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Database: PDB
Entry: 4C7U
LinkDB: 4C7U
Original site: 4C7U 
HEADER    OXIDOREDUCTASE                          25-SEP-13   4C7U              
TITLE     CRYSTAL STRUCTURE OF MANGANESE SUPEROXIDE DISMUTASE FROM ARABIDOPSIS  
TITLE    2 THALIANA                                                             
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: SUPEROXIDE DISMUTASE [MN] 1, MITOCHONDRIAL;                
COMPND   3 CHAIN: A, B, C, D, E, F, G, H;                                       
COMPND   4 SYNONYM: MANGANESE SUPEROXIDE DISMUTASE, PROTEIN MANGANESE SUPEROXIDE
COMPND   5 ATMSD1, PROTEIN MATERNAL EFFECT EMBRYO ARREST 33;                    
COMPND   6 EC: 1.15.1.1;                                                        
COMPND   7 ENGINEERED: YES                                                      
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 ORGANISM_SCIENTIFIC: ARABIDOPSIS THALIANA;                           
SOURCE   3 ORGANISM_COMMON: MOUSE-EAR CRESS;                                    
SOURCE   4 ORGANISM_TAXID: 3702;                                                
SOURCE   5 EXPRESSION_SYSTEM: ESCHERICHIA COLI;                                 
SOURCE   6 EXPRESSION_SYSTEM_TAXID: 469008;                                     
SOURCE   7 EXPRESSION_SYSTEM_STRAIN: BL21(DE3);                                 
SOURCE   8 EXPRESSION_SYSTEM_VARIANT: ROSETTA PLYSS;                            
SOURCE   9 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                              
SOURCE  10 EXPRESSION_SYSTEM_VECTOR: PDEST17                                    
KEYWDS    OXIDOREDUCTASE, OXIDATIVE STRESS, OXIDATION-REDUCTION                 
EXPDTA    X-RAY DIFFRACTION                                                     
AUTHOR    A.MARQUES,S.P.SANTOS,M.ROSA,M.A.CARRONDO,I.A.ABREU,C.V.ROMAO,C.FRAZAO 
REVDAT   4   06-FEB-19 4C7U    1       REMARK                                   
REVDAT   3   30-JAN-19 4C7U    1       REMARK                                   
REVDAT   2   06-SEP-17 4C7U    1       REMARK                                   
REVDAT   1   15-OCT-14 4C7U    0                                                
JRNL        AUTH   A.MARQUES,S.P.SANTOS,M.ROSA,M.A.CARRONDO,I.A.ABREU,          
JRNL        AUTH 2 C.V.ROMAO,C.FRAZAO                                           
JRNL        TITL   CRYSTAL STRUCTURE OF THE ARABIDOPSIS THALIANA MANGANESE      
JRNL        TITL 2 SUPEROXIDE DISMUTASE AT 1.95 A RESOLUTION                    
JRNL        REF    TO BE PUBLISHED                                              
JRNL        REFN                                                                
REMARK   2                                                                      
REMARK   2 RESOLUTION.    1.95 ANGSTROMS.                                       
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   PROGRAM     : PHENIX (PHENIX.REFINE)                               
REMARK   3   AUTHORS     : PAUL ADAMS,PAVEL AFONINE,VINCENT CHEN,IAN            
REMARK   3               : DAVIS,KRESHNA GOPAL,RALF GROSSE-KUNSTLEVE,           
REMARK   3               : LI-WEI HUNG,ROBERT IMMORMINO,TOM IOERGER,            
REMARK   3               : AIRLIE MCCOY,ERIK MCKEE,NIGEL MORIARTY,              
REMARK   3               : REETAL PAI,RANDY READ,JANE RICHARDSON,               
REMARK   3               : DAVID RICHARDSON,TOD ROMO,JIM SACCHETTINI,           
REMARK   3               : NICHOLAS SAUTER,JACOB SMITH,LAURENT                  
REMARK   3               : STORONI,TOM TERWILLIGER,PETER ZWART                  
REMARK   3                                                                      
REMARK   3    REFINEMENT TARGET : ML                                            
REMARK   3                                                                      
REMARK   3  DATA USED IN REFINEMENT.                                            
REMARK   3   RESOLUTION RANGE HIGH (ANGSTROMS) : 1.95                           
REMARK   3   RESOLUTION RANGE LOW  (ANGSTROMS) : 53.99                          
REMARK   3   MIN(FOBS/SIGMA_FOBS)              : 1.960                          
REMARK   3   COMPLETENESS FOR RANGE        (%) : 92.9                           
REMARK   3   NUMBER OF REFLECTIONS             : 98653                          
REMARK   3                                                                      
REMARK   3  FIT TO DATA USED IN REFINEMENT.                                     
REMARK   3   R VALUE     (WORKING + TEST SET) : 0.173                           
REMARK   3   R VALUE            (WORKING SET) : 0.173                           
REMARK   3   FREE R VALUE                     : NULL                            
REMARK   3   FREE R VALUE TEST SET SIZE   (%) : NULL                            
REMARK   3   FREE R VALUE TEST SET COUNT      : NULL                            
REMARK   3                                                                      
REMARK   3  FIT TO DATA USED IN REFINEMENT (IN BINS).                           
REMARK   3   BIN  RESOLUTION RANGE  COMPL.    NWORK NFREE   RWORK  RFREE        
REMARK   3     1 54.0061 -  6.0599    0.92     3252  3252  0.1849 0.1849        
REMARK   3     2  6.0599 -  4.8109    0.95     3381  3381  0.1643 0.1643        
REMARK   3     3  4.8109 -  4.2030    0.96     3343  3343  0.1508 0.1508        
REMARK   3     4  4.2030 -  3.8188    0.97     3452  3452  0.1448 0.1448        
REMARK   3     5  3.8188 -  3.5452    0.97     3430  3430  0.1676 0.1676        
REMARK   3     6  3.5452 -  3.3362    0.94     3281  3281  0.1461 0.1461        
REMARK   3     7  3.3362 -  3.1691    0.95     3377  3377  0.1502 0.1502        
REMARK   3     8  3.1691 -  3.0312    0.95     3376  3376  0.1431 0.1431        
REMARK   3     9  3.0312 -  2.9145    0.95     3359  3359  0.1483 0.1483        
REMARK   3    10  2.9145 -  2.8139    0.95     3333  3333  0.1474 0.1474        
REMARK   3    11  2.8139 -  2.7260    0.95     3402  3402  0.1467 0.1467        
REMARK   3    12  2.7260 -  2.6480    0.90     3199  3199  0.1458 0.1458        
REMARK   3    13  2.6480 -  2.5783    0.92     3209  3209  0.1560 0.1560        
REMARK   3    14  2.5783 -  2.5154    0.92     3263  3263  0.1646 0.1646        
REMARK   3    15  2.5154 -  2.4582    0.91     3169  3169  0.1790 0.1790        
REMARK   3    16  2.4582 -  2.4059    0.92     3328  3328  0.1938 0.1938        
REMARK   3    17  2.4059 -  2.3578    0.92     3206  3206  0.1873 0.1873        
REMARK   3    18  2.3578 -  2.3133    0.92     3301  3301  0.1791 0.1791        
REMARK   3    19  2.3133 -  2.2720    0.94     3282  3282  0.1929 0.1929        
REMARK   3    20  2.2720 -  2.2335    0.93     3349  3349  0.1954 0.1954        
REMARK   3    21  2.2335 -  2.1975    0.88     3055  3055  0.1958 0.1958        
REMARK   3    22  2.1975 -  2.1636    0.90     3261  3261  0.2110 0.2110        
REMARK   3    23  2.1636 -  2.1318    0.92     3211  3211  0.2342 0.2342        
REMARK   3    24  2.1318 -  2.1018    0.92     3253  3253  0.2408 0.2408        
REMARK   3    25  2.1018 -  2.0734    0.91     3253  3253  0.2394 0.2394        
REMARK   3    26  2.0734 -  2.0465    0.94     3267  3267  0.2461 0.2461        
REMARK   3    27  2.0465 -  2.0209    0.92     3316  3316  0.2725 0.2725        
REMARK   3    28  2.0209 -  1.9965    0.93     3289  3289  0.2692 0.2692        
REMARK   3    29  1.9965 -  1.9733    0.94     3294  3294  0.2866 0.2866        
REMARK   3    30  1.9733 -  1.9511    0.88     3162  3162  0.2956 0.2956        
REMARK   3                                                                      
REMARK   3  BULK SOLVENT MODELLING.                                             
REMARK   3   METHOD USED        : FLAT BULK SOLVENT MODEL                       
REMARK   3   SOLVENT RADIUS     : 1.11                                          
REMARK   3   SHRINKAGE RADIUS   : 0.90                                          
REMARK   3   K_SOL              : NULL                                          
REMARK   3   B_SOL              : NULL                                          
REMARK   3                                                                      
REMARK   3  ERROR ESTIMATES.                                                    
REMARK   3   COORDINATE ERROR (MAXIMUM-LIKELIHOOD BASED)     : 0.190            
REMARK   3   PHASE ERROR (DEGREES, MAXIMUM-LIKELIHOOD BASED) : 16.140           
REMARK   3                                                                      
REMARK   3  B VALUES.                                                           
REMARK   3   FROM WILSON PLOT           (A**2) : 28.14                          
REMARK   3   MEAN B VALUE      (OVERALL, A**2) : NULL                           
REMARK   3   OVERALL ANISOTROPIC B VALUE.                                       
REMARK   3    B11 (A**2) : NULL                                                 
REMARK   3    B22 (A**2) : NULL                                                 
REMARK   3    B33 (A**2) : NULL                                                 
REMARK   3    B12 (A**2) : NULL                                                 
REMARK   3    B13 (A**2) : NULL                                                 
REMARK   3    B23 (A**2) : NULL                                                 
REMARK   3                                                                      
REMARK   3  TWINNING INFORMATION.                                               
REMARK   3   FRACTION: NULL                                                     
REMARK   3   OPERATOR: NULL                                                     
REMARK   3                                                                      
REMARK   3  DEVIATIONS FROM IDEAL VALUES.                                       
REMARK   3                 RMSD          COUNT                                  
REMARK   3   BOND      :  0.012          13032                                  
REMARK   3   ANGLE     :  1.150          17658                                  
REMARK   3   CHIRALITY :  0.054           1882                                  
REMARK   3   PLANARITY :  0.007           2270                                  
REMARK   3   DIHEDRAL  : 11.786           4636                                  
REMARK   3                                                                      
REMARK   3  TLS DETAILS                                                         
REMARK   3   NUMBER OF TLS GROUPS  : 51                                         
REMARK   3   TLS GROUP : 1                                                      
REMARK   3    SELECTION: (CHAIN A AND RESID -1:35)                              
REMARK   3    ORIGIN FOR THE GROUP (A):  79.4880  37.2077 109.2782              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1925 T22:   0.1355                                     
REMARK   3      T33:   0.0581 T12:   0.0676                                     
REMARK   3      T13:   0.0317 T23:  -0.0168                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0133 L22:   0.0233                                     
REMARK   3      L33:   0.0183 L12:   0.0105                                     
REMARK   3      L13:   0.0035 L23:  -0.0053                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0154 S12:   0.0608 S13:  -0.0204                       
REMARK   3      S21:  -0.0892 S22:   0.0153 S23:  -0.0529                       
REMARK   3      S31:   0.0052 S32:  -0.0121 S33:   0.0168                       
REMARK   3   TLS GROUP : 2                                                      
REMARK   3    SELECTION: (CHAIN A AND RESID 36:67)                              
REMARK   3    ORIGIN FOR THE GROUP (A):  92.5461  41.9100 129.3698              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1021 T22:   0.1085                                     
REMARK   3      T33:   0.1017 T12:   0.0049                                     
REMARK   3      T13:   0.0399 T23:  -0.0262                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0060 L22:   0.0074                                     
REMARK   3      L33:   0.0096 L12:   0.0042                                     
REMARK   3      L13:   0.0057 L23:   0.0014                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0202 S12:  -0.0063 S13:   0.0185                       
REMARK   3      S21:  -0.0383 S22:   0.0455 S23:  -0.0200                       
REMARK   3      S31:   0.0113 S32:   0.0314 S33:   0.0182                       
REMARK   3   TLS GROUP : 3                                                      
REMARK   3    SELECTION: (CHAIN A AND RESID 68:93)                              
REMARK   3    ORIGIN FOR THE GROUP (A):  70.2850  32.1167 114.0899              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1783 T22:   0.0801                                     
REMARK   3      T33:   0.1346 T12:   0.0047                                     
REMARK   3      T13:   0.0038 T23:   0.0031                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0386 L22:   0.0004                                     
REMARK   3      L33:   0.0100 L12:   0.0054                                     
REMARK   3      L13:  -0.0086 L23:   0.0009                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0144 S12:  -0.0142 S13:  -0.0144                       
REMARK   3      S21:  -0.0974 S22:  -0.0174 S23:   0.0221                       
REMARK   3      S31:   0.0673 S32:   0.0076 S33:  -0.0022                       
REMARK   3   TLS GROUP : 4                                                      
REMARK   3    SELECTION: (CHAIN A AND RESID 94:119)                             
REMARK   3    ORIGIN FOR THE GROUP (A):  56.6515  35.4394 122.4663              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.0839 T22:   0.1049                                     
REMARK   3      T33:   0.1027 T12:  -0.0081                                     
REMARK   3      T13:  -0.0074 T23:   0.0262                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0028 L22:   0.0007                                     
REMARK   3      L33:   0.0044 L12:  -0.0014                                     
REMARK   3      L13:  -0.0009 L23:   0.0017                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0442 S12:  -0.0557 S13:   0.0063                       
REMARK   3      S21:  -0.0019 S22:   0.0157 S23:   0.0013                       
REMARK   3      S31:   0.0244 S32:  -0.0338 S33:   0.0001                       
REMARK   3   TLS GROUP : 5                                                      
REMARK   3    SELECTION: (CHAIN A AND RESID 120:137)                            
REMARK   3    ORIGIN FOR THE GROUP (A):  67.0458  38.0551 127.7822              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.0604 T22:   0.0480                                     
REMARK   3      T33:   0.0976 T12:  -0.0106                                     
REMARK   3      T13:  -0.0031 T23:   0.0551                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0014 L22:   0.0159                                     
REMARK   3      L33:   0.0542 L12:  -0.0065                                     
REMARK   3      L13:  -0.0094 L23:   0.0291                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0772 S12:  -0.0427 S13:  -0.0333                       
REMARK   3      S21:  -0.0010 S22:   0.0310 S23:  -0.0231                       
REMARK   3      S31:  -0.0008 S32:  -0.0419 S33:   0.0457                       
REMARK   3   TLS GROUP : 6                                                      
REMARK   3    SELECTION: (CHAIN A AND RESID 138:190)                            
REMARK   3    ORIGIN FOR THE GROUP (A):  68.1491  42.0581 117.6643              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1035 T22:   0.0609                                     
REMARK   3      T33:   0.0594 T12:   0.0106                                     
REMARK   3      T13:   0.0047 T23:  -0.0022                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0123 L22:   0.0176                                     
REMARK   3      L33:   0.0345 L12:   0.0058                                     
REMARK   3      L13:  -0.0085 L23:   0.0213                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0659 S12:   0.0031 S13:  -0.0041                       
REMARK   3      S21:  -0.0555 S22:  -0.0162 S23:  -0.0209                       
REMARK   3      S31:  -0.0455 S32:  -0.0254 S33:   0.0329                       
REMARK   3   TLS GROUP : 7                                                      
REMARK   3    SELECTION: (CHAIN A AND RESID 191:202)                            
REMARK   3    ORIGIN FOR THE GROUP (A):  68.4143  24.4175 122.6922              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.2508 T22:   0.1722                                     
REMARK   3      T33:   0.2530 T12:  -0.0102                                     
REMARK   3      T13:  -0.0503 T23:   0.0434                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0065 L22:   0.0010                                     
REMARK   3      L33:   0.0032 L12:   0.0009                                     
REMARK   3      L13:  -0.0040 L23:  -0.0003                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0112 S12:   0.0091 S13:   0.0027                       
REMARK   3      S21:   0.0055 S22:   0.0266 S23:  -0.0207                       
REMARK   3      S31:   0.0009 S32:   0.0195 S33:   0.0001                       
REMARK   3   TLS GROUP : 8                                                      
REMARK   3    SELECTION: (CHAIN B AND RESID -2:35)                              
REMARK   3    ORIGIN FOR THE GROUP (A):  50.5159  38.1994 103.4386              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.0815 T22:  -0.0346                                     
REMARK   3      T33:  -0.0716 T12:   0.0081                                     
REMARK   3      T13:  -0.0070 T23:  -0.1525                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0079 L22:   0.0007                                     
REMARK   3      L33:   0.0400 L12:  -0.0026                                     
REMARK   3      L13:   0.0169 L23:  -0.0062                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0459 S12:  -0.0227 S13:   0.0356                       
REMARK   3      S21:   0.0801 S22:   0.0123 S23:  -0.0666                       
REMARK   3      S31:   0.0184 S32:   0.0533 S33:   0.0748                       
REMARK   3   TLS GROUP : 9                                                      
REMARK   3    SELECTION: (CHAIN B AND RESID 36:62)                              
REMARK   3    ORIGIN FOR THE GROUP (A):  64.8145  34.8283  83.0238              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.0507 T22:   0.1137                                     
REMARK   3      T33:   0.0788 T12:  -0.0113                                     
REMARK   3      T13:  -0.0040 T23:  -0.0507                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0043 L22:   0.0064                                     
REMARK   3      L33:   0.0092 L12:   0.0054                                     
REMARK   3      L13:  -0.0043 L23:  -0.0028                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0068 S12:   0.0382 S13:   0.0028                       
REMARK   3      S21:   0.0280 S22:   0.0447 S23:  -0.0028                       
REMARK   3      S31:  -0.0051 S32:   0.0330 S33:   0.0032                       
REMARK   3   TLS GROUP : 10                                                     
REMARK   3    SELECTION: (CHAIN B AND RESID 63:93)                              
REMARK   3    ORIGIN FOR THE GROUP (A):  43.4764  41.2850  97.1260              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1502 T22:   0.0472                                     
REMARK   3      T33:   0.0977 T12:   0.0143                                     
REMARK   3      T13:   0.0284 T23:  -0.0145                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0016 L22:   0.0091                                     
REMARK   3      L33:   0.0030 L12:  -0.0007                                     
REMARK   3      L13:  -0.0007 L23:   0.0023                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0257 S12:  -0.0198 S13:   0.0536                       
REMARK   3      S21:   0.1070 S22:  -0.0328 S23:   0.0838                       
REMARK   3      S31:  -0.0273 S32:   0.0074 S33:   0.0026                       
REMARK   3   TLS GROUP : 11                                                     
REMARK   3    SELECTION: (CHAIN B AND RESID 94:119)                             
REMARK   3    ORIGIN FOR THE GROUP (A):  27.2337  40.0882  90.5509              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1600 T22:   0.1513                                     
REMARK   3      T33:   0.2144 T12:   0.0295                                     
REMARK   3      T13:   0.0189 T23:   0.0198                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0063 L22:   0.0013                                     
REMARK   3      L33:   0.0003 L12:  -0.0009                                     
REMARK   3      L13:   0.0027 L23:   0.0003                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0367 S12:   0.0325 S13:   0.0479                       
REMARK   3      S21:  -0.0071 S22:   0.0007 S23:   0.0181                       
REMARK   3      S31:  -0.0413 S32:  -0.0597 S33:   0.0000                       
REMARK   3   TLS GROUP : 12                                                     
REMARK   3    SELECTION: (CHAIN B AND RESID 120:189)                            
REMARK   3    ORIGIN FOR THE GROUP (A):  38.7494  34.3466  92.7314              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1200 T22:   0.0928                                     
REMARK   3      T33:   0.1009 T12:   0.0149                                     
REMARK   3      T13:   0.0110 T23:   0.0085                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0965 L22:   0.0374                                     
REMARK   3      L33:   0.0559 L12:   0.0314                                     
REMARK   3      L13:  -0.0167 L23:   0.0313                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0881 S12:   0.0771 S13:   0.0488                       
REMARK   3      S21:   0.0768 S22:  -0.0230 S23:   0.0722                       
REMARK   3      S31:   0.0101 S32:  -0.0868 S33:   0.0733                       
REMARK   3   TLS GROUP : 13                                                     
REMARK   3    SELECTION: (CHAIN B AND RESID 190:200)                            
REMARK   3    ORIGIN FOR THE GROUP (A):  37.0112  50.7486  92.1648              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1005 T22:   0.0999                                     
REMARK   3      T33:   0.2779 T12:   0.0198                                     
REMARK   3      T13:   0.0164 T23:  -0.0066                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0011 L22:   0.0083                                     
REMARK   3      L33:   0.0188 L12:   0.0012                                     
REMARK   3      L13:   0.0015 L23:  -0.0062                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0053 S12:  -0.0008 S13:   0.0069                       
REMARK   3      S21:  -0.0100 S22:  -0.0063 S23:  -0.0077                       
REMARK   3      S31:  -0.0247 S32:  -0.0007 S33:  -0.0021                       
REMARK   3   TLS GROUP : 14                                                     
REMARK   3    SELECTION: (CHAIN C AND RESID -2:3)                               
REMARK   3    ORIGIN FOR THE GROUP (A):  25.5781   8.1101  66.2622              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1567 T22:   0.1595                                     
REMARK   3      T33:   0.2195 T12:   0.0084                                     
REMARK   3      T13:  -0.0913 T23:   0.0545                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0002 L22:   0.0050                                     
REMARK   3      L33:   0.0065 L12:  -0.0005                                     
REMARK   3      L13:   0.0010 L23:  -0.0054                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0009 S12:   0.0011 S13:   0.0033                       
REMARK   3      S21:   0.0086 S22:  -0.0053 S23:  -0.0030                       
REMARK   3      S31:   0.0026 S32:  -0.0052 S33:   0.0000                       
REMARK   3   TLS GROUP : 15                                                     
REMARK   3    SELECTION: (CHAIN C AND RESID 4:42)                               
REMARK   3    ORIGIN FOR THE GROUP (A):  33.0810  19.3174  55.3832              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.0849 T22:   0.1230                                     
REMARK   3      T33:   0.0497 T12:   0.0061                                     
REMARK   3      T13:  -0.0725 T23:  -0.0141                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0506 L22:   0.0108                                     
REMARK   3      L33:   0.0607 L12:  -0.0230                                     
REMARK   3      L13:  -0.0545 L23:   0.0236                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0468 S12:   0.1111 S13:  -0.0818                       
REMARK   3      S21:  -0.0305 S22:   0.0212 S23:   0.0604                       
REMARK   3      S31:   0.0678 S32:   0.0689 S33:  -0.0157                       
REMARK   3   TLS GROUP : 16                                                     
REMARK   3    SELECTION: (CHAIN C AND RESID 43:83)                              
REMARK   3    ORIGIN FOR THE GROUP (A):  33.6858  13.3699  70.7531              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.0349 T22:   0.0430                                     
REMARK   3      T33:   0.0068 T12:   0.0092                                     
REMARK   3      T13:  -0.0614 T23:  -0.0119                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.1684 L22:   0.1273                                     
REMARK   3      L33:   0.1977 L12:   0.0778                                     
REMARK   3      L13:  -0.0086 L23:   0.0476                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0730 S12:   0.0828 S13:  -0.0010                       
REMARK   3      S21:   0.0518 S22:   0.0552 S23:   0.0022                       
REMARK   3      S31:   0.1210 S32:  -0.0231 S33:   0.1553                       
REMARK   3   TLS GROUP : 17                                                     
REMARK   3    SELECTION: (CHAIN C AND RESID 84:93)                              
REMARK   3    ORIGIN FOR THE GROUP (A):  22.3102  38.6495  54.8821              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1376 T22:   0.2798                                     
REMARK   3      T33:   0.2639 T12:   0.0569                                     
REMARK   3      T13:  -0.0665 T23:   0.1094                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0007 L22:   0.0028                                     
REMARK   3      L33:   0.0059 L12:  -0.0011                                     
REMARK   3      L13:  -0.0020 L23:   0.0042                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0135 S12:   0.0071 S13:   0.0127                       
REMARK   3      S21:   0.0018 S22:  -0.0203 S23:   0.0068                       
REMARK   3      S31:   0.0092 S32:  -0.0077 S33:  -0.0000                       
REMARK   3   TLS GROUP : 18                                                     
REMARK   3    SELECTION: (CHAIN C AND RESID 94:149)                             
REMARK   3    ORIGIN FOR THE GROUP (A):  31.8978  36.2304  70.3958              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.0979 T22:   0.0676                                     
REMARK   3      T33:   0.1112 T12:   0.0273                                     
REMARK   3      T13:   0.0167 T23:   0.0052                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0094 L22:   0.0181                                     
REMARK   3      L33:   0.0121 L12:   0.0131                                     
REMARK   3      L13:   0.0031 L23:  -0.0006                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0095 S12:   0.0301 S13:   0.0415                       
REMARK   3      S21:   0.1039 S22:   0.0433 S23:   0.0576                       
REMARK   3      S31:  -0.0761 S32:   0.0234 S33:   0.0093                       
REMARK   3   TLS GROUP : 19                                                     
REMARK   3    SELECTION: (CHAIN C AND RESID 150:189)                            
REMARK   3    ORIGIN FOR THE GROUP (A):  37.4431  31.7882  60.6685              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.0767 T22:   0.1162                                     
REMARK   3      T33:   0.0893 T12:   0.0105                                     
REMARK   3      T13:  -0.0033 T23:   0.0060                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0287 L22:   0.0260                                     
REMARK   3      L33:   0.0252 L12:   0.0228                                     
REMARK   3      L13:   0.0082 L23:   0.0040                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0410 S12:   0.1161 S13:   0.0706                       
REMARK   3      S21:   0.0238 S22:   0.0877 S23:  -0.0009                       
REMARK   3      S31:  -0.0732 S32:   0.0563 S33:   0.0367                       
REMARK   3   TLS GROUP : 20                                                     
REMARK   3    SELECTION: (CHAIN C AND RESID 190:201)                            
REMARK   3    ORIGIN FOR THE GROUP (A):  19.3256  32.7314  66.7347              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1501 T22:   0.1189                                     
REMARK   3      T33:   0.3688 T12:   0.0351                                     
REMARK   3      T13:  -0.0496 T23:   0.0346                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0011 L22:   0.0039                                     
REMARK   3      L33:   0.0013 L12:  -0.0003                                     
REMARK   3      L13:   0.0009 L23:  -0.0002                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0003 S12:   0.0004 S13:   0.0056                       
REMARK   3      S21:  -0.0057 S22:   0.0024 S23:   0.0037                       
REMARK   3      S31:  -0.0045 S32:   0.0045 S33:   0.0013                       
REMARK   3   TLS GROUP : 21                                                     
REMARK   3    SELECTION: (CHAIN D AND RESID -1:30)                              
REMARK   3    ORIGIN FOR THE GROUP (A):  33.4657  50.7968  50.1944              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1322 T22:   0.2173                                     
REMARK   3      T33:   0.0697 T12:   0.0891                                     
REMARK   3      T13:  -0.0287 T23:   0.0341                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0402 L22:   0.0517                                     
REMARK   3      L33:   0.0380 L12:   0.0255                                     
REMARK   3      L13:  -0.0284 L23:   0.0079                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0390 S12:  -0.0515 S13:  -0.0931                       
REMARK   3      S21:   0.0775 S22:   0.0365 S23:  -0.0294                       
REMARK   3      S31:  -0.0280 S32:   0.0160 S33:   0.0197                       
REMARK   3   TLS GROUP : 22                                                     
REMARK   3    SELECTION: (CHAIN D AND RESID 31:64)                              
REMARK   3    ORIGIN FOR THE GROUP (A):  28.8737  37.0086  30.7013              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1361 T22:   0.0893                                     
REMARK   3      T33:   0.1169 T12:   0.0151                                     
REMARK   3      T13:  -0.0152 T23:   0.0320                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0020 L22:   0.0066                                     
REMARK   3      L33:   0.0050 L12:  -0.0024                                     
REMARK   3      L13:   0.0047 L23:   0.0001                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0176 S12:   0.0110 S13:  -0.0641                       
REMARK   3      S21:   0.0116 S22:   0.0136 S23:  -0.0023                       
REMARK   3      S31:   0.0455 S32:   0.0018 S33:   0.0108                       
REMARK   3   TLS GROUP : 23                                                     
REMARK   3    SELECTION: (CHAIN D AND RESID 65:91)                              
REMARK   3    ORIGIN FOR THE GROUP (A):  35.8538  56.1844  43.0354              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.0929 T22:   0.1612                                     
REMARK   3      T33:   0.0947 T12:   0.0174                                     
REMARK   3      T13:  -0.0055 T23:  -0.0014                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0327 L22:   0.0085                                     
REMARK   3      L33:   0.0214 L12:  -0.0089                                     
REMARK   3      L13:   0.0245 L23:  -0.0069                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0385 S12:  -0.0699 S13:   0.0116                       
REMARK   3      S21:  -0.0072 S22:  -0.0106 S23:  -0.0319                       
REMARK   3      S31:   0.0157 S32:   0.0298 S33:  -0.0221                       
REMARK   3   TLS GROUP : 24                                                     
REMARK   3    SELECTION: (CHAIN D AND RESID 92:119)                             
REMARK   3    ORIGIN FOR THE GROUP (A):  35.6220  72.5964  36.3461              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1470 T22:   0.1842                                     
REMARK   3      T33:   0.1853 T12:  -0.0172                                     
REMARK   3      T13:   0.0161 T23:  -0.0268                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0065 L22:   0.0069                                     
REMARK   3      L33:   0.0030 L12:   0.0082                                     
REMARK   3      L13:  -0.0014 L23:  -0.0031                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0002 S12:  -0.0155 S13:   0.0609                       
REMARK   3      S21:  -0.0346 S22:   0.0187 S23:  -0.0042                       
REMARK   3      S31:  -0.0329 S32:   0.0944 S33:  -0.0002                       
REMARK   3   TLS GROUP : 25                                                     
REMARK   3    SELECTION: (CHAIN D AND RESID 120:139)                            
REMARK   3    ORIGIN FOR THE GROUP (A):  32.5983  62.7741  30.4591              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.0970 T22:   0.1274                                     
REMARK   3      T33:   0.1126 T12:  -0.0141                                     
REMARK   3      T13:   0.0274 T23:   0.0008                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0026 L22:   0.0392                                     
REMARK   3      L33:   0.0038 L12:  -0.0027                                     
REMARK   3      L13:   0.0014 L23:   0.0082                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0313 S12:  -0.0046 S13:  -0.0209                       
REMARK   3      S21:  -0.0019 S22:   0.0559 S23:   0.0122                       
REMARK   3      S31:  -0.0037 S32:  -0.0057 S33:   0.0306                       
REMARK   3   TLS GROUP : 26                                                     
REMARK   3    SELECTION: (CHAIN D AND RESID 140:190)                            
REMARK   3    ORIGIN FOR THE GROUP (A):  27.8998  60.9300  41.0895              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.0832 T22:   0.1157                                     
REMARK   3      T33:   0.0757 T12:   0.0145                                     
REMARK   3      T13:  -0.0050 T23:   0.0021                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0104 L22:   0.0792                                     
REMARK   3      L33:   0.1371 L12:  -0.0037                                     
REMARK   3      L13:  -0.0018 L23:   0.0310                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0065 S12:  -0.0708 S13:  -0.0039                       
REMARK   3      S21:   0.0384 S22:   0.0977 S23:  -0.0149                       
REMARK   3      S31:  -0.0137 S32:   0.0068 S33:   0.1061                       
REMARK   3   TLS GROUP : 27                                                     
REMARK   3    SELECTION: (CHAIN D AND RESID 191:202)                            
REMARK   3    ORIGIN FOR THE GROUP (A):  45.7717  60.8801  35.6175              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1096 T22:   0.2357                                     
REMARK   3      T33:   0.2330 T12:  -0.0012                                     
REMARK   3      T13:   0.0256 T23:  -0.0160                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0007 L22:   0.0029                                     
REMARK   3      L33:   0.0008 L12:  -0.0013                                     
REMARK   3      L13:  -0.0002 L23:   0.0008                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0189 S12:  -0.0051 S13:  -0.0228                       
REMARK   3      S21:   0.0106 S22:  -0.0022 S23:  -0.0052                       
REMARK   3      S31:   0.0152 S32:   0.0113 S33:   0.0002                       
REMARK   3   TLS GROUP : 28                                                     
REMARK   3    SELECTION: (CHAIN E AND RESID -1:28)                              
REMARK   3    ORIGIN FOR THE GROUP (A):  71.1783  67.9824 107.1431              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.3591 T22:   0.1146                                     
REMARK   3      T33:   0.0745 T12:   0.0835                                     
REMARK   3      T13:   0.0633 T23:   0.0906                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0091 L22:   0.0037                                     
REMARK   3      L33:   0.0025 L12:  -0.0031                                     
REMARK   3      L13:   0.0017 L23:  -0.0016                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0065 S12:   0.0393 S13:   0.0212                       
REMARK   3      S21:  -0.0756 S22:  -0.0501 S23:  -0.0229                       
REMARK   3      S31:   0.0200 S32:   0.0280 S33:  -0.0440                       
REMARK   3   TLS GROUP : 29                                                     
REMARK   3    SELECTION: (CHAIN E AND RESID 29:59)                              
REMARK   3    ORIGIN FOR THE GROUP (A):  58.0209  64.2609 126.3812              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1065 T22:   0.0754                                     
REMARK   3      T33:   0.0916 T12:   0.0192                                     
REMARK   3      T13:  -0.0109 T23:  -0.0072                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0011 L22:   0.0032                                     
REMARK   3      L33:   0.0113 L12:   0.0018                                     
REMARK   3      L13:  -0.0045 L23:  -0.0075                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0141 S12:  -0.0097 S13:   0.0032                       
REMARK   3      S21:  -0.0529 S22:   0.0259 S23:   0.0541                       
REMARK   3      S31:  -0.0184 S32:  -0.0503 S33:  -0.0001                       
REMARK   3   TLS GROUP : 30                                                     
REMARK   3    SELECTION: (CHAIN E AND RESID 60:83)                              
REMARK   3    ORIGIN FOR THE GROUP (A):  70.9540  66.6029 119.8516              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1073 T22:  -0.0205                                     
REMARK   3      T33:   0.0494 T12:   0.0128                                     
REMARK   3      T13:   0.0564 T23:   0.0503                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0307 L22:   0.0362                                     
REMARK   3      L33:   0.0829 L12:  -0.0325                                     
REMARK   3      L13:   0.0513 L23:  -0.0477                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0046 S12:   0.0420 S13:   0.0642                       
REMARK   3      S21:  -0.0928 S22:  -0.0767 S23:  -0.0842                       
REMARK   3      S31:  -0.0158 S32:   0.0241 S33:  -0.0915                       
REMARK   3   TLS GROUP : 31                                                     
REMARK   3    SELECTION: (CHAIN E AND RESID 84:119)                             
REMARK   3    ORIGIN FOR THE GROUP (A):  92.1280  71.1022 116.7420              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1633 T22:   0.1276                                     
REMARK   3      T33:   0.3126 T12:  -0.0998                                     
REMARK   3      T13:   0.0593 T23:   0.0358                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0307 L22:   0.0025                                     
REMARK   3      L33:   0.0168 L12:   0.0105                                     
REMARK   3      L13:  -0.0269 L23:  -0.0052                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0465 S12:  -0.0017 S13:   0.0504                       
REMARK   3      S21:  -0.0352 S22:  -0.0236 S23:  -0.0082                       
REMARK   3      S31:  -0.0507 S32:   0.0783 S33:  -0.0390                       
REMARK   3   TLS GROUP : 32                                                     
REMARK   3    SELECTION: (CHAIN E AND RESID 120:178)                            
REMARK   3    ORIGIN FOR THE GROUP (A):  80.9751  63.0092 121.1578              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.0859 T22:   0.0183                                     
REMARK   3      T33:   0.1427 T12:  -0.0161                                     
REMARK   3      T13:   0.0324 T23:   0.0133                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0881 L22:   0.0578                                     
REMARK   3      L33:   0.0214 L12:  -0.0634                                     
REMARK   3      L13:   0.0136 L23:  -0.0029                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0432 S12:  -0.0444 S13:   0.0408                       
REMARK   3      S21:  -0.0157 S22:  -0.0099 S23:  -0.1687                       
REMARK   3      S31:   0.0373 S32:   0.0299 S33:  -0.0715                       
REMARK   3   TLS GROUP : 33                                                     
REMARK   3    SELECTION: (CHAIN E AND RESID 179:200)                            
REMARK   3    ORIGIN FOR THE GROUP (A):  85.2025  72.2437 114.2794              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1952 T22:   0.1083                                     
REMARK   3      T33:   0.3223 T12:  -0.0779                                     
REMARK   3      T13:   0.1149 T23:   0.0630                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0314 L22:   0.0132                                     
REMARK   3      L33:   0.0616 L12:   0.0198                                     
REMARK   3      L13:   0.0176 L23:   0.0039                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0777 S12:   0.0220 S13:   0.0518                       
REMARK   3      S21:  -0.0476 S22:  -0.0521 S23:  -0.0269                       
REMARK   3      S31:   0.0358 S32:   0.0751 S33:  -0.0797                       
REMARK   3   TLS GROUP : 34                                                     
REMARK   3    SELECTION: (CHAIN F AND RESID 1:24)                               
REMARK   3    ORIGIN FOR THE GROUP (A):  43.2587  65.6298 104.9737              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.5252 T22:   0.0964                                     
REMARK   3      T33:   0.0816 T12:  -0.0825                                     
REMARK   3      T13:  -0.1996 T23:   0.1527                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0079 L22:   0.0034                                     
REMARK   3      L33:   0.0039 L12:  -0.0029                                     
REMARK   3      L13:  -0.0039 L23:  -0.0015                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0226 S12:  -0.0138 S13:  -0.0125                       
REMARK   3      S21:   0.0693 S22:  -0.0238 S23:  -0.0083                       
REMARK   3      S31:  -0.0042 S32:   0.0085 S33:  -0.0508                       
REMARK   3   TLS GROUP : 35                                                     
REMARK   3    SELECTION: (CHAIN F AND RESID 25:48)                              
REMARK   3    ORIGIN FOR THE GROUP (A):  32.0296  70.2433  92.2868              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.2151 T22:   0.1084                                     
REMARK   3      T33:   0.1614 T12:  -0.0762                                     
REMARK   3      T13:   0.0280 T23:   0.0086                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0032 L22:   0.0203                                     
REMARK   3      L33:   0.0054 L12:   0.0042                                     
REMARK   3      L13:  -0.0036 L23:  -0.0023                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0415 S12:   0.0041 S13:   0.0041                       
REMARK   3      S21:   0.1024 S22:   0.0388 S23:  -0.0009                       
REMARK   3      S31:  -0.0130 S32:  -0.0240 S33:   0.0223                       
REMARK   3   TLS GROUP : 36                                                     
REMARK   3    SELECTION: (CHAIN F AND RESID 49:70)                              
REMARK   3    ORIGIN FOR THE GROUP (A):  31.1203  73.6853  79.7247              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.0728 T22:   0.0944                                     
REMARK   3      T33:   0.0680 T12:   0.0069                                     
REMARK   3      T13:  -0.0089 T23:  -0.0106                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0122 L22:   0.0089                                     
REMARK   3      L33:   0.0012 L12:  -0.0026                                     
REMARK   3      L13:  -0.0025 L23:  -0.0021                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0141 S12:   0.0226 S13:  -0.0207                       
REMARK   3      S21:   0.0414 S22:  -0.0169 S23:   0.0312                       
REMARK   3      S31:   0.0046 S32:  -0.0206 S33:   0.0010                       
REMARK   3   TLS GROUP : 37                                                     
REMARK   3    SELECTION: (CHAIN F AND RESID 71:102)                             
REMARK   3    ORIGIN FOR THE GROUP (A):  54.3869  60.7129  96.6046              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.3579 T22:  -0.0029                                     
REMARK   3      T33:   0.1956 T12:   0.0318                                     
REMARK   3      T13:  -0.1844 T23:   0.0089                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0130 L22:   0.0436                                     
REMARK   3      L33:   0.0715 L12:  -0.0037                                     
REMARK   3      L13:  -0.0030 L23:  -0.0530                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0854 S12:  -0.0004 S13:  -0.0805                       
REMARK   3      S21:   0.0925 S22:   0.0629 S23:  -0.0854                       
REMARK   3      S31:   0.0835 S32:   0.0383 S33:   0.0836                       
REMARK   3   TLS GROUP : 38                                                     
REMARK   3    SELECTION: (CHAIN F AND RESID 103:180)                            
REMARK   3    ORIGIN FOR THE GROUP (A):  54.5641  71.6450  91.1840              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1475 T22:  -0.1105                                     
REMARK   3      T33:  -0.1252 T12:  -0.0271                                     
REMARK   3      T13:  -0.1752 T23:  -0.2305                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0429 L22:   0.0457                                     
REMARK   3      L33:   0.0036 L12:   0.0251                                     
REMARK   3      L13:  -0.0067 L23:   0.0036                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.1612 S12:   0.0707 S13:  -0.1029                       
REMARK   3      S21:   0.0410 S22:  -0.0158 S23:  -0.0729                       
REMARK   3      S31:   0.1111 S32:   0.0967 S33:   0.1048                       
REMARK   3   TLS GROUP : 39                                                     
REMARK   3    SELECTION: (CHAIN F AND RESID 181:202)                            
REMARK   3    ORIGIN FOR THE GROUP (A):  55.2174  60.3310  94.9587              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.3370 T22:   0.0985                                     
REMARK   3      T33:   0.2471 T12:   0.0682                                     
REMARK   3      T13:  -0.2498 T23:  -0.0074                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0019 L22:   0.0112                                     
REMARK   3      L33:   0.0037 L12:  -0.0004                                     
REMARK   3      L13:  -0.0020 L23:   0.0028                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0003 S12:  -0.0051 S13:  -0.0254                       
REMARK   3      S21:   0.0217 S22:  -0.0020 S23:  -0.0056                       
REMARK   3      S31:  -0.0111 S32:  -0.0043 S33:  -0.0288                       
REMARK   3   TLS GROUP : 40                                                     
REMARK   3    SELECTION: (CHAIN G AND RESID -1:37)                              
REMARK   3    ORIGIN FOR THE GROUP (A):  62.3533  59.9279  49.1723              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.0635 T22:   0.1879                                     
REMARK   3      T33:   0.0399 T12:   0.1174                                     
REMARK   3      T13:   0.0991 T23:   0.0280                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0322 L22:   0.0140                                     
REMARK   3      L33:   0.0387 L12:   0.0133                                     
REMARK   3      L13:   0.0117 L23:   0.0197                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.1278 S12:  -0.1559 S13:  -0.1026                       
REMARK   3      S21:   0.0672 S22:  -0.0086 S23:   0.0414                       
REMARK   3      S31:   0.0402 S32:   0.0241 S33:  -0.1205                       
REMARK   3   TLS GROUP : 41                                                     
REMARK   3    SELECTION: (CHAIN G AND RESID 38:60)                              
REMARK   3    ORIGIN FOR THE GROUP (A):  64.8946  73.9408  26.7000              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1329 T22:   0.0791                                     
REMARK   3      T33:   0.0915 T12:   0.0120                                     
REMARK   3      T13:   0.0105 T23:  -0.0133                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0002 L22:   0.0015                                     
REMARK   3      L33:   0.0025 L12:   0.0011                                     
REMARK   3      L13:  -0.0013 L23:   0.0015                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0045 S12:  -0.0210 S13:   0.0233                       
REMARK   3      S21:   0.0159 S22:   0.0029 S23:  -0.0206                       
REMARK   3      S31:  -0.0159 S32:  -0.0085 S33:  -0.0000                       
REMARK   3   TLS GROUP : 42                                                     
REMARK   3    SELECTION: (CHAIN G AND RESID 61:102)                             
REMARK   3    ORIGIN FOR THE GROUP (A):  58.2239  50.1504  41.0918              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:  -0.0523 T22:   0.0724                                     
REMARK   3      T33:   0.1733 T12:  -0.0112                                     
REMARK   3      T13:   0.0869 T23:   0.0446                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0017 L22:   0.0080                                     
REMARK   3      L33:   0.0079 L12:   0.0031                                     
REMARK   3      L13:   0.0031 L23:   0.0053                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0458 S12:  -0.0851 S13:  -0.1515                       
REMARK   3      S21:   0.0368 S22:  -0.0012 S23:   0.1178                       
REMARK   3      S31:   0.0648 S32:  -0.0650 S33:  -0.0205                       
REMARK   3   TLS GROUP : 43                                                     
REMARK   3    SELECTION: (CHAIN G AND RESID 103:136)                            
REMARK   3    ORIGIN FOR THE GROUP (A):  63.3820  41.4046  35.4438              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.0168 T22:  -0.0059                                     
REMARK   3      T33:   0.1862 T12:  -0.0494                                     
REMARK   3      T13:   0.0464 T23:   0.0159                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0192 L22:   0.0050                                     
REMARK   3      L33:   0.0033 L12:   0.0100                                     
REMARK   3      L13:   0.0110 L23:   0.0059                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0417 S12:  -0.0084 S13:  -0.0911                       
REMARK   3      S21:  -0.0176 S22:  -0.0051 S23:   0.0395                       
REMARK   3      S31:   0.0576 S32:  -0.0184 S33:  -0.0519                       
REMARK   3   TLS GROUP : 44                                                     
REMARK   3    SELECTION: (CHAIN G AND RESID 137:178)                            
REMARK   3    ORIGIN FOR THE GROUP (A):  67.5550  49.1787  39.0425              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.0281 T22:   0.1392                                     
REMARK   3      T33:   0.1673 T12:  -0.0017                                     
REMARK   3      T13:   0.0559 T23:   0.0724                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0274 L22:   0.0465                                     
REMARK   3      L33:   0.0553 L12:  -0.0180                                     
REMARK   3      L13:  -0.0128 L23:   0.0062                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0694 S12:  -0.0542 S13:  -0.1278                       
REMARK   3      S21:  -0.0003 S22:  -0.0344 S23:   0.0488                       
REMARK   3      S31:   0.0609 S32:   0.0566 S33:  -0.1024                       
REMARK   3   TLS GROUP : 45                                                     
REMARK   3    SELECTION: (CHAIN G AND RESID 179:201)                            
REMARK   3    ORIGIN FOR THE GROUP (A):  56.6011  44.4975  43.4235              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1880 T22:   0.2573                                     
REMARK   3      T33:   0.4458 T12:  -0.0630                                     
REMARK   3      T13:   0.1243 T23:   0.1563                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0272 L22:   0.0444                                     
REMARK   3      L33:   0.0373 L12:   0.0303                                     
REMARK   3      L13:  -0.0053 L23:   0.0198                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0553 S12:  -0.0245 S13:  -0.0340                       
REMARK   3      S21:   0.0415 S22:  -0.0642 S23:   0.0685                       
REMARK   3      S31:   0.0903 S32:   0.0278 S33:  -0.0949                       
REMARK   3   TLS GROUP : 46                                                     
REMARK   3    SELECTION: (CHAIN H AND RESID 1:40)                               
REMARK   3    ORIGIN FOR THE GROUP (A):  61.4666  30.6616  56.7189              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.0434 T22:   0.3840                                     
REMARK   3      T33:   0.1295 T12:  -0.1684                                     
REMARK   3      T13:   0.0725 T23:  -0.0576                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0195 L22:   0.0056                                     
REMARK   3      L33:   0.0149 L12:   0.0018                                     
REMARK   3      L13:  -0.0012 L23:   0.0078                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0189 S12:   0.1518 S13:   0.0322                       
REMARK   3      S21:  -0.0067 S22:   0.0066 S23:  -0.0051                       
REMARK   3      S31:  -0.0264 S32:   0.0112 S33:  -0.0321                       
REMARK   3   TLS GROUP : 47                                                     
REMARK   3    SELECTION: (CHAIN H AND RESID 41:83)                              
REMARK   3    ORIGIN FOR THE GROUP (A):  59.5353  35.3721  72.4827              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:  -0.0114 T22:   0.1887                                     
REMARK   3      T33:   0.1040 T12:  -0.0969                                     
REMARK   3      T13:   0.0018 T23:  -0.0546                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0674 L22:   0.0343                                     
REMARK   3      L33:   0.0935 L12:   0.0237                                     
REMARK   3      L13:  -0.0063 L23:  -0.0481                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0073 S12:   0.1589 S13:   0.0119                       
REMARK   3      S21:   0.0295 S22:   0.0691 S23:  -0.0521                       
REMARK   3      S31:  -0.0874 S32:   0.0806 S33:   0.0634                       
REMARK   3   TLS GROUP : 48                                                     
REMARK   3    SELECTION: (CHAIN H AND RESID 84:93)                              
REMARK   3    ORIGIN FOR THE GROUP (A):  72.0230  11.3905  55.0246              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1118 T22:   0.3597                                     
REMARK   3      T33:   0.2662 T12:   0.0868                                     
REMARK   3      T13:   0.0046 T23:  -0.1520                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0048 L22:   0.0008                                     
REMARK   3      L33:   0.0017 L12:  -0.0020                                     
REMARK   3      L13:  -0.0031 L23:   0.0007                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0001 S12:   0.0006 S13:   0.0046                       
REMARK   3      S21:  -0.0014 S22:  -0.0074 S23:  -0.0061                       
REMARK   3      S31:   0.0037 S32:   0.0022 S33:  -0.0020                       
REMARK   3   TLS GROUP : 49                                                     
REMARK   3    SELECTION: (CHAIN H AND RESID 94:119)                             
REMARK   3    ORIGIN FOR THE GROUP (A):  63.3485   5.9041  67.1223              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.1424 T22:   0.2108                                     
REMARK   3      T33:   0.2186 T12:   0.1066                                     
REMARK   3      T13:  -0.0699 T23:  -0.1953                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0280 L22:   0.0145                                     
REMARK   3      L33:   0.0124 L12:  -0.0207                                     
REMARK   3      L13:   0.0156 L23:  -0.0130                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0229 S12:   0.0071 S13:  -0.0374                       
REMARK   3      S21:   0.0459 S22:   0.0376 S23:  -0.0761                       
REMARK   3      S31:   0.0296 S32:   0.0496 S33:   0.0196                       
REMARK   3   TLS GROUP : 50                                                     
REMARK   3    SELECTION: (CHAIN H AND RESID 120:169)                            
REMARK   3    ORIGIN FOR THE GROUP (A):  59.1565  18.6403  70.7824              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.0045 T22:   0.2166                                     
REMARK   3      T33:   0.0564 T12:   0.0116                                     
REMARK   3      T13:  -0.0613 T23:  -0.0958                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0461 L22:   0.0832                                     
REMARK   3      L33:   0.0312 L12:   0.0114                                     
REMARK   3      L13:   0.0164 L23:  -0.0317                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0152 S12:   0.0150 S13:   0.0110                       
REMARK   3      S21:   0.0615 S22:   0.1995 S23:  -0.0684                       
REMARK   3      S31:   0.0469 S32:   0.0618 S33:   0.2010                       
REMARK   3   TLS GROUP : 51                                                     
REMARK   3    SELECTION: (CHAIN H AND RESID 170:202)                            
REMARK   3    ORIGIN FOR THE GROUP (A):  62.2101  15.7420  59.8581              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.0940 T22:   0.3591                                     
REMARK   3      T33:   0.1472 T12:   0.0273                                     
REMARK   3      T13:  -0.0296 T23:  -0.2715                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   0.0032 L22:   0.0056                                     
REMARK   3      L33:   0.0014 L12:   0.0014                                     
REMARK   3      L13:  -0.0016 L23:  -0.0043                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.0047 S12:   0.0520 S13:  -0.0336                       
REMARK   3      S21:  -0.0057 S22:   0.0253 S23:  -0.0535                       
REMARK   3      S31:   0.0266 S32:   0.0309 S33:  -0.0127                       
REMARK   3                                                                      
REMARK   3  NCS DETAILS                                                         
REMARK   3   NUMBER OF NCS GROUPS : 1                                           
REMARK   3   NCS GROUP : 1                                                      
REMARK   3                                                                      
REMARK   3  OTHER REFINEMENT REMARKS: MNSOD REFINEMENT CONVERGED TO R- -WORK    
REMARK   3  AND R-FREE OF 0.1759 AND 0.2153, RESPECTIVELY, USING A THIN-        
REMARK   3  SHELLS R-FREE SET WITH 2149 REFLECTIONS. THEN A LAST REFINEMENT     
REMARK   3  CYCLE WAS PERFORMED USING THE FULL DATA SET IN ORDER TO OBTAIN      
REMARK   3  THE FINAL MNSOD MODEL.                                              
REMARK   4                                                                      
REMARK   4 4C7U COMPLIES WITH FORMAT V. 3.30, 13-JUL-11                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBE ON 25-SEP-13.                  
REMARK 100 THE DEPOSITION ID IS D_1290058381.                                   
REMARK 200                                                                      
REMARK 200 EXPERIMENTAL DETAILS                                                 
REMARK 200  EXPERIMENT TYPE                : X-RAY DIFFRACTION                  
REMARK 200  DATE OF DATA COLLECTION        : 20-JUN-13                          
REMARK 200  TEMPERATURE           (KELVIN) : 100                                
REMARK 200  PH                             : NULL                               
REMARK 200  NUMBER OF CRYSTALS USED        : 1                                  
REMARK 200                                                                      
REMARK 200  SYNCHROTRON              (Y/N) : Y                                  
REMARK 200  RADIATION SOURCE               : ESRF                               
REMARK 200  BEAMLINE                       : ID29                               
REMARK 200  X-RAY GENERATOR MODEL          : NULL                               
REMARK 200  MONOCHROMATIC OR LAUE    (M/L) : M                                  
REMARK 200  WAVELENGTH OR RANGE        (A) : 0.9611                             
REMARK 200  MONOCHROMATOR                  : SI(111)                            
REMARK 200  OPTICS                         : TOROIDAL MIRROR                    
REMARK 200                                                                      
REMARK 200  DETECTOR TYPE                  : PIXEL                              
REMARK 200  DETECTOR MANUFACTURER          : DECTRIS PILATUS 6M                 
REMARK 200  INTENSITY-INTEGRATION SOFTWARE : XDS                                
REMARK 200  DATA SCALING SOFTWARE          : XDS                                
REMARK 200                                                                      
REMARK 200  NUMBER OF UNIQUE REFLECTIONS   : 98683                              
REMARK 200  RESOLUTION RANGE HIGH      (A) : 1.950                              
REMARK 200  RESOLUTION RANGE LOW       (A) : 53.980                             
REMARK 200  REJECTION CRITERIA  (SIGMA(I)) : 0.000                              
REMARK 200                                                                      
REMARK 200 OVERALL.                                                             
REMARK 200  COMPLETENESS FOR RANGE     (%) : 92.9                               
REMARK 200  DATA REDUNDANCY                : 1.740                              
REMARK 200  R MERGE                    (I) : 0.07000                            
REMARK 200  R SYM                      (I) : NULL                               
REMARK 200  <I/SIGMA(I)> FOR THE DATA SET  : 7.6400                             
REMARK 200                                                                      
REMARK 200 IN THE HIGHEST RESOLUTION SHELL.                                     
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 1.95                     
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE LOW  (A) : 2.07                     
REMARK 200  COMPLETENESS FOR SHELL     (%) : 92.3                               
REMARK 200  DATA REDUNDANCY IN SHELL       : 1.45                               
REMARK 200  R MERGE FOR SHELL          (I) : 0.57000                            
REMARK 200  R SYM FOR SHELL            (I) : NULL                               
REMARK 200  <I/SIGMA(I)> FOR SHELL         : 1.090                              
REMARK 200                                                                      
REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH                              
REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT        
REMARK 200 SOFTWARE USED: PHASER                                                
REMARK 200 STARTING MODEL: PDB ENTRIES 3AK2 1GV3 1IX9 1LUW 1COJ                 
REMARK 200                                                                      
REMARK 200 REMARK: NONE                                                         
REMARK 280                                                                      
REMARK 280 CRYSTAL                                                              
REMARK 280 SOLVENT CONTENT, VS   (%): 40.70                                     
REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.07                     
REMARK 280                                                                      
REMARK 280 CRYSTALLIZATION CONDITIONS: 0.2 M SODIUM FORMATE, 20 % PEG 3350,     
REMARK 280  VAPOR DIFFUSION, HANGING DROP, TEMPERATURE 277 K                    
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY                                            
REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 1                              
REMARK 290                                                                      
REMARK 290      SYMOP   SYMMETRY                                                
REMARK 290     NNNMMM   OPERATOR                                                
REMARK 290       1555   X,Y,Z                                                   
REMARK 290                                                                      
REMARK 290     WHERE NNN -> OPERATOR NUMBER                                     
REMARK 290           MMM -> TRANSLATION VECTOR                                  
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS                            
REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM             
REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY                
REMARK 290 RELATED MOLECULES.                                                   
REMARK 290   SMTRY1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 290                                                                      
REMARK 290 REMARK: NULL                                                         
REMARK 300                                                                      
REMARK 300 BIOMOLECULE: 1, 2, 3, 4, 5                                           
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM                
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN                  
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON               
REMARK 300 BURIED SURFACE AREA.                                                 
REMARK 350                                                                      
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN           
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE                
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS          
REMARK 350 GIVEN BELOW.  BOTH NON-CRYSTALLOGRAPHIC AND                          
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.                               
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 1                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TETRAMERIC                        
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TETRAMERIC                 
REMARK 350 SOFTWARE USED: PISA                                                  
REMARK 350 TOTAL BURIED SURFACE AREA: 8440 ANGSTROM**2                          
REMARK 350 SURFACE AREA OF THE COMPLEX: 31130 ANGSTROM**2                       
REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -57.7 KCAL/MOL                        
REMARK 350 APPLY THE FOLLOWING TO CHAINS: F                                     
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000       -0.15494            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000      -59.18080            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 350 APPLY THE FOLLOWING TO CHAINS: B, C, H                               
REMARK 350   BIOMT1   2  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   2  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   2  0.000000  0.000000  1.000000        0.00000            
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 2                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TETRAMERIC                        
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TETRAMERIC                 
REMARK 350 SOFTWARE USED: PISA                                                  
REMARK 350 TOTAL BURIED SURFACE AREA: 8530 ANGSTROM**2                          
REMARK 350 SURFACE AREA OF THE COMPLEX: 31320 ANGSTROM**2                       
REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -58.4 KCAL/MOL                        
REMARK 350 APPLY THE FOLLOWING TO CHAINS: G                                     
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000       -0.96114            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000       -1.03400            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000      107.97077            
REMARK 350 APPLY THE FOLLOWING TO CHAINS: D                                     
REMARK 350   BIOMT1   2  1.000000  0.000000  0.000000       57.99086            
REMARK 350   BIOMT2   2  0.000000  1.000000  0.000000       -1.03400            
REMARK 350   BIOMT3   2  0.000000  0.000000  1.000000      107.97077            
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, E                                  
REMARK 350   BIOMT1   3  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   3  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   3  0.000000  0.000000  1.000000        0.00000            
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 3                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TETRAMERIC                        
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TETRAMERIC                 
REMARK 350 SOFTWARE USED: PISA                                                  
REMARK 350 TOTAL BURIED SURFACE AREA: 8440 ANGSTROM**2                          
REMARK 350 SURFACE AREA OF THE COMPLEX: 31130 ANGSTROM**2                       
REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -57.7 KCAL/MOL                        
REMARK 350 APPLY THE FOLLOWING TO CHAINS: F                                     
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 350 APPLY THE FOLLOWING TO CHAINS: B, C, H                               
REMARK 350   BIOMT1   2  1.000000  0.000000  0.000000        0.15494            
REMARK 350   BIOMT2   2  0.000000  1.000000  0.000000       59.18080            
REMARK 350   BIOMT3   2  0.000000  0.000000  1.000000        0.00000            
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 4                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TETRAMERIC                        
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TETRAMERIC                 
REMARK 350 SOFTWARE USED: PISA                                                  
REMARK 350 TOTAL BURIED SURFACE AREA: 8530 ANGSTROM**2                          
REMARK 350 SURFACE AREA OF THE COMPLEX: 31320 ANGSTROM**2                       
REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -58.4 KCAL/MOL                        
REMARK 350 APPLY THE FOLLOWING TO CHAINS: G                                     
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 350 APPLY THE FOLLOWING TO CHAINS: D                                     
REMARK 350   BIOMT1   2  1.000000  0.000000  0.000000       58.95200            
REMARK 350   BIOMT2   2  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   2  0.000000  0.000000  1.000000        0.00000            
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, E                                  
REMARK 350   BIOMT1   3  1.000000  0.000000  0.000000        0.96114            
REMARK 350   BIOMT2   3  0.000000  1.000000  0.000000        1.03400            
REMARK 350   BIOMT3   3  0.000000  0.000000  1.000000     -107.97077            
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 5                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TETRAMERIC                        
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TETRAMERIC                 
REMARK 350 SOFTWARE USED: PISA                                                  
REMARK 350 TOTAL BURIED SURFACE AREA: 8530 ANGSTROM**2                          
REMARK 350 SURFACE AREA OF THE COMPLEX: 31320 ANGSTROM**2                       
REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -58.4 KCAL/MOL                        
REMARK 350 APPLY THE FOLLOWING TO CHAINS: D                                     
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 350 APPLY THE FOLLOWING TO CHAINS: G                                     
REMARK 350   BIOMT1   2  1.000000  0.000000  0.000000      -58.95200            
REMARK 350   BIOMT2   2  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   2  0.000000  0.000000  1.000000        0.00000            
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, E                                  
REMARK 350   BIOMT1   3  1.000000  0.000000  0.000000      -57.99086            
REMARK 350   BIOMT2   3  0.000000  1.000000  0.000000        1.03400            
REMARK 350   BIOMT3   3  0.000000  0.000000  1.000000     -107.97077            
REMARK 465                                                                      
REMARK 465 MISSING RESIDUES                                                     
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE                       
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)                
REMARK 465                                                                      
REMARK 465   M RES C SSSEQI                                                     
REMARK 465     MET A   -23                                                      
REMARK 465     SER A   -22                                                      
REMARK 465     TYR A   -21                                                      
REMARK 465     TYR A   -20                                                      
REMARK 465     HIS A   -19                                                      
REMARK 465     HIS A   -18                                                      
REMARK 465     HIS A   -17                                                      
REMARK 465     HIS A   -16                                                      
REMARK 465     HIS A   -15                                                      
REMARK 465     HIS A   -14                                                      
REMARK 465     LEU A   -13                                                      
REMARK 465     GLU A   -12                                                      
REMARK 465     SER A   -11                                                      
REMARK 465     THR A   -10                                                      
REMARK 465     SER A    -9                                                      
REMARK 465     LEU A    -8                                                      
REMARK 465     TYR A    -7                                                      
REMARK 465     LYS A    -6                                                      
REMARK 465     LYS A    -5                                                      
REMARK 465     ALA A    -4                                                      
REMARK 465     GLY A    -3                                                      
REMARK 465     PHE A    -2                                                      
REMARK 465     MET B   -23                                                      
REMARK 465     SER B   -22                                                      
REMARK 465     TYR B   -21                                                      
REMARK 465     TYR B   -20                                                      
REMARK 465     HIS B   -19                                                      
REMARK 465     HIS B   -18                                                      
REMARK 465     HIS B   -17                                                      
REMARK 465     HIS B   -16                                                      
REMARK 465     HIS B   -15                                                      
REMARK 465     HIS B   -14                                                      
REMARK 465     LEU B   -13                                                      
REMARK 465     GLU B   -12                                                      
REMARK 465     SER B   -11                                                      
REMARK 465     THR B   -10                                                      
REMARK 465     SER B    -9                                                      
REMARK 465     LEU B    -8                                                      
REMARK 465     TYR B    -7                                                      
REMARK 465     LYS B    -6                                                      
REMARK 465     LYS B    -5                                                      
REMARK 465     ALA B    -4                                                      
REMARK 465     GLY B    -3                                                      
REMARK 465     ASN B   201                                                      
REMARK 465     ASN B   202                                                      
REMARK 465     MET C   -23                                                      
REMARK 465     SER C   -22                                                      
REMARK 465     TYR C   -21                                                      
REMARK 465     TYR C   -20                                                      
REMARK 465     HIS C   -19                                                      
REMARK 465     HIS C   -18                                                      
REMARK 465     HIS C   -17                                                      
REMARK 465     HIS C   -16                                                      
REMARK 465     HIS C   -15                                                      
REMARK 465     HIS C   -14                                                      
REMARK 465     LEU C   -13                                                      
REMARK 465     GLU C   -12                                                      
REMARK 465     SER C   -11                                                      
REMARK 465     THR C   -10                                                      
REMARK 465     SER C    -9                                                      
REMARK 465     LEU C    -8                                                      
REMARK 465     TYR C    -7                                                      
REMARK 465     LYS C    -6                                                      
REMARK 465     LYS C    -5                                                      
REMARK 465     ALA C    -4                                                      
REMARK 465     GLY C    -3                                                      
REMARK 465     ASN C   202                                                      
REMARK 465     MET D   -23                                                      
REMARK 465     SER D   -22                                                      
REMARK 465     TYR D   -21                                                      
REMARK 465     TYR D   -20                                                      
REMARK 465     HIS D   -19                                                      
REMARK 465     HIS D   -18                                                      
REMARK 465     HIS D   -17                                                      
REMARK 465     HIS D   -16                                                      
REMARK 465     HIS D   -15                                                      
REMARK 465     HIS D   -14                                                      
REMARK 465     LEU D   -13                                                      
REMARK 465     GLU D   -12                                                      
REMARK 465     SER D   -11                                                      
REMARK 465     THR D   -10                                                      
REMARK 465     SER D    -9                                                      
REMARK 465     LEU D    -8                                                      
REMARK 465     TYR D    -7                                                      
REMARK 465     LYS D    -6                                                      
REMARK 465     LYS D    -5                                                      
REMARK 465     ALA D    -4                                                      
REMARK 465     GLY D    -3                                                      
REMARK 465     PHE D    -2                                                      
REMARK 465     MET E   -23                                                      
REMARK 465     SER E   -22                                                      
REMARK 465     TYR E   -21                                                      
REMARK 465     TYR E   -20                                                      
REMARK 465     HIS E   -19                                                      
REMARK 465     HIS E   -18                                                      
REMARK 465     HIS E   -17                                                      
REMARK 465     HIS E   -16                                                      
REMARK 465     HIS E   -15                                                      
REMARK 465     HIS E   -14                                                      
REMARK 465     LEU E   -13                                                      
REMARK 465     GLU E   -12                                                      
REMARK 465     SER E   -11                                                      
REMARK 465     THR E   -10                                                      
REMARK 465     SER E    -9                                                      
REMARK 465     LEU E    -8                                                      
REMARK 465     TYR E    -7                                                      
REMARK 465     LYS E    -6                                                      
REMARK 465     LYS E    -5                                                      
REMARK 465     ALA E    -4                                                      
REMARK 465     GLY E    -3                                                      
REMARK 465     PHE E    -2                                                      
REMARK 465     ASN E   201                                                      
REMARK 465     ASN E   202                                                      
REMARK 465     MET F   -23                                                      
REMARK 465     SER F   -22                                                      
REMARK 465     TYR F   -21                                                      
REMARK 465     TYR F   -20                                                      
REMARK 465     HIS F   -19                                                      
REMARK 465     HIS F   -18                                                      
REMARK 465     HIS F   -17                                                      
REMARK 465     HIS F   -16                                                      
REMARK 465     HIS F   -15                                                      
REMARK 465     HIS F   -14                                                      
REMARK 465     LEU F   -13                                                      
REMARK 465     GLU F   -12                                                      
REMARK 465     SER F   -11                                                      
REMARK 465     THR F   -10                                                      
REMARK 465     SER F    -9                                                      
REMARK 465     LEU F    -8                                                      
REMARK 465     TYR F    -7                                                      
REMARK 465     LYS F    -6                                                      
REMARK 465     LYS F    -5                                                      
REMARK 465     ALA F    -4                                                      
REMARK 465     GLY F    -3                                                      
REMARK 465     PHE F    -2                                                      
REMARK 465     MET F    -1                                                      
REMARK 465     MET G   -23                                                      
REMARK 465     SER G   -22                                                      
REMARK 465     TYR G   -21                                                      
REMARK 465     TYR G   -20                                                      
REMARK 465     HIS G   -19                                                      
REMARK 465     HIS G   -18                                                      
REMARK 465     HIS G   -17                                                      
REMARK 465     HIS G   -16                                                      
REMARK 465     HIS G   -15                                                      
REMARK 465     HIS G   -14                                                      
REMARK 465     LEU G   -13                                                      
REMARK 465     GLU G   -12                                                      
REMARK 465     SER G   -11                                                      
REMARK 465     THR G   -10                                                      
REMARK 465     SER G    -9                                                      
REMARK 465     LEU G    -8                                                      
REMARK 465     TYR G    -7                                                      
REMARK 465     LYS G    -6                                                      
REMARK 465     LYS G    -5                                                      
REMARK 465     ALA G    -4                                                      
REMARK 465     GLY G    -3                                                      
REMARK 465     PHE G    -2                                                      
REMARK 465     ASN G   202                                                      
REMARK 465     MET H   -23                                                      
REMARK 465     SER H   -22                                                      
REMARK 465     TYR H   -21                                                      
REMARK 465     TYR H   -20                                                      
REMARK 465     HIS H   -19                                                      
REMARK 465     HIS H   -18                                                      
REMARK 465     HIS H   -17                                                      
REMARK 465     HIS H   -16                                                      
REMARK 465     HIS H   -15                                                      
REMARK 465     HIS H   -14                                                      
REMARK 465     LEU H   -13                                                      
REMARK 465     GLU H   -12                                                      
REMARK 465     SER H   -11                                                      
REMARK 465     THR H   -10                                                      
REMARK 465     SER H    -9                                                      
REMARK 465     LEU H    -8                                                      
REMARK 465     TYR H    -7                                                      
REMARK 465     LYS H    -6                                                      
REMARK 465     LYS H    -5                                                      
REMARK 465     ALA H    -4                                                      
REMARK 465     GLY H    -3                                                      
REMARK 465     PHE H    -2                                                      
REMARK 465     MET H    -1                                                      
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT                     
REMARK 500                                                                      
REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT.                            
REMARK 500                                                                      
REMARK 500  ATM1  RES C  SSEQI   ATM2  RES C  SSEQI           DISTANCE          
REMARK 500   NZ   LYS D    79     O    HOH D  2041              2.17            
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: TORSION ANGLES                                             
REMARK 500                                                                      
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:            
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)                    
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-           
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400            
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        PSI       PHI                                   
REMARK 500    ASN A 145     -119.69     51.20                                   
REMARK 500    TYR A 169      -13.19   -147.93                                   
REMARK 500    LYS A 174     -135.08     50.60                                   
REMARK 500    ASN B 145     -118.62     52.78                                   
REMARK 500    TYR B 169      -13.19   -146.90                                   
REMARK 500    LYS B 174     -133.57     51.03                                   
REMARK 500    ASN C 145     -119.87     51.04                                   
REMARK 500    TYR C 169      -12.70   -149.07                                   
REMARK 500    LYS C 174     -133.99     52.97                                   
REMARK 500    ASN D 145     -119.88     53.50                                   
REMARK 500    TYR D 169      -13.54   -145.82                                   
REMARK 500    LYS D 174     -134.90     49.49                                   
REMARK 500    ASN E 145     -121.67     54.33                                   
REMARK 500    TYR E 169      -12.78   -147.58                                   
REMARK 500    LYS E 174     -133.31     51.94                                   
REMARK 500    ASN F 145     -117.95     53.14                                   
REMARK 500    TYR F 169      -13.29   -141.69                                   
REMARK 500    LYS F 174     -132.92     48.70                                   
REMARK 500    ASN G 145     -120.97     54.68                                   
REMARK 500    TYR G 169      -12.64   -143.11                                   
REMARK 500    LYS G 174     -135.30     51.03                                   
REMARK 500    ASN H 145     -118.68     52.74                                   
REMARK 500    TYR H 169      -14.02   -145.55                                   
REMARK 500    LYS H 174     -131.92     51.17                                   
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 620                                                                      
REMARK 620 METAL COORDINATION                                                   
REMARK 620 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 620 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE):                             
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MN A 302  MN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 HIS A  26   NE2                                                    
REMARK 620 2 HIS A  74   NE2  89.8                                              
REMARK 620 3 ASP A 163   OD2  77.9 111.5                                        
REMARK 620 4 HIS A 167   NE2  97.9 133.3 115.1                                  
REMARK 620 5 HOH A 303   O   168.7  96.4  91.0  84.7                            
REMARK 620 N                    1     2     3     4                             
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MN B 302  MN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 HIS B  26   NE2                                                    
REMARK 620 2 HIS B  74   NE2  88.6                                              
REMARK 620 3 ASP B 163   OD2  89.9 117.0                                        
REMARK 620 4 HIS B 167   NE2  92.2 129.4 113.6                                  
REMARK 620 5 HOH B 303   O   173.7  95.2  83.9  89.3                            
REMARK 620 N                    1     2     3     4                             
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MN C 302  MN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 HIS C  74   NE2                                                    
REMARK 620 2 HIS C  26   NE2  92.3                                              
REMARK 620 3 HIS C 167   NE2 131.2  92.1                                        
REMARK 620 4 ASP C 163   OD2 115.6  88.0 113.2                                  
REMARK 620 5 HOH C 303   O    86.4 171.6  95.0  85.1                            
REMARK 620 N                    1     2     3     4                             
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MN D 302  MN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 HIS D  74   NE2                                                    
REMARK 620 2 HIS D 167   NE2 133.0                                              
REMARK 620 3 HIS D  26   NE2  90.5  95.5                                        
REMARK 620 4 ASP D 163   OD2 108.9 118.1  82.2                                  
REMARK 620 5 HOH D 303   O    93.8  85.8 172.8  90.9                            
REMARK 620 N                    1     2     3     4                             
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MN E 302  MN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 HIS E 167   NE2                                                    
REMARK 620 2 HIS E  26   NE2  91.4                                              
REMARK 620 3 ASP E 163   OD2 114.3  87.8                                        
REMARK 620 4 HOH E 303   O    89.8 173.4  85.8                                  
REMARK 620 5 HIS E  74   NE2 134.2  95.8 111.1  88.0                            
REMARK 620 N                    1     2     3     4                             
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MN F 302  MN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 HIS F  74   NE2                                                    
REMARK 620 2 ASP F 163   OD2 115.1                                              
REMARK 620 3 HIS F 167   NE2 129.1 115.8                                        
REMARK 620 4 HOH F 303   O    96.3  84.4  87.8                                  
REMARK 620 5 HIS F  26   NE2  94.2  85.7  90.3 167.9                            
REMARK 620 N                    1     2     3     4                             
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MN G 302  MN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 HIS G  74   NE2                                                    
REMARK 620 2 ASP G 163   OD2 113.7                                              
REMARK 620 3 HIS G 167   NE2 129.6 116.7                                        
REMARK 620 4 HOH G 303   O    93.1  87.3  89.9                                  
REMARK 620 5 HIS G  26   NE2  87.8  87.5  93.6 174.7                            
REMARK 620 N                    1     2     3     4                             
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MN H 302  MN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 HOH H 303   O                                                      
REMARK 620 2 HIS H  26   NE2 167.6                                              
REMARK 620 3 HIS H  74   NE2  98.4  89.3                                        
REMARK 620 4 ASP H 163   OD2  85.9  82.4 108.0                                  
REMARK 620 5 HIS H 167   NE2  90.4  90.9 135.4 116.2                            
REMARK 620 N                    1     2     3     4                             
REMARK 800                                                                      
REMARK 800 SITE                                                                 
REMARK 800 SITE_IDENTIFIER: AC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MN A 302                  
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MN B 302                  
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC3                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MN C 302                  
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC4                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MN D 302                  
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC5                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MN E 302                  
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC6                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MN F 302                  
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC7                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MN G 302                  
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC8                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MN H 302                  
DBREF  4C7U A    1   202  UNP    O81235   SODM1_ARATH     30    231             
DBREF  4C7U B    1   202  UNP    O81235   SODM1_ARATH     30    231             
DBREF  4C7U C    1   202  UNP    O81235   SODM1_ARATH     30    231             
DBREF  4C7U D    1   202  UNP    O81235   SODM1_ARATH     30    231             
DBREF  4C7U E    1   202  UNP    O81235   SODM1_ARATH     30    231             
DBREF  4C7U F    1   202  UNP    O81235   SODM1_ARATH     30    231             
DBREF  4C7U G    1   202  UNP    O81235   SODM1_ARATH     30    231             
DBREF  4C7U H    1   202  UNP    O81235   SODM1_ARATH     30    231             
SEQADV 4C7U MET A  -23  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER A  -22  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR A  -21  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR A  -20  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS A  -19  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS A  -18  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS A  -17  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS A  -16  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS A  -15  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS A  -14  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LEU A  -13  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U GLU A  -12  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER A  -11  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U THR A  -10  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER A   -9  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LEU A   -8  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR A   -7  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LYS A   -6  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LYS A   -5  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U ALA A   -4  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U GLY A   -3  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U PHE A   -2  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U MET A   -1  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U MET B  -23  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER B  -22  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR B  -21  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR B  -20  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS B  -19  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS B  -18  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS B  -17  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS B  -16  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS B  -15  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS B  -14  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LEU B  -13  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U GLU B  -12  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER B  -11  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U THR B  -10  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER B   -9  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LEU B   -8  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR B   -7  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LYS B   -6  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LYS B   -5  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U ALA B   -4  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U GLY B   -3  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U PHE B   -2  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U MET B   -1  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U MET C  -23  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER C  -22  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR C  -21  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR C  -20  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS C  -19  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS C  -18  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS C  -17  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS C  -16  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS C  -15  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS C  -14  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LEU C  -13  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U GLU C  -12  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER C  -11  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U THR C  -10  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER C   -9  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LEU C   -8  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR C   -7  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LYS C   -6  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LYS C   -5  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U ALA C   -4  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U GLY C   -3  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U PHE C   -2  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U MET C   -1  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U MET D  -23  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER D  -22  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR D  -21  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR D  -20  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS D  -19  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS D  -18  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS D  -17  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS D  -16  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS D  -15  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS D  -14  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LEU D  -13  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U GLU D  -12  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER D  -11  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U THR D  -10  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER D   -9  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LEU D   -8  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR D   -7  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LYS D   -6  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LYS D   -5  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U ALA D   -4  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U GLY D   -3  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U PHE D   -2  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U MET D   -1  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U MET E  -23  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER E  -22  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR E  -21  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR E  -20  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS E  -19  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS E  -18  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS E  -17  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS E  -16  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS E  -15  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS E  -14  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LEU E  -13  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U GLU E  -12  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER E  -11  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U THR E  -10  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER E   -9  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LEU E   -8  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR E   -7  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LYS E   -6  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LYS E   -5  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U ALA E   -4  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U GLY E   -3  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U PHE E   -2  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U MET E   -1  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U MET F  -23  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER F  -22  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR F  -21  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR F  -20  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS F  -19  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS F  -18  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS F  -17  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS F  -16  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS F  -15  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS F  -14  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LEU F  -13  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U GLU F  -12  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER F  -11  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U THR F  -10  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER F   -9  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LEU F   -8  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR F   -7  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LYS F   -6  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LYS F   -5  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U ALA F   -4  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U GLY F   -3  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U PHE F   -2  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U MET F   -1  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U MET G  -23  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER G  -22  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR G  -21  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR G  -20  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS G  -19  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS G  -18  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS G  -17  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS G  -16  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS G  -15  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS G  -14  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LEU G  -13  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U GLU G  -12  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER G  -11  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U THR G  -10  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER G   -9  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LEU G   -8  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR G   -7  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LYS G   -6  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LYS G   -5  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U ALA G   -4  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U GLY G   -3  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U PHE G   -2  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U MET G   -1  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U MET H  -23  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER H  -22  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR H  -21  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR H  -20  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS H  -19  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS H  -18  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS H  -17  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS H  -16  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS H  -15  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U HIS H  -14  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LEU H  -13  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U GLU H  -12  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER H  -11  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U THR H  -10  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U SER H   -9  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LEU H   -8  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U TYR H   -7  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LYS H   -6  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U LYS H   -5  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U ALA H   -4  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U GLY H   -3  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U PHE H   -2  UNP  O81235              EXPRESSION TAG                 
SEQADV 4C7U MET H   -1  UNP  O81235              EXPRESSION TAG                 
SEQRES   1 A  225  MET SER TYR TYR HIS HIS HIS HIS HIS HIS LEU GLU SER          
SEQRES   2 A  225  THR SER LEU TYR LYS LYS ALA GLY PHE MET THR PHE THR          
SEQRES   3 A  225  LEU PRO ASP LEU PRO TYR ASP TYR GLY ALA LEU GLU PRO          
SEQRES   4 A  225  ALA ILE SER GLY GLU ILE MET GLN ILE HIS HIS GLN LYS          
SEQRES   5 A  225  HIS HIS GLN ALA TYR VAL THR ASN TYR ASN ASN ALA LEU          
SEQRES   6 A  225  GLU GLN LEU ASP GLN ALA VAL ASN LYS GLY ASP ALA SER          
SEQRES   7 A  225  THR VAL VAL LYS LEU GLN SER ALA ILE LYS PHE ASN GLY          
SEQRES   8 A  225  GLY GLY HIS VAL ASN HIS SER ILE PHE TRP LYS ASN LEU          
SEQRES   9 A  225  ALA PRO SER SER GLU GLY GLY GLY GLU PRO PRO LYS GLY          
SEQRES  10 A  225  SER LEU GLY SER ALA ILE ASP ALA HIS PHE GLY SER LEU          
SEQRES  11 A  225  GLU GLY LEU VAL LYS LYS MET SER ALA GLU GLY ALA ALA          
SEQRES  12 A  225  VAL GLN GLY SER GLY TRP VAL TRP LEU GLY LEU ASP LYS          
SEQRES  13 A  225  GLU LEU LYS LYS LEU VAL VAL ASP THR THR ALA ASN GLN          
SEQRES  14 A  225  ASP PRO LEU VAL THR LYS GLY GLY SER LEU VAL PRO LEU          
SEQRES  15 A  225  VAL GLY ILE ASP VAL TRP GLU HIS ALA TYR TYR LEU GLN          
SEQRES  16 A  225  TYR LYS ASN VAL ARG PRO GLU TYR LEU LYS ASN VAL TRP          
SEQRES  17 A  225  LYS VAL ILE ASN TRP LYS TYR ALA SER GLU VAL TYR GLU          
SEQRES  18 A  225  LYS GLU ASN ASN                                              
SEQRES   1 B  225  MET SER TYR TYR HIS HIS HIS HIS HIS HIS LEU GLU SER          
SEQRES   2 B  225  THR SER LEU TYR LYS LYS ALA GLY PHE MET THR PHE THR          
SEQRES   3 B  225  LEU PRO ASP LEU PRO TYR ASP TYR GLY ALA LEU GLU PRO          
SEQRES   4 B  225  ALA ILE SER GLY GLU ILE MET GLN ILE HIS HIS GLN LYS          
SEQRES   5 B  225  HIS HIS GLN ALA TYR VAL THR ASN TYR ASN ASN ALA LEU          
SEQRES   6 B  225  GLU GLN LEU ASP GLN ALA VAL ASN LYS GLY ASP ALA SER          
SEQRES   7 B  225  THR VAL VAL LYS LEU GLN SER ALA ILE LYS PHE ASN GLY          
SEQRES   8 B  225  GLY GLY HIS VAL ASN HIS SER ILE PHE TRP LYS ASN LEU          
SEQRES   9 B  225  ALA PRO SER SER GLU GLY GLY GLY GLU PRO PRO LYS GLY          
SEQRES  10 B  225  SER LEU GLY SER ALA ILE ASP ALA HIS PHE GLY SER LEU          
SEQRES  11 B  225  GLU GLY LEU VAL LYS LYS MET SER ALA GLU GLY ALA ALA          
SEQRES  12 B  225  VAL GLN GLY SER GLY TRP VAL TRP LEU GLY LEU ASP LYS          
SEQRES  13 B  225  GLU LEU LYS LYS LEU VAL VAL ASP THR THR ALA ASN GLN          
SEQRES  14 B  225  ASP PRO LEU VAL THR LYS GLY GLY SER LEU VAL PRO LEU          
SEQRES  15 B  225  VAL GLY ILE ASP VAL TRP GLU HIS ALA TYR TYR LEU GLN          
SEQRES  16 B  225  TYR LYS ASN VAL ARG PRO GLU TYR LEU LYS ASN VAL TRP          
SEQRES  17 B  225  LYS VAL ILE ASN TRP LYS TYR ALA SER GLU VAL TYR GLU          
SEQRES  18 B  225  LYS GLU ASN ASN                                              
SEQRES   1 C  225  MET SER TYR TYR HIS HIS HIS HIS HIS HIS LEU GLU SER          
SEQRES   2 C  225  THR SER LEU TYR LYS LYS ALA GLY PHE MET THR PHE THR          
SEQRES   3 C  225  LEU PRO ASP LEU PRO TYR ASP TYR GLY ALA LEU GLU PRO          
SEQRES   4 C  225  ALA ILE SER GLY GLU ILE MET GLN ILE HIS HIS GLN LYS          
SEQRES   5 C  225  HIS HIS GLN ALA TYR VAL THR ASN TYR ASN ASN ALA LEU          
SEQRES   6 C  225  GLU GLN LEU ASP GLN ALA VAL ASN LYS GLY ASP ALA SER          
SEQRES   7 C  225  THR VAL VAL LYS LEU GLN SER ALA ILE LYS PHE ASN GLY          
SEQRES   8 C  225  GLY GLY HIS VAL ASN HIS SER ILE PHE TRP LYS ASN LEU          
SEQRES   9 C  225  ALA PRO SER SER GLU GLY GLY GLY GLU PRO PRO LYS GLY          
SEQRES  10 C  225  SER LEU GLY SER ALA ILE ASP ALA HIS PHE GLY SER LEU          
SEQRES  11 C  225  GLU GLY LEU VAL LYS LYS MET SER ALA GLU GLY ALA ALA          
SEQRES  12 C  225  VAL GLN GLY SER GLY TRP VAL TRP LEU GLY LEU ASP LYS          
SEQRES  13 C  225  GLU LEU LYS LYS LEU VAL VAL ASP THR THR ALA ASN GLN          
SEQRES  14 C  225  ASP PRO LEU VAL THR LYS GLY GLY SER LEU VAL PRO LEU          
SEQRES  15 C  225  VAL GLY ILE ASP VAL TRP GLU HIS ALA TYR TYR LEU GLN          
SEQRES  16 C  225  TYR LYS ASN VAL ARG PRO GLU TYR LEU LYS ASN VAL TRP          
SEQRES  17 C  225  LYS VAL ILE ASN TRP LYS TYR ALA SER GLU VAL TYR GLU          
SEQRES  18 C  225  LYS GLU ASN ASN                                              
SEQRES   1 D  225  MET SER TYR TYR HIS HIS HIS HIS HIS HIS LEU GLU SER          
SEQRES   2 D  225  THR SER LEU TYR LYS LYS ALA GLY PHE MET THR PHE THR          
SEQRES   3 D  225  LEU PRO ASP LEU PRO TYR ASP TYR GLY ALA LEU GLU PRO          
SEQRES   4 D  225  ALA ILE SER GLY GLU ILE MET GLN ILE HIS HIS GLN LYS          
SEQRES   5 D  225  HIS HIS GLN ALA TYR VAL THR ASN TYR ASN ASN ALA LEU          
SEQRES   6 D  225  GLU GLN LEU ASP GLN ALA VAL ASN LYS GLY ASP ALA SER          
SEQRES   7 D  225  THR VAL VAL LYS LEU GLN SER ALA ILE LYS PHE ASN GLY          
SEQRES   8 D  225  GLY GLY HIS VAL ASN HIS SER ILE PHE TRP LYS ASN LEU          
SEQRES   9 D  225  ALA PRO SER SER GLU GLY GLY GLY GLU PRO PRO LYS GLY          
SEQRES  10 D  225  SER LEU GLY SER ALA ILE ASP ALA HIS PHE GLY SER LEU          
SEQRES  11 D  225  GLU GLY LEU VAL LYS LYS MET SER ALA GLU GLY ALA ALA          
SEQRES  12 D  225  VAL GLN GLY SER GLY TRP VAL TRP LEU GLY LEU ASP LYS          
SEQRES  13 D  225  GLU LEU LYS LYS LEU VAL VAL ASP THR THR ALA ASN GLN          
SEQRES  14 D  225  ASP PRO LEU VAL THR LYS GLY GLY SER LEU VAL PRO LEU          
SEQRES  15 D  225  VAL GLY ILE ASP VAL TRP GLU HIS ALA TYR TYR LEU GLN          
SEQRES  16 D  225  TYR LYS ASN VAL ARG PRO GLU TYR LEU LYS ASN VAL TRP          
SEQRES  17 D  225  LYS VAL ILE ASN TRP LYS TYR ALA SER GLU VAL TYR GLU          
SEQRES  18 D  225  LYS GLU ASN ASN                                              
SEQRES   1 E  225  MET SER TYR TYR HIS HIS HIS HIS HIS HIS LEU GLU SER          
SEQRES   2 E  225  THR SER LEU TYR LYS LYS ALA GLY PHE MET THR PHE THR          
SEQRES   3 E  225  LEU PRO ASP LEU PRO TYR ASP TYR GLY ALA LEU GLU PRO          
SEQRES   4 E  225  ALA ILE SER GLY GLU ILE MET GLN ILE HIS HIS GLN LYS          
SEQRES   5 E  225  HIS HIS GLN ALA TYR VAL THR ASN TYR ASN ASN ALA LEU          
SEQRES   6 E  225  GLU GLN LEU ASP GLN ALA VAL ASN LYS GLY ASP ALA SER          
SEQRES   7 E  225  THR VAL VAL LYS LEU GLN SER ALA ILE LYS PHE ASN GLY          
SEQRES   8 E  225  GLY GLY HIS VAL ASN HIS SER ILE PHE TRP LYS ASN LEU          
SEQRES   9 E  225  ALA PRO SER SER GLU GLY GLY GLY GLU PRO PRO LYS GLY          
SEQRES  10 E  225  SER LEU GLY SER ALA ILE ASP ALA HIS PHE GLY SER LEU          
SEQRES  11 E  225  GLU GLY LEU VAL LYS LYS MET SER ALA GLU GLY ALA ALA          
SEQRES  12 E  225  VAL GLN GLY SER GLY TRP VAL TRP LEU GLY LEU ASP LYS          
SEQRES  13 E  225  GLU LEU LYS LYS LEU VAL VAL ASP THR THR ALA ASN GLN          
SEQRES  14 E  225  ASP PRO LEU VAL THR LYS GLY GLY SER LEU VAL PRO LEU          
SEQRES  15 E  225  VAL GLY ILE ASP VAL TRP GLU HIS ALA TYR TYR LEU GLN          
SEQRES  16 E  225  TYR LYS ASN VAL ARG PRO GLU TYR LEU LYS ASN VAL TRP          
SEQRES  17 E  225  LYS VAL ILE ASN TRP LYS TYR ALA SER GLU VAL TYR GLU          
SEQRES  18 E  225  LYS GLU ASN ASN                                              
SEQRES   1 F  225  MET SER TYR TYR HIS HIS HIS HIS HIS HIS LEU GLU SER          
SEQRES   2 F  225  THR SER LEU TYR LYS LYS ALA GLY PHE MET THR PHE THR          
SEQRES   3 F  225  LEU PRO ASP LEU PRO TYR ASP TYR GLY ALA LEU GLU PRO          
SEQRES   4 F  225  ALA ILE SER GLY GLU ILE MET GLN ILE HIS HIS GLN LYS          
SEQRES   5 F  225  HIS HIS GLN ALA TYR VAL THR ASN TYR ASN ASN ALA LEU          
SEQRES   6 F  225  GLU GLN LEU ASP GLN ALA VAL ASN LYS GLY ASP ALA SER          
SEQRES   7 F  225  THR VAL VAL LYS LEU GLN SER ALA ILE LYS PHE ASN GLY          
SEQRES   8 F  225  GLY GLY HIS VAL ASN HIS SER ILE PHE TRP LYS ASN LEU          
SEQRES   9 F  225  ALA PRO SER SER GLU GLY GLY GLY GLU PRO PRO LYS GLY          
SEQRES  10 F  225  SER LEU GLY SER ALA ILE ASP ALA HIS PHE GLY SER LEU          
SEQRES  11 F  225  GLU GLY LEU VAL LYS LYS MET SER ALA GLU GLY ALA ALA          
SEQRES  12 F  225  VAL GLN GLY SER GLY TRP VAL TRP LEU GLY LEU ASP LYS          
SEQRES  13 F  225  GLU LEU LYS LYS LEU VAL VAL ASP THR THR ALA ASN GLN          
SEQRES  14 F  225  ASP PRO LEU VAL THR LYS GLY GLY SER LEU VAL PRO LEU          
SEQRES  15 F  225  VAL GLY ILE ASP VAL TRP GLU HIS ALA TYR TYR LEU GLN          
SEQRES  16 F  225  TYR LYS ASN VAL ARG PRO GLU TYR LEU LYS ASN VAL TRP          
SEQRES  17 F  225  LYS VAL ILE ASN TRP LYS TYR ALA SER GLU VAL TYR GLU          
SEQRES  18 F  225  LYS GLU ASN ASN                                              
SEQRES   1 G  225  MET SER TYR TYR HIS HIS HIS HIS HIS HIS LEU GLU SER          
SEQRES   2 G  225  THR SER LEU TYR LYS LYS ALA GLY PHE MET THR PHE THR          
SEQRES   3 G  225  LEU PRO ASP LEU PRO TYR ASP TYR GLY ALA LEU GLU PRO          
SEQRES   4 G  225  ALA ILE SER GLY GLU ILE MET GLN ILE HIS HIS GLN LYS          
SEQRES   5 G  225  HIS HIS GLN ALA TYR VAL THR ASN TYR ASN ASN ALA LEU          
SEQRES   6 G  225  GLU GLN LEU ASP GLN ALA VAL ASN LYS GLY ASP ALA SER          
SEQRES   7 G  225  THR VAL VAL LYS LEU GLN SER ALA ILE LYS PHE ASN GLY          
SEQRES   8 G  225  GLY GLY HIS VAL ASN HIS SER ILE PHE TRP LYS ASN LEU          
SEQRES   9 G  225  ALA PRO SER SER GLU GLY GLY GLY GLU PRO PRO LYS GLY          
SEQRES  10 G  225  SER LEU GLY SER ALA ILE ASP ALA HIS PHE GLY SER LEU          
SEQRES  11 G  225  GLU GLY LEU VAL LYS LYS MET SER ALA GLU GLY ALA ALA          
SEQRES  12 G  225  VAL GLN GLY SER GLY TRP VAL TRP LEU GLY LEU ASP LYS          
SEQRES  13 G  225  GLU LEU LYS LYS LEU VAL VAL ASP THR THR ALA ASN GLN          
SEQRES  14 G  225  ASP PRO LEU VAL THR LYS GLY GLY SER LEU VAL PRO LEU          
SEQRES  15 G  225  VAL GLY ILE ASP VAL TRP GLU HIS ALA TYR TYR LEU GLN          
SEQRES  16 G  225  TYR LYS ASN VAL ARG PRO GLU TYR LEU LYS ASN VAL TRP          
SEQRES  17 G  225  LYS VAL ILE ASN TRP LYS TYR ALA SER GLU VAL TYR GLU          
SEQRES  18 G  225  LYS GLU ASN ASN                                              
SEQRES   1 H  225  MET SER TYR TYR HIS HIS HIS HIS HIS HIS LEU GLU SER          
SEQRES   2 H  225  THR SER LEU TYR LYS LYS ALA GLY PHE MET THR PHE THR          
SEQRES   3 H  225  LEU PRO ASP LEU PRO TYR ASP TYR GLY ALA LEU GLU PRO          
SEQRES   4 H  225  ALA ILE SER GLY GLU ILE MET GLN ILE HIS HIS GLN LYS          
SEQRES   5 H  225  HIS HIS GLN ALA TYR VAL THR ASN TYR ASN ASN ALA LEU          
SEQRES   6 H  225  GLU GLN LEU ASP GLN ALA VAL ASN LYS GLY ASP ALA SER          
SEQRES   7 H  225  THR VAL VAL LYS LEU GLN SER ALA ILE LYS PHE ASN GLY          
SEQRES   8 H  225  GLY GLY HIS VAL ASN HIS SER ILE PHE TRP LYS ASN LEU          
SEQRES   9 H  225  ALA PRO SER SER GLU GLY GLY GLY GLU PRO PRO LYS GLY          
SEQRES  10 H  225  SER LEU GLY SER ALA ILE ASP ALA HIS PHE GLY SER LEU          
SEQRES  11 H  225  GLU GLY LEU VAL LYS LYS MET SER ALA GLU GLY ALA ALA          
SEQRES  12 H  225  VAL GLN GLY SER GLY TRP VAL TRP LEU GLY LEU ASP LYS          
SEQRES  13 H  225  GLU LEU LYS LYS LEU VAL VAL ASP THR THR ALA ASN GLN          
SEQRES  14 H  225  ASP PRO LEU VAL THR LYS GLY GLY SER LEU VAL PRO LEU          
SEQRES  15 H  225  VAL GLY ILE ASP VAL TRP GLU HIS ALA TYR TYR LEU GLN          
SEQRES  16 H  225  TYR LYS ASN VAL ARG PRO GLU TYR LEU LYS ASN VAL TRP          
SEQRES  17 H  225  LYS VAL ILE ASN TRP LYS TYR ALA SER GLU VAL TYR GLU          
SEQRES  18 H  225  LYS GLU ASN ASN                                              
HET     MN  A 302       1                                                       
HET     MN  B 302       1                                                       
HET     MN  C 302       1                                                       
HET     MN  D 302       1                                                       
HET     MN  E 302       1                                                       
HET     MN  F 302       1                                                       
HET     MN  G 302       1                                                       
HET     MN  H 302       1                                                       
HETNAM      MN MANGANESE (II) ION                                               
FORMUL   9   MN    8(MN 2+)                                                     
FORMUL  17  HOH   *616(H2 O)                                                    
HELIX    1   1 ASP A   10  GLU A   15  5                                   6    
HELIX    2   2 SER A   19  LYS A   29  1                                  11    
HELIX    3   3 LYS A   29  GLY A   52  1                                  24    
HELIX    4   4 ASP A   53  LEU A   60  1                                   8    
HELIX    5   5 LEU A   60  ASN A   80  1                                  21    
HELIX    6   6 PRO A   83  GLY A   87  5                                   5    
HELIX    7   7 LYS A   93  GLY A  105  1                                  13    
HELIX    8   8 SER A  106  VAL A  121  1                                  16    
HELIX    9   9 PRO A  148  GLY A  153  5                                   6    
HELIX   10  10 TRP A  165  ALA A  168  5                                   4    
HELIX   11  11 TYR A  169  LYS A  174  1                                   6    
HELIX   12  12 VAL A  176  VAL A  184  1                                   9    
HELIX   13  13 TRP A  185  VAL A  187  5                                   3    
HELIX   14  14 ASN A  189  GLU A  200  1                                  12    
HELIX   15  15 SER B   19  LYS B   29  1                                  11    
HELIX   16  16 LYS B   29  LYS B   51  1                                  23    
HELIX   17  17 ASP B   53  LEU B   60  1                                   8    
HELIX   18  18 LEU B   60  ASN B   80  1                                  21    
HELIX   19  19 PRO B   83  GLY B   87  5                                   5    
HELIX   20  20 LYS B   93  GLY B  105  1                                  13    
HELIX   21  21 SER B  106  ALA B  120  1                                  15    
HELIX   22  22 PRO B  148  GLY B  153  5                                   6    
HELIX   23  23 TRP B  165  ALA B  168  5                                   4    
HELIX   24  24 TYR B  169  LYS B  174  1                                   6    
HELIX   25  25 VAL B  176  TRP B  185  1                                  10    
HELIX   26  26 ASN B  189  GLU B  200  1                                  12    
HELIX   27  27 SER C   19  LYS C   29  1                                  11    
HELIX   28  28 LYS C   29  LYS C   51  1                                  23    
HELIX   29  29 ASP C   53  LEU C   60  1                                   8    
HELIX   30  30 LEU C   60  ASN C   80  1                                  21    
HELIX   31  31 PRO C   83  GLY C   87  5                                   5    
HELIX   32  32 LYS C   93  GLY C  105  1                                  13    
HELIX   33  33 SER C  106  ALA C  120  1                                  15    
HELIX   34  34 PRO C  148  GLY C  153  5                                   6    
HELIX   35  35 TRP C  165  ALA C  168  5                                   4    
HELIX   36  36 TYR C  169  LYS C  174  1                                   6    
HELIX   37  37 VAL C  176  VAL C  184  1                                   9    
HELIX   38  38 TRP C  185  VAL C  187  5                                   3    
HELIX   39  39 ASN C  189  GLU C  200  1                                  12    
HELIX   40  40 SER D   19  LYS D   29  1                                  11    
HELIX   41  41 LYS D   29  GLY D   52  1                                  24    
HELIX   42  42 ASP D   53  LEU D   60  1                                   8    
HELIX   43  43 LEU D   60  ASN D   80  1                                  21    
HELIX   44  44 PRO D   83  GLY D   87  5                                   5    
HELIX   45  45 LYS D   93  GLY D  105  1                                  13    
HELIX   46  46 SER D  106  VAL D  121  1                                  16    
HELIX   47  47 PRO D  148  GLY D  153  5                                   6    
HELIX   48  48 TRP D  165  ALA D  168  5                                   4    
HELIX   49  49 TYR D  169  LYS D  174  1                                   6    
HELIX   50  50 VAL D  176  VAL D  184  1                                   9    
HELIX   51  51 TRP D  185  VAL D  187  5                                   3    
HELIX   52  52 ASN D  189  GLU D  200  1                                  12    
HELIX   53  53 SER E   19  LYS E   29  1                                  11    
HELIX   54  54 LYS E   29  GLY E   52  1                                  24    
HELIX   55  55 ASP E   53  LEU E   60  1                                   8    
HELIX   56  56 LEU E   60  ASN E   80  1                                  21    
HELIX   57  57 PRO E   83  GLY E   87  5                                   5    
HELIX   58  58 LYS E   93  GLY E  105  1                                  13    
HELIX   59  59 SER E  106  ALA E  120  1                                  15    
HELIX   60  60 PRO E  148  GLY E  153  5                                   6    
HELIX   61  61 TRP E  165  ALA E  168  5                                   4    
HELIX   62  62 TYR E  169  LYS E  174  1                                   6    
HELIX   63  63 VAL E  176  VAL E  184  1                                   9    
HELIX   64  64 TRP E  185  VAL E  187  5                                   3    
HELIX   65  65 ASN E  189  GLU E  200  1                                  12    
HELIX   66  66 SER F   19  LYS F   29  1                                  11    
HELIX   67  67 LYS F   29  GLY F   52  1                                  24    
HELIX   68  68 ASP F   53  LEU F   60  1                                   8    
HELIX   69  69 LEU F   60  ASN F   80  1                                  21    
HELIX   70  70 PRO F   83  GLY F   87  5                                   5    
HELIX   71  71 LYS F   93  GLY F  105  1                                  13    
HELIX   72  72 SER F  106  ALA F  120  1                                  15    
HELIX   73  73 PRO F  148  GLY F  153  5                                   6    
HELIX   74  74 TRP F  165  ALA F  168  5                                   4    
HELIX   75  75 TYR F  169  LYS F  174  1                                   6    
HELIX   76  76 VAL F  176  VAL F  184  1                                   9    
HELIX   77  77 TRP F  185  VAL F  187  5                                   3    
HELIX   78  78 ASN F  189  GLU F  200  1                                  12    
HELIX   79  79 ASP G   10  GLU G   15  5                                   6    
HELIX   80  80 SER G   19  LYS G   29  1                                  11    
HELIX   81  81 LYS G   29  GLY G   52  1                                  24    
HELIX   82  82 ASP G   53  LEU G   60  1                                   8    
HELIX   83  83 LEU G   60  ASN G   80  1                                  21    
HELIX   84  84 PRO G   83  GLY G   87  5                                   5    
HELIX   85  85 LYS G   93  GLY G  105  1                                  13    
HELIX   86  86 SER G  106  VAL G  121  1                                  16    
HELIX   87  87 PRO G  148  GLY G  153  5                                   6    
HELIX   88  88 TRP G  165  ALA G  168  5                                   4    
HELIX   89  89 TYR G  169  LYS G  174  1                                   6    
HELIX   90  90 VAL G  176  VAL G  184  1                                   9    
HELIX   91  91 TRP G  185  VAL G  187  5                                   3    
HELIX   92  92 ASN G  189  GLU G  200  1                                  12    
HELIX   93  93 SER H   19  LYS H   29  1                                  11    
HELIX   94  94 LYS H   29  GLY H   52  1                                  24    
HELIX   95  95 ASP H   53  LEU H   60  1                                   8    
HELIX   96  96 LEU H   60  ASN H   80  1                                  21    
HELIX   97  97 PRO H   83  GLY H   87  5                                   5    
HELIX   98  98 LYS H   93  GLY H  105  1                                  13    
HELIX   99  99 SER H  106  VAL H  121  1                                  16    
HELIX  100 100 PRO H  148  GLY H  153  5                                   6    
HELIX  101 101 TRP H  165  ALA H  168  5                                   4    
HELIX  102 102 TYR H  169  LYS H  174  1                                   6    
HELIX  103 103 VAL H  176  VAL H  184  1                                   9    
HELIX  104 104 TRP H  185  VAL H  187  5                                   3    
HELIX  105 105 ASN H  189  GLU H  200  1                                  12    
SHEET    1  AA 3 LYS A 137  ALA A 144  0                                        
SHEET    2  AA 3 GLY A 125  ASP A 132 -1  O  TRP A 126   N  THR A 143           
SHEET    3  AA 3 LEU A 156  ASP A 163 -1  O  VAL A 157   N  LEU A 131           
SHEET    1  BA 3 LYS B 137  ALA B 144  0                                        
SHEET    2  BA 3 GLY B 125  ASP B 132 -1  O  TRP B 126   N  THR B 143           
SHEET    3  BA 3 LEU B 156  ASP B 163 -1  O  VAL B 157   N  LEU B 131           
SHEET    1  CA 3 LYS C 137  ALA C 144  0                                        
SHEET    2  CA 3 GLY C 125  ASP C 132 -1  O  TRP C 126   N  THR C 143           
SHEET    3  CA 3 LEU C 156  ASP C 163 -1  O  VAL C 157   N  LEU C 131           
SHEET    1  DA 3 LYS D 137  ALA D 144  0                                        
SHEET    2  DA 3 GLY D 125  ASP D 132 -1  O  TRP D 126   N  THR D 143           
SHEET    3  DA 3 LEU D 156  ASP D 163 -1  O  VAL D 157   N  LEU D 131           
SHEET    1  EA 3 LYS E 137  ALA E 144  0                                        
SHEET    2  EA 3 GLY E 125  ASP E 132 -1  O  TRP E 126   N  THR E 143           
SHEET    3  EA 3 LEU E 156  ASP E 163 -1  O  VAL E 157   N  LEU E 131           
SHEET    1  FA 3 LYS F 137  ALA F 144  0                                        
SHEET    2  FA 3 GLY F 125  ASP F 132 -1  O  TRP F 126   N  THR F 143           
SHEET    3  FA 3 LEU F 156  ASP F 163 -1  O  VAL F 157   N  LEU F 131           
SHEET    1  GA 3 LYS G 137  ALA G 144  0                                        
SHEET    2  GA 3 GLY G 125  ASP G 132 -1  O  TRP G 126   N  THR G 143           
SHEET    3  GA 3 LEU G 156  ASP G 163 -1  O  VAL G 157   N  LEU G 131           
SHEET    1  HA 3 LYS H 137  ALA H 144  0                                        
SHEET    2  HA 3 GLY H 125  ASP H 132 -1  O  TRP H 126   N  THR H 143           
SHEET    3  HA 3 LEU H 156  ASP H 163 -1  O  VAL H 157   N  LEU H 131           
LINK        MN    MN A 302                 NE2 HIS A  26     1555   1555  2.25  
LINK        MN    MN A 302                 NE2 HIS A  74     1555   1555  2.18  
LINK        MN    MN A 302                 OD2 ASP A 163     1555   1555  1.94  
LINK        MN    MN A 302                 NE2 HIS A 167     1555   1555  2.20  
LINK        MN    MN A 302                 O   HOH A 303     1555   1555  2.32  
LINK        MN    MN B 302                 NE2 HIS B  26     1555   1555  2.23  
LINK        MN    MN B 302                 NE2 HIS B  74     1555   1555  2.24  
LINK        MN    MN B 302                 OD2 ASP B 163     1555   1555  1.99  
LINK        MN    MN B 302                 NE2 HIS B 167     1555   1555  2.35  
LINK        MN    MN B 302                 O   HOH B 303     1555   1555  2.24  
LINK        MN    MN C 302                 NE2 HIS C  74     1555   1555  2.08  
LINK        MN    MN C 302                 NE2 HIS C  26     1555   1555  2.16  
LINK        MN    MN C 302                 NE2 HIS C 167     1555   1555  2.34  
LINK        MN    MN C 302                 OD2 ASP C 163     1555   1555  1.97  
LINK        MN    MN C 302                 O   HOH C 303     1555   1555  2.19  
LINK        MN    MN D 302                 NE2 HIS D  74     1555   1555  2.17  
LINK        MN    MN D 302                 NE2 HIS D 167     1555   1555  2.16  
LINK        MN    MN D 302                 NE2 HIS D  26     1555   1555  2.30  
LINK        MN    MN D 302                 OD2 ASP D 163     1555   1555  1.97  
LINK        MN    MN D 302                 O   HOH D 303     1555   1555  2.16  
LINK        MN    MN E 302                 NE2 HIS E 167     1555   1555  2.25  
LINK        MN    MN E 302                 NE2 HIS E  26     1555   1555  2.23  
LINK        MN    MN E 302                 OD2 ASP E 163     1555   1555  1.94  
LINK        MN    MN E 302                 O   HOH E 303     1555   1555  2.30  
LINK        MN    MN E 302                 NE2 HIS E  74     1555   1555  2.08  
LINK        MN    MN F 302                 NE2 HIS F  74     1555   1555  2.10  
LINK        MN    MN F 302                 OD2 ASP F 163     1555   1555  1.91  
LINK        MN    MN F 302                 NE2 HIS F 167     1555   1555  2.27  
LINK        MN    MN F 302                 O   HOH F 303     1555   1555  2.25  
LINK        MN    MN F 302                 NE2 HIS F  26     1555   1555  2.20  
LINK        MN    MN G 302                 NE2 HIS G  74     1555   1555  2.10  
LINK        MN    MN G 302                 OD2 ASP G 163     1555   1555  1.98  
LINK        MN    MN G 302                 NE2 HIS G 167     1555   1555  2.31  
LINK        MN    MN G 302                 O   HOH G 303     1555   1555  2.38  
LINK        MN    MN G 302                 NE2 HIS G  26     1555   1555  2.24  
LINK        MN    MN H 302                 O   HOH H 303     1555   1555  2.32  
LINK        MN    MN H 302                 NE2 HIS H  26     1555   1555  2.32  
LINK        MN    MN H 302                 NE2 HIS H  74     1555   1555  2.06  
LINK        MN    MN H 302                 OD2 ASP H 163     1555   1555  1.85  
LINK        MN    MN H 302                 NE2 HIS H 167     1555   1555  2.20  
CISPEP   1 GLU A   15    PRO A   16          0         3.68                     
CISPEP   2 GLU B   15    PRO B   16          0         4.03                     
CISPEP   3 GLU C   15    PRO C   16          0         3.79                     
CISPEP   4 GLU D   15    PRO D   16          0         4.32                     
CISPEP   5 GLU E   15    PRO E   16          0         4.07                     
CISPEP   6 GLU F   15    PRO F   16          0         4.73                     
CISPEP   7 GLU G   15    PRO G   16          0         3.78                     
CISPEP   8 GLU H   15    PRO H   16          0         5.94                     
SITE     1 AC1  5 HIS A  26  HIS A  74  ASP A 163  HIS A 167                    
SITE     2 AC1  5 HOH A 303                                                     
SITE     1 AC2  5 HIS B  26  HIS B  74  ASP B 163  HIS B 167                    
SITE     2 AC2  5 HOH B 303                                                     
SITE     1 AC3  5 HIS C  26  HIS C  74  ASP C 163  HIS C 167                    
SITE     2 AC3  5 HOH C 303                                                     
SITE     1 AC4  5 HIS D  26  HIS D  74  ASP D 163  HIS D 167                    
SITE     2 AC4  5 HOH D 303                                                     
SITE     1 AC5  5 HIS E  26  HIS E  74  ASP E 163  HIS E 167                    
SITE     2 AC5  5 HOH E 303                                                     
SITE     1 AC6  5 HIS F  26  HIS F  74  ASP F 163  HIS F 167                    
SITE     2 AC6  5 HOH F 303                                                     
SITE     1 AC7  5 HIS G  26  HIS G  74  ASP G 163  HIS G 167                    
SITE     2 AC7  5 HOH G 303                                                     
SITE     1 AC8  5 HIS H  26  HIS H  74  ASP H 163  HIS H 167                    
SITE     2 AC8  5 HOH H 303                                                     
CRYST1   58.952   59.181  107.980  90.55  90.51  89.85 P 1           8          
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      0.016963 -0.000044  0.000151        0.00000                         
SCALE2      0.000000  0.016897  0.000162        0.00000                         
SCALE3      0.000000  0.000000  0.009262        0.00000                         
MTRIX1   1  0.999900  0.010200  0.012100       27.84290    1                    
MTRIX2   1  0.010800 -0.998500 -0.052900       80.05530    1                    
MTRIX3   1  0.011500  0.053000 -0.998500      210.47190    1                    
MTRIX1   2 -0.009900 -0.999900 -0.013300      100.76510    1                    
MTRIX2   2  0.998700 -0.010600  0.050300        2.60030    1                    
MTRIX3   2 -0.050400 -0.012800  0.998600       56.91620    1                    
MTRIX1   3  0.001100 -1.000000  0.000800      129.24880    1                    
MTRIX2   3 -1.000000 -0.001100 -0.000700       70.31640    1                    
MTRIX3   3  0.000700 -0.000800 -1.000000      158.38730    1                    
MTRIX1   4 -0.997500  0.019900  0.068300      140.39120    1                    
MTRIX2   4 -0.016200 -0.998400  0.054000       99.38570    1                    
MTRIX3   4  0.069200  0.052700  0.996200       -7.33620    1                    
MTRIX1   5 -0.997700 -0.006700 -0.068100      127.59170    1                    
MTRIX2   5 -0.007600  0.999900  0.012700      -31.02630    1                    
MTRIX3   5  0.068000  0.013200 -0.997600      207.96140    1                    
MTRIX1   6 -0.016200  0.997600 -0.067000       24.47030    1                    
MTRIX2   6  0.998600  0.012800 -0.050700      -23.15040    1                    
MTRIX3   6 -0.049700 -0.067800 -0.996500      165.84420    1                    
MTRIX1   7  0.008200  0.997400  0.071700       45.43120    1                    
MTRIX2   7 -0.999900  0.008800 -0.008900       99.43120    1                    
MTRIX3   7 -0.009500 -0.071600  0.997400       56.54800    1                    
(ATOM LINES ARE NOT SHOWN.)
END                                                                             
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