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Database: PDB
Entry: 5GAP
LinkDB: 5GAP
Original site: 5GAP 
HEADER    TRANSCRIPTION                           15-DEC-15   5GAP              
TITLE     BODY REGION OF THE U4/U6.U5 TRI-SNRNP                                 
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: U4 SNRNA, 5' REGION, NUCLEOTIDES 1-67;                     
COMPND   3 CHAIN: V;                                                            
COMPND   4 OTHER_DETAILS: U4 SNRNA 5' REGION, NUCLEOTIDES 1-67.;                
COMPND   5 MOL_ID: 2;                                                           
COMPND   6 MOLECULE: U6 SNRNA;                                                  
COMPND   7 CHAIN: W;                                                            
COMPND   8 MOL_ID: 3;                                                           
COMPND   9 MOLECULE: U5 SNRNA;                                                  
COMPND  10 CHAIN: U;                                                            
COMPND  11 MOL_ID: 4;                                                           
COMPND  12 MOLECULE: UNKNOWN PROTEIN;                                           
COMPND  13 CHAIN: x;                                                            
COMPND  14 OTHER_DETAILS: CLEAR HELICAL REGIONS WERE BUILT AS POLY(ALA) BUT     
COMPND  15 COULD NOT BE ASSIGNED TO A SPECIFIC PROTEIN.;                        
COMPND  16 MOL_ID: 5;                                                           
COMPND  17 MOLECULE: PRE-MRNA-SPLICING FACTOR 8;                                
COMPND  18 CHAIN: A;                                                            
COMPND  19 SYNONYM: PRP8;                                                       
COMPND  20 MOL_ID: 6;                                                           
COMPND  21 MOLECULE: U4/U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP4;                
COMPND  22 CHAIN: H;                                                            
COMPND  23 SYNONYM: PRE-MRNA-PROCESSING PROTEIN 4, PRP4;                        
COMPND  24 MOL_ID: 7;                                                           
COMPND  25 MOLECULE: PRE-MRNA-SPLICING FACTOR 6;                                
COMPND  26 CHAIN: J;                                                            
COMPND  27 SYNONYM: PRP6;                                                       
COMPND  28 MOL_ID: 8;                                                           
COMPND  29 MOLECULE: SPLICEOSOMAL PROTEIN DIB1;                                 
COMPND  30 CHAIN: D;                                                            
COMPND  31 SYNONYM: DIB1;                                                       
COMPND  32 MOL_ID: 9;                                                           
COMPND  33 MOLECULE: PRE-MRNA-PROCESSING FACTOR 31;                             
COMPND  34 CHAIN: F;                                                            
COMPND  35 SYNONYM: PRP31;                                                      
COMPND  36 MOL_ID: 10;                                                          
COMPND  37 MOLECULE: U4/U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP3;                
COMPND  38 CHAIN: G;                                                            
COMPND  39 SYNONYM: PRE-MRNA-SPLICING FACTOR 3, PRP3;                           
COMPND  40 MOL_ID: 11;                                                          
COMPND  41 MOLECULE: 13 KDA RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN;               
COMPND  42 CHAIN: K;                                                            
COMPND  43 SYNONYM: SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN 1, SNU13;
COMPND  44 MOL_ID: 12;                                                          
COMPND  45 MOLECULE: PRE-MRNA-SPLICING HELICASE BRR2;                           
COMPND  46 CHAIN: B;                                                            
COMPND  47 SYNONYM: PROTEIN SNU246;                                             
COMPND  48 EC: 3.6.4.13                                                         
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE   3 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE   4 ORGANISM_TAXID: 4932;                                                
SOURCE   5 MOL_ID: 2;                                                           
SOURCE   6 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE   7 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE   8 ORGANISM_TAXID: 4932;                                                
SOURCE   9 MOL_ID: 3;                                                           
SOURCE  10 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  11 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  12 ORGANISM_TAXID: 4932;                                                
SOURCE  13 MOL_ID: 4;                                                           
SOURCE  14 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  15 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  16 ORGANISM_TAXID: 4932;                                                
SOURCE  17 MOL_ID: 5;                                                           
SOURCE  18 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  19 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  20 ORGANISM_TAXID: 4932;                                                
SOURCE  21 MOL_ID: 6;                                                           
SOURCE  22 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  23 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  24 ORGANISM_TAXID: 4932;                                                
SOURCE  25 MOL_ID: 7;                                                           
SOURCE  26 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  27 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  28 ORGANISM_TAXID: 4932;                                                
SOURCE  29 MOL_ID: 8;                                                           
SOURCE  30 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  31 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  32 ORGANISM_TAXID: 4932;                                                
SOURCE  33 MOL_ID: 9;                                                           
SOURCE  34 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  35 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  36 ORGANISM_TAXID: 4932;                                                
SOURCE  37 MOL_ID: 10;                                                          
SOURCE  38 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  39 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  40 ORGANISM_TAXID: 4932;                                                
SOURCE  41 MOL_ID: 11;                                                          
SOURCE  42 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  43 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  44 ORGANISM_TAXID: 4932;                                                
SOURCE  45 MOL_ID: 12;                                                          
SOURCE  46 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  47 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  48 ORGANISM_TAXID: 4932                                                 
KEYWDS    TRANSCRIPTION, SNRNP, SPLICEOSOME, RNA-PROTEIN COMPLEX, U4/U6.U5      
KEYWDS   2 SNRNP                                                                
EXPDTA    ELECTRON MICROSCOPY                                                   
AUTHOR    T.H.D.NGUYEN,W.P.GALEJ,C.OUBRIDGE,X.C.BAI,A.NEWMAN,S.SCHERES,K.NAGAI  
REVDAT   4   30-AUG-17 5GAP    1       REMARK                                   
REVDAT   3   09-MAR-16 5GAP    1       JRNL                                     
REVDAT   2   02-MAR-16 5GAP    1       JRNL                                     
REVDAT   1   27-JAN-16 5GAP    0                                                
JRNL        AUTH   T.H.NGUYEN,W.P.GALEJ,X.C.BAI,C.OUBRIDGE,A.J.NEWMAN,          
JRNL        AUTH 2 S.H.SCHERES,K.NAGAI                                          
JRNL        TITL   CRYO-EM STRUCTURE OF THE YEAST U4/U6.U5 TRI-SNRNP AT 3.7     
JRNL        TITL 2 ANGSTROM RESOLUTION.                                         
JRNL        REF    NATURE                        V. 530   298 2016              
JRNL        REFN                   ESSN 1476-4687                               
JRNL        PMID   26829225                                                     
JRNL        DOI    10.1038/NATURE16940                                          
REMARK   2                                                                      
REMARK   2 RESOLUTION.    3.60 ANGSTROMS.                                       
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   SOFTWARE PACKAGES      : RELION, CTFFIND, COOT, REFMAC, RELION     
REMARK   3   RECONSTRUCTION SCHEMA  : NULL                                      
REMARK   3                                                                      
REMARK   3 EM MAP-MODEL FITTING AND REFINEMENT                                  
REMARK   3   PDB ENTRY                    : NULL                                
REMARK   3   REFINEMENT SPACE             : RECIPROCAL                          
REMARK   3   REFINEMENT PROTOCOL          : AB INITIO MODEL                     
REMARK   3   REFINEMENT TARGET            : NULL                                
REMARK   3   OVERALL ANISOTROPIC B VALUE  : NULL                                
REMARK   3                                                                      
REMARK   3 FITTING PROCEDURE : NULL                                             
REMARK   3                                                                      
REMARK   3 EM IMAGE RECONSTRUCTION STATISTICS                                   
REMARK   3   NOMINAL PIXEL SIZE (ANGSTROMS)    : NULL                           
REMARK   3   ACTUAL PIXEL SIZE  (ANGSTROMS)    : NULL                           
REMARK   3   EFFECTIVE RESOLUTION (ANGSTROMS)  : 3.600                          
REMARK   3   NUMBER OF PARTICLES               : 140155                         
REMARK   3   CTF CORRECTION METHOD             : PHASE FLIPPING ONLY            
REMARK   3                                                                      
REMARK   3 EM RECONSTRUCTION MAGNIFICATION CALIBRATION: NULL                    
REMARK   3                                                                      
REMARK   3 OTHER DETAILS: NULL                                                  
REMARK   4                                                                      
REMARK   4 5GAP COMPLIES WITH FORMAT V. 3.30, 13-JUL-11                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBE ON 08-JAN-16.                  
REMARK 100 THE DEPOSITION ID IS D_1001300034.                                   
REMARK 245                                                                      
REMARK 245 EXPERIMENTAL DETAILS                                                 
REMARK 245   RECONSTRUCTION METHOD          : SINGLE PARTICLE                   
REMARK 245   SPECIMEN TYPE                  : NULL                              
REMARK 245                                                                      
REMARK 245 ELECTRON MICROSCOPE SAMPLE                                           
REMARK 245   SAMPLE TYPE                    : PARTICLE                          
REMARK 245   PARTICLE TYPE                  : POINT                             
REMARK 245   NAME OF SAMPLE                 : BODY REGION OF THE U4/U6.U5 TRI   
REMARK 245                                    -SNRNP COMPLEX                    
REMARK 245   SAMPLE CONCENTRATION (MG ML-1) : 0.20                              
REMARK 245   SAMPLE SUPPORT DETAILS         : NULL                              
REMARK 245   SAMPLE VITRIFICATION DETAILS   : GRIDS WERE BLOTTED AT 4 DEG C     
REMARK 245                                    FOR 2 SECONDS BEFORE PLUNGING.    
REMARK 245   SAMPLE BUFFER                  : NULL                              
REMARK 245   PH                             : 7.90                              
REMARK 245   SAMPLE DETAILS                 : NULL                              
REMARK 245                                                                      
REMARK 245 DATA ACQUISITION                                                     
REMARK 245   DATE OF EXPERIMENT                : NULL                           
REMARK 245   NUMBER OF MICROGRAPHS-IMAGES      : 2477                           
REMARK 245   TEMPERATURE (KELVIN)              : NULL                           
REMARK 245   MICROSCOPE MODEL                  : FEI TITAN KRIOS                
REMARK 245   DETECTOR TYPE                     : GATAN K2 SUMMIT (4K X 4K)      
REMARK 245   MINIMUM DEFOCUS (NM)              : 500.00                         
REMARK 245   MAXIMUM DEFOCUS (NM)              : 3500.00                        
REMARK 245   MINIMUM TILT ANGLE (DEGREES)      : NULL                           
REMARK 245   MAXIMUM TILT ANGLE (DEGREES)      : NULL                           
REMARK 245   NOMINAL CS                        : 2.00                           
REMARK 245   IMAGING MODE                      : BRIGHT FIELD                   
REMARK 245   ELECTRON DOSE (ELECTRONS NM**-2)  : 38.00                          
REMARK 245   ILLUMINATION MODE                 : FLOOD BEAM                     
REMARK 245   NOMINAL MAGNIFICATION             : 81000                          
REMARK 245   CALIBRATED MAGNIFICATION          : 35714                          
REMARK 245   SOURCE                            : FIELD EMISSION GUN             
REMARK 245   ACCELERATION VOLTAGE (KV)         : 300                            
REMARK 245   IMAGING DETAILS                   : NULL                           
REMARK 247                                                                      
REMARK 247 ELECTRON MICROSCOPY                                                  
REMARK 247  THE COORDINATES IN THIS ENTRY WERE GENERATED FROM ELECTRON          
REMARK 247  MICROSCOPY DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE              
REMARK 247  THAT CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES           
REMARK 247  ON THESE RECORDS ARE MEANINGLESS EXCEPT FOR THE CALCULATION         
REMARK 247  OF THE STRUCTURE FACTORS.                                           
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY                                            
REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 1                              
REMARK 290                                                                      
REMARK 290      SYMOP   SYMMETRY                                                
REMARK 290     NNNMMM   OPERATOR                                                
REMARK 290       1555   X,Y,Z                                                   
REMARK 290                                                                      
REMARK 290     WHERE NNN -> OPERATOR NUMBER                                     
REMARK 290           MMM -> TRANSLATION VECTOR                                  
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS                            
REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM             
REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY                
REMARK 290 RELATED MOLECULES.                                                   
REMARK 290   SMTRY1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 290                                                                      
REMARK 290 REMARK: NULL                                                         
REMARK 300                                                                      
REMARK 300 BIOMOLECULE: 1                                                       
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM                
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN                  
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON               
REMARK 300 BURIED SURFACE AREA.                                                 
REMARK 350                                                                      
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN           
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE                
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS          
REMARK 350 GIVEN BELOW.  BOTH NON-CRYSTALLOGRAPHIC AND                          
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.                               
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 1                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: DODECAMERIC                       
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: DODECAMERIC                
REMARK 350 SOFTWARE USED: PISA                                                  
REMARK 350 TOTAL BURIED SURFACE AREA: 60560 ANGSTROM**2                         
REMARK 350 SURFACE AREA OF THE COMPLEX: 169960 ANGSTROM**2                      
REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -428.0 KCAL/MOL                       
REMARK 350 APPLY THE FOLLOWING TO CHAINS: V, W, U, x, A, H, J, D, F, G,         
REMARK 350                    AND CHAINS: K, B                                  
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 465                                                                      
REMARK 465 MISSING RESIDUES                                                     
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE                       
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)                
REMARK 465                                                                      
REMARK 465   M RES C SSSEQI                                                     
REMARK 465       G W     1                                                      
REMARK 465       U W     2                                                      
REMARK 465       U W     3                                                      
REMARK 465       C W     4                                                      
REMARK 465       G W     5                                                      
REMARK 465       C W     6                                                      
REMARK 465       G W     7                                                      
REMARK 465       A W     8                                                      
REMARK 465       A W     9                                                      
REMARK 465       G W    10                                                      
REMARK 465       U W    11                                                      
REMARK 465       A W    12                                                      
REMARK 465       A W    13                                                      
REMARK 465       C W    14                                                      
REMARK 465       C W    15                                                      
REMARK 465       C W    16                                                      
REMARK 465       U W    17                                                      
REMARK 465       U W    18                                                      
REMARK 465       C W    19                                                      
REMARK 465       G W    20                                                      
REMARK 465       U W    21                                                      
REMARK 465       G W    22                                                      
REMARK 465       G W    23                                                      
REMARK 465       A W    24                                                      
REMARK 465       C W    25                                                      
REMARK 465       A W    40                                                      
REMARK 465       A W    41                                                      
REMARK 465       A W    42                                                      
REMARK 465       C W    43                                                      
REMARK 465       G W    52                                                      
REMARK 465       A W    53                                                      
REMARK 465       U W    54                                                      
REMARK 465       U W    89                                                      
REMARK 465       U W    90                                                      
REMARK 465       A W    91                                                      
REMARK 465       C W    92                                                      
REMARK 465       A W    93                                                      
REMARK 465       A W    94                                                      
REMARK 465       A W    95                                                      
REMARK 465       G W    96                                                      
REMARK 465       A W    97                                                      
REMARK 465       G W    98                                                      
REMARK 465       A W    99                                                      
REMARK 465       U W   100                                                      
REMARK 465       U W   101                                                      
REMARK 465       U W   102                                                      
REMARK 465       A W   103                                                      
REMARK 465       U W   104                                                      
REMARK 465       U W   105                                                      
REMARK 465       U W   106                                                      
REMARK 465       C W   107                                                      
REMARK 465       G W   108                                                      
REMARK 465       U W   109                                                      
REMARK 465       U W   110                                                      
REMARK 465       U W   111                                                      
REMARK 465       U W   112                                                      
REMARK 465       A U     1                                                      
REMARK 465       A U     2                                                      
REMARK 465       G U     3                                                      
REMARK 465       C U     4                                                      
REMARK 465       A U     5                                                      
REMARK 465       G U     6                                                      
REMARK 465       C U     7                                                      
REMARK 465       U U     8                                                      
REMARK 465       U U     9                                                      
REMARK 465       U U    10                                                      
REMARK 465       A U    11                                                      
REMARK 465       C U    12                                                      
REMARK 465       A U    13                                                      
REMARK 465       G U    14                                                      
REMARK 465       A U    15                                                      
REMARK 465       U U    16                                                      
REMARK 465       C U    17                                                      
REMARK 465       A U    18                                                      
REMARK 465       A U    19                                                      
REMARK 465       U U    20                                                      
REMARK 465       G U    21                                                      
REMARK 465       G U    22                                                      
REMARK 465       C U    23                                                      
REMARK 465       G U    24                                                      
REMARK 465       G U    25                                                      
REMARK 465       A U    26                                                      
REMARK 465       G U    27                                                      
REMARK 465       G U    28                                                      
REMARK 465       G U    29                                                      
REMARK 465       A U    30                                                      
REMARK 465       G U    31                                                      
REMARK 465       G U    32                                                      
REMARK 465       U U    33                                                      
REMARK 465       C U    34                                                      
REMARK 465       A U    35                                                      
REMARK 465       A U    36                                                      
REMARK 465       C U    37                                                      
REMARK 465       A U    38                                                      
REMARK 465       U U    39                                                      
REMARK 465       C U    40                                                      
REMARK 465       A U    41                                                      
REMARK 465       A U    42                                                      
REMARK 465       G U    43                                                      
REMARK 465       A U    44                                                      
REMARK 465       A U    45                                                      
REMARK 465       C U    46                                                      
REMARK 465       U U    47                                                      
REMARK 465       G U    48                                                      
REMARK 465       U U    49                                                      
REMARK 465       G U    50                                                      
REMARK 465       G U    51                                                      
REMARK 465       G U    52                                                      
REMARK 465       C U    53                                                      
REMARK 465       C U    54                                                      
REMARK 465       U U    55                                                      
REMARK 465       U U    56                                                      
REMARK 465       U U    57                                                      
REMARK 465       U U    58                                                      
REMARK 465       A U    59                                                      
REMARK 465       U U    60                                                      
REMARK 465       U U    61                                                      
REMARK 465       G U    62                                                      
REMARK 465       C U    63                                                      
REMARK 465       C U    64                                                      
REMARK 465       U U    65                                                      
REMARK 465       A U    66                                                      
REMARK 465       U U    67                                                      
REMARK 465       A U    68                                                      
REMARK 465       G U    69                                                      
REMARK 465       A U    70                                                      
REMARK 465       A U    71                                                      
REMARK 465       C U    72                                                      
REMARK 465       U U    73                                                      
REMARK 465       U U    74                                                      
REMARK 465       A U    75                                                      
REMARK 465       U U    76                                                      
REMARK 465       A U    77                                                      
REMARK 465       A U    78                                                      
REMARK 465       C U    79                                                      
REMARK 465       G U    80                                                      
REMARK 465       A U    81                                                      
REMARK 465       A U    82                                                      
REMARK 465       C U    83                                                      
REMARK 465       A U    84                                                      
REMARK 465       U U    85                                                      
REMARK 465       G U    86                                                      
REMARK 465       G U    87                                                      
REMARK 465       C U   108                                                      
REMARK 465       A U   109                                                      
REMARK 465       U U   110                                                      
REMARK 465       C U   111                                                      
REMARK 465       C U   112                                                      
REMARK 465       G U   113                                                      
REMARK 465       G U   114                                                      
REMARK 465       G U   115                                                      
REMARK 465       U U   116                                                      
REMARK 465       G U   117                                                      
REMARK 465       U U   118                                                      
REMARK 465       U U   119                                                      
REMARK 465       G U   120                                                      
REMARK 465       U U   121                                                      
REMARK 465       C U   122                                                      
REMARK 465       U U   123                                                      
REMARK 465       C U   124                                                      
REMARK 465       C U   125                                                      
REMARK 465       A U   126                                                      
REMARK 465       U U   127                                                      
REMARK 465       A U   128                                                      
REMARK 465       G U   129                                                      
REMARK 465       A U   130                                                      
REMARK 465       A U   131                                                      
REMARK 465       A U   132                                                      
REMARK 465       C U   133                                                      
REMARK 465       A U   134                                                      
REMARK 465       G U   135                                                      
REMARK 465       G U   136                                                      
REMARK 465       U U   137                                                      
REMARK 465       A U   138                                                      
REMARK 465       A U   139                                                      
REMARK 465       A U   140                                                      
REMARK 465       G U   141                                                      
REMARK 465       C U   142                                                      
REMARK 465       U U   143                                                      
REMARK 465       G U   144                                                      
REMARK 465       U U   145                                                      
REMARK 465       C U   146                                                      
REMARK 465       C U   147                                                      
REMARK 465       G U   148                                                      
REMARK 465       U U   149                                                      
REMARK 465       U U   150                                                      
REMARK 465       A U   151                                                      
REMARK 465       C U   152                                                      
REMARK 465       U U   153                                                      
REMARK 465       G U   154                                                      
REMARK 465       U U   155                                                      
REMARK 465       G U   156                                                      
REMARK 465       G U   157                                                      
REMARK 465       G U   158                                                      
REMARK 465       C U   159                                                      
REMARK 465       U U   160                                                      
REMARK 465       U U   161                                                      
REMARK 465       G U   162                                                      
REMARK 465       C U   163                                                      
REMARK 465       C U   164                                                      
REMARK 465       A U   165                                                      
REMARK 465       U U   166                                                      
REMARK 465       A U   167                                                      
REMARK 465       U U   168                                                      
REMARK 465       U U   169                                                      
REMARK 465       U U   170                                                      
REMARK 465       U U   171                                                      
REMARK 465       U U   172                                                      
REMARK 465       U U   173                                                      
REMARK 465       G U   174                                                      
REMARK 465       G U   175                                                      
REMARK 465       A U   176                                                      
REMARK 465       A U   177                                                      
REMARK 465       C U   178                                                      
REMARK 465       U U   179                                                      
REMARK 465       U U   180                                                      
REMARK 465       U U   181                                                      
REMARK 465       U U   182                                                      
REMARK 465       C U   183                                                      
REMARK 465       U U   184                                                      
REMARK 465       G U   185                                                      
REMARK 465       C U   186                                                      
REMARK 465       C U   187                                                      
REMARK 465       C U   188                                                      
REMARK 465       U U   189                                                      
REMARK 465       U U   190                                                      
REMARK 465       U U   191                                                      
REMARK 465       U U   192                                                      
REMARK 465       U U   193                                                      
REMARK 465       C U   194                                                      
REMARK 465       U U   195                                                      
REMARK 465       C U   196                                                      
REMARK 465       A U   197                                                      
REMARK 465       A U   198                                                      
REMARK 465       U U   199                                                      
REMARK 465       G U   200                                                      
REMARK 465       A U   201                                                      
REMARK 465       G U   202                                                      
REMARK 465       U U   203                                                      
REMARK 465       A U   204                                                      
REMARK 465       A U   205                                                      
REMARK 465       G U   206                                                      
REMARK 465       G U   207                                                      
REMARK 465       A U   208                                                      
REMARK 465       G U   209                                                      
REMARK 465       G U   210                                                      
REMARK 465       G U   211                                                      
REMARK 465       C U   212                                                      
REMARK 465       G U   213                                                      
REMARK 465       U U   214                                                      
REMARK 465     MET A     1                                                      
REMARK 465     SER A     2                                                      
REMARK 465     GLY A     3                                                      
REMARK 465     LEU A     4                                                      
REMARK 465     PRO A     5                                                      
REMARK 465     PRO A     6                                                      
REMARK 465     PRO A     7                                                      
REMARK 465     PRO A     8                                                      
REMARK 465     PRO A     9                                                      
REMARK 465     GLY A    10                                                      
REMARK 465     PHE A    11                                                      
REMARK 465     GLU A    12                                                      
REMARK 465     GLU A    13                                                      
REMARK 465     ASP A    14                                                      
REMARK 465     SER A    15                                                      
REMARK 465     ASP A    16                                                      
REMARK 465     LEU A    17                                                      
REMARK 465     ALA A    18                                                      
REMARK 465     LEU A    19                                                      
REMARK 465     PRO A    20                                                      
REMARK 465     PRO A    21                                                      
REMARK 465     PRO A    22                                                      
REMARK 465     PRO A    23                                                      
REMARK 465     PRO A    24                                                      
REMARK 465     PRO A    25                                                      
REMARK 465     PRO A    26                                                      
REMARK 465     PRO A    27                                                      
REMARK 465     GLY A    28                                                      
REMARK 465     TYR A    29                                                      
REMARK 465     GLU A    30                                                      
REMARK 465     ILE A    31                                                      
REMARK 465     GLU A    32                                                      
REMARK 465     GLU A    33                                                      
REMARK 465     LEU A    34                                                      
REMARK 465     ASP A    35                                                      
REMARK 465     ASN A    36                                                      
REMARK 465     PRO A    37                                                      
REMARK 465     MET A    38                                                      
REMARK 465     VAL A    39                                                      
REMARK 465     PRO A    40                                                      
REMARK 465     SER A    41                                                      
REMARK 465     SER A    42                                                      
REMARK 465     VAL A    43                                                      
REMARK 465     ASN A    44                                                      
REMARK 465     GLU A    45                                                      
REMARK 465     ASP A    46                                                      
REMARK 465     THR A    47                                                      
REMARK 465     PHE A    48                                                      
REMARK 465     LEU A    49                                                      
REMARK 465     PRO A    50                                                      
REMARK 465     PRO A    51                                                      
REMARK 465     PRO A    52                                                      
REMARK 465     PRO A    53                                                      
REMARK 465     PRO A    54                                                      
REMARK 465     PRO A    55                                                      
REMARK 465     PRO A    56                                                      
REMARK 465     SER A    57                                                      
REMARK 465     ASN A    58                                                      
REMARK 465     PHE A    59                                                      
REMARK 465     GLU A    60                                                      
REMARK 465     ILE A    61                                                      
REMARK 465     ASN A    62                                                      
REMARK 465     ALA A    63                                                      
REMARK 465     GLU A    64                                                      
REMARK 465     GLU A    65                                                      
REMARK 465     ILE A    66                                                      
REMARK 465     VAL A    67                                                      
REMARK 465     ASP A    68                                                      
REMARK 465     PHE A    69                                                      
REMARK 465     THR A    70                                                      
REMARK 465     LEU A    71                                                      
REMARK 465     PRO A    72                                                      
REMARK 465     PRO A    73                                                      
REMARK 465     PRO A    74                                                      
REMARK 465     PRO A    75                                                      
REMARK 465     PRO A    76                                                      
REMARK 465     PRO A    77                                                      
REMARK 465     PRO A    78                                                      
REMARK 465     GLY A    79                                                      
REMARK 465     LEU A    80                                                      
REMARK 465     ASP A    81                                                      
REMARK 465     GLU A    82                                                      
REMARK 465     LEU A    83                                                      
REMARK 465     GLU A    84                                                      
REMARK 465     THR A    85                                                      
REMARK 465     LYS A    86                                                      
REMARK 465     ALA A    87                                                      
REMARK 465     GLU A    88                                                      
REMARK 465     LYS A    89                                                      
REMARK 465     LYS A    90                                                      
REMARK 465     VAL A    91                                                      
REMARK 465     GLU A    92                                                      
REMARK 465     LEU A    93                                                      
REMARK 465     HIS A    94                                                      
REMARK 465     GLY A    95                                                      
REMARK 465     LYS A    96                                                      
REMARK 465     ARG A    97                                                      
REMARK 465     LYS A    98                                                      
REMARK 465     LEU A    99                                                      
REMARK 465     ASP A   100                                                      
REMARK 465     ILE A   101                                                      
REMARK 465     GLY A   102                                                      
REMARK 465     LYS A   103                                                      
REMARK 465     ASP A   104                                                      
REMARK 465     THR A   105                                                      
REMARK 465     PHE A   106                                                      
REMARK 465     VAL A   107                                                      
REMARK 465     THR A   108                                                      
REMARK 465     ARG A   109                                                      
REMARK 465     LYS A   110                                                      
REMARK 465     SER A   111                                                      
REMARK 465     ARG A   112                                                      
REMARK 465     LYS A   113                                                      
REMARK 465     ARG A   114                                                      
REMARK 465     ALA A   115                                                      
REMARK 465     LYS A   116                                                      
REMARK 465     LYS A   117                                                      
REMARK 465     MET A   118                                                      
REMARK 465     THR A   119                                                      
REMARK 465     LYS A   120                                                      
REMARK 465     LYS A   121                                                      
REMARK 465     ALA A   122                                                      
REMARK 465     LYS A   123                                                      
REMARK 465     ARG A   124                                                      
REMARK 465     SER A   125                                                      
REMARK 465     ASN A   126                                                      
REMARK 465     LEU A   127                                                      
REMARK 465     TYR A   128                                                      
REMARK 465     THR A   129                                                      
REMARK 465     PRO A   130                                                      
REMARK 465     LYS A   131                                                      
REMARK 465     ALA A   132                                                      
REMARK 465     GLU A   133                                                      
REMARK 465     MET A   134                                                      
REMARK 465     PRO A   135                                                      
REMARK 465     PRO A   136                                                      
REMARK 465     GLU A   137                                                      
REMARK 465     HIS A   138                                                      
REMARK 465     LEU A   139                                                      
REMARK 465     ARG A   140                                                      
REMARK 465     LYS A   141                                                      
REMARK 465     ILE A   142                                                      
REMARK 465     ILE A   143                                                      
REMARK 465     ASN A   144                                                      
REMARK 465     THR A   145                                                      
REMARK 465     HIS A   146                                                      
REMARK 465     SER A   147                                                      
REMARK 465     ASP A   148                                                      
REMARK 465     MET A   149                                                      
REMARK 465     ALA A   150                                                      
REMARK 465     SER A   151                                                      
REMARK 465     LYS A   152                                                      
REMARK 465     MET A   153                                                      
REMARK 465     TYR A   154                                                      
REMARK 465     ASN A   155                                                      
REMARK 465     THR A   156                                                      
REMARK 465     ASP A   157                                                      
REMARK 465     LYS A   158                                                      
REMARK 465     LYS A   159                                                      
REMARK 465     ALA A   160                                                      
REMARK 465     PHE A   161                                                      
REMARK 465     LEU A   162                                                      
REMARK 465     GLY A   163                                                      
REMARK 465     ALA A   164                                                      
REMARK 465     LEU A   165                                                      
REMARK 465     LYS A   166                                                      
REMARK 465     TYR A   167                                                      
REMARK 465     LEU A   168                                                      
REMARK 465     PRO A   169                                                      
REMARK 465     HIS A   170                                                      
REMARK 465     ALA A   171                                                      
REMARK 465     ILE A   172                                                      
REMARK 465     LEU A   173                                                      
REMARK 465     LYS A   174                                                      
REMARK 465     LEU A   175                                                      
REMARK 465     LEU A   176                                                      
REMARK 465     GLU A   177                                                      
REMARK 465     ASN A   178                                                      
REMARK 465     MET A   179                                                      
REMARK 465     PRO A   180                                                      
REMARK 465     HIS A   181                                                      
REMARK 465     PRO A   182                                                      
REMARK 465     TRP A   183                                                      
REMARK 465     GLU A   184                                                      
REMARK 465     GLN A   185                                                      
REMARK 465     ALA A   186                                                      
REMARK 465     LYS A   187                                                      
REMARK 465     GLU A   188                                                      
REMARK 465     VAL A   189                                                      
REMARK 465     LYS A   190                                                      
REMARK 465     VAL A   191                                                      
REMARK 465     LEU A   192                                                      
REMARK 465     TYR A   193                                                      
REMARK 465     HIS A   194                                                      
REMARK 465     THR A   195                                                      
REMARK 465     SER A   196                                                      
REMARK 465     GLY A   197                                                      
REMARK 465     ALA A   198                                                      
REMARK 465     ILE A   199                                                      
REMARK 465     THR A   200                                                      
REMARK 465     PHE A   201                                                      
REMARK 465     VAL A   202                                                      
REMARK 465     ASN A   203                                                      
REMARK 465     GLU A   204                                                      
REMARK 465     THR A   205                                                      
REMARK 465     PRO A   206                                                      
REMARK 465     ARG A   207                                                      
REMARK 465     VAL A   208                                                      
REMARK 465     ILE A   209                                                      
REMARK 465     GLU A   210                                                      
REMARK 465     PRO A   211                                                      
REMARK 465     VAL A   212                                                      
REMARK 465     TYR A   213                                                      
REMARK 465     THR A   214                                                      
REMARK 465     ALA A   215                                                      
REMARK 465     GLN A   216                                                      
REMARK 465     TRP A   217                                                      
REMARK 465     SER A   218                                                      
REMARK 465     ALA A   219                                                      
REMARK 465     THR A   220                                                      
REMARK 465     TRP A   221                                                      
REMARK 465     ILE A   222                                                      
REMARK 465     ALA A   223                                                      
REMARK 465     MET A   224                                                      
REMARK 465     ARG A   225                                                      
REMARK 465     ARG A   226                                                      
REMARK 465     GLU A   227                                                      
REMARK 465     LYS A   228                                                      
REMARK 465     ARG A   229                                                      
REMARK 465     ASP A   230                                                      
REMARK 465     ARG A   231                                                      
REMARK 465     THR A   232                                                      
REMARK 465     HIS A   233                                                      
REMARK 465     PHE A   234                                                      
REMARK 465     LYS A   235                                                      
REMARK 465     ARG A   236                                                      
REMARK 465     MET A   237                                                      
REMARK 465     ARG A   238                                                      
REMARK 465     PHE A   239                                                      
REMARK 465     PRO A   240                                                      
REMARK 465     PRO A   241                                                      
REMARK 465     PHE A   242                                                      
REMARK 465     ASP A   243                                                      
REMARK 465     ASP A   244                                                      
REMARK 465     ASP A   245                                                      
REMARK 465     GLU A   246                                                      
REMARK 465     PRO A   247                                                      
REMARK 465     PRO A   248                                                      
REMARK 465     LEU A   249                                                      
REMARK 465     SER A   250                                                      
REMARK 465     TYR A   251                                                      
REMARK 465     GLU A   252                                                      
REMARK 465     GLN A   253                                                      
REMARK 465     HIS A   254                                                      
REMARK 465     ILE A   255                                                      
REMARK 465     GLU A   256                                                      
REMARK 465     ASN A   257                                                      
REMARK 465     ILE A   258                                                      
REMARK 465     GLU A   259                                                      
REMARK 465     PRO A   260                                                      
REMARK 465     LEU A   261                                                      
REMARK 465     ASP A   262                                                      
REMARK 465     PRO A   263                                                      
REMARK 465     ILE A   264                                                      
REMARK 465     ASN A   265                                                      
REMARK 465     LEU A   266                                                      
REMARK 465     PRO A   267                                                      
REMARK 465     LEU A   268                                                      
REMARK 465     ASP A   269                                                      
REMARK 465     SER A   270                                                      
REMARK 465     GLN A   271                                                      
REMARK 465     ASP A   272                                                      
REMARK 465     ASP A   273                                                      
REMARK 465     GLU A   274                                                      
REMARK 465     TYR A   275                                                      
REMARK 465     VAL A   276                                                      
REMARK 465     LYS A   277                                                      
REMARK 465     ASP A   278                                                      
REMARK 465     TRP A   279                                                      
REMARK 465     LEU A   280                                                      
REMARK 465     TYR A   281                                                      
REMARK 465     ASP A   282                                                      
REMARK 465     SER A   283                                                      
REMARK 465     ARG A   284                                                      
REMARK 465     PRO A   285                                                      
REMARK 465     LEU A   286                                                      
REMARK 465     GLU A   287                                                      
REMARK 465     GLU A   288                                                      
REMARK 465     ASP A   289                                                      
REMARK 465     SER A   290                                                      
REMARK 465     LYS A   291                                                      
REMARK 465     LYS A   292                                                      
REMARK 465     VAL A   293                                                      
REMARK 465     ASN A   294                                                      
REMARK 465     GLY A   295                                                      
REMARK 465     THR A   296                                                      
REMARK 465     SER A   297                                                      
REMARK 465     TYR A   298                                                      
REMARK 465     LYS A   299                                                      
REMARK 465     LYS A   300                                                      
REMARK 465     TRP A   301                                                      
REMARK 465     SER A   302                                                      
REMARK 465     PHE A   303                                                      
REMARK 465     ASP A   304                                                      
REMARK 465     LEU A   305                                                      
REMARK 465     PRO A   306                                                      
REMARK 465     GLU A   307                                                      
REMARK 465     MET A   308                                                      
REMARK 465     SER A   309                                                      
REMARK 465     ASN A   310                                                      
REMARK 465     LEU A   311                                                      
REMARK 465     TYR A   312                                                      
REMARK 465     ARG A   313                                                      
REMARK 465     LEU A   314                                                      
REMARK 465     SER A   315                                                      
REMARK 465     THR A   316                                                      
REMARK 465     PRO A   317                                                      
REMARK 465     LEU A   318                                                      
REMARK 465     ARG A   319                                                      
REMARK 465     ASP A   320                                                      
REMARK 465     GLU A   321                                                      
REMARK 465     VAL A   322                                                      
REMARK 465     THR A   323                                                      
REMARK 465     ASP A   324                                                      
REMARK 465     LYS A   325                                                      
REMARK 465     ASN A   326                                                      
REMARK 465     TYR A   327                                                      
REMARK 465     TYR A   328                                                      
REMARK 465     TYR A   329                                                      
REMARK 465     LEU A   330                                                      
REMARK 465     PHE A   331                                                      
REMARK 465     ASP A   332                                                      
REMARK 465     LYS A   333                                                      
REMARK 465     LYS A   334                                                      
REMARK 465     SER A   335                                                      
REMARK 465     PHE A   336                                                      
REMARK 465     PHE A   337                                                      
REMARK 465     ASN A   338                                                      
REMARK 465     GLY A   339                                                      
REMARK 465     LYS A   340                                                      
REMARK 465     ALA A   341                                                      
REMARK 465     LEU A   342                                                      
REMARK 465     ASN A   343                                                      
REMARK 465     ASN A   344                                                      
REMARK 465     ALA A   345                                                      
REMARK 465     ILE A   346                                                      
REMARK 465     PRO A   347                                                      
REMARK 465     GLY A   348                                                      
REMARK 465     GLY A   349                                                      
REMARK 465     PRO A   350                                                      
REMARK 465     LYS A   351                                                      
REMARK 465     PHE A   352                                                      
REMARK 465     GLU A   353                                                      
REMARK 465     PRO A   354                                                      
REMARK 465     LEU A   355                                                      
REMARK 465     TYR A   356                                                      
REMARK 465     PRO A   357                                                      
REMARK 465     ARG A   358                                                      
REMARK 465     GLU A   359                                                      
REMARK 465     GLU A   360                                                      
REMARK 465     GLU A   361                                                      
REMARK 465     GLU A   362                                                      
REMARK 465     ASP A   363                                                      
REMARK 465     TYR A   364                                                      
REMARK 465     ASN A   365                                                      
REMARK 465     GLU A   366                                                      
REMARK 465     PHE A   367                                                      
REMARK 465     ASN A   368                                                      
REMARK 465     SER A   369                                                      
REMARK 465     ILE A   370                                                      
REMARK 465     ASP A   371                                                      
REMARK 465     ARG A   372                                                      
REMARK 465     VAL A   373                                                      
REMARK 465     ILE A   374                                                      
REMARK 465     PHE A   375                                                      
REMARK 465     ARG A   376                                                      
REMARK 465     VAL A   377                                                      
REMARK 465     PRO A   378                                                      
REMARK 465     ILE A   379                                                      
REMARK 465     ARG A   380                                                      
REMARK 465     SER A   381                                                      
REMARK 465     GLU A   382                                                      
REMARK 465     TYR A   383                                                      
REMARK 465     LYS A   384                                                      
REMARK 465     VAL A   385                                                      
REMARK 465     ALA A   386                                                      
REMARK 465     PHE A   387                                                      
REMARK 465     PRO A   388                                                      
REMARK 465     HIS A   389                                                      
REMARK 465     LEU A   390                                                      
REMARK 465     TYR A   391                                                      
REMARK 465     ASN A   392                                                      
REMARK 465     SER A   393                                                      
REMARK 465     ARG A   394                                                      
REMARK 465     PRO A   395                                                      
REMARK 465     ARG A   396                                                      
REMARK 465     SER A   397                                                      
REMARK 465     VAL A   398                                                      
REMARK 465     ARG A   399                                                      
REMARK 465     ILE A   400                                                      
REMARK 465     PRO A   401                                                      
REMARK 465     TRP A   402                                                      
REMARK 465     TYR A   403                                                      
REMARK 465     ASN A   404                                                      
REMARK 465     ASN A   405                                                      
REMARK 465     PRO A   406                                                      
REMARK 465     VAL A   407                                                      
REMARK 465     SER A   408                                                      
REMARK 465     CYS A   409                                                      
REMARK 465     ILE A   410                                                      
REMARK 465     ILE A   411                                                      
REMARK 465     GLN A   412                                                      
REMARK 465     ASN A   413                                                      
REMARK 465     ASP A   414                                                      
REMARK 465     GLU A   415                                                      
REMARK 465     GLU A   416                                                      
REMARK 465     TYR A   417                                                      
REMARK 465     ASP A   418                                                      
REMARK 465     THR A   419                                                      
REMARK 465     PRO A   420                                                      
REMARK 465     ALA A   421                                                      
REMARK 465     LEU A   422                                                      
REMARK 465     PHE A   423                                                      
REMARK 465     PHE A   424                                                      
REMARK 465     ASP A   425                                                      
REMARK 465     PRO A   426                                                      
REMARK 465     SER A   427                                                      
REMARK 465     LEU A   428                                                      
REMARK 465     ASN A   429                                                      
REMARK 465     PRO A   430                                                      
REMARK 465     ILE A   431                                                      
REMARK 465     PRO A   432                                                      
REMARK 465     HIS A   433                                                      
REMARK 465     PHE A   434                                                      
REMARK 465     ILE A   435                                                      
REMARK 465     ASP A   436                                                      
REMARK 465     ASN A   437                                                      
REMARK 465     ASN A   438                                                      
REMARK 465     SER A   439                                                      
REMARK 465     SER A   440                                                      
REMARK 465     LEU A   441                                                      
REMARK 465     ASN A   442                                                      
REMARK 465     VAL A   443                                                      
REMARK 465     SER A   444                                                      
REMARK 465     ASN A   445                                                      
REMARK 465     THR A   446                                                      
REMARK 465     LYS A   447                                                      
REMARK 465     GLU A   448                                                      
REMARK 465     ASN A   449                                                      
REMARK 465     GLY A   450                                                      
REMARK 465     ASP A   451                                                      
REMARK 465     PHE A   452                                                      
REMARK 465     THR A   453                                                      
REMARK 465     LEU A   454                                                      
REMARK 465     PRO A   455                                                      
REMARK 465     GLU A   456                                                      
REMARK 465     ASP A   457                                                      
REMARK 465     PHE A   458                                                      
REMARK 465     ALA A   459                                                      
REMARK 465     PRO A   460                                                      
REMARK 465     LEU A   461                                                      
REMARK 465     LEU A   462                                                      
REMARK 465     ALA A   463                                                      
REMARK 465     GLU A   464                                                      
REMARK 465     GLU A   465                                                      
REMARK 465     GLU A   466                                                      
REMARK 465     GLU A   467                                                      
REMARK 465     LEU A   468                                                      
REMARK 465     ILE A   469                                                      
REMARK 465     LEU A   470                                                      
REMARK 465     PRO A   471                                                      
REMARK 465     ASN A   472                                                      
REMARK 465     THR A   473                                                      
REMARK 465     LYS A   474                                                      
REMARK 465     ASP A   475                                                      
REMARK 465     ALA A   476                                                      
REMARK 465     MET A   477                                                      
REMARK 465     SER A   478                                                      
REMARK 465     LEU A   479                                                      
REMARK 465     TYR A   480                                                      
REMARK 465     HIS A   481                                                      
REMARK 465     SER A   482                                                      
REMARK 465     PRO A   483                                                      
REMARK 465     PHE A   484                                                      
REMARK 465     PRO A   485                                                      
REMARK 465     PHE A   486                                                      
REMARK 465     ASN A   487                                                      
REMARK 465     ARG A   488                                                      
REMARK 465     THR A   489                                                      
REMARK 465     LYS A   490                                                      
REMARK 465     GLY A   491                                                      
REMARK 465     LYS A   492                                                      
REMARK 465     MET A   493                                                      
REMARK 465     VAL A   494                                                      
REMARK 465     ARG A   495                                                      
REMARK 465     ALA A   496                                                      
REMARK 465     GLN A   497                                                      
REMARK 465     ASP A   498                                                      
REMARK 465     VAL A   499                                                      
REMARK 465     ALA A   500                                                      
REMARK 465     LEU A   501                                                      
REMARK 465     ALA A   502                                                      
REMARK 465     LYS A   503                                                      
REMARK 465     LYS A   504                                                      
REMARK 465     TRP A   505                                                      
REMARK 465     PHE A   506                                                      
REMARK 465     LEU A   507                                                      
REMARK 465     GLN A   508                                                      
REMARK 465     HIS A   509                                                      
REMARK 465     PRO A   510                                                      
REMARK 465     ASP A   511                                                      
REMARK 465     GLU A   512                                                      
REMARK 465     GLU A   513                                                      
REMARK 465     TYR A   514                                                      
REMARK 465     PRO A   515                                                      
REMARK 465     VAL A   516                                                      
REMARK 465     LYS A   517                                                      
REMARK 465     VAL A   518                                                      
REMARK 465     LYS A   519                                                      
REMARK 465     VAL A   520                                                      
REMARK 465     SER A   521                                                      
REMARK 465     TYR A   522                                                      
REMARK 465     GLN A   523                                                      
REMARK 465     LYS A   524                                                      
REMARK 465     LEU A   525                                                      
REMARK 465     LEU A   526                                                      
REMARK 465     LYS A   527                                                      
REMARK 465     ASN A   528                                                      
REMARK 465     TYR A   529                                                      
REMARK 465     VAL A   530                                                      
REMARK 465     LEU A   531                                                      
REMARK 465     ASN A   532                                                      
REMARK 465     GLU A   533                                                      
REMARK 465     LEU A   534                                                      
REMARK 465     HIS A   535                                                      
REMARK 465     PRO A   536                                                      
REMARK 465     THR A   537                                                      
REMARK 465     LEU A   538                                                      
REMARK 465     PRO A   539                                                      
REMARK 465     THR A   540                                                      
REMARK 465     ASN A   541                                                      
REMARK 465     HIS A   542                                                      
REMARK 465     ASN A   543                                                      
REMARK 465     LYS A   544                                                      
REMARK 465     THR A   545                                                      
REMARK 465     LYS A   546                                                      
REMARK 465     LEU A   547                                                      
REMARK 465     LEU A   548                                                      
REMARK 465     LYS A   549                                                      
REMARK 465     SER A   550                                                      
REMARK 465     LEU A   551                                                      
REMARK 465     LYS A   552                                                      
REMARK 465     ASN A   553                                                      
REMARK 465     THR A   554                                                      
REMARK 465     LYS A   555                                                      
REMARK 465     TYR A   556                                                      
REMARK 465     PHE A   557                                                      
REMARK 465     GLN A   558                                                      
REMARK 465     GLN A   559                                                      
REMARK 465     THR A   560                                                      
REMARK 465     THR A   561                                                      
REMARK 465     ILE A   562                                                      
REMARK 465     ASP A   563                                                      
REMARK 465     TRP A   564                                                      
REMARK 465     VAL A   565                                                      
REMARK 465     GLU A   566                                                      
REMARK 465     ALA A   567                                                      
REMARK 465     GLY A   568                                                      
REMARK 465     LEU A   569                                                      
REMARK 465     GLN A   570                                                      
REMARK 465     LEU A   571                                                      
REMARK 465     CYS A   572                                                      
REMARK 465     ARG A   573                                                      
REMARK 465     GLN A   574                                                      
REMARK 465     GLY A   575                                                      
REMARK 465     HIS A   576                                                      
REMARK 465     ASN A   577                                                      
REMARK 465     MET A   578                                                      
REMARK 465     LEU A   579                                                      
REMARK 465     ASN A   580                                                      
REMARK 465     LEU A   581                                                      
REMARK 465     LEU A   582                                                      
REMARK 465     ILE A   583                                                      
REMARK 465     HIS A   584                                                      
REMARK 465     ARG A   585                                                      
REMARK 465     LYS A   586                                                      
REMARK 465     GLY A   587                                                      
REMARK 465     LEU A   588                                                      
REMARK 465     THR A   589                                                      
REMARK 465     TYR A   590                                                      
REMARK 465     LEU A   591                                                      
REMARK 465     HIS A   592                                                      
REMARK 465     LEU A   593                                                      
REMARK 465     ASP A   594                                                      
REMARK 465     TYR A   595                                                      
REMARK 465     ASN A   596                                                      
REMARK 465     PHE A   597                                                      
REMARK 465     ASN A   598                                                      
REMARK 465     LEU A   599                                                      
REMARK 465     LYS A   600                                                      
REMARK 465     PRO A   601                                                      
REMARK 465     THR A   602                                                      
REMARK 465     LYS A   603                                                      
REMARK 465     THR A   604                                                      
REMARK 465     LEU A   605                                                      
REMARK 465     THR A   606                                                      
REMARK 465     THR A   607                                                      
REMARK 465     LYS A   608                                                      
REMARK 465     GLU A   609                                                      
REMARK 465     ARG A   610                                                      
REMARK 465     LYS A   611                                                      
REMARK 465     LYS A   612                                                      
REMARK 465     SER A   613                                                      
REMARK 465     ARG A   614                                                      
REMARK 465     LEU A   615                                                      
REMARK 465     GLY A   616                                                      
REMARK 465     ASN A   617                                                      
REMARK 465     SER A   618                                                      
REMARK 465     PHE A   619                                                      
REMARK 465     HIS A   620                                                      
REMARK 465     LEU A   621                                                      
REMARK 465     MET A   622                                                      
REMARK 465     ARG A   623                                                      
REMARK 465     GLU A   624                                                      
REMARK 465     LEU A   625                                                      
REMARK 465     LEU A   626                                                      
REMARK 465     LYS A   627                                                      
REMARK 465     MET A   628                                                      
REMARK 465     MET A   629                                                      
REMARK 465     LYS A   630                                                      
REMARK 465     LEU A   631                                                      
REMARK 465     ILE A   632                                                      
REMARK 465     VAL A   633                                                      
REMARK 465     ASP A   634                                                      
REMARK 465     THR A   635                                                      
REMARK 465     HIS A   636                                                      
REMARK 465     VAL A   637                                                      
REMARK 465     GLN A   638                                                      
REMARK 465     PHE A   639                                                      
REMARK 465     ARG A   640                                                      
REMARK 465     LEU A   641                                                      
REMARK 465     GLY A   642                                                      
REMARK 465     ASN A   643                                                      
REMARK 465     VAL A   644                                                      
REMARK 465     ASP A   645                                                      
REMARK 465     ALA A   646                                                      
REMARK 465     PHE A   647                                                      
REMARK 465     GLN A   648                                                      
REMARK 465     LEU A   649                                                      
REMARK 465     ALA A   650                                                      
REMARK 465     ASP A   651                                                      
REMARK 465     GLY A   652                                                      
REMARK 465     ILE A   653                                                      
REMARK 465     HIS A   654                                                      
REMARK 465     TYR A   655                                                      
REMARK 465     ILE A   656                                                      
REMARK 465     LEU A   657                                                      
REMARK 465     ASN A   658                                                      
REMARK 465     HIS A   659                                                      
REMARK 465     ILE A   660                                                      
REMARK 465     GLY A   661                                                      
REMARK 465     GLN A   662                                                      
REMARK 465     LEU A   663                                                      
REMARK 465     THR A   664                                                      
REMARK 465     GLY A   665                                                      
REMARK 465     ILE A   666                                                      
REMARK 465     TYR A   667                                                      
REMARK 465     ARG A   668                                                      
REMARK 465     TYR A   669                                                      
REMARK 465     LYS A   670                                                      
REMARK 465     TYR A   671                                                      
REMARK 465     LYS A   672                                                      
REMARK 465     VAL A   673                                                      
REMARK 465     MET A   674                                                      
REMARK 465     HIS A   675                                                      
REMARK 465     GLN A   676                                                      
REMARK 465     ILE A   677                                                      
REMARK 465     ARG A   678                                                      
REMARK 465     ALA A   679                                                      
REMARK 465     CYS A   680                                                      
REMARK 465     LYS A   681                                                      
REMARK 465     ASP A   682                                                      
REMARK 465     LEU A   683                                                      
REMARK 465     LYS A   684                                                      
REMARK 465     HIS A   685                                                      
REMARK 465     ILE A   686                                                      
REMARK 465     ILE A   687                                                      
REMARK 465     TYR A   688                                                      
REMARK 465     TYR A   689                                                      
REMARK 465     LYS A   690                                                      
REMARK 465     PHE A   691                                                      
REMARK 465     ASN A   692                                                      
REMARK 465     LYS A   693                                                      
REMARK 465     ASN A   694                                                      
REMARK 465     LEU A   695                                                      
REMARK 465     GLY A   696                                                      
REMARK 465     LYS A   697                                                      
REMARK 465     GLY A   698                                                      
REMARK 465     PRO A   699                                                      
REMARK 465     GLY A   700                                                      
REMARK 465     CYS A   701                                                      
REMARK 465     GLY A   702                                                      
REMARK 465     PHE A   703                                                      
REMARK 465     TRP A   704                                                      
REMARK 465     GLN A   705                                                      
REMARK 465     PRO A   706                                                      
REMARK 465     ALA A   707                                                      
REMARK 465     TRP A   708                                                      
REMARK 465     ARG A   709                                                      
REMARK 465     VAL A   710                                                      
REMARK 465     TRP A   711                                                      
REMARK 465     LEU A   712                                                      
REMARK 465     ASN A   713                                                      
REMARK 465     PHE A   714                                                      
REMARK 465     LEU A   715                                                      
REMARK 465     ARG A   716                                                      
REMARK 465     GLY A   717                                                      
REMARK 465     THR A   718                                                      
REMARK 465     ILE A   719                                                      
REMARK 465     PRO A   720                                                      
REMARK 465     LEU A   721                                                      
REMARK 465     LEU A   722                                                      
REMARK 465     GLU A   723                                                      
REMARK 465     ARG A   724                                                      
REMARK 465     TYR A   725                                                      
REMARK 465     ILE A   726                                                      
REMARK 465     GLY A   727                                                      
REMARK 465     ASN A   728                                                      
REMARK 465     LEU A   729                                                      
REMARK 465     ILE A   730                                                      
REMARK 465     THR A   731                                                      
REMARK 465     ARG A   732                                                      
REMARK 465     GLN A   733                                                      
REMARK 465     PHE A   734                                                      
REMARK 465     GLU A   735                                                      
REMARK 465     GLY A   736                                                      
REMARK 465     ARG A   737                                                      
REMARK 465     SER A   738                                                      
REMARK 465     ASN A   739                                                      
REMARK 465     GLU A   740                                                      
REMARK 465     ILE A   741                                                      
REMARK 465     VAL A   742                                                      
REMARK 465     LYS A   743                                                      
REMARK 465     THR A   744                                                      
REMARK 465     THR A   745                                                      
REMARK 465     THR A   746                                                      
REMARK 465     LYS A   747                                                      
REMARK 465     GLN A   748                                                      
REMARK 465     ARG A   749                                                      
REMARK 465     LEU A   750                                                      
REMARK 465     GLY A  1428                                                      
REMARK 465     MET A  1429                                                      
REMARK 465     THR A  1430                                                      
REMARK 465     HIS A  1431                                                      
REMARK 465     GLU A  1432                                                      
REMARK 465     ARG A  2105                                                      
REMARK 465     SER A  2106                                                      
REMARK 465     GLU A  2107                                                      
REMARK 465     LYS A  2108                                                      
REMARK 465     GLN A  2109                                                      
REMARK 465     ASN A  2110                                                      
REMARK 465     ASP A  2111                                                      
REMARK 465     GLU A  2112                                                      
REMARK 465     GLU A  2113                                                      
REMARK 465     ALA A  2114                                                      
REMARK 465     ALA A  2115                                                      
REMARK 465     GLY A  2116                                                      
REMARK 465     ALA A  2117                                                      
REMARK 465     SER A  2118                                                      
REMARK 465     THR A  2119                                                      
REMARK 465     VAL A  2120                                                      
REMARK 465     MET A  2121                                                      
REMARK 465     LYS A  2122                                                      
REMARK 465     THR A  2123                                                      
REMARK 465     LYS A  2124                                                      
REMARK 465     THR A  2125                                                      
REMARK 465     ILE A  2126                                                      
REMARK 465     ASN A  2127                                                      
REMARK 465     ALA A  2128                                                      
REMARK 465     GLN A  2129                                                      
REMARK 465     GLY A  2130                                                      
REMARK 465     GLU A  2131                                                      
REMARK 465     GLU A  2132                                                      
REMARK 465     ILE A  2133                                                      
REMARK 465     VAL A  2134                                                      
REMARK 465     VAL A  2135                                                      
REMARK 465     VAL A  2136                                                      
REMARK 465     ALA A  2137                                                      
REMARK 465     SER A  2138                                                      
REMARK 465     ALA A  2139                                                      
REMARK 465     ASP A  2140                                                      
REMARK 465     TYR A  2141                                                      
REMARK 465     GLU A  2142                                                      
REMARK 465     SER A  2143                                                      
REMARK 465     GLN A  2144                                                      
REMARK 465     THR A  2145                                                      
REMARK 465     PHE A  2146                                                      
REMARK 465     SER A  2147                                                      
REMARK 465     SER A  2148                                                      
REMARK 465     LYS A  2149                                                      
REMARK 465     ASN A  2150                                                      
REMARK 465     GLU A  2151                                                      
REMARK 465     TRP A  2152                                                      
REMARK 465     ARG A  2153                                                      
REMARK 465     LYS A  2154                                                      
REMARK 465     SER A  2155                                                      
REMARK 465     ALA A  2156                                                      
REMARK 465     ILE A  2157                                                      
REMARK 465     ALA A  2158                                                      
REMARK 465     ASN A  2159                                                      
REMARK 465     THR A  2160                                                      
REMARK 465     LEU A  2161                                                      
REMARK 465     LEU A  2162                                                      
REMARK 465     TYR A  2163                                                      
REMARK 465     LEU A  2164                                                      
REMARK 465     ARG A  2165                                                      
REMARK 465     LEU A  2166                                                      
REMARK 465     LYS A  2167                                                      
REMARK 465     ASN A  2168                                                      
REMARK 465     ILE A  2169                                                      
REMARK 465     TYR A  2170                                                      
REMARK 465     VAL A  2171                                                      
REMARK 465     SER A  2172                                                      
REMARK 465     ALA A  2173                                                      
REMARK 465     ASP A  2174                                                      
REMARK 465     ASP A  2175                                                      
REMARK 465     PHE A  2176                                                      
REMARK 465     VAL A  2177                                                      
REMARK 465     GLU A  2178                                                      
REMARK 465     GLU A  2179                                                      
REMARK 465     GLN A  2180                                                      
REMARK 465     ASN A  2181                                                      
REMARK 465     VAL A  2182                                                      
REMARK 465     TYR A  2183                                                      
REMARK 465     VAL A  2184                                                      
REMARK 465     LEU A  2185                                                      
REMARK 465     PRO A  2186                                                      
REMARK 465     LYS A  2187                                                      
REMARK 465     ASN A  2188                                                      
REMARK 465     LEU A  2189                                                      
REMARK 465     LEU A  2190                                                      
REMARK 465     LYS A  2191                                                      
REMARK 465     LYS A  2192                                                      
REMARK 465     PHE A  2193                                                      
REMARK 465     ILE A  2194                                                      
REMARK 465     GLU A  2195                                                      
REMARK 465     ILE A  2196                                                      
REMARK 465     SER A  2197                                                      
REMARK 465     ASP A  2198                                                      
REMARK 465     VAL A  2199                                                      
REMARK 465     LYS A  2200                                                      
REMARK 465     ILE A  2201                                                      
REMARK 465     GLN A  2202                                                      
REMARK 465     VAL A  2203                                                      
REMARK 465     ALA A  2204                                                      
REMARK 465     ALA A  2205                                                      
REMARK 465     PHE A  2206                                                      
REMARK 465     ILE A  2207                                                      
REMARK 465     TYR A  2208                                                      
REMARK 465     GLY A  2209                                                      
REMARK 465     MET A  2210                                                      
REMARK 465     SER A  2211                                                      
REMARK 465     ALA A  2212                                                      
REMARK 465     LYS A  2213                                                      
REMARK 465     ASP A  2214                                                      
REMARK 465     HIS A  2215                                                      
REMARK 465     PRO A  2216                                                      
REMARK 465     LYS A  2217                                                      
REMARK 465     VAL A  2218                                                      
REMARK 465     LYS A  2219                                                      
REMARK 465     GLU A  2220                                                      
REMARK 465     ILE A  2221                                                      
REMARK 465     LYS A  2222                                                      
REMARK 465     THR A  2223                                                      
REMARK 465     VAL A  2224                                                      
REMARK 465     VAL A  2225                                                      
REMARK 465     LEU A  2226                                                      
REMARK 465     VAL A  2227                                                      
REMARK 465     PRO A  2228                                                      
REMARK 465     GLN A  2229                                                      
REMARK 465     LEU A  2230                                                      
REMARK 465     GLY A  2231                                                      
REMARK 465     HIS A  2232                                                      
REMARK 465     VAL A  2233                                                      
REMARK 465     GLY A  2234                                                      
REMARK 465     SER A  2235                                                      
REMARK 465     VAL A  2236                                                      
REMARK 465     GLN A  2237                                                      
REMARK 465     ILE A  2238                                                      
REMARK 465     SER A  2239                                                      
REMARK 465     ASN A  2240                                                      
REMARK 465     ILE A  2241                                                      
REMARK 465     PRO A  2242                                                      
REMARK 465     ASP A  2243                                                      
REMARK 465     ILE A  2244                                                      
REMARK 465     GLY A  2245                                                      
REMARK 465     ASP A  2246                                                      
REMARK 465     LEU A  2247                                                      
REMARK 465     PRO A  2248                                                      
REMARK 465     ASP A  2249                                                      
REMARK 465     THR A  2250                                                      
REMARK 465     GLU A  2251                                                      
REMARK 465     GLY A  2252                                                      
REMARK 465     LEU A  2253                                                      
REMARK 465     GLU A  2254                                                      
REMARK 465     LEU A  2255                                                      
REMARK 465     LEU A  2256                                                      
REMARK 465     GLY A  2257                                                      
REMARK 465     TRP A  2258                                                      
REMARK 465     ILE A  2259                                                      
REMARK 465     HIS A  2260                                                      
REMARK 465     THR A  2261                                                      
REMARK 465     GLN A  2262                                                      
REMARK 465     THR A  2263                                                      
REMARK 465     GLU A  2264                                                      
REMARK 465     GLU A  2265                                                      
REMARK 465     LEU A  2266                                                      
REMARK 465     LYS A  2267                                                      
REMARK 465     PHE A  2268                                                      
REMARK 465     MET A  2269                                                      
REMARK 465     ALA A  2270                                                      
REMARK 465     ALA A  2271                                                      
REMARK 465     SER A  2272                                                      
REMARK 465     GLU A  2273                                                      
REMARK 465     VAL A  2274                                                      
REMARK 465     ALA A  2275                                                      
REMARK 465     THR A  2276                                                      
REMARK 465     HIS A  2277                                                      
REMARK 465     SER A  2278                                                      
REMARK 465     LYS A  2279                                                      
REMARK 465     LEU A  2280                                                      
REMARK 465     PHE A  2281                                                      
REMARK 465     ALA A  2282                                                      
REMARK 465     ASP A  2283                                                      
REMARK 465     LYS A  2284                                                      
REMARK 465     LYS A  2285                                                      
REMARK 465     ARG A  2286                                                      
REMARK 465     ASP A  2287                                                      
REMARK 465     CYS A  2288                                                      
REMARK 465     ILE A  2289                                                      
REMARK 465     ASP A  2290                                                      
REMARK 465     ILE A  2291                                                      
REMARK 465     SER A  2292                                                      
REMARK 465     ILE A  2293                                                      
REMARK 465     PHE A  2294                                                      
REMARK 465     SER A  2295                                                      
REMARK 465     THR A  2296                                                      
REMARK 465     PRO A  2297                                                      
REMARK 465     GLY A  2298                                                      
REMARK 465     SER A  2299                                                      
REMARK 465     VAL A  2300                                                      
REMARK 465     SER A  2301                                                      
REMARK 465     LEU A  2302                                                      
REMARK 465     SER A  2303                                                      
REMARK 465     ALA A  2304                                                      
REMARK 465     TYR A  2305                                                      
REMARK 465     ASN A  2306                                                      
REMARK 465     LEU A  2307                                                      
REMARK 465     THR A  2308                                                      
REMARK 465     ASP A  2309                                                      
REMARK 465     GLU A  2310                                                      
REMARK 465     GLY A  2311                                                      
REMARK 465     TYR A  2312                                                      
REMARK 465     GLN A  2313                                                      
REMARK 465     TRP A  2314                                                      
REMARK 465     GLY A  2315                                                      
REMARK 465     GLU A  2316                                                      
REMARK 465     GLU A  2317                                                      
REMARK 465     ASN A  2318                                                      
REMARK 465     LYS A  2319                                                      
REMARK 465     ASP A  2320                                                      
REMARK 465     ILE A  2321                                                      
REMARK 465     MET A  2322                                                      
REMARK 465     ASN A  2323                                                      
REMARK 465     VAL A  2324                                                      
REMARK 465     LEU A  2325                                                      
REMARK 465     SER A  2326                                                      
REMARK 465     GLU A  2327                                                      
REMARK 465     GLY A  2328                                                      
REMARK 465     PHE A  2329                                                      
REMARK 465     GLU A  2330                                                      
REMARK 465     PRO A  2331                                                      
REMARK 465     THR A  2332                                                      
REMARK 465     PHE A  2333                                                      
REMARK 465     SER A  2334                                                      
REMARK 465     THR A  2335                                                      
REMARK 465     HIS A  2336                                                      
REMARK 465     ALA A  2337                                                      
REMARK 465     GLN A  2338                                                      
REMARK 465     LEU A  2339                                                      
REMARK 465     LEU A  2340                                                      
REMARK 465     LEU A  2341                                                      
REMARK 465     SER A  2342                                                      
REMARK 465     ASP A  2343                                                      
REMARK 465     ARG A  2344                                                      
REMARK 465     ILE A  2345                                                      
REMARK 465     THR A  2346                                                      
REMARK 465     GLY A  2347                                                      
REMARK 465     ASN A  2348                                                      
REMARK 465     PHE A  2349                                                      
REMARK 465     ILE A  2350                                                      
REMARK 465     ILE A  2351                                                      
REMARK 465     PRO A  2352                                                      
REMARK 465     SER A  2353                                                      
REMARK 465     GLY A  2354                                                      
REMARK 465     ASN A  2355                                                      
REMARK 465     VAL A  2356                                                      
REMARK 465     TRP A  2357                                                      
REMARK 465     ASN A  2358                                                      
REMARK 465     TYR A  2359                                                      
REMARK 465     THR A  2360                                                      
REMARK 465     PHE A  2361                                                      
REMARK 465     MET A  2362                                                      
REMARK 465     GLY A  2363                                                      
REMARK 465     THR A  2364                                                      
REMARK 465     ALA A  2365                                                      
REMARK 465     PHE A  2366                                                      
REMARK 465     ASN A  2367                                                      
REMARK 465     GLN A  2368                                                      
REMARK 465     GLU A  2369                                                      
REMARK 465     GLY A  2370                                                      
REMARK 465     ASP A  2371                                                      
REMARK 465     TYR A  2372                                                      
REMARK 465     ASN A  2373                                                      
REMARK 465     PHE A  2374                                                      
REMARK 465     LYS A  2375                                                      
REMARK 465     TYR A  2376                                                      
REMARK 465     GLY A  2377                                                      
REMARK 465     ILE A  2378                                                      
REMARK 465     PRO A  2379                                                      
REMARK 465     LEU A  2380                                                      
REMARK 465     GLU A  2381                                                      
REMARK 465     PHE A  2382                                                      
REMARK 465     TYR A  2383                                                      
REMARK 465     ASN A  2384                                                      
REMARK 465     GLU A  2385                                                      
REMARK 465     MET A  2386                                                      
REMARK 465     HIS A  2387                                                      
REMARK 465     ARG A  2388                                                      
REMARK 465     PRO A  2389                                                      
REMARK 465     VAL A  2390                                                      
REMARK 465     HIS A  2391                                                      
REMARK 465     PHE A  2392                                                      
REMARK 465     LEU A  2393                                                      
REMARK 465     GLN A  2394                                                      
REMARK 465     PHE A  2395                                                      
REMARK 465     SER A  2396                                                      
REMARK 465     GLU A  2397                                                      
REMARK 465     LEU A  2398                                                      
REMARK 465     ALA A  2399                                                      
REMARK 465     GLY A  2400                                                      
REMARK 465     ASP A  2401                                                      
REMARK 465     GLU A  2402                                                      
REMARK 465     GLU A  2403                                                      
REMARK 465     LEU A  2404                                                      
REMARK 465     GLU A  2405                                                      
REMARK 465     ALA A  2406                                                      
REMARK 465     GLU A  2407                                                      
REMARK 465     GLN A  2408                                                      
REMARK 465     ILE A  2409                                                      
REMARK 465     ASP A  2410                                                      
REMARK 465     VAL A  2411                                                      
REMARK 465     PHE A  2412                                                      
REMARK 465     SER A  2413                                                      
REMARK 465     MET H     1                                                      
REMARK 465     SER H     2                                                      
REMARK 465     LYS H     3                                                      
REMARK 465     TYR H     4                                                      
REMARK 465     ILE H     5                                                      
REMARK 465     ALA H     6                                                      
REMARK 465     LEU H     7                                                      
REMARK 465     GLU H     8                                                      
REMARK 465     ASN H     9                                                      
REMARK 465     LEU H    10                                                      
REMARK 465     PRO H    11                                                      
REMARK 465     VAL H    12                                                      
REMARK 465     ASP H    13                                                      
REMARK 465     LEU H    14                                                      
REMARK 465     GLN H    15                                                      
REMARK 465     HIS H    16                                                      
REMARK 465     LYS H    17                                                      
REMARK 465     GLY H    18                                                      
REMARK 465     ALA H    19                                                      
REMARK 465     THR H    20                                                      
REMARK 465     GLN H    21                                                      
REMARK 465     ASN H    22                                                      
REMARK 465     GLU H    23                                                      
REMARK 465     SER H    24                                                      
REMARK 465     THR H    25                                                      
REMARK 465     ALA H    26                                                      
REMARK 465     ASP H    27                                                      
REMARK 465     ILE H    28                                                      
REMARK 465     LEU H    29                                                      
REMARK 465     LYS H    30                                                      
REMARK 465     GLN H    31                                                      
REMARK 465     LEU H    32                                                      
REMARK 465     PRO H    33                                                      
REMARK 465     HIS H    34                                                      
REMARK 465     GLU H    35                                                      
REMARK 465     ARG H    36                                                      
REMARK 465     LEU H    37                                                      
REMARK 465     GLN H    38                                                      
REMARK 465     ALA H    39                                                      
REMARK 465     VAL H    40                                                      
REMARK 465     LEU H    41                                                      
REMARK 465     GLU H    42                                                      
REMARK 465     LYS H    43                                                      
REMARK 465     ILE H    44                                                      
REMARK 465     PRO H    45                                                      
REMARK 465     GLU H    46                                                      
REMARK 465     GLU H    47                                                      
REMARK 465     ASP H    48                                                      
REMARK 465     LEU H    49                                                      
REMARK 465     GLU H    50                                                      
REMARK 465     VAL H    51                                                      
REMARK 465     ARG H    52                                                      
REMARK 465     ARG H    53                                                      
REMARK 465     LEU H    54                                                      
REMARK 465     LEU H    55                                                      
REMARK 465     SER H    56                                                      
REMARK 465     ILE H    57                                                      
REMARK 465     LEU H    58                                                      
REMARK 465     LYS H    59                                                      
REMARK 465     LYS H    60                                                      
REMARK 465     PRO H    61                                                      
REMARK 465     GLU H    62                                                      
REMARK 465     VAL H    63                                                      
REMARK 465     VAL H    64                                                      
REMARK 465     GLU H    65                                                      
REMARK 465     ASN H    66                                                      
REMARK 465     GLU H    67                                                      
REMARK 465     ASP H    68                                                      
REMARK 465     VAL H    69                                                      
REMARK 465     GLN H    70                                                      
REMARK 465     GLN H    71                                                      
REMARK 465     ARG H    72                                                      
REMARK 465     ARG H    73                                                      
REMARK 465     ILE H    74                                                      
REMARK 465     ARG H    75                                                      
REMARK 465     LEU H    76                                                      
REMARK 465     ALA H    77                                                      
REMARK 465     GLU H    78                                                      
REMARK 465     ILE H    79                                                      
REMARK 465     LEU H    80                                                      
REMARK 465     MET H    81                                                      
REMARK 465     VAL H    82                                                      
REMARK 465     ASP H    83                                                      
REMARK 465     GLU H    84                                                      
REMARK 465     ILE H    85                                                      
REMARK 465     ASP H    86                                                      
REMARK 465     LEU H    87                                                      
REMARK 465     GLU H    88                                                      
REMARK 465     ASN H    89                                                      
REMARK 465     ILE H    90                                                      
REMARK 465     ASN H    91                                                      
REMARK 465     ASN H    92                                                      
REMARK 465     MET H    93                                                      
REMARK 465     GLU H    94                                                      
REMARK 465     ASN H    95                                                      
REMARK 465     ILE H    96                                                      
REMARK 465     ASN H    97                                                      
REMARK 465     GLY H    98                                                      
REMARK 465     GLU H    99                                                      
REMARK 465     GLU H   100                                                      
REMARK 465     VAL H   101                                                      
REMARK 465     ASP H   102                                                      
REMARK 465     GLU H   103                                                      
REMARK 465     GLU H   104                                                      
REMARK 465     ASP H   105                                                      
REMARK 465     ASP H   106                                                      
REMARK 465     GLU H   107                                                      
REMARK 465     ASP H   108                                                      
REMARK 465     MET J     1                                                      
REMARK 465     GLU J     2                                                      
REMARK 465     ARG J     3                                                      
REMARK 465     PRO J     4                                                      
REMARK 465     SER J     5                                                      
REMARK 465     PHE J     6                                                      
REMARK 465     LEU J     7                                                      
REMARK 465     ASP J     8                                                      
REMARK 465     GLN J     9                                                      
REMARK 465     GLU J    10                                                      
REMARK 465     PRO J    11                                                      
REMARK 465     PRO J    12                                                      
REMARK 465     ALA J    13                                                      
REMARK 465     GLY J    14                                                      
REMARK 465     TYR J    15                                                      
REMARK 465     VAL J    16                                                      
REMARK 465     PRO J    17                                                      
REMARK 465     GLY J    18                                                      
REMARK 465     ILE J    19                                                      
REMARK 465     GLY J    20                                                      
REMARK 465     ARG J    21                                                      
REMARK 465     GLY J    22                                                      
REMARK 465     ALA J    23                                                      
REMARK 465     THR J    24                                                      
REMARK 465     GLY J    25                                                      
REMARK 465     PHE J    26                                                      
REMARK 465     SER J    27                                                      
REMARK 465     THR J    28                                                      
REMARK 465     LYS J    29                                                      
REMARK 465     GLU J    30                                                      
REMARK 465     LYS J    31                                                      
REMARK 465     GLN J    32                                                      
REMARK 465     VAL J    33                                                      
REMARK 465     VAL J    34                                                      
REMARK 465     SER J    35                                                      
REMARK 465     ASN J    36                                                      
REMARK 465     ASP J    37                                                      
REMARK 465     ASP J    38                                                      
REMARK 465     LYS J    39                                                      
REMARK 465     GLY J    40                                                      
REMARK 465     ARG J    41                                                      
REMARK 465     ARG J    42                                                      
REMARK 465     ILE J    43                                                      
REMARK 465     PRO J    44                                                      
REMARK 465     LYS J    45                                                      
REMARK 465     ARG J    46                                                      
REMARK 465     TYR J    47                                                      
REMARK 465     ARG J    48                                                      
REMARK 465     GLU J    49                                                      
REMARK 465     ASN J    50                                                      
REMARK 465     LEU J    51                                                      
REMARK 465     ASN J    52                                                      
REMARK 465     ASN J    53                                                      
REMARK 465     HIS J    54                                                      
REMARK 465     LEU J    55                                                      
REMARK 465     GLN J    56                                                      
REMARK 465     SER J    57                                                      
REMARK 465     GLN J    58                                                      
REMARK 465     PRO J    59                                                      
REMARK 465     LYS J    60                                                      
REMARK 465     ASP J    61                                                      
REMARK 465     ASP J    62                                                      
REMARK 465     GLU J    63                                                      
REMARK 465     ASP J    64                                                      
REMARK 465     ASP J    65                                                      
REMARK 465     GLU J    66                                                      
REMARK 465     ALA J    67                                                      
REMARK 465     ALA J    68                                                      
REMARK 465     ASN J    69                                                      
REMARK 465     VAL J    70                                                      
REMARK 465     PHE J    71                                                      
REMARK 465     LYS J    72                                                      
REMARK 465     THR J    73                                                      
REMARK 465     LEU J    74                                                      
REMARK 465     GLU J    75                                                      
REMARK 465     LEU J    76                                                      
REMARK 465     LYS J    77                                                      
REMARK 465     LEU J    78                                                      
REMARK 465     ALA J    79                                                      
REMARK 465     GLN J    80                                                      
REMARK 465     LYS J    81                                                      
REMARK 465     LYS J    82                                                      
REMARK 465     LYS J    83                                                      
REMARK 465     LYS J    84                                                      
REMARK 465     ARG J    85                                                      
REMARK 465     ALA J    86                                                      
REMARK 465     ASN J    87                                                      
REMARK 465     GLU J    88                                                      
REMARK 465     LYS J    89                                                      
REMARK 465     ASP J    90                                                      
REMARK 465     ASP J    91                                                      
REMARK 465     ASP J    92                                                      
REMARK 465     ASN J    93                                                      
REMARK 465     SER J    94                                                      
REMARK 465     VAL J    95                                                      
REMARK 465     ASP J    96                                                      
REMARK 465     SER J    97                                                      
REMARK 465     SER J    98                                                      
REMARK 465     ASN J    99                                                      
REMARK 465     VAL J   100                                                      
REMARK 465     LYS J   101                                                      
REMARK 465     ARG J   102                                                      
REMARK 465     GLN J   103                                                      
REMARK 465     PHE J   104                                                      
REMARK 465     ALA J   105                                                      
REMARK 465     ASP J   106                                                      
REMARK 465     LEU J   107                                                      
REMARK 465     LYS J   108                                                      
REMARK 465     GLU J   109                                                      
REMARK 465     SER J   110                                                      
REMARK 465     LEU J   111                                                      
REMARK 465     ALA J   112                                                      
REMARK 465     ALA J   113                                                      
REMARK 465     VAL J   114                                                      
REMARK 465     THR J   115                                                      
REMARK 465     GLU J   116                                                      
REMARK 465     SER J   117                                                      
REMARK 465     GLU J   118                                                      
REMARK 465     TRP J   119                                                      
REMARK 465     MET J   120                                                      
REMARK 465     ASP J   121                                                      
REMARK 465     ILE J   122                                                      
REMARK 465     PRO J   123                                                      
REMARK 465     ASP J   124                                                      
REMARK 465     ALA J   125                                                      
REMARK 465     THR J   126                                                      
REMARK 465     ASP J   127                                                      
REMARK 465     PHE J   128                                                      
REMARK 465     THR J   129                                                      
REMARK 465     ARG J   130                                                      
REMARK 465     ARG J   131                                                      
REMARK 465     ASN J   132                                                      
REMARK 465     LYS J   133                                                      
REMARK 465     ARG J   134                                                      
REMARK 465     ASN J   135                                                      
REMARK 465     ARG J   136                                                      
REMARK 465     ILE J   137                                                      
REMARK 465     GLN J   138                                                      
REMARK 465     GLU J   139                                                      
REMARK 465     GLN J   140                                                      
REMARK 465     LEU J   141                                                      
REMARK 465     ASN J   142                                                      
REMARK 465     ARG J   143                                                      
REMARK 465     LYS J   144                                                      
REMARK 465     THR J   145                                                      
REMARK 465     TYR J   146                                                      
REMARK 465     ALA J   147                                                      
REMARK 465     ALA J   148                                                      
REMARK 465     PRO J   149                                                      
REMARK 465     ASP J   150                                                      
REMARK 465     SER J   151                                                      
REMARK 465     LEU J   152                                                      
REMARK 465     ILE J   153                                                      
REMARK 465     PRO J   154                                                      
REMARK 465     ASP J   415                                                      
REMARK 465     ILE J   416                                                      
REMARK 465     PRO J   417                                                      
REMARK 465     VAL J   418                                                      
REMARK 465     ASP J   419                                                      
REMARK 465     HIS J   527                                                      
REMARK 465     LYS J   528                                                      
REMARK 465     ILE J   529                                                      
REMARK 465     LYS J   544                                                      
REMARK 465     ASN J   545                                                      
REMARK 465     VAL J   881                                                      
REMARK 465     LYS J   882                                                      
REMARK 465     MET J   883                                                      
REMARK 465     GLN J   884                                                      
REMARK 465     TYR J   885                                                      
REMARK 465     LYS J   899                                                      
REMARK 465     MET D     1                                                      
REMARK 465     VAL D   142                                                      
REMARK 465     SER D   143                                                      
REMARK 465     MET F     1                                                      
REMARK 465     SER F     2                                                      
REMARK 465     SER F     3                                                      
REMARK 465     GLU F     4                                                      
REMARK 465     GLU F     5                                                      
REMARK 465     ASP F     6                                                      
REMARK 465     TYR F     7                                                      
REMARK 465     PHE F     8                                                      
REMARK 465     ASP F     9                                                      
REMARK 465     GLU F    10                                                      
REMARK 465     LEU F    11                                                      
REMARK 465     GLU F    12                                                      
REMARK 465     TYR F    13                                                      
REMARK 465     ASP F    14                                                      
REMARK 465     LEU F    15                                                      
REMARK 465     ALA F    16                                                      
REMARK 465     ASP F    17                                                      
REMARK 465     GLU F    18                                                      
REMARK 465     VAL F    19                                                      
REMARK 465     ASN F    20                                                      
REMARK 465     GLU F    21                                                      
REMARK 465     GLU F    22                                                      
REMARK 465     LYS F    23                                                      
REMARK 465     GLU F    24                                                      
REMARK 465     ASP F    25                                                      
REMARK 465     ILE F    26                                                      
REMARK 465     GLN F    27                                                      
REMARK 465     THR F    28                                                      
REMARK 465     LYS F    29                                                      
REMARK 465     LYS F    30                                                      
REMARK 465     LEU F    31                                                      
REMARK 465     THR F    32                                                      
REMARK 465     THR F    33                                                      
REMARK 465     VAL F    34                                                      
REMARK 465     ASN F    35                                                      
REMARK 465     CYS F    36                                                      
REMARK 465     GLN F    37                                                      
REMARK 465     THR F    38                                                      
REMARK 465     GLU F    39                                                      
REMARK 465     LYS F    40                                                      
REMARK 465     PHE F    41                                                      
REMARK 465     ASN F    42                                                      
REMARK 465     SER F   458                                                      
REMARK 465     LEU F   459                                                      
REMARK 465     GLY F   460                                                      
REMARK 465     HIS F   461                                                      
REMARK 465     ASN F   462                                                      
REMARK 465     THR F   463                                                      
REMARK 465     GLU F   464                                                      
REMARK 465     GLN F   465                                                      
REMARK 465     PRO F   466                                                      
REMARK 465     ASN F   467                                                      
REMARK 465     LEU F   468                                                      
REMARK 465     SER F   469                                                      
REMARK 465     PRO F   470                                                      
REMARK 465     GLU F   471                                                      
REMARK 465     MET F   472                                                      
REMARK 465     VAL F   473                                                      
REMARK 465     GLN F   474                                                      
REMARK 465     MET F   475                                                      
REMARK 465     HIS F   476                                                      
REMARK 465     LYS F   477                                                      
REMARK 465     LYS F   478                                                      
REMARK 465     GLN F   479                                                      
REMARK 465     HIS F   480                                                      
REMARK 465     THR F   481                                                      
REMARK 465     ASN F   482                                                      
REMARK 465     PRO F   483                                                      
REMARK 465     GLU F   484                                                      
REMARK 465     GLU F   485                                                      
REMARK 465     GLU F   486                                                      
REMARK 465     THR F   487                                                      
REMARK 465     ASN F   488                                                      
REMARK 465     TRP F   489                                                      
REMARK 465     PHE F   490                                                      
REMARK 465     SER F   491                                                      
REMARK 465     GLY F   492                                                      
REMARK 465     HIS F   493                                                      
REMARK 465     GLY F   494                                                      
REMARK 465     MET G     1                                                      
REMARK 465     PRO G     2                                                      
REMARK 465     PRO G     3                                                      
REMARK 465     ARG G     4                                                      
REMARK 465     ASN G     5                                                      
REMARK 465     THR G     6                                                      
REMARK 465     TYR G     7                                                      
REMARK 465     GLU G     8                                                      
REMARK 465     LYS G     9                                                      
REMARK 465     GLY G    10                                                      
REMARK 465     ASN G    11                                                      
REMARK 465     PRO G    12                                                      
REMARK 465     LYS G    13                                                      
REMARK 465     ARG G    14                                                      
REMARK 465     GLN G    15                                                      
REMARK 465     ASN G    16                                                      
REMARK 465     SER G    17                                                      
REMARK 465     PRO G    18                                                      
REMARK 465     TYR G    19                                                      
REMARK 465     TYR G    20                                                      
REMARK 465     LYS G    21                                                      
REMARK 465     PRO G    22                                                      
REMARK 465     SER G    23                                                      
REMARK 465     PHE G    24                                                      
REMARK 465     LEU G    25                                                      
REMARK 465     ARG G    26                                                      
REMARK 465     ARG G    27                                                      
REMARK 465     GLU G    28                                                      
REMARK 465     GLU G    29                                                      
REMARK 465     THR G    30                                                      
REMARK 465     THR G    31                                                      
REMARK 465     ASN G    32                                                      
REMARK 465     ASP G    33                                                      
REMARK 465     GLU G    34                                                      
REMARK 465     GLU G    35                                                      
REMARK 465     LYS G    36                                                      
REMARK 465     PHE G    37                                                      
REMARK 465     GLN G    38                                                      
REMARK 465     GLY G    39                                                      
REMARK 465     HIS G    40                                                      
REMARK 465     GLY G    41                                                      
REMARK 465     LEU G    42                                                      
REMARK 465     LYS G    43                                                      
REMARK 465     THR G    44                                                      
REMARK 465     GLU G    45                                                      
REMARK 465     LEU G    46                                                      
REMARK 465     HIS G    47                                                      
REMARK 465     SER G    48                                                      
REMARK 465     ALA G    49                                                      
REMARK 465     LEU G    50                                                      
REMARK 465     LYS G    51                                                      
REMARK 465     SER G    52                                                      
REMARK 465     SER G    53                                                      
REMARK 465     ASN G    54                                                      
REMARK 465     LEU G    55                                                      
REMARK 465     ASN G    56                                                      
REMARK 465     LEU G    57                                                      
REMARK 465     ILE G    58                                                      
REMARK 465     ARG G    59                                                      
REMARK 465     ARG G    60                                                      
REMARK 465     THR G    61                                                      
REMARK 465     TYR G    62                                                      
REMARK 465     GLN G    63                                                      
REMARK 465     THR G    64                                                      
REMARK 465     GLY G    65                                                      
REMARK 465     GLU G    66                                                      
REMARK 465     ASN G    67                                                      
REMARK 465     PRO G    68                                                      
REMARK 465     TYR G    69                                                      
REMARK 465     LEU G    70                                                      
REMARK 465     SER G    71                                                      
REMARK 465     ASP G    72                                                      
REMARK 465     PRO G    73                                                      
REMARK 465     HIS G    74                                                      
REMARK 465     ASP G    75                                                      
REMARK 465     ARG G    76                                                      
REMARK 465     GLY G    77                                                      
REMARK 465     SER G    78                                                      
REMARK 465     SER G    79                                                      
REMARK 465     SER G    80                                                      
REMARK 465     ARG G    81                                                      
REMARK 465     PHE G    82                                                      
REMARK 465     ASN G    83                                                      
REMARK 465     ARG G    84                                                      
REMARK 465     ARG G    85                                                      
REMARK 465     TYR G    86                                                      
REMARK 465     GLU G    87                                                      
REMARK 465     ARG G    88                                                      
REMARK 465     GLY G    89                                                      
REMARK 465     LEU G    90                                                      
REMARK 465     LYS G    91                                                      
REMARK 465     PHE G    92                                                      
REMARK 465     TYR G    93                                                      
REMARK 465     GLN G    94                                                      
REMARK 465     LYS G    95                                                      
REMARK 465     GLY G    96                                                      
REMARK 465     GLU G    97                                                      
REMARK 465     ILE G    98                                                      
REMARK 465     SER G    99                                                      
REMARK 465     LYS G   100                                                      
REMARK 465     ARG G   101                                                      
REMARK 465     ILE G   102                                                      
REMARK 465     ALA G   103                                                      
REMARK 465     GLN G   104                                                      
REMARK 465     GLU G   105                                                      
REMARK 465     ARG G   106                                                      
REMARK 465     THR G   107                                                      
REMARK 465     LEU G   108                                                      
REMARK 465     GLN G   109                                                      
REMARK 465     LYS G   110                                                      
REMARK 465     GLN G   111                                                      
REMARK 465     GLN G   112                                                      
REMARK 465     GLU G   113                                                      
REMARK 465     GLU G   114                                                      
REMARK 465     GLU G   115                                                      
REMARK 465     GLU G   116                                                      
REMARK 465     LEU G   117                                                      
REMARK 465     LYS G   118                                                      
REMARK 465     ARG G   119                                                      
REMARK 465     LYS G   120                                                      
REMARK 465     LEU G   121                                                      
REMARK 465     LYS G   122                                                      
REMARK 465     GLN G   123                                                      
REMARK 465     GLU G   124                                                      
REMARK 465     GLU G   125                                                      
REMARK 465     ASP G   126                                                      
REMARK 465     GLU G   127                                                      
REMARK 465     LYS G   128                                                      
REMARK 465     ASP G   129                                                      
REMARK 465     LYS G   130                                                      
REMARK 465     ARG G   131                                                      
REMARK 465     LYS G   132                                                      
REMARK 465     LEU G   133                                                      
REMARK 465     ILE G   134                                                      
REMARK 465     GLU G   135                                                      
REMARK 465     SER G   136                                                      
REMARK 465     GLY G   137                                                      
REMARK 465     ASP G   138                                                      
REMARK 465     LEU G   139                                                      
REMARK 465     PRO G   140                                                      
REMARK 465     ASN G   141                                                      
REMARK 465     LEU G   142                                                      
REMARK 465     GLU G   143                                                      
REMARK 465     LEU G   144                                                      
REMARK 465     HIS G   145                                                      
REMARK 465     GLU G   146                                                      
REMARK 465     ASP G   147                                                      
REMARK 465     LYS G   148                                                      
REMARK 465     PHE G   149                                                      
REMARK 465     GLN G   468                                                      
REMARK 465     THR G   469                                                      
REMARK 465     MET K     1                                                      
REMARK 465     SER K     2                                                      
REMARK 465     MET B     1                                                      
REMARK 465     THR B     2                                                      
REMARK 465     GLU B     3                                                      
REMARK 465     HIS B     4                                                      
REMARK 465     GLU B     5                                                      
REMARK 465     THR B     6                                                      
REMARK 465     LYS B     7                                                      
REMARK 465     ASP B     8                                                      
REMARK 465     LYS B     9                                                      
REMARK 465     ALA B    10                                                      
REMARK 465     LYS B    11                                                      
REMARK 465     LYS B    12                                                      
REMARK 465     ILE B    13                                                      
REMARK 465     ARG B    14                                                      
REMARK 465     GLU B    15                                                      
REMARK 465     ILE B    16                                                      
REMARK 465     TYR B    17                                                      
REMARK 465     ARG B    18                                                      
REMARK 465     TYR B    19                                                      
REMARK 465     ASP B    20                                                      
REMARK 465     GLU B    21                                                      
REMARK 465     MET B    22                                                      
REMARK 465     SER B    23                                                      
REMARK 465     ASN B    24                                                      
REMARK 465     LYS B    25                                                      
REMARK 465     VAL B    26                                                      
REMARK 465     LEU B    27                                                      
REMARK 465     LYS B    28                                                      
REMARK 465     VAL B    29                                                      
REMARK 465     ASP B    30                                                      
REMARK 465     LYS B    31                                                      
REMARK 465     ARG B    32                                                      
REMARK 465     PHE B    33                                                      
REMARK 465     MET B    34                                                      
REMARK 465     ASN B    35                                                      
REMARK 465     THR B    36                                                      
REMARK 465     SER B    37                                                      
REMARK 465     GLN B    38                                                      
REMARK 465     ASN B    39                                                      
REMARK 465     PRO B    40                                                      
REMARK 465     GLN B    41                                                      
REMARK 465     ARG B    42                                                      
REMARK 465     ASP B    43                                                      
REMARK 465     ALA B    44                                                      
REMARK 465     GLU B    45                                                      
REMARK 465     ILE B    46                                                      
REMARK 465     SER B    47                                                      
REMARK 465     GLN B    48                                                      
REMARK 465     PRO B    49                                                      
REMARK 465     LYS B    50                                                      
REMARK 465     SER B    51                                                      
REMARK 465     MET B    52                                                      
REMARK 465     SER B    53                                                      
REMARK 465     GLY B    54                                                      
REMARK 465     ARG B    55                                                      
REMARK 465     ILE B    56                                                      
REMARK 465     SER B    57                                                      
REMARK 465     ALA B    58                                                      
REMARK 465     LYS B    59                                                      
REMARK 465     ASP B    60                                                      
REMARK 465     MET B    61                                                      
REMARK 465     GLY B    62                                                      
REMARK 465     GLN B    63                                                      
REMARK 465     GLY B    64                                                      
REMARK 465     LEU B    65                                                      
REMARK 465     CYS B    66                                                      
REMARK 465     ASN B    67                                                      
REMARK 465     ASN B    68                                                      
REMARK 465     ILE B    69                                                      
REMARK 465     ASN B    70                                                      
REMARK 465     LYS B    71                                                      
REMARK 465     GLY B    72                                                      
REMARK 465     LEU B    73                                                      
REMARK 465     LYS B    74                                                      
REMARK 465     GLU B    75                                                      
REMARK 465     ASN B    76                                                      
REMARK 465     ASP B    77                                                      
REMARK 465     VAL B    78                                                      
REMARK 465     ALA B    79                                                      
REMARK 465     VAL B    80                                                      
REMARK 465     GLU B    81                                                      
REMARK 465     LYS B    82                                                      
REMARK 465     THR B    83                                                      
REMARK 465     GLY B    84                                                      
REMARK 465     LYS B    85                                                      
REMARK 465     SER B    86                                                      
REMARK 465     ALA B    87                                                      
REMARK 465     SER B    88                                                      
REMARK 465     LEU B    89                                                      
REMARK 465     LYS B    90                                                      
REMARK 465     LYS B    91                                                      
REMARK 465     ILE B    92                                                      
REMARK 465     GLN B    93                                                      
REMARK 465     GLN B    94                                                      
REMARK 465     HIS B    95                                                      
REMARK 465     ASN B    96                                                      
REMARK 465     THR B    97                                                      
REMARK 465     ILE B    98                                                      
REMARK 465     LEU B    99                                                      
REMARK 465     ASN B   100                                                      
REMARK 465     SER B   101                                                      
REMARK 465     SER B   102                                                      
REMARK 465     SER B   103                                                      
REMARK 465     ASP B   104                                                      
REMARK 465     PHE B   105                                                      
REMARK 465     ARG B   106                                                      
REMARK 465     LEU B   107                                                      
REMARK 465     HIS B   108                                                      
REMARK 465     TYR B   109                                                      
REMARK 465     TYR B   110                                                      
REMARK 465     PRO B   111                                                      
REMARK 465     LYS B   112                                                      
REMARK 465     ASP B   113                                                      
REMARK 465     PRO B   114                                                      
REMARK 465     SER B   115                                                      
REMARK 465     ASN B   116                                                      
REMARK 465     VAL B   117                                                      
REMARK 465     GLU B   118                                                      
REMARK 465     THR B   119                                                      
REMARK 465     TYR B   120                                                      
REMARK 465     GLU B   121                                                      
REMARK 465     GLN B   122                                                      
REMARK 465     ILE B   123                                                      
REMARK 465     LEU B   124                                                      
REMARK 465     GLN B   125                                                      
REMARK 465     TRP B   126                                                      
REMARK 465     VAL B   127                                                      
REMARK 465     THR B   128                                                      
REMARK 465     GLU B   129                                                      
REMARK 465     VAL B   130                                                      
REMARK 465     LEU B   131                                                      
REMARK 465     GLY B   132                                                      
REMARK 465     ASN B   133                                                      
REMARK 465     ASP B   134                                                      
REMARK 465     ILE B   135                                                      
REMARK 465     PRO B   136                                                      
REMARK 465     HIS B   137                                                      
REMARK 465     ASP B   138                                                      
REMARK 465     LEU B   139                                                      
REMARK 465     ILE B   140                                                      
REMARK 465     ILE B   141                                                      
REMARK 465     GLY B   142                                                      
REMARK 465     THR B   143                                                      
REMARK 465     ALA B   144                                                      
REMARK 465     ASP B   145                                                      
REMARK 465     ILE B   146                                                      
REMARK 465     PHE B   147                                                      
REMARK 465     ILE B   148                                                      
REMARK 465     ARG B   149                                                      
REMARK 465     GLN B   150                                                      
REMARK 465     LEU B   151                                                      
REMARK 465     LYS B   152                                                      
REMARK 465     GLU B   153                                                      
REMARK 465     ASN B   154                                                      
REMARK 465     GLU B   155                                                      
REMARK 465     GLU B   156                                                      
REMARK 465     ASN B   157                                                      
REMARK 465     GLU B   158                                                      
REMARK 465     ASP B   159                                                      
REMARK 465     GLY B   160                                                      
REMARK 465     ASN B   161                                                      
REMARK 465     ILE B   162                                                      
REMARK 465     GLU B   163                                                      
REMARK 465     GLU B   164                                                      
REMARK 465     ARG B   165                                                      
REMARK 465     LYS B   166                                                      
REMARK 465     GLU B   167                                                      
REMARK 465     LYS B   168                                                      
REMARK 465     ILE B   169                                                      
REMARK 465     GLN B   170                                                      
REMARK 465     HIS B   171                                                      
REMARK 465     GLU B   172                                                      
REMARK 465     LEU B   173                                                      
REMARK 465     GLY B   174                                                      
REMARK 465     ILE B   175                                                      
REMARK 465     ASN B   176                                                      
REMARK 465     ILE B   177                                                      
REMARK 465     ASP B   178                                                      
REMARK 465     SER B   179                                                      
REMARK 465     LEU B   180                                                      
REMARK 465     LYS B   181                                                      
REMARK 465     PHE B   182                                                      
REMARK 465     ASN B   183                                                      
REMARK 465     GLU B   184                                                      
REMARK 465     LEU B   185                                                      
REMARK 465     VAL B   186                                                      
REMARK 465     LYS B   187                                                      
REMARK 465     LEU B   188                                                      
REMARK 465     MET B   189                                                      
REMARK 465     LYS B   190                                                      
REMARK 465     ASN B   191                                                      
REMARK 465     ILE B   192                                                      
REMARK 465     THR B   193                                                      
REMARK 465     ASP B   194                                                      
REMARK 465     TYR B   195                                                      
REMARK 465     GLU B   196                                                      
REMARK 465     THR B   197                                                      
REMARK 465     HIS B   198                                                      
REMARK 465     PRO B   199                                                      
REMARK 465     ASP B   200                                                      
REMARK 465     ASN B   201                                                      
REMARK 465     SER B   202                                                      
REMARK 465     ASN B   203                                                      
REMARK 465     LYS B   204                                                      
REMARK 465     GLN B   205                                                      
REMARK 465     ALA B   206                                                      
REMARK 465     VAL B   207                                                      
REMARK 465     ALA B   208                                                      
REMARK 465     ILE B   209                                                      
REMARK 465     LEU B   210                                                      
REMARK 465     ALA B   211                                                      
REMARK 465     ASP B   212                                                      
REMARK 465     ASP B   213                                                      
REMARK 465     GLU B   214                                                      
REMARK 465     LYS B   215                                                      
REMARK 465     SER B   216                                                      
REMARK 465     ASP B   217                                                      
REMARK 465     GLU B   218                                                      
REMARK 465     GLU B   219                                                      
REMARK 465     GLU B   220                                                      
REMARK 465     VAL B   221                                                      
REMARK 465     THR B   222                                                      
REMARK 465     GLU B   223                                                      
REMARK 465     MET B   224                                                      
REMARK 465     SER B   225                                                      
REMARK 465     ASN B   226                                                      
REMARK 465     ASN B   227                                                      
REMARK 465     ALA B   228                                                      
REMARK 465     ASN B   229                                                      
REMARK 465     VAL B   230                                                      
REMARK 465     LEU B   231                                                      
REMARK 465     GLY B   232                                                      
REMARK 465     GLY B   233                                                      
REMARK 465     GLU B   234                                                      
REMARK 465     ILE B   235                                                      
REMARK 465     ASN B   236                                                      
REMARK 465     ASP B   237                                                      
REMARK 465     ASN B   238                                                      
REMARK 465     GLU B   239                                                      
REMARK 465     ASP B   240                                                      
REMARK 465     ASP B   241                                                      
REMARK 465     ASP B   242                                                      
REMARK 465     GLU B   243                                                      
REMARK 465     GLU B   244                                                      
REMARK 465     TYR B   245                                                      
REMARK 465     ASP B   246                                                      
REMARK 465     TYR B   247                                                      
REMARK 465     ASN B   248                                                      
REMARK 465     ASP B   249                                                      
REMARK 465     VAL B   250                                                      
REMARK 465     GLU B   251                                                      
REMARK 465     VAL B   252                                                      
REMARK 465     ASN B   253                                                      
REMARK 465     SER B   254                                                      
REMARK 465     LYS B   255                                                      
REMARK 465     LYS B   256                                                      
REMARK 465     LYS B   257                                                      
REMARK 465     ASN B   258                                                      
REMARK 465     LYS B   259                                                      
REMARK 465     ARG B   260                                                      
REMARK 465     ALA B   261                                                      
REMARK 465     LEU B   262                                                      
REMARK 465     PRO B   263                                                      
REMARK 465     ASN B   264                                                      
REMARK 465     ILE B   265                                                      
REMARK 465     GLU B   266                                                      
REMARK 465     ASN B   267                                                      
REMARK 465     ASP B   268                                                      
REMARK 465     ILE B   269                                                      
REMARK 465     ILE B   270                                                      
REMARK 465     LYS B   271                                                      
REMARK 465     LEU B   272                                                      
REMARK 465     SER B   273                                                      
REMARK 465     ASP B   274                                                      
REMARK 465     SER B   275                                                      
REMARK 465     LYS B   276                                                      
REMARK 465     THR B   277                                                      
REMARK 465     SER B   278                                                      
REMARK 465     ASN B   279                                                      
REMARK 465     ILE B   280                                                      
REMARK 465     GLU B   281                                                      
REMARK 465     SER B   282                                                      
REMARK 465     VAL B   283                                                      
REMARK 465     PRO B   284                                                      
REMARK 465     ILE B   285                                                      
REMARK 465     TYR B   286                                                      
REMARK 465     SER B   287                                                      
REMARK 465     ILE B   288                                                      
REMARK 465     ASP B   289                                                      
REMARK 465     GLU B   290                                                      
REMARK 465     PHE B   291                                                      
REMARK 465     PHE B   292                                                      
REMARK 465     LEU B   293                                                      
REMARK 465     GLN B   294                                                      
REMARK 465     ARG B   295                                                      
REMARK 465     LYS B   296                                                      
REMARK 465     LEU B   297                                                      
REMARK 465     ARG B   298                                                      
REMARK 465     SER B   299                                                      
REMARK 465     GLU B   300                                                      
REMARK 465     LEU B   301                                                      
REMARK 465     GLY B   302                                                      
REMARK 465     TYR B   303                                                      
REMARK 465     LYS B   304                                                      
REMARK 465     ASP B   305                                                      
REMARK 465     THR B   306                                                      
REMARK 465     SER B   307                                                      
REMARK 465     VAL B   308                                                      
REMARK 465     ILE B   309                                                      
REMARK 465     GLN B   310                                                      
REMARK 465     ASP B   311                                                      
REMARK 465     LEU B   312                                                      
REMARK 465     SER B   313                                                      
REMARK 465     GLU B   314                                                      
REMARK 465     LYS B   315                                                      
REMARK 465     ILE B   316                                                      
REMARK 465     LEU B   317                                                      
REMARK 465     ASN B   318                                                      
REMARK 465     ASP B   319                                                      
REMARK 465     ILE B   320                                                      
REMARK 465     GLU B   321                                                      
REMARK 465     THR B   322                                                      
REMARK 465     LEU B   323                                                      
REMARK 465     GLU B   324                                                      
REMARK 465     HIS B   325                                                      
REMARK 465     ASN B   326                                                      
REMARK 465     PRO B   327                                                      
REMARK 465     VAL B   328                                                      
REMARK 465     ALA B   329                                                      
REMARK 465     LEU B   330                                                      
REMARK 465     GLU B   331                                                      
REMARK 465     GLN B   332                                                      
REMARK 465     LYS B   333                                                      
REMARK 465     LEU B   334                                                      
REMARK 465     VAL B   335                                                      
REMARK 465     ASP B   336                                                      
REMARK 465     LEU B   337                                                      
REMARK 465     LEU B   338                                                      
REMARK 465     LYS B   339                                                      
REMARK 465     PHE B   340                                                      
REMARK 465     GLU B   341                                                      
REMARK 465     ASN B   342                                                      
REMARK 465     ILE B   343                                                      
REMARK 465     SER B   344                                                      
REMARK 465     LEU B   345                                                      
REMARK 465     ALA B   346                                                      
REMARK 465     GLU B   347                                                      
REMARK 465     PHE B   348                                                      
REMARK 465     ILE B   349                                                      
REMARK 465     LEU B   350                                                      
REMARK 465     LYS B   351                                                      
REMARK 465     ASN B   352                                                      
REMARK 465     ARG B   353                                                      
REMARK 465     SER B   354                                                      
REMARK 465     THR B   355                                                      
REMARK 465     ILE B   356                                                      
REMARK 465     PHE B   357                                                      
REMARK 465     TRP B   358                                                      
REMARK 465     GLY B   359                                                      
REMARK 465     ILE B   360                                                      
REMARK 465     ARG B   361                                                      
REMARK 465     LEU B   362                                                      
REMARK 465     PHE B   434                                                      
REMARK 465     ASP B   435                                                      
REMARK 465     GLU B   436                                                      
REMARK 465     SER B   437                                                      
REMARK 465     SER B   438                                                      
REMARK 465     LYS B   439                                                      
REMARK 465     LEU B   440                                                      
REMARK 465     MET B   441                                                      
REMARK 465     THR B   442                                                      
REMARK 465     VAL B   443                                                      
REMARK 465     THR B   444                                                      
REMARK 465     LYS B   445                                                      
REMARK 465     VAL B   446                                                      
REMARK 465     SER B   447                                                      
REMARK 465     LEU B   448                                                      
REMARK 465     PRO B   449                                                      
REMARK 465     GLU B   450                                                      
REMARK 465     GLY B   451                                                      
REMARK 465     SER B   452                                                      
REMARK 465     PHE B   453                                                      
REMARK 465     LYS B   454                                                      
REMARK 465     ARG B   455                                                      
REMARK 465     VAL B   456                                                      
REMARK 465     LYS B   457                                                      
REMARK 465     PRO B   458                                                      
REMARK 465     GLN B   459                                                      
REMARK 465     TYR B   460                                                      
REMARK 465     ASP B   461                                                      
REMARK 465     GLU B   462                                                      
REMARK 465     ILE B   463                                                      
REMARK 465     HIS B   464                                                      
REMARK 465     ILE B   465                                                      
REMARK 465     PRO B   466                                                      
REMARK 465     ALA B   467                                                      
REMARK 465     PRO B   468                                                      
REMARK 465     SER B   469                                                      
REMARK 465     LYS B   470                                                      
REMARK 465     PRO B   471                                                      
REMARK 465     VAL B   472                                                      
REMARK 465     ILE B   473                                                      
REMARK 465     ASP B   474                                                      
REMARK 465     TYR B   475                                                      
REMARK 465     GLU B   476                                                      
REMARK 465     LEU B   477                                                      
REMARK 465     LYS B   478                                                      
REMARK 465     GLU B   479                                                      
REMARK 465     ILE B   480                                                      
REMARK 465     THR B   481                                                      
REMARK 465     SER B   482                                                      
REMARK 465     LEU B   483                                                      
REMARK 465     PRO B   484                                                      
REMARK 465     ASP B   485                                                      
REMARK 465     TRP B   486                                                      
REMARK 465     CYS B   487                                                      
REMARK 465     GLN B   488                                                      
REMARK 465     GLU B   489                                                      
REMARK 465     ALA B   490                                                      
REMARK 465     PHE B   491                                                      
REMARK 465     PRO B   492                                                      
REMARK 465     SER B   493                                                      
REMARK 465     SER B   494                                                      
REMARK 465     GLU B   495                                                      
REMARK 465     THR B   496                                                      
REMARK 465     THR B   497                                                      
REMARK 465     SER B   498                                                      
REMARK 465     LEU B   499                                                      
REMARK 465     ASN B   500                                                      
REMARK 465     PRO B   501                                                      
REMARK 465     ILE B   502                                                      
REMARK 465     GLN B   503                                                      
REMARK 465     SER B   504                                                      
REMARK 465     LYS B   505                                                      
REMARK 465     VAL B   506                                                      
REMARK 465     PHE B   507                                                      
REMARK 465     HIS B   508                                                      
REMARK 465     ALA B   509                                                      
REMARK 465     ALA B   510                                                      
REMARK 465     PHE B   511                                                      
REMARK 465     GLU B   512                                                      
REMARK 465     GLY B   513                                                      
REMARK 465     ASP B   514                                                      
REMARK 465     SER B   515                                                      
REMARK 465     ASN B   516                                                      
REMARK 465     MET B   517                                                      
REMARK 465     LEU B   518                                                      
REMARK 465     ILE B   519                                                      
REMARK 465     CYS B   520                                                      
REMARK 465     ALA B   521                                                      
REMARK 465     PRO B   522                                                      
REMARK 465     THR B   523                                                      
REMARK 465     GLY B   524                                                      
REMARK 465     SER B   525                                                      
REMARK 465     GLY B   526                                                      
REMARK 465     LYS B   527                                                      
REMARK 465     THR B   528                                                      
REMARK 465     ASN B   529                                                      
REMARK 465     ILE B   530                                                      
REMARK 465     ALA B   531                                                      
REMARK 465     LEU B   532                                                      
REMARK 465     LEU B   533                                                      
REMARK 465     THR B   534                                                      
REMARK 465     VAL B   535                                                      
REMARK 465     LEU B   536                                                      
REMARK 465     LYS B   537                                                      
REMARK 465     ALA B   538                                                      
REMARK 465     LEU B   539                                                      
REMARK 465     SER B   540                                                      
REMARK 465     HIS B   541                                                      
REMARK 465     HIS B   542                                                      
REMARK 465     TYR B   543                                                      
REMARK 465     ASN B   544                                                      
REMARK 465     PRO B   545                                                      
REMARK 465     LYS B   546                                                      
REMARK 465     THR B   547                                                      
REMARK 465     LYS B   548                                                      
REMARK 465     LYS B   549                                                      
REMARK 465     LEU B   550                                                      
REMARK 465     ASN B   551                                                      
REMARK 465     LEU B   552                                                      
REMARK 465     SER B   553                                                      
REMARK 465     ALA B   554                                                      
REMARK 465     PHE B   555                                                      
REMARK 465     LYS B   556                                                      
REMARK 465     ILE B   557                                                      
REMARK 465     VAL B   558                                                      
REMARK 465     TYR B   559                                                      
REMARK 465     ILE B   560                                                      
REMARK 465     ALA B   561                                                      
REMARK 465     PRO B   562                                                      
REMARK 465     LEU B   563                                                      
REMARK 465     LYS B   564                                                      
REMARK 465     ALA B   565                                                      
REMARK 465     LEU B   566                                                      
REMARK 465     VAL B   567                                                      
REMARK 465     GLN B   568                                                      
REMARK 465     GLU B   569                                                      
REMARK 465     GLN B   570                                                      
REMARK 465     VAL B   571                                                      
REMARK 465     ARG B   572                                                      
REMARK 465     GLU B   573                                                      
REMARK 465     PHE B   574                                                      
REMARK 465     GLN B   575                                                      
REMARK 465     ARG B   576                                                      
REMARK 465     ARG B   577                                                      
REMARK 465     LEU B   578                                                      
REMARK 465     ALA B   579                                                      
REMARK 465     PHE B   580                                                      
REMARK 465     LEU B   581                                                      
REMARK 465     GLY B   582                                                      
REMARK 465     ILE B   583                                                      
REMARK 465     LYS B   584                                                      
REMARK 465     VAL B   585                                                      
REMARK 465     ALA B   586                                                      
REMARK 465     GLU B   587                                                      
REMARK 465     LEU B   588                                                      
REMARK 465     THR B   589                                                      
REMARK 465     GLY B   590                                                      
REMARK 465     ASP B   591                                                      
REMARK 465     SER B   592                                                      
REMARK 465     ARG B   593                                                      
REMARK 465     LEU B   594                                                      
REMARK 465     SER B   595                                                      
REMARK 465     ARG B   596                                                      
REMARK 465     LYS B   597                                                      
REMARK 465     GLN B   598                                                      
REMARK 465     ILE B   599                                                      
REMARK 465     ASP B   600                                                      
REMARK 465     GLU B   601                                                      
REMARK 465     THR B   602                                                      
REMARK 465     GLN B   603                                                      
REMARK 465     VAL B   604                                                      
REMARK 465     LEU B   605                                                      
REMARK 465     VAL B   606                                                      
REMARK 465     SER B   607                                                      
REMARK 465     THR B   608                                                      
REMARK 465     PRO B   609                                                      
REMARK 465     GLU B   610                                                      
REMARK 465     LYS B   611                                                      
REMARK 465     TRP B   612                                                      
REMARK 465     ASP B   613                                                      
REMARK 465     ILE B   614                                                      
REMARK 465     THR B   615                                                      
REMARK 465     THR B   616                                                      
REMARK 465     ARG B   617                                                      
REMARK 465     ASN B   618                                                      
REMARK 465     SER B   619                                                      
REMARK 465     ASN B   620                                                      
REMARK 465     ASN B   621                                                      
REMARK 465     LEU B   622                                                      
REMARK 465     ALA B   623                                                      
REMARK 465     ILE B   624                                                      
REMARK 465     VAL B   625                                                      
REMARK 465     GLU B   626                                                      
REMARK 465     LEU B   627                                                      
REMARK 465     VAL B   628                                                      
REMARK 465     ARG B   629                                                      
REMARK 465     LEU B   630                                                      
REMARK 465     LEU B   631                                                      
REMARK 465     ILE B   632                                                      
REMARK 465     ILE B   633                                                      
REMARK 465     ASP B   634                                                      
REMARK 465     GLU B   635                                                      
REMARK 465     ILE B   636                                                      
REMARK 465     HIS B   637                                                      
REMARK 465     LEU B   638                                                      
REMARK 465     LEU B   639                                                      
REMARK 465     HIS B   640                                                      
REMARK 465     ASP B   641                                                      
REMARK 465     ASP B   642                                                      
REMARK 465     ARG B   643                                                      
REMARK 465     GLY B   644                                                      
REMARK 465     PRO B   645                                                      
REMARK 465     VAL B   646                                                      
REMARK 465     LEU B   647                                                      
REMARK 465     GLU B   648                                                      
REMARK 465     SER B   649                                                      
REMARK 465     ILE B   650                                                      
REMARK 465     VAL B   651                                                      
REMARK 465     ALA B   652                                                      
REMARK 465     ARG B   653                                                      
REMARK 465     THR B   654                                                      
REMARK 465     PHE B   655                                                      
REMARK 465     TRP B   656                                                      
REMARK 465     ALA B   657                                                      
REMARK 465     SER B   658                                                      
REMARK 465     LYS B   659                                                      
REMARK 465     TYR B   660                                                      
REMARK 465     GLY B   661                                                      
REMARK 465     GLN B   662                                                      
REMARK 465     GLU B   663                                                      
REMARK 465     TYR B   664                                                      
REMARK 465     PRO B   665                                                      
REMARK 465     ARG B   666                                                      
REMARK 465     ILE B   667                                                      
REMARK 465     ILE B   668                                                      
REMARK 465     GLY B   669                                                      
REMARK 465     LEU B   670                                                      
REMARK 465     SER B   671                                                      
REMARK 465     ALA B   672                                                      
REMARK 465     THR B   673                                                      
REMARK 465     LEU B   674                                                      
REMARK 465     PRO B   675                                                      
REMARK 465     ASN B   676                                                      
REMARK 465     TYR B   677                                                      
REMARK 465     GLU B   678                                                      
REMARK 465     ASP B   679                                                      
REMARK 465     VAL B   680                                                      
REMARK 465     GLY B   681                                                      
REMARK 465     ARG B   682                                                      
REMARK 465     PHE B   683                                                      
REMARK 465     LEU B   684                                                      
REMARK 465     ARG B   685                                                      
REMARK 465     VAL B   686                                                      
REMARK 465     PRO B   687                                                      
REMARK 465     LYS B   688                                                      
REMARK 465     GLU B   689                                                      
REMARK 465     GLY B   690                                                      
REMARK 465     LEU B   691                                                      
REMARK 465     PHE B   692                                                      
REMARK 465     TYR B   693                                                      
REMARK 465     PHE B   694                                                      
REMARK 465     ASP B   695                                                      
REMARK 465     SER B   696                                                      
REMARK 465     SER B   697                                                      
REMARK 465     PHE B   698                                                      
REMARK 465     ARG B   699                                                      
REMARK 465     PRO B   700                                                      
REMARK 465     CYS B   701                                                      
REMARK 465     PRO B   702                                                      
REMARK 465     LEU B   703                                                      
REMARK 465     SER B   704                                                      
REMARK 465     GLN B   705                                                      
REMARK 465     GLN B   706                                                      
REMARK 465     PHE B   707                                                      
REMARK 465     CYS B   708                                                      
REMARK 465     GLY B   709                                                      
REMARK 465     ILE B   710                                                      
REMARK 465     LYS B   711                                                      
REMARK 465     GLU B   712                                                      
REMARK 465     ARG B   713                                                      
REMARK 465     ASN B   714                                                      
REMARK 465     SER B   715                                                      
REMARK 465     LEU B   716                                                      
REMARK 465     LYS B   717                                                      
REMARK 465     LYS B   718                                                      
REMARK 465     LEU B   719                                                      
REMARK 465     LYS B   720                                                      
REMARK 465     ALA B   721                                                      
REMARK 465     MET B   722                                                      
REMARK 465     ASN B   723                                                      
REMARK 465     ASP B   724                                                      
REMARK 465     ALA B   725                                                      
REMARK 465     CYS B   726                                                      
REMARK 465     TYR B   727                                                      
REMARK 465     GLU B   728                                                      
REMARK 465     LYS B   729                                                      
REMARK 465     VAL B   730                                                      
REMARK 465     LEU B   731                                                      
REMARK 465     GLU B   732                                                      
REMARK 465     SER B   733                                                      
REMARK 465     ILE B   734                                                      
REMARK 465     ASN B   735                                                      
REMARK 465     GLU B   736                                                      
REMARK 465     GLY B   737                                                      
REMARK 465     ASN B   738                                                      
REMARK 465     GLN B   739                                                      
REMARK 465     ILE B   740                                                      
REMARK 465     ILE B   741                                                      
REMARK 465     VAL B   742                                                      
REMARK 465     PHE B   743                                                      
REMARK 465     VAL B   744                                                      
REMARK 465     HIS B   745                                                      
REMARK 465     SER B   746                                                      
REMARK 465     ARG B   747                                                      
REMARK 465     LYS B   748                                                      
REMARK 465     GLU B   749                                                      
REMARK 465     THR B   750                                                      
REMARK 465     SER B   751                                                      
REMARK 465     ARG B   752                                                      
REMARK 465     THR B   753                                                      
REMARK 465     ALA B   754                                                      
REMARK 465     THR B   755                                                      
REMARK 465     TRP B   756                                                      
REMARK 465     LEU B   757                                                      
REMARK 465     LYS B   758                                                      
REMARK 465     ASN B   759                                                      
REMARK 465     LYS B   760                                                      
REMARK 465     PHE B   761                                                      
REMARK 465     ALA B   762                                                      
REMARK 465     GLU B   763                                                      
REMARK 465     GLU B   764                                                      
REMARK 465     ASN B   765                                                      
REMARK 465     ILE B   766                                                      
REMARK 465     THR B   767                                                      
REMARK 465     HIS B   768                                                      
REMARK 465     LYS B   769                                                      
REMARK 465     LEU B   770                                                      
REMARK 465     THR B   771                                                      
REMARK 465     LYS B   772                                                      
REMARK 465     ASN B   773                                                      
REMARK 465     ASP B   774                                                      
REMARK 465     ALA B   775                                                      
REMARK 465     GLY B   776                                                      
REMARK 465     SER B   777                                                      
REMARK 465     LYS B   778                                                      
REMARK 465     GLN B   779                                                      
REMARK 465     ILE B   780                                                      
REMARK 465     LEU B   781                                                      
REMARK 465     LYS B   782                                                      
REMARK 465     THR B   783                                                      
REMARK 465     GLU B   784                                                      
REMARK 465     ALA B   785                                                      
REMARK 465     ALA B   786                                                      
REMARK 465     ASN B   787                                                      
REMARK 465     VAL B   788                                                      
REMARK 465     LEU B   789                                                      
REMARK 465     ASP B   790                                                      
REMARK 465     PRO B   791                                                      
REMARK 465     SER B   792                                                      
REMARK 465     LEU B   793                                                      
REMARK 465     ARG B   794                                                      
REMARK 465     LYS B   795                                                      
REMARK 465     LEU B   796                                                      
REMARK 465     ILE B   797                                                      
REMARK 465     GLU B   798                                                      
REMARK 465     SER B   799                                                      
REMARK 465     GLY B   800                                                      
REMARK 465     ILE B   801                                                      
REMARK 465     GLY B   802                                                      
REMARK 465     THR B   803                                                      
REMARK 465     HIS B   804                                                      
REMARK 465     HIS B   805                                                      
REMARK 465     ALA B   806                                                      
REMARK 465     GLY B   807                                                      
REMARK 465     LEU B   808                                                      
REMARK 465     THR B   809                                                      
REMARK 465     ARG B   810                                                      
REMARK 465     SER B   811                                                      
REMARK 465     ASP B   812                                                      
REMARK 465     ARG B   813                                                      
REMARK 465     SER B   814                                                      
REMARK 465     LEU B   815                                                      
REMARK 465     SER B   816                                                      
REMARK 465     GLU B   817                                                      
REMARK 465     ASP B   818                                                      
REMARK 465     LEU B   819                                                      
REMARK 465     PHE B   820                                                      
REMARK 465     ALA B   821                                                      
REMARK 465     ASP B   822                                                      
REMARK 465     GLY B   823                                                      
REMARK 465     LEU B   824                                                      
REMARK 465     LEU B   825                                                      
REMARK 465     GLN B   826                                                      
REMARK 465     VAL B   827                                                      
REMARK 465     LEU B   828                                                      
REMARK 465     VAL B   829                                                      
REMARK 465     CYS B   830                                                      
REMARK 465     THR B   831                                                      
REMARK 465     ALA B   832                                                      
REMARK 465     THR B   833                                                      
REMARK 465     LEU B   834                                                      
REMARK 465     ALA B   835                                                      
REMARK 465     TRP B   836                                                      
REMARK 465     GLY B   837                                                      
REMARK 465     VAL B   838                                                      
REMARK 465     ASN B   839                                                      
REMARK 465     LEU B   840                                                      
REMARK 465     PRO B   841                                                      
REMARK 465     ALA B   842                                                      
REMARK 465     HIS B   843                                                      
REMARK 465     THR B   844                                                      
REMARK 465     VAL B   845                                                      
REMARK 465     ILE B   846                                                      
REMARK 465     ILE B   847                                                      
REMARK 465     LYS B   848                                                      
REMARK 465     GLY B   849                                                      
REMARK 465     THR B   850                                                      
REMARK 465     ASP B   851                                                      
REMARK 465     VAL B   852                                                      
REMARK 465     TYR B   853                                                      
REMARK 465     SER B   854                                                      
REMARK 465     PRO B   855                                                      
REMARK 465     GLU B   856                                                      
REMARK 465     LYS B   857                                                      
REMARK 465     GLY B   858                                                      
REMARK 465     SER B   859                                                      
REMARK 465     TRP B   860                                                      
REMARK 465     GLU B   861                                                      
REMARK 465     GLN B   862                                                      
REMARK 465     LEU B   863                                                      
REMARK 465     SER B   864                                                      
REMARK 465     PRO B   865                                                      
REMARK 465     GLN B   866                                                      
REMARK 465     ASP B   867                                                      
REMARK 465     VAL B   868                                                      
REMARK 465     LEU B   869                                                      
REMARK 465     GLN B   870                                                      
REMARK 465     MET B   871                                                      
REMARK 465     LEU B   872                                                      
REMARK 465     GLY B   873                                                      
REMARK 465     ARG B   874                                                      
REMARK 465     ALA B   875                                                      
REMARK 465     GLY B   876                                                      
REMARK 465     ARG B   877                                                      
REMARK 465     PRO B   878                                                      
REMARK 465     ARG B   879                                                      
REMARK 465     TYR B   880                                                      
REMARK 465     ASP B   881                                                      
REMARK 465     THR B   882                                                      
REMARK 465     PHE B   883                                                      
REMARK 465     GLY B   884                                                      
REMARK 465     GLU B   885                                                      
REMARK 465     GLY B   886                                                      
REMARK 465     ILE B   887                                                      
REMARK 465     ILE B   888                                                      
REMARK 465     ILE B   889                                                      
REMARK 465     THR B   890                                                      
REMARK 465     ASP B   891                                                      
REMARK 465     GLN B   892                                                      
REMARK 465     SER B   893                                                      
REMARK 465     ASN B   894                                                      
REMARK 465     VAL B   895                                                      
REMARK 465     GLN B   896                                                      
REMARK 465     TYR B   897                                                      
REMARK 465     TYR B   898                                                      
REMARK 465     LEU B   899                                                      
REMARK 465     SER B   900                                                      
REMARK 465     VAL B   901                                                      
REMARK 465     LEU B   902                                                      
REMARK 465     ASN B   903                                                      
REMARK 465     GLN B   904                                                      
REMARK 465     GLN B   905                                                      
REMARK 465     LEU B   906                                                      
REMARK 465     PRO B   907                                                      
REMARK 465     ILE B   908                                                      
REMARK 465     GLU B   909                                                      
REMARK 465     SER B   910                                                      
REMARK 465     GLN B   911                                                      
REMARK 465     PHE B   912                                                      
REMARK 465     VAL B   913                                                      
REMARK 465     SER B   914                                                      
REMARK 465     LYS B   915                                                      
REMARK 465     LEU B   916                                                      
REMARK 465     VAL B   917                                                      
REMARK 465     ASP B   918                                                      
REMARK 465     ASN B   919                                                      
REMARK 465     LEU B   920                                                      
REMARK 465     ASN B   921                                                      
REMARK 465     ALA B   922                                                      
REMARK 465     GLU B   923                                                      
REMARK 465     VAL B   924                                                      
REMARK 465     VAL B   925                                                      
REMARK 465     ALA B   926                                                      
REMARK 465     GLY B   927                                                      
REMARK 465     ASN B   928                                                      
REMARK 465     ILE B   929                                                      
REMARK 465     LYS B   930                                                      
REMARK 465     CYS B   931                                                      
REMARK 465     ARG B   932                                                      
REMARK 465     ASN B   933                                                      
REMARK 465     ASP B   934                                                      
REMARK 465     ALA B   935                                                      
REMARK 465     VAL B   936                                                      
REMARK 465     ASN B   937                                                      
REMARK 465     TRP B   938                                                      
REMARK 465     LEU B   939                                                      
REMARK 465     ALA B   940                                                      
REMARK 465     TYR B   941                                                      
REMARK 465     THR B   942                                                      
REMARK 465     TYR B   943                                                      
REMARK 465     LEU B   944                                                      
REMARK 465     TYR B   945                                                      
REMARK 465     VAL B   946                                                      
REMARK 465     ARG B   947                                                      
REMARK 465     MET B   948                                                      
REMARK 465     LEU B   949                                                      
REMARK 465     ALA B   950                                                      
REMARK 465     SER B   951                                                      
REMARK 465     PRO B   952                                                      
REMARK 465     MET B   953                                                      
REMARK 465     LEU B   954                                                      
REMARK 465     TYR B   955                                                      
REMARK 465     LYS B   956                                                      
REMARK 465     VAL B   957                                                      
REMARK 465     PRO B   958                                                      
REMARK 465     ASP B   959                                                      
REMARK 465     ILE B   960                                                      
REMARK 465     SER B   961                                                      
REMARK 465     SER B   962                                                      
REMARK 465     ASP B   963                                                      
REMARK 465     GLY B   964                                                      
REMARK 465     GLN B   965                                                      
REMARK 465     LEU B   966                                                      
REMARK 465     LYS B   967                                                      
REMARK 465     LYS B   968                                                      
REMARK 465     PHE B   969                                                      
REMARK 465     ARG B   970                                                      
REMARK 465     GLU B   971                                                      
REMARK 465     SER B   972                                                      
REMARK 465     LEU B   973                                                      
REMARK 465     VAL B   974                                                      
REMARK 465     HIS B   975                                                      
REMARK 465     SER B   976                                                      
REMARK 465     ALA B   977                                                      
REMARK 465     LEU B   978                                                      
REMARK 465     CYS B   979                                                      
REMARK 465     ILE B   980                                                      
REMARK 465     LEU B   981                                                      
REMARK 465     LYS B   982                                                      
REMARK 465     GLU B   983                                                      
REMARK 465     GLN B   984                                                      
REMARK 465     GLU B   985                                                      
REMARK 465     LEU B   986                                                      
REMARK 465     VAL B   987                                                      
REMARK 465     LEU B   988                                                      
REMARK 465     TYR B   989                                                      
REMARK 465     ASP B   990                                                      
REMARK 465     ALA B   991                                                      
REMARK 465     GLU B   992                                                      
REMARK 465     ASN B   993                                                      
REMARK 465     ASP B   994                                                      
REMARK 465     VAL B   995                                                      
REMARK 465     ILE B   996                                                      
REMARK 465     GLU B   997                                                      
REMARK 465     ALA B   998                                                      
REMARK 465     THR B   999                                                      
REMARK 465     ASP B  1000                                                      
REMARK 465     LEU B  1001                                                      
REMARK 465     GLY B  1002                                                      
REMARK 465     ASN B  1003                                                      
REMARK 465     ILE B  1004                                                      
REMARK 465     ALA B  1005                                                      
REMARK 465     SER B  1006                                                      
REMARK 465     SER B  1007                                                      
REMARK 465     PHE B  1008                                                      
REMARK 465     TYR B  1009                                                      
REMARK 465     ILE B  1010                                                      
REMARK 465     ASN B  1011                                                      
REMARK 465     HIS B  1012                                                      
REMARK 465     ALA B  1013                                                      
REMARK 465     SER B  1014                                                      
REMARK 465     MET B  1015                                                      
REMARK 465     ASP B  1016                                                      
REMARK 465     VAL B  1017                                                      
REMARK 465     TYR B  1018                                                      
REMARK 465     ASN B  1019                                                      
REMARK 465     ARG B  1020                                                      
REMARK 465     GLU B  1021                                                      
REMARK 465     LEU B  1022                                                      
REMARK 465     ASP B  1023                                                      
REMARK 465     GLU B  1024                                                      
REMARK 465     HIS B  1025                                                      
REMARK 465     THR B  1026                                                      
REMARK 465     THR B  1027                                                      
REMARK 465     GLN B  1028                                                      
REMARK 465     ILE B  1029                                                      
REMARK 465     ASP B  1030                                                      
REMARK 465     LEU B  1031                                                      
REMARK 465     PHE B  1032                                                      
REMARK 465     ARG B  1033                                                      
REMARK 465     ILE B  1034                                                      
REMARK 465     PHE B  1035                                                      
REMARK 465     SER B  1036                                                      
REMARK 465     MET B  1037                                                      
REMARK 465     SER B  1038                                                      
REMARK 465     GLU B  1039                                                      
REMARK 465     GLU B  1040                                                      
REMARK 465     PHE B  1041                                                      
REMARK 465     LYS B  1042                                                      
REMARK 465     TYR B  1043                                                      
REMARK 465     VAL B  1044                                                      
REMARK 465     SER B  1045                                                      
REMARK 465     VAL B  1046                                                      
REMARK 465     ARG B  1047                                                      
REMARK 465     TYR B  1048                                                      
REMARK 465     GLU B  1049                                                      
REMARK 465     GLU B  1050                                                      
REMARK 465     LYS B  1051                                                      
REMARK 465     ARG B  1052                                                      
REMARK 465     GLU B  1053                                                      
REMARK 465     LEU B  1054                                                      
REMARK 465     LYS B  1055                                                      
REMARK 465     GLN B  1056                                                      
REMARK 465     LEU B  1057                                                      
REMARK 465     LEU B  1058                                                      
REMARK 465     GLU B  1059                                                      
REMARK 465     LYS B  1060                                                      
REMARK 465     ALA B  1061                                                      
REMARK 465     PRO B  1062                                                      
REMARK 465     ILE B  1063                                                      
REMARK 465     PRO B  1064                                                      
REMARK 465     ILE B  1065                                                      
REMARK 465     ARG B  1066                                                      
REMARK 465     GLU B  1067                                                      
REMARK 465     ASP B  1068                                                      
REMARK 465     ILE B  1069                                                      
REMARK 465     ASP B  1070                                                      
REMARK 465     ASP B  1071                                                      
REMARK 465     PRO B  1072                                                      
REMARK 465     LEU B  1073                                                      
REMARK 465     ALA B  1074                                                      
REMARK 465     LYS B  1075                                                      
REMARK 465     VAL B  1076                                                      
REMARK 465     ASN B  1077                                                      
REMARK 465     VAL B  1078                                                      
REMARK 465     LEU B  1079                                                      
REMARK 465     LEU B  1080                                                      
REMARK 465     GLN B  1081                                                      
REMARK 465     SER B  1082                                                      
REMARK 465     TYR B  1083                                                      
REMARK 465     PHE B  1084                                                      
REMARK 465     SER B  1085                                                      
REMARK 465     GLN B  1086                                                      
REMARK 465     LEU B  1087                                                      
REMARK 465     LYS B  1088                                                      
REMARK 465     PHE B  1089                                                      
REMARK 465     GLU B  1090                                                      
REMARK 465     GLY B  1091                                                      
REMARK 465     PHE B  1092                                                      
REMARK 465     ALA B  1093                                                      
REMARK 465     LEU B  1094                                                      
REMARK 465     ASN B  1095                                                      
REMARK 465     SER B  1096                                                      
REMARK 465     ASP B  1097                                                      
REMARK 465     ILE B  1098                                                      
REMARK 465     VAL B  1099                                                      
REMARK 465     PHE B  1100                                                      
REMARK 465     ILE B  1101                                                      
REMARK 465     HIS B  1102                                                      
REMARK 465     GLN B  1103                                                      
REMARK 465     ASN B  1104                                                      
REMARK 465     ALA B  1105                                                      
REMARK 465     GLY B  1106                                                      
REMARK 465     ARG B  1107                                                      
REMARK 465     LEU B  1108                                                      
REMARK 465     LEU B  1109                                                      
REMARK 465     ARG B  1110                                                      
REMARK 465     ALA B  1111                                                      
REMARK 465     MET B  1112                                                      
REMARK 465     PHE B  1113                                                      
REMARK 465     GLU B  1114                                                      
REMARK 465     ILE B  1115                                                      
REMARK 465     CYS B  1116                                                      
REMARK 465     LEU B  1117                                                      
REMARK 465     LYS B  1118                                                      
REMARK 465     ARG B  1119                                                      
REMARK 465     GLY B  1120                                                      
REMARK 465     TRP B  1121                                                      
REMARK 465     GLY B  1122                                                      
REMARK 465     HIS B  1123                                                      
REMARK 465     PRO B  1124                                                      
REMARK 465     THR B  1125                                                      
REMARK 465     ARG B  1126                                                      
REMARK 465     MET B  1127                                                      
REMARK 465     LEU B  1128                                                      
REMARK 465     LEU B  1129                                                      
REMARK 465     ASN B  1130                                                      
REMARK 465     LEU B  1131                                                      
REMARK 465     CYS B  1132                                                      
REMARK 465     LYS B  1133                                                      
REMARK 465     SER B  1134                                                      
REMARK 465     ALA B  1135                                                      
REMARK 465     THR B  1136                                                      
REMARK 465     THR B  1137                                                      
REMARK 465     LYS B  1138                                                      
REMARK 465     MET B  1139                                                      
REMARK 465     TRP B  1140                                                      
REMARK 465     PRO B  1141                                                      
REMARK 465     THR B  1142                                                      
REMARK 465     ASN B  1143                                                      
REMARK 465     CYS B  1144                                                      
REMARK 465     PRO B  1145                                                      
REMARK 465     LEU B  1146                                                      
REMARK 465     ARG B  1147                                                      
REMARK 465     GLN B  1148                                                      
REMARK 465     PHE B  1149                                                      
REMARK 465     LYS B  1150                                                      
REMARK 465     THR B  1151                                                      
REMARK 465     CYS B  1152                                                      
REMARK 465     PRO B  1153                                                      
REMARK 465     VAL B  1154                                                      
REMARK 465     GLU B  1155                                                      
REMARK 465     VAL B  1156                                                      
REMARK 465     ILE B  1157                                                      
REMARK 465     LYS B  1158                                                      
REMARK 465     ARG B  1159                                                      
REMARK 465     LEU B  1160                                                      
REMARK 465     GLU B  1161                                                      
REMARK 465     ALA B  1162                                                      
REMARK 465     SER B  1163                                                      
REMARK 465     THR B  1164                                                      
REMARK 465     VAL B  1165                                                      
REMARK 465     PRO B  1166                                                      
REMARK 465     TRP B  1167                                                      
REMARK 465     GLY B  1168                                                      
REMARK 465     ASP B  1169                                                      
REMARK 465     TYR B  1170                                                      
REMARK 465     LEU B  1171                                                      
REMARK 465     GLN B  1172                                                      
REMARK 465     LEU B  1173                                                      
REMARK 465     GLU B  1174                                                      
REMARK 465     THR B  1175                                                      
REMARK 465     PRO B  1176                                                      
REMARK 465     ALA B  1177                                                      
REMARK 465     GLU B  1178                                                      
REMARK 465     VAL B  1179                                                      
REMARK 465     GLY B  1180                                                      
REMARK 465     ARG B  1181                                                      
REMARK 465     ALA B  1182                                                      
REMARK 465     ILE B  1183                                                      
REMARK 465     ARG B  1184                                                      
REMARK 465     SER B  1185                                                      
REMARK 465     GLU B  1186                                                      
REMARK 465     LYS B  1187                                                      
REMARK 465     TYR B  1188                                                      
REMARK 465     GLY B  1189                                                      
REMARK 465     LYS B  1190                                                      
REMARK 465     GLN B  1191                                                      
REMARK 465     VAL B  1192                                                      
REMARK 465     TYR B  1193                                                      
REMARK 465     ASP B  1194                                                      
REMARK 465     LEU B  1195                                                      
REMARK 465     LEU B  1196                                                      
REMARK 465     LYS B  1197                                                      
REMARK 465     ARG B  1198                                                      
REMARK 465     PHE B  1199                                                      
REMARK 465     PRO B  1200                                                      
REMARK 465     LYS B  1201                                                      
REMARK 465     MET B  1202                                                      
REMARK 465     SER B  1203                                                      
REMARK 465     VAL B  1204                                                      
REMARK 465     THR B  1205                                                      
REMARK 465     CYS B  1206                                                      
REMARK 465     ASN B  1207                                                      
REMARK 465     ALA B  1208                                                      
REMARK 465     GLN B  1209                                                      
REMARK 465     PRO B  1210                                                      
REMARK 465     ILE B  1211                                                      
REMARK 465     THR B  1212                                                      
REMARK 465     ARG B  1213                                                      
REMARK 465     SER B  1214                                                      
REMARK 465     VAL B  1215                                                      
REMARK 465     MET B  1216                                                      
REMARK 465     ARG B  1217                                                      
REMARK 465     PHE B  1218                                                      
REMARK 465     ASN B  1219                                                      
REMARK 465     ILE B  1220                                                      
REMARK 465     GLU B  1221                                                      
REMARK 465     ILE B  1222                                                      
REMARK 465     ILE B  1223                                                      
REMARK 465     ALA B  1224                                                      
REMARK 465     ASP B  1225                                                      
REMARK 465     TRP B  1226                                                      
REMARK 465     ILE B  1227                                                      
REMARK 465     TRP B  1228                                                      
REMARK 465     ASP B  1229                                                      
REMARK 465     MET B  1230                                                      
REMARK 465     ASN B  1231                                                      
REMARK 465     VAL B  1232                                                      
REMARK 465     HIS B  1233                                                      
REMARK 465     GLY B  1234                                                      
REMARK 465     SER B  1235                                                      
REMARK 465     LEU B  1236                                                      
REMARK 465     GLU B  1237                                                      
REMARK 465     PRO B  1238                                                      
REMARK 465     PHE B  1239                                                      
REMARK 465     LEU B  1240                                                      
REMARK 465     LEU B  1241                                                      
REMARK 465     MET B  1242                                                      
REMARK 465     LEU B  1243                                                      
REMARK 465     GLU B  1244                                                      
REMARK 465     ASP B  1245                                                      
REMARK 465     THR B  1246                                                      
REMARK 465     ASP B  1247                                                      
REMARK 465     GLY B  1248                                                      
REMARK 465     ASP B  1249                                                      
REMARK 465     SER B  1250                                                      
REMARK 465     ILE B  1251                                                      
REMARK 465     LEU B  1252                                                      
REMARK 465     TYR B  1253                                                      
REMARK 465     TYR B  1254                                                      
REMARK 465     ASP B  1255                                                      
REMARK 465     VAL B  1256                                                      
REMARK 465     LEU B  1257                                                      
REMARK 465     PHE B  1258                                                      
REMARK 465     ILE B  1259                                                      
REMARK 465     THR B  1260                                                      
REMARK 465     PRO B  1261                                                      
REMARK 465     ASP B  1262                                                      
REMARK 465     ILE B  1263                                                      
REMARK 465     VAL B  1264                                                      
REMARK 465     GLY B  1265                                                      
REMARK 465     HIS B  1266                                                      
REMARK 465     GLU B  1267                                                      
REMARK 465     PHE B  1268                                                      
REMARK 465     THR B  1269                                                      
REMARK 465     LEU B  1270                                                      
REMARK 465     SER B  1271                                                      
REMARK 465     PHE B  1272                                                      
REMARK 465     THR B  1273                                                      
REMARK 465     TYR B  1274                                                      
REMARK 465     GLU B  1275                                                      
REMARK 465     LEU B  1276                                                      
REMARK 465     LYS B  1277                                                      
REMARK 465     GLN B  1278                                                      
REMARK 465     HIS B  1279                                                      
REMARK 465     ASN B  1280                                                      
REMARK 465     GLN B  1281                                                      
REMARK 465     ASN B  1282                                                      
REMARK 465     ASN B  1283                                                      
REMARK 465     LEU B  1284                                                      
REMARK 465     PRO B  1285                                                      
REMARK 465     PRO B  1286                                                      
REMARK 465     ASN B  1287                                                      
REMARK 465     PHE B  1288                                                      
REMARK 465     PHE B  1289                                                      
REMARK 465     LEU B  1290                                                      
REMARK 465     THR B  1291                                                      
REMARK 465     LEU B  1292                                                      
REMARK 465     ILE B  1293                                                      
REMARK 465     SER B  1294                                                      
REMARK 465     GLU B  1295                                                      
REMARK 465     ASN B  1296                                                      
REMARK 465     TRP B  1297                                                      
REMARK 465     TRP B  1298                                                      
REMARK 465     HIS B  1299                                                      
REMARK 465     SER B  1300                                                      
REMARK 465     GLU B  1301                                                      
REMARK 465     PHE B  1302                                                      
REMARK 465     GLU B  1303                                                      
REMARK 465     ILE B  1304                                                      
REMARK 465     PRO B  1305                                                      
REMARK 465     VAL B  1306                                                      
REMARK 465     SER B  1307                                                      
REMARK 465     PHE B  1308                                                      
REMARK 465     ASN B  1309                                                      
REMARK 465     GLY B  1310                                                      
REMARK 465     PHE B  1311                                                      
REMARK 465     LYS B  1312                                                      
REMARK 465     LEU B  1313                                                      
REMARK 465     PRO B  1314                                                      
REMARK 465     LYS B  1315                                                      
REMARK 465     LYS B  1316                                                      
REMARK 465     PHE B  1317                                                      
REMARK 465     PRO B  1318                                                      
REMARK 465     PRO B  1319                                                      
REMARK 465     PRO B  1320                                                      
REMARK 465     THR B  1321                                                      
REMARK 465     PRO B  1322                                                      
REMARK 465     LEU B  1323                                                      
REMARK 465     LEU B  1324                                                      
REMARK 465     GLU B  1325                                                      
REMARK 465     ASN B  1326                                                      
REMARK 465     ILE B  1327                                                      
REMARK 465     SER B  1328                                                      
REMARK 465     ILE B  1329                                                      
REMARK 465     SER B  1330                                                      
REMARK 465     THR B  1331                                                      
REMARK 465     SER B  1332                                                      
REMARK 465     GLU B  1333                                                      
REMARK 465     LEU B  1334                                                      
REMARK 465     GLY B  1335                                                      
REMARK 465     ASN B  1336                                                      
REMARK 465     ASP B  1337                                                      
REMARK 465     ASP B  1338                                                      
REMARK 465     PHE B  1339                                                      
REMARK 465     SER B  1340                                                      
REMARK 465     GLU B  1341                                                      
REMARK 465     VAL B  1342                                                      
REMARK 465     PHE B  1343                                                      
REMARK 465     GLU B  1344                                                      
REMARK 465     PHE B  1345                                                      
REMARK 465     LYS B  1346                                                      
REMARK 465     THR B  1347                                                      
REMARK 465     PHE B  1348                                                      
REMARK 465     ASN B  1349                                                      
REMARK 465     LYS B  1350                                                      
REMARK 465     ILE B  1351                                                      
REMARK 465     GLN B  1352                                                      
REMARK 465     SER B  1353                                                      
REMARK 465     GLN B  1354                                                      
REMARK 465     VAL B  1355                                                      
REMARK 465     PHE B  1356                                                      
REMARK 465     GLU B  1357                                                      
REMARK 465     SER B  1358                                                      
REMARK 465     LEU B  1359                                                      
REMARK 465     TYR B  1360                                                      
REMARK 465     ASN B  1361                                                      
REMARK 465     SER B  1362                                                      
REMARK 465     ASN B  1363                                                      
REMARK 465     ASP B  1364                                                      
REMARK 465     SER B  1365                                                      
REMARK 465     VAL B  1366                                                      
REMARK 465     PHE B  1367                                                      
REMARK 465     VAL B  1368                                                      
REMARK 465     GLY B  1369                                                      
REMARK 465     SER B  1370                                                      
REMARK 465     GLY B  1371                                                      
REMARK 465     LYS B  1372                                                      
REMARK 465     GLY B  1373                                                      
REMARK 465     THR B  1374                                                      
REMARK 465     GLY B  1375                                                      
REMARK 465     LYS B  1376                                                      
REMARK 465     THR B  1377                                                      
REMARK 465     ALA B  1378                                                      
REMARK 465     MET B  1379                                                      
REMARK 465     ALA B  1380                                                      
REMARK 465     GLU B  1381                                                      
REMARK 465     LEU B  1382                                                      
REMARK 465     ALA B  1383                                                      
REMARK 465     LEU B  1384                                                      
REMARK 465     LEU B  1385                                                      
REMARK 465     ASN B  1386                                                      
REMARK 465     HIS B  1387                                                      
REMARK 465     TRP B  1388                                                      
REMARK 465     ARG B  1389                                                      
REMARK 465     GLN B  1390                                                      
REMARK 465     ASN B  1391                                                      
REMARK 465     LYS B  1392                                                      
REMARK 465     GLY B  1393                                                      
REMARK 465     ARG B  1394                                                      
REMARK 465     ALA B  1395                                                      
REMARK 465     VAL B  1396                                                      
REMARK 465     TYR B  1397                                                      
REMARK 465     ILE B  1398                                                      
REMARK 465     ASN B  1399                                                      
REMARK 465     PRO B  1400                                                      
REMARK 465     SER B  1401                                                      
REMARK 465     GLY B  1402                                                      
REMARK 465     GLU B  1403                                                      
REMARK 465     LYS B  1404                                                      
REMARK 465     ILE B  1405                                                      
REMARK 465     ASP B  1406                                                      
REMARK 465     PHE B  1407                                                      
REMARK 465     LEU B  1408                                                      
REMARK 465     LEU B  1409                                                      
REMARK 465     SER B  1410                                                      
REMARK 465     ASP B  1411                                                      
REMARK 465     TRP B  1412                                                      
REMARK 465     ASN B  1413                                                      
REMARK 465     LYS B  1414                                                      
REMARK 465     ARG B  1415                                                      
REMARK 465     PHE B  1416                                                      
REMARK 465     SER B  1417                                                      
REMARK 465     HIS B  1418                                                      
REMARK 465     LEU B  1419                                                      
REMARK 465     ALA B  1420                                                      
REMARK 465     GLY B  1421                                                      
REMARK 465     GLY B  1422                                                      
REMARK 465     LYS B  1423                                                      
REMARK 465     ILE B  1424                                                      
REMARK 465     ILE B  1425                                                      
REMARK 465     ASN B  1426                                                      
REMARK 465     LYS B  1427                                                      
REMARK 465     LEU B  1428                                                      
REMARK 465     GLY B  1429                                                      
REMARK 465     ASN B  1430                                                      
REMARK 465     ASP B  1431                                                      
REMARK 465     PRO B  1432                                                      
REMARK 465     SER B  1433                                                      
REMARK 465     LEU B  1434                                                      
REMARK 465     ASN B  1435                                                      
REMARK 465     LEU B  1436                                                      
REMARK 465     LYS B  1437                                                      
REMARK 465     LEU B  1438                                                      
REMARK 465     LEU B  1439                                                      
REMARK 465     ALA B  1440                                                      
REMARK 465     LYS B  1441                                                      
REMARK 465     SER B  1442                                                      
REMARK 465     HIS B  1443                                                      
REMARK 465     VAL B  1444                                                      
REMARK 465     LEU B  1445                                                      
REMARK 465     LEU B  1446                                                      
REMARK 465     ALA B  1447                                                      
REMARK 465     THR B  1448                                                      
REMARK 465     PRO B  1449                                                      
REMARK 465     VAL B  1450                                                      
REMARK 465     GLN B  1451                                                      
REMARK 465     PHE B  1452                                                      
REMARK 465     GLU B  1453                                                      
REMARK 465     LEU B  1454                                                      
REMARK 465     LEU B  1455                                                      
REMARK 465     SER B  1456                                                      
REMARK 465     ARG B  1457                                                      
REMARK 465     ARG B  1458                                                      
REMARK 465     TRP B  1459                                                      
REMARK 465     ARG B  1460                                                      
REMARK 465     GLN B  1461                                                      
REMARK 465     ARG B  1462                                                      
REMARK 465     LYS B  1463                                                      
REMARK 465     ASN B  1464                                                      
REMARK 465     ILE B  1465                                                      
REMARK 465     GLN B  1466                                                      
REMARK 465     SER B  1467                                                      
REMARK 465     LEU B  1468                                                      
REMARK 465     GLU B  1469                                                      
REMARK 465     LEU B  1470                                                      
REMARK 465     MET B  1471                                                      
REMARK 465     ILE B  1472                                                      
REMARK 465     TYR B  1473                                                      
REMARK 465     ASP B  1474                                                      
REMARK 465     ASP B  1475                                                      
REMARK 465     ALA B  1476                                                      
REMARK 465     HIS B  1477                                                      
REMARK 465     GLU B  1478                                                      
REMARK 465     ILE B  1479                                                      
REMARK 465     SER B  1480                                                      
REMARK 465     GLN B  1481                                                      
REMARK 465     GLY B  1482                                                      
REMARK 465     VAL B  1483                                                      
REMARK 465     TYR B  1484                                                      
REMARK 465     GLY B  1485                                                      
REMARK 465     ALA B  1486                                                      
REMARK 465     VAL B  1487                                                      
REMARK 465     TYR B  1488                                                      
REMARK 465     GLU B  1489                                                      
REMARK 465     THR B  1490                                                      
REMARK 465     LEU B  1491                                                      
REMARK 465     ILE B  1492                                                      
REMARK 465     SER B  1493                                                      
REMARK 465     ARG B  1494                                                      
REMARK 465     MET B  1495                                                      
REMARK 465     ILE B  1496                                                      
REMARK 465     PHE B  1497                                                      
REMARK 465     ILE B  1498                                                      
REMARK 465     ALA B  1499                                                      
REMARK 465     THR B  1500                                                      
REMARK 465     GLN B  1501                                                      
REMARK 465     LEU B  1502                                                      
REMARK 465     GLU B  1503                                                      
REMARK 465     LYS B  1504                                                      
REMARK 465     LYS B  1505                                                      
REMARK 465     ILE B  1506                                                      
REMARK 465     ARG B  1507                                                      
REMARK 465     PHE B  1508                                                      
REMARK 465     VAL B  1509                                                      
REMARK 465     CYS B  1510                                                      
REMARK 465     LEU B  1511                                                      
REMARK 465     SER B  1512                                                      
REMARK 465     ASN B  1513                                                      
REMARK 465     CYS B  1514                                                      
REMARK 465     LEU B  1515                                                      
REMARK 465     ALA B  1516                                                      
REMARK 465     ASN B  1517                                                      
REMARK 465     ALA B  1518                                                      
REMARK 465     ARG B  1519                                                      
REMARK 465     ASP B  1520                                                      
REMARK 465     PHE B  1521                                                      
REMARK 465     GLY B  1522                                                      
REMARK 465     GLU B  1523                                                      
REMARK 465     TRP B  1524                                                      
REMARK 465     ALA B  1525                                                      
REMARK 465     GLY B  1526                                                      
REMARK 465     MET B  1527                                                      
REMARK 465     THR B  1528                                                      
REMARK 465     LYS B  1529                                                      
REMARK 465     SER B  1530                                                      
REMARK 465     ASN B  1531                                                      
REMARK 465     ILE B  1532                                                      
REMARK 465     TYR B  1533                                                      
REMARK 465     ASN B  1534                                                      
REMARK 465     PHE B  1535                                                      
REMARK 465     SER B  1536                                                      
REMARK 465     PRO B  1537                                                      
REMARK 465     SER B  1538                                                      
REMARK 465     GLU B  1539                                                      
REMARK 465     ARG B  1540                                                      
REMARK 465     ILE B  1541                                                      
REMARK 465     GLU B  1542                                                      
REMARK 465     PRO B  1543                                                      
REMARK 465     LEU B  1544                                                      
REMARK 465     GLU B  1545                                                      
REMARK 465     ILE B  1546                                                      
REMARK 465     ASN B  1547                                                      
REMARK 465     ILE B  1548                                                      
REMARK 465     GLN B  1549                                                      
REMARK 465     SER B  1550                                                      
REMARK 465     PHE B  1551                                                      
REMARK 465     LYS B  1552                                                      
REMARK 465     ASP B  1553                                                      
REMARK 465     VAL B  1554                                                      
REMARK 465     GLU B  1555                                                      
REMARK 465     HIS B  1556                                                      
REMARK 465     ILE B  1557                                                      
REMARK 465     SER B  1558                                                      
REMARK 465     PHE B  1559                                                      
REMARK 465     ASN B  1560                                                      
REMARK 465     PHE B  1561                                                      
REMARK 465     SER B  1562                                                      
REMARK 465     MET B  1563                                                      
REMARK 465     LEU B  1564                                                      
REMARK 465     GLN B  1565                                                      
REMARK 465     MET B  1566                                                      
REMARK 465     ALA B  1567                                                      
REMARK 465     PHE B  1568                                                      
REMARK 465     GLU B  1569                                                      
REMARK 465     ALA B  1570                                                      
REMARK 465     SER B  1571                                                      
REMARK 465     ALA B  1572                                                      
REMARK 465     ALA B  1573                                                      
REMARK 465     ALA B  1574                                                      
REMARK 465     ALA B  1575                                                      
REMARK 465     GLY B  1576                                                      
REMARK 465     ASN B  1577                                                      
REMARK 465     ARG B  1578                                                      
REMARK 465     ASN B  1579                                                      
REMARK 465     SER B  1580                                                      
REMARK 465     SER B  1581                                                      
REMARK 465     SER B  1582                                                      
REMARK 465     VAL B  1583                                                      
REMARK 465     PHE B  1584                                                      
REMARK 465     LEU B  1585                                                      
REMARK 465     PRO B  1586                                                      
REMARK 465     SER B  1587                                                      
REMARK 465     ARG B  1588                                                      
REMARK 465     LYS B  1589                                                      
REMARK 465     ASP B  1590                                                      
REMARK 465     CYS B  1591                                                      
REMARK 465     MET B  1592                                                      
REMARK 465     GLU B  1593                                                      
REMARK 465     VAL B  1594                                                      
REMARK 465     ALA B  1595                                                      
REMARK 465     SER B  1596                                                      
REMARK 465     ALA B  1597                                                      
REMARK 465     PHE B  1598                                                      
REMARK 465     MET B  1599                                                      
REMARK 465     LYS B  1600                                                      
REMARK 465     PHE B  1601                                                      
REMARK 465     SER B  1602                                                      
REMARK 465     LYS B  1603                                                      
REMARK 465     ALA B  1604                                                      
REMARK 465     ILE B  1605                                                      
REMARK 465     GLU B  1606                                                      
REMARK 465     TRP B  1607                                                      
REMARK 465     ASP B  1608                                                      
REMARK 465     MET B  1609                                                      
REMARK 465     LEU B  1610                                                      
REMARK 465     ASN B  1611                                                      
REMARK 465     VAL B  1612                                                      
REMARK 465     GLU B  1613                                                      
REMARK 465     GLU B  1614                                                      
REMARK 465     GLU B  1615                                                      
REMARK 465     GLN B  1616                                                      
REMARK 465     ILE B  1617                                                      
REMARK 465     VAL B  1618                                                      
REMARK 465     PRO B  1619                                                      
REMARK 465     TYR B  1620                                                      
REMARK 465     ILE B  1621                                                      
REMARK 465     GLU B  1622                                                      
REMARK 465     LYS B  1623                                                      
REMARK 465     LEU B  1624                                                      
REMARK 465     THR B  1625                                                      
REMARK 465     ASP B  1626                                                      
REMARK 465     GLY B  1627                                                      
REMARK 465     HIS B  1628                                                      
REMARK 465     LEU B  1629                                                      
REMARK 465     ARG B  1630                                                      
REMARK 465     ALA B  1631                                                      
REMARK 465     PRO B  1632                                                      
REMARK 465     LEU B  1633                                                      
REMARK 465     LYS B  1634                                                      
REMARK 465     HIS B  1635                                                      
REMARK 465     GLY B  1636                                                      
REMARK 465     VAL B  1637                                                      
REMARK 465     GLY B  1638                                                      
REMARK 465     ILE B  1639                                                      
REMARK 465     LEU B  1640                                                      
REMARK 465     TYR B  1641                                                      
REMARK 465     LYS B  1642                                                      
REMARK 465     GLY B  1643                                                      
REMARK 465     MET B  1644                                                      
REMARK 465     ALA B  1645                                                      
REMARK 465     SER B  1646                                                      
REMARK 465     ASN B  1647                                                      
REMARK 465     ASP B  1648                                                      
REMARK 465     GLU B  1649                                                      
REMARK 465     ARG B  1650                                                      
REMARK 465     ILE B  1651                                                      
REMARK 465     VAL B  1652                                                      
REMARK 465     LYS B  1653                                                      
REMARK 465     ARG B  1654                                                      
REMARK 465     LEU B  1655                                                      
REMARK 465     TYR B  1656                                                      
REMARK 465     GLU B  1657                                                      
REMARK 465     TYR B  1658                                                      
REMARK 465     GLY B  1659                                                      
REMARK 465     ALA B  1660                                                      
REMARK 465     VAL B  1661                                                      
REMARK 465     SER B  1662                                                      
REMARK 465     VAL B  1663                                                      
REMARK 465     LEU B  1664                                                      
REMARK 465     LEU B  1665                                                      
REMARK 465     ILE B  1666                                                      
REMARK 465     SER B  1667                                                      
REMARK 465     LYS B  1668                                                      
REMARK 465     ASP B  1669                                                      
REMARK 465     CYS B  1670                                                      
REMARK 465     SER B  1671                                                      
REMARK 465     ALA B  1672                                                      
REMARK 465     PHE B  1673                                                      
REMARK 465     ALA B  1674                                                      
REMARK 465     CYS B  1675                                                      
REMARK 465     LYS B  1676                                                      
REMARK 465     THR B  1677                                                      
REMARK 465     ASP B  1678                                                      
REMARK 465     GLU B  1679                                                      
REMARK 465     VAL B  1680                                                      
REMARK 465     ILE B  1681                                                      
REMARK 465     ILE B  1682                                                      
REMARK 465     LEU B  1683                                                      
REMARK 465     GLY B  1684                                                      
REMARK 465     THR B  1685                                                      
REMARK 465     ASN B  1686                                                      
REMARK 465     LEU B  1687                                                      
REMARK 465     TYR B  1688                                                      
REMARK 465     ASP B  1689                                                      
REMARK 465     GLY B  1690                                                      
REMARK 465     ALA B  1691                                                      
REMARK 465     GLU B  1692                                                      
REMARK 465     HIS B  1693                                                      
REMARK 465     LYS B  1694                                                      
REMARK 465     TYR B  1695                                                      
REMARK 465     MET B  1696                                                      
REMARK 465     PRO B  1697                                                      
REMARK 465     TYR B  1698                                                      
REMARK 465     THR B  1699                                                      
REMARK 465     ILE B  1700                                                      
REMARK 465     ASN B  1701                                                      
REMARK 465     GLU B  1702                                                      
REMARK 465     LEU B  1703                                                      
REMARK 465     LEU B  1704                                                      
REMARK 465     GLU B  1705                                                      
REMARK 465     MET B  1706                                                      
REMARK 465     VAL B  1707                                                      
REMARK 465     GLY B  1708                                                      
REMARK 465     LEU B  1709                                                      
REMARK 465     ALA B  1710                                                      
REMARK 465     SER B  1711                                                      
REMARK 465     GLY B  1712                                                      
REMARK 465     ASN B  1713                                                      
REMARK 465     ASP B  1714                                                      
REMARK 465     SER B  1715                                                      
REMARK 465     MET B  1716                                                      
REMARK 465     ALA B  1717                                                      
REMARK 465     GLY B  1718                                                      
REMARK 465     LYS B  1719                                                      
REMARK 465     VAL B  1720                                                      
REMARK 465     LEU B  1721                                                      
REMARK 465     ILE B  1722                                                      
REMARK 465     LEU B  1723                                                      
REMARK 465     THR B  1724                                                      
REMARK 465     SER B  1725                                                      
REMARK 465     HIS B  1726                                                      
REMARK 465     ASN B  1727                                                      
REMARK 465     MET B  1728                                                      
REMARK 465     LYS B  1729                                                      
REMARK 465     ALA B  1730                                                      
REMARK 465     TYR B  1731                                                      
REMARK 465     TYR B  1732                                                      
REMARK 465     LYS B  1733                                                      
REMARK 465     LYS B  1734                                                      
REMARK 465     PHE B  1735                                                      
REMARK 465     LEU B  1736                                                      
REMARK 465     ILE B  1737                                                      
REMARK 465     GLU B  1738                                                      
REMARK 465     PRO B  1739                                                      
REMARK 465     LEU B  1740                                                      
REMARK 465     PRO B  1741                                                      
REMARK 465     THR B  1742                                                      
REMARK 465     GLU B  1743                                                      
REMARK 465     SER B  1744                                                      
REMARK 465     TYR B  1745                                                      
REMARK 465     LEU B  1746                                                      
REMARK 465     GLN B  1747                                                      
REMARK 465     TYR B  1748                                                      
REMARK 465     ILE B  1749                                                      
REMARK 465     ILE B  1750                                                      
REMARK 465     HIS B  1751                                                      
REMARK 465     ASP B  1752                                                      
REMARK 465     THR B  1753                                                      
REMARK 465     LEU B  1754                                                      
REMARK 465     ASN B  1755                                                      
REMARK 465     ASN B  1756                                                      
REMARK 465     GLU B  1757                                                      
REMARK 465     ILE B  1758                                                      
REMARK 465     ALA B  1759                                                      
REMARK 465     ASN B  1760                                                      
REMARK 465     SER B  1761                                                      
REMARK 465     ILE B  1762                                                      
REMARK 465     ILE B  1763                                                      
REMARK 465     GLN B  1764                                                      
REMARK 465     SER B  1765                                                      
REMARK 465     LYS B  1766                                                      
REMARK 465     GLN B  1767                                                      
REMARK 465     ASP B  1768                                                      
REMARK 465     CYS B  1769                                                      
REMARK 465     VAL B  1770                                                      
REMARK 465     ASP B  1771                                                      
REMARK 465     TRP B  1772                                                      
REMARK 465     PHE B  1773                                                      
REMARK 465     THR B  1774                                                      
REMARK 465     TYR B  1775                                                      
REMARK 465     SER B  1776                                                      
REMARK 465     TYR B  1777                                                      
REMARK 465     PHE B  1778                                                      
REMARK 465     TYR B  1779                                                      
REMARK 465     ARG B  1780                                                      
REMARK 465     ARG B  1781                                                      
REMARK 465     ILE B  1782                                                      
REMARK 465     HIS B  1783                                                      
REMARK 465     VAL B  1784                                                      
REMARK 465     ASN B  1785                                                      
REMARK 465     PRO B  1786                                                      
REMARK 465     SER B  1787                                                      
REMARK 465     TYR B  1788                                                      
REMARK 465     TYR B  1789                                                      
REMARK 465     GLY B  1790                                                      
REMARK 465     VAL B  1791                                                      
REMARK 465     ARG B  1792                                                      
REMARK 465     ASP B  1793                                                      
REMARK 465     THR B  1794                                                      
REMARK 465     SER B  1795                                                      
REMARK 465     PRO B  1796                                                      
REMARK 465     HIS B  1797                                                      
REMARK 465     GLY B  1798                                                      
REMARK 465     ILE B  1799                                                      
REMARK 465     SER B  1800                                                      
REMARK 465     VAL B  1801                                                      
REMARK 465     PHE B  1802                                                      
REMARK 465     LEU B  1803                                                      
REMARK 465     SER B  1804                                                      
REMARK 465     ASN B  1805                                                      
REMARK 465     LEU B  1806                                                      
REMARK 465     VAL B  1807                                                      
REMARK 465     GLU B  1808                                                      
REMARK 465     THR B  1809                                                      
REMARK 465     CYS B  1810                                                      
REMARK 465     LEU B  1811                                                      
REMARK 465     ASN B  1812                                                      
REMARK 465     ASP B  1813                                                      
REMARK 465     LEU B  1814                                                      
REMARK 465     VAL B  1815                                                      
REMARK 465     GLU B  1816                                                      
REMARK 465     SER B  1817                                                      
REMARK 465     SER B  1818                                                      
REMARK 465     PHE B  1819                                                      
REMARK 465     ILE B  1820                                                      
REMARK 465     GLU B  1821                                                      
REMARK 465     ILE B  1822                                                      
REMARK 465     ASP B  1823                                                      
REMARK 465     ASP B  1824                                                      
REMARK 465     THR B  1825                                                      
REMARK 465     GLU B  1826                                                      
REMARK 465     ALA B  1827                                                      
REMARK 465     GLU B  1828                                                      
REMARK 465     VAL B  1829                                                      
REMARK 465     THR B  1830                                                      
REMARK 465     ALA B  1831                                                      
REMARK 465     GLU B  1832                                                      
REMARK 465     VAL B  1833                                                      
REMARK 465     ASN B  1834                                                      
REMARK 465     GLY B  1835                                                      
REMARK 465     GLY B  1836                                                      
REMARK 465     ASP B  1837                                                      
REMARK 465     ASP B  1838                                                      
REMARK 465     GLU B  1839                                                      
REMARK 465     ALA B  1840                                                      
REMARK 465     THR B  1841                                                      
REMARK 465     GLU B  1842                                                      
REMARK 465     ILE B  1843                                                      
REMARK 465     ILE B  1844                                                      
REMARK 465     SER B  1845                                                      
REMARK 465     THR B  1846                                                      
REMARK 465     LEU B  1847                                                      
REMARK 465     SER B  1848                                                      
REMARK 465     ASN B  1849                                                      
REMARK 465     GLY B  1850                                                      
REMARK 465     LEU B  1851                                                      
REMARK 465     ILE B  1852                                                      
REMARK 465     ALA B  1853                                                      
REMARK 465     SER B  1854                                                      
REMARK 465     HIS B  1855                                                      
REMARK 465     TYR B  1856                                                      
REMARK 465     GLY B  1857                                                      
REMARK 465     VAL B  1858                                                      
REMARK 465     SER B  1859                                                      
REMARK 465     PHE B  1860                                                      
REMARK 465     PHE B  1861                                                      
REMARK 465     THR B  1862                                                      
REMARK 465     ILE B  1863                                                      
REMARK 465     GLN B  1864                                                      
REMARK 465     SER B  1865                                                      
REMARK 465     PHE B  1866                                                      
REMARK 465     VAL B  1867                                                      
REMARK 465     SER B  1868                                                      
REMARK 465     SER B  1869                                                      
REMARK 465     LEU B  1870                                                      
REMARK 465     SER B  1871                                                      
REMARK 465     ASN B  1872                                                      
REMARK 465     THR B  1873                                                      
REMARK 465     SER B  1874                                                      
REMARK 465     THR B  1875                                                      
REMARK 465     LEU B  1876                                                      
REMARK 465     LYS B  1877                                                      
REMARK 465     ASN B  1878                                                      
REMARK 465     MET B  1879                                                      
REMARK 465     LEU B  1880                                                      
REMARK 465     TYR B  1881                                                      
REMARK 465     VAL B  1882                                                      
REMARK 465     LEU B  1883                                                      
REMARK 465     SER B  1884                                                      
REMARK 465     THR B  1885                                                      
REMARK 465     ALA B  1886                                                      
REMARK 465     VAL B  1887                                                      
REMARK 465     GLU B  1888                                                      
REMARK 465     PHE B  1889                                                      
REMARK 465     GLU B  1890                                                      
REMARK 465     SER B  1891                                                      
REMARK 465     VAL B  1892                                                      
REMARK 465     PRO B  1893                                                      
REMARK 465     LEU B  1894                                                      
REMARK 465     ARG B  1895                                                      
REMARK 465     LYS B  1896                                                      
REMARK 465     GLY B  1897                                                      
REMARK 465     ASP B  1898                                                      
REMARK 465     ARG B  1899                                                      
REMARK 465     ALA B  1900                                                      
REMARK 465     LEU B  1901                                                      
REMARK 465     LEU B  1902                                                      
REMARK 465     VAL B  1903                                                      
REMARK 465     LYS B  1904                                                      
REMARK 465     LEU B  1905                                                      
REMARK 465     SER B  1906                                                      
REMARK 465     LYS B  1907                                                      
REMARK 465     ARG B  1908                                                      
REMARK 465     LEU B  1909                                                      
REMARK 465     PRO B  1910                                                      
REMARK 465     LEU B  1911                                                      
REMARK 465     ARG B  1912                                                      
REMARK 465     PHE B  1913                                                      
REMARK 465     PRO B  1914                                                      
REMARK 465     GLU B  1915                                                      
REMARK 465     HIS B  1916                                                      
REMARK 465     THR B  1917                                                      
REMARK 465     SER B  1918                                                      
REMARK 465     SER B  1919                                                      
REMARK 465     GLY B  1920                                                      
REMARK 465     SER B  1921                                                      
REMARK 465     VAL B  1922                                                      
REMARK 465     SER B  1923                                                      
REMARK 465     PHE B  1924                                                      
REMARK 465     LYS B  1925                                                      
REMARK 465     VAL B  1926                                                      
REMARK 465     PHE B  1927                                                      
REMARK 465     LEU B  1928                                                      
REMARK 465     LEU B  1929                                                      
REMARK 465     LEU B  1930                                                      
REMARK 465     GLN B  1931                                                      
REMARK 465     ALA B  1932                                                      
REMARK 465     TYR B  1933                                                      
REMARK 465     PHE B  1934                                                      
REMARK 465     SER B  1935                                                      
REMARK 465     ARG B  1936                                                      
REMARK 465     LEU B  1937                                                      
REMARK 465     GLU B  1938                                                      
REMARK 465     LEU B  1939                                                      
REMARK 465     PRO B  1940                                                      
REMARK 465     VAL B  1941                                                      
REMARK 465     ASP B  1942                                                      
REMARK 465     PHE B  1943                                                      
REMARK 465     GLN B  1944                                                      
REMARK 465     ASN B  1945                                                      
REMARK 465     ASP B  1946                                                      
REMARK 465     LEU B  1947                                                      
REMARK 465     LYS B  1948                                                      
REMARK 465     ASP B  1949                                                      
REMARK 465     ILE B  1950                                                      
REMARK 465     LEU B  1951                                                      
REMARK 465     GLU B  1952                                                      
REMARK 465     LYS B  1953                                                      
REMARK 465     VAL B  1954                                                      
REMARK 465     VAL B  1955                                                      
REMARK 465     PRO B  1956                                                      
REMARK 465     LEU B  1957                                                      
REMARK 465     ILE B  1958                                                      
REMARK 465     ASN B  1959                                                      
REMARK 465     VAL B  1960                                                      
REMARK 465     VAL B  1961                                                      
REMARK 465     VAL B  1962                                                      
REMARK 465     ASP B  1963                                                      
REMARK 465     ILE B  1964                                                      
REMARK 465     LEU B  1965                                                      
REMARK 465     SER B  1966                                                      
REMARK 465     ALA B  1967                                                      
REMARK 465     ASN B  1968                                                      
REMARK 465     GLY B  1969                                                      
REMARK 465     TYR B  1970                                                      
REMARK 465     LEU B  1971                                                      
REMARK 465     ASN B  1972                                                      
REMARK 465     ALA B  1973                                                      
REMARK 465     THR B  1974                                                      
REMARK 465     THR B  1975                                                      
REMARK 465     ALA B  1976                                                      
REMARK 465     MET B  1977                                                      
REMARK 465     ASP B  1978                                                      
REMARK 465     LEU B  1979                                                      
REMARK 465     ALA B  1980                                                      
REMARK 465     GLN B  1981                                                      
REMARK 465     MET B  1982                                                      
REMARK 465     LEU B  1983                                                      
REMARK 465     ILE B  1984                                                      
REMARK 465     GLN B  1985                                                      
REMARK 465     GLY B  1986                                                      
REMARK 465     VAL B  1987                                                      
REMARK 465     TRP B  1988                                                      
REMARK 465     ASP B  1989                                                      
REMARK 465     VAL B  1990                                                      
REMARK 465     ASP B  1991                                                      
REMARK 465     ASN B  1992                                                      
REMARK 465     PRO B  1993                                                      
REMARK 465     LEU B  1994                                                      
REMARK 465     ARG B  1995                                                      
REMARK 465     GLN B  1996                                                      
REMARK 465     ILE B  1997                                                      
REMARK 465     PRO B  1998                                                      
REMARK 465     HIS B  1999                                                      
REMARK 465     PHE B  2000                                                      
REMARK 465     ASN B  2001                                                      
REMARK 465     ASN B  2002                                                      
REMARK 465     LYS B  2003                                                      
REMARK 465     ILE B  2004                                                      
REMARK 465     LEU B  2005                                                      
REMARK 465     GLU B  2006                                                      
REMARK 465     LYS B  2007                                                      
REMARK 465     CYS B  2008                                                      
REMARK 465     LYS B  2009                                                      
REMARK 465     GLU B  2010                                                      
REMARK 465     ILE B  2011                                                      
REMARK 465     ASN B  2012                                                      
REMARK 465     VAL B  2013                                                      
REMARK 465     GLU B  2014                                                      
REMARK 465     THR B  2015                                                      
REMARK 465     VAL B  2016                                                      
REMARK 465     TYR B  2017                                                      
REMARK 465     ASP B  2018                                                      
REMARK 465     ILE B  2019                                                      
REMARK 465     MET B  2020                                                      
REMARK 465     ALA B  2021                                                      
REMARK 465     LEU B  2022                                                      
REMARK 465     GLU B  2023                                                      
REMARK 465     ASP B  2024                                                      
REMARK 465     GLU B  2025                                                      
REMARK 465     GLU B  2026                                                      
REMARK 465     ARG B  2027                                                      
REMARK 465     ASP B  2028                                                      
REMARK 465     GLU B  2029                                                      
REMARK 465     ILE B  2030                                                      
REMARK 465     LEU B  2031                                                      
REMARK 465     THR B  2032                                                      
REMARK 465     LEU B  2033                                                      
REMARK 465     THR B  2034                                                      
REMARK 465     ASP B  2035                                                      
REMARK 465     SER B  2036                                                      
REMARK 465     GLN B  2037                                                      
REMARK 465     LEU B  2038                                                      
REMARK 465     ALA B  2039                                                      
REMARK 465     GLN B  2040                                                      
REMARK 465     VAL B  2041                                                      
REMARK 465     ALA B  2042                                                      
REMARK 465     ALA B  2043                                                      
REMARK 465     PHE B  2044                                                      
REMARK 465     VAL B  2045                                                      
REMARK 465     ASN B  2046                                                      
REMARK 465     ASN B  2047                                                      
REMARK 465     TYR B  2048                                                      
REMARK 465     PRO B  2049                                                      
REMARK 465     ASN B  2050                                                      
REMARK 465     VAL B  2051                                                      
REMARK 465     GLU B  2052                                                      
REMARK 465     LEU B  2053                                                      
REMARK 465     THR B  2054                                                      
REMARK 465     TYR B  2055                                                      
REMARK 465     SER B  2056                                                      
REMARK 465     LEU B  2057                                                      
REMARK 465     ASN B  2058                                                      
REMARK 465     ASN B  2059                                                      
REMARK 465     SER B  2060                                                      
REMARK 465     ASP B  2061                                                      
REMARK 465     SER B  2062                                                      
REMARK 465     LEU B  2063                                                      
REMARK 465     ILE B  2064                                                      
REMARK 465     SER B  2065                                                      
REMARK 465     GLY B  2066                                                      
REMARK 465     VAL B  2067                                                      
REMARK 465     LYS B  2068                                                      
REMARK 465     GLN B  2069                                                      
REMARK 465     LYS B  2070                                                      
REMARK 465     ILE B  2071                                                      
REMARK 465     THR B  2072                                                      
REMARK 465     ILE B  2073                                                      
REMARK 465     GLN B  2074                                                      
REMARK 465     LEU B  2075                                                      
REMARK 465     THR B  2076                                                      
REMARK 465     ARG B  2077                                                      
REMARK 465     ASP B  2078                                                      
REMARK 465     VAL B  2079                                                      
REMARK 465     GLU B  2080                                                      
REMARK 465     PRO B  2081                                                      
REMARK 465     GLU B  2082                                                      
REMARK 465     ASN B  2083                                                      
REMARK 465     LEU B  2084                                                      
REMARK 465     GLN B  2085                                                      
REMARK 465     VAL B  2086                                                      
REMARK 465     THR B  2087                                                      
REMARK 465     SER B  2088                                                      
REMARK 465     GLU B  2089                                                      
REMARK 465     LYS B  2090                                                      
REMARK 465     TYR B  2091                                                      
REMARK 465     PRO B  2092                                                      
REMARK 465     PHE B  2093                                                      
REMARK 465     ASP B  2094                                                      
REMARK 465     LYS B  2095                                                      
REMARK 465     LEU B  2096                                                      
REMARK 465     GLU B  2097                                                      
REMARK 465     SER B  2098                                                      
REMARK 465     TRP B  2099                                                      
REMARK 465     TRP B  2100                                                      
REMARK 465     LEU B  2101                                                      
REMARK 465     VAL B  2102                                                      
REMARK 465     LEU B  2103                                                      
REMARK 465     GLY B  2104                                                      
REMARK 465     GLU B  2105                                                      
REMARK 465     VAL B  2106                                                      
REMARK 465     SER B  2107                                                      
REMARK 465     LYS B  2108                                                      
REMARK 465     LYS B  2109                                                      
REMARK 465     GLU B  2110                                                      
REMARK 465     LEU B  2111                                                      
REMARK 465     TYR B  2112                                                      
REMARK 465     ALA B  2113                                                      
REMARK 465     ILE B  2114                                                      
REMARK 465     LYS B  2115                                                      
REMARK 465     LYS B  2116                                                      
REMARK 465     VAL B  2117                                                      
REMARK 465     THR B  2118                                                      
REMARK 465     LEU B  2119                                                      
REMARK 465     ASN B  2120                                                      
REMARK 465     LYS B  2121                                                      
REMARK 465     GLU B  2122                                                      
REMARK 465     THR B  2123                                                      
REMARK 465     GLN B  2124                                                      
REMARK 465     GLN B  2125                                                      
REMARK 465     TYR B  2126                                                      
REMARK 465     GLU B  2127                                                      
REMARK 465     LEU B  2128                                                      
REMARK 465     GLU B  2129                                                      
REMARK 465     PHE B  2130                                                      
REMARK 465     ASP B  2131                                                      
REMARK 465     THR B  2132                                                      
REMARK 465     PRO B  2133                                                      
REMARK 465     THR B  2134                                                      
REMARK 465     SER B  2135                                                      
REMARK 465     GLY B  2136                                                      
REMARK 465     LYS B  2137                                                      
REMARK 465     HIS B  2138                                                      
REMARK 465     ASN B  2139                                                      
REMARK 465     LEU B  2140                                                      
REMARK 465     THR B  2141                                                      
REMARK 465     ILE B  2142                                                      
REMARK 465     TRP B  2143                                                      
REMARK 465     CYS B  2144                                                      
REMARK 465     VAL B  2145                                                      
REMARK 465     CYS B  2146                                                      
REMARK 465     ASP B  2147                                                      
REMARK 465     SER B  2148                                                      
REMARK 465     TYR B  2149                                                      
REMARK 465     LEU B  2150                                                      
REMARK 465     ASP B  2151                                                      
REMARK 465     ALA B  2152                                                      
REMARK 465     ASP B  2153                                                      
REMARK 465     LYS B  2154                                                      
REMARK 465     GLU B  2155                                                      
REMARK 465     LEU B  2156                                                      
REMARK 465     SER B  2157                                                      
REMARK 465     PHE B  2158                                                      
REMARK 465     GLU B  2159                                                      
REMARK 465     ILE B  2160                                                      
REMARK 465     ASN B  2161                                                      
REMARK 465     VAL B  2162                                                      
REMARK 465     LYS B  2163                                                      
REMARK 470                                                                      
REMARK 470 MISSING ATOM                                                         
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;           
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;          
REMARK 470 I=INSERTION CODE):                                                   
REMARK 470   M RES CSSEQI  ATOMS                                                
REMARK 470     GLN A2076    CG   CD   OE1  NE2                                  
REMARK 470     GLU H 252    CG   CD   OE1  OE2                                  
REMARK 470     ARG H 267    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU H 345    CG   CD1  CD2                                       
REMARK 470     LYS H 350    CG   CD   CE   NZ                                   
REMARK 470     GLU J 165    CG   CD   OE1  OE2                                  
REMARK 470     ARG J 166    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU J 167    CG   CD   OE1  OE2                                  
REMARK 470     LYS J 168    CG   CD   CE   NZ                                   
REMARK 470     GLU J 176    CG   CD   OE1  OE2                                  
REMARK 470     GLN J 180    CG   CD   OE1  NE2                                  
REMARK 470     LYS J 205    CG   CD   CE   NZ                                   
REMARK 470     ASP J 206    CG   OD1  OD2                                       
REMARK 470     ARG J 211    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP J 217    CG   OD1  OD2                                       
REMARK 470     GLU J 348    CG   CD   OE1  OE2                                  
REMARK 470     LYS J 351    CG   CD   CE   NZ                                   
REMARK 470     ASN J 412    CG   OD1  ND2                                       
REMARK 470     LYS J 420    CG   CD   CE   NZ                                   
REMARK 470     LYS J 438    CG   CD   CE   NZ                                   
REMARK 470     LEU J 441    CG   CD1  CD2                                       
REMARK 470     LYS J 446    CG   CD   CE   NZ                                   
REMARK 470     ARG J 447    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU J 449    CG   CD   OE1  OE2                                  
REMARK 470     ASN J 452    CG   OD1  ND2                                       
REMARK 470     GLU J 477    CG   CD   OE1  OE2                                  
REMARK 470     GLU J 479    CG   CD   OE1  OE2                                  
REMARK 470     GLU J 481    CG   CD   OE1  OE2                                  
REMARK 470     HIS J 494    CG   ND1  CD2  CE1  NE2                             
REMARK 470     TYR J 526    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     GLN J 572    CG   CD   OE1  NE2                                  
REMARK 470     LYS J 573    CG   CD   CE   NZ                                   
REMARK 470     ASN J 593    CG   OD1  ND2                                       
REMARK 470     PHE J 627    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     LYS J 628    CG   CD   CE   NZ                                   
REMARK 470     ILE J 629    CG1  CG2  CD1                                       
REMARK 470     GLU J 633    CG   CD   OE1  OE2                                  
REMARK 470     ARG J 634    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP J 727    CG   OD1  OD2                                       
REMARK 470     GLU F  49    CG   CD   OE1  OE2                                  
REMARK 470     ARG F  64    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU F  69    CG   CD   OE1  OE2                                  
REMARK 470     GLN F  72    CG   CD   OE1  NE2                                  
REMARK 470     ASP F  79    CG   OD1  OD2                                       
REMARK 470     PHE F  91    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ILE F  92    CG1  CG2  CD1                                       
REMARK 470     LYS F  93    CG   CD   CE   NZ                                   
REMARK 470     GLU F 126    CG   CD   OE1  OE2                                  
REMARK 470     LYS F 164    CG   CD   CE   NZ                                   
REMARK 470     LYS F 166    CG   CD   CE   NZ                                   
REMARK 470     GLU F 170    CG   CD   OE1  OE2                                  
REMARK 470     MET F 177    CG   SD   CE                                        
REMARK 470     LYS F 180    CG   CD   CE   NZ                                   
REMARK 470     THR F 195    OG1  CG2                                            
REMARK 470     GLU F 205    CG   CD   OE1  OE2                                  
REMARK 470     ASP F 213    CG   OD1  OD2                                       
REMARK 470     GLU F 236    CG   CD   OE1  OE2                                  
REMARK 470     GLU F 250    CG   CD   OE1  OE2                                  
REMARK 470     GLU F 282    CG   CD   OE1  OE2                                  
REMARK 470     ASP F 289    CG   OD1  OD2                                       
REMARK 470     LYS F 321    CG   CD   CE   NZ                                   
REMARK 470     GLU F 360    CG   CD   OE1  OE2                                  
REMARK 470     ASP F 361    CG   OD1  OD2                                       
REMARK 470     ASP G 170    CG   OD1  OD2                                       
REMARK 470     GLU G 176    CG   CD   OE1  OE2                                  
REMARK 470     LYS G 177    CG   CD   CE   NZ                                   
REMARK 470     GLU G 179    CG   CD   OE1  OE2                                  
REMARK 470     LYS G 183    CG   CD   CE   NZ                                   
REMARK 470     GLU G 227    CG   CD   OE1  OE2                                  
REMARK 470     GLU B 367    CG   CD   OE1  OE2                                  
REMARK 470     GLN B 388    CG   CD   OE1  NE2                                  
REMARK 470     TYR B 389    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ARG B 392    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU B 393    CG   CD   OE1  OE2                                  
REMARK 470     LYS B 398    CG   CD   CE   NZ                                   
REMARK 470     ARG B 399    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU B 400    CG   CD   OE1  OE2                                  
REMARK 470     GLN B 409    CG   CD   OE1  NE2                                  
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT                     
REMARK 500                                                                      
REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT.                            
REMARK 500                                                                      
REMARK 500  ATM1  RES C  SSEQI   ATM2  RES C  SSEQI           DISTANCE          
REMARK 500   O    ASP J   199     N    LEU J   201              2.14            
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES                                       
REMARK 500                                                                      
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES              
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE               
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                 
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)              
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999                        
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996                     
REMARK 500                                                                      
REMARK 500  M RES CSSEQI ATM1   ATM2   ATM3                                     
REMARK 500      A V  17   C2' -  C3' -  O3' ANGL. DEV. =  11.0 DEGREES          
REMARK 500    PRO A 980   C   -  N   -  CD  ANGL. DEV. = -15.3 DEGREES          
REMARK 500    LEU J 613   CA  -  CB  -  CG  ANGL. DEV. =  16.4 DEGREES          
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: TORSION ANGLES                                             
REMARK 500                                                                      
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:            
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)                    
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-           
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400            
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        PSI       PHI                                   
REMARK 500    UNK x   7       43.06     70.81                                   
REMARK 500    UNK x  18       78.24   -161.80                                   
REMARK 500    UNK x  47       80.75    -57.59                                   
REMARK 500    PRO A 771       57.74    -93.33                                   
REMARK 500    ILE A 774       44.68     36.13                                   
REMARK 500    ASN A 796       30.33     84.03                                   
REMARK 500    ALA A 838      -73.68    -87.77                                   
REMARK 500    HIS A 839      136.03   -175.24                                   
REMARK 500    PRO A 901      109.81    -44.13                                   
REMARK 500    THR A 904       59.82   -111.52                                   
REMARK 500    ASN A 907       54.46    -98.73                                   
REMARK 500    ASN A 930     -166.87    -70.54                                   
REMARK 500    ASN A 946       79.54   -110.29                                   
REMARK 500    MET A 972     -163.54    -78.67                                   
REMARK 500    GLU A 973       33.73   -143.07                                   
REMARK 500    GLN A 976      -36.48    -39.90                                   
REMARK 500    ASN A 977      119.61   -166.26                                   
REMARK 500    SER A 979      162.65    103.01                                   
REMARK 500    ASN A1034       40.38    -91.05                                   
REMARK 500    LEU A1049       76.30   -108.78                                   
REMARK 500    PHE A1092      135.30   -172.37                                   
REMARK 500    LYS A1093       79.29      4.24                                   
REMARK 500    MET A1095      102.68   -166.42                                   
REMARK 500    MET A1145       -2.42     69.10                                   
REMARK 500    ILE A1158       94.75    -67.58                                   
REMARK 500    LEU A1165     -119.83     58.76                                   
REMARK 500    GLU A1196       55.22   -103.50                                   
REMARK 500    LEU A1215       58.24    -91.70                                   
REMARK 500    SER A1252     -166.71   -121.72                                   
REMARK 500    PHE A1260      160.24    178.74                                   
REMARK 500    VAL A1278      -28.46     87.85                                   
REMARK 500    GLU A1283      106.25     74.39                                   
REMARK 500    ALA A1322       -1.04    100.62                                   
REMARK 500    THR A1326      128.11    -36.87                                   
REMARK 500    PHE A1346       30.18    -84.39                                   
REMARK 500    ALA A1386      -65.36    -23.98                                   
REMARK 500    ASP A1411       34.65    -82.67                                   
REMARK 500    ASN A1472       71.63     57.17                                   
REMARK 500    ASP A1485       56.28    -97.20                                   
REMARK 500    ASP A1498       40.96   -107.53                                   
REMARK 500    SER A1518      -56.31   -130.23                                   
REMARK 500    GLU A1520      -75.28    -80.13                                   
REMARK 500    PHE A1525       60.38   -110.58                                   
REMARK 500    LYS A1535       93.76    -60.12                                   
REMARK 500    GLN A1586       39.49    -95.72                                   
REMARK 500    LYS A1589       94.88    -65.24                                   
REMARK 500    PHE A1623       99.20    -52.26                                   
REMARK 500    PHE A1649       46.07   -101.50                                   
REMARK 500    GLU A1672       63.01   -115.82                                   
REMARK 500    SER A1696     -163.25   -110.57                                   
REMARK 500                                                                      
REMARK 500 THIS ENTRY HAS     190 RAMACHANDRAN OUTLIERS.                        
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: NON-CIS, NON-TRANS                                         
REMARK 500                                                                      
REMARK 500 THE FOLLOWING PEPTIDE BONDS DEVIATE SIGNIFICANTLY FROM BOTH          
REMARK 500 CIS AND TRANS CONFORMATION.  CIS BONDS, IF ANY, ARE LISTED           
REMARK 500 ON CISPEP RECORDS.  TRANS IS DEFINED AS 180 +/- 30 AND               
REMARK 500 CIS IS DEFINED AS 0 +/- 30 DEGREES.                                  
REMARK 500                                 MODEL     OMEGA                      
REMARK 500 SER A  979     PRO A  980                  -32.26                    
REMARK 500 VAL A 1278     VAL A 1279                 -147.77                    
REMARK 500 ASP A 1994     TRP A 1995                 -149.73                    
REMARK 500 SER F  154     ASP F  155                  -41.60                    
REMARK 500 ILE B  423     PRO B  424                  136.36                    
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 900                                                                      
REMARK 900 RELATED ENTRIES                                                      
REMARK 900 RELATED ID: EMD-8014   RELATED DB: EMDB                              
DBREF1 5GAP V    1    67  GB                   CP011083.1                       
DBREF2 5GAP V     807071957                      164495      164429             
DBREF1 5GAP W    1   112  GB                   CP011090.1                       
DBREF2 5GAP W     807071964                      348700      348811             
DBREF1 5GAP U    1   214  GB                   CP011085.1                       
DBREF2 5GAP U     807071959                      909079      908866             
DBREF  5GAP x    1   120  PDB    5GAP     5GAP             1    120             
DBREF  5GAP A    1  2413  UNP    P33334   PRP8_YEAST       1   2413             
DBREF  5GAP H    1   465  UNP    P20053   PRP4_YEAST       1    465             
DBREF  5GAP J    1   899  UNP    P19735   PRP6_YEAST       1    899             
DBREF  5GAP D    1   143  UNP    Q06819   DIB1_YEAST       1    143             
DBREF  5GAP F    1   494  UNP    P49704   PRP31_YEAST      1    494             
DBREF  5GAP G    1   469  UNP    Q03338   PRP3_YEAST       1    469             
DBREF  5GAP K    1   126  UNP    P39990   SNU13_YEAST      1    126             
DBREF  5GAP B    1  2163  UNP    P32639   BRR2_YEAST       1   2163             
SEQRES   1 V   67    A   U   C   C   U   U   A   U   G   C   A   C   G          
SEQRES   2 V   67    G   G   A   A   A   U   A   C   G   C   A   U   A          
SEQRES   3 V   67    U   C   A   G   U   G   A   G   G   A   U   U   C          
SEQRES   4 V   67    G   U   C   C   G   A   G   A   U   U   G   U   G          
SEQRES   5 V   67    U   U   U   U   U   G   C   U   G   G   U   U   G          
SEQRES   6 V   67    A   A                                                      
SEQRES   1 W  112    G   U   U   C   G   C   G   A   A   G   U   A   A          
SEQRES   2 W  112    C   C   C   U   U   C   G   U   G   G   A   C   A          
SEQRES   3 W  112    U   U   U   G   G   U   C   A   A   U   U   U   G          
SEQRES   4 W  112    A   A   A   C   A   A   U   A   C   A   G   A   G          
SEQRES   5 W  112    A   U   G   A   U   C   A   G   C   A   G   U   U          
SEQRES   6 W  112    C   C   C   C   U   G   C   A   U   A   A   G   G          
SEQRES   7 W  112    A   U   G   A   A   C   C   G   U   U   U   U   A          
SEQRES   8 W  112    C   A   A   A   G   A   G   A   U   U   U   A   U          
SEQRES   9 W  112    U   U   C   G   U   U   U   U                              
SEQRES   1 U  214    A   A   G   C   A   G   C   U   U   U   A   C   A          
SEQRES   2 U  214    G   A   U   C   A   A   U   G   G   C   G   G   A          
SEQRES   3 U  214    G   G   G   A   G   G   U   C   A   A   C   A   U          
SEQRES   4 U  214    C   A   A   G   A   A   C   U   G   U   G   G   G          
SEQRES   5 U  214    C   C   U   U   U   U   A   U   U   G   C   C   U          
SEQRES   6 U  214    A   U   A   G   A   A   C   U   U   A   U   A   A          
SEQRES   7 U  214    C   G   A   A   C   A   U   G   G   U   U   C   U          
SEQRES   8 U  214    U   G   C   C   U   U   U   U   A   C   C   A   G          
SEQRES   9 U  214    A   A   C   C   A   U   C   C   G   G   G   U   G          
SEQRES  10 U  214    U   U   G   U   C   U   C   C   A   U   A   G   A          
SEQRES  11 U  214    A   A   C   A   G   G   U   A   A   A   G   C   U          
SEQRES  12 U  214    G   U   C   C   G   U   U   A   C   U   G   U   G          
SEQRES  13 U  214    G   G   C   U   U   G   C   C   A   U   A   U   U          
SEQRES  14 U  214    U   U   U   U   G   G   A   A   C   U   U   U   U          
SEQRES  15 U  214    C   U   G   C   C   C   U   U   U   U   U   C   U          
SEQRES  16 U  214    C   A   A   U   G   A   G   U   A   A   G   G   A          
SEQRES  17 U  214    G   G   G   C   G   U                                      
SEQRES   1 x   82  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   2 x   82  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   3 x   82  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   4 x   82  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   5 x   82  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   6 x   82  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   7 x   82  UNK UNK UNK UNK                                              
SEQRES   1 A 2413  MET SER GLY LEU PRO PRO PRO PRO PRO GLY PHE GLU GLU          
SEQRES   2 A 2413  ASP SER ASP LEU ALA LEU PRO PRO PRO PRO PRO PRO PRO          
SEQRES   3 A 2413  PRO GLY TYR GLU ILE GLU GLU LEU ASP ASN PRO MET VAL          
SEQRES   4 A 2413  PRO SER SER VAL ASN GLU ASP THR PHE LEU PRO PRO PRO          
SEQRES   5 A 2413  PRO PRO PRO PRO SER ASN PHE GLU ILE ASN ALA GLU GLU          
SEQRES   6 A 2413  ILE VAL ASP PHE THR LEU PRO PRO PRO PRO PRO PRO PRO          
SEQRES   7 A 2413  GLY LEU ASP GLU LEU GLU THR LYS ALA GLU LYS LYS VAL          
SEQRES   8 A 2413  GLU LEU HIS GLY LYS ARG LYS LEU ASP ILE GLY LYS ASP          
SEQRES   9 A 2413  THR PHE VAL THR ARG LYS SER ARG LYS ARG ALA LYS LYS          
SEQRES  10 A 2413  MET THR LYS LYS ALA LYS ARG SER ASN LEU TYR THR PRO          
SEQRES  11 A 2413  LYS ALA GLU MET PRO PRO GLU HIS LEU ARG LYS ILE ILE          
SEQRES  12 A 2413  ASN THR HIS SER ASP MET ALA SER LYS MET TYR ASN THR          
SEQRES  13 A 2413  ASP LYS LYS ALA PHE LEU GLY ALA LEU LYS TYR LEU PRO          
SEQRES  14 A 2413  HIS ALA ILE LEU LYS LEU LEU GLU ASN MET PRO HIS PRO          
SEQRES  15 A 2413  TRP GLU GLN ALA LYS GLU VAL LYS VAL LEU TYR HIS THR          
SEQRES  16 A 2413  SER GLY ALA ILE THR PHE VAL ASN GLU THR PRO ARG VAL          
SEQRES  17 A 2413  ILE GLU PRO VAL TYR THR ALA GLN TRP SER ALA THR TRP          
SEQRES  18 A 2413  ILE ALA MET ARG ARG GLU LYS ARG ASP ARG THR HIS PHE          
SEQRES  19 A 2413  LYS ARG MET ARG PHE PRO PRO PHE ASP ASP ASP GLU PRO          
SEQRES  20 A 2413  PRO LEU SER TYR GLU GLN HIS ILE GLU ASN ILE GLU PRO          
SEQRES  21 A 2413  LEU ASP PRO ILE ASN LEU PRO LEU ASP SER GLN ASP ASP          
SEQRES  22 A 2413  GLU TYR VAL LYS ASP TRP LEU TYR ASP SER ARG PRO LEU          
SEQRES  23 A 2413  GLU GLU ASP SER LYS LYS VAL ASN GLY THR SER TYR LYS          
SEQRES  24 A 2413  LYS TRP SER PHE ASP LEU PRO GLU MET SER ASN LEU TYR          
SEQRES  25 A 2413  ARG LEU SER THR PRO LEU ARG ASP GLU VAL THR ASP LYS          
SEQRES  26 A 2413  ASN TYR TYR TYR LEU PHE ASP LYS LYS SER PHE PHE ASN          
SEQRES  27 A 2413  GLY LYS ALA LEU ASN ASN ALA ILE PRO GLY GLY PRO LYS          
SEQRES  28 A 2413  PHE GLU PRO LEU TYR PRO ARG GLU GLU GLU GLU ASP TYR          
SEQRES  29 A 2413  ASN GLU PHE ASN SER ILE ASP ARG VAL ILE PHE ARG VAL          
SEQRES  30 A 2413  PRO ILE ARG SER GLU TYR LYS VAL ALA PHE PRO HIS LEU          
SEQRES  31 A 2413  TYR ASN SER ARG PRO ARG SER VAL ARG ILE PRO TRP TYR          
SEQRES  32 A 2413  ASN ASN PRO VAL SER CYS ILE ILE GLN ASN ASP GLU GLU          
SEQRES  33 A 2413  TYR ASP THR PRO ALA LEU PHE PHE ASP PRO SER LEU ASN          
SEQRES  34 A 2413  PRO ILE PRO HIS PHE ILE ASP ASN ASN SER SER LEU ASN          
SEQRES  35 A 2413  VAL SER ASN THR LYS GLU ASN GLY ASP PHE THR LEU PRO          
SEQRES  36 A 2413  GLU ASP PHE ALA PRO LEU LEU ALA GLU GLU GLU GLU LEU          
SEQRES  37 A 2413  ILE LEU PRO ASN THR LYS ASP ALA MET SER LEU TYR HIS          
SEQRES  38 A 2413  SER PRO PHE PRO PHE ASN ARG THR LYS GLY LYS MET VAL          
SEQRES  39 A 2413  ARG ALA GLN ASP VAL ALA LEU ALA LYS LYS TRP PHE LEU          
SEQRES  40 A 2413  GLN HIS PRO ASP GLU GLU TYR PRO VAL LYS VAL LYS VAL          
SEQRES  41 A 2413  SER TYR GLN LYS LEU LEU LYS ASN TYR VAL LEU ASN GLU          
SEQRES  42 A 2413  LEU HIS PRO THR LEU PRO THR ASN HIS ASN LYS THR LYS          
SEQRES  43 A 2413  LEU LEU LYS SER LEU LYS ASN THR LYS TYR PHE GLN GLN          
SEQRES  44 A 2413  THR THR ILE ASP TRP VAL GLU ALA GLY LEU GLN LEU CYS          
SEQRES  45 A 2413  ARG GLN GLY HIS ASN MET LEU ASN LEU LEU ILE HIS ARG          
SEQRES  46 A 2413  LYS GLY LEU THR TYR LEU HIS LEU ASP TYR ASN PHE ASN          
SEQRES  47 A 2413  LEU LYS PRO THR LYS THR LEU THR THR LYS GLU ARG LYS          
SEQRES  48 A 2413  LYS SER ARG LEU GLY ASN SER PHE HIS LEU MET ARG GLU          
SEQRES  49 A 2413  LEU LEU LYS MET MET LYS LEU ILE VAL ASP THR HIS VAL          
SEQRES  50 A 2413  GLN PHE ARG LEU GLY ASN VAL ASP ALA PHE GLN LEU ALA          
SEQRES  51 A 2413  ASP GLY ILE HIS TYR ILE LEU ASN HIS ILE GLY GLN LEU          
SEQRES  52 A 2413  THR GLY ILE TYR ARG TYR LYS TYR LYS VAL MET HIS GLN          
SEQRES  53 A 2413  ILE ARG ALA CYS LYS ASP LEU LYS HIS ILE ILE TYR TYR          
SEQRES  54 A 2413  LYS PHE ASN LYS ASN LEU GLY LYS GLY PRO GLY CYS GLY          
SEQRES  55 A 2413  PHE TRP GLN PRO ALA TRP ARG VAL TRP LEU ASN PHE LEU          
SEQRES  56 A 2413  ARG GLY THR ILE PRO LEU LEU GLU ARG TYR ILE GLY ASN          
SEQRES  57 A 2413  LEU ILE THR ARG GLN PHE GLU GLY ARG SER ASN GLU ILE          
SEQRES  58 A 2413  VAL LYS THR THR THR LYS GLN ARG LEU ASP ALA TYR TYR          
SEQRES  59 A 2413  ASP LEU GLU LEU ARG ASN SER VAL MET ASP ASP ILE LEU          
SEQRES  60 A 2413  GLU MET MET PRO GLU SER ILE ARG GLN LYS LYS ALA ARG          
SEQRES  61 A 2413  THR ILE LEU GLN HIS LEU SER GLU ALA TRP ARG CYS TRP          
SEQRES  62 A 2413  LYS ALA ASN ILE PRO TRP ASP VAL PRO GLY MET PRO ALA          
SEQRES  63 A 2413  PRO ILE LYS LYS ILE ILE GLU ARG TYR ILE LYS SER LYS          
SEQRES  64 A 2413  ALA ASP ALA TRP VAL SER ALA ALA HIS TYR ASN ARG GLU          
SEQRES  65 A 2413  ARG ILE LYS ARG GLY ALA HIS VAL GLU LYS THR MET VAL          
SEQRES  66 A 2413  LYS LYS ASN LEU GLY ARG LEU THR ARG LEU TRP ILE LYS          
SEQRES  67 A 2413  ASN GLU GLN GLU ARG GLN ARG GLN ILE GLN LYS ASN GLY          
SEQRES  68 A 2413  PRO GLU ILE THR PRO GLU GLU ALA THR THR ILE PHE SER          
SEQRES  69 A 2413  VAL MET VAL GLU TRP LEU GLU SER ARG SER PHE SER PRO          
SEQRES  70 A 2413  ILE PRO PHE PRO PRO LEU THR TYR LYS ASN ASP THR LYS          
SEQRES  71 A 2413  ILE LEU VAL LEU ALA LEU GLU ASP LEU LYS ASP VAL TYR          
SEQRES  72 A 2413  ALA SER LYS VAL ARG LEU ASN ALA SER GLU ARG GLU GLU          
SEQRES  73 A 2413  LEU ALA LEU ILE GLU GLU ALA TYR ASP ASN PRO HIS ASP          
SEQRES  74 A 2413  THR LEU ASN ARG ILE LYS LYS TYR LEU LEU THR GLN ARG          
SEQRES  75 A 2413  VAL PHE LYS PRO VAL ASP ILE THR MET MET GLU ASN TYR          
SEQRES  76 A 2413  GLN ASN ILE SER PRO VAL TYR SER VAL ASP PRO LEU GLU          
SEQRES  77 A 2413  LYS ILE THR ASP ALA TYR LEU ASP GLN TYR LEU TRP TYR          
SEQRES  78 A 2413  GLU ALA ASP GLN ARG LYS LEU PHE PRO ASN TRP ILE LYS          
SEQRES  79 A 2413  PRO SER ASP SER GLU ILE PRO PRO LEU LEU VAL TYR LYS          
SEQRES  80 A 2413  TRP THR GLN GLY ILE ASN ASN LEU SER GLU ILE TRP ASP          
SEQRES  81 A 2413  VAL SER ARG GLY GLN SER ALA VAL LEU LEU GLU THR THR          
SEQRES  82 A 2413  LEU GLY GLU MET ALA GLU LYS ILE ASP PHE THR LEU LEU          
SEQRES  83 A 2413  ASN ARG LEU LEU ARG LEU ILE VAL ASP PRO ASN ILE ALA          
SEQRES  84 A 2413  ASP TYR ILE THR ALA LYS ASN ASN VAL VAL ILE ASN PHE          
SEQRES  85 A 2413  LYS ASP MET SER HIS VAL ASN LYS TYR GLY LEU ILE ARG          
SEQRES  86 A 2413  GLY LEU LYS PHE ALA SER PHE ILE PHE GLN TYR TYR GLY          
SEQRES  87 A 2413  LEU VAL ILE ASP LEU LEU LEU LEU GLY GLN GLU ARG ALA          
SEQRES  88 A 2413  THR ASP LEU ALA GLY PRO ALA ASN ASN PRO ASN GLU PHE          
SEQRES  89 A 2413  MET GLN PHE LYS SER LYS GLU VAL GLU LYS ALA HIS PRO          
SEQRES  90 A 2413  ILE ARG LEU TYR THR ARG TYR LEU ASP ARG ILE TYR MET          
SEQRES  91 A 2413  LEU PHE HIS PHE GLU GLU ASP GLU GLY GLU GLU LEU THR          
SEQRES  92 A 2413  ASP GLU TYR LEU ALA GLU ASN PRO ASP PRO ASN PHE GLU          
SEQRES  93 A 2413  ASN SER ILE GLY TYR ASN ASN ARG LYS CYS TRP PRO LYS          
SEQRES  94 A 2413  ASP SER ARG MET ARG LEU ILE ARG GLN ASP VAL ASN LEU          
SEQRES  95 A 2413  GLY ARG ALA VAL PHE TRP GLU ILE GLN SER ARG VAL PRO          
SEQRES  96 A 2413  THR SER LEU THR SER ILE LYS TRP GLU ASN ALA PHE VAL          
SEQRES  97 A 2413  SER VAL TYR SER LYS ASN ASN PRO ASN LEU LEU PHE SER          
SEQRES  98 A 2413  MET CYS GLY PHE GLU VAL ARG ILE LEU PRO ARG GLN ARG          
SEQRES  99 A 2413  MET GLU GLU VAL VAL SER ASN ASP GLU GLY VAL TRP ASP          
SEQRES 100 A 2413  LEU VAL ASP GLU ARG THR LYS GLN ARG THR ALA LYS ALA          
SEQRES 101 A 2413  TYR LEU LYS VAL SER GLU GLU GLU ILE LYS LYS PHE ASP          
SEQRES 102 A 2413  SER ARG ILE ARG GLY ILE LEU MET ALA SER GLY SER THR          
SEQRES 103 A 2413  THR PHE THR LYS VAL ALA ALA LYS TRP ASN THR SER LEU          
SEQRES 104 A 2413  ILE SER LEU PHE THR TYR PHE ARG GLU ALA ILE VAL ALA          
SEQRES 105 A 2413  THR GLU PRO LEU LEU ASP ILE LEU VAL LYS GLY GLU THR          
SEQRES 106 A 2413  ARG ILE GLN ASN ARG VAL LYS LEU GLY LEU ASN SER LYS          
SEQRES 107 A 2413  MET PRO THR ARG PHE PRO PRO ALA VAL PHE TYR THR PRO          
SEQRES 108 A 2413  LYS GLU LEU GLY GLY LEU GLY MET ILE SER ALA SER HIS          
SEQRES 109 A 2413  ILE LEU ILE PRO ALA SER ASP LEU SER TRP SER LYS GLN          
SEQRES 110 A 2413  THR ASP THR GLY ILE THR HIS PHE ARG ALA GLY MET THR          
SEQRES 111 A 2413  HIS GLU ASP GLU LYS LEU ILE PRO THR ILE PHE ARG TYR          
SEQRES 112 A 2413  ILE THR THR TRP GLU ASN GLU PHE LEU ASP SER GLN ARG          
SEQRES 113 A 2413  VAL TRP ALA GLU TYR ALA THR LYS ARG GLN GLU ALA ILE          
SEQRES 114 A 2413  GLN GLN ASN ARG ARG LEU ALA PHE GLU GLU LEU GLU GLY          
SEQRES 115 A 2413  SER TRP ASP ARG GLY ILE PRO ARG ILE SER THR LEU PHE          
SEQRES 116 A 2413  GLN ARG ASP ARG HIS THR LEU ALA TYR ASP ARG GLY HIS          
SEQRES 117 A 2413  ARG ILE ARG ARG GLU PHE LYS GLN TYR SER LEU GLU ARG          
SEQRES 118 A 2413  ASN SER PRO PHE TRP TRP THR ASN SER HIS HIS ASP GLY          
SEQRES 119 A 2413  LYS LEU TRP ASN LEU ASN ALA TYR ARG THR ASP VAL ILE          
SEQRES 120 A 2413  GLN ALA LEU GLY GLY ILE GLU THR ILE LEU GLU HIS THR          
SEQRES 121 A 2413  LEU PHE LYS GLY THR GLY PHE ASN SER TRP GLU GLY LEU          
SEQRES 122 A 2413  PHE TRP GLU LYS ALA SER GLY PHE GLU ASP SER MET GLN          
SEQRES 123 A 2413  PHE LYS LYS LEU THR HIS ALA GLN ARG THR GLY LEU SER          
SEQRES 124 A 2413  GLN ILE PRO ASN ARG ARG PHE THR LEU TRP TRP SER PRO          
SEQRES 125 A 2413  THR ILE ASN ARG ALA ASN VAL TYR VAL GLY PHE LEU VAL          
SEQRES 126 A 2413  GLN LEU ASP LEU THR GLY ILE PHE LEU HIS GLY LYS ILE          
SEQRES 127 A 2413  PRO THR LEU LYS ILE SER LEU ILE GLN ILE PHE ARG ALA          
SEQRES 128 A 2413  HIS LEU TRP GLN LYS ILE HIS GLU SER ILE VAL PHE ASP          
SEQRES 129 A 2413  ILE CYS GLN ILE LEU ASP GLY GLU LEU ASP VAL LEU GLN          
SEQRES 130 A 2413  ILE GLU SER VAL THR LYS GLU THR VAL HIS PRO ARG LYS          
SEQRES 131 A 2413  SER TYR LYS MET ASN SER SER ALA ALA ASP ILE THR MET          
SEQRES 132 A 2413  GLU SER VAL HIS GLU TRP GLU VAL SER LYS PRO SER LEU          
SEQRES 133 A 2413  LEU HIS GLU THR ASN ASP SER PHE LYS GLY LEU ILE THR          
SEQRES 134 A 2413  ASN LYS MET TRP PHE ASP VAL GLN LEU ARG TYR GLY ASP          
SEQRES 135 A 2413  TYR ASP SER HIS ASP ILE SER ARG TYR VAL ARG ALA LYS          
SEQRES 136 A 2413  PHE LEU ASP TYR THR THR ASP ASN VAL SER MET TYR PRO          
SEQRES 137 A 2413  SER PRO THR GLY VAL MET ILE GLY ILE ASP LEU ALA TYR          
SEQRES 138 A 2413  ASN MET TYR ASP ALA TYR GLY ASN TRP PHE ASN GLY LEU          
SEQRES 139 A 2413  LYS PRO LEU ILE GLN ASN SER MET ARG THR ILE MET LYS          
SEQRES 140 A 2413  ALA ASN PRO ALA LEU TYR VAL LEU ARG GLU ARG ILE ARG          
SEQRES 141 A 2413  LYS GLY LEU GLN ILE TYR GLN SER SER VAL GLN GLU PRO          
SEQRES 142 A 2413  PHE LEU ASN SER SER ASN TYR ALA GLU LEU PHE ASN ASN          
SEQRES 143 A 2413  ASP ILE LYS LEU PHE VAL ASP ASP THR ASN VAL TYR ARG          
SEQRES 144 A 2413  VAL THR VAL HIS LYS THR PHE GLU GLY ASN VAL ALA THR          
SEQRES 145 A 2413  LYS ALA ILE ASN GLY CYS ILE PHE THR LEU ASN PRO LYS          
SEQRES 146 A 2413  THR GLY HIS LEU PHE LEU LYS ILE ILE HIS THR SER VAL          
SEQRES 147 A 2413  TRP ALA GLY GLN LYS ARG LEU SER GLN LEU ALA LYS TRP          
SEQRES 148 A 2413  LYS THR ALA GLU GLU VAL SER ALA LEU VAL ARG SER LEU          
SEQRES 149 A 2413  PRO LYS GLU GLU GLN PRO LYS GLN ILE ILE VAL THR ARG          
SEQRES 150 A 2413  LYS ALA MET LEU ASP PRO LEU GLU VAL HIS MET LEU ASP          
SEQRES 151 A 2413  PHE PRO ASN ILE ALA ILE ARG PRO THR GLU LEU ARG LEU          
SEQRES 152 A 2413  PRO PHE SER ALA ALA MET SER ILE ASP LYS LEU SER ASP          
SEQRES 153 A 2413  VAL VAL MET LYS ALA THR GLU PRO GLN MET VAL LEU PHE          
SEQRES 154 A 2413  ASN ILE TYR ASP ASP TRP LEU ASP ARG ILE SER SER TYR          
SEQRES 155 A 2413  THR ALA PHE SER ARG LEU THR LEU LEU LEU ARG ALA LEU          
SEQRES 156 A 2413  LYS THR ASN GLU GLU SER ALA LYS MET ILE LEU LEU SER          
SEQRES 157 A 2413  ASP PRO THR ILE THR ILE LYS SER TYR HIS LEU TRP PRO          
SEQRES 158 A 2413  SER PHE THR ASP GLU GLN TRP ILE THR ILE GLU SER GLN          
SEQRES 159 A 2413  MET ARG ASP LEU ILE LEU THR GLU TYR GLY ARG LYS TYR          
SEQRES 160 A 2413  ASN VAL ASN ILE SER ALA LEU THR GLN THR GLU ILE LYS          
SEQRES 161 A 2413  ASP ILE ILE LEU GLY GLN ASN ILE LYS ALA PRO SER VAL          
SEQRES 162 A 2413  LYS ARG GLN LYS MET ALA GLU LEU GLU ALA ALA ARG SER          
SEQRES 163 A 2413  GLU LYS GLN ASN ASP GLU GLU ALA ALA GLY ALA SER THR          
SEQRES 164 A 2413  VAL MET LYS THR LYS THR ILE ASN ALA GLN GLY GLU GLU          
SEQRES 165 A 2413  ILE VAL VAL VAL ALA SER ALA ASP TYR GLU SER GLN THR          
SEQRES 166 A 2413  PHE SER SER LYS ASN GLU TRP ARG LYS SER ALA ILE ALA          
SEQRES 167 A 2413  ASN THR LEU LEU TYR LEU ARG LEU LYS ASN ILE TYR VAL          
SEQRES 168 A 2413  SER ALA ASP ASP PHE VAL GLU GLU GLN ASN VAL TYR VAL          
SEQRES 169 A 2413  LEU PRO LYS ASN LEU LEU LYS LYS PHE ILE GLU ILE SER          
SEQRES 170 A 2413  ASP VAL LYS ILE GLN VAL ALA ALA PHE ILE TYR GLY MET          
SEQRES 171 A 2413  SER ALA LYS ASP HIS PRO LYS VAL LYS GLU ILE LYS THR          
SEQRES 172 A 2413  VAL VAL LEU VAL PRO GLN LEU GLY HIS VAL GLY SER VAL          
SEQRES 173 A 2413  GLN ILE SER ASN ILE PRO ASP ILE GLY ASP LEU PRO ASP          
SEQRES 174 A 2413  THR GLU GLY LEU GLU LEU LEU GLY TRP ILE HIS THR GLN          
SEQRES 175 A 2413  THR GLU GLU LEU LYS PHE MET ALA ALA SER GLU VAL ALA          
SEQRES 176 A 2413  THR HIS SER LYS LEU PHE ALA ASP LYS LYS ARG ASP CYS          
SEQRES 177 A 2413  ILE ASP ILE SER ILE PHE SER THR PRO GLY SER VAL SER          
SEQRES 178 A 2413  LEU SER ALA TYR ASN LEU THR ASP GLU GLY TYR GLN TRP          
SEQRES 179 A 2413  GLY GLU GLU ASN LYS ASP ILE MET ASN VAL LEU SER GLU          
SEQRES 180 A 2413  GLY PHE GLU PRO THR PHE SER THR HIS ALA GLN LEU LEU          
SEQRES 181 A 2413  LEU SER ASP ARG ILE THR GLY ASN PHE ILE ILE PRO SER          
SEQRES 182 A 2413  GLY ASN VAL TRP ASN TYR THR PHE MET GLY THR ALA PHE          
SEQRES 183 A 2413  ASN GLN GLU GLY ASP TYR ASN PHE LYS TYR GLY ILE PRO          
SEQRES 184 A 2413  LEU GLU PHE TYR ASN GLU MET HIS ARG PRO VAL HIS PHE          
SEQRES 185 A 2413  LEU GLN PHE SER GLU LEU ALA GLY ASP GLU GLU LEU GLU          
SEQRES 186 A 2413  ALA GLU GLN ILE ASP VAL PHE SER                              
SEQRES   1 H  465  MET SER LYS TYR ILE ALA LEU GLU ASN LEU PRO VAL ASP          
SEQRES   2 H  465  LEU GLN HIS LYS GLY ALA THR GLN ASN GLU SER THR ALA          
SEQRES   3 H  465  ASP ILE LEU LYS GLN LEU PRO HIS GLU ARG LEU GLN ALA          
SEQRES   4 H  465  VAL LEU GLU LYS ILE PRO GLU GLU ASP LEU GLU VAL ARG          
SEQRES   5 H  465  ARG LEU LEU SER ILE LEU LYS LYS PRO GLU VAL VAL GLU          
SEQRES   6 H  465  ASN GLU ASP VAL GLN GLN ARG ARG ILE ARG LEU ALA GLU          
SEQRES   7 H  465  ILE LEU MET VAL ASP GLU ILE ASP LEU GLU ASN ILE ASN          
SEQRES   8 H  465  ASN MET GLU ASN ILE ASN GLY GLU GLU VAL ASP GLU GLU          
SEQRES   9 H  465  ASP ASP GLU ASP PHE PHE THR PRO ALA THR SER GLU LEU          
SEQRES  10 H  465  ILE PHE ALA ARG ARG PHE LEU ILE ASN TYR SER LEU GLU          
SEQRES  11 H  465  ARG SER ARG LYS ARG LEU GLN LYS GLU MET GLU ARG HIS          
SEQRES  12 H  465  GLN LYS PHE ASN THR ARG GLN GLU LEU LEU SER ARG ARG          
SEQRES  13 H  465  THR GLU LEU GLN ARG MET ALA ASN LEU GLU LEU ALA GLY          
SEQRES  14 H  465  SER GLN LEU VAL SER THR LYS PRO ILE SER ALA VAL SER          
SEQRES  15 H  465  LEU SER THR ASP ASP MET VAL VAL ALA THR GLY SER TRP          
SEQRES  16 H  465  ALA GLY ASP LEU GLN VAL LEU ASN SER GLN THR LEU GLN          
SEQRES  17 H  465  PRO LEU THR GLN LYS LEU ASP SER HIS VAL GLY LYS ILE          
SEQRES  18 H  465  GLY ALA ILE ASP TRP HIS PRO ASP SER ASN ASN GLN MET          
SEQRES  19 H  465  ILE SER CYS ALA GLU ASP GLY LEU ILE LYS ASN PHE GLN          
SEQRES  20 H  465  TYR SER ASN GLU GLU GLY GLY LEU ARG LEU LEU GLY ASP          
SEQRES  21 H  465  LEU VAL GLY HIS GLU ARG ARG ILE SER ASP VAL LYS TYR          
SEQRES  22 H  465  HIS PRO SER GLY LYS PHE ILE GLY SER ALA SER HIS ASP          
SEQRES  23 H  465  MET THR TRP ARG LEU TRP ASP ALA SER THR HIS GLN GLU          
SEQRES  24 H  465  LEU LEU LEU GLN GLU GLY HIS ASP LYS GLY VAL PHE SER          
SEQRES  25 H  465  LEU SER PHE GLN CYS ASP GLY SER LEU VAL CYS SER GLY          
SEQRES  26 H  465  GLY MET ASP SER LEU SER MET LEU TRP ASP ILE ARG SER          
SEQRES  27 H  465  GLY SER LYS VAL MET THR LEU ALA GLY HIS SER LYS PRO          
SEQRES  28 H  465  ILE TYR THR VAL ALA TRP SER PRO ASN GLY TYR GLN VAL          
SEQRES  29 H  465  ALA THR GLY GLY GLY ASP GLY ILE ILE ASN VAL TRP ASP          
SEQRES  30 H  465  ILE ARG LYS ARG ASP GLU GLY GLN LEU ASN GLN ILE LEU          
SEQRES  31 H  465  ALA HIS ARG ASN ILE VAL THR GLN VAL ARG PHE SER LYS          
SEQRES  32 H  465  GLU ASP GLY GLY LYS LYS LEU VAL SER CYS GLY TYR ASP          
SEQRES  33 H  465  ASN LEU ILE ASN VAL TYR SER SER ASP THR TRP LEU LYS          
SEQRES  34 H  465  MET GLY SER LEU ALA GLY HIS THR ASP LYS ILE ILE SER          
SEQRES  35 H  465  LEU ASP ILE SER ASN ASN SER HIS PHE LEU VAL SER GLY          
SEQRES  36 H  465  GLY TRP ASP ARG SER ILE LYS LEU TRP ASN                      
SEQRES   1 J  899  MET GLU ARG PRO SER PHE LEU ASP GLN GLU PRO PRO ALA          
SEQRES   2 J  899  GLY TYR VAL PRO GLY ILE GLY ARG GLY ALA THR GLY PHE          
SEQRES   3 J  899  SER THR LYS GLU LYS GLN VAL VAL SER ASN ASP ASP LYS          
SEQRES   4 J  899  GLY ARG ARG ILE PRO LYS ARG TYR ARG GLU ASN LEU ASN          
SEQRES   5 J  899  ASN HIS LEU GLN SER GLN PRO LYS ASP ASP GLU ASP ASP          
SEQRES   6 J  899  GLU ALA ALA ASN VAL PHE LYS THR LEU GLU LEU LYS LEU          
SEQRES   7 J  899  ALA GLN LYS LYS LYS LYS ARG ALA ASN GLU LYS ASP ASP          
SEQRES   8 J  899  ASP ASN SER VAL ASP SER SER ASN VAL LYS ARG GLN PHE          
SEQRES   9 J  899  ALA ASP LEU LYS GLU SER LEU ALA ALA VAL THR GLU SER          
SEQRES  10 J  899  GLU TRP MET ASP ILE PRO ASP ALA THR ASP PHE THR ARG          
SEQRES  11 J  899  ARG ASN LYS ARG ASN ARG ILE GLN GLU GLN LEU ASN ARG          
SEQRES  12 J  899  LYS THR TYR ALA ALA PRO ASP SER LEU ILE PRO GLY ASN          
SEQRES  13 J  899  VAL ASP LEU ASN LYS LEU THR GLU GLU ARG GLU LYS LEU          
SEQRES  14 J  899  LEU GLN SER GLN ILE ASP GLU ASN LEU ALA GLN LEU THR          
SEQRES  15 J  899  LYS ASN ALA SER ASN PRO ILE GLN VAL ASN LYS PRO ASN          
SEQRES  16 J  899  ALA ALA THR ASP ALA LEU SER TYR LEU LYS ASP LEU GLU          
SEQRES  17 J  899  ASN ASP ARG VAL ASN SER LEU SER ASP ALA THR LEU GLU          
SEQRES  18 J  899  ASP LEU GLN LYS MET ARG THR ILE LEU LYS SER TYR ARG          
SEQRES  19 J  899  LYS ALA ASP PRO THR ASN PRO GLN GLY TRP ILE ALA SER          
SEQRES  20 J  899  ALA ARG LEU GLU GLU LYS ALA ARG LYS PHE SER VAL ALA          
SEQRES  21 J  899  LYS LYS ILE ILE GLU ASN GLY CYS GLN GLU CYS PRO ARG          
SEQRES  22 J  899  SER SER ASP ILE TRP LEU GLU ASN ILE ARG LEU HIS GLU          
SEQRES  23 J  899  SER ASP VAL HIS TYR CYS LYS THR LEU VAL ALA THR ALA          
SEQRES  24 J  899  ILE ASN PHE ASN PRO THR SER PRO LEU LEU TRP PHE LYS          
SEQRES  25 J  899  ALA ILE ASP LEU GLU SER THR THR VAL ASN LYS TYR ARG          
SEQRES  26 J  899  VAL VAL ARG LYS ALA LEU GLN GLU ILE PRO ARG ASP GLU          
SEQRES  27 J  899  GLY LEU TRP LYS LEU ALA VAL SER PHE GLU ALA ASP LYS          
SEQRES  28 J  899  ALA GLN VAL ILE LYS MET LEU GLU LYS ALA THR GLN PHE          
SEQRES  29 J  899  ILE PRO GLN SER MET ASP LEU LEU THR ALA TYR THR ASN          
SEQRES  30 J  899  LEU GLN SER TYR HIS ASN ALA LYS MET THR LEU ASN SER          
SEQRES  31 J  899  PHE ARG LYS ILE LEU PRO GLN GLU PRO GLU ILE TRP ILE          
SEQRES  32 J  899  ILE SER THR LEU LEU GLU GLU ARG ASN ASN PRO ASP ILE          
SEQRES  33 J  899  PRO VAL ASP LYS LEU VAL SER LEU LEU LYS GLU GLY LEU          
SEQRES  34 J  899  LEU GLU LEU SER LYS ASN GLY TYR LYS ALA THR LEU SER          
SEQRES  35 J  899  ALA TRP LEU LYS ARG ALA GLU ALA LEU ASN ASP ALA PRO          
SEQRES  36 J  899  ASN SER ASN LEU THR CYS GLN ALA ILE VAL TYR ALA ILE          
SEQRES  37 J  899  LEU GLU TRP LEU ARG GLU SER GLY GLU TYR GLU SER GLU          
SEQRES  38 J  899  LEU ASN ASN VAL ASP GLN ILE LEU GLU LYS MET PRO HIS          
SEQRES  39 J  899  SER LYS VAL GLN ILE ALA VAL LEU LYS LYS LEU ILE GLN          
SEQRES  40 J  899  TRP ASP PRO CYS ASP THR VAL LEU TRP SER ARG LEU LYS          
SEQRES  41 J  899  MET ALA THR GLU SER TYR HIS LYS ILE GLU GLU LEU LEU          
SEQRES  42 J  899  ALA PHE PHE GLN GLU LEU LEU PHE GLN THR LYS ASN SER          
SEQRES  43 J  899  ASP ASP ILE ARG ALA ASN MET ARG GLU LYS SER PRO GLY          
SEQRES  44 J  899  LEU LEU MET MET TYR VAL SER GLU TYR TRP LYS ALA GLN          
SEQRES  45 J  899  LYS GLY ASP THR ARG GLN THR LEU VAL LEU ILE ASP GLN          
SEQRES  46 J  899  ILE ILE ASP PHE ALA PRO HIS ASN LEU ASP LEU ARG PHE          
SEQRES  47 J  899  PHE LYS ILE LYS LEU LEU GLY ARG SER LEU GLN LEU ASP          
SEQRES  48 J  899  GLU LEU ARG ASP PHE PHE GLN GLN THR PHE SER SER LEU          
SEQRES  49 J  899  GLU ASP PHE LYS ILE SER GLY THR GLU ARG LEU TYR TYR          
SEQRES  50 J  899  LYS TYR VAL ASN PHE LEU ARG TYR GLN ASP LEU ASN GLU          
SEQRES  51 J  899  GLU ALA ILE LYS PHE LEU ASN GLU ARG CYS LEU LYS SER          
SEQRES  52 J  899  PHE PRO ILE CYS HIS LYS PHE PHE LEU GLN LEU GLY GLN          
SEQRES  53 J  899  ILE TYR HIS SER MET GLY ASN ILE GLU MET SER ARG GLU          
SEQRES  54 J  899  THR TYR LEU SER GLY THR ARG LEU VAL PRO ASN CYS PRO          
SEQRES  55 J  899  LEU LEU TRP VAL SER LEU SER LYS ILE ASP GLU ILE ASP          
SEQRES  56 J  899  LEU LYS ASN PRO VAL ARG ALA ARG SER ILE LEU ASP ARG          
SEQRES  57 J  899  GLY LEU LEU LYS ASN PRO ASP ASP VAL LEU PHE TYR ILE          
SEQRES  58 J  899  ALA LYS ILE GLN MET GLU ILE ARG LEU GLY ASN LEU ASP          
SEQRES  59 J  899  GLN ALA GLU LEU LEU VAL THR GLN ALA LEU GLN LYS PHE          
SEQRES  60 J  899  PRO SER ASN ALA LEU LEU TRP VAL GLU GLN ILE LYS LEU          
SEQRES  61 J  899  PHE LYS HIS GLY ASN LYS SER SER LEU LYS LYS THR ILE          
SEQRES  62 J  899  PHE GLN ASP ALA LEU ARG ARG THR GLN ASN ASP HIS ARG          
SEQRES  63 J  899  VAL LEU LEU GLU ILE GLY VAL SER PHE TYR ALA GLU ALA          
SEQRES  64 J  899  GLN TYR GLU THR SER LEU LYS TRP LEU GLU ARG ALA LEU          
SEQRES  65 J  899  LYS LYS CYS SER ARG TYR GLY ASP THR TRP VAL TRP LEU          
SEQRES  66 J  899  PHE ARG THR TYR ALA ARG LEU GLY LYS ASP THR VAL ASP          
SEQRES  67 J  899  LEU TYR ASN MET PHE ASP GLN CYS GLU PRO THR TYR GLY          
SEQRES  68 J  899  PRO GLU TRP ILE ALA ALA SER LYS ASN VAL LYS MET GLN          
SEQRES  69 J  899  TYR CYS THR PRO ARG GLU ILE LEU LEU ARG LEU MET ASN          
SEQRES  70 J  899  ASP LYS                                                      
SEQRES   1 D  143  MET ALA SER VAL LEU LEU PRO GLN LEU ARG THR GLY TRP          
SEQRES   2 D  143  HIS VAL ASP GLN ALA ILE VAL THR GLU THR LYS ARG LEU          
SEQRES   3 D  143  VAL VAL ILE ARG PHE GLY ARG LYS ASN ASP ARG GLN CYS          
SEQRES   4 D  143  MET ILE MET ASP GLU LEU LEU SER SER ILE ALA GLU ARG          
SEQRES   5 D  143  VAL ARG ASN PHE ALA VAL ILE TYR LEU CYS ASP ILE ASP          
SEQRES   6 D  143  GLU VAL SER ASP PHE ASP GLU MET TYR GLU LEU THR ASP          
SEQRES   7 D  143  PRO MET THR VAL MET PHE PHE TYR HIS ASN LYS HIS MET          
SEQRES   8 D  143  MET CYS ASP PHE GLY THR GLY ASN ASN ASN LYS LEU ASN          
SEQRES   9 D  143  PHE ILE VAL ASP ASP LYS GLN GLU MET ILE ASP ILE LEU          
SEQRES  10 D  143  GLU THR ILE PHE ARG GLY ALA ARG LYS ASN LYS GLY LEU          
SEQRES  11 D  143  VAL VAL SER PRO TYR ASP TYR ASN HIS LYS ARG VAL SER          
SEQRES   1 F  494  MET SER SER GLU GLU ASP TYR PHE ASP GLU LEU GLU TYR          
SEQRES   2 F  494  ASP LEU ALA ASP GLU VAL ASN GLU GLU LYS GLU ASP ILE          
SEQRES   3 F  494  GLN THR LYS LYS LEU THR THR VAL ASN CYS GLN THR GLU          
SEQRES   4 F  494  LYS PHE ASN PRO PHE GLU ILE LEU PRO GLU SER ILE GLU          
SEQRES   5 F  494  LEU PHE ARG THR LEU ALA LEU ILE SER PRO ASP ARG LEU          
SEQRES   6 F  494  SER LEU SER GLU THR ALA GLN ILE LEU PRO LYS ILE VAL          
SEQRES   7 F  494  ASP LEU LYS ARG ILE LEU GLN GLN GLN GLU ILE ASP PHE          
SEQRES   8 F  494  ILE LYS LEU LEU PRO PHE PHE ASN GLU ILE ILE PRO LEU          
SEQRES   9 F  494  ILE LYS SER ASN ILE LYS LEU MET HIS ASN PHE LEU ILE          
SEQRES  10 F  494  SER LEU TYR SER ARG ARG PHE PRO GLU LEU SER SER LEU          
SEQRES  11 F  494  ILE PRO SER PRO LEU GLN TYR SER LYS VAL ILE SER ILE          
SEQRES  12 F  494  LEU GLU ASN GLU ASN TYR SER LYS ASN GLU SER ASP GLU          
SEQRES  13 F  494  LEU PHE PHE HIS LEU GLU ASN LYS ALA LYS LEU THR ARG          
SEQRES  14 F  494  GLU GLN ILE LEU VAL LEU THR MET SER MET LYS THR SER          
SEQRES  15 F  494  PHE LYS ASN LYS GLU PRO LEU ASP ILE LYS THR ARG THR          
SEQRES  16 F  494  GLN ILE LEU GLU ALA ASN SER ILE LEU GLU ASN LEU TRP          
SEQRES  17 F  494  LYS LEU GLN GLU ASP ILE GLY GLN TYR ILE ALA SER LYS          
SEQRES  18 F  494  ILE SER ILE ILE ALA PRO ASN VAL CYS PHE LEU VAL GLY          
SEQRES  19 F  494  PRO GLU ILE ALA ALA GLN LEU ILE ALA HIS ALA GLY GLY          
SEQRES  20 F  494  VAL LEU GLU PHE SER ARG ILE PRO SER CYS ASN ILE ALA          
SEQRES  21 F  494  SER ILE GLY LYS ASN LYS HIS LEU SER HIS GLU LEU HIS          
SEQRES  22 F  494  THR LEU GLU SER GLY VAL ARG GLN GLU GLY TYR LEU PHE          
SEQRES  23 F  494  ALA SER ASP MET ILE GLN LYS PHE PRO VAL SER VAL HIS          
SEQRES  24 F  494  LYS GLN MET LEU ARG MET LEU CYS ALA LYS VAL SER LEU          
SEQRES  25 F  494  ALA ALA ARG VAL ASP ALA GLY GLN LYS ASN GLY ASP ARG          
SEQRES  26 F  494  ASN THR VAL LEU ALA HIS LYS TRP LYS ALA GLU LEU SER          
SEQRES  27 F  494  LYS LYS ALA ARG LYS LEU SER GLU ALA PRO SER ILE SER          
SEQRES  28 F  494  GLU THR LYS ALA LEU PRO ILE PRO GLU ASP GLN PRO LYS          
SEQRES  29 F  494  LYS LYS ARG ALA GLY ARG LYS PHE ARG LYS TYR LYS GLU          
SEQRES  30 F  494  LYS PHE ARG LEU SER HIS VAL ARG GLN LEU GLN ASN ARG          
SEQRES  31 F  494  MET GLU PHE GLY LYS GLN GLU GLN THR VAL LEU ASP SER          
SEQRES  32 F  494  TYR GLY GLU GLU VAL GLY LEU GLY MET SER ASN THR SER          
SEQRES  33 F  494  LEU GLN GLN ALA VAL GLY ALA THR SER GLY SER ARG ARG          
SEQRES  34 F  494  SER ALA GLY ASN GLN ALA LYS LEU THR LYS VAL MET LYS          
SEQRES  35 F  494  HIS ARG ILE SER GLU ALA ASN GLN GLN ALA ASP GLU PHE          
SEQRES  36 F  494  LEU ILE SER LEU GLY HIS ASN THR GLU GLN PRO ASN LEU          
SEQRES  37 F  494  SER PRO GLU MET VAL GLN MET HIS LYS LYS GLN HIS THR          
SEQRES  38 F  494  ASN PRO GLU GLU GLU THR ASN TRP PHE SER GLY HIS GLY          
SEQRES   1 G  469  MET PRO PRO ARG ASN THR TYR GLU LYS GLY ASN PRO LYS          
SEQRES   2 G  469  ARG GLN ASN SER PRO TYR TYR LYS PRO SER PHE LEU ARG          
SEQRES   3 G  469  ARG GLU GLU THR THR ASN ASP GLU GLU LYS PHE GLN GLY          
SEQRES   4 G  469  HIS GLY LEU LYS THR GLU LEU HIS SER ALA LEU LYS SER          
SEQRES   5 G  469  SER ASN LEU ASN LEU ILE ARG ARG THR TYR GLN THR GLY          
SEQRES   6 G  469  GLU ASN PRO TYR LEU SER ASP PRO HIS ASP ARG GLY SER          
SEQRES   7 G  469  SER SER ARG PHE ASN ARG ARG TYR GLU ARG GLY LEU LYS          
SEQRES   8 G  469  PHE TYR GLN LYS GLY GLU ILE SER LYS ARG ILE ALA GLN          
SEQRES   9 G  469  GLU ARG THR LEU GLN LYS GLN GLN GLU GLU GLU GLU LEU          
SEQRES  10 G  469  LYS ARG LYS LEU LYS GLN GLU GLU ASP GLU LYS ASP LYS          
SEQRES  11 G  469  ARG LYS LEU ILE GLU SER GLY ASP LEU PRO ASN LEU GLU          
SEQRES  12 G  469  LEU HIS GLU ASP LYS PHE LEU LEU ASP LEU SER LYS PHE          
SEQRES  13 G  469  LYS ILE TYR TYR ASP ASN ASN HIS GLY TYR GLU TRP TRP          
SEQRES  14 G  469  ASP THR ALA TYR LEU ASP GLU LYS GLY GLU LEU MET GLU          
SEQRES  15 G  469  LYS TYR ASP MET ASN GLY THR SER PRO ALA GLU GLU LYS          
SEQRES  16 G  469  LEU ALA GLU ASP ILE ASP GLU VAL ASP ASP ASP ASP ASP          
SEQRES  17 G  469  ASP GLU HIS PRO SER ILE ARG TYR VAL ALA HIS PRO LEU          
SEQRES  18 G  469  PRO GLU LYS ILE ASN GLU ALA LYS VAL SER ILE LYS ALA          
SEQRES  19 G  469  TYR LEU THR GLN HIS GLU ARG LYS ARG LEU ARG ARG ASN          
SEQRES  20 G  469  ARG ARG LYS MET ALA ARG GLU ALA ARG GLU ILE LYS ILE          
SEQRES  21 G  469  LYS LEU GLY LEU LEU PRO LYS PRO GLU PRO LYS VAL LYS          
SEQRES  22 G  469  LEU SER ASN MET MET SER VAL PHE GLU ASN ASP GLN ASN          
SEQRES  23 G  469  ILE THR ASP PRO THR ALA TRP GLU LYS VAL VAL LYS ASP          
SEQRES  24 G  469  GLN VAL ASP LEU ARG LYS ARG LYS HIS LEU GLU GLU ASN          
SEQRES  25 G  469  GLU ARG ARG HIS GLU ASP ALA ILE LYS ARG ARG LYS GLU          
SEQRES  26 G  469  ALA VAL ASN MET ASN VAL GLU LYS PRO THR VAL TYR HIS          
SEQRES  27 G  469  CYS LYS VAL PHE GLN PHE LYS ASN LEU GLN ASN PRO LYS          
SEQRES  28 G  469  ILE ARG PHE LYS LEU LYS MET ASN SER LYS GLU LEU SER          
SEQRES  29 G  469  LEU LYS GLY LEU CYS LEU ARG ILE ARG ASP ASP GLY PRO          
SEQRES  30 G  469  GLY ILE ILE ILE VAL VAL GLY ASN GLU LYS SER CYS LYS          
SEQRES  31 G  469  PHE TYR GLU ASN LEU VAL MET LYS ARG ILE LYS TRP ASN          
SEQRES  32 G  469  GLU ASP PHE GLU LEU HIS THR ASN THR GLY ASP ILE LYS          
SEQRES  33 G  469  MET ASP MET HIS ASN ASN SER ILE SER LYS THR TRP GLU          
SEQRES  34 G  469  GLY TYR LEU GLN ASP CYS LYS PHE LYS GLY TRP PHE MET          
SEQRES  35 G  469  LYS VAL CYS ASN ASP GLN ASP SER LEU LEU ARG THR LEU          
SEQRES  36 G  469  GLY GLN PHE ASP SER GLU HIS PHE TYR SER PRO VAL GLN          
SEQRES  37 G  469  THR                                                          
SEQRES   1 K  126  MET SER ALA PRO ASN PRO LYS ALA PHE PRO LEU ALA ASP          
SEQRES   2 K  126  ALA ALA LEU THR GLN GLN ILE LEU ASP VAL VAL GLN GLN          
SEQRES   3 K  126  ALA ALA ASN LEU ARG GLN LEU LYS LYS GLY ALA ASN GLU          
SEQRES   4 K  126  ALA THR LYS THR LEU ASN ARG GLY ILE SER GLU PHE ILE          
SEQRES   5 K  126  ILE MET ALA ALA ASP CYS GLU PRO ILE GLU ILE LEU LEU          
SEQRES   6 K  126  HIS LEU PRO LEU LEU CYS GLU ASP LYS ASN VAL PRO TYR          
SEQRES   7 K  126  VAL PHE VAL PRO SER ARG VAL ALA LEU GLY ARG ALA CYS          
SEQRES   8 K  126  GLY VAL SER ARG PRO VAL ILE ALA ALA SER ILE THR THR          
SEQRES   9 K  126  ASN ASP ALA SER ALA ILE LYS THR GLN ILE TYR ALA VAL          
SEQRES  10 K  126  LYS ASP LYS ILE GLU THR LEU LEU ILE                          
SEQRES   1 B 2163  MET THR GLU HIS GLU THR LYS ASP LYS ALA LYS LYS ILE          
SEQRES   2 B 2163  ARG GLU ILE TYR ARG TYR ASP GLU MET SER ASN LYS VAL          
SEQRES   3 B 2163  LEU LYS VAL ASP LYS ARG PHE MET ASN THR SER GLN ASN          
SEQRES   4 B 2163  PRO GLN ARG ASP ALA GLU ILE SER GLN PRO LYS SER MET          
SEQRES   5 B 2163  SER GLY ARG ILE SER ALA LYS ASP MET GLY GLN GLY LEU          
SEQRES   6 B 2163  CYS ASN ASN ILE ASN LYS GLY LEU LYS GLU ASN ASP VAL          
SEQRES   7 B 2163  ALA VAL GLU LYS THR GLY LYS SER ALA SER LEU LYS LYS          
SEQRES   8 B 2163  ILE GLN GLN HIS ASN THR ILE LEU ASN SER SER SER ASP          
SEQRES   9 B 2163  PHE ARG LEU HIS TYR TYR PRO LYS ASP PRO SER ASN VAL          
SEQRES  10 B 2163  GLU THR TYR GLU GLN ILE LEU GLN TRP VAL THR GLU VAL          
SEQRES  11 B 2163  LEU GLY ASN ASP ILE PRO HIS ASP LEU ILE ILE GLY THR          
SEQRES  12 B 2163  ALA ASP ILE PHE ILE ARG GLN LEU LYS GLU ASN GLU GLU          
SEQRES  13 B 2163  ASN GLU ASP GLY ASN ILE GLU GLU ARG LYS GLU LYS ILE          
SEQRES  14 B 2163  GLN HIS GLU LEU GLY ILE ASN ILE ASP SER LEU LYS PHE          
SEQRES  15 B 2163  ASN GLU LEU VAL LYS LEU MET LYS ASN ILE THR ASP TYR          
SEQRES  16 B 2163  GLU THR HIS PRO ASP ASN SER ASN LYS GLN ALA VAL ALA          
SEQRES  17 B 2163  ILE LEU ALA ASP ASP GLU LYS SER ASP GLU GLU GLU VAL          
SEQRES  18 B 2163  THR GLU MET SER ASN ASN ALA ASN VAL LEU GLY GLY GLU          
SEQRES  19 B 2163  ILE ASN ASP ASN GLU ASP ASP ASP GLU GLU TYR ASP TYR          
SEQRES  20 B 2163  ASN ASP VAL GLU VAL ASN SER LYS LYS LYS ASN LYS ARG          
SEQRES  21 B 2163  ALA LEU PRO ASN ILE GLU ASN ASP ILE ILE LYS LEU SER          
SEQRES  22 B 2163  ASP SER LYS THR SER ASN ILE GLU SER VAL PRO ILE TYR          
SEQRES  23 B 2163  SER ILE ASP GLU PHE PHE LEU GLN ARG LYS LEU ARG SER          
SEQRES  24 B 2163  GLU LEU GLY TYR LYS ASP THR SER VAL ILE GLN ASP LEU          
SEQRES  25 B 2163  SER GLU LYS ILE LEU ASN ASP ILE GLU THR LEU GLU HIS          
SEQRES  26 B 2163  ASN PRO VAL ALA LEU GLU GLN LYS LEU VAL ASP LEU LEU          
SEQRES  27 B 2163  LYS PHE GLU ASN ILE SER LEU ALA GLU PHE ILE LEU LYS          
SEQRES  28 B 2163  ASN ARG SER THR ILE PHE TRP GLY ILE ARG LEU ALA LYS          
SEQRES  29 B 2163  SER THR GLU ASN GLU ILE PRO ASN LEU ILE GLU LYS MET          
SEQRES  30 B 2163  VAL ALA LYS GLY LEU ASN ASP LEU VAL GLU GLN TYR LYS          
SEQRES  31 B 2163  PHE ARG GLU THR THR HIS SER LYS ARG GLU LEU ASP SER          
SEQRES  32 B 2163  GLY ASP ASP GLN PRO GLN SER SER GLU ALA LYS ARG THR          
SEQRES  33 B 2163  LYS PHE SER ASN PRO ALA ILE PRO PRO VAL ILE ASP LEU          
SEQRES  34 B 2163  GLU LYS ILE LYS PHE ASP GLU SER SER LYS LEU MET THR          
SEQRES  35 B 2163  VAL THR LYS VAL SER LEU PRO GLU GLY SER PHE LYS ARG          
SEQRES  36 B 2163  VAL LYS PRO GLN TYR ASP GLU ILE HIS ILE PRO ALA PRO          
SEQRES  37 B 2163  SER LYS PRO VAL ILE ASP TYR GLU LEU LYS GLU ILE THR          
SEQRES  38 B 2163  SER LEU PRO ASP TRP CYS GLN GLU ALA PHE PRO SER SER          
SEQRES  39 B 2163  GLU THR THR SER LEU ASN PRO ILE GLN SER LYS VAL PHE          
SEQRES  40 B 2163  HIS ALA ALA PHE GLU GLY ASP SER ASN MET LEU ILE CYS          
SEQRES  41 B 2163  ALA PRO THR GLY SER GLY LYS THR ASN ILE ALA LEU LEU          
SEQRES  42 B 2163  THR VAL LEU LYS ALA LEU SER HIS HIS TYR ASN PRO LYS          
SEQRES  43 B 2163  THR LYS LYS LEU ASN LEU SER ALA PHE LYS ILE VAL TYR          
SEQRES  44 B 2163  ILE ALA PRO LEU LYS ALA LEU VAL GLN GLU GLN VAL ARG          
SEQRES  45 B 2163  GLU PHE GLN ARG ARG LEU ALA PHE LEU GLY ILE LYS VAL          
SEQRES  46 B 2163  ALA GLU LEU THR GLY ASP SER ARG LEU SER ARG LYS GLN          
SEQRES  47 B 2163  ILE ASP GLU THR GLN VAL LEU VAL SER THR PRO GLU LYS          
SEQRES  48 B 2163  TRP ASP ILE THR THR ARG ASN SER ASN ASN LEU ALA ILE          
SEQRES  49 B 2163  VAL GLU LEU VAL ARG LEU LEU ILE ILE ASP GLU ILE HIS          
SEQRES  50 B 2163  LEU LEU HIS ASP ASP ARG GLY PRO VAL LEU GLU SER ILE          
SEQRES  51 B 2163  VAL ALA ARG THR PHE TRP ALA SER LYS TYR GLY GLN GLU          
SEQRES  52 B 2163  TYR PRO ARG ILE ILE GLY LEU SER ALA THR LEU PRO ASN          
SEQRES  53 B 2163  TYR GLU ASP VAL GLY ARG PHE LEU ARG VAL PRO LYS GLU          
SEQRES  54 B 2163  GLY LEU PHE TYR PHE ASP SER SER PHE ARG PRO CYS PRO          
SEQRES  55 B 2163  LEU SER GLN GLN PHE CYS GLY ILE LYS GLU ARG ASN SER          
SEQRES  56 B 2163  LEU LYS LYS LEU LYS ALA MET ASN ASP ALA CYS TYR GLU          
SEQRES  57 B 2163  LYS VAL LEU GLU SER ILE ASN GLU GLY ASN GLN ILE ILE          
SEQRES  58 B 2163  VAL PHE VAL HIS SER ARG LYS GLU THR SER ARG THR ALA          
SEQRES  59 B 2163  THR TRP LEU LYS ASN LYS PHE ALA GLU GLU ASN ILE THR          
SEQRES  60 B 2163  HIS LYS LEU THR LYS ASN ASP ALA GLY SER LYS GLN ILE          
SEQRES  61 B 2163  LEU LYS THR GLU ALA ALA ASN VAL LEU ASP PRO SER LEU          
SEQRES  62 B 2163  ARG LYS LEU ILE GLU SER GLY ILE GLY THR HIS HIS ALA          
SEQRES  63 B 2163  GLY LEU THR ARG SER ASP ARG SER LEU SER GLU ASP LEU          
SEQRES  64 B 2163  PHE ALA ASP GLY LEU LEU GLN VAL LEU VAL CYS THR ALA          
SEQRES  65 B 2163  THR LEU ALA TRP GLY VAL ASN LEU PRO ALA HIS THR VAL          
SEQRES  66 B 2163  ILE ILE LYS GLY THR ASP VAL TYR SER PRO GLU LYS GLY          
SEQRES  67 B 2163  SER TRP GLU GLN LEU SER PRO GLN ASP VAL LEU GLN MET          
SEQRES  68 B 2163  LEU GLY ARG ALA GLY ARG PRO ARG TYR ASP THR PHE GLY          
SEQRES  69 B 2163  GLU GLY ILE ILE ILE THR ASP GLN SER ASN VAL GLN TYR          
SEQRES  70 B 2163  TYR LEU SER VAL LEU ASN GLN GLN LEU PRO ILE GLU SER          
SEQRES  71 B 2163  GLN PHE VAL SER LYS LEU VAL ASP ASN LEU ASN ALA GLU          
SEQRES  72 B 2163  VAL VAL ALA GLY ASN ILE LYS CYS ARG ASN ASP ALA VAL          
SEQRES  73 B 2163  ASN TRP LEU ALA TYR THR TYR LEU TYR VAL ARG MET LEU          
SEQRES  74 B 2163  ALA SER PRO MET LEU TYR LYS VAL PRO ASP ILE SER SER          
SEQRES  75 B 2163  ASP GLY GLN LEU LYS LYS PHE ARG GLU SER LEU VAL HIS          
SEQRES  76 B 2163  SER ALA LEU CYS ILE LEU LYS GLU GLN GLU LEU VAL LEU          
SEQRES  77 B 2163  TYR ASP ALA GLU ASN ASP VAL ILE GLU ALA THR ASP LEU          
SEQRES  78 B 2163  GLY ASN ILE ALA SER SER PHE TYR ILE ASN HIS ALA SER          
SEQRES  79 B 2163  MET ASP VAL TYR ASN ARG GLU LEU ASP GLU HIS THR THR          
SEQRES  80 B 2163  GLN ILE ASP LEU PHE ARG ILE PHE SER MET SER GLU GLU          
SEQRES  81 B 2163  PHE LYS TYR VAL SER VAL ARG TYR GLU GLU LYS ARG GLU          
SEQRES  82 B 2163  LEU LYS GLN LEU LEU GLU LYS ALA PRO ILE PRO ILE ARG          
SEQRES  83 B 2163  GLU ASP ILE ASP ASP PRO LEU ALA LYS VAL ASN VAL LEU          
SEQRES  84 B 2163  LEU GLN SER TYR PHE SER GLN LEU LYS PHE GLU GLY PHE          
SEQRES  85 B 2163  ALA LEU ASN SER ASP ILE VAL PHE ILE HIS GLN ASN ALA          
SEQRES  86 B 2163  GLY ARG LEU LEU ARG ALA MET PHE GLU ILE CYS LEU LYS          
SEQRES  87 B 2163  ARG GLY TRP GLY HIS PRO THR ARG MET LEU LEU ASN LEU          
SEQRES  88 B 2163  CYS LYS SER ALA THR THR LYS MET TRP PRO THR ASN CYS          
SEQRES  89 B 2163  PRO LEU ARG GLN PHE LYS THR CYS PRO VAL GLU VAL ILE          
SEQRES  90 B 2163  LYS ARG LEU GLU ALA SER THR VAL PRO TRP GLY ASP TYR          
SEQRES  91 B 2163  LEU GLN LEU GLU THR PRO ALA GLU VAL GLY ARG ALA ILE          
SEQRES  92 B 2163  ARG SER GLU LYS TYR GLY LYS GLN VAL TYR ASP LEU LEU          
SEQRES  93 B 2163  LYS ARG PHE PRO LYS MET SER VAL THR CYS ASN ALA GLN          
SEQRES  94 B 2163  PRO ILE THR ARG SER VAL MET ARG PHE ASN ILE GLU ILE          
SEQRES  95 B 2163  ILE ALA ASP TRP ILE TRP ASP MET ASN VAL HIS GLY SER          
SEQRES  96 B 2163  LEU GLU PRO PHE LEU LEU MET LEU GLU ASP THR ASP GLY          
SEQRES  97 B 2163  ASP SER ILE LEU TYR TYR ASP VAL LEU PHE ILE THR PRO          
SEQRES  98 B 2163  ASP ILE VAL GLY HIS GLU PHE THR LEU SER PHE THR TYR          
SEQRES  99 B 2163  GLU LEU LYS GLN HIS ASN GLN ASN ASN LEU PRO PRO ASN          
SEQRES 100 B 2163  PHE PHE LEU THR LEU ILE SER GLU ASN TRP TRP HIS SER          
SEQRES 101 B 2163  GLU PHE GLU ILE PRO VAL SER PHE ASN GLY PHE LYS LEU          
SEQRES 102 B 2163  PRO LYS LYS PHE PRO PRO PRO THR PRO LEU LEU GLU ASN          
SEQRES 103 B 2163  ILE SER ILE SER THR SER GLU LEU GLY ASN ASP ASP PHE          
SEQRES 104 B 2163  SER GLU VAL PHE GLU PHE LYS THR PHE ASN LYS ILE GLN          
SEQRES 105 B 2163  SER GLN VAL PHE GLU SER LEU TYR ASN SER ASN ASP SER          
SEQRES 106 B 2163  VAL PHE VAL GLY SER GLY LYS GLY THR GLY LYS THR ALA          
SEQRES 107 B 2163  MET ALA GLU LEU ALA LEU LEU ASN HIS TRP ARG GLN ASN          
SEQRES 108 B 2163  LYS GLY ARG ALA VAL TYR ILE ASN PRO SER GLY GLU LYS          
SEQRES 109 B 2163  ILE ASP PHE LEU LEU SER ASP TRP ASN LYS ARG PHE SER          
SEQRES 110 B 2163  HIS LEU ALA GLY GLY LYS ILE ILE ASN LYS LEU GLY ASN          
SEQRES 111 B 2163  ASP PRO SER LEU ASN LEU LYS LEU LEU ALA LYS SER HIS          
SEQRES 112 B 2163  VAL LEU LEU ALA THR PRO VAL GLN PHE GLU LEU LEU SER          
SEQRES 113 B 2163  ARG ARG TRP ARG GLN ARG LYS ASN ILE GLN SER LEU GLU          
SEQRES 114 B 2163  LEU MET ILE TYR ASP ASP ALA HIS GLU ILE SER GLN GLY          
SEQRES 115 B 2163  VAL TYR GLY ALA VAL TYR GLU THR LEU ILE SER ARG MET          
SEQRES 116 B 2163  ILE PHE ILE ALA THR GLN LEU GLU LYS LYS ILE ARG PHE          
SEQRES 117 B 2163  VAL CYS LEU SER ASN CYS LEU ALA ASN ALA ARG ASP PHE          
SEQRES 118 B 2163  GLY GLU TRP ALA GLY MET THR LYS SER ASN ILE TYR ASN          
SEQRES 119 B 2163  PHE SER PRO SER GLU ARG ILE GLU PRO LEU GLU ILE ASN          
SEQRES 120 B 2163  ILE GLN SER PHE LYS ASP VAL GLU HIS ILE SER PHE ASN          
SEQRES 121 B 2163  PHE SER MET LEU GLN MET ALA PHE GLU ALA SER ALA ALA          
SEQRES 122 B 2163  ALA ALA GLY ASN ARG ASN SER SER SER VAL PHE LEU PRO          
SEQRES 123 B 2163  SER ARG LYS ASP CYS MET GLU VAL ALA SER ALA PHE MET          
SEQRES 124 B 2163  LYS PHE SER LYS ALA ILE GLU TRP ASP MET LEU ASN VAL          
SEQRES 125 B 2163  GLU GLU GLU GLN ILE VAL PRO TYR ILE GLU LYS LEU THR          
SEQRES 126 B 2163  ASP GLY HIS LEU ARG ALA PRO LEU LYS HIS GLY VAL GLY          
SEQRES 127 B 2163  ILE LEU TYR LYS GLY MET ALA SER ASN ASP GLU ARG ILE          
SEQRES 128 B 2163  VAL LYS ARG LEU TYR GLU TYR GLY ALA VAL SER VAL LEU          
SEQRES 129 B 2163  LEU ILE SER LYS ASP CYS SER ALA PHE ALA CYS LYS THR          
SEQRES 130 B 2163  ASP GLU VAL ILE ILE LEU GLY THR ASN LEU TYR ASP GLY          
SEQRES 131 B 2163  ALA GLU HIS LYS TYR MET PRO TYR THR ILE ASN GLU LEU          
SEQRES 132 B 2163  LEU GLU MET VAL GLY LEU ALA SER GLY ASN ASP SER MET          
SEQRES 133 B 2163  ALA GLY LYS VAL LEU ILE LEU THR SER HIS ASN MET LYS          
SEQRES 134 B 2163  ALA TYR TYR LYS LYS PHE LEU ILE GLU PRO LEU PRO THR          
SEQRES 135 B 2163  GLU SER TYR LEU GLN TYR ILE ILE HIS ASP THR LEU ASN          
SEQRES 136 B 2163  ASN GLU ILE ALA ASN SER ILE ILE GLN SER LYS GLN ASP          
SEQRES 137 B 2163  CYS VAL ASP TRP PHE THR TYR SER TYR PHE TYR ARG ARG          
SEQRES 138 B 2163  ILE HIS VAL ASN PRO SER TYR TYR GLY VAL ARG ASP THR          
SEQRES 139 B 2163  SER PRO HIS GLY ILE SER VAL PHE LEU SER ASN LEU VAL          
SEQRES 140 B 2163  GLU THR CYS LEU ASN ASP LEU VAL GLU SER SER PHE ILE          
SEQRES 141 B 2163  GLU ILE ASP ASP THR GLU ALA GLU VAL THR ALA GLU VAL          
SEQRES 142 B 2163  ASN GLY GLY ASP ASP GLU ALA THR GLU ILE ILE SER THR          
SEQRES 143 B 2163  LEU SER ASN GLY LEU ILE ALA SER HIS TYR GLY VAL SER          
SEQRES 144 B 2163  PHE PHE THR ILE GLN SER PHE VAL SER SER LEU SER ASN          
SEQRES 145 B 2163  THR SER THR LEU LYS ASN MET LEU TYR VAL LEU SER THR          
SEQRES 146 B 2163  ALA VAL GLU PHE GLU SER VAL PRO LEU ARG LYS GLY ASP          
SEQRES 147 B 2163  ARG ALA LEU LEU VAL LYS LEU SER LYS ARG LEU PRO LEU          
SEQRES 148 B 2163  ARG PHE PRO GLU HIS THR SER SER GLY SER VAL SER PHE          
SEQRES 149 B 2163  LYS VAL PHE LEU LEU LEU GLN ALA TYR PHE SER ARG LEU          
SEQRES 150 B 2163  GLU LEU PRO VAL ASP PHE GLN ASN ASP LEU LYS ASP ILE          
SEQRES 151 B 2163  LEU GLU LYS VAL VAL PRO LEU ILE ASN VAL VAL VAL ASP          
SEQRES 152 B 2163  ILE LEU SER ALA ASN GLY TYR LEU ASN ALA THR THR ALA          
SEQRES 153 B 2163  MET ASP LEU ALA GLN MET LEU ILE GLN GLY VAL TRP ASP          
SEQRES 154 B 2163  VAL ASP ASN PRO LEU ARG GLN ILE PRO HIS PHE ASN ASN          
SEQRES 155 B 2163  LYS ILE LEU GLU LYS CYS LYS GLU ILE ASN VAL GLU THR          
SEQRES 156 B 2163  VAL TYR ASP ILE MET ALA LEU GLU ASP GLU GLU ARG ASP          
SEQRES 157 B 2163  GLU ILE LEU THR LEU THR ASP SER GLN LEU ALA GLN VAL          
SEQRES 158 B 2163  ALA ALA PHE VAL ASN ASN TYR PRO ASN VAL GLU LEU THR          
SEQRES 159 B 2163  TYR SER LEU ASN ASN SER ASP SER LEU ILE SER GLY VAL          
SEQRES 160 B 2163  LYS GLN LYS ILE THR ILE GLN LEU THR ARG ASP VAL GLU          
SEQRES 161 B 2163  PRO GLU ASN LEU GLN VAL THR SER GLU LYS TYR PRO PHE          
SEQRES 162 B 2163  ASP LYS LEU GLU SER TRP TRP LEU VAL LEU GLY GLU VAL          
SEQRES 163 B 2163  SER LYS LYS GLU LEU TYR ALA ILE LYS LYS VAL THR LEU          
SEQRES 164 B 2163  ASN LYS GLU THR GLN GLN TYR GLU LEU GLU PHE ASP THR          
SEQRES 165 B 2163  PRO THR SER GLY LYS HIS ASN LEU THR ILE TRP CYS VAL          
SEQRES 166 B 2163  CYS ASP SER TYR LEU ASP ALA ASP LYS GLU LEU SER PHE          
SEQRES 167 B 2163  GLU ILE ASN VAL LYS                                          
HELIX    1 AA1 UNK x   21  UNK x   46  1                                  26    
HELIX    2 AA2 UNK x   53  UNK x   62  1                                  10    
HELIX    3 AA3 UNK x  102  UNK x  120  1                                  19    
HELIX    4 AA4 ALA A  752  MET A  770  1                                  19    
HELIX    5 AA5 ILE A  774  ASN A  796  1                                  23    
HELIX    6 AA6 PRO A  805  GLY A  837  1                                  33    
HELIX    7 AA7 THR A  843  GLY A  871  1                                  29    
HELIX    8 AA8 THR A  875  SER A  894  1                                  20    
HELIX    9 AA9 ASP A  908  LYS A  926  1                                  19    
HELIX   10 AB1 ASN A  930  ASN A  946  1                                  17    
HELIX   11 AB2 ASN A  946  GLN A  961  1                                  16    
HELIX   12 AB3 ASP A  985  LYS A 1007  1                                  23    
HELIX   13 AB4 ILE A 1020  ASN A 1034  1                                  15    
HELIX   14 AB5 MET A 1057  ILE A 1061  5                                   5    
HELIX   15 AB6 ASP A 1062  VAL A 1074  1                                  13    
HELIX   16 AB7 ASP A 1075  ASN A 1087  1                                  13    
HELIX   17 AB8 PHE A 1109  GLY A 1127  1                                  19    
HELIX   18 AB9 GLY A 1127  GLY A 1136  1                                  10    
HELIX   19 AC1 SER A 1149  HIS A 1156  1                                   8    
HELIX   20 AC2 GLU A 1175  ASN A 1190  1                                  16    
HELIX   21 AC3 ILE A 1216  VAL A 1234  1                                  19    
HELIX   22 AC4 GLN A 1273  MET A 1275  5                                   3    
HELIX   23 AC5 SER A 1305  MET A 1321  1                                  17    
HELIX   24 AC6 THR A 1327  ARG A 1347  1                                  21    
HELIX   25 AC7 GLU A 1348  VAL A 1351  5                                   4    
HELIX   26 AC8 THR A 1353  ASN A 1376  1                                  24    
HELIX   27 AC9 PRO A 1385  THR A 1390  1                                   6    
HELIX   28 AD1 PRO A 1408  SER A 1413  5                                   6    
HELIX   29 AD2 THR A 1439  ILE A 1444  5                                   6    
HELIX   30 AD3 THR A 1446  GLN A 1471  1                                  26    
HELIX   31 AD4 ARG A 1490  PHE A 1495  1                                   6    
HELIX   32 AD5 ASP A 1498  ALA A 1503  1                                   6    
HELIX   33 AD6 GLY A 1507  LYS A 1515  1                                   9    
HELIX   34 AD7 GLN A 1516  SER A 1518  5                                   3    
HELIX   35 AD8 ASN A 1529  GLY A 1534  1                                   6    
HELIX   36 AD9 LEU A 1539  LEU A 1550  1                                  12    
HELIX   37 AE1 GLY A 1551  THR A 1560  1                                  10    
HELIX   38 AE2 PHE A 1562  GLY A 1566  5                                   5    
HELIX   39 AE3 LYS A 1577  GLN A 1586  1                                  10    
HELIX   40 AE4 THR A 1591  ASN A 1615  1                                  25    
HELIX   41 AE5 ILE A 1638  PHE A 1649  1                                  12    
HELIX   42 AE6 HIS A 1652  GLU A 1672  1                                  21    
HELIX   43 AE7 GLU A 1672  GLN A 1677  1                                   6    
HELIX   44 AE8 HIS A 1687  LYS A 1693  5                                   7    
HELIX   45 AE9 ASP A 1747  ASP A 1762  1                                  16    
HELIX   46 AF1 GLY A 1793  ASN A 1809  1                                  17    
HELIX   47 AF2 ASN A 1809  GLN A 1824  1                                  16    
HELIX   48 AF3 TYR A 1840  ASN A 1845  5                                   6    
HELIX   49 AF4 HIS A 1895  ALA A 1900  5                                   6    
HELIX   50 AF5 ARG A 1904  LEU A 1924  1                                  21    
HELIX   51 AF6 ARG A 1937  ALA A 1939  5                                   3    
HELIX   52 AF7 MET A 1940  MET A 1948  1                                   9    
HELIX   53 AF8 LEU A 1963  MET A 1969  5                                   7    
HELIX   54 AF9 ILE A 1971  ALA A 1981  1                                  11    
HELIX   55 AG1 ASP A 1994  ARG A 1998  5                                   5    
HELIX   56 AG2 SER A 2000  ASN A 2018  1                                  19    
HELIX   57 AG3 ASN A 2018  LEU A 2027  1                                  10    
HELIX   58 AG4 THR A 2044  ASN A 2068  1                                  25    
HELIX   59 AG5 LEU A 2074  LEU A 2084  1                                  11    
HELIX   60 AG6 SER A 2092  ALA A 2104  1                                  13    
HELIX   61 AG7 THR H  114  LYS H  145  1                                  32    
HELIX   62 AG8 ASN H  147  ASN H  164  1                                  18    
HELIX   63 AG9 LEU J  159  LEU J  170  1                                  12    
HELIX   64 AH1 GLN J  171  ASN J  177  1                                   7    
HELIX   65 AH2 SER J  186  THR J  198  1                                  13    
HELIX   66 AH3 ASP J  206  ASP J  210  5                                   5    
HELIX   67 AH4 THR J  219  ALA J  236  1                                  18    
HELIX   68 AH5 PRO J  241  ARG J  255  1                                  15    
HELIX   69 AH6 SER J  258  CYS J  271  1                                  14    
HELIX   70 AH7 SER J  274  HIS J  285  1                                  12    
HELIX   71 AH8 VAL J  289  ASN J  303  1                                  15    
HELIX   72 AH9 SER J  306  GLU J  317  1                                  12    
HELIX   73 AI1 THR J  319  ILE J  334  1                                  16    
HELIX   74 AI2 ASP J  337  GLU J  348  1                                  12    
HELIX   75 AI3 LYS J  351  ILE J  365  1                                  15    
HELIX   76 AI4 SER J  368  SER J  380  1                                  13    
HELIX   77 AI5 TYR J  381  LEU J  395  1                                  15    
HELIX   78 AI6 ILE J  401  GLU J  410  1                                  10    
HELIX   79 AI7 VAL J  422  ASN J  435  1                                  14    
HELIX   80 AI8 SER J  442  ALA J  454  1                                  13    
HELIX   81 AI9 SER J  457  GLY J  476  1                                  20    
HELIX   82 AJ1 GLU J  479  LYS J  491  1                                  13    
HELIX   83 AJ2 SER J  495  ASP J  509  1                                  15    
HELIX   84 AJ3 CYS J  511  TYR J  526  1                                  16    
HELIX   85 AJ4 GLU J  531  THR J  543  1                                  13    
HELIX   86 AJ5 ASP J  548  SER J  557  1                                  10    
HELIX   87 AJ6 GLY J  559  GLN J  572  1                                  14    
HELIX   88 AJ7 THR J  576  PHE J  589  1                                  14    
HELIX   89 AJ8 LEU J  594  LEU J  608  1                                  15    
HELIX   90 AJ9 GLN J  609  LEU J  624  1                                  16    
HELIX   91 AK1 GLU J  625  PHE J  627  5                                   3    
HELIX   92 AK2 GLU J  633  ASN J  649  1                                  17    
HELIX   93 AK3 ALA J  652  PHE J  664  1                                  13    
HELIX   94 AK4 CYS J  667  MET J  681  1                                  15    
HELIX   95 AK5 ASN J  683  VAL J  698  1                                  16    
HELIX   96 AK6 CYS J  701  ASP J  715  1                                  15    
HELIX   97 AK7 ASN J  718  ASN J  733  1                                  16    
HELIX   98 AK8 VAL J  737  LEU J  750  1                                  14    
HELIX   99 AK9 LEU J  753  PHE J  767  1                                  15    
HELIX  100 AL1 ASN J  770  GLY J  784  1                                  15    
HELIX  101 AL2 LEU J  789  GLN J  802  1                                  14    
HELIX  102 AL3 ASP J  804  ALA J  819  1                                  16    
HELIX  103 AL4 GLN J  820  CYS J  835  1                                  16    
HELIX  104 AL5 GLY J  839  LEU J  852  1                                  14    
HELIX  105 AL6 THR J  856  PHE J  863  1                                   8    
HELIX  106 AL7 GLY J  871  ASN J  880  1                                  10    
HELIX  107 AL8 ARG J  889  ASP J  898  1                                  10    
HELIX  108 AL9 THR D   11  GLU D   22  1                                  12    
HELIX  109 AM1 ASP D   36  VAL D   53  1                                  18    
HELIX  110 AM2 ASP D  109  ASN D  127  1                                  19    
HELIX  111 AM3 PRO F   43  GLU F   45  5                                   3    
HELIX  112 AM4 ILE F   46  ALA F   58  1                                  13    
HELIX  113 AM5 ARG F   64  VAL F   78  1                                  15    
HELIX  114 AM6 ASP F   79  GLN F   87  1                                   9    
HELIX  115 AM7 PRO F   96  SER F  121  1                                  26    
HELIX  116 AM8 PRO F  125  ILE F  131  1                                   7    
HELIX  117 AM9 SER F  133  ASN F  146  1                                  14    
HELIX  118 AN1 ASP F  155  LYS F  164  1                                  10    
HELIX  119 AN2 THR F  168  SER F  182  1                                  15    
HELIX  120 AN3 ASP F  190  ALA F  226  1                                  37    
HELIX  121 AN4 ALA F  226  VAL F  233  1                                   8    
HELIX  122 AN5 GLY F  234  GLY F  246  1                                  13    
HELIX  123 AN6 GLY F  247  ILE F  254  1                                   8    
HELIX  124 AN7 PRO F  255  ALA F  260  1                                   6    
HELIX  125 AN8 GLU F  282  ALA F  287  1                                   6    
HELIX  126 AN9 SER F  288  LYS F  293  1                                   6    
HELIX  127 AO1 VAL F  298  GLN F  320  1                                  23    
HELIX  128 AO2 VAL F  328  GLU F  346  1                                  19    
HELIX  129 AO3 GLY F  369  ARG F  380  1                                  12    
HELIX  130 AO4 SER F  382  ASN F  389  1                                   8    
HELIX  131 AO5 LEU F  410  ASN F  414  5                                   5    
HELIX  132 AO6 THR F  415  GLY F  422  1                                   8    
HELIX  133 AO7 THR F  438  ILE F  457  1                                  20    
HELIX  134 AO8 LEU G  151  HIS G  164  1                                  14    
HELIX  135 AO9 LYS G  177  THR G  189  1                                  13    
HELIX  136 AP1 LYS G  195  ILE G  200  5                                   6    
HELIX  137 AP2 THR G  237  LEU G  262  1                                  26    
HELIX  138 AP3 ASP G  289  ASN G  330  1                                  42    
HELIX  139 AP4 ASN G  349  LEU G  363  1                                  15    
HELIX  140 AP5 ASN G  385  LYS G  398  1                                  14    
HELIX  141 AP6 ASP G  447  GLY G  456  1                                  10    
HELIX  142 AP7 GLN G  457  ASP G  459  5                                   3    
HELIX  143 AP8 ASP K   13  LEU K   30  1                                  18    
HELIX  144 AP9 GLY K   36  GLY K   47  1                                  12    
HELIX  145 AQ1 PRO K   60  LEU K   64  5                                   5    
HELIX  146 AQ2 LEU K   65  ASN K   75  1                                  11    
HELIX  147 AQ3 SER K   83  GLY K   92  1                                  10    
HELIX  148 AQ4 ILE K  110  ILE K  126  1                                  17    
HELIX  149 AQ5 LYS B  364  ILE B  370  1                                   7    
HELIX  150 AQ6 LEU B  373  TYR B  389  1                                  17    
HELIX  151 AQ7 ARG B  399  GLN B  407  1                                   9    
HELIX  152 AQ8 GLU B  412  ILE B  423  1                                  12    
HELIX  153 AQ9 PRO B  425  LYS B  433  1                                   9    
SHEET    1 AA1 4 VAL A 981  SER A 983  0                                        
SHEET    2 AA1 4 VAL A 967  THR A 970 -1  N  ASP A 968   O  SER A 983           
SHEET    3 AA1 4 VAL A1089  ASN A1091  1  O  ASN A1091   N  VAL A 967           
SHEET    4 AA1 4 HIS A1097  VAL A1098 -1  O  HIS A1097   N  ILE A1090           
SHEET    1 AA2 5 ILE A1013  LYS A1014  0                                        
SHEET    2 AA2 5 ILE A1158  TYR A1164  1  O  ARG A1163   N  LYS A1014           
SHEET    3 AA2 5 ARG A1167  PHE A1174 -1  O  LEU A1171   N  LEU A1160           
SHEET    4 AA2 5 SER A1046  THR A1053 -1  N  VAL A1048   O  PHE A1172           
SHEET    5 AA2 5 ALA A1246  TYR A1251 -1  O  TYR A1251   N  ALA A1047           
SHEET    1 AA3 4 LEU A1258  MET A1262  0                                        
SHEET    2 AA3 4 PHE A1265  PRO A1271 -1  O  ILE A1269   N  LEU A1258           
SHEET    3 AA3 4 ARG A1296  VAL A1304 -1  O  LYS A1299   N  LEU A1270           
SHEET    4 AA3 4 VAL A1285  VAL A1289 -1  N  LEU A1288   O  ALA A1298           
SHEET    1 AA4 2 TRP A1414  GLN A1417  0                                        
SHEET    2 AA4 2 ILE A1422  PHE A1425 -1  O  PHE A1425   N  TRP A1414           
SHEET    1 AA5 3 ILE A1825  GLN A1827  0                                        
SHEET    2 AA5 3 LEU A1573  GLU A1576 -1  N  PHE A1574   O  TYR A1826           
SHEET    3 AA5 3 ARG F 390  GLU F 392 -1  O  MET F 391   N  TRP A1575           
SHEET    1 AA6 6 ILE A1678  LYS A1683  0                                        
SHEET    2 AA6 6 ILE A1701  VAL A1711 -1  O  GLU A1704   N  GLU A1679           
SHEET    3 AA6 6 LEU A1727  ARG A1739 -1  O  THR A1729   N  TRP A1709           
SHEET    4 AA6 6 VAL A1773  ASP A1778  1  O  ILE A1777   N  GLN A1737           
SHEET    5 AA6 6 MET A1783  GLY A1788 -1  O  ASP A1785   N  GLY A1776           
SHEET    6 AA6 6 SER A1715  LEU A1716 -1  N  SER A1715   O  GLY A1788           
SHEET    1 AA7 6 ALA A1955  ARG A1957  0                                        
SHEET    2 AA7 6 GLN A1932  VAL A1935  1  N  VAL A1935   O  ARG A1957           
SHEET    3 AA7 6 LYS A1849  ASP A1853  1  N  LEU A1850   O  ILE A1934           
SHEET    4 AA7 6 GLY A1877  LEU A1882 -1  O  LEU A1882   N  PHE A1851           
SHEET    5 AA7 6 HIS A1888  ILE A1894 -1  O  ILE A1894   N  GLY A1877           
SHEET    6 AA7 6 GLN A1985  ASN A1990 -1  O  GLN A1985   N  ILE A1893           
SHEET    1 AA8 4 GLU H 166  LEU H 172  0                                        
SHEET    2 AA8 4 SER H 460  ASN H 465 -1  O  ILE H 461   N  GLN H 171           
SHEET    3 AA8 4 LEU H 452  GLY H 456 -1  N  SER H 454   O  LYS H 462           
SHEET    4 AA8 4 ILE H 440  ILE H 445 -1  N  SER H 442   O  GLY H 455           
SHEET    1 AA9 4 ALA H 180  LEU H 183  0                                        
SHEET    2 AA9 4 VAL H 189  GLY H 193 -1  O  ALA H 191   N  SER H 182           
SHEET    3 AA9 4 LEU H 199  ASN H 203 -1  O  LEU H 202   N  VAL H 190           
SHEET    4 AA9 4 GLN H 208  THR H 211 -1  O  LEU H 210   N  VAL H 201           
SHEET    1 AB1 4 ILE H 221  ASP H 225  0                                        
SHEET    2 AB1 4 GLN H 233  ALA H 238 -1  O  ILE H 235   N  ASP H 225           
SHEET    3 AB1 4 ILE H 243  TYR H 248 -1  O  LYS H 244   N  SER H 236           
SHEET    4 AB1 4 LEU H 255  LEU H 261 -1  O  LEU H 258   N  ASN H 245           
SHEET    1 AB2 3 ILE H 268  TYR H 273  0                                        
SHEET    2 AB2 3 PHE H 279  SER H 284 -1  O  ALA H 283   N  ASP H 270           
SHEET    3 AB2 3 TRP H 289  ASP H 293 -1  O  ARG H 290   N  SER H 282           
SHEET    1 AB3 4 VAL H 310  PHE H 315  0                                        
SHEET    2 AB3 4 LEU H 321  GLY H 326 -1  O  CYS H 323   N  SER H 314           
SHEET    3 AB3 4 SER H 331  ASP H 335 -1  O  TRP H 334   N  VAL H 322           
SHEET    4 AB3 4 SER H 340  LYS H 341 -1  O  SER H 340   N  ASP H 335           
SHEET    1 AB4 4 THR H 354  TRP H 357  0                                        
SHEET    2 AB4 4 VAL H 364  GLY H 367 -1  O  ALA H 365   N  ALA H 356           
SHEET    3 AB4 4 ILE H 372  TRP H 376 -1  O  TRP H 376   N  VAL H 364           
SHEET    4 AB4 4 ASN H 387  LEU H 390 -1  O  ILE H 389   N  ILE H 373           
SHEET    1 AB5 4 VAL H 396  ARG H 400  0                                        
SHEET    2 AB5 4 LYS H 409  GLY H 414 -1  O  VAL H 411   N  ARG H 400           
SHEET    3 AB5 4 LEU H 418  SER H 423 -1  O  TYR H 422   N  LEU H 410           
SHEET    4 AB5 4 LYS H 429  ALA H 434 -1  O  MET H 430   N  VAL H 421           
SHEET    1 AB6 5 GLN D   8  LEU D   9  0                                        
SHEET    2 AB6 5 ALA D  57  CYS D  62  1  O  LEU D  61   N  LEU D   9           
SHEET    3 AB6 5 LEU D  26  PHE D  31  1  N  VAL D  28   O  VAL D  58           
SHEET    4 AB6 5 THR D  81  TYR D  86 -1  O  MET D  83   N  ILE D  29           
SHEET    5 AB6 5 LYS D  89  HIS D  90 -1  O  LYS D  89   N  TYR D  86           
SHEET    1 AB7 4 LYS G 366  ARG G 371  0                                        
SHEET    2 AB7 4 GLY G 378  GLY G 384 -1  O  VAL G 383   N  LYS G 366           
SHEET    3 AB7 4 TYR G 337  PHE G 344 -1  N  PHE G 342   O  ILE G 380           
SHEET    4 AB7 4 ILE G 424  LYS G 426 -1  O  SER G 425   N  GLN G 343           
SHEET    1 AB8 4 LYS G 366  ARG G 371  0                                        
SHEET    2 AB8 4 GLY G 378  GLY G 384 -1  O  VAL G 383   N  LYS G 366           
SHEET    3 AB8 4 TYR G 337  PHE G 344 -1  N  PHE G 342   O  ILE G 380           
SHEET    4 AB8 4 TYR G 431  LEU G 432 -1  O  LEU G 432   N  TYR G 337           
SHEET    1 AB9 2 PHE G 406  LEU G 408  0                                        
SHEET    2 AB9 2 ILE G 415  MET G 417 -1  O  MET G 417   N  PHE G 406           
SHEET    1 AC1 4 LEU K  33  LYS K  35  0                                        
SHEET    2 AC1 4 ALA K 100  THR K 103 -1  O  SER K 101   N  LYS K  34           
SHEET    3 AC1 4 SER K  49  ALA K  55 -1  N  GLU K  50   O  ILE K 102           
SHEET    4 AC1 4 TYR K  78  VAL K  81  1  O  VAL K  81   N  MET K  54           
CISPEP   1 LYS A 1014    PRO A 1015          0         2.75                     
CISPEP   2 ILE A 1488    PRO A 1489          0        -5.23                     
CISPEP   3 GLU H  404    ASP H  405          0         8.53                     
CISPEP   4 THR J  239    ASN J  240          0        13.13                     
CISPEP   5 ALA J  254    ARG J  255          0        14.57                     
CISPEP   6 SER F   61    PRO F   62          0         8.27                     
CISPEP   7 LEU F   95    PRO F   96          0        14.07                     
CISPEP   8 PHE K    9    PRO K   10          0         5.14                     
CISPEP   9 GLU K   59    PRO K   60          0         9.38                     
CRYST1  543.400  543.400  543.400  90.00  90.00  90.00 P 1           1          
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      0.001840  0.000000  0.000000        0.00000                         
SCALE2      0.000000  0.001840  0.000000        0.00000                         
SCALE3      0.000000  0.000000  0.001840        0.00000                         
(ATOM LINES ARE NOT SHOWN.)
END                                                                             
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