HEADER TRANSPORT PROTEIN 20-MAY-13 4BOG
TITLE THE STRUCTURE AND SUPER-ORGANIZATION OF ACETYLCHOLINE RECEPTOR-RAPSYN
TITLE 2 COMPLEXES
COMPND MOL_ID: 1;
COMPND 2 MOLECULE: ACETYLCHOLINE RECEPTOR BETA SUBUNIT;
COMPND 3 CHAIN: 0, B, G, L, Q, V;
COMPND 4 MOL_ID: 2;
COMPND 5 MOLECULE: ACETYLCHOLINE RECEPTOR DELTA SUBUNIT;
COMPND 6 CHAIN: 1, C, H, M, R, W;
COMPND 7 MOL_ID: 3;
COMPND 8 MOLECULE: ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA;
COMPND 9 CHAIN: 2, A, D, F, I, K, N, P, S, U, X, Z;
COMPND 10 MOL_ID: 4;
COMPND 11 MOLECULE: ACETYLCHOLINE RECEPTOR GAMMA SUBUNIT;
COMPND 12 CHAIN: 3, E, J, O, T, Y
SOURCE MOL_ID: 1;
SOURCE 2 ORGANISM_SCIENTIFIC: TORPEDO MARMORATA;
SOURCE 3 ORGANISM_COMMON: MARBLED ELECTRIC RAY;
SOURCE 4 ORGANISM_TAXID: 7788;
SOURCE 5 CELL: ELECTROCYTE;
SOURCE 6 CELLULAR_LOCATION: POSTSYNAPTIC PLASMA MEMBRANE;
SOURCE 7 MOL_ID: 2;
SOURCE 8 ORGANISM_SCIENTIFIC: TORPEDO MARMORATA;
SOURCE 9 ORGANISM_COMMON: MARBLED ELECTRIC RAY;
SOURCE 10 ORGANISM_TAXID: 7788;
SOURCE 11 CELL: ELECTROCYTE;
SOURCE 12 CELLULAR_LOCATION: POSTSYNAPTIC PLASMA MEMBRANE;
SOURCE 13 MOL_ID: 3;
SOURCE 14 ORGANISM_SCIENTIFIC: TORPEDO MARMORATA;
SOURCE 15 ORGANISM_COMMON: MARBLED ELECTRIC RAY;
SOURCE 16 ORGANISM_TAXID: 7788;
SOURCE 17 CELL: ELECTROCYTE;
SOURCE 18 CELLULAR_LOCATION: POSTSYNAPTIC PLASMA MEMBRANE;
SOURCE 19 MOL_ID: 4;
SOURCE 20 ORGANISM_SCIENTIFIC: TORPEDO MARMORATA;
SOURCE 21 ORGANISM_COMMON: MARBLED ELECTRIC RAY;
SOURCE 22 ORGANISM_TAXID: 7788;
SOURCE 23 CELL: ELECTROCYTE;
SOURCE 24 CELLULAR_LOCATION: POSTSYNAPTIC PLASMA MEMBRANE
KEYWDS TRANSPORT PROTEIN, CLUSTERING, SYNAPSE, NEUROMUSCULAR JUNCTION,
KEYWDS 2 NICOTINIC, RAPSYN, 43K, ELECTRIC ORGAN
EXPDTA ELECTRON MICROSCOPY
AUTHOR B.ZUBER,N.UNWIN
REVDAT 5 23-OCT-19 4BOG 1 CRYST1 SCALE
REVDAT 4 11-SEP-19 4BOG 1 COMPND SOURCE REMARK DBREF
REVDAT 4 2 1 CRYST1
REVDAT 3 02-AUG-17 4BOG 1
REVDAT 2 10-JUL-13 4BOG 1 JRNL
REVDAT 1 26-JUN-13 4BOG 0
JRNL AUTH B.ZUBER,N.UNWIN
JRNL TITL STRUCTURE AND SUPERORGANIZATION OF ACETYLCHOLINE
JRNL TITL 2 RECEPTOR-RAPSYN COMPLEXES.
JRNL REF PROC.NATL.ACAD.SCI.USA V. 110 10622 2013
JRNL REFN ISSN 0027-8424
JRNL PMID 23754381
JRNL DOI 10.1073/PNAS.1301277110
REMARK 2
REMARK 2 RESOLUTION. 50.00 ANGSTROMS.
REMARK 3
REMARK 3 REFINEMENT.
REMARK 3 SOFTWARE PACKAGES : UCSF CHIMERA, IMOD, PRIISM/IVE, TOMO3D,
REMARK 3 XMIPP
REMARK 3 RECONSTRUCTION SCHEMA : NULL
REMARK 3
REMARK 3 EM MAP-MODEL FITTING AND REFINEMENT
REMARK 3 PDB ENTRY : 2BG9
REMARK 3 REFINEMENT SPACE : REAL
REMARK 3 REFINEMENT PROTOCOL : OTHER
REMARK 3 REFINEMENT TARGET : NULL
REMARK 3 OVERALL ANISOTROPIC B VALUE : NULL
REMARK 3
REMARK 3 FITTING PROCEDURE : METHOD--LOCAL CORRELATION REFINEMENT PROTOCOL-
REMARK 3 -ELECTRON MICROSCOPY
REMARK 3
REMARK 3 EM IMAGE RECONSTRUCTION STATISTICS
REMARK 3 NOMINAL PIXEL SIZE (ANGSTROMS) : 7.480
REMARK 3 ACTUAL PIXEL SIZE (ANGSTROMS) : NULL
REMARK 3 EFFECTIVE RESOLUTION (ANGSTROMS) : 50.00
REMARK 3 NUMBER OF PARTICLES : 3564
REMARK 3 CTF CORRECTION METHOD : NULL
REMARK 3
REMARK 3 EM RECONSTRUCTION MAGNIFICATION CALIBRATION: CATALASE CRYSTAL
REMARK 3
REMARK 3 OTHER DETAILS: SUBMISSION BASED ON EXPERIMENTAL DATA FROM EMDB EMD
REMARK 3 -2376. (DEPOSITION ID: 11658).
REMARK 4
REMARK 4 4BOG COMPLIES WITH FORMAT V. 3.30, 13-JUL-11
REMARK 100
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBE.
REMARK 100 THE DEPOSITION ID IS D_1290056908.
REMARK 245
REMARK 245 EXPERIMENTAL DETAILS
REMARK 245 RECONSTRUCTION METHOD : TOMOGRAPHY
REMARK 245 SPECIMEN TYPE : VITREOUS ICE
REMARK 245
REMARK 245 ELECTRON MICROSCOPE SAMPLE
REMARK 245 SAMPLE TYPE : PARTICLE
REMARK 245 PARTICLE TYPE : POINT
REMARK 245 NAME OF SAMPLE : ACETYLCHOLINE RECEPTOR- RAPSYN
REMARK 245 COMPLEX
REMARK 245 SAMPLE CONCENTRATION (MG ML-1) : NULL
REMARK 245 SAMPLE SUPPORT DETAILS : HOLEY CARBON
REMARK 245 SAMPLE VITRIFICATION DETAILS : ETHANE
REMARK 245 SAMPLE BUFFER : 400 MM NACL, 20 MM PHOSPHATE
REMARK 245 BUFFER, LEUPEPTIN 0.3 MG/L,
REMARK 245 PEPSTATIN 1 MG/L
REMARK 245 PH : 7.40
REMARK 245 SAMPLE DETAILS : NULL
REMARK 245
REMARK 245 DATA ACQUISITION
REMARK 245 DATE OF EXPERIMENT : 25-JUL-08
REMARK 245 NUMBER OF MICROGRAPHS-IMAGES : NULL
REMARK 245 TEMPERATURE (KELVIN) : 85.00
REMARK 245 MICROSCOPE MODEL : FEI TECNAI F30
REMARK 245 DETECTOR TYPE : GATAN ULTRASCAN 4000 (4K X
REMARK 245 4K)
REMARK 245 MINIMUM DEFOCUS (NM) : 3000.00
REMARK 245 MAXIMUM DEFOCUS (NM) : 6000.00
REMARK 245 MINIMUM TILT ANGLE (DEGREES) : -70.00
REMARK 245 MAXIMUM TILT ANGLE (DEGREES) : 70.00
REMARK 245 NOMINAL CS : 2.00
REMARK 245 IMAGING MODE : BRIGHT FIELD
REMARK 245 ELECTRON DOSE (ELECTRONS NM**-2) : 50.00
REMARK 245 ILLUMINATION MODE : FLOOD BEAM
REMARK 245 NOMINAL MAGNIFICATION : 69000
REMARK 245 CALIBRATED MAGNIFICATION : 80213
REMARK 245 SOURCE : FIELD EMISSION GUN
REMARK 245 ACCELERATION VOLTAGE (KV) : 300
REMARK 245 IMAGING DETAILS : NULL
REMARK 247
REMARK 247 ELECTRON MICROSCOPY
REMARK 247 THE COORDINATES IN THIS ENTRY WERE GENERATED FROM ELECTRON
REMARK 247 MICROSCOPY DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE
REMARK 247 THAT CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES
REMARK 247 ON THESE RECORDS ARE MEANINGLESS EXCEPT FOR THE CALCULATION
REMARK 247 OF THE STRUCTURE FACTORS.
REMARK 300
REMARK 300 BIOMOLECULE: 1
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON
REMARK 300 BURIED SURFACE AREA.
REMARK 350
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS
REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.
REMARK 350
REMARK 350 BIOMOLECULE: 1
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: 30-MERIC
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: 30-MERIC
REMARK 350 SOFTWARE USED: PISA
REMARK 350 APPLY THE FOLLOWING TO CHAINS: 0, 1, 2, 3, A, B, C, D, E, F,
REMARK 350 AND CHAINS: G, H, I, J, K, L, M, N, O,
REMARK 350 AND CHAINS: P, Q, R, S, T, U, V, W, X, Y,
REMARK 350 AND CHAINS: Z
REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000
REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000
REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000
REMARK 465
REMARK 465 MISSING RESIDUES
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)
REMARK 465
REMARK 465 M RES C SSSEQI
REMARK 465 MET 0 -23
REMARK 465 GLU 0 -22
REMARK 465 ASP 0 -21
REMARK 465 VAL 0 -20
REMARK 465 ARG 0 -19
REMARK 465 ARG 0 -18
REMARK 465 MET 0 -17
REMARK 465 ALA 0 -16
REMARK 465 LEU 0 -15
REMARK 465 GLY 0 -14
REMARK 465 LEU 0 -13
REMARK 465 VAL 0 -12
REMARK 465 VAL 0 -11
REMARK 465 MET 0 -10
REMARK 465 MET 0 -9
REMARK 465 ALA 0 -8
REMARK 465 LEU 0 -7
REMARK 465 ALA 0 -6
REMARK 465 LEU 0 -5
REMARK 465 SER 0 -4
REMARK 465 GLY 0 -3
REMARK 465 VAL 0 -2
REMARK 465 GLY 0 -1
REMARK 465 ALA 0 0
REMARK 465 LYS 0 165
REMARK 465 GLY 0 166
REMARK 465 GLU 0 167
REMARK 465 ARG 0 168
REMARK 465 GLU 0 169
REMARK 465 VAL 0 170
REMARK 465 LYS 0 171
REMARK 465 GLU 0 172
REMARK 465 ILE 0 173
REMARK 465 THR 0 313
REMARK 465 MET 0 314
REMARK 465 PRO 0 315
REMARK 465 ASN 0 316
REMARK 465 TRP 0 317
REMARK 465 ILE 0 318
REMARK 465 ARG 0 319
REMARK 465 GLN 0 320
REMARK 465 ILE 0 321
REMARK 465 PHE 0 322
REMARK 465 ILE 0 323
REMARK 465 GLU 0 324
REMARK 465 THR 0 325
REMARK 465 LEU 0 326
REMARK 465 PRO 0 327
REMARK 465 PRO 0 328
REMARK 465 PHE 0 329
REMARK 465 LEU 0 330
REMARK 465 TRP 0 331
REMARK 465 ILE 0 332
REMARK 465 GLN 0 333
REMARK 465 ARG 0 334
REMARK 465 PRO 0 335
REMARK 465 VAL 0 336
REMARK 465 THR 0 337
REMARK 465 THR 0 338
REMARK 465 PRO 0 339
REMARK 465 SER 0 340
REMARK 465 PRO 0 341
REMARK 465 ASP 0 342
REMARK 465 SER 0 343
REMARK 465 LYS 0 344
REMARK 465 PRO 0 345
REMARK 465 THR 0 346
REMARK 465 ILE 0 347
REMARK 465 ILE 0 348
REMARK 465 SER 0 349
REMARK 465 ARG 0 350
REMARK 465 ALA 0 351
REMARK 465 ASN 0 352
REMARK 465 ASP 0 353
REMARK 465 GLU 0 354
REMARK 465 TYR 0 355
REMARK 465 PHE 0 356
REMARK 465 ILE 0 357
REMARK 465 ARG 0 358
REMARK 465 LYS 0 359
REMARK 465 PRO 0 360
REMARK 465 ALA 0 361
REMARK 465 GLY 0 362
REMARK 465 ASP 0 363
REMARK 465 PHE 0 364
REMARK 465 VAL 0 365
REMARK 465 CYS 0 366
REMARK 465 PRO 0 367
REMARK 465 VAL 0 368
REMARK 465 ASP 0 369
REMARK 465 ASN 0 370
REMARK 465 ALA 0 371
REMARK 465 ARG 0 372
REMARK 465 VAL 0 373
REMARK 465 ALA 0 374
REMARK 465 VAL 0 375
REMARK 465 GLN 0 376
REMARK 465 PRO 0 377
REMARK 465 GLU 0 378
REMARK 465 ARG 0 379
REMARK 465 LEU 0 380
REMARK 465 PHE 0 381
REMARK 465 SER 0 382
REMARK 465 GLU 0 383
REMARK 465 MET 0 384
REMARK 465 LYS 0 385
REMARK 465 TRP 0 386
REMARK 465 HIS 0 387
REMARK 465 LEU 0 388
REMARK 465 ASN 0 389
REMARK 465 GLY 0 390
REMARK 465 LEU 0 391
REMARK 465 THR 0 392
REMARK 465 GLN 0 393
REMARK 465 PRO 0 394
REMARK 465 VAL 0 395
REMARK 465 THR 0 396
REMARK 465 LEU 0 397
REMARK 465 PRO 0 398
REMARK 465 GLN 0 399
REMARK 465 ASP 0 400
REMARK 465 LEU 0 401
REMARK 465 LYS 0 402
REMARK 465 MET 1 -20
REMARK 465 GLY 1 -19
REMARK 465 ASN 1 -18
REMARK 465 ILE 1 -17
REMARK 465 HIS 1 -16
REMARK 465 PHE 1 -15
REMARK 465 VAL 1 -14
REMARK 465 TYR 1 -13
REMARK 465 LEU 1 -12
REMARK 465 LEU 1 -11
REMARK 465 ILE 1 -10
REMARK 465 SER 1 -9
REMARK 465 CYS 1 -8
REMARK 465 LEU 1 -7
REMARK 465 TYR 1 -6
REMARK 465 TYR 1 -5
REMARK 465 SER 1 -4
REMARK 465 GLY 1 -3
REMARK 465 CYS 1 -2
REMARK 465 SER 1 -1
REMARK 465 GLY 1 0
REMARK 465 MET 1 163
REMARK 465 THR 1 164
REMARK 465 ASP 1 165
REMARK 465 THR 1 166
REMARK 465 ILE 1 167
REMARK 465 ASP 1 168
REMARK 465 GLY 1 169
REMARK 465 LYS 1 170
REMARK 465 ASP 1 171
REMARK 465 TYR 1 172
REMARK 465 PRO 1 173
REMARK 465 ILE 1 174
REMARK 465 GLU 1 175
REMARK 465 TRP 1 176
REMARK 465 ILE 1 177
REMARK 465 VAL 1 321
REMARK 465 LEU 1 322
REMARK 465 SER 1 323
REMARK 465 THR 1 324
REMARK 465 ARG 1 325
REMARK 465 VAL 1 326
REMARK 465 LYS 1 327
REMARK 465 GLN 1 328
REMARK 465 ILE 1 329
REMARK 465 PHE 1 330
REMARK 465 LEU 1 331
REMARK 465 GLU 1 332
REMARK 465 LYS 1 333
REMARK 465 LEU 1 334
REMARK 465 PRO 1 335
REMARK 465 ARG 1 336
REMARK 465 ILE 1 337
REMARK 465 LEU 1 338
REMARK 465 HIS 1 339
REMARK 465 MET 1 340
REMARK 465 SER 1 341
REMARK 465 ARG 1 342
REMARK 465 VAL 1 343
REMARK 465 ASP 1 344
REMARK 465 GLU 1 345
REMARK 465 ILE 1 346
REMARK 465 GLU 1 347
REMARK 465 GLN 1 348
REMARK 465 PRO 1 349
REMARK 465 ASP 1 350
REMARK 465 TRP 1 351
REMARK 465 GLN 1 352
REMARK 465 ASN 1 353
REMARK 465 ASP 1 354
REMARK 465 LEU 1 355
REMARK 465 LYS 1 356
REMARK 465 LEU 1 357
REMARK 465 ARG 1 358
REMARK 465 ARG 1 359
REMARK 465 SER 1 360
REMARK 465 SER 1 361
REMARK 465 SER 1 362
REMARK 465 VAL 1 363
REMARK 465 GLY 1 364
REMARK 465 TYR 1 365
REMARK 465 ILE 1 366
REMARK 465 SER 1 367
REMARK 465 LYS 1 368
REMARK 465 ALA 1 369
REMARK 465 GLN 1 370
REMARK 465 GLU 1 371
REMARK 465 TYR 1 372
REMARK 465 PHE 1 373
REMARK 465 ASN 1 374
REMARK 465 ILE 1 375
REMARK 465 LYS 1 376
REMARK 465 SER 1 377
REMARK 465 ARG 1 378
REMARK 465 SER 1 379
REMARK 465 GLU 1 380
REMARK 465 LEU 1 381
REMARK 465 MET 1 382
REMARK 465 PHE 1 383
REMARK 465 GLU 1 384
REMARK 465 LYS 1 385
REMARK 465 GLN 1 386
REMARK 465 SER 1 387
REMARK 465 GLU 1 388
REMARK 465 ARG 1 389
REMARK 465 HIS 1 390
REMARK 465 GLY 1 391
REMARK 465 LEU 1 392
REMARK 465 VAL 1 393
REMARK 465 PRO 1 394
REMARK 465 ARG 1 395
REMARK 465 VAL 1 396
REMARK 465 THR 1 397
REMARK 465 PRO 1 398
REMARK 465 ARG 1 399
REMARK 465 ILE 1 400
REMARK 465 GLY 1 401
REMARK 465 PHE 1 402
REMARK 465 GLY 1 403
REMARK 465 ASN 1 404
REMARK 465 ASN 1 405
REMARK 465 ASN 1 406
REMARK 465 GLU 1 407
REMARK 465 ASN 1 408
REMARK 465 ILE 1 409
REMARK 465 ALA 1 410
REMARK 465 ALA 1 411
REMARK 465 SER 1 412
REMARK 465 ASP 1 413
REMARK 465 GLN 1 414
REMARK 465 LEU 1 415
REMARK 465 HIS 1 416
REMARK 465 ASP 1 417
REMARK 465 GLU 1 418
REMARK 465 ILE 1 419
REMARK 465 LYS 1 420
REMARK 465 PHE 1 486
REMARK 465 GLU 1 487
REMARK 465 GLY 1 488
REMARK 465 ASP 1 489
REMARK 465 PRO 1 490
REMARK 465 PHE 1 491
REMARK 465 ASP 1 492
REMARK 465 TYR 1 493
REMARK 465 SER 1 494
REMARK 465 SER 1 495
REMARK 465 ASP 1 496
REMARK 465 HIS 1 497
REMARK 465 PRO 1 498
REMARK 465 ARG 1 499
REMARK 465 CYS 1 500
REMARK 465 ALA 1 501
REMARK 465 MET 2 -23
REMARK 465 ILE 2 -22
REMARK 465 LEU 2 -21
REMARK 465 CYS 2 -20
REMARK 465 SER 2 -19
REMARK 465 TYR 2 -18
REMARK 465 TRP 2 -17
REMARK 465 HIS 2 -16
REMARK 465 VAL 2 -15
REMARK 465 GLY 2 -14
REMARK 465 LEU 2 -13
REMARK 465 VAL 2 -12
REMARK 465 LEU 2 -11
REMARK 465 LEU 2 -10
REMARK 465 LEU 2 -9
REMARK 465 PHE 2 -8
REMARK 465 SER 2 -7
REMARK 465 CYS 2 -6
REMARK 465 CYS 2 -5
REMARK 465 GLY 2 -4
REMARK 465 LEU 2 -3
REMARK 465 VAL 2 -2
REMARK 465 LEU 2 -1
REMARK 465 GLY 2 0
REMARK 465 THR 2 307
REMARK 465 MET 2 308
REMARK 465 PRO 2 309
REMARK 465 GLN 2 310
REMARK 465 TRP 2 311
REMARK 465 VAL 2 312
REMARK 465 ARG 2 313
REMARK 465 LYS 2 314
REMARK 465 ILE 2 315
REMARK 465 PHE 2 316
REMARK 465 ILE 2 317
REMARK 465 ASN 2 318
REMARK 465 THR 2 319
REMARK 465 ILE 2 320
REMARK 465 PRO 2 321
REMARK 465 ASN 2 322
REMARK 465 VAL 2 323
REMARK 465 MET 2 324
REMARK 465 PHE 2 325
REMARK 465 PHE 2 326
REMARK 465 SER 2 327
REMARK 465 THR 2 328
REMARK 465 MET 2 329
REMARK 465 LYS 2 330
REMARK 465 ARG 2 331
REMARK 465 ALA 2 332
REMARK 465 SER 2 333
REMARK 465 LYS 2 334
REMARK 465 GLU 2 335
REMARK 465 LYS 2 336
REMARK 465 GLN 2 337
REMARK 465 GLU 2 338
REMARK 465 ASN 2 339
REMARK 465 LYS 2 340
REMARK 465 ILE 2 341
REMARK 465 PHE 2 342
REMARK 465 ALA 2 343
REMARK 465 ASP 2 344
REMARK 465 ASP 2 345
REMARK 465 ILE 2 346
REMARK 465 ASP 2 347
REMARK 465 ILE 2 348
REMARK 465 SER 2 349
REMARK 465 ASP 2 350
REMARK 465 ILE 2 351
REMARK 465 SER 2 352
REMARK 465 GLY 2 353
REMARK 465 LYS 2 354
REMARK 465 GLN 2 355
REMARK 465 VAL 2 356
REMARK 465 THR 2 357
REMARK 465 GLY 2 358
REMARK 465 GLU 2 359
REMARK 465 VAL 2 360
REMARK 465 ILE 2 361
REMARK 465 PHE 2 362
REMARK 465 GLN 2 363
REMARK 465 THR 2 364
REMARK 465 PRO 2 365
REMARK 465 LEU 2 366
REMARK 465 ILE 2 367
REMARK 465 LYS 2 368
REMARK 465 ASN 2 369
REMARK 465 PRO 2 370
REMARK 465 ASP 2 371
REMARK 465 VAL 2 372
REMARK 465 LYS 2 373
REMARK 465 MET 3 -16
REMARK 465 VAL 3 -15
REMARK 465 LEU 3 -14
REMARK 465 THR 3 -13
REMARK 465 LEU 3 -12
REMARK 465 LEU 3 -11
REMARK 465 LEU 3 -10
REMARK 465 ILE 3 -9
REMARK 465 ILE 3 -8
REMARK 465 CYS 3 -7
REMARK 465 LEU 3 -6
REMARK 465 ALA 3 -5
REMARK 465 LEU 3 -4
REMARK 465 GLU 3 -3
REMARK 465 VAL 3 -2
REMARK 465 ARG 3 -1
REMARK 465 SER 3 0
REMARK 465 GLU 3 165
REMARK 465 VAL 3 166
REMARK 465 VAL 3 167
REMARK 465 GLU 3 168
REMARK 465 TRP 3 169
REMARK 465 ILE 3 170
REMARK 465 HIS 3 171
REMARK 465 SER 3 315
REMARK 465 LEU 3 316
REMARK 465 SER 3 317
REMARK 465 GLU 3 318
REMARK 465 LYS 3 319
REMARK 465 ILE 3 320
REMARK 465 LYS 3 321
REMARK 465 HIS 3 322
REMARK 465 LEU 3 323
REMARK 465 PHE 3 324
REMARK 465 LEU 3 325
REMARK 465 GLU 3 326
REMARK 465 PHE 3 327
REMARK 465 LEU 3 328
REMARK 465 PRO 3 329
REMARK 465 LYS 3 330
REMARK 465 TYR 3 331
REMARK 465 LEU 3 332
REMARK 465 GLY 3 333
REMARK 465 MET 3 334
REMARK 465 HIS 3 335
REMARK 465 LEU 3 336
REMARK 465 GLU 3 337
REMARK 465 PRO 3 338
REMARK 465 SER 3 339
REMARK 465 GLU 3 340
REMARK 465 GLU 3 341
REMARK 465 THR 3 342
REMARK 465 PRO 3 343
REMARK 465 GLU 3 344
REMARK 465 LYS 3 345
REMARK 465 PRO 3 346
REMARK 465 GLN 3 347
REMARK 465 PRO 3 348
REMARK 465 ARG 3 349
REMARK 465 ARG 3 350
REMARK 465 ARG 3 351
REMARK 465 SER 3 352
REMARK 465 SER 3 353
REMARK 465 PHE 3 354
REMARK 465 GLY 3 355
REMARK 465 ILE 3 356
REMARK 465 MET 3 357
REMARK 465 ILE 3 358
REMARK 465 LYS 3 359
REMARK 465 ALA 3 360
REMARK 465 GLU 3 361
REMARK 465 GLU 3 362
REMARK 465 TYR 3 363
REMARK 465 ILE 3 364
REMARK 465 LEU 3 365
REMARK 465 LYS 3 366
REMARK 465 LYS 3 367
REMARK 465 PRO 3 368
REMARK 465 ARG 3 369
REMARK 465 SER 3 370
REMARK 465 GLU 3 371
REMARK 465 LEU 3 372
REMARK 465 MET 3 373
REMARK 465 PHE 3 374
REMARK 465 GLU 3 375
REMARK 465 GLU 3 376
REMARK 465 GLN 3 377
REMARK 465 LYS 3 378
REMARK 465 ASP 3 379
REMARK 465 ARG 3 380
REMARK 465 HIS 3 381
REMARK 465 GLY 3 382
REMARK 465 LEU 3 383
REMARK 465 LYS 3 384
REMARK 465 ARG 3 385
REMARK 465 VAL 3 386
REMARK 465 ASN 3 387
REMARK 465 LYS 3 388
REMARK 465 MET 3 389
REMARK 465 THR 3 390
REMARK 465 SER 3 391
REMARK 465 ASP 3 392
REMARK 465 ILE 3 393
REMARK 465 ASP 3 394
REMARK 465 ILE 3 395
REMARK 465 GLY 3 396
REMARK 465 THR 3 397
REMARK 465 THR 3 398
REMARK 465 VAL 3 399
REMARK 465 ASP 3 400
REMARK 465 LEU 3 401
REMARK 465 TYR 3 402
REMARK 465 LYS 3 403
REMARK 465 ASP 3 404
REMARK 465 LEU 3 405
REMARK 465 ALA 3 406
REMARK 465 ASN 3 407
REMARK 465 PHE 3 408
REMARK 465 ALA 3 409
REMARK 465 PRO 3 410
REMARK 465 GLU 3 411
REMARK 465 ILE 3 412
REMARK 465 LYS 3 413
REMARK 465 PRO 3 478
REMARK 465 PHE 3 479
REMARK 465 PRO 3 480
REMARK 465 GLY 3 481
REMARK 465 ASP 3 482
REMARK 465 PRO 3 483
REMARK 465 ARG 3 484
REMARK 465 LYS 3 485
REMARK 465 TYR 3 486
REMARK 465 VAL 3 487
REMARK 465 PRO 3 488
REMARK 465 MET A -23
REMARK 465 ILE A -22
REMARK 465 LEU A -21
REMARK 465 CYS A -20
REMARK 465 SER A -19
REMARK 465 TYR A -18
REMARK 465 TRP A -17
REMARK 465 HIS A -16
REMARK 465 VAL A -15
REMARK 465 GLY A -14
REMARK 465 LEU A -13
REMARK 465 VAL A -12
REMARK 465 LEU A -11
REMARK 465 LEU A -10
REMARK 465 LEU A -9
REMARK 465 PHE A -8
REMARK 465 SER A -7
REMARK 465 CYS A -6
REMARK 465 CYS A -5
REMARK 465 GLY A -4
REMARK 465 LEU A -3
REMARK 465 VAL A -2
REMARK 465 LEU A -1
REMARK 465 GLY A 0
REMARK 465 THR A 307
REMARK 465 MET A 308
REMARK 465 PRO A 309
REMARK 465 GLN A 310
REMARK 465 TRP A 311
REMARK 465 VAL A 312
REMARK 465 ARG A 313
REMARK 465 LYS A 314
REMARK 465 ILE A 315
REMARK 465 PHE A 316
REMARK 465 ILE A 317
REMARK 465 ASN A 318
REMARK 465 THR A 319
REMARK 465 ILE A 320
REMARK 465 PRO A 321
REMARK 465 ASN A 322
REMARK 465 VAL A 323
REMARK 465 MET A 324
REMARK 465 PHE A 325
REMARK 465 PHE A 326
REMARK 465 SER A 327
REMARK 465 THR A 328
REMARK 465 MET A 329
REMARK 465 LYS A 330
REMARK 465 ARG A 331
REMARK 465 ALA A 332
REMARK 465 SER A 333
REMARK 465 LYS A 334
REMARK 465 GLU A 335
REMARK 465 LYS A 336
REMARK 465 GLN A 337
REMARK 465 GLU A 338
REMARK 465 ASN A 339
REMARK 465 LYS A 340
REMARK 465 ILE A 341
REMARK 465 PHE A 342
REMARK 465 ALA A 343
REMARK 465 ASP A 344
REMARK 465 ASP A 345
REMARK 465 ILE A 346
REMARK 465 ASP A 347
REMARK 465 ILE A 348
REMARK 465 SER A 349
REMARK 465 ASP A 350
REMARK 465 ILE A 351
REMARK 465 SER A 352
REMARK 465 GLY A 353
REMARK 465 LYS A 354
REMARK 465 GLN A 355
REMARK 465 VAL A 356
REMARK 465 THR A 357
REMARK 465 GLY A 358
REMARK 465 GLU A 359
REMARK 465 VAL A 360
REMARK 465 ILE A 361
REMARK 465 PHE A 362
REMARK 465 GLN A 363
REMARK 465 THR A 364
REMARK 465 PRO A 365
REMARK 465 LEU A 366
REMARK 465 ILE A 367
REMARK 465 LYS A 368
REMARK 465 ASN A 369
REMARK 465 PRO A 370
REMARK 465 ASP A 371
REMARK 465 VAL A 372
REMARK 465 LYS A 373
REMARK 465 MET B -23
REMARK 465 GLU B -22
REMARK 465 ASP B -21
REMARK 465 VAL B -20
REMARK 465 ARG B -19
REMARK 465 ARG B -18
REMARK 465 MET B -17
REMARK 465 ALA B -16
REMARK 465 LEU B -15
REMARK 465 GLY B -14
REMARK 465 LEU B -13
REMARK 465 VAL B -12
REMARK 465 VAL B -11
REMARK 465 MET B -10
REMARK 465 MET B -9
REMARK 465 ALA B -8
REMARK 465 LEU B -7
REMARK 465 ALA B -6
REMARK 465 LEU B -5
REMARK 465 SER B -4
REMARK 465 GLY B -3
REMARK 465 VAL B -2
REMARK 465 GLY B -1
REMARK 465 ALA B 0
REMARK 465 LYS B 165
REMARK 465 GLY B 166
REMARK 465 GLU B 167
REMARK 465 ARG B 168
REMARK 465 GLU B 169
REMARK 465 VAL B 170
REMARK 465 LYS B 171
REMARK 465 GLU B 172
REMARK 465 ILE B 173
REMARK 465 THR B 313
REMARK 465 MET B 314
REMARK 465 PRO B 315
REMARK 465 ASN B 316
REMARK 465 TRP B 317
REMARK 465 ILE B 318
REMARK 465 ARG B 319
REMARK 465 GLN B 320
REMARK 465 ILE B 321
REMARK 465 PHE B 322
REMARK 465 ILE B 323
REMARK 465 GLU B 324
REMARK 465 THR B 325
REMARK 465 LEU B 326
REMARK 465 PRO B 327
REMARK 465 PRO B 328
REMARK 465 PHE B 329
REMARK 465 LEU B 330
REMARK 465 TRP B 331
REMARK 465 ILE B 332
REMARK 465 GLN B 333
REMARK 465 ARG B 334
REMARK 465 PRO B 335
REMARK 465 VAL B 336
REMARK 465 THR B 337
REMARK 465 THR B 338
REMARK 465 PRO B 339
REMARK 465 SER B 340
REMARK 465 PRO B 341
REMARK 465 ASP B 342
REMARK 465 SER B 343
REMARK 465 LYS B 344
REMARK 465 PRO B 345
REMARK 465 THR B 346
REMARK 465 ILE B 347
REMARK 465 ILE B 348
REMARK 465 SER B 349
REMARK 465 ARG B 350
REMARK 465 ALA B 351
REMARK 465 ASN B 352
REMARK 465 ASP B 353
REMARK 465 GLU B 354
REMARK 465 TYR B 355
REMARK 465 PHE B 356
REMARK 465 ILE B 357
REMARK 465 ARG B 358
REMARK 465 LYS B 359
REMARK 465 PRO B 360
REMARK 465 ALA B 361
REMARK 465 GLY B 362
REMARK 465 ASP B 363
REMARK 465 PHE B 364
REMARK 465 VAL B 365
REMARK 465 CYS B 366
REMARK 465 PRO B 367
REMARK 465 VAL B 368
REMARK 465 ASP B 369
REMARK 465 ASN B 370
REMARK 465 ALA B 371
REMARK 465 ARG B 372
REMARK 465 VAL B 373
REMARK 465 ALA B 374
REMARK 465 VAL B 375
REMARK 465 GLN B 376
REMARK 465 PRO B 377
REMARK 465 GLU B 378
REMARK 465 ARG B 379
REMARK 465 LEU B 380
REMARK 465 PHE B 381
REMARK 465 SER B 382
REMARK 465 GLU B 383
REMARK 465 MET B 384
REMARK 465 LYS B 385
REMARK 465 TRP B 386
REMARK 465 HIS B 387
REMARK 465 LEU B 388
REMARK 465 ASN B 389
REMARK 465 GLY B 390
REMARK 465 LEU B 391
REMARK 465 THR B 392
REMARK 465 GLN B 393
REMARK 465 PRO B 394
REMARK 465 VAL B 395
REMARK 465 THR B 396
REMARK 465 LEU B 397
REMARK 465 PRO B 398
REMARK 465 GLN B 399
REMARK 465 ASP B 400
REMARK 465 LEU B 401
REMARK 465 LYS B 402
REMARK 465 MET C -20
REMARK 465 GLY C -19
REMARK 465 ASN C -18
REMARK 465 ILE C -17
REMARK 465 HIS C -16
REMARK 465 PHE C -15
REMARK 465 VAL C -14
REMARK 465 TYR C -13
REMARK 465 LEU C -12
REMARK 465 LEU C -11
REMARK 465 ILE C -10
REMARK 465 SER C -9
REMARK 465 CYS C -8
REMARK 465 LEU C -7
REMARK 465 TYR C -6
REMARK 465 TYR C -5
REMARK 465 SER C -4
REMARK 465 GLY C -3
REMARK 465 CYS C -2
REMARK 465 SER C -1
REMARK 465 GLY C 0
REMARK 465 MET C 163
REMARK 465 THR C 164
REMARK 465 ASP C 165
REMARK 465 THR C 166
REMARK 465 ILE C 167
REMARK 465 ASP C 168
REMARK 465 GLY C 169
REMARK 465 LYS C 170
REMARK 465 ASP C 171
REMARK 465 TYR C 172
REMARK 465 PRO C 173
REMARK 465 ILE C 174
REMARK 465 GLU C 175
REMARK 465 TRP C 176
REMARK 465 ILE C 177
REMARK 465 VAL C 321
REMARK 465 LEU C 322
REMARK 465 SER C 323
REMARK 465 THR C 324
REMARK 465 ARG C 325
REMARK 465 VAL C 326
REMARK 465 LYS C 327
REMARK 465 GLN C 328
REMARK 465 ILE C 329
REMARK 465 PHE C 330
REMARK 465 LEU C 331
REMARK 465 GLU C 332
REMARK 465 LYS C 333
REMARK 465 LEU C 334
REMARK 465 PRO C 335
REMARK 465 ARG C 336
REMARK 465 ILE C 337
REMARK 465 LEU C 338
REMARK 465 HIS C 339
REMARK 465 MET C 340
REMARK 465 SER C 341
REMARK 465 ARG C 342
REMARK 465 VAL C 343
REMARK 465 ASP C 344
REMARK 465 GLU C 345
REMARK 465 ILE C 346
REMARK 465 GLU C 347
REMARK 465 GLN C 348
REMARK 465 PRO C 349
REMARK 465 ASP C 350
REMARK 465 TRP C 351
REMARK 465 GLN C 352
REMARK 465 ASN C 353
REMARK 465 ASP C 354
REMARK 465 LEU C 355
REMARK 465 LYS C 356
REMARK 465 LEU C 357
REMARK 465 ARG C 358
REMARK 465 ARG C 359
REMARK 465 SER C 360
REMARK 465 SER C 361
REMARK 465 SER C 362
REMARK 465 VAL C 363
REMARK 465 GLY C 364
REMARK 465 TYR C 365
REMARK 465 ILE C 366
REMARK 465 SER C 367
REMARK 465 LYS C 368
REMARK 465 ALA C 369
REMARK 465 GLN C 370
REMARK 465 GLU C 371
REMARK 465 TYR C 372
REMARK 465 PHE C 373
REMARK 465 ASN C 374
REMARK 465 ILE C 375
REMARK 465 LYS C 376
REMARK 465 SER C 377
REMARK 465 ARG C 378
REMARK 465 SER C 379
REMARK 465 GLU C 380
REMARK 465 LEU C 381
REMARK 465 MET C 382
REMARK 465 PHE C 383
REMARK 465 GLU C 384
REMARK 465 LYS C 385
REMARK 465 GLN C 386
REMARK 465 SER C 387
REMARK 465 GLU C 388
REMARK 465 ARG C 389
REMARK 465 HIS C 390
REMARK 465 GLY C 391
REMARK 465 LEU C 392
REMARK 465 VAL C 393
REMARK 465 PRO C 394
REMARK 465 ARG C 395
REMARK 465 VAL C 396
REMARK 465 THR C 397
REMARK 465 PRO C 398
REMARK 465 ARG C 399
REMARK 465 ILE C 400
REMARK 465 GLY C 401
REMARK 465 PHE C 402
REMARK 465 GLY C 403
REMARK 465 ASN C 404
REMARK 465 ASN C 405
REMARK 465 ASN C 406
REMARK 465 GLU C 407
REMARK 465 ASN C 408
REMARK 465 ILE C 409
REMARK 465 ALA C 410
REMARK 465 ALA C 411
REMARK 465 SER C 412
REMARK 465 ASP C 413
REMARK 465 GLN C 414
REMARK 465 LEU C 415
REMARK 465 HIS C 416
REMARK 465 ASP C 417
REMARK 465 GLU C 418
REMARK 465 ILE C 419
REMARK 465 LYS C 420
REMARK 465 PHE C 486
REMARK 465 GLU C 487
REMARK 465 GLY C 488
REMARK 465 ASP C 489
REMARK 465 PRO C 490
REMARK 465 PHE C 491
REMARK 465 ASP C 492
REMARK 465 TYR C 493
REMARK 465 SER C 494
REMARK 465 SER C 495
REMARK 465 ASP C 496
REMARK 465 HIS C 497
REMARK 465 PRO C 498
REMARK 465 ARG C 499
REMARK 465 CYS C 500
REMARK 465 ALA C 501
REMARK 465 MET D -23
REMARK 465 ILE D -22
REMARK 465 LEU D -21
REMARK 465 CYS D -20
REMARK 465 SER D -19
REMARK 465 TYR D -18
REMARK 465 TRP D -17
REMARK 465 HIS D -16
REMARK 465 VAL D -15
REMARK 465 GLY D -14
REMARK 465 LEU D -13
REMARK 465 VAL D -12
REMARK 465 LEU D -11
REMARK 465 LEU D -10
REMARK 465 LEU D -9
REMARK 465 PHE D -8
REMARK 465 SER D -7
REMARK 465 CYS D -6
REMARK 465 CYS D -5
REMARK 465 GLY D -4
REMARK 465 LEU D -3
REMARK 465 VAL D -2
REMARK 465 LEU D -1
REMARK 465 GLY D 0
REMARK 465 THR D 307
REMARK 465 MET D 308
REMARK 465 PRO D 309
REMARK 465 GLN D 310
REMARK 465 TRP D 311
REMARK 465 VAL D 312
REMARK 465 ARG D 313
REMARK 465 LYS D 314
REMARK 465 ILE D 315
REMARK 465 PHE D 316
REMARK 465 ILE D 317
REMARK 465 ASN D 318
REMARK 465 THR D 319
REMARK 465 ILE D 320
REMARK 465 PRO D 321
REMARK 465 ASN D 322
REMARK 465 VAL D 323
REMARK 465 MET D 324
REMARK 465 PHE D 325
REMARK 465 PHE D 326
REMARK 465 SER D 327
REMARK 465 THR D 328
REMARK 465 MET D 329
REMARK 465 LYS D 330
REMARK 465 ARG D 331
REMARK 465 ALA D 332
REMARK 465 SER D 333
REMARK 465 LYS D 334
REMARK 465 GLU D 335
REMARK 465 LYS D 336
REMARK 465 GLN D 337
REMARK 465 GLU D 338
REMARK 465 ASN D 339
REMARK 465 LYS D 340
REMARK 465 ILE D 341
REMARK 465 PHE D 342
REMARK 465 ALA D 343
REMARK 465 ASP D 344
REMARK 465 ASP D 345
REMARK 465 ILE D 346
REMARK 465 ASP D 347
REMARK 465 ILE D 348
REMARK 465 SER D 349
REMARK 465 ASP D 350
REMARK 465 ILE D 351
REMARK 465 SER D 352
REMARK 465 GLY D 353
REMARK 465 LYS D 354
REMARK 465 GLN D 355
REMARK 465 VAL D 356
REMARK 465 THR D 357
REMARK 465 GLY D 358
REMARK 465 GLU D 359
REMARK 465 VAL D 360
REMARK 465 ILE D 361
REMARK 465 PHE D 362
REMARK 465 GLN D 363
REMARK 465 THR D 364
REMARK 465 PRO D 365
REMARK 465 LEU D 366
REMARK 465 ILE D 367
REMARK 465 LYS D 368
REMARK 465 ASN D 369
REMARK 465 PRO D 370
REMARK 465 ASP D 371
REMARK 465 VAL D 372
REMARK 465 LYS D 373
REMARK 465 MET E -16
REMARK 465 VAL E -15
REMARK 465 LEU E -14
REMARK 465 THR E -13
REMARK 465 LEU E -12
REMARK 465 LEU E -11
REMARK 465 LEU E -10
REMARK 465 ILE E -9
REMARK 465 ILE E -8
REMARK 465 CYS E -7
REMARK 465 LEU E -6
REMARK 465 ALA E -5
REMARK 465 LEU E -4
REMARK 465 GLU E -3
REMARK 465 VAL E -2
REMARK 465 ARG E -1
REMARK 465 SER E 0
REMARK 465 GLU E 165
REMARK 465 VAL E 166
REMARK 465 VAL E 167
REMARK 465 GLU E 168
REMARK 465 TRP E 169
REMARK 465 ILE E 170
REMARK 465 HIS E 171
REMARK 465 SER E 315
REMARK 465 LEU E 316
REMARK 465 SER E 317
REMARK 465 GLU E 318
REMARK 465 LYS E 319
REMARK 465 ILE E 320
REMARK 465 LYS E 321
REMARK 465 HIS E 322
REMARK 465 LEU E 323
REMARK 465 PHE E 324
REMARK 465 LEU E 325
REMARK 465 GLU E 326
REMARK 465 PHE E 327
REMARK 465 LEU E 328
REMARK 465 PRO E 329
REMARK 465 LYS E 330
REMARK 465 TYR E 331
REMARK 465 LEU E 332
REMARK 465 GLY E 333
REMARK 465 MET E 334
REMARK 465 HIS E 335
REMARK 465 LEU E 336
REMARK 465 GLU E 337
REMARK 465 PRO E 338
REMARK 465 SER E 339
REMARK 465 GLU E 340
REMARK 465 GLU E 341
REMARK 465 THR E 342
REMARK 465 PRO E 343
REMARK 465 GLU E 344
REMARK 465 LYS E 345
REMARK 465 PRO E 346
REMARK 465 GLN E 347
REMARK 465 PRO E 348
REMARK 465 ARG E 349
REMARK 465 ARG E 350
REMARK 465 ARG E 351
REMARK 465 SER E 352
REMARK 465 SER E 353
REMARK 465 PHE E 354
REMARK 465 GLY E 355
REMARK 465 ILE E 356
REMARK 465 MET E 357
REMARK 465 ILE E 358
REMARK 465 LYS E 359
REMARK 465 ALA E 360
REMARK 465 GLU E 361
REMARK 465 GLU E 362
REMARK 465 TYR E 363
REMARK 465 ILE E 364
REMARK 465 LEU E 365
REMARK 465 LYS E 366
REMARK 465 LYS E 367
REMARK 465 PRO E 368
REMARK 465 ARG E 369
REMARK 465 SER E 370
REMARK 465 GLU E 371
REMARK 465 LEU E 372
REMARK 465 MET E 373
REMARK 465 PHE E 374
REMARK 465 GLU E 375
REMARK 465 GLU E 376
REMARK 465 GLN E 377
REMARK 465 LYS E 378
REMARK 465 ASP E 379
REMARK 465 ARG E 380
REMARK 465 HIS E 381
REMARK 465 GLY E 382
REMARK 465 LEU E 383
REMARK 465 LYS E 384
REMARK 465 ARG E 385
REMARK 465 VAL E 386
REMARK 465 ASN E 387
REMARK 465 LYS E 388
REMARK 465 MET E 389
REMARK 465 THR E 390
REMARK 465 SER E 391
REMARK 465 ASP E 392
REMARK 465 ILE E 393
REMARK 465 ASP E 394
REMARK 465 ILE E 395
REMARK 465 GLY E 396
REMARK 465 THR E 397
REMARK 465 THR E 398
REMARK 465 VAL E 399
REMARK 465 ASP E 400
REMARK 465 LEU E 401
REMARK 465 TYR E 402
REMARK 465 LYS E 403
REMARK 465 ASP E 404
REMARK 465 LEU E 405
REMARK 465 ALA E 406
REMARK 465 ASN E 407
REMARK 465 PHE E 408
REMARK 465 ALA E 409
REMARK 465 PRO E 410
REMARK 465 GLU E 411
REMARK 465 ILE E 412
REMARK 465 LYS E 413
REMARK 465 PRO E 478
REMARK 465 PHE E 479
REMARK 465 PRO E 480
REMARK 465 GLY E 481
REMARK 465 ASP E 482
REMARK 465 PRO E 483
REMARK 465 ARG E 484
REMARK 465 LYS E 485
REMARK 465 TYR E 486
REMARK 465 VAL E 487
REMARK 465 PRO E 488
REMARK 465 MET F -23
REMARK 465 ILE F -22
REMARK 465 LEU F -21
REMARK 465 CYS F -20
REMARK 465 SER F -19
REMARK 465 TYR F -18
REMARK 465 TRP F -17
REMARK 465 HIS F -16
REMARK 465 VAL F -15
REMARK 465 GLY F -14
REMARK 465 LEU F -13
REMARK 465 VAL F -12
REMARK 465 LEU F -11
REMARK 465 LEU F -10
REMARK 465 LEU F -9
REMARK 465 PHE F -8
REMARK 465 SER F -7
REMARK 465 CYS F -6
REMARK 465 CYS F -5
REMARK 465 GLY F -4
REMARK 465 LEU F -3
REMARK 465 VAL F -2
REMARK 465 LEU F -1
REMARK 465 GLY F 0
REMARK 465 THR F 307
REMARK 465 MET F 308
REMARK 465 PRO F 309
REMARK 465 GLN F 310
REMARK 465 TRP F 311
REMARK 465 VAL F 312
REMARK 465 ARG F 313
REMARK 465 LYS F 314
REMARK 465 ILE F 315
REMARK 465 PHE F 316
REMARK 465 ILE F 317
REMARK 465 ASN F 318
REMARK 465 THR F 319
REMARK 465 ILE F 320
REMARK 465 PRO F 321
REMARK 465 ASN F 322
REMARK 465 VAL F 323
REMARK 465 MET F 324
REMARK 465 PHE F 325
REMARK 465 PHE F 326
REMARK 465 SER F 327
REMARK 465 THR F 328
REMARK 465 MET F 329
REMARK 465 LYS F 330
REMARK 465 ARG F 331
REMARK 465 ALA F 332
REMARK 465 SER F 333
REMARK 465 LYS F 334
REMARK 465 GLU F 335
REMARK 465 LYS F 336
REMARK 465 GLN F 337
REMARK 465 GLU F 338
REMARK 465 ASN F 339
REMARK 465 LYS F 340
REMARK 465 ILE F 341
REMARK 465 PHE F 342
REMARK 465 ALA F 343
REMARK 465 ASP F 344
REMARK 465 ASP F 345
REMARK 465 ILE F 346
REMARK 465 ASP F 347
REMARK 465 ILE F 348
REMARK 465 SER F 349
REMARK 465 ASP F 350
REMARK 465 ILE F 351
REMARK 465 SER F 352
REMARK 465 GLY F 353
REMARK 465 LYS F 354
REMARK 465 GLN F 355
REMARK 465 VAL F 356
REMARK 465 THR F 357
REMARK 465 GLY F 358
REMARK 465 GLU F 359
REMARK 465 VAL F 360
REMARK 465 ILE F 361
REMARK 465 PHE F 362
REMARK 465 GLN F 363
REMARK 465 THR F 364
REMARK 465 PRO F 365
REMARK 465 LEU F 366
REMARK 465 ILE F 367
REMARK 465 LYS F 368
REMARK 465 ASN F 369
REMARK 465 PRO F 370
REMARK 465 ASP F 371
REMARK 465 VAL F 372
REMARK 465 LYS F 373
REMARK 465 MET G -23
REMARK 465 GLU G -22
REMARK 465 ASP G -21
REMARK 465 VAL G -20
REMARK 465 ARG G -19
REMARK 465 ARG G -18
REMARK 465 MET G -17
REMARK 465 ALA G -16
REMARK 465 LEU G -15
REMARK 465 GLY G -14
REMARK 465 LEU G -13
REMARK 465 VAL G -12
REMARK 465 VAL G -11
REMARK 465 MET G -10
REMARK 465 MET G -9
REMARK 465 ALA G -8
REMARK 465 LEU G -7
REMARK 465 ALA G -6
REMARK 465 LEU G -5
REMARK 465 SER G -4
REMARK 465 GLY G -3
REMARK 465 VAL G -2
REMARK 465 GLY G -1
REMARK 465 ALA G 0
REMARK 465 LYS G 165
REMARK 465 GLY G 166
REMARK 465 GLU G 167
REMARK 465 ARG G 168
REMARK 465 GLU G 169
REMARK 465 VAL G 170
REMARK 465 LYS G 171
REMARK 465 GLU G 172
REMARK 465 ILE G 173
REMARK 465 THR G 313
REMARK 465 MET G 314
REMARK 465 PRO G 315
REMARK 465 ASN G 316
REMARK 465 TRP G 317
REMARK 465 ILE G 318
REMARK 465 ARG G 319
REMARK 465 GLN G 320
REMARK 465 ILE G 321
REMARK 465 PHE G 322
REMARK 465 ILE G 323
REMARK 465 GLU G 324
REMARK 465 THR G 325
REMARK 465 LEU G 326
REMARK 465 PRO G 327
REMARK 465 PRO G 328
REMARK 465 PHE G 329
REMARK 465 LEU G 330
REMARK 465 TRP G 331
REMARK 465 ILE G 332
REMARK 465 GLN G 333
REMARK 465 ARG G 334
REMARK 465 PRO G 335
REMARK 465 VAL G 336
REMARK 465 THR G 337
REMARK 465 THR G 338
REMARK 465 PRO G 339
REMARK 465 SER G 340
REMARK 465 PRO G 341
REMARK 465 ASP G 342
REMARK 465 SER G 343
REMARK 465 LYS G 344
REMARK 465 PRO G 345
REMARK 465 THR G 346
REMARK 465 ILE G 347
REMARK 465 ILE G 348
REMARK 465 SER G 349
REMARK 465 ARG G 350
REMARK 465 ALA G 351
REMARK 465 ASN G 352
REMARK 465 ASP G 353
REMARK 465 GLU G 354
REMARK 465 TYR G 355
REMARK 465 PHE G 356
REMARK 465 ILE G 357
REMARK 465 ARG G 358
REMARK 465 LYS G 359
REMARK 465 PRO G 360
REMARK 465 ALA G 361
REMARK 465 GLY G 362
REMARK 465 ASP G 363
REMARK 465 PHE G 364
REMARK 465 VAL G 365
REMARK 465 CYS G 366
REMARK 465 PRO G 367
REMARK 465 VAL G 368
REMARK 465 ASP G 369
REMARK 465 ASN G 370
REMARK 465 ALA G 371
REMARK 465 ARG G 372
REMARK 465 VAL G 373
REMARK 465 ALA G 374
REMARK 465 VAL G 375
REMARK 465 GLN G 376
REMARK 465 PRO G 377
REMARK 465 GLU G 378
REMARK 465 ARG G 379
REMARK 465 LEU G 380
REMARK 465 PHE G 381
REMARK 465 SER G 382
REMARK 465 GLU G 383
REMARK 465 MET G 384
REMARK 465 LYS G 385
REMARK 465 TRP G 386
REMARK 465 HIS G 387
REMARK 465 LEU G 388
REMARK 465 ASN G 389
REMARK 465 GLY G 390
REMARK 465 LEU G 391
REMARK 465 THR G 392
REMARK 465 GLN G 393
REMARK 465 PRO G 394
REMARK 465 VAL G 395
REMARK 465 THR G 396
REMARK 465 LEU G 397
REMARK 465 PRO G 398
REMARK 465 GLN G 399
REMARK 465 ASP G 400
REMARK 465 LEU G 401
REMARK 465 LYS G 402
REMARK 465 MET H -20
REMARK 465 GLY H -19
REMARK 465 ASN H -18
REMARK 465 ILE H -17
REMARK 465 HIS H -16
REMARK 465 PHE H -15
REMARK 465 VAL H -14
REMARK 465 TYR H -13
REMARK 465 LEU H -12
REMARK 465 LEU H -11
REMARK 465 ILE H -10
REMARK 465 SER H -9
REMARK 465 CYS H -8
REMARK 465 LEU H -7
REMARK 465 TYR H -6
REMARK 465 TYR H -5
REMARK 465 SER H -4
REMARK 465 GLY H -3
REMARK 465 CYS H -2
REMARK 465 SER H -1
REMARK 465 GLY H 0
REMARK 465 MET H 163
REMARK 465 THR H 164
REMARK 465 ASP H 165
REMARK 465 THR H 166
REMARK 465 ILE H 167
REMARK 465 ASP H 168
REMARK 465 GLY H 169
REMARK 465 LYS H 170
REMARK 465 ASP H 171
REMARK 465 TYR H 172
REMARK 465 PRO H 173
REMARK 465 ILE H 174
REMARK 465 GLU H 175
REMARK 465 TRP H 176
REMARK 465 ILE H 177
REMARK 465 VAL H 321
REMARK 465 LEU H 322
REMARK 465 SER H 323
REMARK 465 THR H 324
REMARK 465 ARG H 325
REMARK 465 VAL H 326
REMARK 465 LYS H 327
REMARK 465 GLN H 328
REMARK 465 ILE H 329
REMARK 465 PHE H 330
REMARK 465 LEU H 331
REMARK 465 GLU H 332
REMARK 465 LYS H 333
REMARK 465 LEU H 334
REMARK 465 PRO H 335
REMARK 465 ARG H 336
REMARK 465 ILE H 337
REMARK 465 LEU H 338
REMARK 465 HIS H 339
REMARK 465 MET H 340
REMARK 465 SER H 341
REMARK 465 ARG H 342
REMARK 465 VAL H 343
REMARK 465 ASP H 344
REMARK 465 GLU H 345
REMARK 465 ILE H 346
REMARK 465 GLU H 347
REMARK 465 GLN H 348
REMARK 465 PRO H 349
REMARK 465 ASP H 350
REMARK 465 TRP H 351
REMARK 465 GLN H 352
REMARK 465 ASN H 353
REMARK 465 ASP H 354
REMARK 465 LEU H 355
REMARK 465 LYS H 356
REMARK 465 LEU H 357
REMARK 465 ARG H 358
REMARK 465 ARG H 359
REMARK 465 SER H 360
REMARK 465 SER H 361
REMARK 465 SER H 362
REMARK 465 VAL H 363
REMARK 465 GLY H 364
REMARK 465 TYR H 365
REMARK 465 ILE H 366
REMARK 465 SER H 367
REMARK 465 LYS H 368
REMARK 465 ALA H 369
REMARK 465 GLN H 370
REMARK 465 GLU H 371
REMARK 465 TYR H 372
REMARK 465 PHE H 373
REMARK 465 ASN H 374
REMARK 465 ILE H 375
REMARK 465 LYS H 376
REMARK 465 SER H 377
REMARK 465 ARG H 378
REMARK 465 SER H 379
REMARK 465 GLU H 380
REMARK 465 LEU H 381
REMARK 465 MET H 382
REMARK 465 PHE H 383
REMARK 465 GLU H 384
REMARK 465 LYS H 385
REMARK 465 GLN H 386
REMARK 465 SER H 387
REMARK 465 GLU H 388
REMARK 465 ARG H 389
REMARK 465 HIS H 390
REMARK 465 GLY H 391
REMARK 465 LEU H 392
REMARK 465 VAL H 393
REMARK 465 PRO H 394
REMARK 465 ARG H 395
REMARK 465 VAL H 396
REMARK 465 THR H 397
REMARK 465 PRO H 398
REMARK 465 ARG H 399
REMARK 465 ILE H 400
REMARK 465 GLY H 401
REMARK 465 PHE H 402
REMARK 465 GLY H 403
REMARK 465 ASN H 404
REMARK 465 ASN H 405
REMARK 465 ASN H 406
REMARK 465 GLU H 407
REMARK 465 ASN H 408
REMARK 465 ILE H 409
REMARK 465 ALA H 410
REMARK 465 ALA H 411
REMARK 465 SER H 412
REMARK 465 ASP H 413
REMARK 465 GLN H 414
REMARK 465 LEU H 415
REMARK 465 HIS H 416
REMARK 465 ASP H 417
REMARK 465 GLU H 418
REMARK 465 ILE H 419
REMARK 465 LYS H 420
REMARK 465 PHE H 486
REMARK 465 GLU H 487
REMARK 465 GLY H 488
REMARK 465 ASP H 489
REMARK 465 PRO H 490
REMARK 465 PHE H 491
REMARK 465 ASP H 492
REMARK 465 TYR H 493
REMARK 465 SER H 494
REMARK 465 SER H 495
REMARK 465 ASP H 496
REMARK 465 HIS H 497
REMARK 465 PRO H 498
REMARK 465 ARG H 499
REMARK 465 CYS H 500
REMARK 465 ALA H 501
REMARK 465 MET I -23
REMARK 465 ILE I -22
REMARK 465 LEU I -21
REMARK 465 CYS I -20
REMARK 465 SER I -19
REMARK 465 TYR I -18
REMARK 465 TRP I -17
REMARK 465 HIS I -16
REMARK 465 VAL I -15
REMARK 465 GLY I -14
REMARK 465 LEU I -13
REMARK 465 VAL I -12
REMARK 465 LEU I -11
REMARK 465 LEU I -10
REMARK 465 LEU I -9
REMARK 465 PHE I -8
REMARK 465 SER I -7
REMARK 465 CYS I -6
REMARK 465 CYS I -5
REMARK 465 GLY I -4
REMARK 465 LEU I -3
REMARK 465 VAL I -2
REMARK 465 LEU I -1
REMARK 465 GLY I 0
REMARK 465 THR I 307
REMARK 465 MET I 308
REMARK 465 PRO I 309
REMARK 465 GLN I 310
REMARK 465 TRP I 311
REMARK 465 VAL I 312
REMARK 465 ARG I 313
REMARK 465 LYS I 314
REMARK 465 ILE I 315
REMARK 465 PHE I 316
REMARK 465 ILE I 317
REMARK 465 ASN I 318
REMARK 465 THR I 319
REMARK 465 ILE I 320
REMARK 465 PRO I 321
REMARK 465 ASN I 322
REMARK 465 VAL I 323
REMARK 465 MET I 324
REMARK 465 PHE I 325
REMARK 465 PHE I 326
REMARK 465 SER I 327
REMARK 465 THR I 328
REMARK 465 MET I 329
REMARK 465 LYS I 330
REMARK 465 ARG I 331
REMARK 465 ALA I 332
REMARK 465 SER I 333
REMARK 465 LYS I 334
REMARK 465 GLU I 335
REMARK 465 LYS I 336
REMARK 465 GLN I 337
REMARK 465 GLU I 338
REMARK 465 ASN I 339
REMARK 465 LYS I 340
REMARK 465 ILE I 341
REMARK 465 PHE I 342
REMARK 465 ALA I 343
REMARK 465 ASP I 344
REMARK 465 ASP I 345
REMARK 465 ILE I 346
REMARK 465 ASP I 347
REMARK 465 ILE I 348
REMARK 465 SER I 349
REMARK 465 ASP I 350
REMARK 465 ILE I 351
REMARK 465 SER I 352
REMARK 465 GLY I 353
REMARK 465 LYS I 354
REMARK 465 GLN I 355
REMARK 465 VAL I 356
REMARK 465 THR I 357
REMARK 465 GLY I 358
REMARK 465 GLU I 359
REMARK 465 VAL I 360
REMARK 465 ILE I 361
REMARK 465 PHE I 362
REMARK 465 GLN I 363
REMARK 465 THR I 364
REMARK 465 PRO I 365
REMARK 465 LEU I 366
REMARK 465 ILE I 367
REMARK 465 LYS I 368
REMARK 465 ASN I 369
REMARK 465 PRO I 370
REMARK 465 ASP I 371
REMARK 465 VAL I 372
REMARK 465 LYS I 373
REMARK 465 MET J -16
REMARK 465 VAL J -15
REMARK 465 LEU J -14
REMARK 465 THR J -13
REMARK 465 LEU J -12
REMARK 465 LEU J -11
REMARK 465 LEU J -10
REMARK 465 ILE J -9
REMARK 465 ILE J -8
REMARK 465 CYS J -7
REMARK 465 LEU J -6
REMARK 465 ALA J -5
REMARK 465 LEU J -4
REMARK 465 GLU J -3
REMARK 465 VAL J -2
REMARK 465 ARG J -1
REMARK 465 SER J 0
REMARK 465 GLU J 165
REMARK 465 VAL J 166
REMARK 465 VAL J 167
REMARK 465 GLU J 168
REMARK 465 TRP J 169
REMARK 465 ILE J 170
REMARK 465 HIS J 171
REMARK 465 SER J 315
REMARK 465 LEU J 316
REMARK 465 SER J 317
REMARK 465 GLU J 318
REMARK 465 LYS J 319
REMARK 465 ILE J 320
REMARK 465 LYS J 321
REMARK 465 HIS J 322
REMARK 465 LEU J 323
REMARK 465 PHE J 324
REMARK 465 LEU J 325
REMARK 465 GLU J 326
REMARK 465 PHE J 327
REMARK 465 LEU J 328
REMARK 465 PRO J 329
REMARK 465 LYS J 330
REMARK 465 TYR J 331
REMARK 465 LEU J 332
REMARK 465 GLY J 333
REMARK 465 MET J 334
REMARK 465 HIS J 335
REMARK 465 LEU J 336
REMARK 465 GLU J 337
REMARK 465 PRO J 338
REMARK 465 SER J 339
REMARK 465 GLU J 340
REMARK 465 GLU J 341
REMARK 465 THR J 342
REMARK 465 PRO J 343
REMARK 465 GLU J 344
REMARK 465 LYS J 345
REMARK 465 PRO J 346
REMARK 465 GLN J 347
REMARK 465 PRO J 348
REMARK 465 ARG J 349
REMARK 465 ARG J 350
REMARK 465 ARG J 351
REMARK 465 SER J 352
REMARK 465 SER J 353
REMARK 465 PHE J 354
REMARK 465 GLY J 355
REMARK 465 ILE J 356
REMARK 465 MET J 357
REMARK 465 ILE J 358
REMARK 465 LYS J 359
REMARK 465 ALA J 360
REMARK 465 GLU J 361
REMARK 465 GLU J 362
REMARK 465 TYR J 363
REMARK 465 ILE J 364
REMARK 465 LEU J 365
REMARK 465 LYS J 366
REMARK 465 LYS J 367
REMARK 465 PRO J 368
REMARK 465 ARG J 369
REMARK 465 SER J 370
REMARK 465 GLU J 371
REMARK 465 LEU J 372
REMARK 465 MET J 373
REMARK 465 PHE J 374
REMARK 465 GLU J 375
REMARK 465 GLU J 376
REMARK 465 GLN J 377
REMARK 465 LYS J 378
REMARK 465 ASP J 379
REMARK 465 ARG J 380
REMARK 465 HIS J 381
REMARK 465 GLY J 382
REMARK 465 LEU J 383
REMARK 465 LYS J 384
REMARK 465 ARG J 385
REMARK 465 VAL J 386
REMARK 465 ASN J 387
REMARK 465 LYS J 388
REMARK 465 MET J 389
REMARK 465 THR J 390
REMARK 465 SER J 391
REMARK 465 ASP J 392
REMARK 465 ILE J 393
REMARK 465 ASP J 394
REMARK 465 ILE J 395
REMARK 465 GLY J 396
REMARK 465 THR J 397
REMARK 465 THR J 398
REMARK 465 VAL J 399
REMARK 465 ASP J 400
REMARK 465 LEU J 401
REMARK 465 TYR J 402
REMARK 465 LYS J 403
REMARK 465 ASP J 404
REMARK 465 LEU J 405
REMARK 465 ALA J 406
REMARK 465 ASN J 407
REMARK 465 PHE J 408
REMARK 465 ALA J 409
REMARK 465 PRO J 410
REMARK 465 GLU J 411
REMARK 465 ILE J 412
REMARK 465 LYS J 413
REMARK 465 PRO J 478
REMARK 465 PHE J 479
REMARK 465 PRO J 480
REMARK 465 GLY J 481
REMARK 465 ASP J 482
REMARK 465 PRO J 483
REMARK 465 ARG J 484
REMARK 465 LYS J 485
REMARK 465 TYR J 486
REMARK 465 VAL J 487
REMARK 465 PRO J 488
REMARK 465 MET K -23
REMARK 465 ILE K -22
REMARK 465 LEU K -21
REMARK 465 CYS K -20
REMARK 465 SER K -19
REMARK 465 TYR K -18
REMARK 465 TRP K -17
REMARK 465 HIS K -16
REMARK 465 VAL K -15
REMARK 465 GLY K -14
REMARK 465 LEU K -13
REMARK 465 VAL K -12
REMARK 465 LEU K -11
REMARK 465 LEU K -10
REMARK 465 LEU K -9
REMARK 465 PHE K -8
REMARK 465 SER K -7
REMARK 465 CYS K -6
REMARK 465 CYS K -5
REMARK 465 GLY K -4
REMARK 465 LEU K -3
REMARK 465 VAL K -2
REMARK 465 LEU K -1
REMARK 465 GLY K 0
REMARK 465 THR K 307
REMARK 465 MET K 308
REMARK 465 PRO K 309
REMARK 465 GLN K 310
REMARK 465 TRP K 311
REMARK 465 VAL K 312
REMARK 465 ARG K 313
REMARK 465 LYS K 314
REMARK 465 ILE K 315
REMARK 465 PHE K 316
REMARK 465 ILE K 317
REMARK 465 ASN K 318
REMARK 465 THR K 319
REMARK 465 ILE K 320
REMARK 465 PRO K 321
REMARK 465 ASN K 322
REMARK 465 VAL K 323
REMARK 465 MET K 324
REMARK 465 PHE K 325
REMARK 465 PHE K 326
REMARK 465 SER K 327
REMARK 465 THR K 328
REMARK 465 MET K 329
REMARK 465 LYS K 330
REMARK 465 ARG K 331
REMARK 465 ALA K 332
REMARK 465 SER K 333
REMARK 465 LYS K 334
REMARK 465 GLU K 335
REMARK 465 LYS K 336
REMARK 465 GLN K 337
REMARK 465 GLU K 338
REMARK 465 ASN K 339
REMARK 465 LYS K 340
REMARK 465 ILE K 341
REMARK 465 PHE K 342
REMARK 465 ALA K 343
REMARK 465 ASP K 344
REMARK 465 ASP K 345
REMARK 465 ILE K 346
REMARK 465 ASP K 347
REMARK 465 ILE K 348
REMARK 465 SER K 349
REMARK 465 ASP K 350
REMARK 465 ILE K 351
REMARK 465 SER K 352
REMARK 465 GLY K 353
REMARK 465 LYS K 354
REMARK 465 GLN K 355
REMARK 465 VAL K 356
REMARK 465 THR K 357
REMARK 465 GLY K 358
REMARK 465 GLU K 359
REMARK 465 VAL K 360
REMARK 465 ILE K 361
REMARK 465 PHE K 362
REMARK 465 GLN K 363
REMARK 465 THR K 364
REMARK 465 PRO K 365
REMARK 465 LEU K 366
REMARK 465 ILE K 367
REMARK 465 LYS K 368
REMARK 465 ASN K 369
REMARK 465 PRO K 370
REMARK 465 ASP K 371
REMARK 465 VAL K 372
REMARK 465 LYS K 373
REMARK 465 MET L -23
REMARK 465 GLU L -22
REMARK 465 ASP L -21
REMARK 465 VAL L -20
REMARK 465 ARG L -19
REMARK 465 ARG L -18
REMARK 465 MET L -17
REMARK 465 ALA L -16
REMARK 465 LEU L -15
REMARK 465 GLY L -14
REMARK 465 LEU L -13
REMARK 465 VAL L -12
REMARK 465 VAL L -11
REMARK 465 MET L -10
REMARK 465 MET L -9
REMARK 465 ALA L -8
REMARK 465 LEU L -7
REMARK 465 ALA L -6
REMARK 465 LEU L -5
REMARK 465 SER L -4
REMARK 465 GLY L -3
REMARK 465 VAL L -2
REMARK 465 GLY L -1
REMARK 465 ALA L 0
REMARK 465 LYS L 165
REMARK 465 GLY L 166
REMARK 465 GLU L 167
REMARK 465 ARG L 168
REMARK 465 GLU L 169
REMARK 465 VAL L 170
REMARK 465 LYS L 171
REMARK 465 GLU L 172
REMARK 465 ILE L 173
REMARK 465 THR L 313
REMARK 465 MET L 314
REMARK 465 PRO L 315
REMARK 465 ASN L 316
REMARK 465 TRP L 317
REMARK 465 ILE L 318
REMARK 465 ARG L 319
REMARK 465 GLN L 320
REMARK 465 ILE L 321
REMARK 465 PHE L 322
REMARK 465 ILE L 323
REMARK 465 GLU L 324
REMARK 465 THR L 325
REMARK 465 LEU L 326
REMARK 465 PRO L 327
REMARK 465 PRO L 328
REMARK 465 PHE L 329
REMARK 465 LEU L 330
REMARK 465 TRP L 331
REMARK 465 ILE L 332
REMARK 465 GLN L 333
REMARK 465 ARG L 334
REMARK 465 PRO L 335
REMARK 465 VAL L 336
REMARK 465 THR L 337
REMARK 465 THR L 338
REMARK 465 PRO L 339
REMARK 465 SER L 340
REMARK 465 PRO L 341
REMARK 465 ASP L 342
REMARK 465 SER L 343
REMARK 465 LYS L 344
REMARK 465 PRO L 345
REMARK 465 THR L 346
REMARK 465 ILE L 347
REMARK 465 ILE L 348
REMARK 465 SER L 349
REMARK 465 ARG L 350
REMARK 465 ALA L 351
REMARK 465 ASN L 352
REMARK 465 ASP L 353
REMARK 465 GLU L 354
REMARK 465 TYR L 355
REMARK 465 PHE L 356
REMARK 465 ILE L 357
REMARK 465 ARG L 358
REMARK 465 LYS L 359
REMARK 465 PRO L 360
REMARK 465 ALA L 361
REMARK 465 GLY L 362
REMARK 465 ASP L 363
REMARK 465 PHE L 364
REMARK 465 VAL L 365
REMARK 465 CYS L 366
REMARK 465 PRO L 367
REMARK 465 VAL L 368
REMARK 465 ASP L 369
REMARK 465 ASN L 370
REMARK 465 ALA L 371
REMARK 465 ARG L 372
REMARK 465 VAL L 373
REMARK 465 ALA L 374
REMARK 465 VAL L 375
REMARK 465 GLN L 376
REMARK 465 PRO L 377
REMARK 465 GLU L 378
REMARK 465 ARG L 379
REMARK 465 LEU L 380
REMARK 465 PHE L 381
REMARK 465 SER L 382
REMARK 465 GLU L 383
REMARK 465 MET L 384
REMARK 465 LYS L 385
REMARK 465 TRP L 386
REMARK 465 HIS L 387
REMARK 465 LEU L 388
REMARK 465 ASN L 389
REMARK 465 GLY L 390
REMARK 465 LEU L 391
REMARK 465 THR L 392
REMARK 465 GLN L 393
REMARK 465 PRO L 394
REMARK 465 VAL L 395
REMARK 465 THR L 396
REMARK 465 LEU L 397
REMARK 465 PRO L 398
REMARK 465 GLN L 399
REMARK 465 ASP L 400
REMARK 465 LEU L 401
REMARK 465 LYS L 402
REMARK 465 MET M -20
REMARK 465 GLY M -19
REMARK 465 ASN M -18
REMARK 465 ILE M -17
REMARK 465 HIS M -16
REMARK 465 PHE M -15
REMARK 465 VAL M -14
REMARK 465 TYR M -13
REMARK 465 LEU M -12
REMARK 465 LEU M -11
REMARK 465 ILE M -10
REMARK 465 SER M -9
REMARK 465 CYS M -8
REMARK 465 LEU M -7
REMARK 465 TYR M -6
REMARK 465 TYR M -5
REMARK 465 SER M -4
REMARK 465 GLY M -3
REMARK 465 CYS M -2
REMARK 465 SER M -1
REMARK 465 GLY M 0
REMARK 465 MET M 163
REMARK 465 THR M 164
REMARK 465 ASP M 165
REMARK 465 THR M 166
REMARK 465 ILE M 167
REMARK 465 ASP M 168
REMARK 465 GLY M 169
REMARK 465 LYS M 170
REMARK 465 ASP M 171
REMARK 465 TYR M 172
REMARK 465 PRO M 173
REMARK 465 ILE M 174
REMARK 465 GLU M 175
REMARK 465 TRP M 176
REMARK 465 ILE M 177
REMARK 465 VAL M 321
REMARK 465 LEU M 322
REMARK 465 SER M 323
REMARK 465 THR M 324
REMARK 465 ARG M 325
REMARK 465 VAL M 326
REMARK 465 LYS M 327
REMARK 465 GLN M 328
REMARK 465 ILE M 329
REMARK 465 PHE M 330
REMARK 465 LEU M 331
REMARK 465 GLU M 332
REMARK 465 LYS M 333
REMARK 465 LEU M 334
REMARK 465 PRO M 335
REMARK 465 ARG M 336
REMARK 465 ILE M 337
REMARK 465 LEU M 338
REMARK 465 HIS M 339
REMARK 465 MET M 340
REMARK 465 SER M 341
REMARK 465 ARG M 342
REMARK 465 VAL M 343
REMARK 465 ASP M 344
REMARK 465 GLU M 345
REMARK 465 ILE M 346
REMARK 465 GLU M 347
REMARK 465 GLN M 348
REMARK 465 PRO M 349
REMARK 465 ASP M 350
REMARK 465 TRP M 351
REMARK 465 GLN M 352
REMARK 465 ASN M 353
REMARK 465 ASP M 354
REMARK 465 LEU M 355
REMARK 465 LYS M 356
REMARK 465 LEU M 357
REMARK 465 ARG M 358
REMARK 465 ARG M 359
REMARK 465 SER M 360
REMARK 465 SER M 361
REMARK 465 SER M 362
REMARK 465 VAL M 363
REMARK 465 GLY M 364
REMARK 465 TYR M 365
REMARK 465 ILE M 366
REMARK 465 SER M 367
REMARK 465 LYS M 368
REMARK 465 ALA M 369
REMARK 465 GLN M 370
REMARK 465 GLU M 371
REMARK 465 TYR M 372
REMARK 465 PHE M 373
REMARK 465 ASN M 374
REMARK 465 ILE M 375
REMARK 465 LYS M 376
REMARK 465 SER M 377
REMARK 465 ARG M 378
REMARK 465 SER M 379
REMARK 465 GLU M 380
REMARK 465 LEU M 381
REMARK 465 MET M 382
REMARK 465 PHE M 383
REMARK 465 GLU M 384
REMARK 465 LYS M 385
REMARK 465 GLN M 386
REMARK 465 SER M 387
REMARK 465 GLU M 388
REMARK 465 ARG M 389
REMARK 465 HIS M 390
REMARK 465 GLY M 391
REMARK 465 LEU M 392
REMARK 465 VAL M 393
REMARK 465 PRO M 394
REMARK 465 ARG M 395
REMARK 465 VAL M 396
REMARK 465 THR M 397
REMARK 465 PRO M 398
REMARK 465 ARG M 399
REMARK 465 ILE M 400
REMARK 465 GLY M 401
REMARK 465 PHE M 402
REMARK 465 GLY M 403
REMARK 465 ASN M 404
REMARK 465 ASN M 405
REMARK 465 ASN M 406
REMARK 465 GLU M 407
REMARK 465 ASN M 408
REMARK 465 ILE M 409
REMARK 465 ALA M 410
REMARK 465 ALA M 411
REMARK 465 SER M 412
REMARK 465 ASP M 413
REMARK 465 GLN M 414
REMARK 465 LEU M 415
REMARK 465 HIS M 416
REMARK 465 ASP M 417
REMARK 465 GLU M 418
REMARK 465 ILE M 419
REMARK 465 LYS M 420
REMARK 465 PHE M 486
REMARK 465 GLU M 487
REMARK 465 GLY M 488
REMARK 465 ASP M 489
REMARK 465 PRO M 490
REMARK 465 PHE M 491
REMARK 465 ASP M 492
REMARK 465 TYR M 493
REMARK 465 SER M 494
REMARK 465 SER M 495
REMARK 465 ASP M 496
REMARK 465 HIS M 497
REMARK 465 PRO M 498
REMARK 465 ARG M 499
REMARK 465 CYS M 500
REMARK 465 ALA M 501
REMARK 465 MET N -23
REMARK 465 ILE N -22
REMARK 465 LEU N -21
REMARK 465 CYS N -20
REMARK 465 SER N -19
REMARK 465 TYR N -18
REMARK 465 TRP N -17
REMARK 465 HIS N -16
REMARK 465 VAL N -15
REMARK 465 GLY N -14
REMARK 465 LEU N -13
REMARK 465 VAL N -12
REMARK 465 LEU N -11
REMARK 465 LEU N -10
REMARK 465 LEU N -9
REMARK 465 PHE N -8
REMARK 465 SER N -7
REMARK 465 CYS N -6
REMARK 465 CYS N -5
REMARK 465 GLY N -4
REMARK 465 LEU N -3
REMARK 465 VAL N -2
REMARK 465 LEU N -1
REMARK 465 GLY N 0
REMARK 465 THR N 307
REMARK 465 MET N 308
REMARK 465 PRO N 309
REMARK 465 GLN N 310
REMARK 465 TRP N 311
REMARK 465 VAL N 312
REMARK 465 ARG N 313
REMARK 465 LYS N 314
REMARK 465 ILE N 315
REMARK 465 PHE N 316
REMARK 465 ILE N 317
REMARK 465 ASN N 318
REMARK 465 THR N 319
REMARK 465 ILE N 320
REMARK 465 PRO N 321
REMARK 465 ASN N 322
REMARK 465 VAL N 323
REMARK 465 MET N 324
REMARK 465 PHE N 325
REMARK 465 PHE N 326
REMARK 465 SER N 327
REMARK 465 THR N 328
REMARK 465 MET N 329
REMARK 465 LYS N 330
REMARK 465 ARG N 331
REMARK 465 ALA N 332
REMARK 465 SER N 333
REMARK 465 LYS N 334
REMARK 465 GLU N 335
REMARK 465 LYS N 336
REMARK 465 GLN N 337
REMARK 465 GLU N 338
REMARK 465 ASN N 339
REMARK 465 LYS N 340
REMARK 465 ILE N 341
REMARK 465 PHE N 342
REMARK 465 ALA N 343
REMARK 465 ASP N 344
REMARK 465 ASP N 345
REMARK 465 ILE N 346
REMARK 465 ASP N 347
REMARK 465 ILE N 348
REMARK 465 SER N 349
REMARK 465 ASP N 350
REMARK 465 ILE N 351
REMARK 465 SER N 352
REMARK 465 GLY N 353
REMARK 465 LYS N 354
REMARK 465 GLN N 355
REMARK 465 VAL N 356
REMARK 465 THR N 357
REMARK 465 GLY N 358
REMARK 465 GLU N 359
REMARK 465 VAL N 360
REMARK 465 ILE N 361
REMARK 465 PHE N 362
REMARK 465 GLN N 363
REMARK 465 THR N 364
REMARK 465 PRO N 365
REMARK 465 LEU N 366
REMARK 465 ILE N 367
REMARK 465 LYS N 368
REMARK 465 ASN N 369
REMARK 465 PRO N 370
REMARK 465 ASP N 371
REMARK 465 VAL N 372
REMARK 465 LYS N 373
REMARK 465 MET O -16
REMARK 465 VAL O -15
REMARK 465 LEU O -14
REMARK 465 THR O -13
REMARK 465 LEU O -12
REMARK 465 LEU O -11
REMARK 465 LEU O -10
REMARK 465 ILE O -9
REMARK 465 ILE O -8
REMARK 465 CYS O -7
REMARK 465 LEU O -6
REMARK 465 ALA O -5
REMARK 465 LEU O -4
REMARK 465 GLU O -3
REMARK 465 VAL O -2
REMARK 465 ARG O -1
REMARK 465 SER O 0
REMARK 465 GLU O 165
REMARK 465 VAL O 166
REMARK 465 VAL O 167
REMARK 465 GLU O 168
REMARK 465 TRP O 169
REMARK 465 ILE O 170
REMARK 465 HIS O 171
REMARK 465 SER O 315
REMARK 465 LEU O 316
REMARK 465 SER O 317
REMARK 465 GLU O 318
REMARK 465 LYS O 319
REMARK 465 ILE O 320
REMARK 465 LYS O 321
REMARK 465 HIS O 322
REMARK 465 LEU O 323
REMARK 465 PHE O 324
REMARK 465 LEU O 325
REMARK 465 GLU O 326
REMARK 465 PHE O 327
REMARK 465 LEU O 328
REMARK 465 PRO O 329
REMARK 465 LYS O 330
REMARK 465 TYR O 331
REMARK 465 LEU O 332
REMARK 465 GLY O 333
REMARK 465 MET O 334
REMARK 465 HIS O 335
REMARK 465 LEU O 336
REMARK 465 GLU O 337
REMARK 465 PRO O 338
REMARK 465 SER O 339
REMARK 465 GLU O 340
REMARK 465 GLU O 341
REMARK 465 THR O 342
REMARK 465 PRO O 343
REMARK 465 GLU O 344
REMARK 465 LYS O 345
REMARK 465 PRO O 346
REMARK 465 GLN O 347
REMARK 465 PRO O 348
REMARK 465 ARG O 349
REMARK 465 ARG O 350
REMARK 465 ARG O 351
REMARK 465 SER O 352
REMARK 465 SER O 353
REMARK 465 PHE O 354
REMARK 465 GLY O 355
REMARK 465 ILE O 356
REMARK 465 MET O 357
REMARK 465 ILE O 358
REMARK 465 LYS O 359
REMARK 465 ALA O 360
REMARK 465 GLU O 361
REMARK 465 GLU O 362
REMARK 465 TYR O 363
REMARK 465 ILE O 364
REMARK 465 LEU O 365
REMARK 465 LYS O 366
REMARK 465 LYS O 367
REMARK 465 PRO O 368
REMARK 465 ARG O 369
REMARK 465 SER O 370
REMARK 465 GLU O 371
REMARK 465 LEU O 372
REMARK 465 MET O 373
REMARK 465 PHE O 374
REMARK 465 GLU O 375
REMARK 465 GLU O 376
REMARK 465 GLN O 377
REMARK 465 LYS O 378
REMARK 465 ASP O 379
REMARK 465 ARG O 380
REMARK 465 HIS O 381
REMARK 465 GLY O 382
REMARK 465 LEU O 383
REMARK 465 LYS O 384
REMARK 465 ARG O 385
REMARK 465 VAL O 386
REMARK 465 ASN O 387
REMARK 465 LYS O 388
REMARK 465 MET O 389
REMARK 465 THR O 390
REMARK 465 SER O 391
REMARK 465 ASP O 392
REMARK 465 ILE O 393
REMARK 465 ASP O 394
REMARK 465 ILE O 395
REMARK 465 GLY O 396
REMARK 465 THR O 397
REMARK 465 THR O 398
REMARK 465 VAL O 399
REMARK 465 ASP O 400
REMARK 465 LEU O 401
REMARK 465 TYR O 402
REMARK 465 LYS O 403
REMARK 465 ASP O 404
REMARK 465 LEU O 405
REMARK 465 ALA O 406
REMARK 465 ASN O 407
REMARK 465 PHE O 408
REMARK 465 ALA O 409
REMARK 465 PRO O 410
REMARK 465 GLU O 411
REMARK 465 ILE O 412
REMARK 465 LYS O 413
REMARK 465 PRO O 478
REMARK 465 PHE O 479
REMARK 465 PRO O 480
REMARK 465 GLY O 481
REMARK 465 ASP O 482
REMARK 465 PRO O 483
REMARK 465 ARG O 484
REMARK 465 LYS O 485
REMARK 465 TYR O 486
REMARK 465 VAL O 487
REMARK 465 PRO O 488
REMARK 465 MET P -23
REMARK 465 ILE P -22
REMARK 465 LEU P -21
REMARK 465 CYS P -20
REMARK 465 SER P -19
REMARK 465 TYR P -18
REMARK 465 TRP P -17
REMARK 465 HIS P -16
REMARK 465 VAL P -15
REMARK 465 GLY P -14
REMARK 465 LEU P -13
REMARK 465 VAL P -12
REMARK 465 LEU P -11
REMARK 465 LEU P -10
REMARK 465 LEU P -9
REMARK 465 PHE P -8
REMARK 465 SER P -7
REMARK 465 CYS P -6
REMARK 465 CYS P -5
REMARK 465 GLY P -4
REMARK 465 LEU P -3
REMARK 465 VAL P -2
REMARK 465 LEU P -1
REMARK 465 GLY P 0
REMARK 465 THR P 307
REMARK 465 MET P 308
REMARK 465 PRO P 309
REMARK 465 GLN P 310
REMARK 465 TRP P 311
REMARK 465 VAL P 312
REMARK 465 ARG P 313
REMARK 465 LYS P 314
REMARK 465 ILE P 315
REMARK 465 PHE P 316
REMARK 465 ILE P 317
REMARK 465 ASN P 318
REMARK 465 THR P 319
REMARK 465 ILE P 320
REMARK 465 PRO P 321
REMARK 465 ASN P 322
REMARK 465 VAL P 323
REMARK 465 MET P 324
REMARK 465 PHE P 325
REMARK 465 PHE P 326
REMARK 465 SER P 327
REMARK 465 THR P 328
REMARK 465 MET P 329
REMARK 465 LYS P 330
REMARK 465 ARG P 331
REMARK 465 ALA P 332
REMARK 465 SER P 333
REMARK 465 LYS P 334
REMARK 465 GLU P 335
REMARK 465 LYS P 336
REMARK 465 GLN P 337
REMARK 465 GLU P 338
REMARK 465 ASN P 339
REMARK 465 LYS P 340
REMARK 465 ILE P 341
REMARK 465 PHE P 342
REMARK 465 ALA P 343
REMARK 465 ASP P 344
REMARK 465 ASP P 345
REMARK 465 ILE P 346
REMARK 465 ASP P 347
REMARK 465 ILE P 348
REMARK 465 SER P 349
REMARK 465 ASP P 350
REMARK 465 ILE P 351
REMARK 465 SER P 352
REMARK 465 GLY P 353
REMARK 465 LYS P 354
REMARK 465 GLN P 355
REMARK 465 VAL P 356
REMARK 465 THR P 357
REMARK 465 GLY P 358
REMARK 465 GLU P 359
REMARK 465 VAL P 360
REMARK 465 ILE P 361
REMARK 465 PHE P 362
REMARK 465 GLN P 363
REMARK 465 THR P 364
REMARK 465 PRO P 365
REMARK 465 LEU P 366
REMARK 465 ILE P 367
REMARK 465 LYS P 368
REMARK 465 ASN P 369
REMARK 465 PRO P 370
REMARK 465 ASP P 371
REMARK 465 VAL P 372
REMARK 465 LYS P 373
REMARK 465 MET Q -23
REMARK 465 GLU Q -22
REMARK 465 ASP Q -21
REMARK 465 VAL Q -20
REMARK 465 ARG Q -19
REMARK 465 ARG Q -18
REMARK 465 MET Q -17
REMARK 465 ALA Q -16
REMARK 465 LEU Q -15
REMARK 465 GLY Q -14
REMARK 465 LEU Q -13
REMARK 465 VAL Q -12
REMARK 465 VAL Q -11
REMARK 465 MET Q -10
REMARK 465 MET Q -9
REMARK 465 ALA Q -8
REMARK 465 LEU Q -7
REMARK 465 ALA Q -6
REMARK 465 LEU Q -5
REMARK 465 SER Q -4
REMARK 465 GLY Q -3
REMARK 465 VAL Q -2
REMARK 465 GLY Q -1
REMARK 465 ALA Q 0
REMARK 465 LYS Q 165
REMARK 465 GLY Q 166
REMARK 465 GLU Q 167
REMARK 465 ARG Q 168
REMARK 465 GLU Q 169
REMARK 465 VAL Q 170
REMARK 465 LYS Q 171
REMARK 465 GLU Q 172
REMARK 465 ILE Q 173
REMARK 465 THR Q 313
REMARK 465 MET Q 314
REMARK 465 PRO Q 315
REMARK 465 ASN Q 316
REMARK 465 TRP Q 317
REMARK 465 ILE Q 318
REMARK 465 ARG Q 319
REMARK 465 GLN Q 320
REMARK 465 ILE Q 321
REMARK 465 PHE Q 322
REMARK 465 ILE Q 323
REMARK 465 GLU Q 324
REMARK 465 THR Q 325
REMARK 465 LEU Q 326
REMARK 465 PRO Q 327
REMARK 465 PRO Q 328
REMARK 465 PHE Q 329
REMARK 465 LEU Q 330
REMARK 465 TRP Q 331
REMARK 465 ILE Q 332
REMARK 465 GLN Q 333
REMARK 465 ARG Q 334
REMARK 465 PRO Q 335
REMARK 465 VAL Q 336
REMARK 465 THR Q 337
REMARK 465 THR Q 338
REMARK 465 PRO Q 339
REMARK 465 SER Q 340
REMARK 465 PRO Q 341
REMARK 465 ASP Q 342
REMARK 465 SER Q 343
REMARK 465 LYS Q 344
REMARK 465 PRO Q 345
REMARK 465 THR Q 346
REMARK 465 ILE Q 347
REMARK 465 ILE Q 348
REMARK 465 SER Q 349
REMARK 465 ARG Q 350
REMARK 465 ALA Q 351
REMARK 465 ASN Q 352
REMARK 465 ASP Q 353
REMARK 465 GLU Q 354
REMARK 465 TYR Q 355
REMARK 465 PHE Q 356
REMARK 465 ILE Q 357
REMARK 465 ARG Q 358
REMARK 465 LYS Q 359
REMARK 465 PRO Q 360
REMARK 465 ALA Q 361
REMARK 465 GLY Q 362
REMARK 465 ASP Q 363
REMARK 465 PHE Q 364
REMARK 465 VAL Q 365
REMARK 465 CYS Q 366
REMARK 465 PRO Q 367
REMARK 465 VAL Q 368
REMARK 465 ASP Q 369
REMARK 465 ASN Q 370
REMARK 465 ALA Q 371
REMARK 465 ARG Q 372
REMARK 465 VAL Q 373
REMARK 465 ALA Q 374
REMARK 465 VAL Q 375
REMARK 465 GLN Q 376
REMARK 465 PRO Q 377
REMARK 465 GLU Q 378
REMARK 465 ARG Q 379
REMARK 465 LEU Q 380
REMARK 465 PHE Q 381
REMARK 465 SER Q 382
REMARK 465 GLU Q 383
REMARK 465 MET Q 384
REMARK 465 LYS Q 385
REMARK 465 TRP Q 386
REMARK 465 HIS Q 387
REMARK 465 LEU Q 388
REMARK 465 ASN Q 389
REMARK 465 GLY Q 390
REMARK 465 LEU Q 391
REMARK 465 THR Q 392
REMARK 465 GLN Q 393
REMARK 465 PRO Q 394
REMARK 465 VAL Q 395
REMARK 465 THR Q 396
REMARK 465 LEU Q 397
REMARK 465 PRO Q 398
REMARK 465 GLN Q 399
REMARK 465 ASP Q 400
REMARK 465 LEU Q 401
REMARK 465 LYS Q 402
REMARK 465 MET R -20
REMARK 465 GLY R -19
REMARK 465 ASN R -18
REMARK 465 ILE R -17
REMARK 465 HIS R -16
REMARK 465 PHE R -15
REMARK 465 VAL R -14
REMARK 465 TYR R -13
REMARK 465 LEU R -12
REMARK 465 LEU R -11
REMARK 465 ILE R -10
REMARK 465 SER R -9
REMARK 465 CYS R -8
REMARK 465 LEU R -7
REMARK 465 TYR R -6
REMARK 465 TYR R -5
REMARK 465 SER R -4
REMARK 465 GLY R -3
REMARK 465 CYS R -2
REMARK 465 SER R -1
REMARK 465 GLY R 0
REMARK 465 MET R 163
REMARK 465 THR R 164
REMARK 465 ASP R 165
REMARK 465 THR R 166
REMARK 465 ILE R 167
REMARK 465 ASP R 168
REMARK 465 GLY R 169
REMARK 465 LYS R 170
REMARK 465 ASP R 171
REMARK 465 TYR R 172
REMARK 465 PRO R 173
REMARK 465 ILE R 174
REMARK 465 GLU R 175
REMARK 465 TRP R 176
REMARK 465 ILE R 177
REMARK 465 VAL R 321
REMARK 465 LEU R 322
REMARK 465 SER R 323
REMARK 465 THR R 324
REMARK 465 ARG R 325
REMARK 465 VAL R 326
REMARK 465 LYS R 327
REMARK 465 GLN R 328
REMARK 465 ILE R 329
REMARK 465 PHE R 330
REMARK 465 LEU R 331
REMARK 465 GLU R 332
REMARK 465 LYS R 333
REMARK 465 LEU R 334
REMARK 465 PRO R 335
REMARK 465 ARG R 336
REMARK 465 ILE R 337
REMARK 465 LEU R 338
REMARK 465 HIS R 339
REMARK 465 MET R 340
REMARK 465 SER R 341
REMARK 465 ARG R 342
REMARK 465 VAL R 343
REMARK 465 ASP R 344
REMARK 465 GLU R 345
REMARK 465 ILE R 346
REMARK 465 GLU R 347
REMARK 465 GLN R 348
REMARK 465 PRO R 349
REMARK 465 ASP R 350
REMARK 465 TRP R 351
REMARK 465 GLN R 352
REMARK 465 ASN R 353
REMARK 465 ASP R 354
REMARK 465 LEU R 355
REMARK 465 LYS R 356
REMARK 465 LEU R 357
REMARK 465 ARG R 358
REMARK 465 ARG R 359
REMARK 465 SER R 360
REMARK 465 SER R 361
REMARK 465 SER R 362
REMARK 465 VAL R 363
REMARK 465 GLY R 364
REMARK 465 TYR R 365
REMARK 465 ILE R 366
REMARK 465 SER R 367
REMARK 465 LYS R 368
REMARK 465 ALA R 369
REMARK 465 GLN R 370
REMARK 465 GLU R 371
REMARK 465 TYR R 372
REMARK 465 PHE R 373
REMARK 465 ASN R 374
REMARK 465 ILE R 375
REMARK 465 LYS R 376
REMARK 465 SER R 377
REMARK 465 ARG R 378
REMARK 465 SER R 379
REMARK 465 GLU R 380
REMARK 465 LEU R 381
REMARK 465 MET R 382
REMARK 465 PHE R 383
REMARK 465 GLU R 384
REMARK 465 LYS R 385
REMARK 465 GLN R 386
REMARK 465 SER R 387
REMARK 465 GLU R 388
REMARK 465 ARG R 389
REMARK 465 HIS R 390
REMARK 465 GLY R 391
REMARK 465 LEU R 392
REMARK 465 VAL R 393
REMARK 465 PRO R 394
REMARK 465 ARG R 395
REMARK 465 VAL R 396
REMARK 465 THR R 397
REMARK 465 PRO R 398
REMARK 465 ARG R 399
REMARK 465 ILE R 400
REMARK 465 GLY R 401
REMARK 465 PHE R 402
REMARK 465 GLY R 403
REMARK 465 ASN R 404
REMARK 465 ASN R 405
REMARK 465 ASN R 406
REMARK 465 GLU R 407
REMARK 465 ASN R 408
REMARK 465 ILE R 409
REMARK 465 ALA R 410
REMARK 465 ALA R 411
REMARK 465 SER R 412
REMARK 465 ASP R 413
REMARK 465 GLN R 414
REMARK 465 LEU R 415
REMARK 465 HIS R 416
REMARK 465 ASP R 417
REMARK 465 GLU R 418
REMARK 465 ILE R 419
REMARK 465 LYS R 420
REMARK 465 PHE R 486
REMARK 465 GLU R 487
REMARK 465 GLY R 488
REMARK 465 ASP R 489
REMARK 465 PRO R 490
REMARK 465 PHE R 491
REMARK 465 ASP R 492
REMARK 465 TYR R 493
REMARK 465 SER R 494
REMARK 465 SER R 495
REMARK 465 ASP R 496
REMARK 465 HIS R 497
REMARK 465 PRO R 498
REMARK 465 ARG R 499
REMARK 465 CYS R 500
REMARK 465 ALA R 501
REMARK 465 MET S -23
REMARK 465 ILE S -22
REMARK 465 LEU S -21
REMARK 465 CYS S -20
REMARK 465 SER S -19
REMARK 465 TYR S -18
REMARK 465 TRP S -17
REMARK 465 HIS S -16
REMARK 465 VAL S -15
REMARK 465 GLY S -14
REMARK 465 LEU S -13
REMARK 465 VAL S -12
REMARK 465 LEU S -11
REMARK 465 LEU S -10
REMARK 465 LEU S -9
REMARK 465 PHE S -8
REMARK 465 SER S -7
REMARK 465 CYS S -6
REMARK 465 CYS S -5
REMARK 465 GLY S -4
REMARK 465 LEU S -3
REMARK 465 VAL S -2
REMARK 465 LEU S -1
REMARK 465 GLY S 0
REMARK 465 THR S 307
REMARK 465 MET S 308
REMARK 465 PRO S 309
REMARK 465 GLN S 310
REMARK 465 TRP S 311
REMARK 465 VAL S 312
REMARK 465 ARG S 313
REMARK 465 LYS S 314
REMARK 465 ILE S 315
REMARK 465 PHE S 316
REMARK 465 ILE S 317
REMARK 465 ASN S 318
REMARK 465 THR S 319
REMARK 465 ILE S 320
REMARK 465 PRO S 321
REMARK 465 ASN S 322
REMARK 465 VAL S 323
REMARK 465 MET S 324
REMARK 465 PHE S 325
REMARK 465 PHE S 326
REMARK 465 SER S 327
REMARK 465 THR S 328
REMARK 465 MET S 329
REMARK 465 LYS S 330
REMARK 465 ARG S 331
REMARK 465 ALA S 332
REMARK 465 SER S 333
REMARK 465 LYS S 334
REMARK 465 GLU S 335
REMARK 465 LYS S 336
REMARK 465 GLN S 337
REMARK 465 GLU S 338
REMARK 465 ASN S 339
REMARK 465 LYS S 340
REMARK 465 ILE S 341
REMARK 465 PHE S 342
REMARK 465 ALA S 343
REMARK 465 ASP S 344
REMARK 465 ASP S 345
REMARK 465 ILE S 346
REMARK 465 ASP S 347
REMARK 465 ILE S 348
REMARK 465 SER S 349
REMARK 465 ASP S 350
REMARK 465 ILE S 351
REMARK 465 SER S 352
REMARK 465 GLY S 353
REMARK 465 LYS S 354
REMARK 465 GLN S 355
REMARK 465 VAL S 356
REMARK 465 THR S 357
REMARK 465 GLY S 358
REMARK 465 GLU S 359
REMARK 465 VAL S 360
REMARK 465 ILE S 361
REMARK 465 PHE S 362
REMARK 465 GLN S 363
REMARK 465 THR S 364
REMARK 465 PRO S 365
REMARK 465 LEU S 366
REMARK 465 ILE S 367
REMARK 465 LYS S 368
REMARK 465 ASN S 369
REMARK 465 PRO S 370
REMARK 465 ASP S 371
REMARK 465 VAL S 372
REMARK 465 LYS S 373
REMARK 465 MET T -16
REMARK 465 VAL T -15
REMARK 465 LEU T -14
REMARK 465 THR T -13
REMARK 465 LEU T -12
REMARK 465 LEU T -11
REMARK 465 LEU T -10
REMARK 465 ILE T -9
REMARK 465 ILE T -8
REMARK 465 CYS T -7
REMARK 465 LEU T -6
REMARK 465 ALA T -5
REMARK 465 LEU T -4
REMARK 465 GLU T -3
REMARK 465 VAL T -2
REMARK 465 ARG T -1
REMARK 465 SER T 0
REMARK 465 GLU T 165
REMARK 465 VAL T 166
REMARK 465 VAL T 167
REMARK 465 GLU T 168
REMARK 465 TRP T 169
REMARK 465 ILE T 170
REMARK 465 HIS T 171
REMARK 465 SER T 315
REMARK 465 LEU T 316
REMARK 465 SER T 317
REMARK 465 GLU T 318
REMARK 465 LYS T 319
REMARK 465 ILE T 320
REMARK 465 LYS T 321
REMARK 465 HIS T 322
REMARK 465 LEU T 323
REMARK 465 PHE T 324
REMARK 465 LEU T 325
REMARK 465 GLU T 326
REMARK 465 PHE T 327
REMARK 465 LEU T 328
REMARK 465 PRO T 329
REMARK 465 LYS T 330
REMARK 465 TYR T 331
REMARK 465 LEU T 332
REMARK 465 GLY T 333
REMARK 465 MET T 334
REMARK 465 HIS T 335
REMARK 465 LEU T 336
REMARK 465 GLU T 337
REMARK 465 PRO T 338
REMARK 465 SER T 339
REMARK 465 GLU T 340
REMARK 465 GLU T 341
REMARK 465 THR T 342
REMARK 465 PRO T 343
REMARK 465 GLU T 344
REMARK 465 LYS T 345
REMARK 465 PRO T 346
REMARK 465 GLN T 347
REMARK 465 PRO T 348
REMARK 465 ARG T 349
REMARK 465 ARG T 350
REMARK 465 ARG T 351
REMARK 465 SER T 352
REMARK 465 SER T 353
REMARK 465 PHE T 354
REMARK 465 GLY T 355
REMARK 465 ILE T 356
REMARK 465 MET T 357
REMARK 465 ILE T 358
REMARK 465 LYS T 359
REMARK 465 ALA T 360
REMARK 465 GLU T 361
REMARK 465 GLU T 362
REMARK 465 TYR T 363
REMARK 465 ILE T 364
REMARK 465 LEU T 365
REMARK 465 LYS T 366
REMARK 465 LYS T 367
REMARK 465 PRO T 368
REMARK 465 ARG T 369
REMARK 465 SER T 370
REMARK 465 GLU T 371
REMARK 465 LEU T 372
REMARK 465 MET T 373
REMARK 465 PHE T 374
REMARK 465 GLU T 375
REMARK 465 GLU T 376
REMARK 465 GLN T 377
REMARK 465 LYS T 378
REMARK 465 ASP T 379
REMARK 465 ARG T 380
REMARK 465 HIS T 381
REMARK 465 GLY T 382
REMARK 465 LEU T 383
REMARK 465 LYS T 384
REMARK 465 ARG T 385
REMARK 465 VAL T 386
REMARK 465 ASN T 387
REMARK 465 LYS T 388
REMARK 465 MET T 389
REMARK 465 THR T 390
REMARK 465 SER T 391
REMARK 465 ASP T 392
REMARK 465 ILE T 393
REMARK 465 ASP T 394
REMARK 465 ILE T 395
REMARK 465 GLY T 396
REMARK 465 THR T 397
REMARK 465 THR T 398
REMARK 465 VAL T 399
REMARK 465 ASP T 400
REMARK 465 LEU T 401
REMARK 465 TYR T 402
REMARK 465 LYS T 403
REMARK 465 ASP T 404
REMARK 465 LEU T 405
REMARK 465 ALA T 406
REMARK 465 ASN T 407
REMARK 465 PHE T 408
REMARK 465 ALA T 409
REMARK 465 PRO T 410
REMARK 465 GLU T 411
REMARK 465 ILE T 412
REMARK 465 LYS T 413
REMARK 465 PRO T 478
REMARK 465 PHE T 479
REMARK 465 PRO T 480
REMARK 465 GLY T 481
REMARK 465 ASP T 482
REMARK 465 PRO T 483
REMARK 465 ARG T 484
REMARK 465 LYS T 485
REMARK 465 TYR T 486
REMARK 465 VAL T 487
REMARK 465 PRO T 488
REMARK 465 MET U -23
REMARK 465 ILE U -22
REMARK 465 LEU U -21
REMARK 465 CYS U -20
REMARK 465 SER U -19
REMARK 465 TYR U -18
REMARK 465 TRP U -17
REMARK 465 HIS U -16
REMARK 465 VAL U -15
REMARK 465 GLY U -14
REMARK 465 LEU U -13
REMARK 465 VAL U -12
REMARK 465 LEU U -11
REMARK 465 LEU U -10
REMARK 465 LEU U -9
REMARK 465 PHE U -8
REMARK 465 SER U -7
REMARK 465 CYS U -6
REMARK 465 CYS U -5
REMARK 465 GLY U -4
REMARK 465 LEU U -3
REMARK 465 VAL U -2
REMARK 465 LEU U -1
REMARK 465 GLY U 0
REMARK 465 THR U 307
REMARK 465 MET U 308
REMARK 465 PRO U 309
REMARK 465 GLN U 310
REMARK 465 TRP U 311
REMARK 465 VAL U 312
REMARK 465 ARG U 313
REMARK 465 LYS U 314
REMARK 465 ILE U 315
REMARK 465 PHE U 316
REMARK 465 ILE U 317
REMARK 465 ASN U 318
REMARK 465 THR U 319
REMARK 465 ILE U 320
REMARK 465 PRO U 321
REMARK 465 ASN U 322
REMARK 465 VAL U 323
REMARK 465 MET U 324
REMARK 465 PHE U 325
REMARK 465 PHE U 326
REMARK 465 SER U 327
REMARK 465 THR U 328
REMARK 465 MET U 329
REMARK 465 LYS U 330
REMARK 465 ARG U 331
REMARK 465 ALA U 332
REMARK 465 SER U 333
REMARK 465 LYS U 334
REMARK 465 GLU U 335
REMARK 465 LYS U 336
REMARK 465 GLN U 337
REMARK 465 GLU U 338
REMARK 465 ASN U 339
REMARK 465 LYS U 340
REMARK 465 ILE U 341
REMARK 465 PHE U 342
REMARK 465 ALA U 343
REMARK 465 ASP U 344
REMARK 465 ASP U 345
REMARK 465 ILE U 346
REMARK 465 ASP U 347
REMARK 465 ILE U 348
REMARK 465 SER U 349
REMARK 465 ASP U 350
REMARK 465 ILE U 351
REMARK 465 SER U 352
REMARK 465 GLY U 353
REMARK 465 LYS U 354
REMARK 465 GLN U 355
REMARK 465 VAL U 356
REMARK 465 THR U 357
REMARK 465 GLY U 358
REMARK 465 GLU U 359
REMARK 465 VAL U 360
REMARK 465 ILE U 361
REMARK 465 PHE U 362
REMARK 465 GLN U 363
REMARK 465 THR U 364
REMARK 465 PRO U 365
REMARK 465 LEU U 366
REMARK 465 ILE U 367
REMARK 465 LYS U 368
REMARK 465 ASN U 369
REMARK 465 PRO U 370
REMARK 465 ASP U 371
REMARK 465 VAL U 372
REMARK 465 LYS U 373
REMARK 465 MET V -23
REMARK 465 GLU V -22
REMARK 465 ASP V -21
REMARK 465 VAL V -20
REMARK 465 ARG V -19
REMARK 465 ARG V -18
REMARK 465 MET V -17
REMARK 465 ALA V -16
REMARK 465 LEU V -15
REMARK 465 GLY V -14
REMARK 465 LEU V -13
REMARK 465 VAL V -12
REMARK 465 VAL V -11
REMARK 465 MET V -10
REMARK 465 MET V -9
REMARK 465 ALA V -8
REMARK 465 LEU V -7
REMARK 465 ALA V -6
REMARK 465 LEU V -5
REMARK 465 SER V -4
REMARK 465 GLY V -3
REMARK 465 VAL V -2
REMARK 465 GLY V -1
REMARK 465 ALA V 0
REMARK 465 LYS V 165
REMARK 465 GLY V 166
REMARK 465 GLU V 167
REMARK 465 ARG V 168
REMARK 465 GLU V 169
REMARK 465 VAL V 170
REMARK 465 LYS V 171
REMARK 465 GLU V 172
REMARK 465 ILE V 173
REMARK 465 THR V 313
REMARK 465 MET V 314
REMARK 465 PRO V 315
REMARK 465 ASN V 316
REMARK 465 TRP V 317
REMARK 465 ILE V 318
REMARK 465 ARG V 319
REMARK 465 GLN V 320
REMARK 465 ILE V 321
REMARK 465 PHE V 322
REMARK 465 ILE V 323
REMARK 465 GLU V 324
REMARK 465 THR V 325
REMARK 465 LEU V 326
REMARK 465 PRO V 327
REMARK 465 PRO V 328
REMARK 465 PHE V 329
REMARK 465 LEU V 330
REMARK 465 TRP V 331
REMARK 465 ILE V 332
REMARK 465 GLN V 333
REMARK 465 ARG V 334
REMARK 465 PRO V 335
REMARK 465 VAL V 336
REMARK 465 THR V 337
REMARK 465 THR V 338
REMARK 465 PRO V 339
REMARK 465 SER V 340
REMARK 465 PRO V 341
REMARK 465 ASP V 342
REMARK 465 SER V 343
REMARK 465 LYS V 344
REMARK 465 PRO V 345
REMARK 465 THR V 346
REMARK 465 ILE V 347
REMARK 465 ILE V 348
REMARK 465 SER V 349
REMARK 465 ARG V 350
REMARK 465 ALA V 351
REMARK 465 ASN V 352
REMARK 465 ASP V 353
REMARK 465 GLU V 354
REMARK 465 TYR V 355
REMARK 465 PHE V 356
REMARK 465 ILE V 357
REMARK 465 ARG V 358
REMARK 465 LYS V 359
REMARK 465 PRO V 360
REMARK 465 ALA V 361
REMARK 465 GLY V 362
REMARK 465 ASP V 363
REMARK 465 PHE V 364
REMARK 465 VAL V 365
REMARK 465 CYS V 366
REMARK 465 PRO V 367
REMARK 465 VAL V 368
REMARK 465 ASP V 369
REMARK 465 ASN V 370
REMARK 465 ALA V 371
REMARK 465 ARG V 372
REMARK 465 VAL V 373
REMARK 465 ALA V 374
REMARK 465 VAL V 375
REMARK 465 GLN V 376
REMARK 465 PRO V 377
REMARK 465 GLU V 378
REMARK 465 ARG V 379
REMARK 465 LEU V 380
REMARK 465 PHE V 381
REMARK 465 SER V 382
REMARK 465 GLU V 383
REMARK 465 MET V 384
REMARK 465 LYS V 385
REMARK 465 TRP V 386
REMARK 465 HIS V 387
REMARK 465 LEU V 388
REMARK 465 ASN V 389
REMARK 465 GLY V 390
REMARK 465 LEU V 391
REMARK 465 THR V 392
REMARK 465 GLN V 393
REMARK 465 PRO V 394
REMARK 465 VAL V 395
REMARK 465 THR V 396
REMARK 465 LEU V 397
REMARK 465 PRO V 398
REMARK 465 GLN V 399
REMARK 465 ASP V 400
REMARK 465 LEU V 401
REMARK 465 LYS V 402
REMARK 465 MET W -20
REMARK 465 GLY W -19
REMARK 465 ASN W -18
REMARK 465 ILE W -17
REMARK 465 HIS W -16
REMARK 465 PHE W -15
REMARK 465 VAL W -14
REMARK 465 TYR W -13
REMARK 465 LEU W -12
REMARK 465 LEU W -11
REMARK 465 ILE W -10
REMARK 465 SER W -9
REMARK 465 CYS W -8
REMARK 465 LEU W -7
REMARK 465 TYR W -6
REMARK 465 TYR W -5
REMARK 465 SER W -4
REMARK 465 GLY W -3
REMARK 465 CYS W -2
REMARK 465 SER W -1
REMARK 465 GLY W 0
REMARK 465 MET W 163
REMARK 465 THR W 164
REMARK 465 ASP W 165
REMARK 465 THR W 166
REMARK 465 ILE W 167
REMARK 465 ASP W 168
REMARK 465 GLY W 169
REMARK 465 LYS W 170
REMARK 465 ASP W 171
REMARK 465 TYR W 172
REMARK 465 PRO W 173
REMARK 465 ILE W 174
REMARK 465 GLU W 175
REMARK 465 TRP W 176
REMARK 465 ILE W 177
REMARK 465 VAL W 321
REMARK 465 LEU W 322
REMARK 465 SER W 323
REMARK 465 THR W 324
REMARK 465 ARG W 325
REMARK 465 VAL W 326
REMARK 465 LYS W 327
REMARK 465 GLN W 328
REMARK 465 ILE W 329
REMARK 465 PHE W 330
REMARK 465 LEU W 331
REMARK 465 GLU W 332
REMARK 465 LYS W 333
REMARK 465 LEU W 334
REMARK 465 PRO W 335
REMARK 465 ARG W 336
REMARK 465 ILE W 337
REMARK 465 LEU W 338
REMARK 465 HIS W 339
REMARK 465 MET W 340
REMARK 465 SER W 341
REMARK 465 ARG W 342
REMARK 465 VAL W 343
REMARK 465 ASP W 344
REMARK 465 GLU W 345
REMARK 465 ILE W 346
REMARK 465 GLU W 347
REMARK 465 GLN W 348
REMARK 465 PRO W 349
REMARK 465 ASP W 350
REMARK 465 TRP W 351
REMARK 465 GLN W 352
REMARK 465 ASN W 353
REMARK 465 ASP W 354
REMARK 465 LEU W 355
REMARK 465 LYS W 356
REMARK 465 LEU W 357
REMARK 465 ARG W 358
REMARK 465 ARG W 359
REMARK 465 SER W 360
REMARK 465 SER W 361
REMARK 465 SER W 362
REMARK 465 VAL W 363
REMARK 465 GLY W 364
REMARK 465 TYR W 365
REMARK 465 ILE W 366
REMARK 465 SER W 367
REMARK 465 LYS W 368
REMARK 465 ALA W 369
REMARK 465 GLN W 370
REMARK 465 GLU W 371
REMARK 465 TYR W 372
REMARK 465 PHE W 373
REMARK 465 ASN W 374
REMARK 465 ILE W 375
REMARK 465 LYS W 376
REMARK 465 SER W 377
REMARK 465 ARG W 378
REMARK 465 SER W 379
REMARK 465 GLU W 380
REMARK 465 LEU W 381
REMARK 465 MET W 382
REMARK 465 PHE W 383
REMARK 465 GLU W 384
REMARK 465 LYS W 385
REMARK 465 GLN W 386
REMARK 465 SER W 387
REMARK 465 GLU W 388
REMARK 465 ARG W 389
REMARK 465 HIS W 390
REMARK 465 GLY W 391
REMARK 465 LEU W 392
REMARK 465 VAL W 393
REMARK 465 PRO W 394
REMARK 465 ARG W 395
REMARK 465 VAL W 396
REMARK 465 THR W 397
REMARK 465 PRO W 398
REMARK 465 ARG W 399
REMARK 465 ILE W 400
REMARK 465 GLY W 401
REMARK 465 PHE W 402
REMARK 465 GLY W 403
REMARK 465 ASN W 404
REMARK 465 ASN W 405
REMARK 465 ASN W 406
REMARK 465 GLU W 407
REMARK 465 ASN W 408
REMARK 465 ILE W 409
REMARK 465 ALA W 410
REMARK 465 ALA W 411
REMARK 465 SER W 412
REMARK 465 ASP W 413
REMARK 465 GLN W 414
REMARK 465 LEU W 415
REMARK 465 HIS W 416
REMARK 465 ASP W 417
REMARK 465 GLU W 418
REMARK 465 ILE W 419
REMARK 465 LYS W 420
REMARK 465 PHE W 486
REMARK 465 GLU W 487
REMARK 465 GLY W 488
REMARK 465 ASP W 489
REMARK 465 PRO W 490
REMARK 465 PHE W 491
REMARK 465 ASP W 492
REMARK 465 TYR W 493
REMARK 465 SER W 494
REMARK 465 SER W 495
REMARK 465 ASP W 496
REMARK 465 HIS W 497
REMARK 465 PRO W 498
REMARK 465 ARG W 499
REMARK 465 CYS W 500
REMARK 465 ALA W 501
REMARK 465 MET X -23
REMARK 465 ILE X -22
REMARK 465 LEU X -21
REMARK 465 CYS X -20
REMARK 465 SER X -19
REMARK 465 TYR X -18
REMARK 465 TRP X -17
REMARK 465 HIS X -16
REMARK 465 VAL X -15
REMARK 465 GLY X -14
REMARK 465 LEU X -13
REMARK 465 VAL X -12
REMARK 465 LEU X -11
REMARK 465 LEU X -10
REMARK 465 LEU X -9
REMARK 465 PHE X -8
REMARK 465 SER X -7
REMARK 465 CYS X -6
REMARK 465 CYS X -5
REMARK 465 GLY X -4
REMARK 465 LEU X -3
REMARK 465 VAL X -2
REMARK 465 LEU X -1
REMARK 465 GLY X 0
REMARK 465 THR X 307
REMARK 465 MET X 308
REMARK 465 PRO X 309
REMARK 465 GLN X 310
REMARK 465 TRP X 311
REMARK 465 VAL X 312
REMARK 465 ARG X 313
REMARK 465 LYS X 314
REMARK 465 ILE X 315
REMARK 465 PHE X 316
REMARK 465 ILE X 317
REMARK 465 ASN X 318
REMARK 465 THR X 319
REMARK 465 ILE X 320
REMARK 465 PRO X 321
REMARK 465 ASN X 322
REMARK 465 VAL X 323
REMARK 465 MET X 324
REMARK 465 PHE X 325
REMARK 465 PHE X 326
REMARK 465 SER X 327
REMARK 465 THR X 328
REMARK 465 MET X 329
REMARK 465 LYS X 330
REMARK 465 ARG X 331
REMARK 465 ALA X 332
REMARK 465 SER X 333
REMARK 465 LYS X 334
REMARK 465 GLU X 335
REMARK 465 LYS X 336
REMARK 465 GLN X 337
REMARK 465 GLU X 338
REMARK 465 ASN X 339
REMARK 465 LYS X 340
REMARK 465 ILE X 341
REMARK 465 PHE X 342
REMARK 465 ALA X 343
REMARK 465 ASP X 344
REMARK 465 ASP X 345
REMARK 465 ILE X 346
REMARK 465 ASP X 347
REMARK 465 ILE X 348
REMARK 465 SER X 349
REMARK 465 ASP X 350
REMARK 465 ILE X 351
REMARK 465 SER X 352
REMARK 465 GLY X 353
REMARK 465 LYS X 354
REMARK 465 GLN X 355
REMARK 465 VAL X 356
REMARK 465 THR X 357
REMARK 465 GLY X 358
REMARK 465 GLU X 359
REMARK 465 VAL X 360
REMARK 465 ILE X 361
REMARK 465 PHE X 362
REMARK 465 GLN X 363
REMARK 465 THR X 364
REMARK 465 PRO X 365
REMARK 465 LEU X 366
REMARK 465 ILE X 367
REMARK 465 LYS X 368
REMARK 465 ASN X 369
REMARK 465 PRO X 370
REMARK 465 ASP X 371
REMARK 465 VAL X 372
REMARK 465 LYS X 373
REMARK 465 MET Y -16
REMARK 465 VAL Y -15
REMARK 465 LEU Y -14
REMARK 465 THR Y -13
REMARK 465 LEU Y -12
REMARK 465 LEU Y -11
REMARK 465 LEU Y -10
REMARK 465 ILE Y -9
REMARK 465 ILE Y -8
REMARK 465 CYS Y -7
REMARK 465 LEU Y -6
REMARK 465 ALA Y -5
REMARK 465 LEU Y -4
REMARK 465 GLU Y -3
REMARK 465 VAL Y -2
REMARK 465 ARG Y -1
REMARK 465 SER Y 0
REMARK 465 GLU Y 165
REMARK 465 VAL Y 166
REMARK 465 VAL Y 167
REMARK 465 GLU Y 168
REMARK 465 TRP Y 169
REMARK 465 ILE Y 170
REMARK 465 HIS Y 171
REMARK 465 SER Y 315
REMARK 465 LEU Y 316
REMARK 465 SER Y 317
REMARK 465 GLU Y 318
REMARK 465 LYS Y 319
REMARK 465 ILE Y 320
REMARK 465 LYS Y 321
REMARK 465 HIS Y 322
REMARK 465 LEU Y 323
REMARK 465 PHE Y 324
REMARK 465 LEU Y 325
REMARK 465 GLU Y 326
REMARK 465 PHE Y 327
REMARK 465 LEU Y 328
REMARK 465 PRO Y 329
REMARK 465 LYS Y 330
REMARK 465 TYR Y 331
REMARK 465 LEU Y 332
REMARK 465 GLY Y 333
REMARK 465 MET Y 334
REMARK 465 HIS Y 335
REMARK 465 LEU Y 336
REMARK 465 GLU Y 337
REMARK 465 PRO Y 338
REMARK 465 SER Y 339
REMARK 465 GLU Y 340
REMARK 465 GLU Y 341
REMARK 465 THR Y 342
REMARK 465 PRO Y 343
REMARK 465 GLU Y 344
REMARK 465 LYS Y 345
REMARK 465 PRO Y 346
REMARK 465 GLN Y 347
REMARK 465 PRO Y 348
REMARK 465 ARG Y 349
REMARK 465 ARG Y 350
REMARK 465 ARG Y 351
REMARK 465 SER Y 352
REMARK 465 SER Y 353
REMARK 465 PHE Y 354
REMARK 465 GLY Y 355
REMARK 465 ILE Y 356
REMARK 465 MET Y 357
REMARK 465 ILE Y 358
REMARK 465 LYS Y 359
REMARK 465 ALA Y 360
REMARK 465 GLU Y 361
REMARK 465 GLU Y 362
REMARK 465 TYR Y 363
REMARK 465 ILE Y 364
REMARK 465 LEU Y 365
REMARK 465 LYS Y 366
REMARK 465 LYS Y 367
REMARK 465 PRO Y 368
REMARK 465 ARG Y 369
REMARK 465 SER Y 370
REMARK 465 GLU Y 371
REMARK 465 LEU Y 372
REMARK 465 MET Y 373
REMARK 465 PHE Y 374
REMARK 465 GLU Y 375
REMARK 465 GLU Y 376
REMARK 465 GLN Y 377
REMARK 465 LYS Y 378
REMARK 465 ASP Y 379
REMARK 465 ARG Y 380
REMARK 465 HIS Y 381
REMARK 465 GLY Y 382
REMARK 465 LEU Y 383
REMARK 465 LYS Y 384
REMARK 465 ARG Y 385
REMARK 465 VAL Y 386
REMARK 465 ASN Y 387
REMARK 465 LYS Y 388
REMARK 465 MET Y 389
REMARK 465 THR Y 390
REMARK 465 SER Y 391
REMARK 465 ASP Y 392
REMARK 465 ILE Y 393
REMARK 465 ASP Y 394
REMARK 465 ILE Y 395
REMARK 465 GLY Y 396
REMARK 465 THR Y 397
REMARK 465 THR Y 398
REMARK 465 VAL Y 399
REMARK 465 ASP Y 400
REMARK 465 LEU Y 401
REMARK 465 TYR Y 402
REMARK 465 LYS Y 403
REMARK 465 ASP Y 404
REMARK 465 LEU Y 405
REMARK 465 ALA Y 406
REMARK 465 ASN Y 407
REMARK 465 PHE Y 408
REMARK 465 ALA Y 409
REMARK 465 PRO Y 410
REMARK 465 GLU Y 411
REMARK 465 ILE Y 412
REMARK 465 LYS Y 413
REMARK 465 PRO Y 478
REMARK 465 PHE Y 479
REMARK 465 PRO Y 480
REMARK 465 GLY Y 481
REMARK 465 ASP Y 482
REMARK 465 PRO Y 483
REMARK 465 ARG Y 484
REMARK 465 LYS Y 485
REMARK 465 TYR Y 486
REMARK 465 VAL Y 487
REMARK 465 PRO Y 488
REMARK 465 MET Z -23
REMARK 465 ILE Z -22
REMARK 465 LEU Z -21
REMARK 465 CYS Z -20
REMARK 465 SER Z -19
REMARK 465 TYR Z -18
REMARK 465 TRP Z -17
REMARK 465 HIS Z -16
REMARK 465 VAL Z -15
REMARK 465 GLY Z -14
REMARK 465 LEU Z -13
REMARK 465 VAL Z -12
REMARK 465 LEU Z -11
REMARK 465 LEU Z -10
REMARK 465 LEU Z -9
REMARK 465 PHE Z -8
REMARK 465 SER Z -7
REMARK 465 CYS Z -6
REMARK 465 CYS Z -5
REMARK 465 GLY Z -4
REMARK 465 LEU Z -3
REMARK 465 VAL Z -2
REMARK 465 LEU Z -1
REMARK 465 GLY Z 0
REMARK 465 THR Z 307
REMARK 465 MET Z 308
REMARK 465 PRO Z 309
REMARK 465 GLN Z 310
REMARK 465 TRP Z 311
REMARK 465 VAL Z 312
REMARK 465 ARG Z 313
REMARK 465 LYS Z 314
REMARK 465 ILE Z 315
REMARK 465 PHE Z 316
REMARK 465 ILE Z 317
REMARK 465 ASN Z 318
REMARK 465 THR Z 319
REMARK 465 ILE Z 320
REMARK 465 PRO Z 321
REMARK 465 ASN Z 322
REMARK 465 VAL Z 323
REMARK 465 MET Z 324
REMARK 465 PHE Z 325
REMARK 465 PHE Z 326
REMARK 465 SER Z 327
REMARK 465 THR Z 328
REMARK 465 MET Z 329
REMARK 465 LYS Z 330
REMARK 465 ARG Z 331
REMARK 465 ALA Z 332
REMARK 465 SER Z 333
REMARK 465 LYS Z 334
REMARK 465 GLU Z 335
REMARK 465 LYS Z 336
REMARK 465 GLN Z 337
REMARK 465 GLU Z 338
REMARK 465 ASN Z 339
REMARK 465 LYS Z 340
REMARK 465 ILE Z 341
REMARK 465 PHE Z 342
REMARK 465 ALA Z 343
REMARK 465 ASP Z 344
REMARK 465 ASP Z 345
REMARK 465 ILE Z 346
REMARK 465 ASP Z 347
REMARK 465 ILE Z 348
REMARK 465 SER Z 349
REMARK 465 ASP Z 350
REMARK 465 ILE Z 351
REMARK 465 SER Z 352
REMARK 465 GLY Z 353
REMARK 465 LYS Z 354
REMARK 465 GLN Z 355
REMARK 465 VAL Z 356
REMARK 465 THR Z 357
REMARK 465 GLY Z 358
REMARK 465 GLU Z 359
REMARK 465 VAL Z 360
REMARK 465 ILE Z 361
REMARK 465 PHE Z 362
REMARK 465 GLN Z 363
REMARK 465 THR Z 364
REMARK 465 PRO Z 365
REMARK 465 LEU Z 366
REMARK 465 ILE Z 367
REMARK 465 LYS Z 368
REMARK 465 ASN Z 369
REMARK 465 PRO Z 370
REMARK 465 ASP Z 371
REMARK 465 VAL Z 372
REMARK 465 LYS Z 373
REMARK 470
REMARK 470 MISSING ATOM
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;
REMARK 470 I=INSERTION CODE):
REMARK 470 M RES CSSEQI ATOMS
REMARK 470 PRO 1 485 CA C O CB CG CD
REMARK 470 PHE 3 477 CA C O CB CG CD1 CD2
REMARK 470 PHE 3 477 CE1 CE2 CZ
REMARK 470 PRO C 485 CA C O CB CG CD
REMARK 470 PHE E 477 CA C O CB CG CD1 CD2
REMARK 470 PHE E 477 CE1 CE2 CZ
REMARK 470 PRO H 485 CA C O CB CG CD
REMARK 470 PHE J 477 CA C O CB CG CD1 CD2
REMARK 470 PHE J 477 CE1 CE2 CZ
REMARK 470 PRO M 485 CA C O CB CG CD
REMARK 470 PHE O 477 CA C O CB CG CD1 CD2
REMARK 470 PHE O 477 CE1 CE2 CZ
REMARK 470 PRO R 485 CA C O CB CG CD
REMARK 470 PHE T 477 CA C O CB CG CD1 CD2
REMARK 470 PHE T 477 CE1 CE2 CZ
REMARK 470 PRO W 485 CA C O CB CG CD
REMARK 470 PHE Y 477 CA C O CB CG CD1 CD2
REMARK 470 PHE Y 477 CE1 CE2 CZ
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT
REMARK 500
REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT.
REMARK 500
REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI DISTANCE
REMARK 500 O THR O 132 N PHE O 134 2.05
REMARK 500 O THR J 132 N PHE J 134 2.05
REMARK 500 O THR 3 132 N PHE 3 134 2.05
REMARK 500 O THR T 132 N PHE T 134 2.05
REMARK 500 O THR E 132 N PHE E 134 2.06
REMARK 500 O THR Y 132 N PHE Y 134 2.06
REMARK 500 O ALA R 282 O VAL R 285 2.08
REMARK 500 O ALA 1 282 O VAL 1 285 2.08
REMARK 500 O ALA W 282 O VAL W 285 2.08
REMARK 500 O ALA M 282 O VAL M 285 2.08
REMARK 500 O ALA C 282 O VAL C 285 2.09
REMARK 500 O ALA H 282 O VAL H 285 2.09
REMARK 500 O HIS P 299 O HIS P 306 2.09
REMARK 500 O HIS F 299 O HIS F 306 2.09
REMARK 500 O HIS Z 299 O HIS Z 306 2.09
REMARK 500 O HIS U 299 O HIS U 306 2.09
REMARK 500 O HIS A 299 O HIS A 306 2.09
REMARK 500 O HIS K 299 O HIS K 306 2.09
REMARK 500 CD1 ILE Z 41 OE1 GLU Z 51 2.11
REMARK 500 CD1 ILE A 41 OE1 GLU A 51 2.11
REMARK 500 CD1 ILE K 41 OE1 GLU K 51 2.11
REMARK 500 CD1 ILE U 41 OE1 GLU U 51 2.11
REMARK 500 CD1 ILE F 41 OE1 GLU F 51 2.11
REMARK 500 CD1 ILE P 41 OE1 GLU P 51 2.11
REMARK 500 CE LYS F 107 O THR G 150 2.12
REMARK 500 CE LYS U 107 O THR V 150 2.12
REMARK 500 CE LYS A 107 O THR B 150 2.12
REMARK 500 CE LYS P 107 O THR Q 150 2.12
REMARK 500 O THR 0 150 CE LYS Z 107 2.12
REMARK 500 CE LYS K 107 O THR L 150 2.12
REMARK 500 O SER K 252 CD1 PHE K 256 2.12
REMARK 500 O SER F 252 CD1 PHE F 256 2.12
REMARK 500 O SER P 252 CD1 PHE P 256 2.12
REMARK 500 O SER Z 252 CD1 PHE Z 256 2.12
REMARK 500 O SER U 252 CD1 PHE U 256 2.12
REMARK 500 O SER A 252 CD1 PHE A 256 2.12
REMARK 500 O GLN 3 245 O SER Z 302 2.12
REMARK 500 O SER U 302 O GLN Y 245 2.12
REMARK 500 O SER A 302 O GLN E 245 2.12
REMARK 500 O SER F 302 O GLN J 245 2.12
REMARK 500 O SER K 302 O GLN O 245 2.12
REMARK 500 O SER P 302 O GLN T 245 2.12
REMARK 500 CD1 LEU 3 36 OD1 ASP 3 173 2.12
REMARK 500 CD1 LEU J 36 OD1 ASP J 173 2.12
REMARK 500 CD1 LEU O 36 OD1 ASP O 173 2.12
REMARK 500 CD1 LEU E 36 OD1 ASP E 173 2.12
REMARK 500 CD1 LEU Y 36 OD1 ASP Y 173 2.12
REMARK 500 CD1 LEU T 36 OD1 ASP T 173 2.12
REMARK 500 N THR J 184 O GLN J 215 2.13
REMARK 500 N THR O 184 O GLN O 215 2.13
REMARK 500
REMARK 500 THIS ENTRY HAS 132 CLOSE CONTACTS
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: COVALENT BOND LENGTHS
REMARK 500
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT: (10X,I3,1X,2(A3,1X,A1,I4,A1,1X,A4,3X),1X,F6.3)
REMARK 500
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996
REMARK 500
REMARK 500 M RES CSSEQI ATM1 RES CSSEQI ATM2 DEVIATION
REMARK 500 THR 0 129 C ILE 0 130 N -0.193
REMARK 500 LEU 1 265 C ALA 1 266 N 0.143
REMARK 500 GLN 2 208 C ARG 2 209 N 0.175
REMARK 500 GLU 3 8 CB GLU 3 8 CG 0.124
REMARK 500 TRP A 118 CB TRP A 118 CG 0.143
REMARK 500 THR B 129 C ILE B 130 N -0.194
REMARK 500 CYS C 130 C PRO C 131 N 0.114
REMARK 500 LEU C 265 C ALA C 266 N 0.142
REMARK 500 GLN D 208 C ARG D 209 N 0.174
REMARK 500 GLU E 8 CB GLU E 8 CG 0.124
REMARK 500 TRP F 118 CB TRP F 118 CG 0.142
REMARK 500 THR G 129 C ILE G 130 N -0.193
REMARK 500 CYS H 130 C PRO H 131 N 0.114
REMARK 500 LEU H 265 C ALA H 266 N 0.143
REMARK 500 GLN I 208 C ARG I 209 N 0.174
REMARK 500 GLU J 8 CB GLU J 8 CG 0.125
REMARK 500 TRP K 118 CB TRP K 118 CG 0.142
REMARK 500 THR L 129 C ILE L 130 N -0.194
REMARK 500 LEU M 265 C ALA M 266 N 0.142
REMARK 500 GLN N 208 C ARG N 209 N 0.174
REMARK 500 GLU O 8 CB GLU O 8 CG 0.124
REMARK 500 TRP P 118 CB TRP P 118 CG 0.142
REMARK 500 THR Q 129 C ILE Q 130 N -0.193
REMARK 500 CYS R 130 C PRO R 131 N 0.115
REMARK 500 LEU R 265 C ALA R 266 N 0.142
REMARK 500 GLN S 208 C ARG S 209 N 0.174
REMARK 500 GLU T 8 CB GLU T 8 CG 0.124
REMARK 500 TRP U 118 CB TRP U 118 CG 0.143
REMARK 500 THR V 129 C ILE V 130 N -0.194
REMARK 500 CYS W 130 C PRO W 131 N 0.114
REMARK 500 LEU W 265 C ALA W 266 N 0.142
REMARK 500 GLN X 208 C ARG X 209 N 0.174
REMARK 500 GLU Y 8 CB GLU Y 8 CG 0.124
REMARK 500 TRP Z 118 CB TRP Z 118 CG 0.142
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES
REMARK 500
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)
REMARK 500
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996
REMARK 500
REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3
REMARK 500 PRO 0 17 C - N - CA ANGL. DEV. = 9.3 DEGREES
REMARK 500 ILE 1 92 O - C - N ANGL. DEV. = 10.3 DEGREES
REMARK 500 PRO 1 123 C - N - CA ANGL. DEV. = 15.3 DEGREES
REMARK 500 PRO 1 131 C - N - CA ANGL. DEV. = 11.2 DEGREES
REMARK 500 TRP 1 190 O - C - N ANGL. DEV. = 10.0 DEGREES
REMARK 500 ALA 1 266 N - CA - CB ANGL. DEV. = 14.5 DEGREES
REMARK 500 ARG 1 315 NE - CZ - NH2 ANGL. DEV. = 3.6 DEGREES
REMARK 500 CYS 2 128 CA - CB - SG ANGL. DEV. = 9.6 DEGREES
REMARK 500 ARG 2 209 NE - CZ - NH2 ANGL. DEV. = 3.2 DEGREES
REMARK 500 LEU 2 253 CA - CB - CG ANGL. DEV. = 14.0 DEGREES
REMARK 500 PRO 2 272 C - N - CA ANGL. DEV. = 11.1 DEGREES
REMARK 500 CYS 3 141 CA - CB - SG ANGL. DEV. = 9.4 DEGREES
REMARK 500 LEU 3 198 CA - CB - CG ANGL. DEV. = 16.6 DEGREES
REMARK 500 ILE 3 263 CG1 - CB - CG2 ANGL. DEV. = -14.7 DEGREES
REMARK 500 LEU 3 265 CA - CB - CG ANGL. DEV. = 14.6 DEGREES
REMARK 500 CYS A 128 CA - CB - SG ANGL. DEV. = 8.7 DEGREES
REMARK 500 TRP A 149 CA - CB - CG ANGL. DEV. = 11.4 DEGREES
REMARK 500 PRO A 197 C - N - CA ANGL. DEV. = 9.2 DEGREES
REMARK 500 ARG A 209 NE - CZ - NH2 ANGL. DEV. = 3.5 DEGREES
REMARK 500 LEU A 253 CA - CB - CG ANGL. DEV. = 13.9 DEGREES
REMARK 500 PRO B 17 C - N - CA ANGL. DEV. = 9.4 DEGREES
REMARK 500 ILE C 92 O - C - N ANGL. DEV. = 10.3 DEGREES
REMARK 500 PRO C 123 C - N - CA ANGL. DEV. = 15.3 DEGREES
REMARK 500 PRO C 131 C - N - CA ANGL. DEV. = 11.2 DEGREES
REMARK 500 TRP C 190 O - C - N ANGL. DEV. = 10.0 DEGREES
REMARK 500 ALA C 266 N - CA - CB ANGL. DEV. = 14.6 DEGREES
REMARK 500 ARG C 315 NE - CZ - NH2 ANGL. DEV. = 3.5 DEGREES
REMARK 500 CYS D 128 CA - CB - SG ANGL. DEV. = 9.6 DEGREES
REMARK 500 ARG D 209 NE - CZ - NH2 ANGL. DEV. = 3.2 DEGREES
REMARK 500 LEU D 253 CA - CB - CG ANGL. DEV. = 13.9 DEGREES
REMARK 500 PRO D 272 C - N - CA ANGL. DEV. = 11.1 DEGREES
REMARK 500 CYS E 141 CA - CB - SG ANGL. DEV. = 9.4 DEGREES
REMARK 500 LEU E 198 CA - CB - CG ANGL. DEV. = 16.5 DEGREES
REMARK 500 ILE E 263 CG1 - CB - CG2 ANGL. DEV. = -14.7 DEGREES
REMARK 500 LEU E 265 CA - CB - CG ANGL. DEV. = 14.6 DEGREES
REMARK 500 CYS F 128 CA - CB - SG ANGL. DEV. = 8.6 DEGREES
REMARK 500 TRP F 149 CA - CB - CG ANGL. DEV. = 11.4 DEGREES
REMARK 500 PRO F 197 C - N - CA ANGL. DEV. = 9.2 DEGREES
REMARK 500 ARG F 209 NE - CZ - NH2 ANGL. DEV. = 3.6 DEGREES
REMARK 500 LEU F 253 CA - CB - CG ANGL. DEV. = 13.9 DEGREES
REMARK 500 PRO G 17 C - N - CA ANGL. DEV. = 9.3 DEGREES
REMARK 500 ILE H 92 O - C - N ANGL. DEV. = 10.3 DEGREES
REMARK 500 PRO H 123 C - N - CA ANGL. DEV. = 15.3 DEGREES
REMARK 500 PRO H 131 C - N - CA ANGL. DEV. = 11.2 DEGREES
REMARK 500 TRP H 190 O - C - N ANGL. DEV. = 10.0 DEGREES
REMARK 500 ALA H 266 N - CA - CB ANGL. DEV. = 14.5 DEGREES
REMARK 500 ARG H 315 NE - CZ - NH2 ANGL. DEV. = 3.6 DEGREES
REMARK 500 CYS I 128 CA - CB - SG ANGL. DEV. = 9.5 DEGREES
REMARK 500 ARG I 209 NE - CZ - NH2 ANGL. DEV. = 3.2 DEGREES
REMARK 500 LEU I 253 CA - CB - CG ANGL. DEV. = 13.9 DEGREES
REMARK 500
REMARK 500 THIS ENTRY HAS 117 ANGLE DEVIATIONS.
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: TORSION ANGLES
REMARK 500
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)
REMARK 500
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400
REMARK 500
REMARK 500 M RES CSSEQI PSI PHI
REMARK 500 VAL 0 2 84.20 -35.86
REMARK 500 MET 0 3 24.44 48.89
REMARK 500 LEU 0 7 -71.08 -46.70
REMARK 500 SER 0 9 -71.20 -61.36
REMARK 500 PRO 0 21 33.33 -58.16
REMARK 500 THR 0 24 -157.65 60.87
REMARK 500 LYS 0 28 -164.00 68.30
REMARK 500 THR 0 38 -70.27 -91.96
REMARK 500 ALA 0 59 128.67 -176.19
REMARK 500 ASP 0 62 78.87 -106.02
REMARK 500 TYR 0 63 8.81 -64.96
REMARK 500 ASP 0 68 -120.53 -132.00
REMARK 500 LYS 0 76 -25.94 -35.79
REMARK 500 SER 0 82 -122.68 -64.13
REMARK 500 ASP 0 83 -10.23 65.08
REMARK 500 PRO 0 88 92.99 -56.93
REMARK 500 ASP 0 89 56.63 -65.49
REMARK 500 ASN 0 95 -126.49 -69.85
REMARK 500 ASN 0 96 55.36 30.62
REMARK 500 SER 0 99 175.56 -49.41
REMARK 500 ILE 0 102 31.61 77.29
REMARK 500 ASN 0 107 171.15 -49.58
REMARK 500 HIS 0 119 78.56 -118.65
REMARK 500 THR 0 129 53.68 -69.25
REMARK 500 LYS 0 131 -164.86 31.57
REMARK 500 VAL 0 132 33.56 -89.56
REMARK 500 TRP 0 139 -160.04 35.41
REMARK 500 LYS 0 147 163.57 166.19
REMARK 500 THR 0 150 -21.65 -162.65
REMARK 500 THR 0 153 95.13 -60.29
REMARK 500 SER 0 154 -36.46 -145.51
REMARK 500 VAL 0 156 150.95 159.73
REMARK 500 ALA 0 161 -117.20 -108.29
REMARK 500 ALA 0 179 33.92 -145.33
REMARK 500 GLN 0 185 9.38 -65.12
REMARK 500 TRP 0 186 -153.16 -118.31
REMARK 500 GLU 0 205 -119.13 -136.06
REMARK 500 LYS 0 216 77.86 -112.93
REMARK 500 PHE 0 219 -59.88 -140.97
REMARK 500 ALA 0 235 -72.67 -63.71
REMARK 500 ALA 0 245 71.96 -152.49
REMARK 500 GLU 0 247 -3.38 -53.45
REMARK 500 MET 0 249 -65.26 -16.78
REMARK 500 LEU 0 275 -15.06 -42.26
REMARK 500 VAL 0 277 40.45 -150.31
REMARK 500 ILE 0 279 -153.25 -153.75
REMARK 500 SER 0 282 -85.20 2.67
REMARK 500 ARG 0 307 3.50 -38.96
REMARK 500 LEU 0 415 -73.31 -47.96
REMARK 500 TYR 0 430 66.65 -117.12
REMARK 500
REMARK 500 THIS ENTRY HAS 1442 RAMACHANDRAN OUTLIERS.
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: PLANAR GROUPS
REMARK 500
REMARK 500 PLANAR GROUPS IN THE FOLLOWING RESIDUES HAVE A TOTAL
REMARK 500 RMS DISTANCE OF ALL ATOMS FROM THE BEST-FIT PLANE
REMARK 500 BY MORE THAN AN EXPECTED VALUE OF 6*RMSD, WITH AN
REMARK 500 RMSD 0.02 ANGSTROMS, OR AT LEAST ONE ATOM HAS
REMARK 500 AN RMSD GREATER THAN THIS VALUE
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 M RES CSSEQI RMS TYPE
REMARK 500 TYR 1 63 0.07 SIDE CHAIN
REMARK 500 TYR 1 74 0.08 SIDE CHAIN
REMARK 500 TYR 2 72 0.08 SIDE CHAIN
REMARK 500 TYR 2 277 0.07 SIDE CHAIN
REMARK 500 TYR C 63 0.07 SIDE CHAIN
REMARK 500 TYR C 74 0.08 SIDE CHAIN
REMARK 500 TYR D 72 0.08 SIDE CHAIN
REMARK 500 TYR D 277 0.07 SIDE CHAIN
REMARK 500 TYR H 63 0.07 SIDE CHAIN
REMARK 500 TYR H 74 0.08 SIDE CHAIN
REMARK 500 TYR I 72 0.08 SIDE CHAIN
REMARK 500 TYR I 277 0.07 SIDE CHAIN
REMARK 500 TYR M 63 0.07 SIDE CHAIN
REMARK 500 TYR M 74 0.08 SIDE CHAIN
REMARK 500 TYR N 72 0.08 SIDE CHAIN
REMARK 500 TYR N 277 0.07 SIDE CHAIN
REMARK 500 TYR R 63 0.07 SIDE CHAIN
REMARK 500 TYR R 74 0.08 SIDE CHAIN
REMARK 500 TYR S 72 0.08 SIDE CHAIN
REMARK 500 TYR S 277 0.07 SIDE CHAIN
REMARK 500 TYR W 63 0.07 SIDE CHAIN
REMARK 500 TYR W 74 0.08 SIDE CHAIN
REMARK 500 TYR X 72 0.08 SIDE CHAIN
REMARK 500 TYR X 277 0.07 SIDE CHAIN
REMARK 500
REMARK 500 REMARK: NULL
REMARK 900
REMARK 900 RELATED ENTRIES
REMARK 900 RELATED ID: EMD-2376 RELATED DB: EMDB
REMARK 900 THE STRUCTURE AND SUPER-ORGANIZATION OF ACETYLCHOLINE RECEPTOR-
REMARK 900 RAPSYN COMPLEXES
REMARK 900 RELATED ID: 4BOI RELATED DB: PDB
REMARK 900 THE STRUCTURE AND SUPER-ORGANIZATION OF ACETYLCHOLINE RECEPTOR-
REMARK 900 RAPSYN COMPLEXES CLASS A
REMARK 900 RELATED ID: 4BON RELATED DB: PDB
REMARK 900 THE STRUCTURE AND SUPER-ORGANIZATION OF ACETYLCHOLINE RECEPTOR-
REMARK 900 RAPSYN COMPLEXES CLASS B
REMARK 900 RELATED ID: 4BOO RELATED DB: PDB
REMARK 900 THE STRUCTURE AND SUPER-ORGANIZATION OF ACETYLCHOLINE RECEPTOR-
REMARK 900 RAPSYN COMPLEXES CLASS C
REMARK 900 RELATED ID: 4BOR RELATED DB: PDB
REMARK 900 THE STRUCTURE AND SUPER-ORGANIZATION OF ACETYLCHOLINE RECEPTOR-
REMARK 900 RAPSYN COMPLEXES CLASS D
REMARK 900 RELATED ID: 4BOT RELATED DB: PDB
REMARK 900 THE STRUCTURE AND SUPER-ORGANIZATION OF ACETYLCHOLINE RECEPTOR-
REMARK 900 RAPSYN COMPLEXES CLASS E
DBREF 4BOG 0 -23 469 UNP Q6S3I0 Q6S3I0_TORMA 1 493
DBREF 4BOG 1 -20 501 UNP Q6S3H8 Q6S3H8_TORMA 1 522
DBREF 4BOG 2 -23 437 UNP P02711 ACHA_TORMA 1 461
DBREF 4BOG 3 -16 488 UNP Q6S3H9 Q6S3H9_TORMA 1 505
DBREF 4BOG A -23 437 UNP P02711 ACHA_TORMA 1 461
DBREF 4BOG B -23 469 UNP Q6S3I0 Q6S3I0_TORMA 1 493
DBREF 4BOG C -20 501 UNP Q6S3H8 Q6S3H8_TORMA 1 522
DBREF 4BOG D -23 437 UNP P02711 ACHA_TORMA 1 461
DBREF 4BOG E -16 488 UNP Q6S3H9 Q6S3H9_TORMA 1 505
DBREF 4BOG F -23 437 UNP P02711 ACHA_TORMA 1 461
DBREF 4BOG G -23 469 UNP Q6S3I0 Q6S3I0_TORMA 1 493
DBREF 4BOG H -20 501 UNP Q6S3H8 Q6S3H8_TORMA 1 522
DBREF 4BOG I -23 437 UNP P02711 ACHA_TORMA 1 461
DBREF 4BOG J -16 488 UNP Q6S3H9 Q6S3H9_TORMA 1 505
DBREF 4BOG K -23 437 UNP P02711 ACHA_TORMA 1 461
DBREF 4BOG L -23 469 UNP Q6S3I0 Q6S3I0_TORMA 1 493
DBREF 4BOG M -20 501 UNP Q6S3H8 Q6S3H8_TORMA 1 522
DBREF 4BOG N -23 437 UNP P02711 ACHA_TORMA 1 461
DBREF 4BOG O -16 488 UNP Q6S3H9 Q6S3H9_TORMA 1 505
DBREF 4BOG P -23 437 UNP P02711 ACHA_TORMA 1 461
DBREF 4BOG Q -23 469 UNP Q6S3I0 Q6S3I0_TORMA 1 493
DBREF 4BOG R -20 501 UNP Q6S3H8 Q6S3H8_TORMA 1 522
DBREF 4BOG S -23 437 UNP P02711 ACHA_TORMA 1 461
DBREF 4BOG T -16 488 UNP Q6S3H9 Q6S3H9_TORMA 1 505
DBREF 4BOG U -23 437 UNP P02711 ACHA_TORMA 1 461
DBREF 4BOG V -23 469 UNP Q6S3I0 Q6S3I0_TORMA 1 493
DBREF 4BOG W -20 501 UNP Q6S3H8 Q6S3H8_TORMA 1 522
DBREF 4BOG X -23 437 UNP P02711 ACHA_TORMA 1 461
DBREF 4BOG Y -16 488 UNP Q6S3H9 Q6S3H9_TORMA 1 505
DBREF 4BOG Z -23 437 UNP P02711 ACHA_TORMA 1 461
SEQRES 1 0 493 MET GLU ASP VAL ARG ARG MET ALA LEU GLY LEU VAL VAL
SEQRES 2 0 493 MET MET ALA LEU ALA LEU SER GLY VAL GLY ALA SER VAL
SEQRES 3 0 493 MET GLU ASP THR LEU LEU SER VAL LEU PHE GLU ASN TYR
SEQRES 4 0 493 ASN PRO LYS VAL ARG PRO SER GLN THR VAL GLY ASP LYS
SEQRES 5 0 493 VAL THR VAL ARG VAL GLY LEU THR LEU THR SER LEU LEU
SEQRES 6 0 493 ILE LEU ASN GLU LYS ASN GLU GLU MET THR THR SER VAL
SEQRES 7 0 493 PHE LEU ASN LEU ALA TRP THR ASP TYR ARG LEU GLN TRP
SEQRES 8 0 493 ASP PRO ALA ALA TYR GLU GLY ILE LYS ASP LEU SER ILE
SEQRES 9 0 493 PRO SER ASP ASP VAL TRP GLN PRO ASP ILE VAL LEU MET
SEQRES 10 0 493 ASN ASN ASN ASP GLY SER PHE GLU ILE THR LEU HIS VAL
SEQRES 11 0 493 ASN VAL LEU VAL GLN HIS THR GLY ALA VAL SER TRP HIS
SEQRES 12 0 493 PRO SER ALA ILE TYR ARG SER SER CYS THR ILE LYS VAL
SEQRES 13 0 493 MET TYR PHE PRO PHE ASP TRP GLN ASN CYS THR MET VAL
SEQRES 14 0 493 PHE LYS SER TYR THR TYR ASP THR SER GLU VAL ILE LEU
SEQRES 15 0 493 GLN HIS ALA LEU ASP ALA LYS GLY GLU ARG GLU VAL LYS
SEQRES 16 0 493 GLU ILE MET ILE ASN GLN ASP ALA PHE THR GLU ASN GLY
SEQRES 17 0 493 GLN TRP SER ILE GLU HIS LYS PRO SER ARG LYS ASN TRP
SEQRES 18 0 493 ARG SER ASP ASP PRO SER TYR GLU ASP VAL THR PHE TYR
SEQRES 19 0 493 LEU ILE ILE GLN ARG LYS PRO LEU PHE TYR ILE VAL TYR
SEQRES 20 0 493 THR ILE VAL PRO CYS ILE LEU ILE SER ILE LEU ALA ILE
SEQRES 21 0 493 LEU VAL PHE TYR LEU PRO PRO ASP ALA GLY GLU LYS MET
SEQRES 22 0 493 SER LEU SER ILE SER ALA LEU LEU ALA LEU THR VAL PHE
SEQRES 23 0 493 LEU LEU LEU LEU ALA ASP LYS VAL PRO GLU THR SER LEU
SEQRES 24 0 493 SER VAL PRO ILE ILE ILE SER TYR LEU MET PHE ILE MET
SEQRES 25 0 493 ILE LEU VAL ALA PHE SER VAL ILE LEU SER VAL VAL VAL
SEQRES 26 0 493 LEU ASN LEU HIS HIS ARG SER PRO ASN THR HIS THR MET
SEQRES 27 0 493 PRO ASN TRP ILE ARG GLN ILE PHE ILE GLU THR LEU PRO
SEQRES 28 0 493 PRO PHE LEU TRP ILE GLN ARG PRO VAL THR THR PRO SER
SEQRES 29 0 493 PRO ASP SER LYS PRO THR ILE ILE SER ARG ALA ASN ASP
SEQRES 30 0 493 GLU TYR PHE ILE ARG LYS PRO ALA GLY ASP PHE VAL CYS
SEQRES 31 0 493 PRO VAL ASP ASN ALA ARG VAL ALA VAL GLN PRO GLU ARG
SEQRES 32 0 493 LEU PHE SER GLU MET LYS TRP HIS LEU ASN GLY LEU THR
SEQRES 33 0 493 GLN PRO VAL THR LEU PRO GLN ASP LEU LYS GLU ALA VAL
SEQRES 34 0 493 GLU ALA ILE LYS TYR ILE ALA GLU GLN LEU GLU SER ALA
SEQRES 35 0 493 SER GLU PHE ASP ASP LEU LYS LYS ASP TRP GLN TYR VAL
SEQRES 36 0 493 ALA MET VAL ALA ASP ARG LEU PHE LEU TYR ILE PHE ILE
SEQRES 37 0 493 THR MET CYS SER ILE GLY THR PHE SER ILE PHE LEU ASP
SEQRES 38 0 493 ALA SER HIS ASN VAL PRO PRO ASP ASN PRO PHE ALA
SEQRES 1 1 522 MET GLY ASN ILE HIS PHE VAL TYR LEU LEU ILE SER CYS
SEQRES 2 1 522 LEU TYR TYR SER GLY CYS SER GLY VAL ASN GLU GLU GLU
SEQRES 3 1 522 ARG LEU ILE ASN ASP LEU LEU ILE VAL ASN LYS TYR ASN
SEQRES 4 1 522 LYS HIS VAL ARG PRO VAL LYS HIS ASN ASN GLU VAL VAL
SEQRES 5 1 522 ASN ILE ALA LEU SER LEU THR LEU SER ASN LEU ILE SER
SEQRES 6 1 522 LEU LYS GLU THR ASP GLU THR LEU THR THR ASN VAL TRP
SEQRES 7 1 522 MET ASP HIS ALA TRP TYR ASP HIS ARG LEU THR TRP ASN
SEQRES 8 1 522 ALA SER GLU TYR SER ASP ILE SER ILE LEU ARG LEU ARG
SEQRES 9 1 522 PRO GLU LEU ILE TRP ILE PRO ASP ILE VAL LEU GLN ASN
SEQRES 10 1 522 ASN ASN ASP GLY GLN TYR ASN VAL ALA TYR PHE CYS ASN
SEQRES 11 1 522 VAL LEU VAL ARG PRO ASN GLY TYR VAL THR TRP LEU PRO
SEQRES 12 1 522 PRO ALA ILE PHE ARG SER SER CYS PRO ILE ASN VAL LEU
SEQRES 13 1 522 TYR PHE PRO PHE ASP TRP GLN ASN CYS SER LEU LYS PHE
SEQRES 14 1 522 THR ALA LEU ASN TYR ASN ALA ASN GLU ILE SER MET ASP
SEQRES 15 1 522 LEU MET THR ASP THR ILE ASP GLY LYS ASP TYR PRO ILE
SEQRES 16 1 522 GLU TRP ILE ILE ILE ASP PRO GLU ALA PHE THR GLU ASN
SEQRES 17 1 522 GLY GLU TRP GLU ILE ILE HIS LYS PRO ALA LYS LYS ASN
SEQRES 18 1 522 ILE TYR GLY ASP LYS PHE PRO ASN GLY THR ASN TYR GLN
SEQRES 19 1 522 ASP VAL THR PHE TYR LEU ILE ILE ARG ARG LYS PRO LEU
SEQRES 20 1 522 PHE TYR VAL ILE ASN PHE ILE THR PRO CYS VAL LEU ILE
SEQRES 21 1 522 SER PHE LEU ALA ALA LEU ALA PHE TYR LEU PRO ALA GLU
SEQRES 22 1 522 SER GLY GLU LYS MET SER THR ALA ILE CYS VAL LEU LEU
SEQRES 23 1 522 ALA GLN ALA VAL PHE LEU LEU LEU THR SER GLN ARG LEU
SEQRES 24 1 522 PRO GLU THR ALA LEU ALA VAL PRO LEU ILE GLY LYS TYR
SEQRES 25 1 522 LEU MET PHE ILE MET SER LEU VAL THR GLY VAL VAL VAL
SEQRES 26 1 522 ASN CYS GLY ILE VAL LEU ASN PHE HIS PHE ARG THR PRO
SEQRES 27 1 522 SER THR HIS VAL LEU SER THR ARG VAL LYS GLN ILE PHE
SEQRES 28 1 522 LEU GLU LYS LEU PRO ARG ILE LEU HIS MET SER ARG VAL
SEQRES 29 1 522 ASP GLU ILE GLU GLN PRO ASP TRP GLN ASN ASP LEU LYS
SEQRES 30 1 522 LEU ARG ARG SER SER SER VAL GLY TYR ILE SER LYS ALA
SEQRES 31 1 522 GLN GLU TYR PHE ASN ILE LYS SER ARG SER GLU LEU MET
SEQRES 32 1 522 PHE GLU LYS GLN SER GLU ARG HIS GLY LEU VAL PRO ARG
SEQRES 33 1 522 VAL THR PRO ARG ILE GLY PHE GLY ASN ASN ASN GLU ASN
SEQRES 34 1 522 ILE ALA ALA SER ASP GLN LEU HIS ASP GLU ILE LYS SER
SEQRES 35 1 522 GLY ILE ASP SER THR ASN TYR ILE VAL LYS GLN ILE LYS
SEQRES 36 1 522 GLU LYS ASN ALA TYR ASP GLU GLU VAL GLY ASN TRP ASN
SEQRES 37 1 522 LEU VAL GLY GLN THR ILE ASP ARG LEU SER MET PHE ILE
SEQRES 38 1 522 ILE THR PRO VAL MET VAL LEU GLY THR ILE PHE ILE PHE
SEQRES 39 1 522 VAL MET GLY ASN PHE ASN ARG PRO PRO ALA LYS PRO PHE
SEQRES 40 1 522 GLU GLY ASP PRO PHE ASP TYR SER SER ASP HIS PRO ARG
SEQRES 41 1 522 CYS ALA
SEQRES 1 2 461 MET ILE LEU CYS SER TYR TRP HIS VAL GLY LEU VAL LEU
SEQRES 2 2 461 LEU LEU PHE SER CYS CYS GLY LEU VAL LEU GLY SER GLU
SEQRES 3 2 461 HIS GLU THR ARG LEU VAL ALA ASN LEU LEU GLU ASN TYR
SEQRES 4 2 461 ASN LYS VAL ILE ARG PRO VAL GLU HIS HIS THR HIS PHE
SEQRES 5 2 461 VAL ASP ILE THR VAL GLY LEU GLN LEU ILE GLN LEU ILE
SEQRES 6 2 461 ASN VAL ASP GLU VAL ASN GLN ILE VAL GLU THR ASN VAL
SEQRES 7 2 461 ARG LEU ARG GLN GLN TRP ILE ASP VAL ARG LEU ARG TRP
SEQRES 8 2 461 ASN PRO ALA ASP TYR GLY GLY ILE LYS LYS ILE ARG LEU
SEQRES 9 2 461 PRO SER ASP ASP VAL TRP LEU PRO ASP LEU VAL LEU TYR
SEQRES 10 2 461 ASN ASN ALA ASP GLY ASP PHE ALA ILE VAL HIS MET THR
SEQRES 11 2 461 LYS LEU LEU LEU ASP TYR THR GLY LYS ILE MET TRP THR
SEQRES 12 2 461 PRO PRO ALA ILE PHE LYS SER TYR CYS GLU ILE ILE VAL
SEQRES 13 2 461 THR HIS PHE PRO PHE ASP GLN GLN ASN CYS THR MET LYS
SEQRES 14 2 461 LEU GLY ILE TRP THR TYR ASP GLY THR LYS VAL SER ILE
SEQRES 15 2 461 SER PRO GLU SER ASP ARG PRO ASP LEU SER THR PHE MET
SEQRES 16 2 461 GLU SER GLY GLU TRP VAL MET LYS ASP TYR ARG GLY TRP
SEQRES 17 2 461 LYS HIS TRP VAL TYR TYR THR CYS CYS PRO ASP THR PRO
SEQRES 18 2 461 TYR LEU ASP ILE THR TYR HIS PHE ILE MET GLN ARG ILE
SEQRES 19 2 461 PRO LEU TYR PHE VAL VAL ASN VAL ILE ILE PRO CYS LEU
SEQRES 20 2 461 LEU PHE SER PHE LEU THR VAL LEU VAL PHE TYR LEU PRO
SEQRES 21 2 461 THR ASP SER GLY GLU LYS MET THR LEU SER ILE SER VAL
SEQRES 22 2 461 LEU LEU SER LEU THR VAL PHE LEU LEU VAL ILE VAL GLU
SEQRES 23 2 461 LEU ILE PRO SER THR SER SER ALA VAL PRO LEU ILE GLY
SEQRES 24 2 461 LYS TYR MET LEU PHE THR MET ILE PHE VAL ILE SER SER
SEQRES 25 2 461 ILE ILE VAL THR VAL VAL VAL ILE ASN THR HIS HIS ARG
SEQRES 26 2 461 SER PRO SER THR HIS THR MET PRO GLN TRP VAL ARG LYS
SEQRES 27 2 461 ILE PHE ILE ASN THR ILE PRO ASN VAL MET PHE PHE SER
SEQRES 28 2 461 THR MET LYS ARG ALA SER LYS GLU LYS GLN GLU ASN LYS
SEQRES 29 2 461 ILE PHE ALA ASP ASP ILE ASP ILE SER ASP ILE SER GLY
SEQRES 30 2 461 LYS GLN VAL THR GLY GLU VAL ILE PHE GLN THR PRO LEU
SEQRES 31 2 461 ILE LYS ASN PRO ASP VAL LYS SER ALA ILE GLU GLY VAL
SEQRES 32 2 461 LYS TYR ILE ALA GLU HIS MET LYS SER ASP GLU GLU SER
SEQRES 33 2 461 SER ASN ALA ALA GLU GLU TRP LYS TYR VAL ALA MET VAL
SEQRES 34 2 461 ILE ASP HIS ILE LEU LEU CYS VAL PHE MET LEU ILE CYS
SEQRES 35 2 461 ILE ILE GLY THR VAL SER VAL PHE ALA GLY ARG LEU ILE
SEQRES 36 2 461 GLU LEU SER GLN GLU GLY
SEQRES 1 3 505 MET VAL LEU THR LEU LEU LEU ILE ILE CYS LEU ALA LEU
SEQRES 2 3 505 GLU VAL ARG SER ASN GLU GLU GLY ARG LEU ILE GLU LYS
SEQRES 3 3 505 LEU LEU GLY ASP TYR ASP LYS ARG ILE LYS PRO ALA LYS
SEQRES 4 3 505 THR LEU ASP HIS VAL ILE ASP VAL THR LEU LYS LEU THR
SEQRES 5 3 505 LEU THR ASN LEU ILE SER LEU ASN GLU LYS GLU GLU ALA
SEQRES 6 3 505 LEU THR THR ASN VAL TRP ILE GLU ILE GLN TRP ASN ASP
SEQRES 7 3 505 TYR ARG LEU SER TRP ASN THR SER GLU TYR GLU GLY ILE
SEQRES 8 3 505 ASP LEU VAL ARG ILE PRO SER GLU LEU LEU TRP LEU PRO
SEQRES 9 3 505 ASP VAL VAL LEU GLU ASN ASN VAL ASP GLY GLN PHE GLU
SEQRES 10 3 505 VAL ALA TYR TYR ALA ASN VAL LEU VAL TYR ASN ASP GLY
SEQRES 11 3 505 SER MET TYR TRP LEU PRO PRO ALA ILE TYR ARG SER THR
SEQRES 12 3 505 CYS PRO ILE ALA VAL THR TYR PHE PRO PHE ASP TRP GLN
SEQRES 13 3 505 ASN CYS SER LEU VAL PHE ARG SER GLN THR TYR ASN ALA
SEQRES 14 3 505 HIS GLU VAL ASN LEU GLN LEU SER ALA GLU GLU GLY GLU
SEQRES 15 3 505 VAL VAL GLU TRP ILE HIS ILE ASP PRO GLU ASP PHE THR
SEQRES 16 3 505 GLU ASN GLY GLU TRP THR ILE ARG HIS ARG PRO ALA LYS
SEQRES 17 3 505 LYS ASN TYR ASN TRP GLN LEU THR LYS ASP ASP ILE ASP
SEQRES 18 3 505 PHE GLN GLU ILE ILE PHE PHE LEU ILE ILE GLN ARG LYS
SEQRES 19 3 505 PRO LEU PHE TYR ILE ILE ASN ILE ILE ALA PRO CYS VAL
SEQRES 20 3 505 LEU ILE SER SER LEU VAL VAL LEU VAL TYR PHE LEU PRO
SEQRES 21 3 505 ALA GLN ALA GLY GLY GLN LYS CYS THR LEU SER ILE SER
SEQRES 22 3 505 VAL LEU LEU ALA GLN THR ILE PHE LEU PHE LEU ILE ALA
SEQRES 23 3 505 GLN LYS VAL PRO GLU THR SER LEU ASN VAL PRO LEU ILE
SEQRES 24 3 505 GLY LYS TYR LEU ILE PHE VAL MET PHE VAL SER LEU VAL
SEQRES 25 3 505 ILE VAL THR ASN CYS VAL ILE VAL LEU ASN VAL SER LEU
SEQRES 26 3 505 ARG THR PRO ASN THR HIS SER LEU SER GLU LYS ILE LYS
SEQRES 27 3 505 HIS LEU PHE LEU GLU PHE LEU PRO LYS TYR LEU GLY MET
SEQRES 28 3 505 HIS LEU GLU PRO SER GLU GLU THR PRO GLU LYS PRO GLN
SEQRES 29 3 505 PRO ARG ARG ARG SER SER PHE GLY ILE MET ILE LYS ALA
SEQRES 30 3 505 GLU GLU TYR ILE LEU LYS LYS PRO ARG SER GLU LEU MET
SEQRES 31 3 505 PHE GLU GLU GLN LYS ASP ARG HIS GLY LEU LYS ARG VAL
SEQRES 32 3 505 ASN LYS MET THR SER ASP ILE ASP ILE GLY THR THR VAL
SEQRES 33 3 505 ASP LEU TYR LYS ASP LEU ALA ASN PHE ALA PRO GLU ILE
SEQRES 34 3 505 LYS SER CYS VAL GLU ALA CYS ASN PHE ILE ALA LYS SER
SEQRES 35 3 505 THR LYS GLU GLN ASN ASP SER GLY SER GLU ASN GLU ASN
SEQRES 36 3 505 TRP VAL LEU ILE GLY LYS VAL ILE ASP LYS ALA CYS PHE
SEQRES 37 3 505 TRP ILE ALA LEU LEU LEU PHE SER LEU GLY THR LEU ALA
SEQRES 38 3 505 ILE PHE LEU THR GLY HIS LEU ASN GLN VAL PRO GLU PHE
SEQRES 39 3 505 PRO PHE PRO GLY ASP PRO ARG LYS TYR VAL PRO
SEQRES 1 A 461 MET ILE LEU CYS SER TYR TRP HIS VAL GLY LEU VAL LEU
SEQRES 2 A 461 LEU LEU PHE SER CYS CYS GLY LEU VAL LEU GLY SER GLU
SEQRES 3 A 461 HIS GLU THR ARG LEU VAL ALA ASN LEU LEU GLU ASN TYR
SEQRES 4 A 461 ASN LYS VAL ILE ARG PRO VAL GLU HIS HIS THR HIS PHE
SEQRES 5 A 461 VAL ASP ILE THR VAL GLY LEU GLN LEU ILE GLN LEU ILE
SEQRES 6 A 461 ASN VAL ASP GLU VAL ASN GLN ILE VAL GLU THR ASN VAL
SEQRES 7 A 461 ARG LEU ARG GLN GLN TRP ILE ASP VAL ARG LEU ARG TRP
SEQRES 8 A 461 ASN PRO ALA ASP TYR GLY GLY ILE LYS LYS ILE ARG LEU
SEQRES 9 A 461 PRO SER ASP ASP VAL TRP LEU PRO ASP LEU VAL LEU TYR
SEQRES 10 A 461 ASN ASN ALA ASP GLY ASP PHE ALA ILE VAL HIS MET THR
SEQRES 11 A 461 LYS LEU LEU LEU ASP TYR THR GLY LYS ILE MET TRP THR
SEQRES 12 A 461 PRO PRO ALA ILE PHE LYS SER TYR CYS GLU ILE ILE VAL
SEQRES 13 A 461 THR HIS PHE PRO PHE ASP GLN GLN ASN CYS THR MET LYS
SEQRES 14 A 461 LEU GLY ILE TRP THR TYR ASP GLY THR LYS VAL SER ILE
SEQRES 15 A 461 SER PRO GLU SER ASP ARG PRO ASP LEU SER THR PHE MET
SEQRES 16 A 461 GLU SER GLY GLU TRP VAL MET LYS ASP TYR ARG GLY TRP
SEQRES 17 A 461 LYS HIS TRP VAL TYR TYR THR CYS CYS PRO ASP THR PRO
SEQRES 18 A 461 TYR LEU ASP ILE THR TYR HIS PHE ILE MET GLN ARG ILE
SEQRES 19 A 461 PRO LEU TYR PHE VAL VAL ASN VAL ILE ILE PRO CYS LEU
SEQRES 20 A 461 LEU PHE SER PHE LEU THR VAL LEU VAL PHE TYR LEU PRO
SEQRES 21 A 461 THR ASP SER GLY GLU LYS MET THR LEU SER ILE SER VAL
SEQRES 22 A 461 LEU LEU SER LEU THR VAL PHE LEU LEU VAL ILE VAL GLU
SEQRES 23 A 461 LEU ILE PRO SER THR SER SER ALA VAL PRO LEU ILE GLY
SEQRES 24 A 461 LYS TYR MET LEU PHE THR MET ILE PHE VAL ILE SER SER
SEQRES 25 A 461 ILE ILE VAL THR VAL VAL VAL ILE ASN THR HIS HIS ARG
SEQRES 26 A 461 SER PRO SER THR HIS THR MET PRO GLN TRP VAL ARG LYS
SEQRES 27 A 461 ILE PHE ILE ASN THR ILE PRO ASN VAL MET PHE PHE SER
SEQRES 28 A 461 THR MET LYS ARG ALA SER LYS GLU LYS GLN GLU ASN LYS
SEQRES 29 A 461 ILE PHE ALA ASP ASP ILE ASP ILE SER ASP ILE SER GLY
SEQRES 30 A 461 LYS GLN VAL THR GLY GLU VAL ILE PHE GLN THR PRO LEU
SEQRES 31 A 461 ILE LYS ASN PRO ASP VAL LYS SER ALA ILE GLU GLY VAL
SEQRES 32 A 461 LYS TYR ILE ALA GLU HIS MET LYS SER ASP GLU GLU SER
SEQRES 33 A 461 SER ASN ALA ALA GLU GLU TRP LYS TYR VAL ALA MET VAL
SEQRES 34 A 461 ILE ASP HIS ILE LEU LEU CYS VAL PHE MET LEU ILE CYS
SEQRES 35 A 461 ILE ILE GLY THR VAL SER VAL PHE ALA GLY ARG LEU ILE
SEQRES 36 A 461 GLU LEU SER GLN GLU GLY
SEQRES 1 B 493 MET GLU ASP VAL ARG ARG MET ALA LEU GLY LEU VAL VAL
SEQRES 2 B 493 MET MET ALA LEU ALA LEU SER GLY VAL GLY ALA SER VAL
SEQRES 3 B 493 MET GLU ASP THR LEU LEU SER VAL LEU PHE GLU ASN TYR
SEQRES 4 B 493 ASN PRO LYS VAL ARG PRO SER GLN THR VAL GLY ASP LYS
SEQRES 5 B 493 VAL THR VAL ARG VAL GLY LEU THR LEU THR SER LEU LEU
SEQRES 6 B 493 ILE LEU ASN GLU LYS ASN GLU GLU MET THR THR SER VAL
SEQRES 7 B 493 PHE LEU ASN LEU ALA TRP THR ASP TYR ARG LEU GLN TRP
SEQRES 8 B 493 ASP PRO ALA ALA TYR GLU GLY ILE LYS ASP LEU SER ILE
SEQRES 9 B 493 PRO SER ASP ASP VAL TRP GLN PRO ASP ILE VAL LEU MET
SEQRES 10 B 493 ASN ASN ASN ASP GLY SER PHE GLU ILE THR LEU HIS VAL
SEQRES 11 B 493 ASN VAL LEU VAL GLN HIS THR GLY ALA VAL SER TRP HIS
SEQRES 12 B 493 PRO SER ALA ILE TYR ARG SER SER CYS THR ILE LYS VAL
SEQRES 13 B 493 MET TYR PHE PRO PHE ASP TRP GLN ASN CYS THR MET VAL
SEQRES 14 B 493 PHE LYS SER TYR THR TYR ASP THR SER GLU VAL ILE LEU
SEQRES 15 B 493 GLN HIS ALA LEU ASP ALA LYS GLY GLU ARG GLU VAL LYS
SEQRES 16 B 493 GLU ILE MET ILE ASN GLN ASP ALA PHE THR GLU ASN GLY
SEQRES 17 B 493 GLN TRP SER ILE GLU HIS LYS PRO SER ARG LYS ASN TRP
SEQRES 18 B 493 ARG SER ASP ASP PRO SER TYR GLU ASP VAL THR PHE TYR
SEQRES 19 B 493 LEU ILE ILE GLN ARG LYS PRO LEU PHE TYR ILE VAL TYR
SEQRES 20 B 493 THR ILE VAL PRO CYS ILE LEU ILE SER ILE LEU ALA ILE
SEQRES 21 B 493 LEU VAL PHE TYR LEU PRO PRO ASP ALA GLY GLU LYS MET
SEQRES 22 B 493 SER LEU SER ILE SER ALA LEU LEU ALA LEU THR VAL PHE
SEQRES 23 B 493 LEU LEU LEU LEU ALA ASP LYS VAL PRO GLU THR SER LEU
SEQRES 24 B 493 SER VAL PRO ILE ILE ILE SER TYR LEU MET PHE ILE MET
SEQRES 25 B 493 ILE LEU VAL ALA PHE SER VAL ILE LEU SER VAL VAL VAL
SEQRES 26 B 493 LEU ASN LEU HIS HIS ARG SER PRO ASN THR HIS THR MET
SEQRES 27 B 493 PRO ASN TRP ILE ARG GLN ILE PHE ILE GLU THR LEU PRO
SEQRES 28 B 493 PRO PHE LEU TRP ILE GLN ARG PRO VAL THR THR PRO SER
SEQRES 29 B 493 PRO ASP SER LYS PRO THR ILE ILE SER ARG ALA ASN ASP
SEQRES 30 B 493 GLU TYR PHE ILE ARG LYS PRO ALA GLY ASP PHE VAL CYS
SEQRES 31 B 493 PRO VAL ASP ASN ALA ARG VAL ALA VAL GLN PRO GLU ARG
SEQRES 32 B 493 LEU PHE SER GLU MET LYS TRP HIS LEU ASN GLY LEU THR
SEQRES 33 B 493 GLN PRO VAL THR LEU PRO GLN ASP LEU LYS GLU ALA VAL
SEQRES 34 B 493 GLU ALA ILE LYS TYR ILE ALA GLU GLN LEU GLU SER ALA
SEQRES 35 B 493 SER GLU PHE ASP ASP LEU LYS LYS ASP TRP GLN TYR VAL
SEQRES 36 B 493 ALA MET VAL ALA ASP ARG LEU PHE LEU TYR ILE PHE ILE
SEQRES 37 B 493 THR MET CYS SER ILE GLY THR PHE SER ILE PHE LEU ASP
SEQRES 38 B 493 ALA SER HIS ASN VAL PRO PRO ASP ASN PRO PHE ALA
SEQRES 1 C 522 MET GLY ASN ILE HIS PHE VAL TYR LEU LEU ILE SER CYS
SEQRES 2 C 522 LEU TYR TYR SER GLY CYS SER GLY VAL ASN GLU GLU GLU
SEQRES 3 C 522 ARG LEU ILE ASN ASP LEU LEU ILE VAL ASN LYS TYR ASN
SEQRES 4 C 522 LYS HIS VAL ARG PRO VAL LYS HIS ASN ASN GLU VAL VAL
SEQRES 5 C 522 ASN ILE ALA LEU SER LEU THR LEU SER ASN LEU ILE SER
SEQRES 6 C 522 LEU LYS GLU THR ASP GLU THR LEU THR THR ASN VAL TRP
SEQRES 7 C 522 MET ASP HIS ALA TRP TYR ASP HIS ARG LEU THR TRP ASN
SEQRES 8 C 522 ALA SER GLU TYR SER ASP ILE SER ILE LEU ARG LEU ARG
SEQRES 9 C 522 PRO GLU LEU ILE TRP ILE PRO ASP ILE VAL LEU GLN ASN
SEQRES 10 C 522 ASN ASN ASP GLY GLN TYR ASN VAL ALA TYR PHE CYS ASN
SEQRES 11 C 522 VAL LEU VAL ARG PRO ASN GLY TYR VAL THR TRP LEU PRO
SEQRES 12 C 522 PRO ALA ILE PHE ARG SER SER CYS PRO ILE ASN VAL LEU
SEQRES 13 C 522 TYR PHE PRO PHE ASP TRP GLN ASN CYS SER LEU LYS PHE
SEQRES 14 C 522 THR ALA LEU ASN TYR ASN ALA ASN GLU ILE SER MET ASP
SEQRES 15 C 522 LEU MET THR ASP THR ILE ASP GLY LYS ASP TYR PRO ILE
SEQRES 16 C 522 GLU TRP ILE ILE ILE ASP PRO GLU ALA PHE THR GLU ASN
SEQRES 17 C 522 GLY GLU TRP GLU ILE ILE HIS LYS PRO ALA LYS LYS ASN
SEQRES 18 C 522 ILE TYR GLY ASP LYS PHE PRO ASN GLY THR ASN TYR GLN
SEQRES 19 C 522 ASP VAL THR PHE TYR LEU ILE ILE ARG ARG LYS PRO LEU
SEQRES 20 C 522 PHE TYR VAL ILE ASN PHE ILE THR PRO CYS VAL LEU ILE
SEQRES 21 C 522 SER PHE LEU ALA ALA LEU ALA PHE TYR LEU PRO ALA GLU
SEQRES 22 C 522 SER GLY GLU LYS MET SER THR ALA ILE CYS VAL LEU LEU
SEQRES 23 C 522 ALA GLN ALA VAL PHE LEU LEU LEU THR SER GLN ARG LEU
SEQRES 24 C 522 PRO GLU THR ALA LEU ALA VAL PRO LEU ILE GLY LYS TYR
SEQRES 25 C 522 LEU MET PHE ILE MET SER LEU VAL THR GLY VAL VAL VAL
SEQRES 26 C 522 ASN CYS GLY ILE VAL LEU ASN PHE HIS PHE ARG THR PRO
SEQRES 27 C 522 SER THR HIS VAL LEU SER THR ARG VAL LYS GLN ILE PHE
SEQRES 28 C 522 LEU GLU LYS LEU PRO ARG ILE LEU HIS MET SER ARG VAL
SEQRES 29 C 522 ASP GLU ILE GLU GLN PRO ASP TRP GLN ASN ASP LEU LYS
SEQRES 30 C 522 LEU ARG ARG SER SER SER VAL GLY TYR ILE SER LYS ALA
SEQRES 31 C 522 GLN GLU TYR PHE ASN ILE LYS SER ARG SER GLU LEU MET
SEQRES 32 C 522 PHE GLU LYS GLN SER GLU ARG HIS GLY LEU VAL PRO ARG
SEQRES 33 C 522 VAL THR PRO ARG ILE GLY PHE GLY ASN ASN ASN GLU ASN
SEQRES 34 C 522 ILE ALA ALA SER ASP GLN LEU HIS ASP GLU ILE LYS SER
SEQRES 35 C 522 GLY ILE ASP SER THR ASN TYR ILE VAL LYS GLN ILE LYS
SEQRES 36 C 522 GLU LYS ASN ALA TYR ASP GLU GLU VAL GLY ASN TRP ASN
SEQRES 37 C 522 LEU VAL GLY GLN THR ILE ASP ARG LEU SER MET PHE ILE
SEQRES 38 C 522 ILE THR PRO VAL MET VAL LEU GLY THR ILE PHE ILE PHE
SEQRES 39 C 522 VAL MET GLY ASN PHE ASN ARG PRO PRO ALA LYS PRO PHE
SEQRES 40 C 522 GLU GLY ASP PRO PHE ASP TYR SER SER ASP HIS PRO ARG
SEQRES 41 C 522 CYS ALA
SEQRES 1 D 461 MET ILE LEU CYS SER TYR TRP HIS VAL GLY LEU VAL LEU
SEQRES 2 D 461 LEU LEU PHE SER CYS CYS GLY LEU VAL LEU GLY SER GLU
SEQRES 3 D 461 HIS GLU THR ARG LEU VAL ALA ASN LEU LEU GLU ASN TYR
SEQRES 4 D 461 ASN LYS VAL ILE ARG PRO VAL GLU HIS HIS THR HIS PHE
SEQRES 5 D 461 VAL ASP ILE THR VAL GLY LEU GLN LEU ILE GLN LEU ILE
SEQRES 6 D 461 ASN VAL ASP GLU VAL ASN GLN ILE VAL GLU THR ASN VAL
SEQRES 7 D 461 ARG LEU ARG GLN GLN TRP ILE ASP VAL ARG LEU ARG TRP
SEQRES 8 D 461 ASN PRO ALA ASP TYR GLY GLY ILE LYS LYS ILE ARG LEU
SEQRES 9 D 461 PRO SER ASP ASP VAL TRP LEU PRO ASP LEU VAL LEU TYR
SEQRES 10 D 461 ASN ASN ALA ASP GLY ASP PHE ALA ILE VAL HIS MET THR
SEQRES 11 D 461 LYS LEU LEU LEU ASP TYR THR GLY LYS ILE MET TRP THR
SEQRES 12 D 461 PRO PRO ALA ILE PHE LYS SER TYR CYS GLU ILE ILE VAL
SEQRES 13 D 461 THR HIS PHE PRO PHE ASP GLN GLN ASN CYS THR MET LYS
SEQRES 14 D 461 LEU GLY ILE TRP THR TYR ASP GLY THR LYS VAL SER ILE
SEQRES 15 D 461 SER PRO GLU SER ASP ARG PRO ASP LEU SER THR PHE MET
SEQRES 16 D 461 GLU SER GLY GLU TRP VAL MET LYS ASP TYR ARG GLY TRP
SEQRES 17 D 461 LYS HIS TRP VAL TYR TYR THR CYS CYS PRO ASP THR PRO
SEQRES 18 D 461 TYR LEU ASP ILE THR TYR HIS PHE ILE MET GLN ARG ILE
SEQRES 19 D 461 PRO LEU TYR PHE VAL VAL ASN VAL ILE ILE PRO CYS LEU
SEQRES 20 D 461 LEU PHE SER PHE LEU THR VAL LEU VAL PHE TYR LEU PRO
SEQRES 21 D 461 THR ASP SER GLY GLU LYS MET THR LEU SER ILE SER VAL
SEQRES 22 D 461 LEU LEU SER LEU THR VAL PHE LEU LEU VAL ILE VAL GLU
SEQRES 23 D 461 LEU ILE PRO SER THR SER SER ALA VAL PRO LEU ILE GLY
SEQRES 24 D 461 LYS TYR MET LEU PHE THR MET ILE PHE VAL ILE SER SER
SEQRES 25 D 461 ILE ILE VAL THR VAL VAL VAL ILE ASN THR HIS HIS ARG
SEQRES 26 D 461 SER PRO SER THR HIS THR MET PRO GLN TRP VAL ARG LYS
SEQRES 27 D 461 ILE PHE ILE ASN THR ILE PRO ASN VAL MET PHE PHE SER
SEQRES 28 D 461 THR MET LYS ARG ALA SER LYS GLU LYS GLN GLU ASN LYS
SEQRES 29 D 461 ILE PHE ALA ASP ASP ILE ASP ILE SER ASP ILE SER GLY
SEQRES 30 D 461 LYS GLN VAL THR GLY GLU VAL ILE PHE GLN THR PRO LEU
SEQRES 31 D 461 ILE LYS ASN PRO ASP VAL LYS SER ALA ILE GLU GLY VAL
SEQRES 32 D 461 LYS TYR ILE ALA GLU HIS MET LYS SER ASP GLU GLU SER
SEQRES 33 D 461 SER ASN ALA ALA GLU GLU TRP LYS TYR VAL ALA MET VAL
SEQRES 34 D 461 ILE ASP HIS ILE LEU LEU CYS VAL PHE MET LEU ILE CYS
SEQRES 35 D 461 ILE ILE GLY THR VAL SER VAL PHE ALA GLY ARG LEU ILE
SEQRES 36 D 461 GLU LEU SER GLN GLU GLY
SEQRES 1 E 505 MET VAL LEU THR LEU LEU LEU ILE ILE CYS LEU ALA LEU
SEQRES 2 E 505 GLU VAL ARG SER ASN GLU GLU GLY ARG LEU ILE GLU LYS
SEQRES 3 E 505 LEU LEU GLY ASP TYR ASP LYS ARG ILE LYS PRO ALA LYS
SEQRES 4 E 505 THR LEU ASP HIS VAL ILE ASP VAL THR LEU LYS LEU THR
SEQRES 5 E 505 LEU THR ASN LEU ILE SER LEU ASN GLU LYS GLU GLU ALA
SEQRES 6 E 505 LEU THR THR ASN VAL TRP ILE GLU ILE GLN TRP ASN ASP
SEQRES 7 E 505 TYR ARG LEU SER TRP ASN THR SER GLU TYR GLU GLY ILE
SEQRES 8 E 505 ASP LEU VAL ARG ILE PRO SER GLU LEU LEU TRP LEU PRO
SEQRES 9 E 505 ASP VAL VAL LEU GLU ASN ASN VAL ASP GLY GLN PHE GLU
SEQRES 10 E 505 VAL ALA TYR TYR ALA ASN VAL LEU VAL TYR ASN ASP GLY
SEQRES 11 E 505 SER MET TYR TRP LEU PRO PRO ALA ILE TYR ARG SER THR
SEQRES 12 E 505 CYS PRO ILE ALA VAL THR TYR PHE PRO PHE ASP TRP GLN
SEQRES 13 E 505 ASN CYS SER LEU VAL PHE ARG SER GLN THR TYR ASN ALA
SEQRES 14 E 505 HIS GLU VAL ASN LEU GLN LEU SER ALA GLU GLU GLY GLU
SEQRES 15 E 505 VAL VAL GLU TRP ILE HIS ILE ASP PRO GLU ASP PHE THR
SEQRES 16 E 505 GLU ASN GLY GLU TRP THR ILE ARG HIS ARG PRO ALA LYS
SEQRES 17 E 505 LYS ASN TYR ASN TRP GLN LEU THR LYS ASP ASP ILE ASP
SEQRES 18 E 505 PHE GLN GLU ILE ILE PHE PHE LEU ILE ILE GLN ARG LYS
SEQRES 19 E 505 PRO LEU PHE TYR ILE ILE ASN ILE ILE ALA PRO CYS VAL
SEQRES 20 E 505 LEU ILE SER SER LEU VAL VAL LEU VAL TYR PHE LEU PRO
SEQRES 21 E 505 ALA GLN ALA GLY GLY GLN LYS CYS THR LEU SER ILE SER
SEQRES 22 E 505 VAL LEU LEU ALA GLN THR ILE PHE LEU PHE LEU ILE ALA
SEQRES 23 E 505 GLN LYS VAL PRO GLU THR SER LEU ASN VAL PRO LEU ILE
SEQRES 24 E 505 GLY LYS TYR LEU ILE PHE VAL MET PHE VAL SER LEU VAL
SEQRES 25 E 505 ILE VAL THR ASN CYS VAL ILE VAL LEU ASN VAL SER LEU
SEQRES 26 E 505 ARG THR PRO ASN THR HIS SER LEU SER GLU LYS ILE LYS
SEQRES 27 E 505 HIS LEU PHE LEU GLU PHE LEU PRO LYS TYR LEU GLY MET
SEQRES 28 E 505 HIS LEU GLU PRO SER GLU GLU THR PRO GLU LYS PRO GLN
SEQRES 29 E 505 PRO ARG ARG ARG SER SER PHE GLY ILE MET ILE LYS ALA
SEQRES 30 E 505 GLU GLU TYR ILE LEU LYS LYS PRO ARG SER GLU LEU MET
SEQRES 31 E 505 PHE GLU GLU GLN LYS ASP ARG HIS GLY LEU LYS ARG VAL
SEQRES 32 E 505 ASN LYS MET THR SER ASP ILE ASP ILE GLY THR THR VAL
SEQRES 33 E 505 ASP LEU TYR LYS ASP LEU ALA ASN PHE ALA PRO GLU ILE
SEQRES 34 E 505 LYS SER CYS VAL GLU ALA CYS ASN PHE ILE ALA LYS SER
SEQRES 35 E 505 THR LYS GLU GLN ASN ASP SER GLY SER GLU ASN GLU ASN
SEQRES 36 E 505 TRP VAL LEU ILE GLY LYS VAL ILE ASP LYS ALA CYS PHE
SEQRES 37 E 505 TRP ILE ALA LEU LEU LEU PHE SER LEU GLY THR LEU ALA
SEQRES 38 E 505 ILE PHE LEU THR GLY HIS LEU ASN GLN VAL PRO GLU PHE
SEQRES 39 E 505 PRO PHE PRO GLY ASP PRO ARG LYS TYR VAL PRO
SEQRES 1 F 461 MET ILE LEU CYS SER TYR TRP HIS VAL GLY LEU VAL LEU
SEQRES 2 F 461 LEU LEU PHE SER CYS CYS GLY LEU VAL LEU GLY SER GLU
SEQRES 3 F 461 HIS GLU THR ARG LEU VAL ALA ASN LEU LEU GLU ASN TYR
SEQRES 4 F 461 ASN LYS VAL ILE ARG PRO VAL GLU HIS HIS THR HIS PHE
SEQRES 5 F 461 VAL ASP ILE THR VAL GLY LEU GLN LEU ILE GLN LEU ILE
SEQRES 6 F 461 ASN VAL ASP GLU VAL ASN GLN ILE VAL GLU THR ASN VAL
SEQRES 7 F 461 ARG LEU ARG GLN GLN TRP ILE ASP VAL ARG LEU ARG TRP
SEQRES 8 F 461 ASN PRO ALA ASP TYR GLY GLY ILE LYS LYS ILE ARG LEU
SEQRES 9 F 461 PRO SER ASP ASP VAL TRP LEU PRO ASP LEU VAL LEU TYR
SEQRES 10 F 461 ASN ASN ALA ASP GLY ASP PHE ALA ILE VAL HIS MET THR
SEQRES 11 F 461 LYS LEU LEU LEU ASP TYR THR GLY LYS ILE MET TRP THR
SEQRES 12 F 461 PRO PRO ALA ILE PHE LYS SER TYR CYS GLU ILE ILE VAL
SEQRES 13 F 461 THR HIS PHE PRO PHE ASP GLN GLN ASN CYS THR MET LYS
SEQRES 14 F 461 LEU GLY ILE TRP THR TYR ASP GLY THR LYS VAL SER ILE
SEQRES 15 F 461 SER PRO GLU SER ASP ARG PRO ASP LEU SER THR PHE MET
SEQRES 16 F 461 GLU SER GLY GLU TRP VAL MET LYS ASP TYR ARG GLY TRP
SEQRES 17 F 461 LYS HIS TRP VAL TYR TYR THR CYS CYS PRO ASP THR PRO
SEQRES 18 F 461 TYR LEU ASP ILE THR TYR HIS PHE ILE MET GLN ARG ILE
SEQRES 19 F 461 PRO LEU TYR PHE VAL VAL ASN VAL ILE ILE PRO CYS LEU
SEQRES 20 F 461 LEU PHE SER PHE LEU THR VAL LEU VAL PHE TYR LEU PRO
SEQRES 21 F 461 THR ASP SER GLY GLU LYS MET THR LEU SER ILE SER VAL
SEQRES 22 F 461 LEU LEU SER LEU THR VAL PHE LEU LEU VAL ILE VAL GLU
SEQRES 23 F 461 LEU ILE PRO SER THR SER SER ALA VAL PRO LEU ILE GLY
SEQRES 24 F 461 LYS TYR MET LEU PHE THR MET ILE PHE VAL ILE SER SER
SEQRES 25 F 461 ILE ILE VAL THR VAL VAL VAL ILE ASN THR HIS HIS ARG
SEQRES 26 F 461 SER PRO SER THR HIS THR MET PRO GLN TRP VAL ARG LYS
SEQRES 27 F 461 ILE PHE ILE ASN THR ILE PRO ASN VAL MET PHE PHE SER
SEQRES 28 F 461 THR MET LYS ARG ALA SER LYS GLU LYS GLN GLU ASN LYS
SEQRES 29 F 461 ILE PHE ALA ASP ASP ILE ASP ILE SER ASP ILE SER GLY
SEQRES 30 F 461 LYS GLN VAL THR GLY GLU VAL ILE PHE GLN THR PRO LEU
SEQRES 31 F 461 ILE LYS ASN PRO ASP VAL LYS SER ALA ILE GLU GLY VAL
SEQRES 32 F 461 LYS TYR ILE ALA GLU HIS MET LYS SER ASP GLU GLU SER
SEQRES 33 F 461 SER ASN ALA ALA GLU GLU TRP LYS TYR VAL ALA MET VAL
SEQRES 34 F 461 ILE ASP HIS ILE LEU LEU CYS VAL PHE MET LEU ILE CYS
SEQRES 35 F 461 ILE ILE GLY THR VAL SER VAL PHE ALA GLY ARG LEU ILE
SEQRES 36 F 461 GLU LEU SER GLN GLU GLY
SEQRES 1 G 493 MET GLU ASP VAL ARG ARG MET ALA LEU GLY LEU VAL VAL
SEQRES 2 G 493 MET MET ALA LEU ALA LEU SER GLY VAL GLY ALA SER VAL
SEQRES 3 G 493 MET GLU ASP THR LEU LEU SER VAL LEU PHE GLU ASN TYR
SEQRES 4 G 493 ASN PRO LYS VAL ARG PRO SER GLN THR VAL GLY ASP LYS
SEQRES 5 G 493 VAL THR VAL ARG VAL GLY LEU THR LEU THR SER LEU LEU
SEQRES 6 G 493 ILE LEU ASN GLU LYS ASN GLU GLU MET THR THR SER VAL
SEQRES 7 G 493 PHE LEU ASN LEU ALA TRP THR ASP TYR ARG LEU GLN TRP
SEQRES 8 G 493 ASP PRO ALA ALA TYR GLU GLY ILE LYS ASP LEU SER ILE
SEQRES 9 G 493 PRO SER ASP ASP VAL TRP GLN PRO ASP ILE VAL LEU MET
SEQRES 10 G 493 ASN ASN ASN ASP GLY SER PHE GLU ILE THR LEU HIS VAL
SEQRES 11 G 493 ASN VAL LEU VAL GLN HIS THR GLY ALA VAL SER TRP HIS
SEQRES 12 G 493 PRO SER ALA ILE TYR ARG SER SER CYS THR ILE LYS VAL
SEQRES 13 G 493 MET TYR PHE PRO PHE ASP TRP GLN ASN CYS THR MET VAL
SEQRES 14 G 493 PHE LYS SER TYR THR TYR ASP THR SER GLU VAL ILE LEU
SEQRES 15 G 493 GLN HIS ALA LEU ASP ALA LYS GLY GLU ARG GLU VAL LYS
SEQRES 16 G 493 GLU ILE MET ILE ASN GLN ASP ALA PHE THR GLU ASN GLY
SEQRES 17 G 493 GLN TRP SER ILE GLU HIS LYS PRO SER ARG LYS ASN TRP
SEQRES 18 G 493 ARG SER ASP ASP PRO SER TYR GLU ASP VAL THR PHE TYR
SEQRES 19 G 493 LEU ILE ILE GLN ARG LYS PRO LEU PHE TYR ILE VAL TYR
SEQRES 20 G 493 THR ILE VAL PRO CYS ILE LEU ILE SER ILE LEU ALA ILE
SEQRES 21 G 493 LEU VAL PHE TYR LEU PRO PRO ASP ALA GLY GLU LYS MET
SEQRES 22 G 493 SER LEU SER ILE SER ALA LEU LEU ALA LEU THR VAL PHE
SEQRES 23 G 493 LEU LEU LEU LEU ALA ASP LYS VAL PRO GLU THR SER LEU
SEQRES 24 G 493 SER VAL PRO ILE ILE ILE SER TYR LEU MET PHE ILE MET
SEQRES 25 G 493 ILE LEU VAL ALA PHE SER VAL ILE LEU SER VAL VAL VAL
SEQRES 26 G 493 LEU ASN LEU HIS HIS ARG SER PRO ASN THR HIS THR MET
SEQRES 27 G 493 PRO ASN TRP ILE ARG GLN ILE PHE ILE GLU THR LEU PRO
SEQRES 28 G 493 PRO PHE LEU TRP ILE GLN ARG PRO VAL THR THR PRO SER
SEQRES 29 G 493 PRO ASP SER LYS PRO THR ILE ILE SER ARG ALA ASN ASP
SEQRES 30 G 493 GLU TYR PHE ILE ARG LYS PRO ALA GLY ASP PHE VAL CYS
SEQRES 31 G 493 PRO VAL ASP ASN ALA ARG VAL ALA VAL GLN PRO GLU ARG
SEQRES 32 G 493 LEU PHE SER GLU MET LYS TRP HIS LEU ASN GLY LEU THR
SEQRES 33 G 493 GLN PRO VAL THR LEU PRO GLN ASP LEU LYS GLU ALA VAL
SEQRES 34 G 493 GLU ALA ILE LYS TYR ILE ALA GLU GLN LEU GLU SER ALA
SEQRES 35 G 493 SER GLU PHE ASP ASP LEU LYS LYS ASP TRP GLN TYR VAL
SEQRES 36 G 493 ALA MET VAL ALA ASP ARG LEU PHE LEU TYR ILE PHE ILE
SEQRES 37 G 493 THR MET CYS SER ILE GLY THR PHE SER ILE PHE LEU ASP
SEQRES 38 G 493 ALA SER HIS ASN VAL PRO PRO ASP ASN PRO PHE ALA
SEQRES 1 H 522 MET GLY ASN ILE HIS PHE VAL TYR LEU LEU ILE SER CYS
SEQRES 2 H 522 LEU TYR TYR SER GLY CYS SER GLY VAL ASN GLU GLU GLU
SEQRES 3 H 522 ARG LEU ILE ASN ASP LEU LEU ILE VAL ASN LYS TYR ASN
SEQRES 4 H 522 LYS HIS VAL ARG PRO VAL LYS HIS ASN ASN GLU VAL VAL
SEQRES 5 H 522 ASN ILE ALA LEU SER LEU THR LEU SER ASN LEU ILE SER
SEQRES 6 H 522 LEU LYS GLU THR ASP GLU THR LEU THR THR ASN VAL TRP
SEQRES 7 H 522 MET ASP HIS ALA TRP TYR ASP HIS ARG LEU THR TRP ASN
SEQRES 8 H 522 ALA SER GLU TYR SER ASP ILE SER ILE LEU ARG LEU ARG
SEQRES 9 H 522 PRO GLU LEU ILE TRP ILE PRO ASP ILE VAL LEU GLN ASN
SEQRES 10 H 522 ASN ASN ASP GLY GLN TYR ASN VAL ALA TYR PHE CYS ASN
SEQRES 11 H 522 VAL LEU VAL ARG PRO ASN GLY TYR VAL THR TRP LEU PRO
SEQRES 12 H 522 PRO ALA ILE PHE ARG SER SER CYS PRO ILE ASN VAL LEU
SEQRES 13 H 522 TYR PHE PRO PHE ASP TRP GLN ASN CYS SER LEU LYS PHE
SEQRES 14 H 522 THR ALA LEU ASN TYR ASN ALA ASN GLU ILE SER MET ASP
SEQRES 15 H 522 LEU MET THR ASP THR ILE ASP GLY LYS ASP TYR PRO ILE
SEQRES 16 H 522 GLU TRP ILE ILE ILE ASP PRO GLU ALA PHE THR GLU ASN
SEQRES 17 H 522 GLY GLU TRP GLU ILE ILE HIS LYS PRO ALA LYS LYS ASN
SEQRES 18 H 522 ILE TYR GLY ASP LYS PHE PRO ASN GLY THR ASN TYR GLN
SEQRES 19 H 522 ASP VAL THR PHE TYR LEU ILE ILE ARG ARG LYS PRO LEU
SEQRES 20 H 522 PHE TYR VAL ILE ASN PHE ILE THR PRO CYS VAL LEU ILE
SEQRES 21 H 522 SER PHE LEU ALA ALA LEU ALA PHE TYR LEU PRO ALA GLU
SEQRES 22 H 522 SER GLY GLU LYS MET SER THR ALA ILE CYS VAL LEU LEU
SEQRES 23 H 522 ALA GLN ALA VAL PHE LEU LEU LEU THR SER GLN ARG LEU
SEQRES 24 H 522 PRO GLU THR ALA LEU ALA VAL PRO LEU ILE GLY LYS TYR
SEQRES 25 H 522 LEU MET PHE ILE MET SER LEU VAL THR GLY VAL VAL VAL
SEQRES 26 H 522 ASN CYS GLY ILE VAL LEU ASN PHE HIS PHE ARG THR PRO
SEQRES 27 H 522 SER THR HIS VAL LEU SER THR ARG VAL LYS GLN ILE PHE
SEQRES 28 H 522 LEU GLU LYS LEU PRO ARG ILE LEU HIS MET SER ARG VAL
SEQRES 29 H 522 ASP GLU ILE GLU GLN PRO ASP TRP GLN ASN ASP LEU LYS
SEQRES 30 H 522 LEU ARG ARG SER SER SER VAL GLY TYR ILE SER LYS ALA
SEQRES 31 H 522 GLN GLU TYR PHE ASN ILE LYS SER ARG SER GLU LEU MET
SEQRES 32 H 522 PHE GLU LYS GLN SER GLU ARG HIS GLY LEU VAL PRO ARG
SEQRES 33 H 522 VAL THR PRO ARG ILE GLY PHE GLY ASN ASN ASN GLU ASN
SEQRES 34 H 522 ILE ALA ALA SER ASP GLN LEU HIS ASP GLU ILE LYS SER
SEQRES 35 H 522 GLY ILE ASP SER THR ASN TYR ILE VAL LYS GLN ILE LYS
SEQRES 36 H 522 GLU LYS ASN ALA TYR ASP GLU GLU VAL GLY ASN TRP ASN
SEQRES 37 H 522 LEU VAL GLY GLN THR ILE ASP ARG LEU SER MET PHE ILE
SEQRES 38 H 522 ILE THR PRO VAL MET VAL LEU GLY THR ILE PHE ILE PHE
SEQRES 39 H 522 VAL MET GLY ASN PHE ASN ARG PRO PRO ALA LYS PRO PHE
SEQRES 40 H 522 GLU GLY ASP PRO PHE ASP TYR SER SER ASP HIS PRO ARG
SEQRES 41 H 522 CYS ALA
SEQRES 1 I 461 MET ILE LEU CYS SER TYR TRP HIS VAL GLY LEU VAL LEU
SEQRES 2 I 461 LEU LEU PHE SER CYS CYS GLY LEU VAL LEU GLY SER GLU
SEQRES 3 I 461 HIS GLU THR ARG LEU VAL ALA ASN LEU LEU GLU ASN TYR
SEQRES 4 I 461 ASN LYS VAL ILE ARG PRO VAL GLU HIS HIS THR HIS PHE
SEQRES 5 I 461 VAL ASP ILE THR VAL GLY LEU GLN LEU ILE GLN LEU ILE
SEQRES 6 I 461 ASN VAL ASP GLU VAL ASN GLN ILE VAL GLU THR ASN VAL
SEQRES 7 I 461 ARG LEU ARG GLN GLN TRP ILE ASP VAL ARG LEU ARG TRP
SEQRES 8 I 461 ASN PRO ALA ASP TYR GLY GLY ILE LYS LYS ILE ARG LEU
SEQRES 9 I 461 PRO SER ASP ASP VAL TRP LEU PRO ASP LEU VAL LEU TYR
SEQRES 10 I 461 ASN ASN ALA ASP GLY ASP PHE ALA ILE VAL HIS MET THR
SEQRES 11 I 461 LYS LEU LEU LEU ASP TYR THR GLY LYS ILE MET TRP THR
SEQRES 12 I 461 PRO PRO ALA ILE PHE LYS SER TYR CYS GLU ILE ILE VAL
SEQRES 13 I 461 THR HIS PHE PRO PHE ASP GLN GLN ASN CYS THR MET LYS
SEQRES 14 I 461 LEU GLY ILE TRP THR TYR ASP GLY THR LYS VAL SER ILE
SEQRES 15 I 461 SER PRO GLU SER ASP ARG PRO ASP LEU SER THR PHE MET
SEQRES 16 I 461 GLU SER GLY GLU TRP VAL MET LYS ASP TYR ARG GLY TRP
SEQRES 17 I 461 LYS HIS TRP VAL TYR TYR THR CYS CYS PRO ASP THR PRO
SEQRES 18 I 461 TYR LEU ASP ILE THR TYR HIS PHE ILE MET GLN ARG ILE
SEQRES 19 I 461 PRO LEU TYR PHE VAL VAL ASN VAL ILE ILE PRO CYS LEU
SEQRES 20 I 461 LEU PHE SER PHE LEU THR VAL LEU VAL PHE TYR LEU PRO
SEQRES 21 I 461 THR ASP SER GLY GLU LYS MET THR LEU SER ILE SER VAL
SEQRES 22 I 461 LEU LEU SER LEU THR VAL PHE LEU LEU VAL ILE VAL GLU
SEQRES 23 I 461 LEU ILE PRO SER THR SER SER ALA VAL PRO LEU ILE GLY
SEQRES 24 I 461 LYS TYR MET LEU PHE THR MET ILE PHE VAL ILE SER SER
SEQRES 25 I 461 ILE ILE VAL THR VAL VAL VAL ILE ASN THR HIS HIS ARG
SEQRES 26 I 461 SER PRO SER THR HIS THR MET PRO GLN TRP VAL ARG LYS
SEQRES 27 I 461 ILE PHE ILE ASN THR ILE PRO ASN VAL MET PHE PHE SER
SEQRES 28 I 461 THR MET LYS ARG ALA SER LYS GLU LYS GLN GLU ASN LYS
SEQRES 29 I 461 ILE PHE ALA ASP ASP ILE ASP ILE SER ASP ILE SER GLY
SEQRES 30 I 461 LYS GLN VAL THR GLY GLU VAL ILE PHE GLN THR PRO LEU
SEQRES 31 I 461 ILE LYS ASN PRO ASP VAL LYS SER ALA ILE GLU GLY VAL
SEQRES 32 I 461 LYS TYR ILE ALA GLU HIS MET LYS SER ASP GLU GLU SER
SEQRES 33 I 461 SER ASN ALA ALA GLU GLU TRP LYS TYR VAL ALA MET VAL
SEQRES 34 I 461 ILE ASP HIS ILE LEU LEU CYS VAL PHE MET LEU ILE CYS
SEQRES 35 I 461 ILE ILE GLY THR VAL SER VAL PHE ALA GLY ARG LEU ILE
SEQRES 36 I 461 GLU LEU SER GLN GLU GLY
SEQRES 1 J 505 MET VAL LEU THR LEU LEU LEU ILE ILE CYS LEU ALA LEU
SEQRES 2 J 505 GLU VAL ARG SER ASN GLU GLU GLY ARG LEU ILE GLU LYS
SEQRES 3 J 505 LEU LEU GLY ASP TYR ASP LYS ARG ILE LYS PRO ALA LYS
SEQRES 4 J 505 THR LEU ASP HIS VAL ILE ASP VAL THR LEU LYS LEU THR
SEQRES 5 J 505 LEU THR ASN LEU ILE SER LEU ASN GLU LYS GLU GLU ALA
SEQRES 6 J 505 LEU THR THR ASN VAL TRP ILE GLU ILE GLN TRP ASN ASP
SEQRES 7 J 505 TYR ARG LEU SER TRP ASN THR SER GLU TYR GLU GLY ILE
SEQRES 8 J 505 ASP LEU VAL ARG ILE PRO SER GLU LEU LEU TRP LEU PRO
SEQRES 9 J 505 ASP VAL VAL LEU GLU ASN ASN VAL ASP GLY GLN PHE GLU
SEQRES 10 J 505 VAL ALA TYR TYR ALA ASN VAL LEU VAL TYR ASN ASP GLY
SEQRES 11 J 505 SER MET TYR TRP LEU PRO PRO ALA ILE TYR ARG SER THR
SEQRES 12 J 505 CYS PRO ILE ALA VAL THR TYR PHE PRO PHE ASP TRP GLN
SEQRES 13 J 505 ASN CYS SER LEU VAL PHE ARG SER GLN THR TYR ASN ALA
SEQRES 14 J 505 HIS GLU VAL ASN LEU GLN LEU SER ALA GLU GLU GLY GLU
SEQRES 15 J 505 VAL VAL GLU TRP ILE HIS ILE ASP PRO GLU ASP PHE THR
SEQRES 16 J 505 GLU ASN GLY GLU TRP THR ILE ARG HIS ARG PRO ALA LYS
SEQRES 17 J 505 LYS ASN TYR ASN TRP GLN LEU THR LYS ASP ASP ILE ASP
SEQRES 18 J 505 PHE GLN GLU ILE ILE PHE PHE LEU ILE ILE GLN ARG LYS
SEQRES 19 J 505 PRO LEU PHE TYR ILE ILE ASN ILE ILE ALA PRO CYS VAL
SEQRES 20 J 505 LEU ILE SER SER LEU VAL VAL LEU VAL TYR PHE LEU PRO
SEQRES 21 J 505 ALA GLN ALA GLY GLY GLN LYS CYS THR LEU SER ILE SER
SEQRES 22 J 505 VAL LEU LEU ALA GLN THR ILE PHE LEU PHE LEU ILE ALA
SEQRES 23 J 505 GLN LYS VAL PRO GLU THR SER LEU ASN VAL PRO LEU ILE
SEQRES 24 J 505 GLY LYS TYR LEU ILE PHE VAL MET PHE VAL SER LEU VAL
SEQRES 25 J 505 ILE VAL THR ASN CYS VAL ILE VAL LEU ASN VAL SER LEU
SEQRES 26 J 505 ARG THR PRO ASN THR HIS SER LEU SER GLU LYS ILE LYS
SEQRES 27 J 505 HIS LEU PHE LEU GLU PHE LEU PRO LYS TYR LEU GLY MET
SEQRES 28 J 505 HIS LEU GLU PRO SER GLU GLU THR PRO GLU LYS PRO GLN
SEQRES 29 J 505 PRO ARG ARG ARG SER SER PHE GLY ILE MET ILE LYS ALA
SEQRES 30 J 505 GLU GLU TYR ILE LEU LYS LYS PRO ARG SER GLU LEU MET
SEQRES 31 J 505 PHE GLU GLU GLN LYS ASP ARG HIS GLY LEU LYS ARG VAL
SEQRES 32 J 505 ASN LYS MET THR SER ASP ILE ASP ILE GLY THR THR VAL
SEQRES 33 J 505 ASP LEU TYR LYS ASP LEU ALA ASN PHE ALA PRO GLU ILE
SEQRES 34 J 505 LYS SER CYS VAL GLU ALA CYS ASN PHE ILE ALA LYS SER
SEQRES 35 J 505 THR LYS GLU GLN ASN ASP SER GLY SER GLU ASN GLU ASN
SEQRES 36 J 505 TRP VAL LEU ILE GLY LYS VAL ILE ASP LYS ALA CYS PHE
SEQRES 37 J 505 TRP ILE ALA LEU LEU LEU PHE SER LEU GLY THR LEU ALA
SEQRES 38 J 505 ILE PHE LEU THR GLY HIS LEU ASN GLN VAL PRO GLU PHE
SEQRES 39 J 505 PRO PHE PRO GLY ASP PRO ARG LYS TYR VAL PRO
SEQRES 1 K 461 MET ILE LEU CYS SER TYR TRP HIS VAL GLY LEU VAL LEU
SEQRES 2 K 461 LEU LEU PHE SER CYS CYS GLY LEU VAL LEU GLY SER GLU
SEQRES 3 K 461 HIS GLU THR ARG LEU VAL ALA ASN LEU LEU GLU ASN TYR
SEQRES 4 K 461 ASN LYS VAL ILE ARG PRO VAL GLU HIS HIS THR HIS PHE
SEQRES 5 K 461 VAL ASP ILE THR VAL GLY LEU GLN LEU ILE GLN LEU ILE
SEQRES 6 K 461 ASN VAL ASP GLU VAL ASN GLN ILE VAL GLU THR ASN VAL
SEQRES 7 K 461 ARG LEU ARG GLN GLN TRP ILE ASP VAL ARG LEU ARG TRP
SEQRES 8 K 461 ASN PRO ALA ASP TYR GLY GLY ILE LYS LYS ILE ARG LEU
SEQRES 9 K 461 PRO SER ASP ASP VAL TRP LEU PRO ASP LEU VAL LEU TYR
SEQRES 10 K 461 ASN ASN ALA ASP GLY ASP PHE ALA ILE VAL HIS MET THR
SEQRES 11 K 461 LYS LEU LEU LEU ASP TYR THR GLY LYS ILE MET TRP THR
SEQRES 12 K 461 PRO PRO ALA ILE PHE LYS SER TYR CYS GLU ILE ILE VAL
SEQRES 13 K 461 THR HIS PHE PRO PHE ASP GLN GLN ASN CYS THR MET LYS
SEQRES 14 K 461 LEU GLY ILE TRP THR TYR ASP GLY THR LYS VAL SER ILE
SEQRES 15 K 461 SER PRO GLU SER ASP ARG PRO ASP LEU SER THR PHE MET
SEQRES 16 K 461 GLU SER GLY GLU TRP VAL MET LYS ASP TYR ARG GLY TRP
SEQRES 17 K 461 LYS HIS TRP VAL TYR TYR THR CYS CYS PRO ASP THR PRO
SEQRES 18 K 461 TYR LEU ASP ILE THR TYR HIS PHE ILE MET GLN ARG ILE
SEQRES 19 K 461 PRO LEU TYR PHE VAL VAL ASN VAL ILE ILE PRO CYS LEU
SEQRES 20 K 461 LEU PHE SER PHE LEU THR VAL LEU VAL PHE TYR LEU PRO
SEQRES 21 K 461 THR ASP SER GLY GLU LYS MET THR LEU SER ILE SER VAL
SEQRES 22 K 461 LEU LEU SER LEU THR VAL PHE LEU LEU VAL ILE VAL GLU
SEQRES 23 K 461 LEU ILE PRO SER THR SER SER ALA VAL PRO LEU ILE GLY
SEQRES 24 K 461 LYS TYR MET LEU PHE THR MET ILE PHE VAL ILE SER SER
SEQRES 25 K 461 ILE ILE VAL THR VAL VAL VAL ILE ASN THR HIS HIS ARG
SEQRES 26 K 461 SER PRO SER THR HIS THR MET PRO GLN TRP VAL ARG LYS
SEQRES 27 K 461 ILE PHE ILE ASN THR ILE PRO ASN VAL MET PHE PHE SER
SEQRES 28 K 461 THR MET LYS ARG ALA SER LYS GLU LYS GLN GLU ASN LYS
SEQRES 29 K 461 ILE PHE ALA ASP ASP ILE ASP ILE SER ASP ILE SER GLY
SEQRES 30 K 461 LYS GLN VAL THR GLY GLU VAL ILE PHE GLN THR PRO LEU
SEQRES 31 K 461 ILE LYS ASN PRO ASP VAL LYS SER ALA ILE GLU GLY VAL
SEQRES 32 K 461 LYS TYR ILE ALA GLU HIS MET LYS SER ASP GLU GLU SER
SEQRES 33 K 461 SER ASN ALA ALA GLU GLU TRP LYS TYR VAL ALA MET VAL
SEQRES 34 K 461 ILE ASP HIS ILE LEU LEU CYS VAL PHE MET LEU ILE CYS
SEQRES 35 K 461 ILE ILE GLY THR VAL SER VAL PHE ALA GLY ARG LEU ILE
SEQRES 36 K 461 GLU LEU SER GLN GLU GLY
SEQRES 1 L 493 MET GLU ASP VAL ARG ARG MET ALA LEU GLY LEU VAL VAL
SEQRES 2 L 493 MET MET ALA LEU ALA LEU SER GLY VAL GLY ALA SER VAL
SEQRES 3 L 493 MET GLU ASP THR LEU LEU SER VAL LEU PHE GLU ASN TYR
SEQRES 4 L 493 ASN PRO LYS VAL ARG PRO SER GLN THR VAL GLY ASP LYS
SEQRES 5 L 493 VAL THR VAL ARG VAL GLY LEU THR LEU THR SER LEU LEU
SEQRES 6 L 493 ILE LEU ASN GLU LYS ASN GLU GLU MET THR THR SER VAL
SEQRES 7 L 493 PHE LEU ASN LEU ALA TRP THR ASP TYR ARG LEU GLN TRP
SEQRES 8 L 493 ASP PRO ALA ALA TYR GLU GLY ILE LYS ASP LEU SER ILE
SEQRES 9 L 493 PRO SER ASP ASP VAL TRP GLN PRO ASP ILE VAL LEU MET
SEQRES 10 L 493 ASN ASN ASN ASP GLY SER PHE GLU ILE THR LEU HIS VAL
SEQRES 11 L 493 ASN VAL LEU VAL GLN HIS THR GLY ALA VAL SER TRP HIS
SEQRES 12 L 493 PRO SER ALA ILE TYR ARG SER SER CYS THR ILE LYS VAL
SEQRES 13 L 493 MET TYR PHE PRO PHE ASP TRP GLN ASN CYS THR MET VAL
SEQRES 14 L 493 PHE LYS SER TYR THR TYR ASP THR SER GLU VAL ILE LEU
SEQRES 15 L 493 GLN HIS ALA LEU ASP ALA LYS GLY GLU ARG GLU VAL LYS
SEQRES 16 L 493 GLU ILE MET ILE ASN GLN ASP ALA PHE THR GLU ASN GLY
SEQRES 17 L 493 GLN TRP SER ILE GLU HIS LYS PRO SER ARG LYS ASN TRP
SEQRES 18 L 493 ARG SER ASP ASP PRO SER TYR GLU ASP VAL THR PHE TYR
SEQRES 19 L 493 LEU ILE ILE GLN ARG LYS PRO LEU PHE TYR ILE VAL TYR
SEQRES 20 L 493 THR ILE VAL PRO CYS ILE LEU ILE SER ILE LEU ALA ILE
SEQRES 21 L 493 LEU VAL PHE TYR LEU PRO PRO ASP ALA GLY GLU LYS MET
SEQRES 22 L 493 SER LEU SER ILE SER ALA LEU LEU ALA LEU THR VAL PHE
SEQRES 23 L 493 LEU LEU LEU LEU ALA ASP LYS VAL PRO GLU THR SER LEU
SEQRES 24 L 493 SER VAL PRO ILE ILE ILE SER TYR LEU MET PHE ILE MET
SEQRES 25 L 493 ILE LEU VAL ALA PHE SER VAL ILE LEU SER VAL VAL VAL
SEQRES 26 L 493 LEU ASN LEU HIS HIS ARG SER PRO ASN THR HIS THR MET
SEQRES 27 L 493 PRO ASN TRP ILE ARG GLN ILE PHE ILE GLU THR LEU PRO
SEQRES 28 L 493 PRO PHE LEU TRP ILE GLN ARG PRO VAL THR THR PRO SER
SEQRES 29 L 493 PRO ASP SER LYS PRO THR ILE ILE SER ARG ALA ASN ASP
SEQRES 30 L 493 GLU TYR PHE ILE ARG LYS PRO ALA GLY ASP PHE VAL CYS
SEQRES 31 L 493 PRO VAL ASP ASN ALA ARG VAL ALA VAL GLN PRO GLU ARG
SEQRES 32 L 493 LEU PHE SER GLU MET LYS TRP HIS LEU ASN GLY LEU THR
SEQRES 33 L 493 GLN PRO VAL THR LEU PRO GLN ASP LEU LYS GLU ALA VAL
SEQRES 34 L 493 GLU ALA ILE LYS TYR ILE ALA GLU GLN LEU GLU SER ALA
SEQRES 35 L 493 SER GLU PHE ASP ASP LEU LYS LYS ASP TRP GLN TYR VAL
SEQRES 36 L 493 ALA MET VAL ALA ASP ARG LEU PHE LEU TYR ILE PHE ILE
SEQRES 37 L 493 THR MET CYS SER ILE GLY THR PHE SER ILE PHE LEU ASP
SEQRES 38 L 493 ALA SER HIS ASN VAL PRO PRO ASP ASN PRO PHE ALA
SEQRES 1 M 522 MET GLY ASN ILE HIS PHE VAL TYR LEU LEU ILE SER CYS
SEQRES 2 M 522 LEU TYR TYR SER GLY CYS SER GLY VAL ASN GLU GLU GLU
SEQRES 3 M 522 ARG LEU ILE ASN ASP LEU LEU ILE VAL ASN LYS TYR ASN
SEQRES 4 M 522 LYS HIS VAL ARG PRO VAL LYS HIS ASN ASN GLU VAL VAL
SEQRES 5 M 522 ASN ILE ALA LEU SER LEU THR LEU SER ASN LEU ILE SER
SEQRES 6 M 522 LEU LYS GLU THR ASP GLU THR LEU THR THR ASN VAL TRP
SEQRES 7 M 522 MET ASP HIS ALA TRP TYR ASP HIS ARG LEU THR TRP ASN
SEQRES 8 M 522 ALA SER GLU TYR SER ASP ILE SER ILE LEU ARG LEU ARG
SEQRES 9 M 522 PRO GLU LEU ILE TRP ILE PRO ASP ILE VAL LEU GLN ASN
SEQRES 10 M 522 ASN ASN ASP GLY GLN TYR ASN VAL ALA TYR PHE CYS ASN
SEQRES 11 M 522 VAL LEU VAL ARG PRO ASN GLY TYR VAL THR TRP LEU PRO
SEQRES 12 M 522 PRO ALA ILE PHE ARG SER SER CYS PRO ILE ASN VAL LEU
SEQRES 13 M 522 TYR PHE PRO PHE ASP TRP GLN ASN CYS SER LEU LYS PHE
SEQRES 14 M 522 THR ALA LEU ASN TYR ASN ALA ASN GLU ILE SER MET ASP
SEQRES 15 M 522 LEU MET THR ASP THR ILE ASP GLY LYS ASP TYR PRO ILE
SEQRES 16 M 522 GLU TRP ILE ILE ILE ASP PRO GLU ALA PHE THR GLU ASN
SEQRES 17 M 522 GLY GLU TRP GLU ILE ILE HIS LYS PRO ALA LYS LYS ASN
SEQRES 18 M 522 ILE TYR GLY ASP LYS PHE PRO ASN GLY THR ASN TYR GLN
SEQRES 19 M 522 ASP VAL THR PHE TYR LEU ILE ILE ARG ARG LYS PRO LEU
SEQRES 20 M 522 PHE TYR VAL ILE ASN PHE ILE THR PRO CYS VAL LEU ILE
SEQRES 21 M 522 SER PHE LEU ALA ALA LEU ALA PHE TYR LEU PRO ALA GLU
SEQRES 22 M 522 SER GLY GLU LYS MET SER THR ALA ILE CYS VAL LEU LEU
SEQRES 23 M 522 ALA GLN ALA VAL PHE LEU LEU LEU THR SER GLN ARG LEU
SEQRES 24 M 522 PRO GLU THR ALA LEU ALA VAL PRO LEU ILE GLY LYS TYR
SEQRES 25 M 522 LEU MET PHE ILE MET SER LEU VAL THR GLY VAL VAL VAL
SEQRES 26 M 522 ASN CYS GLY ILE VAL LEU ASN PHE HIS PHE ARG THR PRO
SEQRES 27 M 522 SER THR HIS VAL LEU SER THR ARG VAL LYS GLN ILE PHE
SEQRES 28 M 522 LEU GLU LYS LEU PRO ARG ILE LEU HIS MET SER ARG VAL
SEQRES 29 M 522 ASP GLU ILE GLU GLN PRO ASP TRP GLN ASN ASP LEU LYS
SEQRES 30 M 522 LEU ARG ARG SER SER SER VAL GLY TYR ILE SER LYS ALA
SEQRES 31 M 522 GLN GLU TYR PHE ASN ILE LYS SER ARG SER GLU LEU MET
SEQRES 32 M 522 PHE GLU LYS GLN SER GLU ARG HIS GLY LEU VAL PRO ARG
SEQRES 33 M 522 VAL THR PRO ARG ILE GLY PHE GLY ASN ASN ASN GLU ASN
SEQRES 34 M 522 ILE ALA ALA SER ASP GLN LEU HIS ASP GLU ILE LYS SER
SEQRES 35 M 522 GLY ILE ASP SER THR ASN TYR ILE VAL LYS GLN ILE LYS
SEQRES 36 M 522 GLU LYS ASN ALA TYR ASP GLU GLU VAL GLY ASN TRP ASN
SEQRES 37 M 522 LEU VAL GLY GLN THR ILE ASP ARG LEU SER MET PHE ILE
SEQRES 38 M 522 ILE THR PRO VAL MET VAL LEU GLY THR ILE PHE ILE PHE
SEQRES 39 M 522 VAL MET GLY ASN PHE ASN ARG PRO PRO ALA LYS PRO PHE
SEQRES 40 M 522 GLU GLY ASP PRO PHE ASP TYR SER SER ASP HIS PRO ARG
SEQRES 41 M 522 CYS ALA
SEQRES 1 N 461 MET ILE LEU CYS SER TYR TRP HIS VAL GLY LEU VAL LEU
SEQRES 2 N 461 LEU LEU PHE SER CYS CYS GLY LEU VAL LEU GLY SER GLU
SEQRES 3 N 461 HIS GLU THR ARG LEU VAL ALA ASN LEU LEU GLU ASN TYR
SEQRES 4 N 461 ASN LYS VAL ILE ARG PRO VAL GLU HIS HIS THR HIS PHE
SEQRES 5 N 461 VAL ASP ILE THR VAL GLY LEU GLN LEU ILE GLN LEU ILE
SEQRES 6 N 461 ASN VAL ASP GLU VAL ASN GLN ILE VAL GLU THR ASN VAL
SEQRES 7 N 461 ARG LEU ARG GLN GLN TRP ILE ASP VAL ARG LEU ARG TRP
SEQRES 8 N 461 ASN PRO ALA ASP TYR GLY GLY ILE LYS LYS ILE ARG LEU
SEQRES 9 N 461 PRO SER ASP ASP VAL TRP LEU PRO ASP LEU VAL LEU TYR
SEQRES 10 N 461 ASN ASN ALA ASP GLY ASP PHE ALA ILE VAL HIS MET THR
SEQRES 11 N 461 LYS LEU LEU LEU ASP TYR THR GLY LYS ILE MET TRP THR
SEQRES 12 N 461 PRO PRO ALA ILE PHE LYS SER TYR CYS GLU ILE ILE VAL
SEQRES 13 N 461 THR HIS PHE PRO PHE ASP GLN GLN ASN CYS THR MET LYS
SEQRES 14 N 461 LEU GLY ILE TRP THR TYR ASP GLY THR LYS VAL SER ILE
SEQRES 15 N 461 SER PRO GLU SER ASP ARG PRO ASP LEU SER THR PHE MET
SEQRES 16 N 461 GLU SER GLY GLU TRP VAL MET LYS ASP TYR ARG GLY TRP
SEQRES 17 N 461 LYS HIS TRP VAL TYR TYR THR CYS CYS PRO ASP THR PRO
SEQRES 18 N 461 TYR LEU ASP ILE THR TYR HIS PHE ILE MET GLN ARG ILE
SEQRES 19 N 461 PRO LEU TYR PHE VAL VAL ASN VAL ILE ILE PRO CYS LEU
SEQRES 20 N 461 LEU PHE SER PHE LEU THR VAL LEU VAL PHE TYR LEU PRO
SEQRES 21 N 461 THR ASP SER GLY GLU LYS MET THR LEU SER ILE SER VAL
SEQRES 22 N 461 LEU LEU SER LEU THR VAL PHE LEU LEU VAL ILE VAL GLU
SEQRES 23 N 461 LEU ILE PRO SER THR SER SER ALA VAL PRO LEU ILE GLY
SEQRES 24 N 461 LYS TYR MET LEU PHE THR MET ILE PHE VAL ILE SER SER
SEQRES 25 N 461 ILE ILE VAL THR VAL VAL VAL ILE ASN THR HIS HIS ARG
SEQRES 26 N 461 SER PRO SER THR HIS THR MET PRO GLN TRP VAL ARG LYS
SEQRES 27 N 461 ILE PHE ILE ASN THR ILE PRO ASN VAL MET PHE PHE SER
SEQRES 28 N 461 THR MET LYS ARG ALA SER LYS GLU LYS GLN GLU ASN LYS
SEQRES 29 N 461 ILE PHE ALA ASP ASP ILE ASP ILE SER ASP ILE SER GLY
SEQRES 30 N 461 LYS GLN VAL THR GLY GLU VAL ILE PHE GLN THR PRO LEU
SEQRES 31 N 461 ILE LYS ASN PRO ASP VAL LYS SER ALA ILE GLU GLY VAL
SEQRES 32 N 461 LYS TYR ILE ALA GLU HIS MET LYS SER ASP GLU GLU SER
SEQRES 33 N 461 SER ASN ALA ALA GLU GLU TRP LYS TYR VAL ALA MET VAL
SEQRES 34 N 461 ILE ASP HIS ILE LEU LEU CYS VAL PHE MET LEU ILE CYS
SEQRES 35 N 461 ILE ILE GLY THR VAL SER VAL PHE ALA GLY ARG LEU ILE
SEQRES 36 N 461 GLU LEU SER GLN GLU GLY
SEQRES 1 O 505 MET VAL LEU THR LEU LEU LEU ILE ILE CYS LEU ALA LEU
SEQRES 2 O 505 GLU VAL ARG SER ASN GLU GLU GLY ARG LEU ILE GLU LYS
SEQRES 3 O 505 LEU LEU GLY ASP TYR ASP LYS ARG ILE LYS PRO ALA LYS
SEQRES 4 O 505 THR LEU ASP HIS VAL ILE ASP VAL THR LEU LYS LEU THR
SEQRES 5 O 505 LEU THR ASN LEU ILE SER LEU ASN GLU LYS GLU GLU ALA
SEQRES 6 O 505 LEU THR THR ASN VAL TRP ILE GLU ILE GLN TRP ASN ASP
SEQRES 7 O 505 TYR ARG LEU SER TRP ASN THR SER GLU TYR GLU GLY ILE
SEQRES 8 O 505 ASP LEU VAL ARG ILE PRO SER GLU LEU LEU TRP LEU PRO
SEQRES 9 O 505 ASP VAL VAL LEU GLU ASN ASN VAL ASP GLY GLN PHE GLU
SEQRES 10 O 505 VAL ALA TYR TYR ALA ASN VAL LEU VAL TYR ASN ASP GLY
SEQRES 11 O 505 SER MET TYR TRP LEU PRO PRO ALA ILE TYR ARG SER THR
SEQRES 12 O 505 CYS PRO ILE ALA VAL THR TYR PHE PRO PHE ASP TRP GLN
SEQRES 13 O 505 ASN CYS SER LEU VAL PHE ARG SER GLN THR TYR ASN ALA
SEQRES 14 O 505 HIS GLU VAL ASN LEU GLN LEU SER ALA GLU GLU GLY GLU
SEQRES 15 O 505 VAL VAL GLU TRP ILE HIS ILE ASP PRO GLU ASP PHE THR
SEQRES 16 O 505 GLU ASN GLY GLU TRP THR ILE ARG HIS ARG PRO ALA LYS
SEQRES 17 O 505 LYS ASN TYR ASN TRP GLN LEU THR LYS ASP ASP ILE ASP
SEQRES 18 O 505 PHE GLN GLU ILE ILE PHE PHE LEU ILE ILE GLN ARG LYS
SEQRES 19 O 505 PRO LEU PHE TYR ILE ILE ASN ILE ILE ALA PRO CYS VAL
SEQRES 20 O 505 LEU ILE SER SER LEU VAL VAL LEU VAL TYR PHE LEU PRO
SEQRES 21 O 505 ALA GLN ALA GLY GLY GLN LYS CYS THR LEU SER ILE SER
SEQRES 22 O 505 VAL LEU LEU ALA GLN THR ILE PHE LEU PHE LEU ILE ALA
SEQRES 23 O 505 GLN LYS VAL PRO GLU THR SER LEU ASN VAL PRO LEU ILE
SEQRES 24 O 505 GLY LYS TYR LEU ILE PHE VAL MET PHE VAL SER LEU VAL
SEQRES 25 O 505 ILE VAL THR ASN CYS VAL ILE VAL LEU ASN VAL SER LEU
SEQRES 26 O 505 ARG THR PRO ASN THR HIS SER LEU SER GLU LYS ILE LYS
SEQRES 27 O 505 HIS LEU PHE LEU GLU PHE LEU PRO LYS TYR LEU GLY MET
SEQRES 28 O 505 HIS LEU GLU PRO SER GLU GLU THR PRO GLU LYS PRO GLN
SEQRES 29 O 505 PRO ARG ARG ARG SER SER PHE GLY ILE MET ILE LYS ALA
SEQRES 30 O 505 GLU GLU TYR ILE LEU LYS LYS PRO ARG SER GLU LEU MET
SEQRES 31 O 505 PHE GLU GLU GLN LYS ASP ARG HIS GLY LEU LYS ARG VAL
SEQRES 32 O 505 ASN LYS MET THR SER ASP ILE ASP ILE GLY THR THR VAL
SEQRES 33 O 505 ASP LEU TYR LYS ASP LEU ALA ASN PHE ALA PRO GLU ILE
SEQRES 34 O 505 LYS SER CYS VAL GLU ALA CYS ASN PHE ILE ALA LYS SER
SEQRES 35 O 505 THR LYS GLU GLN ASN ASP SER GLY SER GLU ASN GLU ASN
SEQRES 36 O 505 TRP VAL LEU ILE GLY LYS VAL ILE ASP LYS ALA CYS PHE
SEQRES 37 O 505 TRP ILE ALA LEU LEU LEU PHE SER LEU GLY THR LEU ALA
SEQRES 38 O 505 ILE PHE LEU THR GLY HIS LEU ASN GLN VAL PRO GLU PHE
SEQRES 39 O 505 PRO PHE PRO GLY ASP PRO ARG LYS TYR VAL PRO
SEQRES 1 P 461 MET ILE LEU CYS SER TYR TRP HIS VAL GLY LEU VAL LEU
SEQRES 2 P 461 LEU LEU PHE SER CYS CYS GLY LEU VAL LEU GLY SER GLU
SEQRES 3 P 461 HIS GLU THR ARG LEU VAL ALA ASN LEU LEU GLU ASN TYR
SEQRES 4 P 461 ASN LYS VAL ILE ARG PRO VAL GLU HIS HIS THR HIS PHE
SEQRES 5 P 461 VAL ASP ILE THR VAL GLY LEU GLN LEU ILE GLN LEU ILE
SEQRES 6 P 461 ASN VAL ASP GLU VAL ASN GLN ILE VAL GLU THR ASN VAL
SEQRES 7 P 461 ARG LEU ARG GLN GLN TRP ILE ASP VAL ARG LEU ARG TRP
SEQRES 8 P 461 ASN PRO ALA ASP TYR GLY GLY ILE LYS LYS ILE ARG LEU
SEQRES 9 P 461 PRO SER ASP ASP VAL TRP LEU PRO ASP LEU VAL LEU TYR
SEQRES 10 P 461 ASN ASN ALA ASP GLY ASP PHE ALA ILE VAL HIS MET THR
SEQRES 11 P 461 LYS LEU LEU LEU ASP TYR THR GLY LYS ILE MET TRP THR
SEQRES 12 P 461 PRO PRO ALA ILE PHE LYS SER TYR CYS GLU ILE ILE VAL
SEQRES 13 P 461 THR HIS PHE PRO PHE ASP GLN GLN ASN CYS THR MET LYS
SEQRES 14 P 461 LEU GLY ILE TRP THR TYR ASP GLY THR LYS VAL SER ILE
SEQRES 15 P 461 SER PRO GLU SER ASP ARG PRO ASP LEU SER THR PHE MET
SEQRES 16 P 461 GLU SER GLY GLU TRP VAL MET LYS ASP TYR ARG GLY TRP
SEQRES 17 P 461 LYS HIS TRP VAL TYR TYR THR CYS CYS PRO ASP THR PRO
SEQRES 18 P 461 TYR LEU ASP ILE THR TYR HIS PHE ILE MET GLN ARG ILE
SEQRES 19 P 461 PRO LEU TYR PHE VAL VAL ASN VAL ILE ILE PRO CYS LEU
SEQRES 20 P 461 LEU PHE SER PHE LEU THR VAL LEU VAL PHE TYR LEU PRO
SEQRES 21 P 461 THR ASP SER GLY GLU LYS MET THR LEU SER ILE SER VAL
SEQRES 22 P 461 LEU LEU SER LEU THR VAL PHE LEU LEU VAL ILE VAL GLU
SEQRES 23 P 461 LEU ILE PRO SER THR SER SER ALA VAL PRO LEU ILE GLY
SEQRES 24 P 461 LYS TYR MET LEU PHE THR MET ILE PHE VAL ILE SER SER
SEQRES 25 P 461 ILE ILE VAL THR VAL VAL VAL ILE ASN THR HIS HIS ARG
SEQRES 26 P 461 SER PRO SER THR HIS THR MET PRO GLN TRP VAL ARG LYS
SEQRES 27 P 461 ILE PHE ILE ASN THR ILE PRO ASN VAL MET PHE PHE SER
SEQRES 28 P 461 THR MET LYS ARG ALA SER LYS GLU LYS GLN GLU ASN LYS
SEQRES 29 P 461 ILE PHE ALA ASP ASP ILE ASP ILE SER ASP ILE SER GLY
SEQRES 30 P 461 LYS GLN VAL THR GLY GLU VAL ILE PHE GLN THR PRO LEU
SEQRES 31 P 461 ILE LYS ASN PRO ASP VAL LYS SER ALA ILE GLU GLY VAL
SEQRES 32 P 461 LYS TYR ILE ALA GLU HIS MET LYS SER ASP GLU GLU SER
SEQRES 33 P 461 SER ASN ALA ALA GLU GLU TRP LYS TYR VAL ALA MET VAL
SEQRES 34 P 461 ILE ASP HIS ILE LEU LEU CYS VAL PHE MET LEU ILE CYS
SEQRES 35 P 461 ILE ILE GLY THR VAL SER VAL PHE ALA GLY ARG LEU ILE
SEQRES 36 P 461 GLU LEU SER GLN GLU GLY
SEQRES 1 Q 493 MET GLU ASP VAL ARG ARG MET ALA LEU GLY LEU VAL VAL
SEQRES 2 Q 493 MET MET ALA LEU ALA LEU SER GLY VAL GLY ALA SER VAL
SEQRES 3 Q 493 MET GLU ASP THR LEU LEU SER VAL LEU PHE GLU ASN TYR
SEQRES 4 Q 493 ASN PRO LYS VAL ARG PRO SER GLN THR VAL GLY ASP LYS
SEQRES 5 Q 493 VAL THR VAL ARG VAL GLY LEU THR LEU THR SER LEU LEU
SEQRES 6 Q 493 ILE LEU ASN GLU LYS ASN GLU GLU MET THR THR SER VAL
SEQRES 7 Q 493 PHE LEU ASN LEU ALA TRP THR ASP TYR ARG LEU GLN TRP
SEQRES 8 Q 493 ASP PRO ALA ALA TYR GLU GLY ILE LYS ASP LEU SER ILE
SEQRES 9 Q 493 PRO SER ASP ASP VAL TRP GLN PRO ASP ILE VAL LEU MET
SEQRES 10 Q 493 ASN ASN ASN ASP GLY SER PHE GLU ILE THR LEU HIS VAL
SEQRES 11 Q 493 ASN VAL LEU VAL GLN HIS THR GLY ALA VAL SER TRP HIS
SEQRES 12 Q 493 PRO SER ALA ILE TYR ARG SER SER CYS THR ILE LYS VAL
SEQRES 13 Q 493 MET TYR PHE PRO PHE ASP TRP GLN ASN CYS THR MET VAL
SEQRES 14 Q 493 PHE LYS SER TYR THR TYR ASP THR SER GLU VAL ILE LEU
SEQRES 15 Q 493 GLN HIS ALA LEU ASP ALA LYS GLY GLU ARG GLU VAL LYS
SEQRES 16 Q 493 GLU ILE MET ILE ASN GLN ASP ALA PHE THR GLU ASN GLY
SEQRES 17 Q 493 GLN TRP SER ILE GLU HIS LYS PRO SER ARG LYS ASN TRP
SEQRES 18 Q 493 ARG SER ASP ASP PRO SER TYR GLU ASP VAL THR PHE TYR
SEQRES 19 Q 493 LEU ILE ILE GLN ARG LYS PRO LEU PHE TYR ILE VAL TYR
SEQRES 20 Q 493 THR ILE VAL PRO CYS ILE LEU ILE SER ILE LEU ALA ILE
SEQRES 21 Q 493 LEU VAL PHE TYR LEU PRO PRO ASP ALA GLY GLU LYS MET
SEQRES 22 Q 493 SER LEU SER ILE SER ALA LEU LEU ALA LEU THR VAL PHE
SEQRES 23 Q 493 LEU LEU LEU LEU ALA ASP LYS VAL PRO GLU THR SER LEU
SEQRES 24 Q 493 SER VAL PRO ILE ILE ILE SER TYR LEU MET PHE ILE MET
SEQRES 25 Q 493 ILE LEU VAL ALA PHE SER VAL ILE LEU SER VAL VAL VAL
SEQRES 26 Q 493 LEU ASN LEU HIS HIS ARG SER PRO ASN THR HIS THR MET
SEQRES 27 Q 493 PRO ASN TRP ILE ARG GLN ILE PHE ILE GLU THR LEU PRO
SEQRES 28 Q 493 PRO PHE LEU TRP ILE GLN ARG PRO VAL THR THR PRO SER
SEQRES 29 Q 493 PRO ASP SER LYS PRO THR ILE ILE SER ARG ALA ASN ASP
SEQRES 30 Q 493 GLU TYR PHE ILE ARG LYS PRO ALA GLY ASP PHE VAL CYS
SEQRES 31 Q 493 PRO VAL ASP ASN ALA ARG VAL ALA VAL GLN PRO GLU ARG
SEQRES 32 Q 493 LEU PHE SER GLU MET LYS TRP HIS LEU ASN GLY LEU THR
SEQRES 33 Q 493 GLN PRO VAL THR LEU PRO GLN ASP LEU LYS GLU ALA VAL
SEQRES 34 Q 493 GLU ALA ILE LYS TYR ILE ALA GLU GLN LEU GLU SER ALA
SEQRES 35 Q 493 SER GLU PHE ASP ASP LEU LYS LYS ASP TRP GLN TYR VAL
SEQRES 36 Q 493 ALA MET VAL ALA ASP ARG LEU PHE LEU TYR ILE PHE ILE
SEQRES 37 Q 493 THR MET CYS SER ILE GLY THR PHE SER ILE PHE LEU ASP
SEQRES 38 Q 493 ALA SER HIS ASN VAL PRO PRO ASP ASN PRO PHE ALA
SEQRES 1 R 522 MET GLY ASN ILE HIS PHE VAL TYR LEU LEU ILE SER CYS
SEQRES 2 R 522 LEU TYR TYR SER GLY CYS SER GLY VAL ASN GLU GLU GLU
SEQRES 3 R 522 ARG LEU ILE ASN ASP LEU LEU ILE VAL ASN LYS TYR ASN
SEQRES 4 R 522 LYS HIS VAL ARG PRO VAL LYS HIS ASN ASN GLU VAL VAL
SEQRES 5 R 522 ASN ILE ALA LEU SER LEU THR LEU SER ASN LEU ILE SER
SEQRES 6 R 522 LEU LYS GLU THR ASP GLU THR LEU THR THR ASN VAL TRP
SEQRES 7 R 522 MET ASP HIS ALA TRP TYR ASP HIS ARG LEU THR TRP ASN
SEQRES 8 R 522 ALA SER GLU TYR SER ASP ILE SER ILE LEU ARG LEU ARG
SEQRES 9 R 522 PRO GLU LEU ILE TRP ILE PRO ASP ILE VAL LEU GLN ASN
SEQRES 10 R 522 ASN ASN ASP GLY GLN TYR ASN VAL ALA TYR PHE CYS ASN
SEQRES 11 R 522 VAL LEU VAL ARG PRO ASN GLY TYR VAL THR TRP LEU PRO
SEQRES 12 R 522 PRO ALA ILE PHE ARG SER SER CYS PRO ILE ASN VAL LEU
SEQRES 13 R 522 TYR PHE PRO PHE ASP TRP GLN ASN CYS SER LEU LYS PHE
SEQRES 14 R 522 THR ALA LEU ASN TYR ASN ALA ASN GLU ILE SER MET ASP
SEQRES 15 R 522 LEU MET THR ASP THR ILE ASP GLY LYS ASP TYR PRO ILE
SEQRES 16 R 522 GLU TRP ILE ILE ILE ASP PRO GLU ALA PHE THR GLU ASN
SEQRES 17 R 522 GLY GLU TRP GLU ILE ILE HIS LYS PRO ALA LYS LYS ASN
SEQRES 18 R 522 ILE TYR GLY ASP LYS PHE PRO ASN GLY THR ASN TYR GLN
SEQRES 19 R 522 ASP VAL THR PHE TYR LEU ILE ILE ARG ARG LYS PRO LEU
SEQRES 20 R 522 PHE TYR VAL ILE ASN PHE ILE THR PRO CYS VAL LEU ILE
SEQRES 21 R 522 SER PHE LEU ALA ALA LEU ALA PHE TYR LEU PRO ALA GLU
SEQRES 22 R 522 SER GLY GLU LYS MET SER THR ALA ILE CYS VAL LEU LEU
SEQRES 23 R 522 ALA GLN ALA VAL PHE LEU LEU LEU THR SER GLN ARG LEU
SEQRES 24 R 522 PRO GLU THR ALA LEU ALA VAL PRO LEU ILE GLY LYS TYR
SEQRES 25 R 522 LEU MET PHE ILE MET SER LEU VAL THR GLY VAL VAL VAL
SEQRES 26 R 522 ASN CYS GLY ILE VAL LEU ASN PHE HIS PHE ARG THR PRO
SEQRES 27 R 522 SER THR HIS VAL LEU SER THR ARG VAL LYS GLN ILE PHE
SEQRES 28 R 522 LEU GLU LYS LEU PRO ARG ILE LEU HIS MET SER ARG VAL
SEQRES 29 R 522 ASP GLU ILE GLU GLN PRO ASP TRP GLN ASN ASP LEU LYS
SEQRES 30 R 522 LEU ARG ARG SER SER SER VAL GLY TYR ILE SER LYS ALA
SEQRES 31 R 522 GLN GLU TYR PHE ASN ILE LYS SER ARG SER GLU LEU MET
SEQRES 32 R 522 PHE GLU LYS GLN SER GLU ARG HIS GLY LEU VAL PRO ARG
SEQRES 33 R 522 VAL THR PRO ARG ILE GLY PHE GLY ASN ASN ASN GLU ASN
SEQRES 34 R 522 ILE ALA ALA SER ASP GLN LEU HIS ASP GLU ILE LYS SER
SEQRES 35 R 522 GLY ILE ASP SER THR ASN TYR ILE VAL LYS GLN ILE LYS
SEQRES 36 R 522 GLU LYS ASN ALA TYR ASP GLU GLU VAL GLY ASN TRP ASN
SEQRES 37 R 522 LEU VAL GLY GLN THR ILE ASP ARG LEU SER MET PHE ILE
SEQRES 38 R 522 ILE THR PRO VAL MET VAL LEU GLY THR ILE PHE ILE PHE
SEQRES 39 R 522 VAL MET GLY ASN PHE ASN ARG PRO PRO ALA LYS PRO PHE
SEQRES 40 R 522 GLU GLY ASP PRO PHE ASP TYR SER SER ASP HIS PRO ARG
SEQRES 41 R 522 CYS ALA
SEQRES 1 S 461 MET ILE LEU CYS SER TYR TRP HIS VAL GLY LEU VAL LEU
SEQRES 2 S 461 LEU LEU PHE SER CYS CYS GLY LEU VAL LEU GLY SER GLU
SEQRES 3 S 461 HIS GLU THR ARG LEU VAL ALA ASN LEU LEU GLU ASN TYR
SEQRES 4 S 461 ASN LYS VAL ILE ARG PRO VAL GLU HIS HIS THR HIS PHE
SEQRES 5 S 461 VAL ASP ILE THR VAL GLY LEU GLN LEU ILE GLN LEU ILE
SEQRES 6 S 461 ASN VAL ASP GLU VAL ASN GLN ILE VAL GLU THR ASN VAL
SEQRES 7 S 461 ARG LEU ARG GLN GLN TRP ILE ASP VAL ARG LEU ARG TRP
SEQRES 8 S 461 ASN PRO ALA ASP TYR GLY GLY ILE LYS LYS ILE ARG LEU
SEQRES 9 S 461 PRO SER ASP ASP VAL TRP LEU PRO ASP LEU VAL LEU TYR
SEQRES 10 S 461 ASN ASN ALA ASP GLY ASP PHE ALA ILE VAL HIS MET THR
SEQRES 11 S 461 LYS LEU LEU LEU ASP TYR THR GLY LYS ILE MET TRP THR
SEQRES 12 S 461 PRO PRO ALA ILE PHE LYS SER TYR CYS GLU ILE ILE VAL
SEQRES 13 S 461 THR HIS PHE PRO PHE ASP GLN GLN ASN CYS THR MET LYS
SEQRES 14 S 461 LEU GLY ILE TRP THR TYR ASP GLY THR LYS VAL SER ILE
SEQRES 15 S 461 SER PRO GLU SER ASP ARG PRO ASP LEU SER THR PHE MET
SEQRES 16 S 461 GLU SER GLY GLU TRP VAL MET LYS ASP TYR ARG GLY TRP
SEQRES 17 S 461 LYS HIS TRP VAL TYR TYR THR CYS CYS PRO ASP THR PRO
SEQRES 18 S 461 TYR LEU ASP ILE THR TYR HIS PHE ILE MET GLN ARG ILE
SEQRES 19 S 461 PRO LEU TYR PHE VAL VAL ASN VAL ILE ILE PRO CYS LEU
SEQRES 20 S 461 LEU PHE SER PHE LEU THR VAL LEU VAL PHE TYR LEU PRO
SEQRES 21 S 461 THR ASP SER GLY GLU LYS MET THR LEU SER ILE SER VAL
SEQRES 22 S 461 LEU LEU SER LEU THR VAL PHE LEU LEU VAL ILE VAL GLU
SEQRES 23 S 461 LEU ILE PRO SER THR SER SER ALA VAL PRO LEU ILE GLY
SEQRES 24 S 461 LYS TYR MET LEU PHE THR MET ILE PHE VAL ILE SER SER
SEQRES 25 S 461 ILE ILE VAL THR VAL VAL VAL ILE ASN THR HIS HIS ARG
SEQRES 26 S 461 SER PRO SER THR HIS THR MET PRO GLN TRP VAL ARG LYS
SEQRES 27 S 461 ILE PHE ILE ASN THR ILE PRO ASN VAL MET PHE PHE SER
SEQRES 28 S 461 THR MET LYS ARG ALA SER LYS GLU LYS GLN GLU ASN LYS
SEQRES 29 S 461 ILE PHE ALA ASP ASP ILE ASP ILE SER ASP ILE SER GLY
SEQRES 30 S 461 LYS GLN VAL THR GLY GLU VAL ILE PHE GLN THR PRO LEU
SEQRES 31 S 461 ILE LYS ASN PRO ASP VAL LYS SER ALA ILE GLU GLY VAL
SEQRES 32 S 461 LYS TYR ILE ALA GLU HIS MET LYS SER ASP GLU GLU SER
SEQRES 33 S 461 SER ASN ALA ALA GLU GLU TRP LYS TYR VAL ALA MET VAL
SEQRES 34 S 461 ILE ASP HIS ILE LEU LEU CYS VAL PHE MET LEU ILE CYS
SEQRES 35 S 461 ILE ILE GLY THR VAL SER VAL PHE ALA GLY ARG LEU ILE
SEQRES 36 S 461 GLU LEU SER GLN GLU GLY
SEQRES 1 T 505 MET VAL LEU THR LEU LEU LEU ILE ILE CYS LEU ALA LEU
SEQRES 2 T 505 GLU VAL ARG SER ASN GLU GLU GLY ARG LEU ILE GLU LYS
SEQRES 3 T 505 LEU LEU GLY ASP TYR ASP LYS ARG ILE LYS PRO ALA LYS
SEQRES 4 T 505 THR LEU ASP HIS VAL ILE ASP VAL THR LEU LYS LEU THR
SEQRES 5 T 505 LEU THR ASN LEU ILE SER LEU ASN GLU LYS GLU GLU ALA
SEQRES 6 T 505 LEU THR THR ASN VAL TRP ILE GLU ILE GLN TRP ASN ASP
SEQRES 7 T 505 TYR ARG LEU SER TRP ASN THR SER GLU TYR GLU GLY ILE
SEQRES 8 T 505 ASP LEU VAL ARG ILE PRO SER GLU LEU LEU TRP LEU PRO
SEQRES 9 T 505 ASP VAL VAL LEU GLU ASN ASN VAL ASP GLY GLN PHE GLU
SEQRES 10 T 505 VAL ALA TYR TYR ALA ASN VAL LEU VAL TYR ASN ASP GLY
SEQRES 11 T 505 SER MET TYR TRP LEU PRO PRO ALA ILE TYR ARG SER THR
SEQRES 12 T 505 CYS PRO ILE ALA VAL THR TYR PHE PRO PHE ASP TRP GLN
SEQRES 13 T 505 ASN CYS SER LEU VAL PHE ARG SER GLN THR TYR ASN ALA
SEQRES 14 T 505 HIS GLU VAL ASN LEU GLN LEU SER ALA GLU GLU GLY GLU
SEQRES 15 T 505 VAL VAL GLU TRP ILE HIS ILE ASP PRO GLU ASP PHE THR
SEQRES 16 T 505 GLU ASN GLY GLU TRP THR ILE ARG HIS ARG PRO ALA LYS
SEQRES 17 T 505 LYS ASN TYR ASN TRP GLN LEU THR LYS ASP ASP ILE ASP
SEQRES 18 T 505 PHE GLN GLU ILE ILE PHE PHE LEU ILE ILE GLN ARG LYS
SEQRES 19 T 505 PRO LEU PHE TYR ILE ILE ASN ILE ILE ALA PRO CYS VAL
SEQRES 20 T 505 LEU ILE SER SER LEU VAL VAL LEU VAL TYR PHE LEU PRO
SEQRES 21 T 505 ALA GLN ALA GLY GLY GLN LYS CYS THR LEU SER ILE SER
SEQRES 22 T 505 VAL LEU LEU ALA GLN THR ILE PHE LEU PHE LEU ILE ALA
SEQRES 23 T 505 GLN LYS VAL PRO GLU THR SER LEU ASN VAL PRO LEU ILE
SEQRES 24 T 505 GLY LYS TYR LEU ILE PHE VAL MET PHE VAL SER LEU VAL
SEQRES 25 T 505 ILE VAL THR ASN CYS VAL ILE VAL LEU ASN VAL SER LEU
SEQRES 26 T 505 ARG THR PRO ASN THR HIS SER LEU SER GLU LYS ILE LYS
SEQRES 27 T 505 HIS LEU PHE LEU GLU PHE LEU PRO LYS TYR LEU GLY MET
SEQRES 28 T 505 HIS LEU GLU PRO SER GLU GLU THR PRO GLU LYS PRO GLN
SEQRES 29 T 505 PRO ARG ARG ARG SER SER PHE GLY ILE MET ILE LYS ALA
SEQRES 30 T 505 GLU GLU TYR ILE LEU LYS LYS PRO ARG SER GLU LEU MET
SEQRES 31 T 505 PHE GLU GLU GLN LYS ASP ARG HIS GLY LEU LYS ARG VAL
SEQRES 32 T 505 ASN LYS MET THR SER ASP ILE ASP ILE GLY THR THR VAL
SEQRES 33 T 505 ASP LEU TYR LYS ASP LEU ALA ASN PHE ALA PRO GLU ILE
SEQRES 34 T 505 LYS SER CYS VAL GLU ALA CYS ASN PHE ILE ALA LYS SER
SEQRES 35 T 505 THR LYS GLU GLN ASN ASP SER GLY SER GLU ASN GLU ASN
SEQRES 36 T 505 TRP VAL LEU ILE GLY LYS VAL ILE ASP LYS ALA CYS PHE
SEQRES 37 T 505 TRP ILE ALA LEU LEU LEU PHE SER LEU GLY THR LEU ALA
SEQRES 38 T 505 ILE PHE LEU THR GLY HIS LEU ASN GLN VAL PRO GLU PHE
SEQRES 39 T 505 PRO PHE PRO GLY ASP PRO ARG LYS TYR VAL PRO
SEQRES 1 U 461 MET ILE LEU CYS SER TYR TRP HIS VAL GLY LEU VAL LEU
SEQRES 2 U 461 LEU LEU PHE SER CYS CYS GLY LEU VAL LEU GLY SER GLU
SEQRES 3 U 461 HIS GLU THR ARG LEU VAL ALA ASN LEU LEU GLU ASN TYR
SEQRES 4 U 461 ASN LYS VAL ILE ARG PRO VAL GLU HIS HIS THR HIS PHE
SEQRES 5 U 461 VAL ASP ILE THR VAL GLY LEU GLN LEU ILE GLN LEU ILE
SEQRES 6 U 461 ASN VAL ASP GLU VAL ASN GLN ILE VAL GLU THR ASN VAL
SEQRES 7 U 461 ARG LEU ARG GLN GLN TRP ILE ASP VAL ARG LEU ARG TRP
SEQRES 8 U 461 ASN PRO ALA ASP TYR GLY GLY ILE LYS LYS ILE ARG LEU
SEQRES 9 U 461 PRO SER ASP ASP VAL TRP LEU PRO ASP LEU VAL LEU TYR
SEQRES 10 U 461 ASN ASN ALA ASP GLY ASP PHE ALA ILE VAL HIS MET THR
SEQRES 11 U 461 LYS LEU LEU LEU ASP TYR THR GLY LYS ILE MET TRP THR
SEQRES 12 U 461 PRO PRO ALA ILE PHE LYS SER TYR CYS GLU ILE ILE VAL
SEQRES 13 U 461 THR HIS PHE PRO PHE ASP GLN GLN ASN CYS THR MET LYS
SEQRES 14 U 461 LEU GLY ILE TRP THR TYR ASP GLY THR LYS VAL SER ILE
SEQRES 15 U 461 SER PRO GLU SER ASP ARG PRO ASP LEU SER THR PHE MET
SEQRES 16 U 461 GLU SER GLY GLU TRP VAL MET LYS ASP TYR ARG GLY TRP
SEQRES 17 U 461 LYS HIS TRP VAL TYR TYR THR CYS CYS PRO ASP THR PRO
SEQRES 18 U 461 TYR LEU ASP ILE THR TYR HIS PHE ILE MET GLN ARG ILE
SEQRES 19 U 461 PRO LEU TYR PHE VAL VAL ASN VAL ILE ILE PRO CYS LEU
SEQRES 20 U 461 LEU PHE SER PHE LEU THR VAL LEU VAL PHE TYR LEU PRO
SEQRES 21 U 461 THR ASP SER GLY GLU LYS MET THR LEU SER ILE SER VAL
SEQRES 22 U 461 LEU LEU SER LEU THR VAL PHE LEU LEU VAL ILE VAL GLU
SEQRES 23 U 461 LEU ILE PRO SER THR SER SER ALA VAL PRO LEU ILE GLY
SEQRES 24 U 461 LYS TYR MET LEU PHE THR MET ILE PHE VAL ILE SER SER
SEQRES 25 U 461 ILE ILE VAL THR VAL VAL VAL ILE ASN THR HIS HIS ARG
SEQRES 26 U 461 SER PRO SER THR HIS THR MET PRO GLN TRP VAL ARG LYS
SEQRES 27 U 461 ILE PHE ILE ASN THR ILE PRO ASN VAL MET PHE PHE SER
SEQRES 28 U 461 THR MET LYS ARG ALA SER LYS GLU LYS GLN GLU ASN LYS
SEQRES 29 U 461 ILE PHE ALA ASP ASP ILE ASP ILE SER ASP ILE SER GLY
SEQRES 30 U 461 LYS GLN VAL THR GLY GLU VAL ILE PHE GLN THR PRO LEU
SEQRES 31 U 461 ILE LYS ASN PRO ASP VAL LYS SER ALA ILE GLU GLY VAL
SEQRES 32 U 461 LYS TYR ILE ALA GLU HIS MET LYS SER ASP GLU GLU SER
SEQRES 33 U 461 SER ASN ALA ALA GLU GLU TRP LYS TYR VAL ALA MET VAL
SEQRES 34 U 461 ILE ASP HIS ILE LEU LEU CYS VAL PHE MET LEU ILE CYS
SEQRES 35 U 461 ILE ILE GLY THR VAL SER VAL PHE ALA GLY ARG LEU ILE
SEQRES 36 U 461 GLU LEU SER GLN GLU GLY
SEQRES 1 V 493 MET GLU ASP VAL ARG ARG MET ALA LEU GLY LEU VAL VAL
SEQRES 2 V 493 MET MET ALA LEU ALA LEU SER GLY VAL GLY ALA SER VAL
SEQRES 3 V 493 MET GLU ASP THR LEU LEU SER VAL LEU PHE GLU ASN TYR
SEQRES 4 V 493 ASN PRO LYS VAL ARG PRO SER GLN THR VAL GLY ASP LYS
SEQRES 5 V 493 VAL THR VAL ARG VAL GLY LEU THR LEU THR SER LEU LEU
SEQRES 6 V 493 ILE LEU ASN GLU LYS ASN GLU GLU MET THR THR SER VAL
SEQRES 7 V 493 PHE LEU ASN LEU ALA TRP THR ASP TYR ARG LEU GLN TRP
SEQRES 8 V 493 ASP PRO ALA ALA TYR GLU GLY ILE LYS ASP LEU SER ILE
SEQRES 9 V 493 PRO SER ASP ASP VAL TRP GLN PRO ASP ILE VAL LEU MET
SEQRES 10 V 493 ASN ASN ASN ASP GLY SER PHE GLU ILE THR LEU HIS VAL
SEQRES 11 V 493 ASN VAL LEU VAL GLN HIS THR GLY ALA VAL SER TRP HIS
SEQRES 12 V 493 PRO SER ALA ILE TYR ARG SER SER CYS THR ILE LYS VAL
SEQRES 13 V 493 MET TYR PHE PRO PHE ASP TRP GLN ASN CYS THR MET VAL
SEQRES 14 V 493 PHE LYS SER TYR THR TYR ASP THR SER GLU VAL ILE LEU
SEQRES 15 V 493 GLN HIS ALA LEU ASP ALA LYS GLY GLU ARG GLU VAL LYS
SEQRES 16 V 493 GLU ILE MET ILE ASN GLN ASP ALA PHE THR GLU ASN GLY
SEQRES 17 V 493 GLN TRP SER ILE GLU HIS LYS PRO SER ARG LYS ASN TRP
SEQRES 18 V 493 ARG SER ASP ASP PRO SER TYR GLU ASP VAL THR PHE TYR
SEQRES 19 V 493 LEU ILE ILE GLN ARG LYS PRO LEU PHE TYR ILE VAL TYR
SEQRES 20 V 493 THR ILE VAL PRO CYS ILE LEU ILE SER ILE LEU ALA ILE
SEQRES 21 V 493 LEU VAL PHE TYR LEU PRO PRO ASP ALA GLY GLU LYS MET
SEQRES 22 V 493 SER LEU SER ILE SER ALA LEU LEU ALA LEU THR VAL PHE
SEQRES 23 V 493 LEU LEU LEU LEU ALA ASP LYS VAL PRO GLU THR SER LEU
SEQRES 24 V 493 SER VAL PRO ILE ILE ILE SER TYR LEU MET PHE ILE MET
SEQRES 25 V 493 ILE LEU VAL ALA PHE SER VAL ILE LEU SER VAL VAL VAL
SEQRES 26 V 493 LEU ASN LEU HIS HIS ARG SER PRO ASN THR HIS THR MET
SEQRES 27 V 493 PRO ASN TRP ILE ARG GLN ILE PHE ILE GLU THR LEU PRO
SEQRES 28 V 493 PRO PHE LEU TRP ILE GLN ARG PRO VAL THR THR PRO SER
SEQRES 29 V 493 PRO ASP SER LYS PRO THR ILE ILE SER ARG ALA ASN ASP
SEQRES 30 V 493 GLU TYR PHE ILE ARG LYS PRO ALA GLY ASP PHE VAL CYS
SEQRES 31 V 493 PRO VAL ASP ASN ALA ARG VAL ALA VAL GLN PRO GLU ARG
SEQRES 32 V 493 LEU PHE SER GLU MET LYS TRP HIS LEU ASN GLY LEU THR
SEQRES 33 V 493 GLN PRO VAL THR LEU PRO GLN ASP LEU LYS GLU ALA VAL
SEQRES 34 V 493 GLU ALA ILE LYS TYR ILE ALA GLU GLN LEU GLU SER ALA
SEQRES 35 V 493 SER GLU PHE ASP ASP LEU LYS LYS ASP TRP GLN TYR VAL
SEQRES 36 V 493 ALA MET VAL ALA ASP ARG LEU PHE LEU TYR ILE PHE ILE
SEQRES 37 V 493 THR MET CYS SER ILE GLY THR PHE SER ILE PHE LEU ASP
SEQRES 38 V 493 ALA SER HIS ASN VAL PRO PRO ASP ASN PRO PHE ALA
SEQRES 1 W 522 MET GLY ASN ILE HIS PHE VAL TYR LEU LEU ILE SER CYS
SEQRES 2 W 522 LEU TYR TYR SER GLY CYS SER GLY VAL ASN GLU GLU GLU
SEQRES 3 W 522 ARG LEU ILE ASN ASP LEU LEU ILE VAL ASN LYS TYR ASN
SEQRES 4 W 522 LYS HIS VAL ARG PRO VAL LYS HIS ASN ASN GLU VAL VAL
SEQRES 5 W 522 ASN ILE ALA LEU SER LEU THR LEU SER ASN LEU ILE SER
SEQRES 6 W 522 LEU LYS GLU THR ASP GLU THR LEU THR THR ASN VAL TRP
SEQRES 7 W 522 MET ASP HIS ALA TRP TYR ASP HIS ARG LEU THR TRP ASN
SEQRES 8 W 522 ALA SER GLU TYR SER ASP ILE SER ILE LEU ARG LEU ARG
SEQRES 9 W 522 PRO GLU LEU ILE TRP ILE PRO ASP ILE VAL LEU GLN ASN
SEQRES 10 W 522 ASN ASN ASP GLY GLN TYR ASN VAL ALA TYR PHE CYS ASN
SEQRES 11 W 522 VAL LEU VAL ARG PRO ASN GLY TYR VAL THR TRP LEU PRO
SEQRES 12 W 522 PRO ALA ILE PHE ARG SER SER CYS PRO ILE ASN VAL LEU
SEQRES 13 W 522 TYR PHE PRO PHE ASP TRP GLN ASN CYS SER LEU LYS PHE
SEQRES 14 W 522 THR ALA LEU ASN TYR ASN ALA ASN GLU ILE SER MET ASP
SEQRES 15 W 522 LEU MET THR ASP THR ILE ASP GLY LYS ASP TYR PRO ILE
SEQRES 16 W 522 GLU TRP ILE ILE ILE ASP PRO GLU ALA PHE THR GLU ASN
SEQRES 17 W 522 GLY GLU TRP GLU ILE ILE HIS LYS PRO ALA LYS LYS ASN
SEQRES 18 W 522 ILE TYR GLY ASP LYS PHE PRO ASN GLY THR ASN TYR GLN
SEQRES 19 W 522 ASP VAL THR PHE TYR LEU ILE ILE ARG ARG LYS PRO LEU
SEQRES 20 W 522 PHE TYR VAL ILE ASN PHE ILE THR PRO CYS VAL LEU ILE
SEQRES 21 W 522 SER PHE LEU ALA ALA LEU ALA PHE TYR LEU PRO ALA GLU
SEQRES 22 W 522 SER GLY GLU LYS MET SER THR ALA ILE CYS VAL LEU LEU
SEQRES 23 W 522 ALA GLN ALA VAL PHE LEU LEU LEU THR SER GLN ARG LEU
SEQRES 24 W 522 PRO GLU THR ALA LEU ALA VAL PRO LEU ILE GLY LYS TYR
SEQRES 25 W 522 LEU MET PHE ILE MET SER LEU VAL THR GLY VAL VAL VAL
SEQRES 26 W 522 ASN CYS GLY ILE VAL LEU ASN PHE HIS PHE ARG THR PRO
SEQRES 27 W 522 SER THR HIS VAL LEU SER THR ARG VAL LYS GLN ILE PHE
SEQRES 28 W 522 LEU GLU LYS LEU PRO ARG ILE LEU HIS MET SER ARG VAL
SEQRES 29 W 522 ASP GLU ILE GLU GLN PRO ASP TRP GLN ASN ASP LEU LYS
SEQRES 30 W 522 LEU ARG ARG SER SER SER VAL GLY TYR ILE SER LYS ALA
SEQRES 31 W 522 GLN GLU TYR PHE ASN ILE LYS SER ARG SER GLU LEU MET
SEQRES 32 W 522 PHE GLU LYS GLN SER GLU ARG HIS GLY LEU VAL PRO ARG
SEQRES 33 W 522 VAL THR PRO ARG ILE GLY PHE GLY ASN ASN ASN GLU ASN
SEQRES 34 W 522 ILE ALA ALA SER ASP GLN LEU HIS ASP GLU ILE LYS SER
SEQRES 35 W 522 GLY ILE ASP SER THR ASN TYR ILE VAL LYS GLN ILE LYS
SEQRES 36 W 522 GLU LYS ASN ALA TYR ASP GLU GLU VAL GLY ASN TRP ASN
SEQRES 37 W 522 LEU VAL GLY GLN THR ILE ASP ARG LEU SER MET PHE ILE
SEQRES 38 W 522 ILE THR PRO VAL MET VAL LEU GLY THR ILE PHE ILE PHE
SEQRES 39 W 522 VAL MET GLY ASN PHE ASN ARG PRO PRO ALA LYS PRO PHE
SEQRES 40 W 522 GLU GLY ASP PRO PHE ASP TYR SER SER ASP HIS PRO ARG
SEQRES 41 W 522 CYS ALA
SEQRES 1 X 461 MET ILE LEU CYS SER TYR TRP HIS VAL GLY LEU VAL LEU
SEQRES 2 X 461 LEU LEU PHE SER CYS CYS GLY LEU VAL LEU GLY SER GLU
SEQRES 3 X 461 HIS GLU THR ARG LEU VAL ALA ASN LEU LEU GLU ASN TYR
SEQRES 4 X 461 ASN LYS VAL ILE ARG PRO VAL GLU HIS HIS THR HIS PHE
SEQRES 5 X 461 VAL ASP ILE THR VAL GLY LEU GLN LEU ILE GLN LEU ILE
SEQRES 6 X 461 ASN VAL ASP GLU VAL ASN GLN ILE VAL GLU THR ASN VAL
SEQRES 7 X 461 ARG LEU ARG GLN GLN TRP ILE ASP VAL ARG LEU ARG TRP
SEQRES 8 X 461 ASN PRO ALA ASP TYR GLY GLY ILE LYS LYS ILE ARG LEU
SEQRES 9 X 461 PRO SER ASP ASP VAL TRP LEU PRO ASP LEU VAL LEU TYR
SEQRES 10 X 461 ASN ASN ALA ASP GLY ASP PHE ALA ILE VAL HIS MET THR
SEQRES 11 X 461 LYS LEU LEU LEU ASP TYR THR GLY LYS ILE MET TRP THR
SEQRES 12 X 461 PRO PRO ALA ILE PHE LYS SER TYR CYS GLU ILE ILE VAL
SEQRES 13 X 461 THR HIS PHE PRO PHE ASP GLN GLN ASN CYS THR MET LYS
SEQRES 14 X 461 LEU GLY ILE TRP THR TYR ASP GLY THR LYS VAL SER ILE
SEQRES 15 X 461 SER PRO GLU SER ASP ARG PRO ASP LEU SER THR PHE MET
SEQRES 16 X 461 GLU SER GLY GLU TRP VAL MET LYS ASP TYR ARG GLY TRP
SEQRES 17 X 461 LYS HIS TRP VAL TYR TYR THR CYS CYS PRO ASP THR PRO
SEQRES 18 X 461 TYR LEU ASP ILE THR TYR HIS PHE ILE MET GLN ARG ILE
SEQRES 19 X 461 PRO LEU TYR PHE VAL VAL ASN VAL ILE ILE PRO CYS LEU
SEQRES 20 X 461 LEU PHE SER PHE LEU THR VAL LEU VAL PHE TYR LEU PRO
SEQRES 21 X 461 THR ASP SER GLY GLU LYS MET THR LEU SER ILE SER VAL
SEQRES 22 X 461 LEU LEU SER LEU THR VAL PHE LEU LEU VAL ILE VAL GLU
SEQRES 23 X 461 LEU ILE PRO SER THR SER SER ALA VAL PRO LEU ILE GLY
SEQRES 24 X 461 LYS TYR MET LEU PHE THR MET ILE PHE VAL ILE SER SER
SEQRES 25 X 461 ILE ILE VAL THR VAL VAL VAL ILE ASN THR HIS HIS ARG
SEQRES 26 X 461 SER PRO SER THR HIS THR MET PRO GLN TRP VAL ARG LYS
SEQRES 27 X 461 ILE PHE ILE ASN THR ILE PRO ASN VAL MET PHE PHE SER
SEQRES 28 X 461 THR MET LYS ARG ALA SER LYS GLU LYS GLN GLU ASN LYS
SEQRES 29 X 461 ILE PHE ALA ASP ASP ILE ASP ILE SER ASP ILE SER GLY
SEQRES 30 X 461 LYS GLN VAL THR GLY GLU VAL ILE PHE GLN THR PRO LEU
SEQRES 31 X 461 ILE LYS ASN PRO ASP VAL LYS SER ALA ILE GLU GLY VAL
SEQRES 32 X 461 LYS TYR ILE ALA GLU HIS MET LYS SER ASP GLU GLU SER
SEQRES 33 X 461 SER ASN ALA ALA GLU GLU TRP LYS TYR VAL ALA MET VAL
SEQRES 34 X 461 ILE ASP HIS ILE LEU LEU CYS VAL PHE MET LEU ILE CYS
SEQRES 35 X 461 ILE ILE GLY THR VAL SER VAL PHE ALA GLY ARG LEU ILE
SEQRES 36 X 461 GLU LEU SER GLN GLU GLY
SEQRES 1 Y 505 MET VAL LEU THR LEU LEU LEU ILE ILE CYS LEU ALA LEU
SEQRES 2 Y 505 GLU VAL ARG SER ASN GLU GLU GLY ARG LEU ILE GLU LYS
SEQRES 3 Y 505 LEU LEU GLY ASP TYR ASP LYS ARG ILE LYS PRO ALA LYS
SEQRES 4 Y 505 THR LEU ASP HIS VAL ILE ASP VAL THR LEU LYS LEU THR
SEQRES 5 Y 505 LEU THR ASN LEU ILE SER LEU ASN GLU LYS GLU GLU ALA
SEQRES 6 Y 505 LEU THR THR ASN VAL TRP ILE GLU ILE GLN TRP ASN ASP
SEQRES 7 Y 505 TYR ARG LEU SER TRP ASN THR SER GLU TYR GLU GLY ILE
SEQRES 8 Y 505 ASP LEU VAL ARG ILE PRO SER GLU LEU LEU TRP LEU PRO
SEQRES 9 Y 505 ASP VAL VAL LEU GLU ASN ASN VAL ASP GLY GLN PHE GLU
SEQRES 10 Y 505 VAL ALA TYR TYR ALA ASN VAL LEU VAL TYR ASN ASP GLY
SEQRES 11 Y 505 SER MET TYR TRP LEU PRO PRO ALA ILE TYR ARG SER THR
SEQRES 12 Y 505 CYS PRO ILE ALA VAL THR TYR PHE PRO PHE ASP TRP GLN
SEQRES 13 Y 505 ASN CYS SER LEU VAL PHE ARG SER GLN THR TYR ASN ALA
SEQRES 14 Y 505 HIS GLU VAL ASN LEU GLN LEU SER ALA GLU GLU GLY GLU
SEQRES 15 Y 505 VAL VAL GLU TRP ILE HIS ILE ASP PRO GLU ASP PHE THR
SEQRES 16 Y 505 GLU ASN GLY GLU TRP THR ILE ARG HIS ARG PRO ALA LYS
SEQRES 17 Y 505 LYS ASN TYR ASN TRP GLN LEU THR LYS ASP ASP ILE ASP
SEQRES 18 Y 505 PHE GLN GLU ILE ILE PHE PHE LEU ILE ILE GLN ARG LYS
SEQRES 19 Y 505 PRO LEU PHE TYR ILE ILE ASN ILE ILE ALA PRO CYS VAL
SEQRES 20 Y 505 LEU ILE SER SER LEU VAL VAL LEU VAL TYR PHE LEU PRO
SEQRES 21 Y 505 ALA GLN ALA GLY GLY GLN LYS CYS THR LEU SER ILE SER
SEQRES 22 Y 505 VAL LEU LEU ALA GLN THR ILE PHE LEU PHE LEU ILE ALA
SEQRES 23 Y 505 GLN LYS VAL PRO GLU THR SER LEU ASN VAL PRO LEU ILE
SEQRES 24 Y 505 GLY LYS TYR LEU ILE PHE VAL MET PHE VAL SER LEU VAL
SEQRES 25 Y 505 ILE VAL THR ASN CYS VAL ILE VAL LEU ASN VAL SER LEU
SEQRES 26 Y 505 ARG THR PRO ASN THR HIS SER LEU SER GLU LYS ILE LYS
SEQRES 27 Y 505 HIS LEU PHE LEU GLU PHE LEU PRO LYS TYR LEU GLY MET
SEQRES 28 Y 505 HIS LEU GLU PRO SER GLU GLU THR PRO GLU LYS PRO GLN
SEQRES 29 Y 505 PRO ARG ARG ARG SER SER PHE GLY ILE MET ILE LYS ALA
SEQRES 30 Y 505 GLU GLU TYR ILE LEU LYS LYS PRO ARG SER GLU LEU MET
SEQRES 31 Y 505 PHE GLU GLU GLN LYS ASP ARG HIS GLY LEU LYS ARG VAL
SEQRES 32 Y 505 ASN LYS MET THR SER ASP ILE ASP ILE GLY THR THR VAL
SEQRES 33 Y 505 ASP LEU TYR LYS ASP LEU ALA ASN PHE ALA PRO GLU ILE
SEQRES 34 Y 505 LYS SER CYS VAL GLU ALA CYS ASN PHE ILE ALA LYS SER
SEQRES 35 Y 505 THR LYS GLU GLN ASN ASP SER GLY SER GLU ASN GLU ASN
SEQRES 36 Y 505 TRP VAL LEU ILE GLY LYS VAL ILE ASP LYS ALA CYS PHE
SEQRES 37 Y 505 TRP ILE ALA LEU LEU LEU PHE SER LEU GLY THR LEU ALA
SEQRES 38 Y 505 ILE PHE LEU THR GLY HIS LEU ASN GLN VAL PRO GLU PHE
SEQRES 39 Y 505 PRO PHE PRO GLY ASP PRO ARG LYS TYR VAL PRO
SEQRES 1 Z 461 MET ILE LEU CYS SER TYR TRP HIS VAL GLY LEU VAL LEU
SEQRES 2 Z 461 LEU LEU PHE SER CYS CYS GLY LEU VAL LEU GLY SER GLU
SEQRES 3 Z 461 HIS GLU THR ARG LEU VAL ALA ASN LEU LEU GLU ASN TYR
SEQRES 4 Z 461 ASN LYS VAL ILE ARG PRO VAL GLU HIS HIS THR HIS PHE
SEQRES 5 Z 461 VAL ASP ILE THR VAL GLY LEU GLN LEU ILE GLN LEU ILE
SEQRES 6 Z 461 ASN VAL ASP GLU VAL ASN GLN ILE VAL GLU THR ASN VAL
SEQRES 7 Z 461 ARG LEU ARG GLN GLN TRP ILE ASP VAL ARG LEU ARG TRP
SEQRES 8 Z 461 ASN PRO ALA ASP TYR GLY GLY ILE LYS LYS ILE ARG LEU
SEQRES 9 Z 461 PRO SER ASP ASP VAL TRP LEU PRO ASP LEU VAL LEU TYR
SEQRES 10 Z 461 ASN ASN ALA ASP GLY ASP PHE ALA ILE VAL HIS MET THR
SEQRES 11 Z 461 LYS LEU LEU LEU ASP TYR THR GLY LYS ILE MET TRP THR
SEQRES 12 Z 461 PRO PRO ALA ILE PHE LYS SER TYR CYS GLU ILE ILE VAL
SEQRES 13 Z 461 THR HIS PHE PRO PHE ASP GLN GLN ASN CYS THR MET LYS
SEQRES 14 Z 461 LEU GLY ILE TRP THR TYR ASP GLY THR LYS VAL SER ILE
SEQRES 15 Z 461 SER PRO GLU SER ASP ARG PRO ASP LEU SER THR PHE MET
SEQRES 16 Z 461 GLU SER GLY GLU TRP VAL MET LYS ASP TYR ARG GLY TRP
SEQRES 17 Z 461 LYS HIS TRP VAL TYR TYR THR CYS CYS PRO ASP THR PRO
SEQRES 18 Z 461 TYR LEU ASP ILE THR TYR HIS PHE ILE MET GLN ARG ILE
SEQRES 19 Z 461 PRO LEU TYR PHE VAL VAL ASN VAL ILE ILE PRO CYS LEU
SEQRES 20 Z 461 LEU PHE SER PHE LEU THR VAL LEU VAL PHE TYR LEU PRO
SEQRES 21 Z 461 THR ASP SER GLY GLU LYS MET THR LEU SER ILE SER VAL
SEQRES 22 Z 461 LEU LEU SER LEU THR VAL PHE LEU LEU VAL ILE VAL GLU
SEQRES 23 Z 461 LEU ILE PRO SER THR SER SER ALA VAL PRO LEU ILE GLY
SEQRES 24 Z 461 LYS TYR MET LEU PHE THR MET ILE PHE VAL ILE SER SER
SEQRES 25 Z 461 ILE ILE VAL THR VAL VAL VAL ILE ASN THR HIS HIS ARG
SEQRES 26 Z 461 SER PRO SER THR HIS THR MET PRO GLN TRP VAL ARG LYS
SEQRES 27 Z 461 ILE PHE ILE ASN THR ILE PRO ASN VAL MET PHE PHE SER
SEQRES 28 Z 461 THR MET LYS ARG ALA SER LYS GLU LYS GLN GLU ASN LYS
SEQRES 29 Z 461 ILE PHE ALA ASP ASP ILE ASP ILE SER ASP ILE SER GLY
SEQRES 30 Z 461 LYS GLN VAL THR GLY GLU VAL ILE PHE GLN THR PRO LEU
SEQRES 31 Z 461 ILE LYS ASN PRO ASP VAL LYS SER ALA ILE GLU GLY VAL
SEQRES 32 Z 461 LYS TYR ILE ALA GLU HIS MET LYS SER ASP GLU GLU SER
SEQRES 33 Z 461 SER ASN ALA ALA GLU GLU TRP LYS TYR VAL ALA MET VAL
SEQRES 34 Z 461 ILE ASP HIS ILE LEU LEU CYS VAL PHE MET LEU ILE CYS
SEQRES 35 Z 461 ILE ILE GLY THR VAL SER VAL PHE ALA GLY ARG LEU ILE
SEQRES 36 Z 461 GLU LEU SER GLN GLU GLY
HELIX 1 1 MET 0 3 TYR 0 15 1 13
HELIX 2 2 TYR 0 220 LEU 0 241 1 22
HELIX 3 3 GLU 0 247 LEU 0 275 1 29
HELIX 4 4 ILE 0 281 ARG 0 307 1 27
HELIX 5 5 GLU 0 403 TYR 0 430 1 28
HELIX 6 6 ALA 0 432 VAL 0 462 1 31
HELIX 7 7 PRO 0 463 ASN 0 466 5 4
HELIX 8 8 GLU 1 3 LEU 1 12 1 10
HELIX 9 9 ARG 1 83 ILE 1 87 5 5
HELIX 10 10 ILE 1 132 TYR 1 136 5 5
HELIX 11 11 ILE 1 179 ALA 1 183 5 5
HELIX 12 12 PHE 1 227 GLY 1 254 1 28
HELIX 13 13 LYS 1 256 ALA 1 284 1 29
HELIX 14 14 ILE 1 288 ARG 1 315 1 28
HELIX 15 15 SER 1 421 VAL 1 449 1 29
HELIX 16 16 THR 1 452 ARG 1 480 1 29
HELIX 17 17 HIS 2 3 ASN 2 14 1 12
HELIX 18 18 ASP 2 62 ARG 2 66 5 5
HELIX 19 19 ASP 2 71 LYS 2 76 1 6
HELIX 20 20 ASP 2 83 VAL 2 85 5 3
HELIX 21 21 ASP 2 166 PHE 2 170 5 5
HELIX 22 22 LEU 2 212 GLY 2 240 1 29
HELIX 23 23 LYS 2 242 VAL 2 271 1 30
HELIX 24 24 ILE 2 274 LYS 2 276 5 3
HELIX 25 25 TYR 2 277 ARG 2 301 1 25
HELIX 26 26 SER 2 374 TYR 2 401 1 28
HELIX 27 27 MET 2 404 GLU 2 436 1 33
HELIX 28 28 GLU 3 2 TYR 3 14 1 13
HELIX 29 29 TYR 3 62 SER 3 65 5 4
HELIX 30 30 PRO 3 80 LEU 3 84 5 5
HELIX 31 31 ILE 3 172 ASP 3 176 5 5
HELIX 32 32 TYR 3 221 ALA 3 246 1 26
HELIX 33 33 GLY 3 247 GLN 3 249 5 3
HELIX 34 34 LYS 3 250 VAL 3 279 1 30
HELIX 35 35 GLY 3 283 SER 3 307 1 25
HELIX 36 36 SER 3 414 ILE 3 442 1 29
HELIX 37 37 GLY 3 443 VAL 3 474 1 32
HELIX 38 38 HIS A 3 ASN A 14 1 12
HELIX 39 39 ASP A 71 LYS A 76 1 6
HELIX 40 40 ASP A 83 VAL A 85 5 3
HELIX 41 41 LEU A 212 SER A 239 1 28
HELIX 42 42 LYS A 242 VAL A 271 1 30
HELIX 43 43 ILE A 274 LYS A 276 5 3
HELIX 44 44 TYR A 277 ARG A 301 1 25
HELIX 45 45 SER A 374 TRP A 399 1 26
HELIX 46 46 VAL A 405 GLU A 436 1 32
HELIX 47 47 MET B 3 TYR B 15 1 13
HELIX 48 48 TYR B 220 LEU B 241 1 22
HELIX 49 49 GLU B 247 LEU B 275 1 29
HELIX 50 50 ILE B 281 ARG B 307 1 27
HELIX 51 51 GLU B 403 TYR B 430 1 28
HELIX 52 52 ALA B 432 VAL B 462 1 31
HELIX 53 53 PRO B 463 ASN B 466 5 4
HELIX 54 54 GLU C 3 LEU C 12 1 10
HELIX 55 55 ARG C 83 ILE C 87 5 5
HELIX 56 56 ILE C 132 TYR C 136 5 5
HELIX 57 57 ILE C 179 ALA C 183 5 5
HELIX 58 58 PHE C 227 GLY C 254 1 28
HELIX 59 59 LYS C 256 ALA C 284 1 29
HELIX 60 60 ILE C 288 ARG C 315 1 28
HELIX 61 61 SER C 421 VAL C 449 1 29
HELIX 62 62 THR C 452 ARG C 480 1 29
HELIX 63 63 HIS D 3 ASN D 14 1 12
HELIX 64 64 ASP D 62 ARG D 66 5 5
HELIX 65 65 ASP D 71 LYS D 76 1 6
HELIX 66 66 ASP D 83 VAL D 85 5 3
HELIX 67 67 ASP D 166 PHE D 170 5 5
HELIX 68 68 LEU D 212 GLY D 240 1 29
HELIX 69 69 LYS D 242 VAL D 271 1 30
HELIX 70 70 ILE D 274 LYS D 276 5 3
HELIX 71 71 TYR D 277 ARG D 301 1 25
HELIX 72 72 SER D 374 TYR D 401 1 28
HELIX 73 73 MET D 404 GLU D 436 1 33
HELIX 74 74 GLU E 2 TYR E 14 1 13
HELIX 75 75 TYR E 62 SER E 65 5 4
HELIX 76 76 PRO E 80 LEU E 84 5 5
HELIX 77 77 ILE E 172 ASP E 176 5 5
HELIX 78 78 TYR E 221 ALA E 246 1 26
HELIX 79 79 GLY E 247 GLN E 249 5 3
HELIX 80 80 LYS E 250 VAL E 279 1 30
HELIX 81 81 GLY E 283 SER E 307 1 25
HELIX 82 82 SER E 414 ILE E 442 1 29
HELIX 83 83 GLY E 443 VAL E 474 1 32
HELIX 84 84 HIS F 3 ASN F 14 1 12
HELIX 85 85 ASP F 71 LYS F 76 1 6
HELIX 86 86 ASP F 83 VAL F 85 5 3
HELIX 87 87 LEU F 212 SER F 239 1 28
HELIX 88 88 LYS F 242 VAL F 271 1 30
HELIX 89 89 ILE F 274 LYS F 276 5 3
HELIX 90 90 TYR F 277 ARG F 301 1 25
HELIX 91 91 SER F 374 TRP F 399 1 26
HELIX 92 92 VAL F 405 GLU F 436 1 32
HELIX 93 93 MET G 3 TYR G 15 1 13
HELIX 94 94 TYR G 220 LEU G 241 1 22
HELIX 95 95 GLU G 247 LEU G 275 1 29
HELIX 96 96 ILE G 281 ARG G 307 1 27
HELIX 97 97 GLU G 403 TYR G 430 1 28
HELIX 98 98 ALA G 432 VAL G 462 1 31
HELIX 99 99 PRO G 463 ASN G 466 5 4
HELIX 100 100 GLU H 3 LEU H 12 1 10
HELIX 101 101 ARG H 83 ILE H 87 5 5
HELIX 102 102 ILE H 132 TYR H 136 5 5
HELIX 103 103 ILE H 179 ALA H 183 5 5
HELIX 104 104 PHE H 227 GLY H 254 1 28
HELIX 105 105 LYS H 256 ALA H 284 1 29
HELIX 106 106 ILE H 288 ARG H 315 1 28
HELIX 107 107 SER H 421 VAL H 449 1 29
HELIX 108 108 THR H 452 ARG H 480 1 29
HELIX 109 109 HIS I 3 ASN I 14 1 12
HELIX 110 110 ASP I 62 ARG I 66 5 5
HELIX 111 111 ASP I 71 LYS I 76 1 6
HELIX 112 112 ASP I 83 VAL I 85 5 3
HELIX 113 113 ASP I 166 PHE I 170 5 5
HELIX 114 114 LEU I 212 GLY I 240 1 29
HELIX 115 115 LYS I 242 VAL I 271 1 30
HELIX 116 116 ILE I 274 LYS I 276 5 3
HELIX 117 117 TYR I 277 ARG I 301 1 25
HELIX 118 118 SER I 374 TYR I 401 1 28
HELIX 119 119 MET I 404 GLU I 436 1 33
HELIX 120 120 GLU J 2 TYR J 14 1 13
HELIX 121 121 TYR J 62 SER J 65 5 4
HELIX 122 122 PRO J 80 LEU J 84 5 5
HELIX 123 123 ILE J 172 ASP J 176 5 5
HELIX 124 124 TYR J 221 ALA J 246 1 26
HELIX 125 125 GLY J 247 GLN J 249 5 3
HELIX 126 126 LYS J 250 VAL J 279 1 30
HELIX 127 127 GLY J 283 SER J 307 1 25
HELIX 128 128 SER J 414 ILE J 442 1 29
HELIX 129 129 GLY J 443 VAL J 474 1 32
HELIX 130 130 HIS K 3 ASN K 14 1 12
HELIX 131 131 ASP K 71 LYS K 76 1 6
HELIX 132 132 ASP K 83 VAL K 85 5 3
HELIX 133 133 LEU K 212 SER K 239 1 28
HELIX 134 134 LYS K 242 VAL K 271 1 30
HELIX 135 135 ILE K 274 LYS K 276 5 3
HELIX 136 136 TYR K 277 ARG K 301 1 25
HELIX 137 137 SER K 374 TRP K 399 1 26
HELIX 138 138 VAL K 405 GLU K 436 1 32
HELIX 139 139 MET L 3 TYR L 15 1 13
HELIX 140 140 TYR L 220 LEU L 241 1 22
HELIX 141 141 GLU L 247 LEU L 275 1 29
HELIX 142 142 ILE L 281 ARG L 307 1 27
HELIX 143 143 GLU L 403 TYR L 430 1 28
HELIX 144 144 ALA L 432 VAL L 462 1 31
HELIX 145 145 PRO L 463 ASN L 466 5 4
HELIX 146 146 GLU M 3 LEU M 12 1 10
HELIX 147 147 ARG M 83 ILE M 87 5 5
HELIX 148 148 ILE M 132 TYR M 136 5 5
HELIX 149 149 ILE M 179 ALA M 183 5 5
HELIX 150 150 PHE M 227 GLY M 254 1 28
HELIX 151 151 LYS M 256 ALA M 284 1 29
HELIX 152 152 ILE M 288 ARG M 315 1 28
HELIX 153 153 SER M 421 VAL M 449 1 29
HELIX 154 154 THR M 452 ARG M 480 1 29
HELIX 155 155 HIS N 3 ASN N 14 1 12
HELIX 156 156 ASP N 62 ARG N 66 5 5
HELIX 157 157 ASP N 71 LYS N 76 1 6
HELIX 158 158 ASP N 83 VAL N 85 5 3
HELIX 159 159 ASP N 166 PHE N 170 5 5
HELIX 160 160 LEU N 212 GLY N 240 1 29
HELIX 161 161 LYS N 242 VAL N 271 1 30
HELIX 162 162 ILE N 274 LYS N 276 5 3
HELIX 163 163 TYR N 277 ARG N 301 1 25
HELIX 164 164 SER N 374 TYR N 401 1 28
HELIX 165 165 MET N 404 GLU N 436 1 33
HELIX 166 166 GLU O 2 TYR O 14 1 13
HELIX 167 167 TYR O 62 SER O 65 5 4
HELIX 168 168 PRO O 80 LEU O 84 5 5
HELIX 169 169 ILE O 172 ASP O 176 5 5
HELIX 170 170 TYR O 221 ALA O 246 1 26
HELIX 171 171 GLY O 247 GLN O 249 5 3
HELIX 172 172 LYS O 250 VAL O 279 1 30
HELIX 173 173 GLY O 283 SER O 307 1 25
HELIX 174 174 SER O 414 ILE O 442 1 29
HELIX 175 175 GLY O 443 VAL O 474 1 32
HELIX 176 176 HIS P 3 ASN P 14 1 12
HELIX 177 177 ASP P 71 LYS P 76 1 6
HELIX 178 178 ASP P 83 VAL P 85 5 3
HELIX 179 179 LEU P 212 SER P 239 1 28
HELIX 180 180 LYS P 242 VAL P 271 1 30
HELIX 181 181 ILE P 274 LYS P 276 5 3
HELIX 182 182 TYR P 277 ARG P 301 1 25
HELIX 183 183 SER P 374 TRP P 399 1 26
HELIX 184 184 VAL P 405 GLU P 436 1 32
HELIX 185 185 MET Q 3 TYR Q 15 1 13
HELIX 186 186 TYR Q 220 LEU Q 241 1 22
HELIX 187 187 GLU Q 247 LEU Q 275 1 29
HELIX 188 188 ILE Q 281 ARG Q 307 1 27
HELIX 189 189 GLU Q 403 TYR Q 430 1 28
HELIX 190 190 ALA Q 432 VAL Q 462 1 31
HELIX 191 191 PRO Q 463 ASN Q 466 5 4
HELIX 192 192 GLU R 3 LEU R 12 1 10
HELIX 193 193 ARG R 83 ILE R 87 5 5
HELIX 194 194 ILE R 132 TYR R 136 5 5
HELIX 195 195 ILE R 179 ALA R 183 5 5
HELIX 196 196 PHE R 227 GLY R 254 1 28
HELIX 197 197 LYS R 256 ALA R 284 1 29
HELIX 198 198 ILE R 288 ARG R 315 1 28
HELIX 199 199 SER R 421 VAL R 449 1 29
HELIX 200 200 THR R 452 ARG R 480 1 29
HELIX 201 201 HIS S 3 ASN S 14 1 12
HELIX 202 202 ASP S 62 ARG S 66 5 5
HELIX 203 203 ASP S 71 LYS S 76 1 6
HELIX 204 204 ASP S 83 VAL S 85 5 3
HELIX 205 205 ASP S 166 PHE S 170 5 5
HELIX 206 206 LEU S 212 GLY S 240 1 29
HELIX 207 207 LYS S 242 VAL S 271 1 30
HELIX 208 208 ILE S 274 LYS S 276 5 3
HELIX 209 209 TYR S 277 ARG S 301 1 25
HELIX 210 210 SER S 374 TYR S 401 1 28
HELIX 211 211 MET S 404 GLU S 436 1 33
HELIX 212 212 GLU T 2 TYR T 14 1 13
HELIX 213 213 TYR T 62 SER T 65 5 4
HELIX 214 214 PRO T 80 LEU T 84 5 5
HELIX 215 215 ILE T 172 ASP T 176 5 5
HELIX 216 216 TYR T 221 ALA T 246 1 26
HELIX 217 217 GLY T 247 GLN T 249 5 3
HELIX 218 218 LYS T 250 VAL T 279 1 30
HELIX 219 219 GLY T 283 SER T 307 1 25
HELIX 220 220 SER T 414 ILE T 442 1 29
HELIX 221 221 GLY T 443 VAL T 474 1 32
HELIX 222 222 HIS U 3 ASN U 14 1 12
HELIX 223 223 ASP U 71 LYS U 76 1 6
HELIX 224 224 ASP U 83 VAL U 85 5 3
HELIX 225 225 LEU U 212 SER U 239 1 28
HELIX 226 226 LYS U 242 VAL U 271 1 30
HELIX 227 227 ILE U 274 LYS U 276 5 3
HELIX 228 228 TYR U 277 ARG U 301 1 25
HELIX 229 229 SER U 374 TRP U 399 1 26
HELIX 230 230 VAL U 405 GLU U 436 1 32
HELIX 231 231 MET V 3 TYR V 15 1 13
HELIX 232 232 TYR V 220 LEU V 241 1 22
HELIX 233 233 GLU V 247 LEU V 275 1 29
HELIX 234 234 ILE V 281 ARG V 307 1 27
HELIX 235 235 GLU V 403 TYR V 430 1 28
HELIX 236 236 ALA V 432 VAL V 462 1 31
HELIX 237 237 PRO V 463 ASN V 466 5 4
HELIX 238 238 GLU W 3 LEU W 12 1 10
HELIX 239 239 ARG W 83 ILE W 87 5 5
HELIX 240 240 ILE W 132 TYR W 136 5 5
HELIX 241 241 ILE W 179 ALA W 183 5 5
HELIX 242 242 PHE W 227 GLY W 254 1 28
HELIX 243 243 LYS W 256 ALA W 284 1 29
HELIX 244 244 ILE W 288 ARG W 315 1 28
HELIX 245 245 SER W 421 VAL W 449 1 29
HELIX 246 246 THR W 452 ARG W 480 1 29
HELIX 247 247 HIS X 3 ASN X 14 1 12
HELIX 248 248 ASP X 62 ARG X 66 5 5
HELIX 249 249 ASP X 71 LYS X 76 1 6
HELIX 250 250 ASP X 83 VAL X 85 5 3
HELIX 251 251 ASP X 166 PHE X 170 5 5
HELIX 252 252 LEU X 212 GLY X 240 1 29
HELIX 253 253 LYS X 242 VAL X 271 1 30
HELIX 254 254 ILE X 274 LYS X 276 5 3
HELIX 255 255 TYR X 277 ARG X 301 1 25
HELIX 256 256 SER X 374 TYR X 401 1 28
HELIX 257 257 MET X 404 GLU X 436 1 33
HELIX 258 258 GLU Y 2 TYR Y 14 1 13
HELIX 259 259 TYR Y 62 SER Y 65 5 4
HELIX 260 260 PRO Y 80 LEU Y 84 5 5
HELIX 261 261 ILE Y 172 ASP Y 176 5 5
HELIX 262 262 TYR Y 221 ALA Y 246 1 26
HELIX 263 263 GLY Y 247 GLN Y 249 5 3
HELIX 264 264 LYS Y 250 VAL Y 279 1 30
HELIX 265 265 GLY Y 283 SER Y 307 1 25
HELIX 266 266 SER Y 414 ILE Y 442 1 29
HELIX 267 267 GLY Y 443 VAL Y 474 1 32
HELIX 268 268 HIS Z 3 ASN Z 14 1 12
HELIX 269 269 ASP Z 71 LYS Z 76 1 6
HELIX 270 270 ASP Z 83 VAL Z 85 5 3
HELIX 271 271 LEU Z 212 SER Z 239 1 28
HELIX 272 272 LYS Z 242 VAL Z 271 1 30
HELIX 273 273 ILE Z 274 LYS Z 276 5 3
HELIX 274 274 TYR Z 277 ARG Z 301 1 25
HELIX 275 275 SER Z 374 TRP Z 399 1 26
HELIX 276 276 VAL Z 405 GLU Z 436 1 32
SHEET 1 0A 6 ASP 0 77 PRO 0 81 0
SHEET 2 0A 6 ASN 0 107 GLN 0 111 -1 O VAL 0 108 N ILE 0 80
SHEET 3 0A 6 ALA 0 115 TRP 0 118 -1 O ALA 0 115 N GLN 0 111
SHEET 4 0A 6 ASN 0 57 THR 0 61 -1 O LEU 0 58 N TRP 0 118
SHEET 5 0A 6 THR 0 30 GLY 0 34 -1 O ARG 0 32 N ALA 0 59
SHEET 6 0A 6 ILE 0 157 GLN 0 159 1 O ILE 0 157 N VAL 0 31
SHEET 1 0B 4 LEU 0 37 ASN 0 44 0
SHEET 2 0B 4 GLU 0 49 PHE 0 55 -1 O GLU 0 49 N ASN 0 44
SHEET 3 0B 4 SER 0 121 SER 0 126 -1 O ALA 0 122 N VAL 0 54
SHEET 4 0B 4 PHE 0 100 GLU 0 101 -1 O GLU 0 101 N ILE 0 123
SHEET 1 0C 4 ILE 0 90 LEU 0 92 0
SHEET 2 0C 4 THR 0 143 SER 0 148 -1 O LYS 0 147 N VAL 0 91
SHEET 3 0C 4 VAL 0 207 TYR 0 210 -1 O VAL 0 207 N PHE 0 146
SHEET 4 0C 4 SER 0 193 LYS 0 195 -1 O ARG 0 194 N THR 0 208
SHEET 1 0D 2 SER 0 187 ILE 0 188 0
SHEET 2 0D 2 ILE 0 213 GLN 0 214 -1 O GLN 0 214 N SER 0 187
SHEET 1 1A 5 LEU 1 80 LEU 1 82 0
SHEET 2 1A 5 VAL 1 110 VAL 1 112 -1 O VAL 1 110 N LEU 1 82
SHEET 3 1A 5 TYR 1 117 TRP 1 120 -1 O THR 1 119 N LEU 1 111
SHEET 4 1A 5 THR 1 51 TYR 1 63 -1 O HIS 1 60 N TRP 1 120
SHEET 5 1A 5 PRO 1 123 SER 1 128 -1 O ALA 1 124 N VAL 1 56
SHEET 1 1B 6 LEU 1 80 LEU 1 82 0
SHEET 2 1B 6 VAL 1 110 VAL 1 112 -1 O VAL 1 110 N LEU 1 82
SHEET 3 1B 6 TYR 1 117 TRP 1 120 -1 O THR 1 119 N LEU 1 111
SHEET 4 1B 6 THR 1 51 TYR 1 63 -1 O HIS 1 60 N TRP 1 120
SHEET 5 1B 6 ASN 1 32 LYS 1 46 -1 O ALA 1 34 N ALA 1 61
SHEET 6 1B 6 SER 1 159 ASP 1 161 1 O SER 1 159 N ILE 1 33
SHEET 1 1C 2 PRO 1 123 SER 1 128 0
SHEET 2 1C 2 THR 1 51 TYR 1 63 -1 O LEU 1 52 N SER 1 128
SHEET 1 1D 4 ILE 1 92 LEU 1 94 0
SHEET 2 1D 4 ASN 1 143 ALA 1 150 -1 O THR 1 149 N VAL 1 93
SHEET 3 1D 4 GLN 1 213 ARG 1 223 -1 O VAL 1 215 N PHE 1 148
SHEET 4 1D 4 ALA 1 197 ILE 1 201 1 O LYS 1 198 N THR 1 216
SHEET 1 1E 4 ILE 1 92 LEU 1 94 0
SHEET 2 1E 4 ASN 1 143 ALA 1 150 -1 O THR 1 149 N VAL 1 93
SHEET 3 1E 4 GLN 1 213 ARG 1 223 -1 O VAL 1 215 N PHE 1 148
SHEET 4 1E 4 TRP 1 190 HIS 1 194 -1 O GLU 1 191 N ARG 1 222
SHEET 1 1F 2 ALA 1 197 ILE 1 201 0
SHEET 2 1F 2 GLN 1 213 ARG 1 223 1 O ASP 1 214 N ASN 1 200
SHEET 1 2A 2 ASP 2 30 THR 2 32 0
SHEET 2 2A 2 SER 2 157 SER 2 159 1 O SER 2 157 N ILE 2 31
SHEET 1 2B 3 LEU 2 37 ASP 2 44 0
SHEET 2 2B 3 ILE 2 49 ARG 2 55 -1 O ILE 2 49 N ASP 2 44
SHEET 3 2B 3 PRO 2 121 TYR 2 127 -1 O ALA 2 122 N VAL 2 54
SHEET 1 2C 2 GLN 2 58 TRP 2 60 0
SHEET 2 2C 2 ILE 2 116 TRP 2 118 -1 O ILE 2 116 N TRP 2 60
SHEET 1 2D 2 ILE 2 78 PRO 2 81 0
SHEET 2 2D 2 LYS 2 107 LEU 2 110 -1 O LEU 2 108 N LEU 2 80
SHEET 1 2E 4 LEU 2 90 LEU 2 92 0
SHEET 2 2E 4 GLN 2 140 ILE 2 148 -1 O GLY 2 147 N VAL 2 91
SHEET 3 2E 4 LEU 2 199 GLN 2 208 -1 O ILE 2 201 N LEU 2 146
SHEET 4 2E 4 VAL 2 177 TRP 2 187 -1 O VAL 2 177 N GLN 2 208
SHEET 1 3A 4 LEU 3 108 VAL 3 109 0
SHEET 2 3A 4 SER 3 114 TRP 3 117 -1 O TYR 3 116 N LEU 3 108
SHEET 3 3A 4 ALA 3 48 ASN 3 60 1 O ILE 3 57 N TRP 3 117
SHEET 4 3A 4 PRO 3 120 SER 3 125 -1 O ALA 3 121 N VAL 3 53
SHEET 1 3B 5 LEU 3 108 VAL 3 109 0
SHEET 2 3B 5 SER 3 114 TRP 3 117 -1 O TYR 3 116 N LEU 3 108
SHEET 3 3B 5 ALA 3 48 ASN 3 60 1 O ILE 3 57 N TRP 3 117
SHEET 4 3B 5 VAL 3 30 ASN 3 43 -1 O THR 3 31 N GLN 3 58
SHEET 5 3B 5 LEU 3 157 GLN 3 158 1 O GLN 3 158 N LEU 3 32
SHEET 1 3C 2 PRO 3 120 SER 3 125 0
SHEET 2 3C 2 ALA 3 48 ASN 3 60 -1 O LEU 3 49 N SER 3 125
SHEET 1 3D 4 VAL 3 89 LEU 3 91 0
SHEET 2 3D 4 LEU 3 143 SER 3 147 -1 O ARG 3 146 N VAL 3 90
SHEET 3 3D 4 GLU 3 207 PHE 3 210 -1 O ILE 3 208 N PHE 3 145
SHEET 4 3D 4 LYS 3 192 ASN 3 193 -1 O ASN 3 193 N GLU 3 207
SHEET 1 3E 2 TRP 3 183 HIS 3 187 0
SHEET 2 3E 2 ILE 3 213 ARG 3 216 -1 O ILE 3 213 N ARG 3 186
SHEET 1 AA 6 ILE A 78 PRO A 81 0
SHEET 2 AA 6 LYS A 107 LEU A 110 -1 O LEU A 108 N LEU A 80
SHEET 3 AA 6 ILE A 116 TRP A 118 -1 O MET A 117 N LEU A 109
SHEET 4 AA 6 ILE A 49 TRP A 60 -1 O GLN A 58 N TRP A 118
SHEET 5 AA 6 PRO A 121 TYR A 127 1 O ALA A 122 N VAL A 54
SHEET 6 AA 6 PHE A 100 ALA A 101 1 O ALA A 101 N ILE A 123
SHEET 1 AB 6 ILE A 78 PRO A 81 0
SHEET 2 AB 6 LYS A 107 LEU A 110 -1 O LEU A 108 N LEU A 80
SHEET 3 AB 6 ILE A 116 TRP A 118 -1 O MET A 117 N LEU A 109
SHEET 4 AB 6 ILE A 49 TRP A 60 -1 O GLN A 58 N TRP A 118
SHEET 5 AB 6 VAL A 29 ASP A 44 -1 O THR A 32 N GLN A 59
SHEET 6 AB 6 VAL A 156 SER A 159 1 O SER A 157 N ILE A 31
SHEET 1 AC 4 LEU A 90 LEU A 92 0
SHEET 2 AC 4 GLN A 140 ILE A 148 -1 O GLY A 147 N VAL A 91
SHEET 3 AC 4 LEU A 199 GLN A 208 -1 O ILE A 201 N LEU A 146
SHEET 4 AC 4 VAL A 177 TRP A 187 -1 O VAL A 177 N GLN A 208
SHEET 1 BA 6 ASP B 77 PRO B 81 0
SHEET 2 BA 6 ASN B 107 GLN B 111 -1 O VAL B 108 N ILE B 80
SHEET 3 BA 6 ALA B 115 TRP B 118 -1 O ALA B 115 N GLN B 111
SHEET 4 BA 6 ASN B 57 THR B 61 -1 O LEU B 58 N TRP B 118
SHEET 5 BA 6 THR B 30 GLY B 34 -1 O ARG B 32 N ALA B 59
SHEET 6 BA 6 ILE B 157 GLN B 159 1 O ILE B 157 N VAL B 31
SHEET 1 BB 4 LEU B 37 ASN B 44 0
SHEET 2 BB 4 GLU B 49 PHE B 55 -1 O GLU B 49 N ASN B 44
SHEET 3 BB 4 SER B 121 SER B 126 -1 O ALA B 122 N VAL B 54
SHEET 4 BB 4 PHE B 100 GLU B 101 -1 O GLU B 101 N ILE B 123
SHEET 1 BC 4 ILE B 90 LEU B 92 0
SHEET 2 BC 4 THR B 143 SER B 148 -1 O LYS B 147 N VAL B 91
SHEET 3 BC 4 VAL B 207 TYR B 210 -1 O VAL B 207 N PHE B 146
SHEET 4 BC 4 SER B 193 LYS B 195 -1 O ARG B 194 N THR B 208
SHEET 1 BD 2 SER B 187 ILE B 188 0
SHEET 2 BD 2 ILE B 213 GLN B 214 -1 O GLN B 214 N SER B 187
SHEET 1 CA 5 LEU C 80 LEU C 82 0
SHEET 2 CA 5 VAL C 110 VAL C 112 -1 O VAL C 110 N LEU C 82
SHEET 3 CA 5 TYR C 117 TRP C 120 -1 O THR C 119 N LEU C 111
SHEET 4 CA 5 THR C 51 TYR C 63 -1 O HIS C 60 N TRP C 120
SHEET 5 CA 5 PRO C 123 SER C 128 -1 O ALA C 124 N VAL C 56
SHEET 1 CB 6 LEU C 80 LEU C 82 0
SHEET 2 CB 6 VAL C 110 VAL C 112 -1 O VAL C 110 N LEU C 82
SHEET 3 CB 6 TYR C 117 TRP C 120 -1 O THR C 119 N LEU C 111
SHEET 4 CB 6 THR C 51 TYR C 63 -1 O HIS C 60 N TRP C 120
SHEET 5 CB 6 ASN C 32 LYS C 46 1 O ALA C 34 N ALA C 61
SHEET 6 CB 6 SER C 159 ASP C 161 1 O SER C 159 N ILE C 33
SHEET 1 CC 2 PRO C 123 SER C 128 0
SHEET 2 CC 2 THR C 51 TYR C 63 -1 O LEU C 52 N SER C 128
SHEET 1 CD 4 ILE C 92 LEU C 94 0
SHEET 2 CD 4 ASN C 143 ALA C 150 -1 O THR C 149 N VAL C 93
SHEET 3 CD 4 GLN C 213 ARG C 223 -1 O VAL C 215 N PHE C 148
SHEET 4 CD 4 ALA C 197 ILE C 201 1 O LYS C 198 N THR C 216
SHEET 1 CE 4 ILE C 92 LEU C 94 0
SHEET 2 CE 4 ASN C 143 ALA C 150 -1 O THR C 149 N VAL C 93
SHEET 3 CE 4 GLN C 213 ARG C 223 -1 O VAL C 215 N PHE C 148
SHEET 4 CE 4 TRP C 190 HIS C 194 -1 O GLU C 191 N ARG C 222
SHEET 1 CF 2 ALA C 197 ILE C 201 0
SHEET 2 CF 2 GLN C 213 ARG C 223 1 O ASP C 214 N ASN C 200
SHEET 1 DA 2 ASP D 30 THR D 32 0
SHEET 2 DA 2 SER D 157 SER D 159 1 O SER D 157 N ILE D 31
SHEET 1 DB 3 LEU D 37 ASP D 44 0
SHEET 2 DB 3 ILE D 49 ARG D 55 -1 O ILE D 49 N ASP D 44
SHEET 3 DB 3 PRO D 121 TYR D 127 -1 O ALA D 122 N VAL D 54
SHEET 1 DC 2 GLN D 58 TRP D 60 0
SHEET 2 DC 2 ILE D 116 TRP D 118 -1 O ILE D 116 N TRP D 60
SHEET 1 DD 2 ILE D 78 PRO D 81 0
SHEET 2 DD 2 LYS D 107 LEU D 110 -1 O LEU D 108 N LEU D 80
SHEET 1 DE 4 LEU D 90 LEU D 92 0
SHEET 2 DE 4 GLN D 140 ILE D 148 -1 O GLY D 147 N VAL D 91
SHEET 3 DE 4 LEU D 199 GLN D 208 -1 O ILE D 201 N LEU D 146
SHEET 4 DE 4 VAL D 177 TRP D 187 -1 O VAL D 177 N GLN D 208
SHEET 1 EA 4 LEU E 108 VAL E 109 0
SHEET 2 EA 4 SER E 114 TRP E 117 -1 O TYR E 116 N LEU E 108
SHEET 3 EA 4 ALA E 48 ASN E 60 1 O ILE E 57 N TRP E 117
SHEET 4 EA 4 PRO E 120 SER E 125 -1 O ALA E 121 N VAL E 53
SHEET 1 EB 5 LEU E 108 VAL E 109 0
SHEET 2 EB 5 SER E 114 TRP E 117 -1 O TYR E 116 N LEU E 108
SHEET 3 EB 5 ALA E 48 ASN E 60 1 O ILE E 57 N TRP E 117
SHEET 4 EB 5 VAL E 30 ASN E 43 -1 O THR E 31 N GLN E 58
SHEET 5 EB 5 LEU E 157 GLN E 158 1 O GLN E 158 N LEU E 32
SHEET 1 EC 2 PRO E 120 SER E 125 0
SHEET 2 EC 2 ALA E 48 ASN E 60 -1 O LEU E 49 N SER E 125
SHEET 1 ED 4 VAL E 89 LEU E 91 0
SHEET 2 ED 4 LEU E 143 SER E 147 -1 O ARG E 146 N VAL E 90
SHEET 3 ED 4 GLU E 207 PHE E 210 -1 O ILE E 208 N PHE E 145
SHEET 4 ED 4 LYS E 192 ASN E 193 -1 O ASN E 193 N GLU E 207
SHEET 1 EE 2 TRP E 183 HIS E 187 0
SHEET 2 EE 2 ILE E 213 ARG E 216 -1 O ILE E 213 N ARG E 186
SHEET 1 FA 6 ILE F 78 PRO F 81 0
SHEET 2 FA 6 LYS F 107 LEU F 110 -1 O LEU F 108 N LEU F 80
SHEET 3 FA 6 ILE F 116 TRP F 118 -1 O MET F 117 N LEU F 109
SHEET 4 FA 6 ILE F 49 TRP F 60 -1 O GLN F 58 N TRP F 118
SHEET 5 FA 6 PRO F 121 TYR F 127 1 O ALA F 122 N VAL F 54
SHEET 6 FA 6 PHE F 100 ALA F 101 1 O ALA F 101 N ILE F 123
SHEET 1 FB 6 ILE F 78 PRO F 81 0
SHEET 2 FB 6 LYS F 107 LEU F 110 -1 O LEU F 108 N LEU F 80
SHEET 3 FB 6 ILE F 116 TRP F 118 -1 O MET F 117 N LEU F 109
SHEET 4 FB 6 ILE F 49 TRP F 60 -1 O GLN F 58 N TRP F 118
SHEET 5 FB 6 VAL F 29 ASP F 44 -1 O THR F 32 N GLN F 59
SHEET 6 FB 6 VAL F 156 SER F 159 1 O SER F 157 N ILE F 31
SHEET 1 FC 4 LEU F 90 LEU F 92 0
SHEET 2 FC 4 GLN F 140 ILE F 148 -1 O GLY F 147 N VAL F 91
SHEET 3 FC 4 LEU F 199 GLN F 208 -1 O ILE F 201 N LEU F 146
SHEET 4 FC 4 VAL F 177 TRP F 187 -1 O VAL F 177 N GLN F 208
SHEET 1 GA 6 ASP G 77 PRO G 81 0
SHEET 2 GA 6 ASN G 107 GLN G 111 -1 O VAL G 108 N ILE G 80
SHEET 3 GA 6 ALA G 115 TRP G 118 -1 O ALA G 115 N GLN G 111
SHEET 4 GA 6 ASN G 57 THR G 61 -1 O LEU G 58 N TRP G 118
SHEET 5 GA 6 THR G 30 GLY G 34 -1 O ARG G 32 N ALA G 59
SHEET 6 GA 6 ILE G 157 GLN G 159 1 O ILE G 157 N VAL G 31
SHEET 1 GB 4 LEU G 37 ASN G 44 0
SHEET 2 GB 4 GLU G 49 PHE G 55 -1 O GLU G 49 N ASN G 44
SHEET 3 GB 4 SER G 121 SER G 126 -1 O ALA G 122 N VAL G 54
SHEET 4 GB 4 PHE G 100 GLU G 101 -1 O GLU G 101 N ILE G 123
SHEET 1 GC 4 ILE G 90 LEU G 92 0
SHEET 2 GC 4 THR G 143 SER G 148 -1 O LYS G 147 N VAL G 91
SHEET 3 GC 4 VAL G 207 TYR G 210 -1 O VAL G 207 N PHE G 146
SHEET 4 GC 4 SER G 193 LYS G 195 -1 O ARG G 194 N THR G 208
SHEET 1 GD 2 SER G 187 ILE G 188 0
SHEET 2 GD 2 ILE G 213 GLN G 214 -1 O GLN G 214 N SER G 187
SHEET 1 HA 5 LEU H 80 LEU H 82 0
SHEET 2 HA 5 VAL H 110 VAL H 112 -1 O VAL H 110 N LEU H 82
SHEET 3 HA 5 TYR H 117 TRP H 120 -1 O THR H 119 N LEU H 111
SHEET 4 HA 5 THR H 51 TYR H 63 -1 O HIS H 60 N TRP H 120
SHEET 5 HA 5 PRO H 123 SER H 128 -1 O ALA H 124 N VAL H 56
SHEET 1 HB 6 LEU H 80 LEU H 82 0
SHEET 2 HB 6 VAL H 110 VAL H 112 -1 O VAL H 110 N LEU H 82
SHEET 3 HB 6 TYR H 117 TRP H 120 -1 O THR H 119 N LEU H 111
SHEET 4 HB 6 THR H 51 TYR H 63 -1 O HIS H 60 N TRP H 120
SHEET 5 HB 6 ASN H 32 LYS H 46 1 O ALA H 34 N ALA H 61
SHEET 6 HB 6 SER H 159 ASP H 161 1 O SER H 159 N ILE H 33
SHEET 1 HC 2 PRO H 123 SER H 128 0
SHEET 2 HC 2 THR H 51 TYR H 63 -1 O LEU H 52 N SER H 128
SHEET 1 HD 4 ILE H 92 LEU H 94 0
SHEET 2 HD 4 ASN H 143 ALA H 150 -1 O THR H 149 N VAL H 93
SHEET 3 HD 4 GLN H 213 ARG H 223 -1 O VAL H 215 N PHE H 148
SHEET 4 HD 4 ALA H 197 ILE H 201 1 O LYS H 198 N THR H 216
SHEET 1 HE 4 ILE H 92 LEU H 94 0
SHEET 2 HE 4 ASN H 143 ALA H 150 -1 O THR H 149 N VAL H 93
SHEET 3 HE 4 GLN H 213 ARG H 223 -1 O VAL H 215 N PHE H 148
SHEET 4 HE 4 TRP H 190 HIS H 194 -1 O GLU H 191 N ARG H 222
SHEET 1 HF 2 ALA H 197 ILE H 201 0
SHEET 2 HF 2 GLN H 213 ARG H 223 1 O ASP H 214 N ASN H 200
SHEET 1 IA 2 ASP I 30 THR I 32 0
SHEET 2 IA 2 SER I 157 SER I 159 1 O SER I 157 N ILE I 31
SHEET 1 IB 3 LEU I 37 ASP I 44 0
SHEET 2 IB 3 ILE I 49 ARG I 55 -1 O ILE I 49 N ASP I 44
SHEET 3 IB 3 PRO I 121 TYR I 127 -1 O ALA I 122 N VAL I 54
SHEET 1 IC 2 GLN I 58 TRP I 60 0
SHEET 2 IC 2 ILE I 116 TRP I 118 -1 O ILE I 116 N TRP I 60
SHEET 1 ID 2 ILE I 78 PRO I 81 0
SHEET 2 ID 2 LYS I 107 LEU I 110 -1 O LEU I 108 N LEU I 80
SHEET 1 IE 4 LEU I 90 LEU I 92 0
SHEET 2 IE 4 ASN I 141 ILE I 148 -1 O GLY I 147 N VAL I 91
SHEET 3 IE 4 LEU I 199 GLN I 208 -1 O ILE I 201 N LEU I 146
SHEET 4 IE 4 VAL I 177 TRP I 187 -1 O VAL I 177 N GLN I 208
SHEET 1 JA 4 LEU J 108 VAL J 109 0
SHEET 2 JA 4 SER J 114 TRP J 117 -1 O TYR J 116 N LEU J 108
SHEET 3 JA 4 ALA J 48 ASN J 60 1 O ILE J 57 N TRP J 117
SHEET 4 JA 4 PRO J 120 SER J 125 -1 O ALA J 121 N VAL J 53
SHEET 1 JB 5 LEU J 108 VAL J 109 0
SHEET 2 JB 5 SER J 114 TRP J 117 -1 O TYR J 116 N LEU J 108
SHEET 3 JB 5 ALA J 48 ASN J 60 1 O ILE J 57 N TRP J 117
SHEET 4 JB 5 VAL J 30 ASN J 43 -1 O THR J 31 N GLN J 58
SHEET 5 JB 5 LEU J 157 GLN J 158 1 O GLN J 158 N LEU J 32
SHEET 1 JC 2 PRO J 120 SER J 125 0
SHEET 2 JC 2 ALA J 48 ASN J 60 -1 O LEU J 49 N SER J 125
SHEET 1 JD 4 VAL J 89 LEU J 91 0
SHEET 2 JD 4 LEU J 143 SER J 147 -1 O ARG J 146 N VAL J 90
SHEET 3 JD 4 GLU J 207 PHE J 210 -1 O ILE J 208 N PHE J 145
SHEET 4 JD 4 LYS J 192 ASN J 193 -1 O ASN J 193 N GLU J 207
SHEET 1 JE 2 TRP J 183 HIS J 187 0
SHEET 2 JE 2 ILE J 213 ARG J 216 -1 O ILE J 213 N ARG J 186
SHEET 1 KA 6 ILE K 78 PRO K 81 0
SHEET 2 KA 6 LYS K 107 LEU K 110 -1 O LEU K 108 N LEU K 80
SHEET 3 KA 6 ILE K 116 TRP K 118 -1 O MET K 117 N LEU K 109
SHEET 4 KA 6 ILE K 49 TRP K 60 -1 O GLN K 58 N TRP K 118
SHEET 5 KA 6 PRO K 121 TYR K 127 1 O ALA K 122 N VAL K 54
SHEET 6 KA 6 PHE K 100 ALA K 101 1 O ALA K 101 N ILE K 123
SHEET 1 KB 6 ILE K 78 PRO K 81 0
SHEET 2 KB 6 LYS K 107 LEU K 110 -1 O LEU K 108 N LEU K 80
SHEET 3 KB 6 ILE K 116 TRP K 118 -1 O MET K 117 N LEU K 109
SHEET 4 KB 6 ILE K 49 TRP K 60 -1 O GLN K 58 N TRP K 118
SHEET 5 KB 6 VAL K 29 ASP K 44 -1 O THR K 32 N GLN K 59
SHEET 6 KB 6 VAL K 156 SER K 159 1 O SER K 157 N ILE K 31
SHEET 1 KC 4 LEU K 90 LEU K 92 0
SHEET 2 KC 4 GLN K 140 ILE K 148 -1 O GLY K 147 N VAL K 91
SHEET 3 KC 4 LEU K 199 GLN K 208 -1 O ILE K 201 N LEU K 146
SHEET 4 KC 4 VAL K 177 TRP K 187 -1 O VAL K 177 N GLN K 208
SHEET 1 LA 6 ASP L 77 PRO L 81 0
SHEET 2 LA 6 ASN L 107 GLN L 111 -1 O VAL L 108 N ILE L 80
SHEET 3 LA 6 ALA L 115 TRP L 118 -1 O ALA L 115 N GLN L 111
SHEET 4 LA 6 ASN L 57 THR L 61 -1 O LEU L 58 N TRP L 118
SHEET 5 LA 6 THR L 30 GLY L 34 -1 O ARG L 32 N ALA L 59
SHEET 6 LA 6 ILE L 157 GLN L 159 1 O ILE L 157 N VAL L 31
SHEET 1 LB 4 LEU L 37 ASN L 44 0
SHEET 2 LB 4 GLU L 49 PHE L 55 -1 O GLU L 49 N ASN L 44
SHEET 3 LB 4 SER L 121 SER L 126 -1 O ALA L 122 N VAL L 54
SHEET 4 LB 4 PHE L 100 GLU L 101 -1 O GLU L 101 N ILE L 123
SHEET 1 LC 4 ILE L 90 LEU L 92 0
SHEET 2 LC 4 THR L 143 SER L 148 -1 O LYS L 147 N VAL L 91
SHEET 3 LC 4 VAL L 207 TYR L 210 -1 O VAL L 207 N PHE L 146
SHEET 4 LC 4 SER L 193 LYS L 195 -1 O ARG L 194 N THR L 208
SHEET 1 LD 2 SER L 187 ILE L 188 0
SHEET 2 LD 2 ILE L 213 GLN L 214 -1 O GLN L 214 N SER L 187
SHEET 1 MA 5 LEU M 80 LEU M 82 0
SHEET 2 MA 5 VAL M 110 VAL M 112 -1 O VAL M 110 N LEU M 82
SHEET 3 MA 5 TYR M 117 TRP M 120 -1 O THR M 119 N LEU M 111
SHEET 4 MA 5 THR M 51 TYR M 63 -1 O HIS M 60 N TRP M 120
SHEET 5 MA 5 PRO M 123 SER M 128 -1 O ALA M 124 N VAL M 56
SHEET 1 MB 6 LEU M 80 LEU M 82 0
SHEET 2 MB 6 VAL M 110 VAL M 112 -1 O VAL M 110 N LEU M 82
SHEET 3 MB 6 TYR M 117 TRP M 120 -1 O THR M 119 N LEU M 111
SHEET 4 MB 6 THR M 51 TYR M 63 -1 O HIS M 60 N TRP M 120
SHEET 5 MB 6 ASN M 32 LYS M 46 1 O ALA M 34 N ALA M 61
SHEET 6 MB 6 SER M 159 ASP M 161 1 O SER M 159 N ILE M 33
SHEET 1 MC 2 PRO M 123 SER M 128 0
SHEET 2 MC 2 THR M 51 TYR M 63 -1 O LEU M 52 N SER M 128
SHEET 1 MD 4 ILE M 92 LEU M 94 0
SHEET 2 MD 4 ASN M 143 ALA M 150 -1 O THR M 149 N VAL M 93
SHEET 3 MD 4 GLN M 213 ARG M 223 -1 O VAL M 215 N PHE M 148
SHEET 4 MD 4 ALA M 197 ILE M 201 1 O LYS M 198 N THR M 216
SHEET 1 ME 4 ILE M 92 LEU M 94 0
SHEET 2 ME 4 ASN M 143 ALA M 150 -1 O THR M 149 N VAL M 93
SHEET 3 ME 4 GLN M 213 ARG M 223 -1 O VAL M 215 N PHE M 148
SHEET 4 ME 4 TRP M 190 HIS M 194 -1 O GLU M 191 N ARG M 222
SHEET 1 MF 2 ALA M 197 ILE M 201 0
SHEET 2 MF 2 GLN M 213 ARG M 223 1 O ASP M 214 N ASN M 200
SHEET 1 NA 2 ASP N 30 THR N 32 0
SHEET 2 NA 2 SER N 157 SER N 159 1 O SER N 157 N ILE N 31
SHEET 1 NB 3 LEU N 37 ASP N 44 0
SHEET 2 NB 3 ILE N 49 ARG N 55 -1 O ILE N 49 N ASP N 44
SHEET 3 NB 3 PRO N 121 TYR N 127 -1 O ALA N 122 N VAL N 54
SHEET 1 NC 2 GLN N 58 TRP N 60 0
SHEET 2 NC 2 ILE N 116 TRP N 118 -1 O ILE N 116 N TRP N 60
SHEET 1 ND 2 ILE N 78 PRO N 81 0
SHEET 2 ND 2 LYS N 107 LEU N 110 -1 O LEU N 108 N LEU N 80
SHEET 1 NE 4 LEU N 90 LEU N 92 0
SHEET 2 NE 4 ASN N 141 ILE N 148 -1 O GLY N 147 N VAL N 91
SHEET 3 NE 4 LEU N 199 GLN N 208 -1 O ILE N 201 N LEU N 146
SHEET 4 NE 4 VAL N 177 TRP N 187 -1 O VAL N 177 N GLN N 208
SHEET 1 OA 4 LEU O 108 VAL O 109 0
SHEET 2 OA 4 SER O 114 TRP O 117 -1 O TYR O 116 N LEU O 108
SHEET 3 OA 4 ALA O 48 ASN O 60 1 O ILE O 57 N TRP O 117
SHEET 4 OA 4 PRO O 120 SER O 125 -1 O ALA O 121 N VAL O 53
SHEET 1 OB 5 LEU O 108 VAL O 109 0
SHEET 2 OB 5 SER O 114 TRP O 117 -1 O TYR O 116 N LEU O 108
SHEET 3 OB 5 ALA O 48 ASN O 60 1 O ILE O 57 N TRP O 117
SHEET 4 OB 5 VAL O 30 ASN O 43 -1 O THR O 31 N GLN O 58
SHEET 5 OB 5 LEU O 157 GLN O 158 1 O GLN O 158 N LEU O 32
SHEET 1 OC 2 PRO O 120 SER O 125 0
SHEET 2 OC 2 ALA O 48 ASN O 60 -1 O LEU O 49 N SER O 125
SHEET 1 OD 4 VAL O 89 LEU O 91 0
SHEET 2 OD 4 LEU O 143 SER O 147 -1 O ARG O 146 N VAL O 90
SHEET 3 OD 4 GLU O 207 PHE O 210 -1 O ILE O 208 N PHE O 145
SHEET 4 OD 4 LYS O 192 ASN O 193 -1 O ASN O 193 N GLU O 207
SHEET 1 OE 2 TRP O 183 HIS O 187 0
SHEET 2 OE 2 ILE O 213 ARG O 216 -1 O ILE O 213 N ARG O 186
SHEET 1 PA 6 ILE P 78 PRO P 81 0
SHEET 2 PA 6 LYS P 107 LEU P 110 -1 O LEU P 108 N LEU P 80
SHEET 3 PA 6 ILE P 116 TRP P 118 -1 O MET P 117 N LEU P 109
SHEET 4 PA 6 ILE P 49 TRP P 60 -1 O GLN P 58 N TRP P 118
SHEET 5 PA 6 PRO P 121 TYR P 127 1 O ALA P 122 N VAL P 54
SHEET 6 PA 6 PHE P 100 ALA P 101 1 O ALA P 101 N ILE P 123
SHEET 1 PB 6 ILE P 78 PRO P 81 0
SHEET 2 PB 6 LYS P 107 LEU P 110 -1 O LEU P 108 N LEU P 80
SHEET 3 PB 6 ILE P 116 TRP P 118 -1 O MET P 117 N LEU P 109
SHEET 4 PB 6 ILE P 49 TRP P 60 -1 O GLN P 58 N TRP P 118
SHEET 5 PB 6 VAL P 29 ASP P 44 -1 O THR P 32 N GLN P 59
SHEET 6 PB 6 VAL P 156 SER P 159 1 O SER P 157 N ILE P 31
SHEET 1 PC 4 LEU P 90 LEU P 92 0
SHEET 2 PC 4 GLN P 140 ILE P 148 -1 O GLY P 147 N VAL P 91
SHEET 3 PC 4 LEU P 199 GLN P 208 -1 O ILE P 201 N LEU P 146
SHEET 4 PC 4 VAL P 177 TRP P 187 -1 O VAL P 177 N GLN P 208
SHEET 1 QA 6 ASP Q 77 PRO Q 81 0
SHEET 2 QA 6 ASN Q 107 GLN Q 111 -1 O VAL Q 108 N ILE Q 80
SHEET 3 QA 6 ALA Q 115 TRP Q 118 -1 O ALA Q 115 N GLN Q 111
SHEET 4 QA 6 ASN Q 57 THR Q 61 -1 O LEU Q 58 N TRP Q 118
SHEET 5 QA 6 THR Q 30 GLY Q 34 -1 O ARG Q 32 N ALA Q 59
SHEET 6 QA 6 ILE Q 157 GLN Q 159 1 O ILE Q 157 N VAL Q 31
SHEET 1 QB 4 LEU Q 37 ASN Q 44 0
SHEET 2 QB 4 GLU Q 49 PHE Q 55 -1 O GLU Q 49 N ASN Q 44
SHEET 3 QB 4 SER Q 121 SER Q 126 -1 O ALA Q 122 N VAL Q 54
SHEET 4 QB 4 PHE Q 100 GLU Q 101 -1 O GLU Q 101 N ILE Q 123
SHEET 1 QC 4 ILE Q 90 LEU Q 92 0
SHEET 2 QC 4 THR Q 143 SER Q 148 -1 O LYS Q 147 N VAL Q 91
SHEET 3 QC 4 VAL Q 207 TYR Q 210 -1 O VAL Q 207 N PHE Q 146
SHEET 4 QC 4 SER Q 193 LYS Q 195 -1 O ARG Q 194 N THR Q 208
SHEET 1 QD 2 SER Q 187 ILE Q 188 0
SHEET 2 QD 2 ILE Q 213 GLN Q 214 -1 O GLN Q 214 N SER Q 187
SHEET 1 RA 5 LEU R 80 LEU R 82 0
SHEET 2 RA 5 VAL R 110 VAL R 112 -1 O VAL R 110 N LEU R 82
SHEET 3 RA 5 TYR R 117 TRP R 120 -1 O THR R 119 N LEU R 111
SHEET 4 RA 5 THR R 51 TYR R 63 -1 O HIS R 60 N TRP R 120
SHEET 5 RA 5 PRO R 123 SER R 128 -1 O ALA R 124 N VAL R 56
SHEET 1 RB 6 LEU R 80 LEU R 82 0
SHEET 2 RB 6 VAL R 110 VAL R 112 -1 O VAL R 110 N LEU R 82
SHEET 3 RB 6 TYR R 117 TRP R 120 -1 O THR R 119 N LEU R 111
SHEET 4 RB 6 THR R 51 TYR R 63 -1 O HIS R 60 N TRP R 120
SHEET 5 RB 6 ASN R 32 LYS R 46 1 O ALA R 34 N ALA R 61
SHEET 6 RB 6 SER R 159 ASP R 161 1 O SER R 159 N ILE R 33
SHEET 1 RC 2 PRO R 123 SER R 128 0
SHEET 2 RC 2 THR R 51 TYR R 63 -1 O LEU R 52 N SER R 128
SHEET 1 RD 4 ILE R 92 LEU R 94 0
SHEET 2 RD 4 ASN R 143 ALA R 150 -1 O THR R 149 N VAL R 93
SHEET 3 RD 4 GLN R 213 ARG R 223 -1 O VAL R 215 N PHE R 148
SHEET 4 RD 4 ALA R 197 ILE R 201 1 O LYS R 198 N THR R 216
SHEET 1 RE 4 ILE R 92 LEU R 94 0
SHEET 2 RE 4 ASN R 143 ALA R 150 -1 O THR R 149 N VAL R 93
SHEET 3 RE 4 GLN R 213 ARG R 223 -1 O VAL R 215 N PHE R 148
SHEET 4 RE 4 TRP R 190 HIS R 194 -1 O GLU R 191 N ARG R 222
SHEET 1 RF 2 ALA R 197 ILE R 201 0
SHEET 2 RF 2 GLN R 213 ARG R 223 1 O ASP R 214 N ASN R 200
SHEET 1 SA 2 ASP S 30 THR S 32 0
SHEET 2 SA 2 SER S 157 SER S 159 1 O SER S 157 N ILE S 31
SHEET 1 SB 3 LEU S 37 ASP S 44 0
SHEET 2 SB 3 ILE S 49 ARG S 55 -1 O ILE S 49 N ASP S 44
SHEET 3 SB 3 PRO S 121 TYR S 127 -1 O ALA S 122 N VAL S 54
SHEET 1 SC 2 GLN S 58 TRP S 60 0
SHEET 2 SC 2 ILE S 116 TRP S 118 -1 O ILE S 116 N TRP S 60
SHEET 1 SD 2 ILE S 78 PRO S 81 0
SHEET 2 SD 2 LYS S 107 LEU S 110 -1 O LEU S 108 N LEU S 80
SHEET 1 SE 4 LEU S 90 LEU S 92 0
SHEET 2 SE 4 ASN S 141 ILE S 148 -1 O GLY S 147 N VAL S 91
SHEET 3 SE 4 LEU S 199 GLN S 208 -1 O ILE S 201 N LEU S 146
SHEET 4 SE 4 VAL S 177 TRP S 187 -1 O VAL S 177 N GLN S 208
SHEET 1 TA 4 LEU T 108 VAL T 109 0
SHEET 2 TA 4 SER T 114 TRP T 117 -1 O TYR T 116 N LEU T 108
SHEET 3 TA 4 ALA T 48 ASN T 60 1 O ILE T 57 N TRP T 117
SHEET 4 TA 4 PRO T 120 SER T 125 -1 O ALA T 121 N VAL T 53
SHEET 1 TB 5 LEU T 108 VAL T 109 0
SHEET 2 TB 5 SER T 114 TRP T 117 -1 O TYR T 116 N LEU T 108
SHEET 3 TB 5 ALA T 48 ASN T 60 1 O ILE T 57 N TRP T 117
SHEET 4 TB 5 VAL T 30 ASN T 43 -1 O THR T 31 N GLN T 58
SHEET 5 TB 5 LEU T 157 GLN T 158 1 O GLN T 158 N LEU T 32
SHEET 1 TC 2 PRO T 120 SER T 125 0
SHEET 2 TC 2 ALA T 48 ASN T 60 -1 O LEU T 49 N SER T 125
SHEET 1 TD 4 VAL T 89 LEU T 91 0
SHEET 2 TD 4 LEU T 143 SER T 147 -1 O ARG T 146 N VAL T 90
SHEET 3 TD 4 GLU T 207 PHE T 210 -1 O ILE T 208 N PHE T 145
SHEET 4 TD 4 LYS T 192 ASN T 193 -1 O ASN T 193 N GLU T 207
SHEET 1 TE 2 TRP T 183 HIS T 187 0
SHEET 2 TE 2 ILE T 213 ARG T 216 -1 O ILE T 213 N ARG T 186
SHEET 1 UA 6 ILE U 78 PRO U 81 0
SHEET 2 UA 6 LYS U 107 LEU U 110 -1 O LEU U 108 N LEU U 80
SHEET 3 UA 6 ILE U 116 TRP U 118 -1 O MET U 117 N LEU U 109
SHEET 4 UA 6 ILE U 49 TRP U 60 -1 O GLN U 58 N TRP U 118
SHEET 5 UA 6 PRO U 121 TYR U 127 1 O ALA U 122 N VAL U 54
SHEET 6 UA 6 PHE U 100 ALA U 101 1 O ALA U 101 N ILE U 123
SHEET 1 UB 6 ILE U 78 PRO U 81 0
SHEET 2 UB 6 LYS U 107 LEU U 110 -1 O LEU U 108 N LEU U 80
SHEET 3 UB 6 ILE U 116 TRP U 118 -1 O MET U 117 N LEU U 109
SHEET 4 UB 6 ILE U 49 TRP U 60 -1 O GLN U 58 N TRP U 118
SHEET 5 UB 6 VAL U 29 ASP U 44 -1 O THR U 32 N GLN U 59
SHEET 6 UB 6 VAL U 156 SER U 159 1 O SER U 157 N ILE U 31
SHEET 1 UC 4 LEU U 90 LEU U 92 0
SHEET 2 UC 4 GLN U 140 ILE U 148 -1 O GLY U 147 N VAL U 91
SHEET 3 UC 4 LEU U 199 GLN U 208 -1 O ILE U 201 N LEU U 146
SHEET 4 UC 4 VAL U 177 TRP U 187 -1 O VAL U 177 N GLN U 208
SHEET 1 VA 6 ASP V 77 PRO V 81 0
SHEET 2 VA 6 ASN V 107 GLN V 111 -1 O VAL V 108 N ILE V 80
SHEET 3 VA 6 ALA V 115 TRP V 118 -1 O ALA V 115 N GLN V 111
SHEET 4 VA 6 ASN V 57 THR V 61 -1 O LEU V 58 N TRP V 118
SHEET 5 VA 6 THR V 30 GLY V 34 -1 O ARG V 32 N ALA V 59
SHEET 6 VA 6 ILE V 157 GLN V 159 1 O ILE V 157 N VAL V 31
SHEET 1 VB 4 LEU V 37 ASN V 44 0
SHEET 2 VB 4 GLU V 49 PHE V 55 -1 O GLU V 49 N ASN V 44
SHEET 3 VB 4 SER V 121 SER V 126 -1 O ALA V 122 N VAL V 54
SHEET 4 VB 4 PHE V 100 GLU V 101 -1 O GLU V 101 N ILE V 123
SHEET 1 VC 4 ILE V 90 LEU V 92 0
SHEET 2 VC 4 THR V 143 SER V 148 -1 O LYS V 147 N VAL V 91
SHEET 3 VC 4 VAL V 207 TYR V 210 -1 O VAL V 207 N PHE V 146
SHEET 4 VC 4 SER V 193 LYS V 195 -1 O ARG V 194 N THR V 208
SHEET 1 VD 2 SER V 187 ILE V 188 0
SHEET 2 VD 2 ILE V 213 GLN V 214 -1 O GLN V 214 N SER V 187
SHEET 1 WA 5 LEU W 80 LEU W 82 0
SHEET 2 WA 5 VAL W 110 VAL W 112 -1 O VAL W 110 N LEU W 82
SHEET 3 WA 5 TYR W 117 TRP W 120 -1 O THR W 119 N LEU W 111
SHEET 4 WA 5 THR W 51 TYR W 63 -1 O HIS W 60 N TRP W 120
SHEET 5 WA 5 PRO W 123 SER W 128 -1 O ALA W 124 N VAL W 56
SHEET 1 WB 6 LEU W 80 LEU W 82 0
SHEET 2 WB 6 VAL W 110 VAL W 112 -1 O VAL W 110 N LEU W 82
SHEET 3 WB 6 TYR W 117 TRP W 120 -1 O THR W 119 N LEU W 111
SHEET 4 WB 6 THR W 51 TYR W 63 -1 O HIS W 60 N TRP W 120
SHEET 5 WB 6 ASN W 32 LYS W 46 1 O ALA W 34 N ALA W 61
SHEET 6 WB 6 SER W 159 ASP W 161 1 O SER W 159 N ILE W 33
SHEET 1 WC 2 PRO W 123 SER W 128 0
SHEET 2 WC 2 THR W 51 TYR W 63 -1 O LEU W 52 N SER W 128
SHEET 1 WD 4 ILE W 92 LEU W 94 0
SHEET 2 WD 4 ASN W 143 ALA W 150 -1 O THR W 149 N VAL W 93
SHEET 3 WD 4 GLN W 213 ARG W 223 -1 O VAL W 215 N PHE W 148
SHEET 4 WD 4 ALA W 197 ILE W 201 1 O LYS W 198 N THR W 216
SHEET 1 WE 4 ILE W 92 LEU W 94 0
SHEET 2 WE 4 ASN W 143 ALA W 150 -1 O THR W 149 N VAL W 93
SHEET 3 WE 4 GLN W 213 ARG W 223 -1 O VAL W 215 N PHE W 148
SHEET 4 WE 4 TRP W 190 HIS W 194 -1 O GLU W 191 N ARG W 222
SHEET 1 WF 2 ALA W 197 ILE W 201 0
SHEET 2 WF 2 GLN W 213 ARG W 223 1 O ASP W 214 N ASN W 200
SHEET 1 XA 2 ASP X 30 THR X 32 0
SHEET 2 XA 2 SER X 157 SER X 159 1 O SER X 157 N ILE X 31
SHEET 1 XB 3 LEU X 37 ASP X 44 0
SHEET 2 XB 3 ILE X 49 ARG X 55 -1 O ILE X 49 N ASP X 44
SHEET 3 XB 3 PRO X 121 TYR X 127 -1 O ALA X 122 N VAL X 54
SHEET 1 XC 2 GLN X 58 TRP X 60 0
SHEET 2 XC 2 ILE X 116 TRP X 118 -1 O ILE X 116 N TRP X 60
SHEET 1 XD 2 ILE X 78 PRO X 81 0
SHEET 2 XD 2 LYS X 107 LEU X 110 -1 O LEU X 108 N LEU X 80
SHEET 1 XE 4 LEU X 90 LEU X 92 0
SHEET 2 XE 4 ASN X 141 ILE X 148 -1 O GLY X 147 N VAL X 91
SHEET 3 XE 4 LEU X 199 GLN X 208 -1 O ILE X 201 N LEU X 146
SHEET 4 XE 4 VAL X 177 TRP X 187 -1 O VAL X 177 N GLN X 208
SHEET 1 YA 4 LEU Y 108 VAL Y 109 0
SHEET 2 YA 4 SER Y 114 TRP Y 117 -1 O TYR Y 116 N LEU Y 108
SHEET 3 YA 4 ALA Y 48 ASN Y 60 1 O ILE Y 57 N TRP Y 117
SHEET 4 YA 4 PRO Y 120 SER Y 125 -1 O ALA Y 121 N VAL Y 53
SHEET 1 YB 5 LEU Y 108 VAL Y 109 0
SHEET 2 YB 5 SER Y 114 TRP Y 117 -1 O TYR Y 116 N LEU Y 108
SHEET 3 YB 5 ALA Y 48 ASN Y 60 1 O ILE Y 57 N TRP Y 117
SHEET 4 YB 5 VAL Y 30 ASN Y 43 -1 O THR Y 31 N GLN Y 58
SHEET 5 YB 5 LEU Y 157 GLN Y 158 1 O GLN Y 158 N LEU Y 32
SHEET 1 YC 2 PRO Y 120 SER Y 125 0
SHEET 2 YC 2 ALA Y 48 ASN Y 60 -1 O LEU Y 49 N SER Y 125
SHEET 1 YD 4 VAL Y 89 LEU Y 91 0
SHEET 2 YD 4 LEU Y 143 SER Y 147 -1 O ARG Y 146 N VAL Y 90
SHEET 3 YD 4 GLU Y 207 PHE Y 210 -1 O ILE Y 208 N PHE Y 145
SHEET 4 YD 4 LYS Y 192 ASN Y 193 -1 O ASN Y 193 N GLU Y 207
SHEET 1 YE 2 TRP Y 183 HIS Y 187 0
SHEET 2 YE 2 ILE Y 213 ARG Y 216 -1 O ILE Y 213 N ARG Y 186
SHEET 1 ZA 6 ILE Z 78 PRO Z 81 0
SHEET 2 ZA 6 LYS Z 107 LEU Z 110 -1 O LEU Z 108 N LEU Z 80
SHEET 3 ZA 6 ILE Z 116 TRP Z 118 -1 O MET Z 117 N LEU Z 109
SHEET 4 ZA 6 ILE Z 49 TRP Z 60 -1 O GLN Z 58 N TRP Z 118
SHEET 5 ZA 6 PRO Z 121 TYR Z 127 1 O ALA Z 122 N VAL Z 54
SHEET 6 ZA 6 PHE Z 100 ALA Z 101 1 O ALA Z 101 N ILE Z 123
SHEET 1 ZB 6 ILE Z 78 PRO Z 81 0
SHEET 2 ZB 6 LYS Z 107 LEU Z 110 -1 O LEU Z 108 N LEU Z 80
SHEET 3 ZB 6 ILE Z 116 TRP Z 118 -1 O MET Z 117 N LEU Z 109
SHEET 4 ZB 6 ILE Z 49 TRP Z 60 -1 O GLN Z 58 N TRP Z 118
SHEET 5 ZB 6 VAL Z 29 ASP Z 44 -1 O THR Z 32 N GLN Z 59
SHEET 6 ZB 6 VAL Z 156 SER Z 159 1 O SER Z 157 N ILE Z 31
SHEET 1 ZC 4 LEU Z 90 LEU Z 92 0
SHEET 2 ZC 4 GLN Z 140 ILE Z 148 -1 O GLY Z 147 N VAL Z 91
SHEET 3 ZC 4 LEU Z 199 GLN Z 208 -1 O ILE Z 201 N LEU Z 146
SHEET 4 ZC 4 VAL Z 177 TRP Z 187 -1 O VAL Z 177 N GLN Z 208
SSBOND 1 CYS 0 128 CYS 0 142 1555 1555 2.05
SSBOND 2 CYS 0 128 CYS A 128 1555 1655 2.87
SSBOND 3 CYS 1 130 CYS 1 144 1555 1555 1.97
SSBOND 4 CYS 2 128 CYS 2 142 1555 1555 2.05
SSBOND 5 CYS 2 192 CYS 2 193 1555 1555 2.06
SSBOND 6 CYS 3 127 CYS 3 141 1555 1555 2.06
SSBOND 7 CYS A 128 CYS A 142 1555 1555 2.05
SSBOND 8 CYS A 142 CYS M 130 1555 1565 2.21
SSBOND 9 CYS A 192 CYS A 193 1555 1555 2.05
SSBOND 10 CYS B 128 CYS B 142 1555 1555 2.05
SSBOND 11 CYS C 130 CYS C 144 1555 1555 1.97
SSBOND 12 CYS D 128 CYS D 142 1555 1555 2.05
SSBOND 13 CYS D 192 CYS D 193 1555 1555 2.06
SSBOND 14 CYS E 127 CYS E 141 1555 1555 2.06
SSBOND 15 CYS F 128 CYS F 142 1555 1555 2.05
SSBOND 16 CYS F 192 CYS F 193 1555 1555 2.05
SSBOND 17 CYS G 128 CYS G 142 1555 1555 2.05
SSBOND 18 CYS H 130 CYS H 144 1555 1555 1.97
SSBOND 19 CYS I 128 CYS I 142 1555 1555 2.05
SSBOND 20 CYS I 192 CYS I 193 1555 1555 2.06
SSBOND 21 CYS J 127 CYS J 141 1555 1555 2.06
SSBOND 22 CYS K 128 CYS K 142 1555 1555 2.05
SSBOND 23 CYS K 192 CYS K 193 1555 1555 2.05
SSBOND 24 CYS L 128 CYS L 142 1555 1555 2.05
SSBOND 25 CYS M 130 CYS M 144 1555 1555 1.97
SSBOND 26 CYS N 128 CYS N 142 1555 1555 2.05
SSBOND 27 CYS N 192 CYS N 193 1555 1555 2.06
SSBOND 28 CYS O 127 CYS O 141 1555 1555 2.07
SSBOND 29 CYS P 128 CYS P 142 1555 1555 2.05
SSBOND 30 CYS P 192 CYS P 193 1555 1555 2.05
SSBOND 31 CYS Q 128 CYS Q 142 1555 1555 2.05
SSBOND 32 CYS R 130 CYS R 144 1555 1555 1.97
SSBOND 33 CYS S 128 CYS S 142 1555 1555 2.05
SSBOND 34 CYS S 192 CYS S 193 1555 1555 2.06
SSBOND 35 CYS T 127 CYS T 141 1555 1555 2.06
SSBOND 36 CYS U 128 CYS U 142 1555 1555 2.05
SSBOND 37 CYS U 192 CYS U 193 1555 1555 2.05
SSBOND 38 CYS V 128 CYS V 142 1555 1555 2.05
SSBOND 39 CYS W 130 CYS W 144 1555 1555 1.97
SSBOND 40 CYS X 128 CYS X 142 1555 1555 2.05
SSBOND 41 CYS X 192 CYS X 193 1555 1555 2.06
SSBOND 42 CYS Y 127 CYS Y 141 1555 1555 2.06
SSBOND 43 CYS Z 128 CYS Z 142 1555 1555 2.05
SSBOND 44 CYS Z 192 CYS Z 193 1555 1555 2.05
CRYST1 1.000 1.000 1.000 90.00 90.00 90.00 P 1 1
ORIGX1 1.000000 0.000000 0.000000 0.00000
ORIGX2 0.000000 1.000000 0.000000 0.00000
ORIGX3 0.000000 0.000000 1.000000 0.00000
SCALE1 1.000000 0.000000 0.000000 0.00000
SCALE2 0.000000 1.000000 0.000000 0.00000
SCALE3 0.000000 0.000000 1.000000 0.00000
(ATOM LINES ARE NOT SHOWN.)
END
