  O  SER C 252   N  LEU C 214           
SHEET    1   S 5 GLU C 255  ILE C 260  0                                        
SHEET    2   S 5 LYS C 266  ALA C 271 -1  O  VAL C 267   N  LYS C 259           
SHEET    3   S 5 LYS C 305  ILE C 311  1  O  LEU C 308   N  SER C 268           
SHEET    4   S 5 LEU C 324  ARG C 328  1  O  TYR C 327   N  ALA C 309           
SHEET    5   S 5 ALA C 318  MET C 319 -1  N  MET C 319   O  THR C 326           
SHEET    1   T 2 THR C 365  MET C 366  0                                        
SHEET    2   T 2 ASN C 472  THR C 473  1  O  THR C 473   N  THR C 365           
SHEET    1   U 4 THR C 586  ILE C 590  0                                        
SHEET    2   U 4 ASN C 541  HIS C 548 -1  N  VAL C 542   O  LEU C 589           
SHEET    3   U 4 PRO C 531  ARG C 538 -1  N  LEU C 532   O  GLU C 547           
SHEET    4   U 4 ILE C 609  TYR C 612  1  O  HIS C 611   N  ILE C 533           
SHEET    1   V 3 HIS C 578  LEU C 582  0                                        
SHEET    2   V 3 VAL C 565  THR C 571 -1  N  VAL C 565   O  LEU C 582           
SHEET    3   V 3 ILE C 598  PHE C 600 -1  O  LYS C 599   N  ILE C 570           
SSBOND   1 CYS A  404    CYS A  443                          1555   1555  2.05  
SSBOND   2 CYS A  736    CYS A  743                          1555   1555  2.06  
SSBOND   3 CYS B  404    CYS B  443                          1555   1555  2.04  
SSBOND   4 CYS C  404    CYS C  443                          1555   1555  2.02  
LINK         ND2 ASN A  70                 C1  NAG A1001     1555   1555  1.43  
LINK         O6  MAN A1004                 C1  MAN A1005     1555   1555  1.44  
LINK         O4  NAG A1002                 C1  MAN A1004     1555   1555  1.44  
LINK         ND2 ASN B  70                 C1  NAG B1070     1555   1555  1.45  
LINK         O4  NAG A1001                 C1  NAG A1002     1555   1555  1.45  
LINK         ND2 ASN B 154                 C1  NAG B1154     1555   1555  1.45  
LINK         ND2 ASN C 154                 C1  NAG C1154     1555   1555  1.45  
LINK         ND2 ASN C  70                 C1  NAG C1070     1555   1555  1.46  
LINK         OE2 GLU B 376                ZN    ZN B5000     1555   1555  1.97  
LINK         OE2 GLU C 376                ZN    ZN C5000     1555   1555  1.98  
LINK         OE2 GLU A 376                ZN    ZN A5000     1555   1555  1.99  
LINK         NE2 HIS A 353                ZN    ZN A5000     1555   1555  2.07  
LINK         NE2 HIS A 357                ZN    ZN A5000     1555   1555  2.07  
LINK         NE2 HIS B 353                ZN    ZN B5000     1555   1555  2.07  
LINK         NE2 HIS C 353                ZN    ZN C5000     1555   1555  2.08  
LINK         NE2 HIS C 357                ZN    ZN C5000     1555   1555  2.08  
LINK         NE2 HIS B 357                ZN    ZN B5000     1555   1555  2.09  
LINK         OE1 GLU C 376                ZN    ZN C5000     1555   1555  2.23  
LINK         OE1 GLU A 376                ZN    ZN A5000     1555   1555  2.29  
LINK         OE1 GLU B 376                ZN    ZN B5000     1555   1555  2.35  
CISPEP   1 GLU A  183    PRO A  184          0         1.01                     
CISPEP   2 GLU B  183    PRO B  184          0        -0.79                     
CISPEP   3 ALA B  872    HIS B  873          0        -2.04                     
CISPEP   4 GLU C  183    PRO C  184          0         0.84                     
SITE     1 AC1  4 GLU A 320  HIS A 353  HIS A 357  GLU A 376                    
SITE     1 AC2  5 HIS A  68  ASN A  70  GLU A 210  LEU A 231                    
SITE     2 AC2  5 NAG A1002                                                     
SITE     1 AC3  4 GLU A 229  GLY A 230  NAG A1001  MAN A1004                    
SITE     1 AC4  4 GLU A 229  NAG A1002  MAN A1005  ALA C 111                    
SITE     1 AC5  7 MAN A1004  HIS B 611  GLU B 613  GLY B 650                    
SITE     2 AC5  7 LYS B 651  LEU B 652  ALA C 111                               
SITE     1 AC6  3 HIS B 353  HIS B 357  GLU B 376                               
SITE     1 AC7  1 ASN B 154                                                     
SITE     1 AC8  4 HIS B  68  ASN B  70  GLU B 210  LEU B 231                    
SITE     1 AC9  4 GLU C 320  HIS C 353  HIS C 357  GLU C 376                    
SITE     1 BC1  4 HIS C  68  ASN C  70  GLU C 210  LEU C 231                    
SITE     1 BC2  1 ASN C 154                                                     
CRYST1   97.246  132.816  233.687  90.00  90.00  90.00 P 21 21 21   12          
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      0.010283  0.000000  0.000000        0.00000                         
SCALE2      0.000000  0.007529  0.000000        0.00000                         
SCALE3      0.000000  0.000000  0.004279        0.00000                         
(ATOM LINES ARE NOT SHOWN.)
END                                                                             
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