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Database: PDB
Entry: 5LN3
LinkDB: 5LN3
Original site: 5LN3 
HEADER    HYDROLASE                               03-AUG-16   5LN3              
TITLE     THE HUMAN 26S PROTEASOME AT 6.8 ANG.                                  
CAVEAT     5LN3    PRO H 311 HAS WRONG CHIRALITY AT ATOM CA THR N 752 HAS WRONG 
CAVEAT   2 5LN3    CHIRALITY AT ATOM CA                                         
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 2;            
COMPND   3 CHAIN: Z;                                                            
COMPND   4 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN1,26S PROTEASOME       
COMPND   5 REGULATORY SUBUNIT S2,26S PROTEASOME SUBUNIT P97,PROTEIN 55.11,TUMOR 
COMPND   6 NECROSIS FACTOR TYPE 1 RECEPTOR-ASSOCIATED PROTEIN 2;                
COMPND   7 MOL_ID: 2;                                                           
COMPND   8 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-6;                            
COMPND   9 CHAIN: 1;                                                            
COMPND  10 SYNONYM: MACROPAIN DELTA CHAIN,MULTICATALYTIC ENDOPEPTIDASE COMPLEX  
COMPND  11 DELTA CHAIN,PROTEASOME DELTA CHAIN,PROTEASOME SUBUNIT Y;             
COMPND  12 EC: 3.4.25.1;                                                        
COMPND  13 MOL_ID: 3;                                                           
COMPND  14 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-7;                            
COMPND  15 CHAIN: 2;                                                            
COMPND  16 SYNONYM: MACROPAIN CHAIN Z,MULTICATALYTIC ENDOPEPTIDASE COMPLEX CHAIN
COMPND  17 Z,PROTEASOME SUBUNIT Z;                                              
COMPND  18 EC: 3.4.25.1;                                                        
COMPND  19 MOL_ID: 4;                                                           
COMPND  20 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-3;                            
COMPND  21 CHAIN: 3;                                                            
COMPND  22 SYNONYM: PROTEASOME CHAIN 13,PROTEASOME COMPONENT C10-II,PROTEASOME  
COMPND  23 THETA CHAIN;                                                         
COMPND  24 EC: 3.4.25.1;                                                        
COMPND  25 MOL_ID: 5;                                                           
COMPND  26 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-2;                            
COMPND  27 CHAIN: 4;                                                            
COMPND  28 SYNONYM: MACROPAIN SUBUNIT C7-I,MULTICATALYTIC ENDOPEPTIDASE COMPLEX 
COMPND  29 SUBUNIT C7-I,PROTEASOME COMPONENT C7-I;                              
COMPND  30 EC: 3.4.25.1;                                                        
COMPND  31 MOL_ID: 6;                                                           
COMPND  32 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-5;                            
COMPND  33 CHAIN: 5;                                                            
COMPND  34 SYNONYM: MACROPAIN EPSILON CHAIN,MULTICATALYTIC ENDOPEPTIDASE COMPLEX
COMPND  35 EPSILON CHAIN,PROTEASOME CHAIN 6,PROTEASOME EPSILON CHAIN,PROTEASOME 
COMPND  36 SUBUNIT MB1,PROTEASOME SUBUNIT X;                                    
COMPND  37 EC: 3.4.25.1;                                                        
COMPND  38 MOL_ID: 7;                                                           
COMPND  39 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-1;                            
COMPND  40 CHAIN: 6;                                                            
COMPND  41 SYNONYM: MACROPAIN SUBUNIT C5,MULTICATALYTIC ENDOPEPTIDASE COMPLEX   
COMPND  42 SUBUNIT C5,PROTEASOME COMPONENT C5,PROTEASOME GAMMA CHAIN;           
COMPND  43 EC: 3.4.25.1;                                                        
COMPND  44 MOL_ID: 8;                                                           
COMPND  45 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-4;                            
COMPND  46 CHAIN: 7;                                                            
COMPND  47 SYNONYM: 26 KDA PROSOMAL PROTEIN,PROS-26,MACROPAIN BETA CHAIN,       
COMPND  48 MULTICATALYTIC ENDOPEPTIDASE COMPLEX BETA CHAIN,PROTEASOME BETA      
COMPND  49 CHAIN,PROTEASOME CHAIN 3,HSN3;                                       
COMPND  50 EC: 3.4.25.1;                                                        
COMPND  51 MOL_ID: 9;                                                           
COMPND  52 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-6;                           
COMPND  53 CHAIN: A;                                                            
COMPND  54 SYNONYM: 27 KDA PROSOMAL PROTEIN,P27K,MACROPAIN IOTA CHAIN,          
COMPND  55 MULTICATALYTIC ENDOPEPTIDASE COMPLEX IOTA CHAIN,PROTEASOME IOTA      
COMPND  56 CHAIN;                                                               
COMPND  57 EC: 3.4.25.1;                                                        
COMPND  58 MOL_ID: 10;                                                          
COMPND  59 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-2;                           
COMPND  60 CHAIN: B;                                                            
COMPND  61 SYNONYM: MACROPAIN SUBUNIT C3,MULTICATALYTIC ENDOPEPTIDASE COMPLEX   
COMPND  62 SUBUNIT C3,PROTEASOME COMPONENT C3;                                  
COMPND  63 EC: 3.4.25.1;                                                        
COMPND  64 MOL_ID: 11;                                                          
COMPND  65 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-4;                           
COMPND  66 CHAIN: C;                                                            
COMPND  67 SYNONYM: MACROPAIN SUBUNIT C9,MULTICATALYTIC ENDOPEPTIDASE COMPLEX   
COMPND  68 SUBUNIT C9,PROTEASOME COMPONENT C9,PROTEASOME SUBUNIT L;             
COMPND  69 EC: 3.4.25.1;                                                        
COMPND  70 MOL_ID: 12;                                                          
COMPND  71 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-7;                           
COMPND  72 CHAIN: D;                                                            
COMPND  73 SYNONYM: PROTEASOME SUBUNIT RC6-1,PROTEASOME SUBUNIT XAPC7;          
COMPND  74 EC: 3.4.25.1;                                                        
COMPND  75 MOL_ID: 13;                                                          
COMPND  76 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-5;                           
COMPND  77 CHAIN: E;                                                            
COMPND  78 SYNONYM: MACROPAIN ZETA CHAIN,MULTICATALYTIC ENDOPEPTIDASE COMPLEX   
COMPND  79 ZETA CHAIN,PROTEASOME ZETA CHAIN;                                    
COMPND  80 EC: 3.4.25.1;                                                        
COMPND  81 MOL_ID: 14;                                                          
COMPND  82 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-1;                           
COMPND  83 CHAIN: F;                                                            
COMPND  84 SYNONYM: 30 KDA PROSOMAL PROTEIN,PROS-30,MACROPAIN SUBUNIT C2,       
COMPND  85 MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT C2,PROTEASOME COMPONENT 
COMPND  86 C2,PROTEASOME NU CHAIN;                                              
COMPND  87 EC: 3.4.25.1;                                                        
COMPND  88 MOL_ID: 15;                                                          
COMPND  89 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-3;                           
COMPND  90 CHAIN: G;                                                            
COMPND  91 SYNONYM: MACROPAIN SUBUNIT C8,MULTICATALYTIC ENDOPEPTIDASE COMPLEX   
COMPND  92 SUBUNIT C8,PROTEASOME COMPONENT C8;                                  
COMPND  93 EC: 3.4.25.1;                                                        
COMPND  94 MOL_ID: 16;                                                          
COMPND  95 MOLECULE: 26S PROTEASE REGULATORY SUBUNIT 7;                         
COMPND  96 CHAIN: H;                                                            
COMPND  97 SYNONYM: 26S PROTEASOME AAA-ATPASE SUBUNIT RPT1,PROTEASOME 26S       
COMPND  98 SUBUNIT ATPASE 2,PROTEIN MSS1;                                       
COMPND  99 MOL_ID: 17;                                                          
COMPND 100 MOLECULE: 26S PROTEASE REGULATORY SUBUNIT 4;                         
COMPND 101 CHAIN: I;                                                            
COMPND 102 SYNONYM: P26S4,26S PROTEASOME AAA-ATPASE SUBUNIT RPT2,PROTEASOME 26S 
COMPND 103 SUBUNIT ATPASE 1;                                                    
COMPND 104 MOL_ID: 18;                                                          
COMPND 105 MOLECULE: 26S PROTEASE REGULATORY SUBUNIT 8;                         
COMPND 106 CHAIN: J;                                                            
COMPND 107 SYNONYM: 26S PROTEASOME AAA-ATPASE SUBUNIT RPT6,PROTEASOME 26S       
COMPND 108 SUBUNIT ATPASE 5,PROTEASOME SUBUNIT P45,THYROID HORMONE RECEPTOR-    
COMPND 109 INTERACTING PROTEIN 1,TRIP1,P45/SUG;                                 
COMPND 110 MOL_ID: 19;                                                          
COMPND 111 MOLECULE: 26S PROTEASE REGULATORY SUBUNIT 6B;                        
COMPND 112 CHAIN: K;                                                            
COMPND 113 SYNONYM: 26S PROTEASOME AAA-ATPASE SUBUNIT RPT3,MB67-INTERACTING     
COMPND 114 PROTEIN,MIP224,PROTEASOME 26S SUBUNIT ATPASE 4,TAT-BINDING PROTEIN 7,
COMPND 115 TBP-7;                                                               
COMPND 116 MOL_ID: 20;                                                          
COMPND 117 MOLECULE: 26S PROTEASE REGULATORY SUBUNIT 10B;                       
COMPND 118 CHAIN: L;                                                            
COMPND 119 SYNONYM: 26S PROTEASOME AAA-ATPASE SUBUNIT RPT4,PROTEASOME 26S       
COMPND 120 SUBUNIT ATPASE 6,PROTEASOME SUBUNIT P42;                             
COMPND 121 MOL_ID: 21;                                                          
COMPND 122 MOLECULE: 26S PROTEASE REGULATORY SUBUNIT 6A;                        
COMPND 123 CHAIN: M;                                                            
COMPND 124 SYNONYM: 26S PROTEASOME AAA-ATPASE SUBUNIT RPT5,PROTEASOME 26S       
COMPND 125 SUBUNIT ATPASE 3,PROTEASOME SUBUNIT P50,TAT-BINDING PROTEIN 1,TBP-1; 
COMPND 126 MOL_ID: 22;                                                          
COMPND 127 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 1;            
COMPND 128 CHAIN: N;                                                            
COMPND 129 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN2,26S PROTEASOME       
COMPND 130 REGULATORY SUBUNIT S1,26S PROTEASOME SUBUNIT P112;                   
COMPND 131 MOL_ID: 23;                                                          
COMPND 132 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13;           
COMPND 133 CHAIN: O;                                                            
COMPND 134 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN9,26S PROTEASOME       
COMPND 135 REGULATORY SUBUNIT S11,26S PROTEASOME REGULATORY SUBUNIT P40.5;      
COMPND 136 MOL_ID: 24;                                                          
COMPND 137 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12;           
COMPND 138 CHAIN: P;                                                            
COMPND 139 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN5,26S PROTEASOME       
COMPND 140 REGULATORY SUBUNIT P55;                                              
COMPND 141 MOL_ID: 25;                                                          
COMPND 142 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11;           
COMPND 143 CHAIN: Q;                                                            
COMPND 144 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN6,26S PROTEASOME       
COMPND 145 REGULATORY SUBUNIT S9,26S PROTEASOME REGULATORY SUBUNIT P44.5;       
COMPND 146 MOL_ID: 26;                                                          
COMPND 147 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 6;            
COMPND 148 CHAIN: R;                                                            
COMPND 149 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN7,26S PROTEASOME       
COMPND 150 REGULATORY SUBUNIT S10,BREAST CANCER-ASSOCIATED PROTEIN SGA-113M,    
COMPND 151 PHOSPHONOFORMATE IMMUNO-ASSOCIATED PROTEIN 4,PROTEASOME REGULATORY   
COMPND 152 PARTICLE SUBUNIT P44S10,P42A;                                        
COMPND 153 MOL_ID: 27;                                                          
COMPND 154 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3;            
COMPND 155 CHAIN: S;                                                            
COMPND 156 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN3,26S PROTEASOME       
COMPND 157 REGULATORY SUBUNIT S3,PROTEASOME SUBUNIT P58;                        
COMPND 158 MOL_ID: 28;                                                          
COMPND 159 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8;            
COMPND 160 CHAIN: T;                                                            
COMPND 161 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN12,26S PROTEASOME      
COMPND 162 REGULATORY SUBUNIT S14,P31;                                          
COMPND 163 MOL_ID: 29;                                                          
COMPND 164 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 7;            
COMPND 165 CHAIN: U;                                                            
COMPND 166 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN8,26S PROTEASOME       
COMPND 167 REGULATORY SUBUNIT S12,MOV34 PROTEIN HOMOLOG,PROTEASOME SUBUNIT P40; 
COMPND 168 MOL_ID: 30;                                                          
COMPND 169 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 14;           
COMPND 170 CHAIN: V;                                                            
COMPND 171 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN11,26S PROTEASOME-     
COMPND 172 ASSOCIATED PAD1 HOMOLOG 1;                                           
COMPND 173 EC: 3.4.19.-;                                                        
COMPND 174 MOL_ID: 31;                                                          
COMPND 175 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4;            
COMPND 176 CHAIN: W;                                                            
COMPND 177 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN10,26S PROTEASOME      
COMPND 178 REGULATORY SUBUNIT S5A,ANTISECRETORY FACTOR 1,ASF,MULTIUBIQUITIN     
COMPND 179 CHAIN-BINDING PROTEIN;                                               
COMPND 180 MOL_ID: 32;                                                          
COMPND 181 MOLECULE: 26S PROTEASOME COMPLEX SUBUNIT DSS1;                       
COMPND 182 CHAIN: Y;                                                            
COMPND 183 SYNONYM: DELETED IN SPLIT HAND/SPLIT FOOT PROTEIN 1,SPLIT HAND/FOOT  
COMPND 184 DELETED PROTEIN 1,SPLIT HAND/FOOT MALFORMATION TYPE 1 PROTEIN        
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE   3 ORGANISM_COMMON: HUMAN;                                              
SOURCE   4 ORGANISM_TAXID: 9606;                                                
SOURCE   5 MOL_ID: 2;                                                           
SOURCE   6 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE   7 ORGANISM_COMMON: HUMAN;                                              
SOURCE   8 ORGANISM_TAXID: 9606;                                                
SOURCE   9 MOL_ID: 3;                                                           
SOURCE  10 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  11 ORGANISM_COMMON: HUMAN;                                              
SOURCE  12 ORGANISM_TAXID: 9606;                                                
SOURCE  13 MOL_ID: 4;                                                           
SOURCE  14 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  15 ORGANISM_COMMON: HUMAN;                                              
SOURCE  16 ORGANISM_TAXID: 9606;                                                
SOURCE  17 MOL_ID: 5;                                                           
SOURCE  18 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  19 ORGANISM_COMMON: HUMAN;                                              
SOURCE  20 ORGANISM_TAXID: 9606;                                                
SOURCE  21 MOL_ID: 6;                                                           
SOURCE  22 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  23 ORGANISM_COMMON: HUMAN;                                              
SOURCE  24 ORGANISM_TAXID: 9606;                                                
SOURCE  25 MOL_ID: 7;                                                           
SOURCE  26 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  27 ORGANISM_COMMON: HUMAN;                                              
SOURCE  28 ORGANISM_TAXID: 9606;                                                
SOURCE  29 MOL_ID: 8;                                                           
SOURCE  30 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  31 ORGANISM_COMMON: HUMAN;                                              
SOURCE  32 ORGANISM_TAXID: 9606;                                                
SOURCE  33 MOL_ID: 9;                                                           
SOURCE  34 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  35 ORGANISM_COMMON: HUMAN;                                              
SOURCE  36 ORGANISM_TAXID: 9606;                                                
SOURCE  37 MOL_ID: 10;                                                          
SOURCE  38 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  39 ORGANISM_COMMON: HUMAN;                                              
SOURCE  40 ORGANISM_TAXID: 9606;                                                
SOURCE  41 MOL_ID: 11;                                                          
SOURCE  42 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  43 ORGANISM_COMMON: HUMAN;                                              
SOURCE  44 ORGANISM_TAXID: 9606;                                                
SOURCE  45 MOL_ID: 12;                                                          
SOURCE  46 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  47 ORGANISM_COMMON: HUMAN;                                              
SOURCE  48 ORGANISM_TAXID: 9606;                                                
SOURCE  49 MOL_ID: 13;                                                          
SOURCE  50 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  51 ORGANISM_COMMON: HUMAN;                                              
SOURCE  52 ORGANISM_TAXID: 9606;                                                
SOURCE  53 MOL_ID: 14;                                                          
SOURCE  54 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  55 ORGANISM_COMMON: HUMAN;                                              
SOURCE  56 ORGANISM_TAXID: 9606;                                                
SOURCE  57 MOL_ID: 15;                                                          
SOURCE  58 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  59 ORGANISM_COMMON: HUMAN;                                              
SOURCE  60 ORGANISM_TAXID: 9606;                                                
SOURCE  61 MOL_ID: 16;                                                          
SOURCE  62 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  63 ORGANISM_COMMON: HUMAN;                                              
SOURCE  64 ORGANISM_TAXID: 9606;                                                
SOURCE  65 MOL_ID: 17;                                                          
SOURCE  66 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  67 ORGANISM_COMMON: HUMAN;                                              
SOURCE  68 ORGANISM_TAXID: 9606;                                                
SOURCE  69 MOL_ID: 18;                                                          
SOURCE  70 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  71 ORGANISM_COMMON: HUMAN;                                              
SOURCE  72 ORGANISM_TAXID: 9606;                                                
SOURCE  73 MOL_ID: 19;                                                          
SOURCE  74 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  75 ORGANISM_COMMON: HUMAN;                                              
SOURCE  76 ORGANISM_TAXID: 9606;                                                
SOURCE  77 MOL_ID: 20;                                                          
SOURCE  78 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  79 ORGANISM_COMMON: HUMAN;                                              
SOURCE  80 ORGANISM_TAXID: 9606;                                                
SOURCE  81 MOL_ID: 21;                                                          
SOURCE  82 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  83 ORGANISM_COMMON: HUMAN;                                              
SOURCE  84 ORGANISM_TAXID: 9606;                                                
SOURCE  85 MOL_ID: 22;                                                          
SOURCE  86 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  87 ORGANISM_COMMON: HUMAN;                                              
SOURCE  88 ORGANISM_TAXID: 9606;                                                
SOURCE  89 MOL_ID: 23;                                                          
SOURCE  90 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  91 ORGANISM_COMMON: HUMAN;                                              
SOURCE  92 ORGANISM_TAXID: 9606;                                                
SOURCE  93 MOL_ID: 24;                                                          
SOURCE  94 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  95 ORGANISM_COMMON: HUMAN;                                              
SOURCE  96 ORGANISM_TAXID: 9606;                                                
SOURCE  97 MOL_ID: 25;                                                          
SOURCE  98 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  99 ORGANISM_COMMON: HUMAN;                                              
SOURCE 100 ORGANISM_TAXID: 9606;                                                
SOURCE 101 MOL_ID: 26;                                                          
SOURCE 102 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 103 ORGANISM_COMMON: HUMAN;                                              
SOURCE 104 ORGANISM_TAXID: 9606;                                                
SOURCE 105 MOL_ID: 27;                                                          
SOURCE 106 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 107 ORGANISM_COMMON: HUMAN;                                              
SOURCE 108 ORGANISM_TAXID: 9606;                                                
SOURCE 109 MOL_ID: 28;                                                          
SOURCE 110 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 111 ORGANISM_COMMON: HUMAN;                                              
SOURCE 112 ORGANISM_TAXID: 9606;                                                
SOURCE 113 MOL_ID: 29;                                                          
SOURCE 114 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 115 ORGANISM_COMMON: HUMAN;                                              
SOURCE 116 ORGANISM_TAXID: 9606;                                                
SOURCE 117 MOL_ID: 30;                                                          
SOURCE 118 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 119 ORGANISM_COMMON: HUMAN;                                              
SOURCE 120 ORGANISM_TAXID: 9606;                                                
SOURCE 121 MOL_ID: 31;                                                          
SOURCE 122 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 123 ORGANISM_COMMON: HUMAN;                                              
SOURCE 124 ORGANISM_TAXID: 9606;                                                
SOURCE 125 MOL_ID: 32;                                                          
SOURCE 126 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 127 ORGANISM_COMMON: HUMAN;                                              
SOURCE 128 ORGANISM_TAXID: 9606                                                 
KEYWDS    26S PROTEASOME, CRYO-EM, SINGLE PARTICLE ANALYSIS, HOMOLOGY           
KEYWDS   2 MODELLING, HYDROLASE                                                 
EXPDTA    ELECTRON MICROSCOPY                                                   
AUTHOR    A.SCHWEITZER,F.BECK,E.SAKATA,P.UNVERDORBEN                            
REVDAT   3   24-MAY-17 5LN3    1       JRNL                                     
REVDAT   2   12-APR-17 5LN3    1       JRNL                                     
REVDAT   1   22-MAR-17 5LN3    0                                                
JRNL        AUTH   X.WANG,P.CIMERMANCIC,C.YU,A.SCHWEITZER,N.CHOPRA,J.L.ENGEL,   
JRNL        AUTH 2 C.GREENBERG,A.S.HUSZAGH,F.BECK,E.SAKATA,Y.YANG,E.J.NOVITSKY, 
JRNL        AUTH 3 A.LEITNER,P.NANNI,A.KAHRAMAN,X.GUO,J.E.DIXON,S.D.RYCHNOVSKY, 
JRNL        AUTH 4 R.AEBERSOLD,W.BAUMEISTER,A.SALI,L.HUANG                      
JRNL        TITL   MOLECULAR DETAILS UNDERLYING DYNAMIC STRUCTURES AND          
JRNL        TITL 2 REGULATION OF THE HUMAN 26S PROTEASOME.                      
JRNL        REF    MOL. CELL PROTEOMICS          V.  16   840 2017              
JRNL        REFN                   ESSN 1535-9484                               
JRNL        PMID   28292943                                                     
JRNL        DOI    10.1074/MCP.M116.065326                                      
REMARK   2                                                                      
REMARK   2 RESOLUTION.    6.80 ANGSTROMS.                                       
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   SOFTWARE PACKAGES      : NULL                                      
REMARK   3   RECONSTRUCTION SCHEMA  : NULL                                      
REMARK   3                                                                      
REMARK   3 EM MAP-MODEL FITTING AND REFINEMENT                                  
REMARK   3   PDB ENTRY                    : NULL                                
REMARK   3   REFINEMENT SPACE             : REAL                                
REMARK   3   REFINEMENT PROTOCOL          : FLEXIBLE FIT                        
REMARK   3   REFINEMENT TARGET            : NULL                                
REMARK   3   OVERALL ANISOTROPIC B VALUE  : NULL                                
REMARK   3                                                                      
REMARK   3 FITTING PROCEDURE : NULL                                             
REMARK   3                                                                      
REMARK   3 EM IMAGE RECONSTRUCTION STATISTICS                                   
REMARK   3   NOMINAL PIXEL SIZE (ANGSTROMS)    : NULL                           
REMARK   3   ACTUAL PIXEL SIZE  (ANGSTROMS)    : NULL                           
REMARK   3   EFFECTIVE RESOLUTION (ANGSTROMS)  : 6.800                          
REMARK   3   NUMBER OF PARTICLES               : 252000                         
REMARK   3   CTF CORRECTION METHOD             : PHASE FLIPPING AND AMPLITUDE   
REMARK   3                                       CORRECTION                     
REMARK   3                                                                      
REMARK   3 EM RECONSTRUCTION MAGNIFICATION CALIBRATION: NULL                    
REMARK   3                                                                      
REMARK   3 OTHER DETAILS: NULL                                                  
REMARK   4                                                                      
REMARK   4 5LN3 COMPLIES WITH FORMAT V. 3.30, 13-JUL-11                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBE ON 03-AUG-16.                  
REMARK 100 THE DEPOSITION ID IS D_1200001017.                                   
REMARK 245                                                                      
REMARK 245 EXPERIMENTAL DETAILS                                                 
REMARK 245   RECONSTRUCTION METHOD          : SINGLE PARTICLE                   
REMARK 245   SPECIMEN TYPE                  : NULL                              
REMARK 245                                                                      
REMARK 245 ELECTRON MICROSCOPE SAMPLE                                           
REMARK 245   SAMPLE TYPE                    : PARTICLE                          
REMARK 245   PARTICLE TYPE                  : POINT                             
REMARK 245   NAME OF SAMPLE                 : HUMAN 26S PROTEASOME              
REMARK 245   SAMPLE CONCENTRATION (MG ML-1) : 0.50                              
REMARK 245   SAMPLE SUPPORT DETAILS         : NULL                              
REMARK 245   SAMPLE VITRIFICATION DETAILS   : NULL                              
REMARK 245   SAMPLE BUFFER                  : NULL                              
REMARK 245   PH                             : 7.50                              
REMARK 245   SAMPLE DETAILS                 : NULL                              
REMARK 245                                                                      
REMARK 245 DATA ACQUISITION                                                     
REMARK 245   DATE OF EXPERIMENT                : NULL                           
REMARK 245   NUMBER OF MICROGRAPHS-IMAGES      : 31857                          
REMARK 245   TEMPERATURE (KELVIN)              : NULL                           
REMARK 245   MICROSCOPE MODEL                  : FEI TITAN KRIOS                
REMARK 245   DETECTOR TYPE                     : FEI FALCON II (4K X 4K)        
REMARK 245   MINIMUM DEFOCUS (NM)              : 800.00                         
REMARK 245   MAXIMUM DEFOCUS (NM)              : 3500.00                        
REMARK 245   MINIMUM TILT ANGLE (DEGREES)      : NULL                           
REMARK 245   MAXIMUM TILT ANGLE (DEGREES)      : NULL                           
REMARK 245   NOMINAL CS                        : NULL                           
REMARK 245   IMAGING MODE                      : BRIGHT FIELD                   
REMARK 245   ELECTRON DOSE (ELECTRONS NM**-2)  : 45.00                          
REMARK 245   ILLUMINATION MODE                 : FLOOD BEAM                     
REMARK 245   NOMINAL MAGNIFICATION             : NULL                           
REMARK 245   CALIBRATED MAGNIFICATION          : NULL                           
REMARK 245   SOURCE                            : FIELD EMISSION GUN             
REMARK 245   ACCELERATION VOLTAGE (KV)         : 300                            
REMARK 245   IMAGING DETAILS                   : NULL                           
REMARK 247                                                                      
REMARK 247 ELECTRON MICROSCOPY                                                  
REMARK 247  THE COORDINATES IN THIS ENTRY WERE GENERATED FROM ELECTRON          
REMARK 247  MICROSCOPY DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE              
REMARK 247  THAT CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES           
REMARK 247  ON THESE RECORDS ARE MEANINGLESS EXCEPT FOR THE CALCULATION         
REMARK 247  OF THE STRUCTURE FACTORS.                                           
REMARK 300                                                                      
REMARK 300 BIOMOLECULE: 1                                                       
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM                
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN                  
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON               
REMARK 300 BURIED SURFACE AREA.                                                 
REMARK 350                                                                      
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN           
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE                
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS          
REMARK 350 GIVEN BELOW.  BOTH NON-CRYSTALLOGRAPHIC AND                          
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.                               
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 1                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: 32-MERIC                          
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: 32-MERIC                   
REMARK 350 SOFTWARE USED: PISA                                                  
REMARK 350 TOTAL BURIED SURFACE AREA: 141740 ANGSTROM**2                        
REMARK 350 SURFACE AREA OF THE COMPLEX: 435060 ANGSTROM**2                      
REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -607.0 KCAL/MOL                       
REMARK 350 APPLY THE FOLLOWING TO CHAINS: Z, 1, 2, 3, 4, 5, 6, 7, A, B,         
REMARK 350                    AND CHAINS: C, D, E, F, G, H, I, J, K,            
REMARK 350                    AND CHAINS: L, M, N, O, P, Q, R, S, T, U,         
REMARK 350                    AND CHAINS: V, W, Y                               
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 465                                                                      
REMARK 465 MISSING RESIDUES                                                     
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE                       
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)                
REMARK 465                                                                      
REMARK 465   M RES C SSSEQI                                                     
REMARK 465     MET Z     1                                                      
REMARK 465     GLU Z     2                                                      
REMARK 465     GLU Z     3                                                      
REMARK 465     GLY Z     4                                                      
REMARK 465     GLY Z     5                                                      
REMARK 465     ARG Z     6                                                      
REMARK 465     ASP Z     7                                                      
REMARK 465     LYS Z     8                                                      
REMARK 465     ALA Z     9                                                      
REMARK 465     PRO Z    10                                                      
REMARK 465     VAL Z    11                                                      
REMARK 465     GLN Z    12                                                      
REMARK 465     PRO Z    13                                                      
REMARK 465     GLN Z    14                                                      
REMARK 465     GLN Z    15                                                      
REMARK 465     SER Z    16                                                      
REMARK 465     PRO Z    17                                                      
REMARK 465     ALA Z    18                                                      
REMARK 465     ALA Z    19                                                      
REMARK 465     ALA Z    20                                                      
REMARK 465     PRO Z    21                                                      
REMARK 465     GLY Z    22                                                      
REMARK 465     GLY Z    23                                                      
REMARK 465     THR Z    24                                                      
REMARK 465     ASP Z    25                                                      
REMARK 465     GLU Z    26                                                      
REMARK 465     LYS Z    27                                                      
REMARK 465     PRO Z    28                                                      
REMARK 465     SER Z    29                                                      
REMARK 465     GLY Z    30                                                      
REMARK 465     LYS Z    31                                                      
REMARK 465     GLU Z    32                                                      
REMARK 465     ARG Z    33                                                      
REMARK 465     ARG Z    34                                                      
REMARK 465     ASP Z    35                                                      
REMARK 465     ALA Z    36                                                      
REMARK 465     GLY Z    37                                                      
REMARK 465     ASP Z    38                                                      
REMARK 465     LYS Z    39                                                      
REMARK 465     ASP Z    40                                                      
REMARK 465     LYS Z    41                                                      
REMARK 465     GLU Z    42                                                      
REMARK 465     GLN Z    43                                                      
REMARK 465     GLU Z    44                                                      
REMARK 465     LEU Z    45                                                      
REMARK 465     SER Z    46                                                      
REMARK 465     GLU Z    47                                                      
REMARK 465     GLU Z    48                                                      
REMARK 465     ASP Z    49                                                      
REMARK 465     LYS Z    50                                                      
REMARK 465     GLN Z    51                                                      
REMARK 465     LEU Z    52                                                      
REMARK 465     GLN Z    53                                                      
REMARK 465     ASP Z    54                                                      
REMARK 465     GLU Z    55                                                      
REMARK 465     LEU Z    56                                                      
REMARK 465     GLU Z    57                                                      
REMARK 465     GLU Z   618                                                      
REMARK 465     HIS Z   619                                                      
REMARK 465     PHE Z   620                                                      
REMARK 465     ASP Z   621                                                      
REMARK 465     SER Z   622                                                      
REMARK 465     LYS Z   623                                                      
REMARK 465     GLU Z   624                                                      
REMARK 465     LYS Z   625                                                      
REMARK 465     GLU Z   626                                                      
REMARK 465     GLU Z   627                                                      
REMARK 465     ASP Z   628                                                      
REMARK 465     LYS Z   629                                                      
REMARK 465     ASP Z   630                                                      
REMARK 465     LYS Z   631                                                      
REMARK 465     LYS Z   632                                                      
REMARK 465     GLU Z   633                                                      
REMARK 465     LYS Z   634                                                      
REMARK 465     LYS Z   635                                                      
REMARK 465     ASP Z   636                                                      
REMARK 465     LYS Z   637                                                      
REMARK 465     ASP Z   638                                                      
REMARK 465     LYS Z   639                                                      
REMARK 465     LYS Z   640                                                      
REMARK 465     GLU Z   641                                                      
REMARK 465     ALA Z   642                                                      
REMARK 465     PRO Z   643                                                      
REMARK 465     ALA Z   644                                                      
REMARK 465     ASP Z   645                                                      
REMARK 465     MET Z   646                                                      
REMARK 465     GLY Z   647                                                      
REMARK 465     ALA Z   648                                                      
REMARK 465     HIS Z   649                                                      
REMARK 465     GLY Z   847                                                      
REMARK 465     GLN Z   848                                                      
REMARK 465     ALA Z   849                                                      
REMARK 465     VAL Z   850                                                      
REMARK 465     ASP Z   851                                                      
REMARK 465     VAL Z   852                                                      
REMARK 465     VAL Z   853                                                      
REMARK 465     GLY Z   854                                                      
REMARK 465     GLN Z   855                                                      
REMARK 465     ALA Z   856                                                      
REMARK 465     GLY Z   857                                                      
REMARK 465     LYS Z   858                                                      
REMARK 465     PRO Z   859                                                      
REMARK 465     LYS Z   860                                                      
REMARK 465     THR Z   861                                                      
REMARK 465     ILE Z   862                                                      
REMARK 465     THR Z   863                                                      
REMARK 465     GLY Z   864                                                      
REMARK 465     PHE Z   865                                                      
REMARK 465     GLN Z   866                                                      
REMARK 465     THR Z   867                                                      
REMARK 465     HIS Z   868                                                      
REMARK 465     THR Z   869                                                      
REMARK 465     THR Z   870                                                      
REMARK 465     PRO Z   871                                                      
REMARK 465     MET 1     1                                                      
REMARK 465     ALA 1     2                                                      
REMARK 465     ALA 1     3                                                      
REMARK 465     THR 1     4                                                      
REMARK 465     LEU 1     5                                                      
REMARK 465     LEU 1     6                                                      
REMARK 465     ALA 1     7                                                      
REMARK 465     ALA 1     8                                                      
REMARK 465     ARG 1     9                                                      
REMARK 465     GLY 1    10                                                      
REMARK 465     ALA 1    11                                                      
REMARK 465     GLY 1    12                                                      
REMARK 465     PRO 1    13                                                      
REMARK 465     ALA 1    14                                                      
REMARK 465     PRO 1    15                                                      
REMARK 465     ALA 1    16                                                      
REMARK 465     TRP 1    17                                                      
REMARK 465     GLY 1    18                                                      
REMARK 465     PRO 1    19                                                      
REMARK 465     GLU 1    20                                                      
REMARK 465     ALA 1    21                                                      
REMARK 465     PHE 1    22                                                      
REMARK 465     THR 1    23                                                      
REMARK 465     PRO 1    24                                                      
REMARK 465     ASP 1    25                                                      
REMARK 465     MET 2     1                                                      
REMARK 465     ALA 2     2                                                      
REMARK 465     ALA 2     3                                                      
REMARK 465     VAL 2     4                                                      
REMARK 465     SER 2     5                                                      
REMARK 465     VAL 2     6                                                      
REMARK 465     TYR 2     7                                                      
REMARK 465     ALA 2     8                                                      
REMARK 465     PRO 2     9                                                      
REMARK 465     PRO 2    10                                                      
REMARK 465     VAL 2    11                                                      
REMARK 465     GLY 2    12                                                      
REMARK 465     GLY 2    13                                                      
REMARK 465     PHE 2    14                                                      
REMARK 465     SER 2    15                                                      
REMARK 465     PHE 2    16                                                      
REMARK 465     ASP 2    17                                                      
REMARK 465     ASN 2    18                                                      
REMARK 465     CYS 2    19                                                      
REMARK 465     ARG 2    20                                                      
REMARK 465     ARG 2    21                                                      
REMARK 465     ASN 2    22                                                      
REMARK 465     ALA 2    23                                                      
REMARK 465     VAL 2    24                                                      
REMARK 465     LEU 2    25                                                      
REMARK 465     GLU 2    26                                                      
REMARK 465     ALA 2    27                                                      
REMARK 465     ASP 2    28                                                      
REMARK 465     PHE 2    29                                                      
REMARK 465     ALA 2    30                                                      
REMARK 465     LYS 2    31                                                      
REMARK 465     ARG 2    32                                                      
REMARK 465     GLY 2    33                                                      
REMARK 465     TYR 2    34                                                      
REMARK 465     LYS 2    35                                                      
REMARK 465     LEU 2    36                                                      
REMARK 465     PRO 2    37                                                      
REMARK 465     LYS 2    38                                                      
REMARK 465     VAL 2    39                                                      
REMARK 465     ARG 2    40                                                      
REMARK 465     LYS 2    41                                                      
REMARK 465     THR 2    42                                                      
REMARK 465     GLY 2    43                                                      
REMARK 465     VAL 2   266                                                      
REMARK 465     LEU 2   267                                                      
REMARK 465     GLU 2   268                                                      
REMARK 465     GLU 2   269                                                      
REMARK 465     THR 2   270                                                      
REMARK 465     VAL 2   271                                                      
REMARK 465     GLN 2   272                                                      
REMARK 465     THR 2   273                                                      
REMARK 465     MET 2   274                                                      
REMARK 465     ASP 2   275                                                      
REMARK 465     THR 2   276                                                      
REMARK 465     SER 2   277                                                      
REMARK 465     SER 4   195                                                      
REMARK 465     PHE 4   196                                                      
REMARK 465     PRO 4   197                                                      
REMARK 465     LYS 4   198                                                      
REMARK 465     GLN 4   199                                                      
REMARK 465     GLY 4   200                                                      
REMARK 465     SER 4   201                                                      
REMARK 465     MET 5     1                                                      
REMARK 465     ALA 5     2                                                      
REMARK 465     LEU 5     3                                                      
REMARK 465     ALA 5     4                                                      
REMARK 465     SER 5     5                                                      
REMARK 465     VAL 5     6                                                      
REMARK 465     LEU 5     7                                                      
REMARK 465     GLU 5     8                                                      
REMARK 465     ARG 5     9                                                      
REMARK 465     PRO 5    10                                                      
REMARK 465     LEU 5    11                                                      
REMARK 465     PRO 5    12                                                      
REMARK 465     VAL 5    13                                                      
REMARK 465     ASN 5    14                                                      
REMARK 465     GLN 5    15                                                      
REMARK 465     ARG 5    16                                                      
REMARK 465     GLY 5    17                                                      
REMARK 465     PHE 5    18                                                      
REMARK 465     PHE 5    19                                                      
REMARK 465     GLY 5    20                                                      
REMARK 465     LEU 5    21                                                      
REMARK 465     GLY 5    22                                                      
REMARK 465     GLY 5    23                                                      
REMARK 465     ARG 5    24                                                      
REMARK 465     ALA 5    25                                                      
REMARK 465     ASP 5    26                                                      
REMARK 465     LEU 5    27                                                      
REMARK 465     LEU 5    28                                                      
REMARK 465     ASP 5    29                                                      
REMARK 465     LEU 5    30                                                      
REMARK 465     GLY 5    31                                                      
REMARK 465     PRO 5    32                                                      
REMARK 465     GLY 5    33                                                      
REMARK 465     SER 5    34                                                      
REMARK 465     LEU 5    35                                                      
REMARK 465     SER 5    36                                                      
REMARK 465     ASP 5    37                                                      
REMARK 465     GLY 5    38                                                      
REMARK 465     LEU 5    39                                                      
REMARK 465     SER 5    40                                                      
REMARK 465     LEU 5    41                                                      
REMARK 465     ALA 5    42                                                      
REMARK 465     ALA 5    43                                                      
REMARK 465     PRO 5    44                                                      
REMARK 465     GLY 5    45                                                      
REMARK 465     TRP 5    46                                                      
REMARK 465     GLY 5    47                                                      
REMARK 465     VAL 5    48                                                      
REMARK 465     PRO 5    49                                                      
REMARK 465     GLU 5    50                                                      
REMARK 465     GLU 5    51                                                      
REMARK 465     PRO 5    52                                                      
REMARK 465     GLY 5    53                                                      
REMARK 465     ILE 5    54                                                      
REMARK 465     GLU 5    55                                                      
REMARK 465     MET 5    56                                                      
REMARK 465     LEU 5    57                                                      
REMARK 465     HIS 5    58                                                      
REMARK 465     GLY 5    59                                                      
REMARK 465     HIS 5   255                                                      
REMARK 465     GLU 5   256                                                      
REMARK 465     LYS 5   257                                                      
REMARK 465     TYR 5   258                                                      
REMARK 465     SER 5   259                                                      
REMARK 465     GLY 5   260                                                      
REMARK 465     SER 5   261                                                      
REMARK 465     THR 5   262                                                      
REMARK 465     PRO 5   263                                                      
REMARK 465     MET 6     1                                                      
REMARK 465     LEU 6     2                                                      
REMARK 465     SER 6     3                                                      
REMARK 465     SER 6     4                                                      
REMARK 465     THR 6     5                                                      
REMARK 465     ALA 6     6                                                      
REMARK 465     MET 6     7                                                      
REMARK 465     TYR 6     8                                                      
REMARK 465     SER 6     9                                                      
REMARK 465     ALA 6    10                                                      
REMARK 465     PRO 6    11                                                      
REMARK 465     GLY 6    12                                                      
REMARK 465     ARG 6    13                                                      
REMARK 465     ASP 6    14                                                      
REMARK 465     LEU 6    15                                                      
REMARK 465     GLY 6    16                                                      
REMARK 465     MET 6    17                                                      
REMARK 465     GLU 6    18                                                      
REMARK 465     PRO 6    19                                                      
REMARK 465     HIS 6    20                                                      
REMARK 465     ARG 6    21                                                      
REMARK 465     ALA 6    22                                                      
REMARK 465     ALA 6    23                                                      
REMARK 465     GLY 6    24                                                      
REMARK 465     PRO 6    25                                                      
REMARK 465     LEU 6    26                                                      
REMARK 465     GLN 6    27                                                      
REMARK 465     LEU 6    28                                                      
REMARK 465     MET 7     1                                                      
REMARK 465     GLU 7     2                                                      
REMARK 465     ALA 7     3                                                      
REMARK 465     PHE 7     4                                                      
REMARK 465     LEU 7     5                                                      
REMARK 465     GLY 7     6                                                      
REMARK 465     SER 7     7                                                      
REMARK 465     ARG 7     8                                                      
REMARK 465     SER 7     9                                                      
REMARK 465     GLY 7    10                                                      
REMARK 465     LEU 7    11                                                      
REMARK 465     TRP 7    12                                                      
REMARK 465     ALA 7    13                                                      
REMARK 465     GLY 7    14                                                      
REMARK 465     GLY 7    15                                                      
REMARK 465     PRO 7    16                                                      
REMARK 465     ALA 7    17                                                      
REMARK 465     PRO 7    18                                                      
REMARK 465     GLY 7    19                                                      
REMARK 465     GLN 7    20                                                      
REMARK 465     PHE 7    21                                                      
REMARK 465     TYR 7    22                                                      
REMARK 465     ARG 7    23                                                      
REMARK 465     ILE 7    24                                                      
REMARK 465     PRO 7    25                                                      
REMARK 465     SER 7    26                                                      
REMARK 465     THR 7    27                                                      
REMARK 465     PRO 7    28                                                      
REMARK 465     ASP 7    29                                                      
REMARK 465     SER 7    30                                                      
REMARK 465     PHE 7    31                                                      
REMARK 465     MET 7    32                                                      
REMARK 465     ASP 7    33                                                      
REMARK 465     PRO 7    34                                                      
REMARK 465     ALA 7    35                                                      
REMARK 465     SER 7    36                                                      
REMARK 465     ALA 7    37                                                      
REMARK 465     LEU 7    38                                                      
REMARK 465     TYR 7    39                                                      
REMARK 465     ARG 7    40                                                      
REMARK 465     GLY 7    41                                                      
REMARK 465     PRO 7    42                                                      
REMARK 465     ILE 7    43                                                      
REMARK 465     THR 7    44                                                      
REMARK 465     ARG 7    45                                                      
REMARK 465     THR 7    46                                                      
REMARK 465     MET A     1                                                      
REMARK 465     SER A     2                                                      
REMARK 465     ARG A     3                                                      
REMARK 465     GLY A     4                                                      
REMARK 465     SER A     5                                                      
REMARK 465     SER A     6                                                      
REMARK 465     ALA A     7                                                      
REMARK 465     MET E     1                                                      
REMARK 465     PHE E     2                                                      
REMARK 465     LEU E     3                                                      
REMARK 465     THR E     4                                                      
REMARK 465     ARG E     5                                                      
REMARK 465     SER E     6                                                      
REMARK 465     GLU E     7                                                      
REMARK 465     TYR E     8                                                      
REMARK 465     ASP E     9                                                      
REMARK 465     GLU F   234                                                      
REMARK 465     GLY F   235                                                      
REMARK 465     LEU F   236                                                      
REMARK 465     GLU F   237                                                      
REMARK 465     GLU F   238                                                      
REMARK 465     ARG F   239                                                      
REMARK 465     PRO F   240                                                      
REMARK 465     GLN F   241                                                      
REMARK 465     ARG F   242                                                      
REMARK 465     LYS F   243                                                      
REMARK 465     ALA F   244                                                      
REMARK 465     GLN F   245                                                      
REMARK 465     PRO F   246                                                      
REMARK 465     ALA F   247                                                      
REMARK 465     GLN F   248                                                      
REMARK 465     PRO F   249                                                      
REMARK 465     ALA F   250                                                      
REMARK 465     ASP F   251                                                      
REMARK 465     GLU F   252                                                      
REMARK 465     PRO F   253                                                      
REMARK 465     ALA F   254                                                      
REMARK 465     GLU F   255                                                      
REMARK 465     LYS F   256                                                      
REMARK 465     ALA F   257                                                      
REMARK 465     ASP F   258                                                      
REMARK 465     GLU F   259                                                      
REMARK 465     PRO F   260                                                      
REMARK 465     MET F   261                                                      
REMARK 465     GLU F   262                                                      
REMARK 465     HIS F   263                                                      
REMARK 465     MET G     1                                                      
REMARK 465     SER G     2                                                      
REMARK 465     SER G     3                                                      
REMARK 465     ILE G     4                                                      
REMARK 465     GLU G   247                                                      
REMARK 465     ASP G   248                                                      
REMARK 465     GLU G   249                                                      
REMARK 465     SER G   250                                                      
REMARK 465     ASP G   251                                                      
REMARK 465     ASP G   252                                                      
REMARK 465     ASP G   253                                                      
REMARK 465     ASN G   254                                                      
REMARK 465     MET G   255                                                      
REMARK 465     MET H     1                                                      
REMARK 465     PRO H     2                                                      
REMARK 465     ASP H     3                                                      
REMARK 465     TYR H     4                                                      
REMARK 465     LEU H     5                                                      
REMARK 465     GLY H     6                                                      
REMARK 465     ALA H     7                                                      
REMARK 465     ASP H     8                                                      
REMARK 465     GLN H     9                                                      
REMARK 465     ARG H    10                                                      
REMARK 465     LYS H    11                                                      
REMARK 465     THR H    12                                                      
REMARK 465     LYS H    13                                                      
REMARK 465     GLU H    14                                                      
REMARK 465     ASP H    15                                                      
REMARK 465     GLU H    16                                                      
REMARK 465     LYS H    17                                                      
REMARK 465     ASP H    18                                                      
REMARK 465     ASP H    19                                                      
REMARK 465     LYS H    20                                                      
REMARK 465     PRO H    21                                                      
REMARK 465     ILE H    22                                                      
REMARK 465     ARG H    23                                                      
REMARK 465     ALA H    24                                                      
REMARK 465     LEU H    25                                                      
REMARK 465     ASP H    26                                                      
REMARK 465     GLU H    27                                                      
REMARK 465     GLY H    28                                                      
REMARK 465     ASP H    29                                                      
REMARK 465     ILE H    30                                                      
REMARK 465     ALA H    31                                                      
REMARK 465     LEU H    32                                                      
REMARK 465     LEU H    33                                                      
REMARK 465     LYS H    34                                                      
REMARK 465     THR H    35                                                      
REMARK 465     TYR H    36                                                      
REMARK 465     GLY H    37                                                      
REMARK 465     GLN H    38                                                      
REMARK 465     SER H    39                                                      
REMARK 465     THR H    40                                                      
REMARK 465     TYR H    41                                                      
REMARK 465     SER H    42                                                      
REMARK 465     ARG H    43                                                      
REMARK 465     GLN H    44                                                      
REMARK 465     PHE H   423                                                      
REMARK 465     SER H   424                                                      
REMARK 465     ALA H   425                                                      
REMARK 465     THR H   426                                                      
REMARK 465     PRO H   427                                                      
REMARK 465     ARG H   428                                                      
REMARK 465     TYR H   429                                                      
REMARK 465     MET H   430                                                      
REMARK 465     THR H   431                                                      
REMARK 465     TYR H   432                                                      
REMARK 465     ASN H   433                                                      
REMARK 465     MET I     1                                                      
REMARK 465     GLY I     2                                                      
REMARK 465     GLN I     3                                                      
REMARK 465     SER I     4                                                      
REMARK 465     GLN I     5                                                      
REMARK 465     SER I     6                                                      
REMARK 465     GLY I     7                                                      
REMARK 465     GLY I     8                                                      
REMARK 465     HIS I     9                                                      
REMARK 465     GLY I    10                                                      
REMARK 465     PRO I    11                                                      
REMARK 465     GLY I    12                                                      
REMARK 465     GLY I    13                                                      
REMARK 465     GLY I    14                                                      
REMARK 465     LYS I    15                                                      
REMARK 465     LYS I    16                                                      
REMARK 465     ASP I    17                                                      
REMARK 465     ASP I    18                                                      
REMARK 465     LYS I    19                                                      
REMARK 465     ASP I    20                                                      
REMARK 465     LYS I    21                                                      
REMARK 465     LYS I    22                                                      
REMARK 465     LYS I    23                                                      
REMARK 465     LYS I    24                                                      
REMARK 465     TYR I    25                                                      
REMARK 465     GLU I    26                                                      
REMARK 465     PRO I    27                                                      
REMARK 465     PRO I    28                                                      
REMARK 465     VAL I    29                                                      
REMARK 465     PRO I    30                                                      
REMARK 465     THR I    31                                                      
REMARK 465     ARG I    32                                                      
REMARK 465     VAL I    33                                                      
REMARK 465     GLY I    34                                                      
REMARK 465     LYS I    35                                                      
REMARK 465     LYS I    36                                                      
REMARK 465     LYS I    37                                                      
REMARK 465     LYS I    38                                                      
REMARK 465     LYS I    39                                                      
REMARK 465     THR I    40                                                      
REMARK 465     LYS I    41                                                      
REMARK 465     GLY I    42                                                      
REMARK 465     PRO I    43                                                      
REMARK 465     ASP I    44                                                      
REMARK 465     ALA I    45                                                      
REMARK 465     ALA I    46                                                      
REMARK 465     SER I    47                                                      
REMARK 465     LYS I    48                                                      
REMARK 465     LEU I    49                                                      
REMARK 465     PRO I    50                                                      
REMARK 465     LEU I    51                                                      
REMARK 465     VAL I    52                                                      
REMARK 465     THR I    53                                                      
REMARK 465     PRO I    54                                                      
REMARK 465     HIS I    55                                                      
REMARK 465     THR I    56                                                      
REMARK 465     GLN I    57                                                      
REMARK 465     CYS I    58                                                      
REMARK 465     ARG I    59                                                      
REMARK 465     LEU I    60                                                      
REMARK 465     LYS I    61                                                      
REMARK 465     LEU I    62                                                      
REMARK 465     LEU I    63                                                      
REMARK 465     LYS I    64                                                      
REMARK 465     LEU I    65                                                      
REMARK 465     GLU I    66                                                      
REMARK 465     ARG I    67                                                      
REMARK 465     ILE I    68                                                      
REMARK 465     LYS I    69                                                      
REMARK 465     ASP I    70                                                      
REMARK 465     TYR I    71                                                      
REMARK 465     LEU I    72                                                      
REMARK 465     LEU I    73                                                      
REMARK 465     MET I    74                                                      
REMARK 465     GLU I    75                                                      
REMARK 465     GLU I    76                                                      
REMARK 465     GLU I    77                                                      
REMARK 465     PHE I    78                                                      
REMARK 465     MET J     1                                                      
REMARK 465     ALA J     2                                                      
REMARK 465     LEU J     3                                                      
REMARK 465     ASP J     4                                                      
REMARK 465     GLY J     5                                                      
REMARK 465     PRO J     6                                                      
REMARK 465     GLU J     7                                                      
REMARK 465     GLN J     8                                                      
REMARK 465     MET J     9                                                      
REMARK 465     GLU J    10                                                      
REMARK 465     LEU J    11                                                      
REMARK 465     GLU J    12                                                      
REMARK 465     GLU J    13                                                      
REMARK 465     GLY J    14                                                      
REMARK 465     LYS J    15                                                      
REMARK 465     ALA J    16                                                      
REMARK 465     GLY J    17                                                      
REMARK 465     SER J    18                                                      
REMARK 465     GLY J    19                                                      
REMARK 465     LEU J    20                                                      
REMARK 465     ARG J    21                                                      
REMARK 465     GLN J    22                                                      
REMARK 465     TYR J    23                                                      
REMARK 465     TYR J    24                                                      
REMARK 465     ASN J   398                                                      
REMARK 465     MET J   399                                                      
REMARK 465     SER J   400                                                      
REMARK 465     ILE J   401                                                      
REMARK 465     LYS J   402                                                      
REMARK 465     LYS J   403                                                      
REMARK 465     LEU J   404                                                      
REMARK 465     TRP J   405                                                      
REMARK 465     LYS J   406                                                      
REMARK 465     MET K     1                                                      
REMARK 465     GLU K     2                                                      
REMARK 465     GLU K     3                                                      
REMARK 465     ILE K     4                                                      
REMARK 465     GLY K     5                                                      
REMARK 465     ILE K     6                                                      
REMARK 465     LEU K     7                                                      
REMARK 465     VAL K     8                                                      
REMARK 465     GLU K     9                                                      
REMARK 465     LYS K    10                                                      
REMARK 465     ALA K    11                                                      
REMARK 465     GLN K    12                                                      
REMARK 465     ASP K    13                                                      
REMARK 465     GLU K    14                                                      
REMARK 465     ILE K    15                                                      
REMARK 465     PRO K    16                                                      
REMARK 465     ALA K    17                                                      
REMARK 465     LEU K    18                                                      
REMARK 465     SER K    19                                                      
REMARK 465     VAL K    20                                                      
REMARK 465     SER K    21                                                      
REMARK 465     ARG K    22                                                      
REMARK 465     PRO K    23                                                      
REMARK 465     GLN K    24                                                      
REMARK 465     THR K    25                                                      
REMARK 465     GLY K    26                                                      
REMARK 465     LEU K    27                                                      
REMARK 465     SER K    28                                                      
REMARK 465     PHE K    29                                                      
REMARK 465     LEU K    30                                                      
REMARK 465     GLY K    31                                                      
REMARK 465     PRO K    32                                                      
REMARK 465     GLU K    33                                                      
REMARK 465     PRO K    34                                                      
REMARK 465     GLU K    35                                                      
REMARK 465     ASP K    36                                                      
REMARK 465     LEU K    37                                                      
REMARK 465     GLU K    38                                                      
REMARK 465     ASP K    39                                                      
REMARK 465     MET L     1                                                      
REMARK 465     ALA L     2                                                      
REMARK 465     ASP L     3                                                      
REMARK 465     PRO L     4                                                      
REMARK 465     ARG L     5                                                      
REMARK 465     ASP L     6                                                      
REMARK 465     LYS L     7                                                      
REMARK 465     ALA L     8                                                      
REMARK 465     LEU L     9                                                      
REMARK 465     GLN L    10                                                      
REMARK 465     ASP L    11                                                      
REMARK 465     TYR L    12                                                      
REMARK 465     ARG L    13                                                      
REMARK 465     LYS L    14                                                      
REMARK 465     LYS L    15                                                      
REMARK 465     LEU L    16                                                      
REMARK 465     LEU L    17                                                      
REMARK 465     GLU L    18                                                      
REMARK 465     LEU L   380                                                      
REMARK 465     GLU L   381                                                      
REMARK 465     SER L   382                                                      
REMARK 465     LYS L   383                                                      
REMARK 465     LEU L   384                                                      
REMARK 465     ASP L   385                                                      
REMARK 465     TYR L   386                                                      
REMARK 465     LYS L   387                                                      
REMARK 465     PRO L   388                                                      
REMARK 465     VAL L   389                                                      
REMARK 465     MET M     1                                                      
REMARK 465     ASN M     2                                                      
REMARK 465     LEU M     3                                                      
REMARK 465     LEU M     4                                                      
REMARK 465     PRO M     5                                                      
REMARK 465     ASN M     6                                                      
REMARK 465     ILE M     7                                                      
REMARK 465     GLU M     8                                                      
REMARK 465     SER M     9                                                      
REMARK 465     PRO M    10                                                      
REMARK 465     VAL M    11                                                      
REMARK 465     THR M    12                                                      
REMARK 465     ARG M    13                                                      
REMARK 465     GLN M    14                                                      
REMARK 465     GLU M    15                                                      
REMARK 465     LYS M    16                                                      
REMARK 465     MET M    17                                                      
REMARK 465     ALA M    18                                                      
REMARK 465     THR M    19                                                      
REMARK 465     VAL M    20                                                      
REMARK 465     TRP M    21                                                      
REMARK 465     ASP M    22                                                      
REMARK 465     GLU M    23                                                      
REMARK 465     ALA M    24                                                      
REMARK 465     GLU M    25                                                      
REMARK 465     GLN M    26                                                      
REMARK 465     ASP M    27                                                      
REMARK 465     GLY M    28                                                      
REMARK 465     ILE M    29                                                      
REMARK 465     GLY M    30                                                      
REMARK 465     GLU M    31                                                      
REMARK 465     GLU M    32                                                      
REMARK 465     VAL M    33                                                      
REMARK 465     LEU M    34                                                      
REMARK 465     LYS M    35                                                      
REMARK 465     MET M    36                                                      
REMARK 465     SER M    37                                                      
REMARK 465     THR M    38                                                      
REMARK 465     GLU M    39                                                      
REMARK 465     GLU M    40                                                      
REMARK 465     ILE M    41                                                      
REMARK 465     ILE M    42                                                      
REMARK 465     GLN M    43                                                      
REMARK 465     ARG M    44                                                      
REMARK 465     THR M    45                                                      
REMARK 465     ARG M    46                                                      
REMARK 465     LEU M    47                                                      
REMARK 465     LEU M    48                                                      
REMARK 465     ASP M    49                                                      
REMARK 465     SER M    50                                                      
REMARK 465     MET N     1                                                      
REMARK 465     ILE N     2                                                      
REMARK 465     ALA N   276                                                      
REMARK 465     SER N   277                                                      
REMARK 465     VAL N   278                                                      
REMARK 465     PRO N   279                                                      
REMARK 465     GLY N   280                                                      
REMARK 465     SER N   281                                                      
REMARK 465     THR N   282                                                      
REMARK 465     ASN N   283                                                      
REMARK 465     THR N   284                                                      
REMARK 465     GLY N   285                                                      
REMARK 465     THR N   286                                                      
REMARK 465     VAL N   287                                                      
REMARK 465     PRO N   288                                                      
REMARK 465     GLY N   289                                                      
REMARK 465     SER N   290                                                      
REMARK 465     GLU N   291                                                      
REMARK 465     LYS N   292                                                      
REMARK 465     ASP N   293                                                      
REMARK 465     SER N   294                                                      
REMARK 465     ASP N   295                                                      
REMARK 465     SER N   296                                                      
REMARK 465     MET N   297                                                      
REMARK 465     GLU N   298                                                      
REMARK 465     THR N   299                                                      
REMARK 465     GLU N   300                                                      
REMARK 465     GLU N   301                                                      
REMARK 465     LYS N   302                                                      
REMARK 465     THR N   303                                                      
REMARK 465     SER N   304                                                      
REMARK 465     SER N   305                                                      
REMARK 465     ALA N   306                                                      
REMARK 465     PHE N   307                                                      
REMARK 465     VAL N   308                                                      
REMARK 465     GLY N   309                                                      
REMARK 465     LYS N   310                                                      
REMARK 465     THR N   311                                                      
REMARK 465     PRO N   312                                                      
REMARK 465     GLU N   313                                                      
REMARK 465     ALA N   314                                                      
REMARK 465     SER N   315                                                      
REMARK 465     PRO N   316                                                      
REMARK 465     GLU N   317                                                      
REMARK 465     PRO N   318                                                      
REMARK 465     LYS N   319                                                      
REMARK 465     ASP N   320                                                      
REMARK 465     GLN N   321                                                      
REMARK 465     THR N   322                                                      
REMARK 465     LEU N   323                                                      
REMARK 465     LYS N   324                                                      
REMARK 465     MET N   325                                                      
REMARK 465     LEU N   817                                                      
REMARK 465     GLU N   818                                                      
REMARK 465     VAL N   819                                                      
REMARK 465     PRO N   820                                                      
REMARK 465     LYS N   821                                                      
REMARK 465     GLU N   822                                                      
REMARK 465     LYS N   823                                                      
REMARK 465     GLU N   824                                                      
REMARK 465     LYS N   825                                                      
REMARK 465     GLU N   826                                                      
REMARK 465     LYS N   827                                                      
REMARK 465     VAL N   828                                                      
REMARK 465     SER N   829                                                      
REMARK 465     THR N   830                                                      
REMARK 465     ALA N   831                                                      
REMARK 465     VAL N   832                                                      
REMARK 465     LEU N   833                                                      
REMARK 465     SER N   834                                                      
REMARK 465     ILE N   835                                                      
REMARK 465     THR N   836                                                      
REMARK 465     ALA N   837                                                      
REMARK 465     LYS N   838                                                      
REMARK 465     ALA N   839                                                      
REMARK 465     LYS N   840                                                      
REMARK 465     LYS N   841                                                      
REMARK 465     LYS N   842                                                      
REMARK 465     GLU N   843                                                      
REMARK 465     LYS N   844                                                      
REMARK 465     GLU N   845                                                      
REMARK 465     LYS N   846                                                      
REMARK 465     GLU N   847                                                      
REMARK 465     LYS N   848                                                      
REMARK 465     LYS N   849                                                      
REMARK 465     GLU N   850                                                      
REMARK 465     GLU N   851                                                      
REMARK 465     GLU N   852                                                      
REMARK 465     LYS N   853                                                      
REMARK 465     MET N   854                                                      
REMARK 465     GLU N   855                                                      
REMARK 465     VAL N   856                                                      
REMARK 465     ASP N   857                                                      
REMARK 465     GLU N   858                                                      
REMARK 465     ALA N   859                                                      
REMARK 465     GLU N   860                                                      
REMARK 465     LYS N   861                                                      
REMARK 465     LYS N   862                                                      
REMARK 465     GLU N   863                                                      
REMARK 465     GLU N   864                                                      
REMARK 465     LYS N   865                                                      
REMARK 465     GLU N   866                                                      
REMARK 465     GLU N   939                                                      
REMARK 465     GLN N   940                                                      
REMARK 465     GLU N   941                                                      
REMARK 465     PRO N   942                                                      
REMARK 465     GLU N   943                                                      
REMARK 465     PRO N   944                                                      
REMARK 465     PRO N   945                                                      
REMARK 465     GLU N   946                                                      
REMARK 465     PRO N   947                                                      
REMARK 465     PHE N   948                                                      
REMARK 465     GLU N   949                                                      
REMARK 465     TYR N   950                                                      
REMARK 465     ILE N   951                                                      
REMARK 465     ASP N   952                                                      
REMARK 465     ASP N   953                                                      
REMARK 465     MET P     1                                                      
REMARK 465     ALA P     2                                                      
REMARK 465     ASP P     3                                                      
REMARK 465     GLY P     4                                                      
REMARK 465     GLY P     5                                                      
REMARK 465     SER P     6                                                      
REMARK 465     GLU P     7                                                      
REMARK 465     ARG P     8                                                      
REMARK 465     ALA P     9                                                      
REMARK 465     ASP P    10                                                      
REMARK 465     GLY P    11                                                      
REMARK 465     ARG P    12                                                      
REMARK 465     ILE P    13                                                      
REMARK 465     VAL P    14                                                      
REMARK 465     LYS P    15                                                      
REMARK 465     MET P    16                                                      
REMARK 465     GLU P    17                                                      
REMARK 465     VAL P    18                                                      
REMARK 465     ASP P    19                                                      
REMARK 465     TYR P    20                                                      
REMARK 465     SER P    21                                                      
REMARK 465     ALA P    22                                                      
REMARK 465     THR P    23                                                      
REMARK 465     VAL P    24                                                      
REMARK 465     ASP P    25                                                      
REMARK 465     GLN P    26                                                      
REMARK 465     ARG P    27                                                      
REMARK 465     LEU P    28                                                      
REMARK 465     PRO P    29                                                      
REMARK 465     GLU P    30                                                      
REMARK 465     CYS P    31                                                      
REMARK 465     ALA P    32                                                      
REMARK 465     LYS P    33                                                      
REMARK 465     LEU P    34                                                      
REMARK 465     MET R     1                                                      
REMARK 465     PRO R     2                                                      
REMARK 465     LEU R     3                                                      
REMARK 465     GLU R     4                                                      
REMARK 465     ASN R     5                                                      
REMARK 465     LEU R     6                                                      
REMARK 465     GLU R     7                                                      
REMARK 465     GLU R     8                                                      
REMARK 465     GLU R     9                                                      
REMARK 465     GLY R    10                                                      
REMARK 465     LEU R    11                                                      
REMARK 465     PRO R    12                                                      
REMARK 465     LYS R    13                                                      
REMARK 465     ASN R    14                                                      
REMARK 465     PRO R    15                                                      
REMARK 465     MET S     1                                                      
REMARK 465     LYS S     2                                                      
REMARK 465     GLN S     3                                                      
REMARK 465     GLU S     4                                                      
REMARK 465     GLY S     5                                                      
REMARK 465     SER S     6                                                      
REMARK 465     ALA S     7                                                      
REMARK 465     ARG S     8                                                      
REMARK 465     ARG S     9                                                      
REMARK 465     ARG S    10                                                      
REMARK 465     GLY S    11                                                      
REMARK 465     ALA S    12                                                      
REMARK 465     ASP S    13                                                      
REMARK 465     LYS S    14                                                      
REMARK 465     ALA S    15                                                      
REMARK 465     LYS S    16                                                      
REMARK 465     PRO S    17                                                      
REMARK 465     PRO S    18                                                      
REMARK 465     PRO S    19                                                      
REMARK 465     GLY S    20                                                      
REMARK 465     GLY S    21                                                      
REMARK 465     GLY S    22                                                      
REMARK 465     GLU S    23                                                      
REMARK 465     GLN S    24                                                      
REMARK 465     GLU S    25                                                      
REMARK 465     PRO S    26                                                      
REMARK 465     PRO S    27                                                      
REMARK 465     PRO S    28                                                      
REMARK 465     PRO S    29                                                      
REMARK 465     PRO S    30                                                      
REMARK 465     ALA S    31                                                      
REMARK 465     PRO S    32                                                      
REMARK 465     GLN S    33                                                      
REMARK 465     ASP S    34                                                      
REMARK 465     VAL S    35                                                      
REMARK 465     GLU S    36                                                      
REMARK 465     MET S    37                                                      
REMARK 465     LYS S    38                                                      
REMARK 465     GLU S    39                                                      
REMARK 465     GLU S    40                                                      
REMARK 465     ALA S    41                                                      
REMARK 465     ALA S    42                                                      
REMARK 465     THR S    43                                                      
REMARK 465     GLY S    44                                                      
REMARK 465     GLY S    45                                                      
REMARK 465     GLY S    46                                                      
REMARK 465     SER S    47                                                      
REMARK 465     THR S    48                                                      
REMARK 465     GLY S    49                                                      
REMARK 465     GLU S    50                                                      
REMARK 465     ALA S    51                                                      
REMARK 465     ASP S    52                                                      
REMARK 465     GLY S    53                                                      
REMARK 465     LYS S    54                                                      
REMARK 465     THR S    55                                                      
REMARK 465     ALA S    56                                                      
REMARK 465     ALA S    57                                                      
REMARK 465     ALA S    58                                                      
REMARK 465     ALA S    59                                                      
REMARK 465     ALA S    60                                                      
REMARK 465     GLU S    61                                                      
REMARK 465     HIS S    62                                                      
REMARK 465     SER S    63                                                      
REMARK 465     GLN S    64                                                      
REMARK 465     ARG S    65                                                      
REMARK 465     GLU S    66                                                      
REMARK 465     LEU S    67                                                      
REMARK 465     ASP S    68                                                      
REMARK 465     THR S    69                                                      
REMARK 465     VAL S    70                                                      
REMARK 465     THR S    71                                                      
REMARK 465     LEU S    72                                                      
REMARK 465     GLU S    73                                                      
REMARK 465     ASP S    74                                                      
REMARK 465     ILE S    75                                                      
REMARK 465     LYS S    76                                                      
REMARK 465     GLU S    77                                                      
REMARK 465     HIS S    78                                                      
REMARK 465     VAL S    79                                                      
REMARK 465     LYS S    80                                                      
REMARK 465     GLN S    81                                                      
REMARK 465     LEU S    82                                                      
REMARK 465     GLU S    83                                                      
REMARK 465     LYS S    84                                                      
REMARK 465     ALA S    85                                                      
REMARK 465     VAL S    86                                                      
REMARK 465     SER S    87                                                      
REMARK 465     GLY S    88                                                      
REMARK 465     LYS S    89                                                      
REMARK 465     GLU S    90                                                      
REMARK 465     PRO S    91                                                      
REMARK 465     ARG S    92                                                      
REMARK 465     PHE S    93                                                      
REMARK 465     VAL S    94                                                      
REMARK 465     LEU S    95                                                      
REMARK 465     ARG S    96                                                      
REMARK 465     ALA S    97                                                      
REMARK 465     LEU S    98                                                      
REMARK 465     ARG S    99                                                      
REMARK 465     MET S   100                                                      
REMARK 465     LEU S   101                                                      
REMARK 465     PRO S   102                                                      
REMARK 465     SER S   103                                                      
REMARK 465     THR S   104                                                      
REMARK 465     SER S   105                                                      
REMARK 465     ARG S   106                                                      
REMARK 465     ARG S   107                                                      
REMARK 465     LEU S   108                                                      
REMARK 465     ASN S   109                                                      
REMARK 465     HIS S   110                                                      
REMARK 465     TYR S   111                                                      
REMARK 465     VAL S   112                                                      
REMARK 465     LEU S   113                                                      
REMARK 465     TYR S   114                                                      
REMARK 465     LYS S   115                                                      
REMARK 465     ALA S   116                                                      
REMARK 465     VAL S   117                                                      
REMARK 465     GLN S   118                                                      
REMARK 465     GLY S   119                                                      
REMARK 465     PHE S   120                                                      
REMARK 465     PHE S   121                                                      
REMARK 465     THR S   122                                                      
REMARK 465     SER S   123                                                      
REMARK 465     ASN S   124                                                      
REMARK 465     ASN S   125                                                      
REMARK 465     ALA S   126                                                      
REMARK 465     THR S   127                                                      
REMARK 465     ARG S   128                                                      
REMARK 465     ASP S   129                                                      
REMARK 465     PHE S   130                                                      
REMARK 465     LEU S   131                                                      
REMARK 465     LEU S   132                                                      
REMARK 465     PRO S   133                                                      
REMARK 465     PHE S   134                                                      
REMARK 465     LEU S   135                                                      
REMARK 465     GLU S   136                                                      
REMARK 465     GLU S   137                                                      
REMARK 465     PRO S   138                                                      
REMARK 465     MET S   139                                                      
REMARK 465     ASP S   140                                                      
REMARK 465     THR S   141                                                      
REMARK 465     GLU S   142                                                      
REMARK 465     ALA S   143                                                      
REMARK 465     ASP S   144                                                      
REMARK 465     LEU S   145                                                      
REMARK 465     GLN S   146                                                      
REMARK 465     PHE S   147                                                      
REMARK 465     ARG S   148                                                      
REMARK 465     PRO S   149                                                      
REMARK 465     ARG S   150                                                      
REMARK 465     THR S   151                                                      
REMARK 465     GLY S   152                                                      
REMARK 465     LYS S   153                                                      
REMARK 465     ALA S   154                                                      
REMARK 465     ALA S   155                                                      
REMARK 465     MET S   494                                                      
REMARK 465     ARG S   495                                                      
REMARK 465     PHE S   496                                                      
REMARK 465     PRO S   497                                                      
REMARK 465     PRO S   498                                                      
REMARK 465     LYS S   499                                                      
REMARK 465     SER S   500                                                      
REMARK 465     TYR S   501                                                      
REMARK 465     ASN S   502                                                      
REMARK 465     LYS S   503                                                      
REMARK 465     ASP S   504                                                      
REMARK 465     LEU S   505                                                      
REMARK 465     GLU S   506                                                      
REMARK 465     SER S   507                                                      
REMARK 465     ALA S   508                                                      
REMARK 465     GLU S   509                                                      
REMARK 465     GLU S   510                                                      
REMARK 465     ARG S   511                                                      
REMARK 465     ARG S   512                                                      
REMARK 465     GLU S   513                                                      
REMARK 465     ARG S   514                                                      
REMARK 465     GLU S   515                                                      
REMARK 465     GLN S   516                                                      
REMARK 465     GLN S   517                                                      
REMARK 465     ASP S   518                                                      
REMARK 465     LEU S   519                                                      
REMARK 465     GLU S   520                                                      
REMARK 465     PHE S   521                                                      
REMARK 465     ALA S   522                                                      
REMARK 465     LYS S   523                                                      
REMARK 465     GLU S   524                                                      
REMARK 465     MET S   525                                                      
REMARK 465     ALA S   526                                                      
REMARK 465     GLU S   527                                                      
REMARK 465     ASP S   528                                                      
REMARK 465     ASP S   529                                                      
REMARK 465     ASP S   530                                                      
REMARK 465     ASP S   531                                                      
REMARK 465     SER S   532                                                      
REMARK 465     PHE S   533                                                      
REMARK 465     PRO S   534                                                      
REMARK 465     MET T     1                                                      
REMARK 465     PHE T     2                                                      
REMARK 465     ILE T     3                                                      
REMARK 465     LYS T     4                                                      
REMARK 465     GLY T     5                                                      
REMARK 465     ARG T     6                                                      
REMARK 465     ALA T     7                                                      
REMARK 465     PRO T     8                                                      
REMARK 465     ARG T     9                                                      
REMARK 465     ALA T    10                                                      
REMARK 465     PRO T    11                                                      
REMARK 465     PRO T    12                                                      
REMARK 465     ARG T    13                                                      
REMARK 465     GLU T    14                                                      
REMARK 465     ARG T    15                                                      
REMARK 465     ARG T    16                                                      
REMARK 465     ARG T    17                                                      
REMARK 465     ALA T    18                                                      
REMARK 465     THR T    19                                                      
REMARK 465     ARG T    20                                                      
REMARK 465     GLY T    21                                                      
REMARK 465     GLY T    22                                                      
REMARK 465     LEU T    23                                                      
REMARK 465     ARG T    24                                                      
REMARK 465     GLN T    25                                                      
REMARK 465     VAL T    26                                                      
REMARK 465     VAL T    27                                                      
REMARK 465     ALA T    28                                                      
REMARK 465     PRO T    29                                                      
REMARK 465     PRO T    30                                                      
REMARK 465     ARG T    31                                                      
REMARK 465     ALA T    32                                                      
REMARK 465     LEU T    33                                                      
REMARK 465     GLY T    34                                                      
REMARK 465     SER T    35                                                      
REMARK 465     THR T    36                                                      
REMARK 465     SER T    37                                                      
REMARK 465     ARG T    38                                                      
REMARK 465     PRO T    39                                                      
REMARK 465     HIS T    40                                                      
REMARK 465     PHE T    41                                                      
REMARK 465     ARG T    42                                                      
REMARK 465     ARG T    43                                                      
REMARK 465     ALA T    44                                                      
REMARK 465     SER T    45                                                      
REMARK 465     VAL T    46                                                      
REMARK 465     CYS T    47                                                      
REMARK 465     ARG T    48                                                      
REMARK 465     ARG T    49                                                      
REMARK 465     ARG T    50                                                      
REMARK 465     CYS T    51                                                      
REMARK 465     ARG T    52                                                      
REMARK 465     LYS T    53                                                      
REMARK 465     SER T    54                                                      
REMARK 465     GLY T    55                                                      
REMARK 465     GLY T    56                                                      
REMARK 465     LEU T    57                                                      
REMARK 465     LEU T    58                                                      
REMARK 465     ASN T    70                                                      
REMARK 465     GLY T    71                                                      
REMARK 465     ALA T    72                                                      
REMARK 465     ALA T    73                                                      
REMARK 465     GLY T    74                                                      
REMARK 465     PHE T    75                                                      
REMARK 465     SER T    76                                                      
REMARK 465     SER T    77                                                      
REMARK 465     SER T    78                                                      
REMARK 465     GLY T    79                                                      
REMARK 465     PRO T    80                                                      
REMARK 465     ALA T    81                                                      
REMARK 465     ALA T    82                                                      
REMARK 465     THR T    83                                                      
REMARK 465     SER T    84                                                      
REMARK 465     GLY T    85                                                      
REMARK 465     ALA T    86                                                      
REMARK 465     VAL T    87                                                      
REMARK 465     LEU T    88                                                      
REMARK 465     GLN T    89                                                      
REMARK 465     ALA T    90                                                      
REMARK 465     ALA T    91                                                      
REMARK 465     THR T    92                                                      
REMARK 465     GLY T    93                                                      
REMARK 465     MET T    94                                                      
REMARK 465     TYR T    95                                                      
REMARK 465     GLU T    96                                                      
REMARK 465     GLN T    97                                                      
REMARK 465     LEU T    98                                                      
REMARK 465     LYS T    99                                                      
REMARK 465     GLY T   100                                                      
REMARK 465     GLU T   101                                                      
REMARK 465     TRP T   102                                                      
REMARK 465     ASN T   103                                                      
REMARK 465     ARG T   104                                                      
REMARK 465     LYS T   105                                                      
REMARK 465     SER T   106                                                      
REMARK 465     PRO T   107                                                      
REMARK 465     ASN T   108                                                      
REMARK 465     VAL U   144                                                      
REMARK 465     HIS U   145                                                      
REMARK 465     ASP U   146                                                      
REMARK 465     ASP U   147                                                      
REMARK 465     GLY U   148                                                      
REMARK 465     THR U   149                                                      
REMARK 465     PRO U   150                                                      
REMARK 465     THR U   151                                                      
REMARK 465     ARG U   177                                                      
REMARK 465     ASP U   178                                                      
REMARK 465     ILE U   179                                                      
REMARK 465     LYS U   180                                                      
REMARK 465     ASP U   181                                                      
REMARK 465     THR U   182                                                      
REMARK 465     THR U   183                                                      
REMARK 465     VAL U   184                                                      
REMARK 465     GLY U   185                                                      
REMARK 465     THR U   186                                                      
REMARK 465     LEU U   187                                                      
REMARK 465     SER U   188                                                      
REMARK 465     GLN U   189                                                      
REMARK 465     GLU U   294                                                      
REMARK 465     GLU U   295                                                      
REMARK 465     SER U   296                                                      
REMARK 465     LYS U   297                                                      
REMARK 465     LYS U   298                                                      
REMARK 465     ASP U   299                                                      
REMARK 465     ARG U   300                                                      
REMARK 465     LYS U   301                                                      
REMARK 465     GLU U   302                                                      
REMARK 465     ASP U   303                                                      
REMARK 465     LYS U   304                                                      
REMARK 465     GLU U   305                                                      
REMARK 465     LYS U   306                                                      
REMARK 465     ASP U   307                                                      
REMARK 465     LYS U   308                                                      
REMARK 465     ASP U   309                                                      
REMARK 465     LYS U   310                                                      
REMARK 465     GLU U   311                                                      
REMARK 465     LYS U   312                                                      
REMARK 465     SER U   313                                                      
REMARK 465     ASP U   314                                                      
REMARK 465     VAL U   315                                                      
REMARK 465     LYS U   316                                                      
REMARK 465     LYS U   317                                                      
REMARK 465     GLU U   318                                                      
REMARK 465     GLU U   319                                                      
REMARK 465     LYS U   320                                                      
REMARK 465     LYS U   321                                                      
REMARK 465     GLU U   322                                                      
REMARK 465     LYS U   323                                                      
REMARK 465     LYS U   324                                                      
REMARK 465     MET V     1                                                      
REMARK 465     ASP V     2                                                      
REMARK 465     ARG V     3                                                      
REMARK 465     LEU V     4                                                      
REMARK 465     LEU V     5                                                      
REMARK 465     ARG V     6                                                      
REMARK 465     LEU V     7                                                      
REMARK 465     GLY V     8                                                      
REMARK 465     GLY V     9                                                      
REMARK 465     GLY V    10                                                      
REMARK 465     MET V    11                                                      
REMARK 465     PRO V    12                                                      
REMARK 465     GLY V    13                                                      
REMARK 465     LEU V    14                                                      
REMARK 465     GLY V    15                                                      
REMARK 465     GLN V    16                                                      
REMARK 465     GLY V    17                                                      
REMARK 465     PRO V    18                                                      
REMARK 465     PRO V    19                                                      
REMARK 465     THR V    20                                                      
REMARK 465     ASP V    21                                                      
REMARK 465     ALA V    22                                                      
REMARK 465     PRO V    23                                                      
REMARK 465     ALA V    24                                                      
REMARK 465     VAL V    25                                                      
REMARK 465     ASP V    26                                                      
REMARK 465     THR V    27                                                      
REMARK 465     GLY V   171                                                      
REMARK 465     HIS V   172                                                      
REMARK 465     GLU V   173                                                      
REMARK 465     PRO V   174                                                      
REMARK 465     ARG V   175                                                      
REMARK 465     GLN V   176                                                      
REMARK 465     THR V   177                                                      
REMARK 465     THR V   178                                                      
REMARK 465     SER V   179                                                      
REMARK 465     ASN V   180                                                      
REMARK 465     LEU V   181                                                      
REMARK 465     GLY V   182                                                      
REMARK 465     HIS V   183                                                      
REMARK 465     SER V   224                                                      
REMARK 465     TRP V   225                                                      
REMARK 465     MET V   226                                                      
REMARK 465     GLU V   227                                                      
REMARK 465     GLY V   228                                                      
REMARK 465     LEU V   229                                                      
REMARK 465     THR V   230                                                      
REMARK 465     LEU V   231                                                      
REMARK 465     GLN V   232                                                      
REMARK 465     ASP V   233                                                      
REMARK 465     MET V   303                                                      
REMARK 465     LEU V   304                                                      
REMARK 465     ASP V   305                                                      
REMARK 465     THR V   306                                                      
REMARK 465     VAL V   307                                                      
REMARK 465     VAL V   308                                                      
REMARK 465     PHE V   309                                                      
REMARK 465     LYS V   310                                                      
REMARK 465     SER W   186                                                      
REMARK 465     PRO W   187                                                      
REMARK 465     ILE W   188                                                      
REMARK 465     LEU W   189                                                      
REMARK 465     ALA W   190                                                      
REMARK 465     GLY W   191                                                      
REMARK 465     GLU W   192                                                      
REMARK 465     GLY W   193                                                      
REMARK 465     GLY W   194                                                      
REMARK 465     ALA W   195                                                      
REMARK 465     MET W   196                                                      
REMARK 465     LEU W   197                                                      
REMARK 465     GLY W   198                                                      
REMARK 465     LEU W   199                                                      
REMARK 465     GLY W   200                                                      
REMARK 465     ALA W   201                                                      
REMARK 465     SER W   202                                                      
REMARK 465     ASP W   203                                                      
REMARK 465     PHE W   204                                                      
REMARK 465     GLU W   205                                                      
REMARK 465     PHE W   206                                                      
REMARK 465     GLY W   207                                                      
REMARK 465     VAL W   208                                                      
REMARK 465     ASP W   209                                                      
REMARK 465     PRO W   210                                                      
REMARK 465     SER W   211                                                      
REMARK 465     ALA W   212                                                      
REMARK 465     ASP W   213                                                      
REMARK 465     PRO W   214                                                      
REMARK 465     GLU W   215                                                      
REMARK 465     LEU W   216                                                      
REMARK 465     ALA W   217                                                      
REMARK 465     LEU W   218                                                      
REMARK 465     ALA W   219                                                      
REMARK 465     LEU W   220                                                      
REMARK 465     ARG W   221                                                      
REMARK 465     VAL W   222                                                      
REMARK 465     SER W   223                                                      
REMARK 465     MET W   224                                                      
REMARK 465     GLU W   225                                                      
REMARK 465     GLU W   226                                                      
REMARK 465     GLN W   227                                                      
REMARK 465     ARG W   228                                                      
REMARK 465     GLN W   229                                                      
REMARK 465     ARG W   230                                                      
REMARK 465     GLN W   231                                                      
REMARK 465     GLU W   232                                                      
REMARK 465     GLU W   233                                                      
REMARK 465     GLU W   234                                                      
REMARK 465     ALA W   235                                                      
REMARK 465     ARG W   236                                                      
REMARK 465     ARG W   237                                                      
REMARK 465     ALA W   238                                                      
REMARK 465     ALA W   239                                                      
REMARK 465     ALA W   240                                                      
REMARK 465     ALA W   241                                                      
REMARK 465     SER W   242                                                      
REMARK 465     ALA W   243                                                      
REMARK 465     ALA W   244                                                      
REMARK 465     GLU W   245                                                      
REMARK 465     ALA W   246                                                      
REMARK 465     GLY W   247                                                      
REMARK 465     ILE W   248                                                      
REMARK 465     ALA W   249                                                      
REMARK 465     THR W   250                                                      
REMARK 465     THR W   251                                                      
REMARK 465     GLY W   252                                                      
REMARK 465     THR W   253                                                      
REMARK 465     GLU W   254                                                      
REMARK 465     ASP W   255                                                      
REMARK 465     SER W   256                                                      
REMARK 465     ASP W   257                                                      
REMARK 465     ASP W   258                                                      
REMARK 465     ALA W   259                                                      
REMARK 465     LEU W   260                                                      
REMARK 465     LEU W   261                                                      
REMARK 465     LYS W   262                                                      
REMARK 465     MET W   263                                                      
REMARK 465     THR W   264                                                      
REMARK 465     ILE W   265                                                      
REMARK 465     SER W   266                                                      
REMARK 465     GLN W   267                                                      
REMARK 465     GLN W   268                                                      
REMARK 465     GLU W   269                                                      
REMARK 465     PHE W   270                                                      
REMARK 465     GLY W   271                                                      
REMARK 465     ARG W   272                                                      
REMARK 465     THR W   273                                                      
REMARK 465     GLY W   274                                                      
REMARK 465     LEU W   275                                                      
REMARK 465     PRO W   276                                                      
REMARK 465     ASP W   277                                                      
REMARK 465     LEU W   278                                                      
REMARK 465     SER W   279                                                      
REMARK 465     SER W   280                                                      
REMARK 465     MET W   281                                                      
REMARK 465     THR W   282                                                      
REMARK 465     GLU W   283                                                      
REMARK 465     GLU W   284                                                      
REMARK 465     GLU W   285                                                      
REMARK 465     GLN W   286                                                      
REMARK 465     ILE W   287                                                      
REMARK 465     ALA W   288                                                      
REMARK 465     TYR W   289                                                      
REMARK 465     ALA W   290                                                      
REMARK 465     MET W   291                                                      
REMARK 465     GLN W   292                                                      
REMARK 465     MET W   293                                                      
REMARK 465     SER W   294                                                      
REMARK 465     LEU W   295                                                      
REMARK 465     GLN W   296                                                      
REMARK 465     GLY W   297                                                      
REMARK 465     ALA W   298                                                      
REMARK 465     GLU W   299                                                      
REMARK 465     PHE W   300                                                      
REMARK 465     GLY W   301                                                      
REMARK 465     GLN W   302                                                      
REMARK 465     ALA W   303                                                      
REMARK 465     GLU W   304                                                      
REMARK 465     SER W   305                                                      
REMARK 465     ALA W   306                                                      
REMARK 465     ASP W   307                                                      
REMARK 465     ILE W   308                                                      
REMARK 465     ASP W   309                                                      
REMARK 465     ALA W   310                                                      
REMARK 465     SER W   311                                                      
REMARK 465     SER W   312                                                      
REMARK 465     ALA W   313                                                      
REMARK 465     MET W   314                                                      
REMARK 465     ASP W   315                                                      
REMARK 465     THR W   316                                                      
REMARK 465     SER W   317                                                      
REMARK 465     GLU W   318                                                      
REMARK 465     PRO W   319                                                      
REMARK 465     ALA W   320                                                      
REMARK 465     LYS W   321                                                      
REMARK 465     GLU W   322                                                      
REMARK 465     GLU W   323                                                      
REMARK 465     ASP W   324                                                      
REMARK 465     ASP W   325                                                      
REMARK 465     TYR W   326                                                      
REMARK 465     ASP W   327                                                      
REMARK 465     VAL W   328                                                      
REMARK 465     MET W   329                                                      
REMARK 465     GLN W   330                                                      
REMARK 465     ASP W   331                                                      
REMARK 465     PRO W   332                                                      
REMARK 465     GLU W   333                                                      
REMARK 465     PHE W   334                                                      
REMARK 465     LEU W   335                                                      
REMARK 465     GLN W   336                                                      
REMARK 465     SER W   337                                                      
REMARK 465     VAL W   338                                                      
REMARK 465     LEU W   339                                                      
REMARK 465     GLU W   340                                                      
REMARK 465     ASN W   341                                                      
REMARK 465     LEU W   342                                                      
REMARK 465     PRO W   343                                                      
REMARK 465     GLY W   344                                                      
REMARK 465     VAL W   345                                                      
REMARK 465     ASP W   346                                                      
REMARK 465     PRO W   347                                                      
REMARK 465     ASN W   348                                                      
REMARK 465     ASN W   349                                                      
REMARK 465     GLU W   350                                                      
REMARK 465     ALA W   351                                                      
REMARK 465     ILE W   352                                                      
REMARK 465     ARG W   353                                                      
REMARK 465     ASN W   354                                                      
REMARK 465     ALA W   355                                                      
REMARK 465     MET W   356                                                      
REMARK 465     GLY W   357                                                      
REMARK 465     SER W   358                                                      
REMARK 465     LEU W   359                                                      
REMARK 465     ALA W   360                                                      
REMARK 465     SER W   361                                                      
REMARK 465     GLN W   362                                                      
REMARK 465     ALA W   363                                                      
REMARK 465     THR W   364                                                      
REMARK 465     LYS W   365                                                      
REMARK 465     ASP W   366                                                      
REMARK 465     GLY W   367                                                      
REMARK 465     LYS W   368                                                      
REMARK 465     LYS W   369                                                      
REMARK 465     ASP W   370                                                      
REMARK 465     LYS W   371                                                      
REMARK 465     LYS W   372                                                      
REMARK 465     GLU W   373                                                      
REMARK 465     GLU W   374                                                      
REMARK 465     ASP W   375                                                      
REMARK 465     LYS W   376                                                      
REMARK 465     LYS W   377                                                      
REMARK 465     MET Y     1                                                      
REMARK 465     SER Y     2                                                      
REMARK 465     GLU Y     3                                                      
REMARK 465     LYS Y     4                                                      
REMARK 465     LYS Y     5                                                      
REMARK 465     GLN Y     6                                                      
REMARK 465     PRO Y     7                                                      
REMARK 465     VAL Y     8                                                      
REMARK 465     ASP Y     9                                                      
REMARK 465     LEU Y    10                                                      
REMARK 465     GLY Y    11                                                      
REMARK 465     LEU Y    12                                                      
REMARK 465     LEU Y    13                                                      
REMARK 465     GLU Y    14                                                      
REMARK 465     GLU Y    15                                                      
REMARK 465     ASP Y    16                                                      
REMARK 465     ASP Y    17                                                      
REMARK 465     GLU Y    18                                                      
REMARK 465     PHE Y    19                                                      
REMARK 465     GLU Y    20                                                      
REMARK 465     GLU Y    21                                                      
REMARK 465     PHE Y    22                                                      
REMARK 465     PRO Y    23                                                      
REMARK 465     ALA Y    24                                                      
REMARK 465     GLU Y    25                                                      
REMARK 465     ASP Y    26                                                      
REMARK 465     TRP Y    27                                                      
REMARK 465     ALA Y    28                                                      
REMARK 465     GLY Y    29                                                      
REMARK 465     LEU Y    30                                                      
REMARK 465     ASP Y    31                                                      
REMARK 465     GLU Y    32                                                      
REMARK 465     ASP Y    33                                                      
REMARK 465     GLU Y    34                                                      
REMARK 465     ASP Y    35                                                      
REMARK 465     ALA Y    36                                                      
REMARK 465     HIS Y    37                                                      
REMARK 465     VAL Y    38                                                      
REMARK 465     TRP Y    39                                                      
REMARK 465     GLU Y    40                                                      
REMARK 465     ASP Y    41                                                      
REMARK 465     ASN Y    42                                                      
REMARK 465     TRP Y    43                                                      
REMARK 465     ASP Y    44                                                      
REMARK 465     ASP Y    45                                                      
REMARK 465     ASP Y    46                                                      
REMARK 465     ASN Y    47                                                      
REMARK 465     VAL Y    48                                                      
REMARK 465     GLU Y    49                                                      
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: COVALENT BOND LENGTHS                                      
REMARK 500                                                                      
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES              
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE               
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                 
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT: (10X,I3,1X,2(A3,1X,A1,I4,A1,1X,A4,3X),1X,F6.3)               
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999                        
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996                     
REMARK 500                                                                      
REMARK 500  M RES CSSEQI ATM1   RES CSSEQI ATM2   DEVIATION                     
REMARK 500    ARG Z  79   NE    ARG Z  79   CZ      0.083                       
REMARK 500    GLY Z 116   CA    GLY Z 116   C      -0.108                       
REMARK 500    ARG Z 143   NE    ARG Z 143   CZ      0.082                       
REMARK 500    TRP Z 170   NE1   TRP Z 170   CE2     0.082                       
REMARK 500    TYR Z 194   CG    TYR Z 194   CD2     0.086                       
REMARK 500    TYR Z 232   CG    TYR Z 232   CD2     0.091                       
REMARK 500    ARG Z 335   NE    ARG Z 335   CZ      0.096                       
REMARK 500    TRP Z 398   CE3   TRP Z 398   CZ3     0.106                       
REMARK 500    ARG Z 456   CD    ARG Z 456   NE      0.107                       
REMARK 500    ARG Z 478   NE    ARG Z 478   CZ      0.079                       
REMARK 500    TYR Z 554   CZ    TYR Z 554   CE2     0.078                       
REMARK 500    SER Z 589   CA    SER Z 589   CB      0.113                       
REMARK 500    ARG Z 680   CD    ARG Z 680   NE      0.113                       
REMARK 500    ARG Z 687   CZ    ARG Z 687   NH2     0.095                       
REMARK 500    GLU Z 720   CG    GLU Z 720   CD      0.105                       
REMARK 500    TYR Z 723   CZ    TYR Z 723   CE2     0.079                       
REMARK 500    TYR Z 751   CG    TYR Z 751   CD2     0.082                       
REMARK 500    ARG Z 763   CD    ARG Z 763   NE      0.118                       
REMARK 500    TYR Z 819   CG    TYR Z 819   CD1     0.093                       
REMARK 500    ARG 1  74   CZ    ARG 1  74   NH2     0.086                       
REMARK 500    ARG 1 123   CZ    ARG 1 123   NH2     0.084                       
REMARK 500    ARG 1 156   CZ    ARG 1 156   NH2     0.079                       
REMARK 500    PHE 1 231   CZ    PHE 1 231   CE2     0.120                       
REMARK 500    THR 2  44   N     THR 2  44   CA      0.123                       
REMARK 500    PHE 2  79   CG    PHE 2  79   CD2     0.093                       
REMARK 500    SER 2 110   CA    SER 2 110   CB      0.117                       
REMARK 500    ARG 2 132   CZ    ARG 2 132   NH2     0.105                       
REMARK 500    ARG 2 186   CZ    ARG 2 186   NH2     0.093                       
REMARK 500    GLU 2 191   CG    GLU 2 191   CD      0.127                       
REMARK 500    TYR 2 232   CZ    TYR 2 232   CE2     0.090                       
REMARK 500    ARG 3  26   NE    ARG 3  26   CZ      0.088                       
REMARK 500    PRO 3  44   CD    PRO 3  44   N      -0.087                       
REMARK 500    SER 3  89   CA    SER 3  89   CB      0.102                       
REMARK 500    HIS 3 162   CG    HIS 3 162   CD2     0.058                       
REMARK 500    ARG 3 177   CZ    ARG 3 177   NH2     0.097                       
REMARK 500    GLU 4  58   CD    GLU 4  58   OE1     0.073                       
REMARK 500    GLY 4 187   CA    GLY 4 187   C      -0.107                       
REMARK 500    HIS 5  69   CG    HIS 5  69   CD2     0.056                       
REMARK 500    ARG 5 116   CZ    ARG 5 116   NH2     0.086                       
REMARK 500    ARG 5 128   CZ    ARG 5 128   NH1     0.079                       
REMARK 500    TYR 5 195   CE1   TYR 5 195   CZ      0.111                       
REMARK 500    ARG 5 216   NE    ARG 5 216   CZ      0.079                       
REMARK 500    ARG 5 216   CZ    ARG 5 216   NH2     0.085                       
REMARK 500    TYR 5 224   CZ    TYR 5 224   OH      0.102                       
REMARK 500    ARG 5 239   CZ    ARG 5 239   NH2     0.087                       
REMARK 500    SER 6  31   CA    SER 6  31   CB      0.119                       
REMARK 500    TYR 6  33   CZ    TYR 6  33   OH      0.111                       
REMARK 500    TYR 6 135   CZ    TYR 6 135   OH      0.103                       
REMARK 500    SER 6 162   CA    SER 6 162   CB      0.095                       
REMARK 500    ARG 6 222   CD    ARG 6 222   NE      0.110                       
REMARK 500                                                                      
REMARK 500 THIS ENTRY HAS     231 BOND DEVIATIONS.                              
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES                                       
REMARK 500                                                                      
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES              
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE               
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                 
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)              
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999                        
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996                     
REMARK 500                                                                      
REMARK 500  M RES CSSEQI ATM1   ATM2   ATM3                                     
REMARK 500    ARG Z  62   NE  -  CZ  -  NH1 ANGL. DEV. =  -4.4 DEGREES          
REMARK 500    ARG Z  62   NE  -  CZ  -  NH2 ANGL. DEV. =   4.1 DEGREES          
REMARK 500    TYR Z  71   CB  -  CG  -  CD2 ANGL. DEV. =  -7.5 DEGREES          
REMARK 500    TYR Z  71   CB  -  CG  -  CD1 ANGL. DEV. =   4.8 DEGREES          
REMARK 500    ARG Z  72   NE  -  CZ  -  NH1 ANGL. DEV. =   6.8 DEGREES          
REMARK 500    ARG Z 100   NE  -  CZ  -  NH1 ANGL. DEV. =   5.1 DEGREES          
REMARK 500    TYR Z 103   CB  -  CG  -  CD2 ANGL. DEV. =   5.3 DEGREES          
REMARK 500    TYR Z 103   CB  -  CG  -  CD1 ANGL. DEV. =  -6.6 DEGREES          
REMARK 500    GLU Z 136   OE1 -  CD  -  OE2 ANGL. DEV. =   8.2 DEGREES          
REMARK 500    ARG Z 143   NE  -  CZ  -  NH2 ANGL. DEV. =   3.4 DEGREES          
REMARK 500    ARG Z 181   NE  -  CZ  -  NH1 ANGL. DEV. =   4.1 DEGREES          
REMARK 500    ARG Z 181   NE  -  CZ  -  NH2 ANGL. DEV. =  -3.9 DEGREES          
REMARK 500    TYR Z 194   CB  -  CG  -  CD2 ANGL. DEV. =   3.7 DEGREES          
REMARK 500    LEU Z 217   CB  -  CG  -  CD2 ANGL. DEV. =  14.0 DEGREES          
REMARK 500    ALA Z 227   N   -  CA  -  CB  ANGL. DEV. =  10.0 DEGREES          
REMARK 500    TYR Z 239   CB  -  CG  -  CD1 ANGL. DEV. =   3.6 DEGREES          
REMARK 500    TYR Z 239   CZ  -  CE2 -  CD2 ANGL. DEV. =   5.5 DEGREES          
REMARK 500    ARG Z 250   NE  -  CZ  -  NH2 ANGL. DEV. =  -4.5 DEGREES          
REMARK 500    MET Z 275   CA  -  CB  -  CG  ANGL. DEV. =  10.8 DEGREES          
REMARK 500    ASP Z 310   CB  -  CG  -  OD1 ANGL. DEV. =  -6.0 DEGREES          
REMARK 500    PHE Z 330   CB  -  CG  -  CD1 ANGL. DEV. =   5.8 DEGREES          
REMARK 500    ASP Z 346   CB  -  CG  -  OD1 ANGL. DEV. =  -6.7 DEGREES          
REMARK 500    TYR Z 349   CB  -  CG  -  CD2 ANGL. DEV. =  -7.7 DEGREES          
REMARK 500    TYR Z 349   CB  -  CG  -  CD1 ANGL. DEV. =   4.0 DEGREES          
REMARK 500    PHE Z 380   CB  -  CG  -  CD1 ANGL. DEV. =   7.4 DEGREES          
REMARK 500    MET Z 407   CG  -  SD  -  CE  ANGL. DEV. = -15.8 DEGREES          
REMARK 500    MET Z 416   CG  -  SD  -  CE  ANGL. DEV. = -15.0 DEGREES          
REMARK 500    TYR Z 432   CB  -  CG  -  CD1 ANGL. DEV. =  -4.7 DEGREES          
REMARK 500    TYR Z 434   CB  -  CG  -  CD2 ANGL. DEV. =  -5.3 DEGREES          
REMARK 500    TYR Z 439   CB  -  CG  -  CD2 ANGL. DEV. =  -6.5 DEGREES          
REMARK 500    TYR Z 469   CB  -  CG  -  CD2 ANGL. DEV. =  -9.7 DEGREES          
REMARK 500    TYR Z 469   CB  -  CG  -  CD1 ANGL. DEV. =   6.8 DEGREES          
REMARK 500    TYR Z 489   CB  -  CG  -  CD2 ANGL. DEV. =  -4.3 DEGREES          
REMARK 500    TYR Z 489   CG  -  CD2 -  CE2 ANGL. DEV. =  -6.2 DEGREES          
REMARK 500    TYR Z 489   CZ  -  CE2 -  CD2 ANGL. DEV. =   5.7 DEGREES          
REMARK 500    ALA Z 519   CB  -  CA  -  C   ANGL. DEV. =  -9.2 DEGREES          
REMARK 500    VAL Z 527   CA  -  CB  -  CG2 ANGL. DEV. = -12.2 DEGREES          
REMARK 500    TYR Z 554   CB  -  CG  -  CD2 ANGL. DEV. =   3.8 DEGREES          
REMARK 500    ALA Z 591   N   -  CA  -  CB  ANGL. DEV. =   8.8 DEGREES          
REMARK 500    TYR Z 600   CB  -  CG  -  CD2 ANGL. DEV. =  -3.6 DEGREES          
REMARK 500    TYR Z 600   CB  -  CG  -  CD1 ANGL. DEV. =   4.7 DEGREES          
REMARK 500    HIS Z 614   CA  -  CB  -  CG  ANGL. DEV. =  12.0 DEGREES          
REMARK 500    CYS Z 616   N   -  CA  -  CB  ANGL. DEV. =   9.9 DEGREES          
REMARK 500    ARG Z 673   NE  -  CZ  -  NH1 ANGL. DEV. =   4.3 DEGREES          
REMARK 500    THR Z 674   CA  -  CB  -  CG2 ANGL. DEV. =  -8.8 DEGREES          
REMARK 500    LEU Z 678   CB  -  CG  -  CD2 ANGL. DEV. =  12.3 DEGREES          
REMARK 500    TYR Z 681   CB  -  CA  -  C   ANGL. DEV. = -13.3 DEGREES          
REMARK 500    ARG Z 688   NE  -  CZ  -  NH2 ANGL. DEV. =   3.2 DEGREES          
REMARK 500    ALA Z 695   N   -  CA  -  CB  ANGL. DEV. =   9.5 DEGREES          
REMARK 500    ARG Z 703   NE  -  CZ  -  NH1 ANGL. DEV. =   4.4 DEGREES          
REMARK 500                                                                      
REMARK 500 THIS ENTRY HAS    1012 ANGLE DEVIATIONS.                             
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: TORSION ANGLES                                             
REMARK 500                                                                      
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:            
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)                    
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-           
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400            
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        PSI       PHI                                   
REMARK 500    LYS Z  94      121.17     66.85                                   
REMARK 500    SER Z 147        9.10   -166.47                                   
REMARK 500    SER Z 153     -174.70     53.42                                   
REMARK 500    TRP Z 154       -8.01   -156.10                                   
REMARK 500    HIS Z 156     -166.57   -123.76                                   
REMARK 500    ASP Z 174       40.93     85.74                                   
REMARK 500    GLU Z 177     -158.06   -101.31                                   
REMARK 500    ASP Z 222       14.11   -143.28                                   
REMARK 500    ASN Z 224      167.02     79.72                                   
REMARK 500    SER Z 260       57.44     89.18                                   
REMARK 500    ARG Z 261       68.46   -116.11                                   
REMARK 500    MET Z 271      121.97     72.96                                   
REMARK 500    LEU Z 272       42.11     76.39                                   
REMARK 500    LYS Z 286       32.56   -140.09                                   
REMARK 500    HIS Z 301       89.99   -162.46                                   
REMARK 500    VAL Z 303        2.29   -168.61                                   
REMARK 500    PHE Z 304      -11.21   -147.76                                   
REMARK 500    GLU Z 306     -147.44     27.16                                   
REMARK 500    ASP Z 316      110.67     68.52                                   
REMARK 500    LEU Z 317       -7.85   -147.85                                   
REMARK 500    LEU Z 331       33.50     82.38                                   
REMARK 500    ARG Z 357     -176.67     62.56                                   
REMARK 500    PHE Z 358      116.57   -179.97                                   
REMARK 500    VAL Z 365      174.45     45.99                                   
REMARK 500    SER Z 367      143.85     91.29                                   
REMARK 500    PHE Z 385      145.77     76.98                                   
REMARK 500    ASP Z 394       58.09    -94.14                                   
REMARK 500    ASP Z 404     -143.07     63.43                                   
REMARK 500    LEU Z 419      126.44    -23.20                                   
REMARK 500    TRP Z 420      -16.79     86.05                                   
REMARK 500    ASP Z 423      -70.88    -71.20                                   
REMARK 500    SER Z 435     -152.72     57.92                                   
REMARK 500    SER Z 436     -156.44     63.84                                   
REMARK 500    CYS Z 459        3.86   -155.91                                   
REMARK 500    PRO Z 461      109.70    -56.66                                   
REMARK 500    HIS Z 472     -152.96    -81.49                                   
REMARK 500    ALA Z 490       63.70     37.51                                   
REMARK 500    SER Z 510      -12.00   -158.36                                   
REMARK 500    SER Z 511       14.50   -161.71                                   
REMARK 500    GLU Z 513        0.95   -167.33                                   
REMARK 500    GLU Z 547       12.04   -145.39                                   
REMARK 500    GLU Z 549      -15.65   -161.86                                   
REMARK 500    ALA Z 601       48.28     76.70                                   
REMARK 500    ALA Z 717      145.72    -35.83                                   
REMARK 500    ASP Z 718      129.77     86.76                                   
REMARK 500    ALA Z 739     -109.38   -113.22                                   
REMARK 500    ALA Z 753       36.07   -170.80                                   
REMARK 500    CYS Z 779       98.17    175.24                                   
REMARK 500    SER Z 802       84.69     63.31                                   
REMARK 500    ASN Z 808     -148.01     48.73                                   
REMARK 500                                                                      
REMARK 500 THIS ENTRY HAS     651 RAMACHANDRAN OUTLIERS.                        
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: NON-CIS, NON-TRANS                                         
REMARK 500                                                                      
REMARK 500 THE FOLLOWING PEPTIDE BONDS DEVIATE SIGNIFICANTLY FROM BOTH          
REMARK 500 CIS AND TRANS CONFORMATION.  CIS BONDS, IF ANY, ARE LISTED           
REMARK 500 ON CISPEP RECORDS.  TRANS IS DEFINED AS 180 +/- 30 AND               
REMARK 500 CIS IS DEFINED AS 0 +/- 30 DEGREES.                                  
REMARK 500                                 MODEL     OMEGA                      
REMARK 500 GLU Z  341     PRO Z  342                 -145.57                    
REMARK 500 PRO H   75     ALA H   76                 -128.78                    
REMARK 500 GLU H  107     ASP H  108                  148.93                    
REMARK 500 ALA H  283     ARG H  284                 -123.31                    
REMARK 500 LYS K  409     ASP K  410                 -148.40                    
REMARK 500 CYS M  121     ALA M  122                  149.23                    
REMARK 500 GLN M  321     PRO M  322                 -149.23                    
REMARK 500 SER M  376     PRO M  377                 -149.95                    
REMARK 500 LYS N  210     PRO N  211                  136.56                    
REMARK 500 GLU O  208     GLY O  209                  140.52                    
REMARK 500 ASP O  342     LEU O  343                 -134.39                    
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: PLANAR GROUPS                                              
REMARK 500                                                                      
REMARK 500 PLANAR GROUPS IN THE FOLLOWING RESIDUES HAVE A TOTAL                 
REMARK 500 RMS DISTANCE OF ALL ATOMS FROM THE BEST-FIT PLANE                    
REMARK 500 BY MORE THAN AN EXPECTED VALUE OF 6*RMSD, WITH AN                    
REMARK 500 RMSD 0.02 ANGSTROMS, OR AT LEAST ONE ATOM HAS                        
REMARK 500 AN RMSD GREATER THAN THIS VALUE                                      
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        RMS     TYPE                                    
REMARK 500    ARG Z  62         0.09    SIDE CHAIN                              
REMARK 500    ARG Z  79         0.10    SIDE CHAIN                              
REMARK 500    TYR Z 110         0.09    SIDE CHAIN                              
REMARK 500    ARG Z 120         0.08    SIDE CHAIN                              
REMARK 500    ARG Z 143         0.09    SIDE CHAIN                              
REMARK 500    TYR Z 239         0.09    SIDE CHAIN                              
REMARK 500    TYR Z 434         0.12    SIDE CHAIN                              
REMARK 500    TYR Z 439         0.09    SIDE CHAIN                              
REMARK 500    TYR Z 469         0.07    SIDE CHAIN                              
REMARK 500    PHE Z 587         0.09    SIDE CHAIN                              
REMARK 500    PHE Z 713         0.09    SIDE CHAIN                              
REMARK 500    ARG Z 740         0.09    SIDE CHAIN                              
REMARK 500    ARG Z 746         0.12    SIDE CHAIN                              
REMARK 500    TYR Z 751         0.07    SIDE CHAIN                              
REMARK 500    ARG Z 763         0.08    SIDE CHAIN                              
REMARK 500    TYR Z 781         0.08    SIDE CHAIN                              
REMARK 500    TYR Z 816         0.07    SIDE CHAIN                              
REMARK 500    ARG Z 828         0.09    SIDE CHAIN                              
REMARK 500    TYR 1  59         0.07    SIDE CHAIN                              
REMARK 500    TYR 1 124         0.08    SIDE CHAIN                              
REMARK 500    ARG 1 178         0.10    SIDE CHAIN                              
REMARK 500    ARG 2 115         0.10    SIDE CHAIN                              
REMARK 500    TYR 2 157         0.11    SIDE CHAIN                              
REMARK 500    TYR 2 167         0.17    SIDE CHAIN                              
REMARK 500    ARG 2 186         0.10    SIDE CHAIN                              
REMARK 500    PHE 2 207         0.09    SIDE CHAIN                              
REMARK 500    TYR 3   6         0.09    SIDE CHAIN                              
REMARK 500    ARG 3  80         0.07    SIDE CHAIN                              
REMARK 500    PHE 3 100         0.09    SIDE CHAIN                              
REMARK 500    TYR 4  12         0.09    SIDE CHAIN                              
REMARK 500    ARG 4  85         0.14    SIDE CHAIN                              
REMARK 500    ARG 4  93         0.09    SIDE CHAIN                              
REMARK 500    TYR 4  98         0.08    SIDE CHAIN                              
REMARK 500    TYR 4 117         0.11    SIDE CHAIN                              
REMARK 500    PHE 4 129         0.08    SIDE CHAIN                              
REMARK 500    ARG 4 145         0.08    SIDE CHAIN                              
REMARK 500    TYR 5  99         0.10    SIDE CHAIN                              
REMARK 500    TYR 5 147         0.09    SIDE CHAIN                              
REMARK 500    ARG 5 179         0.07    SIDE CHAIN                              
REMARK 500    TYR 5 204         0.09    SIDE CHAIN                              
REMARK 500    GLU 5 209         0.08    SIDE CHAIN                              
REMARK 500    ARG 5 245         0.12    SIDE CHAIN                              
REMARK 500    PHE 6  30         0.15    SIDE CHAIN                              
REMARK 500    PHE 6  61         0.10    SIDE CHAIN                              
REMARK 500    TYR 6  72         0.08    SIDE CHAIN                              
REMARK 500    TYR 6 125         0.14    SIDE CHAIN                              
REMARK 500    TYR 6 133         0.12    SIDE CHAIN                              
REMARK 500    PHE 6 152         0.08    SIDE CHAIN                              
REMARK 500    ARG 6 198         0.11    SIDE CHAIN                              
REMARK 500    ARG 6 201         0.08    SIDE CHAIN                              
REMARK 500                                                                      
REMARK 500 THIS ENTRY HAS     254 PLANE DEVIATIONS.                             
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: MAIN CHAIN PLANARITY                                       
REMARK 500                                                                      
REMARK 500 THE FOLLOWING RESIDUES HAVE A PSEUDO PLANARITY                       
REMARK 500 TORSION ANGLE, C(I) - CA(I) - N(I+1) - O(I), GREATER                 
REMARK 500 10.0 DEGREES. (M=MODEL NUMBER; RES=RESIDUE NAME;                     
REMARK 500 C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;                            
REMARK 500 I=INSERTION CODE).                                                   
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        ANGLE                                           
REMARK 500    ASP J 104         10.96                                           
REMARK 500    ALA O 110        -10.92                                           
REMARK 500    TRP U  68         10.50                                           
REMARK 500    HIS V 237        -11.09                                           
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 900                                                                      
REMARK 900 RELATED ENTRIES                                                      
REMARK 900 RELATED ID: EMD-4089   RELATED DB: EMDB                              
REMARK 900 THE HUMAN 26S PROTEASOME AT 6.8 ANG.                                 
DBREF  5LN3 Z    1   908  UNP    Q13200   PSMD2_HUMAN      1    908             
DBREF  5LN3 1    1   239  UNP    P28072   PSB6_HUMAN       1    239             
DBREF  5LN3 2    1   277  UNP    Q99436   PSB7_HUMAN       1    277             
DBREF  5LN3 3    1   205  UNP    P49720   PSB3_HUMAN       1    205             
DBREF  5LN3 4    1   201  UNP    P49721   PSB2_HUMAN       1    201             
DBREF  5LN3 5    1   263  UNP    P28074   PSB5_HUMAN       1    263             
DBREF  5LN3 6    1   241  UNP    P20618   PSB1_HUMAN       1    241             
DBREF  5LN3 7    1   264  UNP    P28070   PSB4_HUMAN       1    264             
DBREF  5LN3 A    1   246  UNP    P60900   PSA6_HUMAN       1    246             
DBREF  5LN3 B    1   234  UNP    P25787   PSA2_HUMAN       1    234             
DBREF  5LN3 C    1   261  UNP    P25789   PSA4_HUMAN       1    261             
DBREF  5LN3 D    1   248  UNP    O14818   PSA7_HUMAN       1    248             
DBREF  5LN3 E    1   241  UNP    P28066   PSA5_HUMAN       1    241             
DBREF  5LN3 F    1   263  UNP    P25786   PSA1_HUMAN       1    263             
DBREF  5LN3 G    1   255  UNP    P25788   PSA3_HUMAN       1    255             
DBREF  5LN3 H    1   433  UNP    P35998   PRS7_HUMAN       1    433             
DBREF  5LN3 I    1   440  UNP    P62191   PRS4_HUMAN       1    440             
DBREF  5LN3 J    1   406  UNP    P62195   PRS8_HUMAN       1    406             
DBREF  5LN3 K    1   418  UNP    P43686   PRS6B_HUMAN      1    418             
DBREF  5LN3 L    1   389  UNP    P62333   PRS10_HUMAN      1    389             
DBREF  5LN3 M    1   439  UNP    P17980   PRS6A_HUMAN      1    439             
DBREF  5LN3 N    1   953  UNP    Q99460   PSMD1_HUMAN      1    953             
DBREF  5LN3 O    1   376  UNP    Q9UNM6   PSD13_HUMAN      1    376             
DBREF  5LN3 P    1   456  UNP    O00232   PSD12_HUMAN      1    456             
DBREF  5LN3 Q    1   422  UNP    O00231   PSD11_HUMAN      1    422             
DBREF  5LN3 R    1   389  UNP    Q15008   PSMD6_HUMAN      1    389             
DBREF  5LN3 S    1   534  UNP    O43242   PSMD3_HUMAN      1    534             
DBREF  5LN3 T    1   350  UNP    P48556   PSMD8_HUMAN      1    350             
DBREF  5LN3 U    1   324  UNP    P51665   PSMD7_HUMAN      1    324             
DBREF  5LN3 V    1   310  UNP    O00487   PSDE_HUMAN       1    310             
DBREF  5LN3 W    1   377  UNP    P55036   PSMD4_HUMAN      1    377             
DBREF  5LN3 Y    1    70  UNP    P60896   DSS1_HUMAN       1     70             
SEQRES   1 Z  908  MET GLU GLU GLY GLY ARG ASP LYS ALA PRO VAL GLN PRO          
SEQRES   2 Z  908  GLN GLN SER PRO ALA ALA ALA PRO GLY GLY THR ASP GLU          
SEQRES   3 Z  908  LYS PRO SER GLY LYS GLU ARG ARG ASP ALA GLY ASP LYS          
SEQRES   4 Z  908  ASP LYS GLU GLN GLU LEU SER GLU GLU ASP LYS GLN LEU          
SEQRES   5 Z  908  GLN ASP GLU LEU GLU MET LEU VAL GLU ARG LEU GLY GLU          
SEQRES   6 Z  908  LYS ASP THR SER LEU TYR ARG PRO ALA LEU GLU GLU LEU          
SEQRES   7 Z  908  ARG ARG GLN ILE ARG SER SER THR THR SER MET THR SER          
SEQRES   8 Z  908  VAL PRO LYS PRO LEU LYS PHE LEU ARG PRO HIS TYR GLY          
SEQRES   9 Z  908  LYS LEU LYS GLU ILE TYR GLU ASN MET ALA PRO GLY GLU          
SEQRES  10 Z  908  ASN LYS ARG PHE ALA ALA ASP ILE ILE SER VAL LEU ALA          
SEQRES  11 Z  908  MET THR MET SER GLY GLU ARG GLU CYS LEU LYS TYR ARG          
SEQRES  12 Z  908  LEU VAL GLY SER GLN GLU GLU LEU ALA SER TRP GLY HIS          
SEQRES  13 Z  908  GLU TYR VAL ARG HIS LEU ALA GLY GLU VAL ALA LYS GLU          
SEQRES  14 Z  908  TRP GLN GLU LEU ASP ASP ALA GLU LYS VAL GLN ARG GLU          
SEQRES  15 Z  908  PRO LEU LEU THR LEU VAL LYS GLU ILE VAL PRO TYR ASN          
SEQRES  16 Z  908  MET ALA HIS ASN ALA GLU HIS GLU ALA CYS ASP LEU LEU          
SEQRES  17 Z  908  MET GLU ILE GLU GLN VAL ASP MET LEU GLU LYS ASP ILE          
SEQRES  18 Z  908  ASP GLU ASN ALA TYR ALA LYS VAL CYS LEU TYR LEU THR          
SEQRES  19 Z  908  SER CYS VAL ASN TYR VAL PRO GLU PRO GLU ASN SER ALA          
SEQRES  20 Z  908  LEU LEU ARG CYS ALA LEU GLY VAL PHE ARG LYS PHE SER          
SEQRES  21 Z  908  ARG PHE PRO GLU ALA LEU ARG LEU ALA LEU MET LEU ASN          
SEQRES  22 Z  908  ASP MET GLU LEU VAL GLU ASP ILE PHE THR SER CYS LYS          
SEQRES  23 Z  908  ASP VAL VAL VAL GLN LYS GLN MET ALA PHE MET LEU GLY          
SEQRES  24 Z  908  ARG HIS GLY VAL PHE LEU GLU LEU SER GLU ASP VAL GLU          
SEQRES  25 Z  908  GLU TYR GLU ASP LEU THR GLU ILE MET SER ASN VAL GLN          
SEQRES  26 Z  908  LEU ASN SER ASN PHE LEU ALA LEU ALA ARG GLU LEU ASP          
SEQRES  27 Z  908  ILE MET GLU PRO LYS VAL PRO ASP ASP ILE TYR LYS THR          
SEQRES  28 Z  908  HIS LEU GLU ASN ASN ARG PHE GLY GLY SER GLY SER GLN          
SEQRES  29 Z  908  VAL ASP SER ALA ARG MET ASN LEU ALA SER SER PHE VAL          
SEQRES  30 Z  908  ASN GLY PHE VAL ASN ALA ALA PHE GLY GLN ASP LYS LEU          
SEQRES  31 Z  908  LEU THR ASP ASP GLY ASN LYS TRP LEU TYR LYS ASN LYS          
SEQRES  32 Z  908  ASP HIS GLY MET LEU SER ALA ALA ALA SER LEU GLY MET          
SEQRES  33 Z  908  ILE LEU LEU TRP ASP VAL ASP GLY GLY LEU THR GLN ILE          
SEQRES  34 Z  908  ASP LYS TYR LEU TYR SER SER GLU ASP TYR ILE LYS SER          
SEQRES  35 Z  908  GLY ALA LEU LEU ALA CYS GLY ILE VAL ASN SER GLY VAL          
SEQRES  36 Z  908  ARG ASN GLU CYS ASP PRO ALA LEU ALA LEU LEU SER ASP          
SEQRES  37 Z  908  TYR VAL LEU HIS ASN SER ASN THR MET ARG LEU GLY SER          
SEQRES  38 Z  908  ILE PHE GLY LEU GLY LEU ALA TYR ALA GLY SER ASN ARG          
SEQRES  39 Z  908  GLU ASP VAL LEU THR LEU LEU LEU PRO VAL MET GLY ASP          
SEQRES  40 Z  908  SER LYS SER SER MET GLU VAL ALA GLY VAL THR ALA LEU          
SEQRES  41 Z  908  ALA CYS GLY MET ILE ALA VAL GLY SER CYS ASN GLY ASP          
SEQRES  42 Z  908  VAL THR SER THR ILE LEU GLN THR ILE MET GLU LYS SER          
SEQRES  43 Z  908  GLU THR GLU LEU LYS ASP THR TYR ALA ARG TRP LEU PRO          
SEQRES  44 Z  908  LEU GLY LEU GLY LEU ASN HIS LEU GLY LYS GLY GLU ALA          
SEQRES  45 Z  908  ILE GLU ALA ILE LEU ALA ALA LEU GLU VAL VAL SER GLU          
SEQRES  46 Z  908  PRO PHE ARG SER PHE ALA ASN THR LEU VAL ASP VAL CYS          
SEQRES  47 Z  908  ALA TYR ALA GLY SER GLY ASN VAL LEU LYS VAL GLN GLN          
SEQRES  48 Z  908  LEU LEU HIS ILE CYS SER GLU HIS PHE ASP SER LYS GLU          
SEQRES  49 Z  908  LYS GLU GLU ASP LYS ASP LYS LYS GLU LYS LYS ASP LYS          
SEQRES  50 Z  908  ASP LYS LYS GLU ALA PRO ALA ASP MET GLY ALA HIS GLN          
SEQRES  51 Z  908  GLY VAL ALA VAL LEU GLY ILE ALA LEU ILE ALA MET GLY          
SEQRES  52 Z  908  GLU GLU ILE GLY ALA GLU MET ALA LEU ARG THR PHE GLY          
SEQRES  53 Z  908  HIS LEU LEU ARG TYR GLY GLU PRO THR LEU ARG ARG ALA          
SEQRES  54 Z  908  VAL PRO LEU ALA LEU ALA LEU ILE SER VAL SER ASN PRO          
SEQRES  55 Z  908  ARG LEU ASN ILE LEU ASP THR LEU SER LYS PHE SER HIS          
SEQRES  56 Z  908  ASP ALA ASP PRO GLU VAL SER TYR ASN SER ILE PHE ALA          
SEQRES  57 Z  908  MET GLY MET VAL GLY SER GLY THR ASN ASN ALA ARG LEU          
SEQRES  58 Z  908  ALA ALA MET LEU ARG GLN LEU ALA GLN TYR HIS ALA LYS          
SEQRES  59 Z  908  ASP PRO ASN ASN LEU PHE MET VAL ARG LEU ALA GLN GLY          
SEQRES  60 Z  908  LEU THR HIS LEU GLY LYS GLY THR LEU THR LEU CYS PRO          
SEQRES  61 Z  908  TYR HIS SER ASP ARG GLN LEU MET SER GLN VAL ALA VAL          
SEQRES  62 Z  908  ALA GLY LEU LEU THR VAL LEU VAL SER PHE LEU ASP VAL          
SEQRES  63 Z  908  ARG ASN ILE ILE LEU GLY LYS SER HIS TYR VAL LEU TYR          
SEQRES  64 Z  908  GLY LEU VAL ALA ALA MET GLN PRO ARG MET LEU VAL THR          
SEQRES  65 Z  908  PHE ASP GLU GLU LEU ARG PRO LEU PRO VAL SER VAL ARG          
SEQRES  66 Z  908  VAL GLY GLN ALA VAL ASP VAL VAL GLY GLN ALA GLY LYS          
SEQRES  67 Z  908  PRO LYS THR ILE THR GLY PHE GLN THR HIS THR THR PRO          
SEQRES  68 Z  908  VAL LEU LEU ALA HIS GLY GLU ARG ALA GLU LEU ALA THR          
SEQRES  69 Z  908  GLU GLU PHE LEU PRO VAL THR PRO ILE LEU GLU GLY PHE          
SEQRES  70 Z  908  VAL ILE LEU ARG LYS ASN PRO ASN TYR ASP LEU                  
SEQRES   1 1  239  MET ALA ALA THR LEU LEU ALA ALA ARG GLY ALA GLY PRO          
SEQRES   2 1  239  ALA PRO ALA TRP GLY PRO GLU ALA PHE THR PRO ASP TRP          
SEQRES   3 1  239  GLU SER ARG GLU VAL SER THR GLY THR THR ILE MET ALA          
SEQRES   4 1  239  VAL GLN PHE ASP GLY GLY VAL VAL LEU GLY ALA ASP SER          
SEQRES   5 1  239  ARG THR THR THR GLY SER TYR ILE ALA ASN ARG VAL THR          
SEQRES   6 1  239  ASP LYS LEU THR PRO ILE HIS ASP ARG ILE PHE CYS CYS          
SEQRES   7 1  239  ARG SER GLY SER ALA ALA ASP THR GLN ALA VAL ALA ASP          
SEQRES   8 1  239  ALA VAL THR TYR GLN LEU GLY PHE HIS SER ILE GLU LEU          
SEQRES   9 1  239  ASN GLU PRO PRO LEU VAL HIS THR ALA ALA SER LEU PHE          
SEQRES  10 1  239  LYS GLU MET CYS TYR ARG TYR ARG GLU ASP LEU MET ALA          
SEQRES  11 1  239  GLY ILE ILE ILE ALA GLY TRP ASP PRO GLN GLU GLY GLY          
SEQRES  12 1  239  GLN VAL TYR SER VAL PRO MET GLY GLY MET MET VAL ARG          
SEQRES  13 1  239  GLN SER PHE ALA ILE GLY GLY SER GLY SER SER TYR ILE          
SEQRES  14 1  239  TYR GLY TYR VAL ASP ALA THR TYR ARG GLU GLY MET THR          
SEQRES  15 1  239  LYS GLU GLU CYS LEU GLN PHE THR ALA ASN ALA LEU ALA          
SEQRES  16 1  239  LEU ALA MET GLU ARG ASP GLY SER SER GLY GLY VAL ILE          
SEQRES  17 1  239  ARG LEU ALA ALA ILE ALA GLU SER GLY VAL GLU ARG GLN          
SEQRES  18 1  239  VAL LEU LEU GLY ASP GLN ILE PRO LYS PHE ALA VAL ALA          
SEQRES  19 1  239  THR LEU PRO PRO ALA                                          
SEQRES   1 2  277  MET ALA ALA VAL SER VAL TYR ALA PRO PRO VAL GLY GLY          
SEQRES   2 2  277  PHE SER PHE ASP ASN CYS ARG ARG ASN ALA VAL LEU GLU          
SEQRES   3 2  277  ALA ASP PHE ALA LYS ARG GLY TYR LYS LEU PRO LYS VAL          
SEQRES   4 2  277  ARG LYS THR GLY THR THR ILE ALA GLY VAL VAL TYR LYS          
SEQRES   5 2  277  ASP GLY ILE VAL LEU GLY ALA ASP THR ARG ALA THR GLU          
SEQRES   6 2  277  GLY MET VAL VAL ALA ASP LYS ASN CYS SER LYS ILE HIS          
SEQRES   7 2  277  PHE ILE SER PRO ASN ILE TYR CYS CYS GLY ALA GLY THR          
SEQRES   8 2  277  ALA ALA ASP THR ASP MET THR THR GLN LEU ILE SER SER          
SEQRES   9 2  277  ASN LEU GLU LEU HIS SER LEU SER THR GLY ARG LEU PRO          
SEQRES  10 2  277  ARG VAL VAL THR ALA ASN ARG MET LEU LYS GLN MET LEU          
SEQRES  11 2  277  PHE ARG TYR GLN GLY TYR ILE GLY ALA ALA LEU VAL LEU          
SEQRES  12 2  277  GLY GLY VAL ASP VAL THR GLY PRO HIS LEU TYR SER ILE          
SEQRES  13 2  277  TYR PRO HIS GLY SER THR ASP LYS LEU PRO TYR VAL THR          
SEQRES  14 2  277  MET GLY SER GLY SER LEU ALA ALA MET ALA VAL PHE GLU          
SEQRES  15 2  277  ASP LYS PHE ARG PRO ASP MET GLU GLU GLU GLU ALA LYS          
SEQRES  16 2  277  ASN LEU VAL SER GLU ALA ILE ALA ALA GLY ILE PHE ASN          
SEQRES  17 2  277  ASP LEU GLY SER GLY SER ASN ILE ASP LEU CYS VAL ILE          
SEQRES  18 2  277  SER LYS ASN LYS LEU ASP PHE LEU ARG PRO TYR THR VAL          
SEQRES  19 2  277  PRO ASN LYS LYS GLY THR ARG LEU GLY ARG TYR ARG CYS          
SEQRES  20 2  277  GLU LYS GLY THR THR ALA VAL LEU THR GLU LYS ILE THR          
SEQRES  21 2  277  PRO LEU GLU ILE GLU VAL LEU GLU GLU THR VAL GLN THR          
SEQRES  22 2  277  MET ASP THR SER                                              
SEQRES   1 3  205  MET SER ILE MET SER TYR ASN GLY GLY ALA VAL MET ALA          
SEQRES   2 3  205  MET LYS GLY LYS ASN CYS VAL ALA ILE ALA ALA ASP ARG          
SEQRES   3 3  205  ARG PHE GLY ILE GLN ALA GLN MET VAL THR THR ASP PHE          
SEQRES   4 3  205  GLN LYS ILE PHE PRO MET GLY ASP ARG LEU TYR ILE GLY          
SEQRES   5 3  205  LEU ALA GLY LEU ALA THR ASP VAL GLN THR VAL ALA GLN          
SEQRES   6 3  205  ARG LEU LYS PHE ARG LEU ASN LEU TYR GLU LEU LYS GLU          
SEQRES   7 3  205  GLY ARG GLN ILE LYS PRO TYR THR LEU MET SER MET VAL          
SEQRES   8 3  205  ALA ASN LEU LEU TYR GLU LYS ARG PHE GLY PRO TYR TYR          
SEQRES   9 3  205  THR GLU PRO VAL ILE ALA GLY LEU ASP PRO LYS THR PHE          
SEQRES  10 3  205  LYS PRO PHE ILE CYS SER LEU ASP LEU ILE GLY CYS PRO          
SEQRES  11 3  205  MET VAL THR ASP ASP PHE VAL VAL SER GLY THR CYS ALA          
SEQRES  12 3  205  GLU GLN MET TYR GLY MET CYS GLU SER LEU TRP GLU PRO          
SEQRES  13 3  205  ASN MET ASP PRO ASP HIS LEU PHE GLU THR ILE SER GLN          
SEQRES  14 3  205  ALA MET LEU ASN ALA VAL ASP ARG ASP ALA VAL SER GLY          
SEQRES  15 3  205  MET GLY VAL ILE VAL HIS ILE ILE GLU LYS ASP LYS ILE          
SEQRES  16 3  205  THR THR ARG THR LEU LYS ALA ARG MET ASP                      
SEQRES   1 4  201  MET GLU TYR LEU ILE GLY ILE GLN GLY PRO ASP TYR VAL          
SEQRES   2 4  201  LEU VAL ALA SER ASP ARG VAL ALA ALA SER ASN ILE VAL          
SEQRES   3 4  201  GLN MET LYS ASP ASP HIS ASP LYS MET PHE LYS MET SER          
SEQRES   4 4  201  GLU LYS ILE LEU LEU LEU CYS VAL GLY GLU ALA GLY ASP          
SEQRES   5 4  201  THR VAL GLN PHE ALA GLU TYR ILE GLN LYS ASN VAL GLN          
SEQRES   6 4  201  LEU TYR LYS MET ARG ASN GLY TYR GLU LEU SER PRO THR          
SEQRES   7 4  201  ALA ALA ALA ASN PHE THR ARG ARG ASN LEU ALA ASP CYS          
SEQRES   8 4  201  LEU ARG SER ARG THR PRO TYR HIS VAL ASN LEU LEU LEU          
SEQRES   9 4  201  ALA GLY TYR ASP GLU HIS GLU GLY PRO ALA LEU TYR TYR          
SEQRES  10 4  201  MET ASP TYR LEU ALA ALA LEU ALA LYS ALA PRO PHE ALA          
SEQRES  11 4  201  ALA HIS GLY TYR GLY ALA PHE LEU THR LEU SER ILE LEU          
SEQRES  12 4  201  ASP ARG TYR TYR THR PRO THR ILE SER ARG GLU ARG ALA          
SEQRES  13 4  201  VAL GLU LEU LEU ARG LYS CYS LEU GLU GLU LEU GLN LYS          
SEQRES  14 4  201  ARG PHE ILE LEU ASN LEU PRO THR PHE SER VAL ARG ILE          
SEQRES  15 4  201  ILE ASP LYS ASN GLY ILE HIS ASP LEU ASP ASN ILE SER          
SEQRES  16 4  201  PHE PRO LYS GLN GLY SER                                      
SEQRES   1 5  263  MET ALA LEU ALA SER VAL LEU GLU ARG PRO LEU PRO VAL          
SEQRES   2 5  263  ASN GLN ARG GLY PHE PHE GLY LEU GLY GLY ARG ALA ASP          
SEQRES   3 5  263  LEU LEU ASP LEU GLY PRO GLY SER LEU SER ASP GLY LEU          
SEQRES   4 5  263  SER LEU ALA ALA PRO GLY TRP GLY VAL PRO GLU GLU PRO          
SEQRES   5 5  263  GLY ILE GLU MET LEU HIS GLY THR THR THR LEU ALA PHE          
SEQRES   6 5  263  LYS PHE ARG HIS GLY VAL ILE VAL ALA ALA ASP SER ARG          
SEQRES   7 5  263  ALA THR ALA GLY ALA TYR ILE ALA SER GLN THR VAL LYS          
SEQRES   8 5  263  LYS VAL ILE GLU ILE ASN PRO TYR LEU LEU GLY THR MET          
SEQRES   9 5  263  ALA GLY GLY ALA ALA ASP CYS SER PHE TRP GLU ARG LEU          
SEQRES  10 5  263  LEU ALA ARG GLN CYS ARG ILE TYR GLU LEU ARG ASN LYS          
SEQRES  11 5  263  GLU ARG ILE SER VAL ALA ALA ALA SER LYS LEU LEU ALA          
SEQRES  12 5  263  ASN MET VAL TYR GLN TYR LYS GLY MET GLY LEU SER MET          
SEQRES  13 5  263  GLY THR MET ILE CYS GLY TRP ASP LYS ARG GLY PRO GLY          
SEQRES  14 5  263  LEU TYR TYR VAL ASP SER GLU GLY ASN ARG ILE SER GLY          
SEQRES  15 5  263  ALA THR PHE SER VAL GLY SER GLY SER VAL TYR ALA TYR          
SEQRES  16 5  263  GLY VAL MET ASP ARG GLY TYR SER TYR ASP LEU GLU VAL          
SEQRES  17 5  263  GLU GLN ALA TYR ASP LEU ALA ARG ARG ALA ILE TYR GLN          
SEQRES  18 5  263  ALA THR TYR ARG ASP ALA TYR SER GLY GLY ALA VAL ASN          
SEQRES  19 5  263  LEU TYR HIS VAL ARG GLU ASP GLY TRP ILE ARG VAL SER          
SEQRES  20 5  263  SER ASP ASN VAL ALA ASP LEU HIS GLU LYS TYR SER GLY          
SEQRES  21 5  263  SER THR PRO                                                  
SEQRES   1 6  241  MET LEU SER SER THR ALA MET TYR SER ALA PRO GLY ARG          
SEQRES   2 6  241  ASP LEU GLY MET GLU PRO HIS ARG ALA ALA GLY PRO LEU          
SEQRES   3 6  241  GLN LEU ARG PHE SER PRO TYR VAL PHE ASN GLY GLY THR          
SEQRES   4 6  241  ILE LEU ALA ILE ALA GLY GLU ASP PHE ALA ILE VAL ALA          
SEQRES   5 6  241  SER ASP THR ARG LEU SER GLU GLY PHE SER ILE HIS THR          
SEQRES   6 6  241  ARG ASP SER PRO LYS CYS TYR LYS LEU THR ASP LYS THR          
SEQRES   7 6  241  VAL ILE GLY CYS SER GLY PHE HIS GLY ASP CYS LEU THR          
SEQRES   8 6  241  LEU THR LYS ILE ILE GLU ALA ARG LEU LYS MET TYR LYS          
SEQRES   9 6  241  HIS SER ASN ASN LYS ALA MET THR THR GLY ALA ILE ALA          
SEQRES  10 6  241  ALA MET LEU SER THR ILE LEU TYR SER ARG ARG PHE PHE          
SEQRES  11 6  241  PRO TYR TYR VAL TYR ASN ILE ILE GLY GLY LEU ASP GLU          
SEQRES  12 6  241  GLU GLY LYS GLY ALA VAL TYR SER PHE ASP PRO VAL GLY          
SEQRES  13 6  241  SER TYR GLN ARG ASP SER PHE LYS ALA GLY GLY SER ALA          
SEQRES  14 6  241  SER ALA MET LEU GLN PRO LEU LEU ASP ASN GLN VAL GLY          
SEQRES  15 6  241  PHE LYS ASN MET GLN ASN VAL GLU HIS VAL PRO LEU SER          
SEQRES  16 6  241  LEU ASP ARG ALA MET ARG LEU VAL LYS ASP VAL PHE ILE          
SEQRES  17 6  241  SER ALA ALA GLU ARG ASP VAL TYR THR GLY ASP ALA LEU          
SEQRES  18 6  241  ARG ILE CYS ILE VAL THR LYS GLU GLY ILE ARG GLU GLU          
SEQRES  19 6  241  THR VAL SER LEU ARG LYS ASP                                  
SEQRES   1 7  264  MET GLU ALA PHE LEU GLY SER ARG SER GLY LEU TRP ALA          
SEQRES   2 7  264  GLY GLY PRO ALA PRO GLY GLN PHE TYR ARG ILE PRO SER          
SEQRES   3 7  264  THR PRO ASP SER PHE MET ASP PRO ALA SER ALA LEU TYR          
SEQRES   4 7  264  ARG GLY PRO ILE THR ARG THR GLN ASN PRO MET VAL THR          
SEQRES   5 7  264  GLY THR SER VAL LEU GLY VAL LYS PHE GLU GLY GLY VAL          
SEQRES   6 7  264  VAL ILE ALA ALA ASP MET LEU GLY SER TYR GLY SER LEU          
SEQRES   7 7  264  ALA ARG PHE ARG ASN ILE SER ARG ILE MET ARG VAL ASN          
SEQRES   8 7  264  ASN SER THR MET LEU GLY ALA SER GLY ASP TYR ALA ASP          
SEQRES   9 7  264  PHE GLN TYR LEU LYS GLN VAL LEU GLY GLN MET VAL ILE          
SEQRES  10 7  264  ASP GLU GLU LEU LEU GLY ASP GLY HIS SER TYR SER PRO          
SEQRES  11 7  264  ARG ALA ILE HIS SER TRP LEU THR ARG ALA MET TYR SER          
SEQRES  12 7  264  ARG ARG SER LYS MET ASN PRO LEU TRP ASN THR MET VAL          
SEQRES  13 7  264  ILE GLY GLY TYR ALA ASP GLY GLU SER PHE LEU GLY TYR          
SEQRES  14 7  264  VAL ASP MET LEU GLY VAL ALA TYR GLU ALA PRO SER LEU          
SEQRES  15 7  264  ALA THR GLY TYR GLY ALA TYR LEU ALA GLN PRO LEU LEU          
SEQRES  16 7  264  ARG GLU VAL LEU GLU LYS GLN PRO VAL LEU SER GLN THR          
SEQRES  17 7  264  GLU ALA ARG ASP LEU VAL GLU ARG CYS MET ARG VAL LEU          
SEQRES  18 7  264  TYR TYR ARG ASP ALA ARG SER TYR ASN ARG PHE GLN ILE          
SEQRES  19 7  264  ALA THR VAL THR GLU LYS GLY VAL GLU ILE GLU GLY PRO          
SEQRES  20 7  264  LEU SER THR GLU THR ASN TRP ASP ILE ALA HIS MET ILE          
SEQRES  21 7  264  SER GLY PHE GLU                                              
SEQRES   1 A  246  MET SER ARG GLY SER SER ALA GLY PHE ASP ARG HIS ILE          
SEQRES   2 A  246  THR ILE PHE SER PRO GLU GLY ARG LEU TYR GLN VAL GLU          
SEQRES   3 A  246  TYR ALA PHE LYS ALA ILE ASN GLN GLY GLY LEU THR SER          
SEQRES   4 A  246  VAL ALA VAL ARG GLY LYS ASP CYS ALA VAL ILE VAL THR          
SEQRES   5 A  246  GLN LYS LYS VAL PRO ASP LYS LEU LEU ASP SER SER THR          
SEQRES   6 A  246  VAL THR HIS LEU PHE LYS ILE THR GLU ASN ILE GLY CYS          
SEQRES   7 A  246  VAL MET THR GLY MET THR ALA ASP SER ARG SER GLN VAL          
SEQRES   8 A  246  GLN ARG ALA ARG TYR GLU ALA ALA ASN TRP LYS TYR LYS          
SEQRES   9 A  246  TYR GLY TYR GLU ILE PRO VAL ASP MET LEU CYS LYS ARG          
SEQRES  10 A  246  ILE ALA ASP ILE SER GLN VAL TYR THR GLN ASN ALA GLU          
SEQRES  11 A  246  MET ARG PRO LEU GLY CYS CYS MET ILE LEU ILE GLY ILE          
SEQRES  12 A  246  ASP GLU GLU GLN GLY PRO GLN VAL TYR LYS CYS ASP PRO          
SEQRES  13 A  246  ALA GLY TYR TYR CYS GLY PHE LYS ALA THR ALA ALA GLY          
SEQRES  14 A  246  VAL LYS GLN THR GLU SER THR SER PHE LEU GLU LYS LYS          
SEQRES  15 A  246  VAL LYS LYS LYS PHE ASP TRP THR PHE GLU GLN THR VAL          
SEQRES  16 A  246  GLU THR ALA ILE THR CYS LEU SER THR VAL LEU SER ILE          
SEQRES  17 A  246  ASP PHE LYS PRO SER GLU ILE GLU VAL GLY VAL VAL THR          
SEQRES  18 A  246  VAL GLU ASN PRO LYS PHE ARG ILE LEU THR GLU ALA GLU          
SEQRES  19 A  246  ILE ASP ALA HIS LEU VAL ALA LEU ALA GLU ARG ASP              
SEQRES   1 B  234  MET ALA GLU ARG GLY TYR SER PHE SER LEU THR THR PHE          
SEQRES   2 B  234  SER PRO SER GLY LYS LEU VAL GLN ILE GLU TYR ALA LEU          
SEQRES   3 B  234  ALA ALA VAL ALA GLY GLY ALA PRO SER VAL GLY ILE LYS          
SEQRES   4 B  234  ALA ALA ASN GLY VAL VAL LEU ALA THR GLU LYS LYS GLN          
SEQRES   5 B  234  LYS SER ILE LEU TYR ASP GLU ARG SER VAL HIS LYS VAL          
SEQRES   6 B  234  GLU PRO ILE THR LYS HIS ILE GLY LEU VAL TYR SER GLY          
SEQRES   7 B  234  MET GLY PRO ASP TYR ARG VAL LEU VAL HIS ARG ALA ARG          
SEQRES   8 B  234  LYS LEU ALA GLN GLN TYR TYR LEU VAL TYR GLN GLU PRO          
SEQRES   9 B  234  ILE PRO THR ALA GLN LEU VAL GLN ARG VAL ALA SER VAL          
SEQRES  10 B  234  MET GLN GLU TYR THR GLN SER GLY GLY VAL ARG PRO PHE          
SEQRES  11 B  234  GLY VAL SER LEU LEU ILE CYS GLY TRP ASN GLU GLY ARG          
SEQRES  12 B  234  PRO TYR LEU PHE GLN SER ASP PRO SER GLY ALA TYR PHE          
SEQRES  13 B  234  ALA TRP LYS ALA THR ALA MET GLY LYS ASN TYR VAL ASN          
SEQRES  14 B  234  GLY LYS THR PHE LEU GLU LYS ARG TYR ASN GLU ASP LEU          
SEQRES  15 B  234  GLU LEU GLU ASP ALA ILE HIS THR ALA ILE LEU THR LEU          
SEQRES  16 B  234  LYS GLU SER PHE GLU GLY GLN MET THR GLU ASP ASN ILE          
SEQRES  17 B  234  GLU VAL GLY ILE CYS ASN GLU ALA GLY PHE ARG ARG LEU          
SEQRES  18 B  234  THR PRO THR GLU VAL LYS ASP TYR LEU ALA ALA ILE ALA          
SEQRES   1 C  261  MET SER ARG ARG TYR ASP SER ARG THR THR ILE PHE SER          
SEQRES   2 C  261  PRO GLU GLY ARG LEU TYR GLN VAL GLU TYR ALA MET GLU          
SEQRES   3 C  261  ALA ILE GLY HIS ALA GLY THR CYS LEU GLY ILE LEU ALA          
SEQRES   4 C  261  ASN ASP GLY VAL LEU LEU ALA ALA GLU ARG ARG ASN ILE          
SEQRES   5 C  261  HIS LYS LEU LEU ASP GLU VAL PHE PHE SER GLU LYS ILE          
SEQRES   6 C  261  TYR LYS LEU ASN GLU ASP MET ALA CYS SER VAL ALA GLY          
SEQRES   7 C  261  ILE THR SER ASP ALA ASN VAL LEU THR ASN GLU LEU ARG          
SEQRES   8 C  261  LEU ILE ALA GLN ARG TYR LEU LEU GLN TYR GLN GLU PRO          
SEQRES   9 C  261  ILE PRO CYS GLU GLN LEU VAL THR ALA LEU CYS ASP ILE          
SEQRES  10 C  261  LYS GLN ALA TYR THR GLN PHE GLY GLY LYS ARG PRO PHE          
SEQRES  11 C  261  GLY VAL SER LEU LEU TYR ILE GLY TRP ASP LYS HIS TYR          
SEQRES  12 C  261  GLY PHE GLN LEU TYR GLN SER ASP PRO SER GLY ASN TYR          
SEQRES  13 C  261  GLY GLY TRP LYS ALA THR CYS ILE GLY ASN ASN SER ALA          
SEQRES  14 C  261  ALA ALA VAL SER MET LEU LYS GLN ASP TYR LYS GLU GLY          
SEQRES  15 C  261  GLU MET THR LEU LYS SER ALA LEU ALA LEU ALA ILE LYS          
SEQRES  16 C  261  VAL LEU ASN LYS THR MET ASP VAL SER LYS LEU SER ALA          
SEQRES  17 C  261  GLU LYS VAL GLU ILE ALA THR LEU THR ARG GLU ASN GLY          
SEQRES  18 C  261  LYS THR VAL ILE ARG VAL LEU LYS GLN LYS GLU VAL GLU          
SEQRES  19 C  261  GLN LEU ILE LYS LYS HIS GLU GLU GLU GLU ALA LYS ALA          
SEQRES  20 C  261  GLU ARG GLU LYS LYS GLU LYS GLU GLN LYS GLU LYS ASP          
SEQRES  21 C  261  LYS                                                          
SEQRES   1 D  248  MET SER TYR ASP ARG ALA ILE THR VAL PHE SER PRO ASP          
SEQRES   2 D  248  GLY HIS LEU PHE GLN VAL GLU TYR ALA GLN GLU ALA VAL          
SEQRES   3 D  248  LYS LYS GLY SER THR ALA VAL GLY VAL ARG GLY ARG ASP          
SEQRES   4 D  248  ILE VAL VAL LEU GLY VAL GLU LYS LYS SER VAL ALA LYS          
SEQRES   5 D  248  LEU GLN ASP GLU ARG THR VAL ARG LYS ILE CYS ALA LEU          
SEQRES   6 D  248  ASP ASP ASN VAL CYS MET ALA PHE ALA GLY LEU THR ALA          
SEQRES   7 D  248  ASP ALA ARG ILE VAL ILE ASN ARG ALA ARG VAL GLU CYS          
SEQRES   8 D  248  GLN SER HIS ARG LEU THR VAL GLU ASP PRO VAL THR VAL          
SEQRES   9 D  248  GLU TYR ILE THR ARG TYR ILE ALA SER LEU LYS GLN ARG          
SEQRES  10 D  248  TYR THR GLN SER ASN GLY ARG ARG PRO PHE GLY ILE SER          
SEQRES  11 D  248  ALA LEU ILE VAL GLY PHE ASP PHE ASP GLY THR PRO ARG          
SEQRES  12 D  248  LEU TYR GLN THR ASP PRO SER GLY THR TYR HIS ALA TRP          
SEQRES  13 D  248  LYS ALA ASN ALA ILE GLY ARG GLY ALA LYS SER VAL ARG          
SEQRES  14 D  248  GLU PHE LEU GLU LYS ASN TYR THR ASP GLU ALA ILE GLU          
SEQRES  15 D  248  THR ASP ASP LEU THR ILE LYS LEU VAL ILE LYS ALA LEU          
SEQRES  16 D  248  LEU GLU VAL VAL GLN SER GLY GLY LYS ASN ILE GLU LEU          
SEQRES  17 D  248  ALA VAL MET ARG ARG ASP GLN SER LEU LYS ILE LEU ASN          
SEQRES  18 D  248  PRO GLU GLU ILE GLU LYS TYR VAL ALA GLU ILE GLU LYS          
SEQRES  19 D  248  GLU LYS GLU GLU ASN GLU LYS LYS LYS GLN LYS LYS ALA          
SEQRES  20 D  248  SER                                                          
SEQRES   1 E  241  MET PHE LEU THR ARG SER GLU TYR ASP ARG GLY VAL ASN          
SEQRES   2 E  241  THR PHE SER PRO GLU GLY ARG LEU PHE GLN VAL GLU TYR          
SEQRES   3 E  241  ALA ILE GLU ALA ILE LYS LEU GLY SER THR ALA ILE GLY          
SEQRES   4 E  241  ILE GLN THR SER GLU GLY VAL CYS LEU ALA VAL GLU LYS          
SEQRES   5 E  241  ARG ILE THR SER PRO LEU MET GLU PRO SER SER ILE GLU          
SEQRES   6 E  241  LYS ILE VAL GLU ILE ASP ALA HIS ILE GLY CYS ALA MET          
SEQRES   7 E  241  SER GLY LEU ILE ALA ASP ALA LYS THR LEU ILE ASP LYS          
SEQRES   8 E  241  ALA ARG VAL GLU THR GLN ASN HIS TRP PHE THR TYR ASN          
SEQRES   9 E  241  GLU THR MET THR VAL GLU SER VAL THR GLN ALA VAL SER          
SEQRES  10 E  241  ASN LEU ALA LEU GLN PHE GLY GLU GLU ASP ALA ASP PRO          
SEQRES  11 E  241  GLY ALA MET SER ARG PRO PHE GLY VAL ALA LEU LEU PHE          
SEQRES  12 E  241  GLY GLY VAL ASP GLU LYS GLY PRO GLN LEU PHE HIS MET          
SEQRES  13 E  241  ASP PRO SER GLY THR PHE VAL GLN CYS ASP ALA ARG ALA          
SEQRES  14 E  241  ILE GLY SER ALA SER GLU GLY ALA GLN SER SER LEU GLN          
SEQRES  15 E  241  GLU VAL TYR HIS LYS SER MET THR LEU LYS GLU ALA ILE          
SEQRES  16 E  241  LYS SER SER LEU ILE ILE LEU LYS GLN VAL MET GLU GLU          
SEQRES  17 E  241  LYS LEU ASN ALA THR ASN ILE GLU LEU ALA THR VAL GLN          
SEQRES  18 E  241  PRO GLY GLN ASN PHE HIS MET PHE THR LYS GLU GLU LEU          
SEQRES  19 E  241  GLU GLU VAL ILE LYS ASP ILE                                  
SEQRES   1 F  263  MET PHE ARG ASN GLN TYR ASP ASN ASP VAL THR VAL TRP          
SEQRES   2 F  263  SER PRO GLN GLY ARG ILE HIS GLN ILE GLU TYR ALA MET          
SEQRES   3 F  263  GLU ALA VAL LYS GLN GLY SER ALA THR VAL GLY LEU LYS          
SEQRES   4 F  263  SER LYS THR HIS ALA VAL LEU VAL ALA LEU LYS ARG ALA          
SEQRES   5 F  263  GLN SER GLU LEU ALA ALA HIS GLN LYS LYS ILE LEU HIS          
SEQRES   6 F  263  VAL ASP ASN HIS ILE GLY ILE SER ILE ALA GLY LEU THR          
SEQRES   7 F  263  ALA ASP ALA ARG LEU LEU CYS ASN PHE MET ARG GLN GLU          
SEQRES   8 F  263  CYS LEU ASP SER ARG PHE VAL PHE ASP ARG PRO LEU PRO          
SEQRES   9 F  263  VAL SER ARG LEU VAL SER LEU ILE GLY SER LYS THR GLN          
SEQRES  10 F  263  ILE PRO THR GLN ARG TYR GLY ARG ARG PRO TYR GLY VAL          
SEQRES  11 F  263  GLY LEU LEU ILE ALA GLY TYR ASP ASP MET GLY PRO HIS          
SEQRES  12 F  263  ILE PHE GLN THR CYS PRO SER ALA ASN TYR PHE ASP CYS          
SEQRES  13 F  263  ARG ALA MET SER ILE GLY ALA ARG SER GLN SER ALA ARG          
SEQRES  14 F  263  THR TYR LEU GLU ARG HIS MET SER GLU PHE MET GLU CYS          
SEQRES  15 F  263  ASN LEU ASN GLU LEU VAL LYS HIS GLY LEU ARG ALA LEU          
SEQRES  16 F  263  ARG GLU THR LEU PRO ALA GLU GLN ASP LEU THR THR LYS          
SEQRES  17 F  263  ASN VAL SER ILE GLY ILE VAL GLY LYS ASP LEU GLU PHE          
SEQRES  18 F  263  THR ILE TYR ASP ASP ASP ASP VAL SER PRO PHE LEU GLU          
SEQRES  19 F  263  GLY LEU GLU GLU ARG PRO GLN ARG LYS ALA GLN PRO ALA          
SEQRES  20 F  263  GLN PRO ALA ASP GLU PRO ALA GLU LYS ALA ASP GLU PRO          
SEQRES  21 F  263  MET GLU HIS                                                  
SEQRES   1 G  255  MET SER SER ILE GLY THR GLY TYR ASP LEU SER ALA SER          
SEQRES   2 G  255  THR PHE SER PRO ASP GLY ARG VAL PHE GLN VAL GLU TYR          
SEQRES   3 G  255  ALA MET LYS ALA VAL GLU ASN SER SER THR ALA ILE GLY          
SEQRES   4 G  255  ILE ARG CYS LYS ASP GLY VAL VAL PHE GLY VAL GLU LYS          
SEQRES   5 G  255  LEU VAL LEU SER LYS LEU TYR GLU GLU GLY SER ASN LYS          
SEQRES   6 G  255  ARG LEU PHE ASN VAL ASP ARG HIS VAL GLY MET ALA VAL          
SEQRES   7 G  255  ALA GLY LEU LEU ALA ASP ALA ARG SER LEU ALA ASP ILE          
SEQRES   8 G  255  ALA ARG GLU GLU ALA SER ASN PHE ARG SER ASN PHE GLY          
SEQRES   9 G  255  TYR ASN ILE PRO LEU LYS HIS LEU ALA ASP ARG VAL ALA          
SEQRES  10 G  255  MET TYR VAL HIS ALA TYR THR LEU TYR SER ALA VAL ARG          
SEQRES  11 G  255  PRO PHE GLY CYS SER PHE MET LEU GLY SER TYR SER VAL          
SEQRES  12 G  255  ASN ASP GLY ALA GLN LEU TYR MET ILE ASP PRO SER GLY          
SEQRES  13 G  255  VAL SER TYR GLY TYR TRP GLY CYS ALA ILE GLY LYS ALA          
SEQRES  14 G  255  ARG GLN ALA ALA LYS THR GLU ILE GLU LYS LEU GLN MET          
SEQRES  15 G  255  LYS GLU MET THR CYS ARG ASP ILE VAL LYS GLU VAL ALA          
SEQRES  16 G  255  LYS ILE ILE TYR ILE VAL HIS ASP GLU VAL LYS ASP LYS          
SEQRES  17 G  255  ALA PHE GLU LEU GLU LEU SER TRP VAL GLY GLU LEU THR          
SEQRES  18 G  255  ASN GLY ARG HIS GLU ILE VAL PRO LYS ASP ILE ARG GLU          
SEQRES  19 G  255  GLU ALA GLU LYS TYR ALA LYS GLU SER LEU LYS GLU GLU          
SEQRES  20 G  255  ASP GLU SER ASP ASP ASP ASN MET                              
SEQRES   1 H  433  MET PRO ASP TYR LEU GLY ALA ASP GLN ARG LYS THR LYS          
SEQRES   2 H  433  GLU ASP GLU LYS ASP ASP LYS PRO ILE ARG ALA LEU ASP          
SEQRES   3 H  433  GLU GLY ASP ILE ALA LEU LEU LYS THR TYR GLY GLN SER          
SEQRES   4 H  433  THR TYR SER ARG GLN ILE LYS GLN VAL GLU ASP ASP ILE          
SEQRES   5 H  433  GLN GLN LEU LEU LYS LYS ILE ASN GLU LEU THR GLY ILE          
SEQRES   6 H  433  LYS GLU SER ASP THR GLY LEU ALA PRO PRO ALA LEU TRP          
SEQRES   7 H  433  ASP LEU ALA ALA ASP LYS GLN THR LEU GLN SER GLU GLN          
SEQRES   8 H  433  PRO LEU GLN VAL ALA ARG CYS THR LYS ILE ILE ASN ALA          
SEQRES   9 H  433  ASP SER GLU ASP PRO LYS TYR ILE ILE ASN VAL LYS GLN          
SEQRES  10 H  433  PHE ALA LYS PHE VAL VAL ASP LEU SER ASP GLN VAL ALA          
SEQRES  11 H  433  PRO THR ASP ILE GLU GLU GLY MET ARG VAL GLY VAL ASP          
SEQRES  12 H  433  ARG ASN LYS TYR GLN ILE HIS ILE PRO LEU PRO PRO LYS          
SEQRES  13 H  433  ILE ASP PRO THR VAL THR MET MET GLN VAL GLU GLU LYS          
SEQRES  14 H  433  PRO ASP VAL THR TYR SER ASP VAL GLY GLY CYS LYS GLU          
SEQRES  15 H  433  GLN ILE GLU LYS LEU ARG GLU VAL VAL GLU THR PRO LEU          
SEQRES  16 H  433  LEU HIS PRO GLU ARG PHE VAL ASN LEU GLY ILE GLU PRO          
SEQRES  17 H  433  PRO LYS GLY VAL LEU LEU PHE GLY PRO PRO GLY THR GLY          
SEQRES  18 H  433  LYS THR LEU CYS ALA ARG ALA VAL ALA ASN ARG THR ASP          
SEQRES  19 H  433  ALA CYS PHE ILE ARG VAL ILE GLY SER GLU LEU VAL GLN          
SEQRES  20 H  433  LYS TYR VAL GLY GLU GLY ALA ARG MET VAL ARG GLU LEU          
SEQRES  21 H  433  PHE GLU MET ALA ARG THR LYS LYS ALA CYS LEU ILE PHE          
SEQRES  22 H  433  PHE ASP GLU ILE ASP ALA ILE GLY GLY ALA ARG PHE ASP          
SEQRES  23 H  433  ASP GLY ALA GLY GLY ASP ASN GLU VAL GLN ARG THR MET          
SEQRES  24 H  433  LEU GLU LEU ILE ASN GLN LEU ASP GLY PHE ASP PRO ARG          
SEQRES  25 H  433  GLY ASN ILE LYS VAL LEU MET ALA THR ASN ARG PRO ASP          
SEQRES  26 H  433  THR LEU ASP PRO ALA LEU MET ARG PRO GLY ARG LEU ASP          
SEQRES  27 H  433  ARG LYS ILE GLU PHE SER LEU PRO ASP LEU GLU GLY ARG          
SEQRES  28 H  433  THR HIS ILE PHE LYS ILE HIS ALA ARG SER MET SER VAL          
SEQRES  29 H  433  GLU ARG ASP ILE ARG PHE GLU LEU LEU ALA ARG LEU CYS          
SEQRES  30 H  433  PRO ASN SER THR GLY ALA GLU ILE ARG SER VAL CYS THR          
SEQRES  31 H  433  GLU ALA GLY MET PHE ALA ILE ARG ALA ARG ARG LYS ILE          
SEQRES  32 H  433  ALA THR GLU LYS ASP PHE LEU GLU ALA VAL ASN LYS VAL          
SEQRES  33 H  433  ILE LYS SER TYR ALA LYS PHE SER ALA THR PRO ARG TYR          
SEQRES  34 H  433  MET THR TYR ASN                                              
SEQRES   1 I  440  MET GLY GLN SER GLN SER GLY GLY HIS GLY PRO GLY GLY          
SEQRES   2 I  440  GLY LYS LYS ASP ASP LYS ASP LYS LYS LYS LYS TYR GLU          
SEQRES   3 I  440  PRO PRO VAL PRO THR ARG VAL GLY LYS LYS LYS LYS LYS          
SEQRES   4 I  440  THR LYS GLY PRO ASP ALA ALA SER LYS LEU PRO LEU VAL          
SEQRES   5 I  440  THR PRO HIS THR GLN CYS ARG LEU LYS LEU LEU LYS LEU          
SEQRES   6 I  440  GLU ARG ILE LYS ASP TYR LEU LEU MET GLU GLU GLU PHE          
SEQRES   7 I  440  ILE ARG ASN GLN GLU GLN MET LYS PRO LEU GLU GLU LYS          
SEQRES   8 I  440  GLN GLU GLU GLU ARG SER LYS VAL ASP ASP LEU ARG GLY          
SEQRES   9 I  440  THR PRO MET SER VAL GLY THR LEU GLU GLU ILE ILE ASP          
SEQRES  10 I  440  ASP ASN HIS ALA ILE VAL SER THR SER VAL GLY SER GLU          
SEQRES  11 I  440  HIS TYR VAL SER ILE LEU SER PHE VAL ASP LYS ASP LEU          
SEQRES  12 I  440  LEU GLU PRO GLY CYS SER VAL LEU LEU ASN HIS LYS VAL          
SEQRES  13 I  440  HIS ALA VAL ILE GLY VAL LEU MET ASP ASP THR ASP PRO          
SEQRES  14 I  440  LEU VAL THR VAL MET LYS VAL GLU LYS ALA PRO GLN GLU          
SEQRES  15 I  440  THR TYR ALA ASP ILE GLY GLY LEU ASP ASN GLN ILE GLN          
SEQRES  16 I  440  GLU ILE LYS GLU SER VAL GLU LEU PRO LEU THR HIS PRO          
SEQRES  17 I  440  GLU TYR TYR GLU GLU MET GLY ILE LYS PRO PRO LYS GLY          
SEQRES  18 I  440  VAL ILE LEU TYR GLY PRO PRO GLY THR GLY LYS THR LEU          
SEQRES  19 I  440  LEU ALA LYS ALA VAL ALA ASN GLN THR SER ALA THR PHE          
SEQRES  20 I  440  LEU ARG VAL VAL GLY SER GLU LEU ILE GLN LYS TYR LEU          
SEQRES  21 I  440  GLY ASP GLY PRO LYS LEU VAL ARG GLU LEU PHE ARG VAL          
SEQRES  22 I  440  ALA GLU GLU HIS ALA PRO SER ILE VAL PHE ILE ASP GLU          
SEQRES  23 I  440  ILE ASP ALA ILE GLY THR LYS ARG TYR ASP SER ASN SER          
SEQRES  24 I  440  GLY GLY GLU ARG GLU ILE GLN ARG THR MET LEU GLU LEU          
SEQRES  25 I  440  LEU ASN GLN LEU ASP GLY PHE ASP SER ARG GLY ASP VAL          
SEQRES  26 I  440  LYS VAL ILE MET ALA THR ASN ARG ILE GLU THR LEU ASP          
SEQRES  27 I  440  PRO ALA LEU ILE ARG PRO GLY ARG ILE ASP ARG LYS ILE          
SEQRES  28 I  440  GLU PHE PRO LEU PRO ASP GLU LYS THR LYS LYS ARG ILE          
SEQRES  29 I  440  PHE GLN ILE HIS THR SER ARG MET THR LEU ALA ASP ASP          
SEQRES  30 I  440  VAL THR LEU ASP ASP LEU ILE MET ALA LYS ASP ASP LEU          
SEQRES  31 I  440  SER GLY ALA ASP ILE LYS ALA ILE CYS THR GLU ALA GLY          
SEQRES  32 I  440  LEU MET ALA LEU ARG GLU ARG ARG MET LYS VAL THR ASN          
SEQRES  33 I  440  GLU ASP PHE LYS LYS SER LYS GLU ASN VAL LEU TYR LYS          
SEQRES  34 I  440  LYS GLN GLU GLY THR PRO GLU GLY LEU TYR LEU                  
SEQRES   1 J  406  MET ALA LEU ASP GLY PRO GLU GLN MET GLU LEU GLU GLU          
SEQRES   2 J  406  GLY LYS ALA GLY SER GLY LEU ARG GLN TYR TYR LEU SER          
SEQRES   3 J  406  LYS ILE GLU GLU LEU GLN LEU ILE VAL ASN ASP LYS SER          
SEQRES   4 J  406  GLN ASN LEU ARG ARG LEU GLN ALA GLN ARG ASN GLU LEU          
SEQRES   5 J  406  ASN ALA LYS VAL ARG LEU LEU ARG GLU GLU LEU GLN LEU          
SEQRES   6 J  406  LEU GLN GLU GLN GLY SER TYR VAL GLY GLU VAL VAL ARG          
SEQRES   7 J  406  ALA MET ASP LYS LYS LYS VAL LEU VAL LYS VAL HIS PRO          
SEQRES   8 J  406  GLU GLY LYS PHE VAL VAL ASP VAL ASP LYS ASN ILE ASP          
SEQRES   9 J  406  ILE ASN ASP VAL THR PRO ASN CYS ARG VAL ALA LEU ARG          
SEQRES  10 J  406  ASN ASP SER TYR THR LEU HIS LYS ILE LEU PRO ASN LYS          
SEQRES  11 J  406  VAL ASP PRO LEU VAL SER LEU MET MET VAL GLU LYS VAL          
SEQRES  12 J  406  PRO ASP SER THR TYR GLU MET ILE GLY GLY LEU ASP LYS          
SEQRES  13 J  406  GLN ILE LYS GLU ILE LYS GLU VAL ILE GLU LEU PRO VAL          
SEQRES  14 J  406  LYS HIS PRO GLU LEU PHE GLU ALA LEU GLY ILE ALA GLN          
SEQRES  15 J  406  PRO LYS GLY VAL LEU LEU TYR GLY PRO PRO GLY THR GLY          
SEQRES  16 J  406  LYS THR LEU LEU ALA ARG ALA VAL ALA HIS HIS THR ASP          
SEQRES  17 J  406  CYS THR PHE ILE ARG VAL SER GLY SER GLU LEU VAL GLN          
SEQRES  18 J  406  LYS PHE ILE GLY GLU GLY ALA ARG MET VAL ARG GLU LEU          
SEQRES  19 J  406  PHE VAL MET ALA ARG GLU HIS ALA PRO SER ILE ILE PHE          
SEQRES  20 J  406  MET ASP GLU ILE ASP SER ILE GLY SER SER ARG LEU GLU          
SEQRES  21 J  406  GLY GLY SER GLY GLY ASP SER GLU VAL GLN ARG THR MET          
SEQRES  22 J  406  LEU GLU LEU LEU ASN GLN LEU ASP GLY PHE GLU ALA THR          
SEQRES  23 J  406  LYS ASN ILE LYS VAL ILE MET ALA THR ASN ARG ILE ASP          
SEQRES  24 J  406  ILE LEU ASP SER ALA LEU LEU ARG PRO GLY ARG ILE ASP          
SEQRES  25 J  406  ARG LYS ILE GLU PHE PRO PRO PRO ASN GLU GLU ALA ARG          
SEQRES  26 J  406  LEU ASP ILE LEU LYS ILE HIS SER ARG LYS MET ASN LEU          
SEQRES  27 J  406  THR ARG GLY ILE ASN LEU ARG LYS ILE ALA GLU LEU MET          
SEQRES  28 J  406  PRO GLY ALA SER GLY ALA GLU VAL LYS GLY VAL CYS THR          
SEQRES  29 J  406  GLU ALA GLY MET TYR ALA LEU ARG GLU ARG ARG VAL HIS          
SEQRES  30 J  406  VAL THR GLN GLU ASP PHE GLU MET ALA VAL ALA LYS VAL          
SEQRES  31 J  406  MET GLN LYS ASP SER GLU LYS ASN MET SER ILE LYS LYS          
SEQRES  32 J  406  LEU TRP LYS                                                  
SEQRES   1 K  418  MET GLU GLU ILE GLY ILE LEU VAL GLU LYS ALA GLN ASP          
SEQRES   2 K  418  GLU ILE PRO ALA LEU SER VAL SER ARG PRO GLN THR GLY          
SEQRES   3 K  418  LEU SER PHE LEU GLY PRO GLU PRO GLU ASP LEU GLU ASP          
SEQRES   4 K  418  LEU TYR SER ARG TYR LYS LYS LEU GLN GLN GLU LEU GLU          
SEQRES   5 K  418  PHE LEU GLU VAL GLN GLU GLU TYR ILE LYS ASP GLU GLN          
SEQRES   6 K  418  LYS ASN LEU LYS LYS GLU PHE LEU HIS ALA GLN GLU GLU          
SEQRES   7 K  418  VAL LYS ARG ILE GLN SER ILE PRO LEU VAL ILE GLY GLN          
SEQRES   8 K  418  PHE LEU GLU ALA VAL ASP GLN ASN THR ALA ILE VAL GLY          
SEQRES   9 K  418  SER THR THR GLY SER ASN TYR TYR VAL ARG ILE LEU SER          
SEQRES  10 K  418  THR ILE ASP ARG GLU LEU LEU LYS PRO ASN ALA SER VAL          
SEQRES  11 K  418  ALA LEU HIS LYS HIS SER ASN ALA LEU VAL ASP VAL LEU          
SEQRES  12 K  418  PRO PRO GLU ALA ASP SER SER ILE MET MET LEU THR SER          
SEQRES  13 K  418  ASP GLN LYS PRO ASP VAL MET TYR ALA ASP ILE GLY GLY          
SEQRES  14 K  418  MET ASP ILE GLN LYS GLN GLU VAL ARG GLU ALA VAL GLU          
SEQRES  15 K  418  LEU PRO LEU THR HIS PHE GLU LEU TYR LYS GLN ILE GLY          
SEQRES  16 K  418  ILE ASP PRO PRO ARG GLY VAL LEU MET TYR GLY PRO PRO          
SEQRES  17 K  418  GLY CYS GLY LYS THR MET LEU ALA LYS ALA VAL ALA HIS          
SEQRES  18 K  418  HIS THR THR ALA ALA PHE ILE ARG VAL VAL GLY SER GLU          
SEQRES  19 K  418  PHE VAL GLN LYS TYR LEU GLY GLU GLY PRO ARG MET VAL          
SEQRES  20 K  418  ARG ASP VAL PHE ARG LEU ALA LYS GLU ASN ALA PRO ALA          
SEQRES  21 K  418  ILE ILE PHE ILE ASP GLU ILE ASP ALA ILE ALA THR LYS          
SEQRES  22 K  418  ARG PHE ASP ALA GLN THR GLY ALA ASP ARG GLU VAL GLN          
SEQRES  23 K  418  ARG ILE LEU LEU GLU LEU LEU ASN GLN MET ASP GLY PHE          
SEQRES  24 K  418  ASP GLN ASN VAL ASN VAL LYS VAL ILE MET ALA THR ASN          
SEQRES  25 K  418  ARG ALA ASP THR LEU ASP PRO ALA LEU LEU ARG PRO GLY          
SEQRES  26 K  418  ARG LEU ASP ARG LYS ILE GLU PHE PRO LEU PRO ASP ARG          
SEQRES  27 K  418  ARG GLN LYS ARG LEU ILE PHE SER THR ILE THR SER LYS          
SEQRES  28 K  418  MET ASN LEU SER GLU GLU VAL ASP LEU GLU ASP TYR VAL          
SEQRES  29 K  418  ALA ARG PRO ASP LYS ILE SER GLY ALA ASP ILE ASN SER          
SEQRES  30 K  418  ILE CYS GLN GLU SER GLY MET LEU ALA VAL ARG GLU ASN          
SEQRES  31 K  418  ARG TYR ILE VAL LEU ALA LYS ASP PHE GLU LYS ALA TYR          
SEQRES  32 K  418  LYS THR VAL ILE LYS LYS ASP GLU GLN GLU HIS GLU PHE          
SEQRES  33 K  418  TYR LYS                                                      
SEQRES   1 L  389  MET ALA ASP PRO ARG ASP LYS ALA LEU GLN ASP TYR ARG          
SEQRES   2 L  389  LYS LYS LEU LEU GLU HIS LYS GLU ILE ASP GLY ARG LEU          
SEQRES   3 L  389  LYS GLU LEU ARG GLU GLN LEU LYS GLU LEU THR LYS GLN          
SEQRES   4 L  389  TYR GLU LYS SER GLU ASN ASP LEU LYS ALA LEU GLN SER          
SEQRES   5 L  389  VAL GLY GLN ILE VAL GLY GLU VAL LEU LYS GLN LEU THR          
SEQRES   6 L  389  GLU GLU LYS PHE ILE VAL LYS ALA THR ASN GLY PRO ARG          
SEQRES   7 L  389  TYR VAL VAL GLY CYS ARG ARG GLN LEU ASP LYS SER LYS          
SEQRES   8 L  389  LEU LYS PRO GLY THR ARG VAL ALA LEU ASP MET THR THR          
SEQRES   9 L  389  LEU THR ILE MET ARG TYR LEU PRO ARG GLU VAL ASP PRO          
SEQRES  10 L  389  LEU VAL TYR ASN MET SER HIS GLU ASP PRO GLY ASN VAL          
SEQRES  11 L  389  SER TYR SER GLU ILE GLY GLY LEU SER GLU GLN ILE ARG          
SEQRES  12 L  389  GLU LEU ARG GLU VAL ILE GLU LEU PRO LEU THR ASN PRO          
SEQRES  13 L  389  GLU LEU PHE GLN ARG VAL GLY ILE ILE PRO PRO LYS GLY          
SEQRES  14 L  389  CYS LEU LEU TYR GLY PRO PRO GLY THR GLY LYS THR LEU          
SEQRES  15 L  389  LEU ALA ARG ALA VAL ALA SER GLN LEU ASP CYS ASN PHE          
SEQRES  16 L  389  LEU LYS VAL VAL SER SER SER ILE VAL ASP LYS TYR ILE          
SEQRES  17 L  389  GLY GLU SER ALA ARG LEU ILE ARG GLU MET PHE ASN TYR          
SEQRES  18 L  389  ALA ARG ASP HIS GLN PRO CYS ILE ILE PHE MET ASP GLU          
SEQRES  19 L  389  ILE ASP ALA ILE GLY GLY ARG ARG PHE SER GLU GLY THR          
SEQRES  20 L  389  SER ALA ASP ARG GLU ILE GLN ARG THR LEU MET GLU LEU          
SEQRES  21 L  389  LEU ASN GLN MET ASP GLY PHE ASP THR LEU HIS ARG VAL          
SEQRES  22 L  389  LYS MET ILE MET ALA THR ASN ARG PRO ASP THR LEU ASP          
SEQRES  23 L  389  PRO ALA LEU LEU ARG PRO GLY ARG LEU ASP ARG LYS ILE          
SEQRES  24 L  389  HIS ILE ASP LEU PRO ASN GLU GLN ALA ARG LEU ASP ILE          
SEQRES  25 L  389  LEU LYS ILE HIS ALA GLY PRO ILE THR LYS HIS GLY GLU          
SEQRES  26 L  389  ILE ASP TYR GLU ALA ILE VAL LYS LEU SER ASP GLY PHE          
SEQRES  27 L  389  ASN GLY ALA ASP LEU ARG ASN VAL CYS THR GLU ALA GLY          
SEQRES  28 L  389  MET PHE ALA ILE ARG ALA ASP HIS ASP PHE VAL VAL GLN          
SEQRES  29 L  389  GLU ASP PHE MET LYS ALA VAL ARG LYS VAL ALA ASP SER          
SEQRES  30 L  389  LYS LYS LEU GLU SER LYS LEU ASP TYR LYS PRO VAL              
SEQRES   1 M  439  MET ASN LEU LEU PRO ASN ILE GLU SER PRO VAL THR ARG          
SEQRES   2 M  439  GLN GLU LYS MET ALA THR VAL TRP ASP GLU ALA GLU GLN          
SEQRES   3 M  439  ASP GLY ILE GLY GLU GLU VAL LEU LYS MET SER THR GLU          
SEQRES   4 M  439  GLU ILE ILE GLN ARG THR ARG LEU LEU ASP SER GLU ILE          
SEQRES   5 M  439  LYS ILE MET LYS SER GLU VAL LEU ARG VAL THR HIS GLU          
SEQRES   6 M  439  LEU GLN ALA MET LYS ASP LYS ILE LYS GLU ASN SER GLU          
SEQRES   7 M  439  LYS ILE LYS VAL ASN LYS THR LEU PRO TYR LEU VAL SER          
SEQRES   8 M  439  ASN VAL ILE GLU LEU LEU ASP VAL ASP PRO ASN ASP GLN          
SEQRES   9 M  439  GLU GLU ASP GLY ALA ASN ILE ASP LEU ASP SER GLN ARG          
SEQRES  10 M  439  LYS GLY LYS CYS ALA VAL ILE LYS THR SER THR ARG GLN          
SEQRES  11 M  439  THR TYR PHE LEU PRO VAL ILE GLY LEU VAL ASP ALA GLU          
SEQRES  12 M  439  LYS LEU LYS PRO GLY ASP LEU VAL GLY VAL ASN LYS ASP          
SEQRES  13 M  439  SER TYR LEU ILE LEU GLU THR LEU PRO THR GLU TYR ASP          
SEQRES  14 M  439  SER ARG VAL LYS ALA MET GLU VAL ASP GLU ARG PRO THR          
SEQRES  15 M  439  GLU GLN TYR SER ASP ILE GLY GLY LEU ASP LYS GLN ILE          
SEQRES  16 M  439  GLN GLU LEU VAL GLU ALA ILE VAL LEU PRO MET ASN HIS          
SEQRES  17 M  439  LYS GLU LYS PHE GLU ASN LEU GLY ILE GLN PRO PRO LYS          
SEQRES  18 M  439  GLY VAL LEU MET TYR GLY PRO PRO GLY THR GLY LYS THR          
SEQRES  19 M  439  LEU LEU ALA ARG ALA CYS ALA ALA GLN THR LYS ALA THR          
SEQRES  20 M  439  PHE LEU LYS LEU ALA GLY PRO GLN LEU VAL GLN MET PHE          
SEQRES  21 M  439  ILE GLY ASP GLY ALA LYS LEU VAL ARG ASP ALA PHE ALA          
SEQRES  22 M  439  LEU ALA LYS GLU LYS ALA PRO SER ILE ILE PHE ILE ASP          
SEQRES  23 M  439  GLU LEU ASP ALA ILE GLY THR LYS ARG PHE ASP SER GLU          
SEQRES  24 M  439  LYS ALA GLY ASP ARG GLU VAL GLN ARG THR MET LEU GLU          
SEQRES  25 M  439  LEU LEU ASN GLN LEU ASP GLY PHE GLN PRO ASN THR GLN          
SEQRES  26 M  439  VAL LYS VAL ILE ALA ALA THR ASN ARG VAL ASP ILE LEU          
SEQRES  27 M  439  ASP PRO ALA LEU LEU ARG SER GLY ARG LEU ASP ARG LYS          
SEQRES  28 M  439  ILE GLU PHE PRO MET PRO ASN GLU GLU ALA ARG ALA ARG          
SEQRES  29 M  439  ILE MET GLN ILE HIS SER ARG LYS MET ASN VAL SER PRO          
SEQRES  30 M  439  ASP VAL ASN TYR GLU GLU LEU ALA ARG CYS THR ASP ASP          
SEQRES  31 M  439  PHE ASN GLY ALA GLN CYS LYS ALA VAL CYS VAL GLU ALA          
SEQRES  32 M  439  GLY MET ILE ALA LEU ARG ARG GLY ALA THR GLU LEU THR          
SEQRES  33 M  439  HIS GLU ASP TYR MET GLU GLY ILE LEU GLU VAL GLN ALA          
SEQRES  34 M  439  LYS LYS LYS ALA ASN LEU GLN TYR TYR ALA                      
SEQRES   1 N  953  MET ILE THR SER ALA ALA GLY ILE ILE SER LEU LEU ASP          
SEQRES   2 N  953  GLU ASP GLU PRO GLN LEU LYS GLU PHE ALA LEU HIS LYS          
SEQRES   3 N  953  LEU ASN ALA VAL VAL ASN ASP PHE TRP ALA GLU ILE SER          
SEQRES   4 N  953  GLU SER VAL ASP LYS ILE GLU VAL LEU TYR GLU ASP GLU          
SEQRES   5 N  953  GLY PHE ARG SER ARG GLN PHE ALA ALA LEU VAL ALA SER          
SEQRES   6 N  953  LYS VAL PHE TYR HIS LEU GLY ALA PHE GLU GLU SER LEU          
SEQRES   7 N  953  ASN TYR ALA LEU GLY ALA GLY ASP LEU PHE ASN VAL ASN          
SEQRES   8 N  953  ASP ASN SER GLU TYR VAL GLU THR ILE ILE ALA LYS CYS          
SEQRES   9 N  953  ILE ASP HIS TYR THR LYS GLN CYS VAL GLU ASN ALA ASP          
SEQRES  10 N  953  LEU PRO GLU GLY GLU LYS LYS PRO ILE ASP GLN ARG LEU          
SEQRES  11 N  953  GLU GLY ILE VAL ASN LYS MET PHE GLN ARG CYS LEU ASP          
SEQRES  12 N  953  ASP HIS LYS TYR LYS GLN ALA ILE GLY ILE ALA LEU GLU          
SEQRES  13 N  953  THR ARG ARG LEU ASP VAL PHE GLU LYS THR ILE LEU GLU          
SEQRES  14 N  953  SER ASN ASP VAL PRO GLY MET LEU ALA TYR SER LEU LYS          
SEQRES  15 N  953  LEU CYS MET SER LEU MET GLN ASN LYS GLN PHE ARG ASN          
SEQRES  16 N  953  LYS VAL LEU ARG VAL LEU VAL LYS ILE TYR MET ASN LEU          
SEQRES  17 N  953  GLU LYS PRO ASP PHE ILE ASN VAL CYS GLN CYS LEU ILE          
SEQRES  18 N  953  PHE LEU ASP ASP PRO GLN ALA VAL SER ASP ILE LEU GLU          
SEQRES  19 N  953  LYS LEU VAL LYS GLU ASP ASN LEU LEU MET ALA TYR GLN          
SEQRES  20 N  953  ILE CYS PHE ASP LEU TYR GLU SER ALA SER GLN GLN PHE          
SEQRES  21 N  953  LEU SER SER VAL ILE GLN ASN LEU ARG THR VAL GLY THR          
SEQRES  22 N  953  PRO ILE ALA SER VAL PRO GLY SER THR ASN THR GLY THR          
SEQRES  23 N  953  VAL PRO GLY SER GLU LYS ASP SER ASP SER MET GLU THR          
SEQRES  24 N  953  GLU GLU LYS THR SER SER ALA PHE VAL GLY LYS THR PRO          
SEQRES  25 N  953  GLU ALA SER PRO GLU PRO LYS ASP GLN THR LEU LYS MET          
SEQRES  26 N  953  ILE LYS ILE LEU SER GLY GLU MET ALA ILE GLU LEU HIS          
SEQRES  27 N  953  LEU GLN PHE LEU ILE ARG ASN ASN ASN THR ASP LEU MET          
SEQRES  28 N  953  ILE LEU LYS ASN THR LYS ASP ALA VAL ARG ASN SER VAL          
SEQRES  29 N  953  CYS HIS THR ALA THR VAL ILE ALA ASN SER PHE MET HIS          
SEQRES  30 N  953  CYS GLY THR THR SER ASP GLN PHE LEU ARG ASP ASN LEU          
SEQRES  31 N  953  GLU TRP LEU ALA ARG ALA THR ASN TRP ALA LYS PHE THR          
SEQRES  32 N  953  ALA THR ALA SER LEU GLY VAL ILE HIS LYS GLY HIS GLU          
SEQRES  33 N  953  LYS GLU ALA LEU GLN LEU MET ALA THR TYR LEU PRO LYS          
SEQRES  34 N  953  ASP THR SER PRO GLY SER ALA TYR GLN GLU GLY GLY GLY          
SEQRES  35 N  953  LEU TYR ALA LEU GLY LEU ILE HIS ALA ASN HIS GLY GLY          
SEQRES  36 N  953  ASP ILE ILE ASP TYR LEU LEU ASN GLN LEU LYS ASN ALA          
SEQRES  37 N  953  SER ASN ASP ILE VAL ARG HIS GLY GLY SER LEU GLY LEU          
SEQRES  38 N  953  GLY LEU ALA ALA MET GLY THR ALA ARG GLN ASP VAL TYR          
SEQRES  39 N  953  ASP LEU LEU LYS THR ASN LEU TYR GLN ASP ASP ALA VAL          
SEQRES  40 N  953  THR GLY GLU ALA ALA GLY LEU ALA LEU GLY LEU VAL MET          
SEQRES  41 N  953  LEU GLY SER LYS ASN ALA GLN ALA ILE GLU ASP MET VAL          
SEQRES  42 N  953  GLY TYR ALA GLN GLU THR GLN HIS GLU LYS ILE LEU ARG          
SEQRES  43 N  953  GLY LEU ALA VAL GLY ILE ALA LEU VAL MET TYR GLY ARG          
SEQRES  44 N  953  MET GLU GLU ALA ASP ALA LEU ILE GLU SER LEU CYS ARG          
SEQRES  45 N  953  ASP LYS ASP PRO ILE LEU ARG ARG SER GLY MET TYR THR          
SEQRES  46 N  953  VAL ALA MET ALA TYR CYS GLY SER GLY ASN ASN LYS ALA          
SEQRES  47 N  953  ILE ARG ARG LEU LEU HIS VAL ALA VAL SER ASP VAL ASN          
SEQRES  48 N  953  ASP ASP VAL ARG ARG ALA ALA VAL GLU SER LEU GLY PHE          
SEQRES  49 N  953  ILE LEU PHE ARG THR PRO GLU GLN CYS PRO SER VAL VAL          
SEQRES  50 N  953  SER LEU LEU SER GLU SER TYR ASN PRO HIS VAL ARG TYR          
SEQRES  51 N  953  GLY ALA ALA MET ALA LEU GLY ILE CYS CYS ALA GLY THR          
SEQRES  52 N  953  GLY ASN LYS GLU ALA ILE ASN LEU LEU GLU PRO MET THR          
SEQRES  53 N  953  ASN ASP PRO VAL ASN TYR VAL ARG GLN GLY ALA LEU ILE          
SEQRES  54 N  953  ALA SER ALA LEU ILE MET ILE GLN GLN THR GLU ILE THR          
SEQRES  55 N  953  CYS PRO LYS VAL ASN GLN PHE ARG GLN LEU TYR SER LYS          
SEQRES  56 N  953  VAL ILE ASN ASP LYS HIS ASP ASP VAL MET ALA LYS PHE          
SEQRES  57 N  953  GLY ALA ILE LEU ALA GLN GLY ILE LEU ASP ALA GLY GLY          
SEQRES  58 N  953  HIS ASN VAL THR ILE SER LEU GLN SER ARG THR GLY HIS          
SEQRES  59 N  953  THR HIS MET PRO SER VAL VAL GLY VAL LEU VAL PHE THR          
SEQRES  60 N  953  GLN PHE TRP PHE TRP PHE PRO LEU SER HIS PHE LEU SER          
SEQRES  61 N  953  LEU ALA TYR THR PRO THR CYS VAL ILE GLY LEU ASN LYS          
SEQRES  62 N  953  ASP LEU LYS MET PRO LYS VAL GLN TYR LYS SER ASN CYS          
SEQRES  63 N  953  LYS PRO SER THR PHE ALA TYR PRO ALA PRO LEU GLU VAL          
SEQRES  64 N  953  PRO LYS GLU LYS GLU LYS GLU LYS VAL SER THR ALA VAL          
SEQRES  65 N  953  LEU SER ILE THR ALA LYS ALA LYS LYS LYS GLU LYS GLU          
SEQRES  66 N  953  LYS GLU LYS LYS GLU GLU GLU LYS MET GLU VAL ASP GLU          
SEQRES  67 N  953  ALA GLU LYS LYS GLU GLU LYS GLU LYS LYS LYS GLU PRO          
SEQRES  68 N  953  GLU PRO ASN PHE GLN LEU LEU ASP ASN PRO ALA ARG VAL          
SEQRES  69 N  953  MET PRO ALA GLN LEU LYS VAL LEU THR MET PRO GLU THR          
SEQRES  70 N  953  CYS ARG TYR GLN PRO PHE LYS PRO LEU SER ILE GLY GLY          
SEQRES  71 N  953  ILE ILE ILE LEU LYS ASP THR SER GLU ASP ILE GLU GLU          
SEQRES  72 N  953  LEU VAL GLU PRO VAL ALA ALA HIS GLY PRO LYS ILE GLU          
SEQRES  73 N  953  GLU GLU GLU GLN GLU PRO GLU PRO PRO GLU PRO PHE GLU          
SEQRES  74 N  953  TYR ILE ASP ASP                                              
SEQRES   1 O  376  MET LYS ASP VAL PRO GLY PHE LEU GLN GLN SER GLN ASN          
SEQRES   2 O  376  SER GLY PRO GLY GLN PRO ALA VAL TRP HIS ARG LEU GLU          
SEQRES   3 O  376  GLU LEU TYR THR LYS LYS LEU TRP HIS GLN LEU THR LEU          
SEQRES   4 O  376  GLN VAL LEU ASP PHE VAL GLN ASP PRO CYS PHE ALA GLN          
SEQRES   5 O  376  GLY ASP GLY LEU ILE LYS LEU TYR GLU ASN PHE ILE SER          
SEQRES   6 O  376  GLU PHE GLU HIS ARG VAL ASN PRO LEU SER LEU VAL GLU          
SEQRES   7 O  376  ILE ILE LEU HIS VAL VAL ARG GLN MET THR ASP PRO ASN          
SEQRES   8 O  376  VAL ALA LEU THR PHE LEU GLU LYS THR ARG GLU LYS VAL          
SEQRES   9 O  376  LYS SER SER ASP GLU ALA VAL ILE LEU CYS LYS THR ALA          
SEQRES  10 O  376  ILE GLY ALA LEU LYS LEU ASN ILE GLY ASP LEU GLN VAL          
SEQRES  11 O  376  THR LYS GLU THR ILE GLU ASP VAL GLU GLU MET LEU ASN          
SEQRES  12 O  376  ASN LEU PRO GLY VAL THR SER VAL HIS SER ARG PHE TYR          
SEQRES  13 O  376  ASP LEU SER SER LYS TYR TYR GLN THR ILE GLY ASN HIS          
SEQRES  14 O  376  ALA SER TYR TYR LYS ASP ALA LEU ARG PHE LEU GLY CYS          
SEQRES  15 O  376  VAL ASP ILE LYS ASP LEU PRO VAL SER GLU GLN GLN GLU          
SEQRES  16 O  376  ARG ALA PHE THR LEU GLY LEU ALA GLY LEU LEU GLY GLU          
SEQRES  17 O  376  GLY VAL PHE ASN PHE GLY GLU LEU LEU MET HIS PRO VAL          
SEQRES  18 O  376  LEU GLU SER LEU ARG ASN THR ASP ARG GLN TRP LEU ILE          
SEQRES  19 O  376  ASP THR LEU TYR ALA PHE ASN SER GLY ASN VAL GLU ARG          
SEQRES  20 O  376  PHE GLN THR LEU LYS THR ALA TRP GLY GLN GLN PRO ASP          
SEQRES  21 O  376  LEU ALA ALA ASN GLU ALA GLN LEU LEU ARG LYS ILE GLN          
SEQRES  22 O  376  LEU LEU CYS LEU MET GLU MET THR PHE THR ARG PRO ALA          
SEQRES  23 O  376  ASN HIS ARG GLN LEU THR PHE GLU GLU ILE ALA LYS SER          
SEQRES  24 O  376  ALA LYS ILE THR VAL ASN GLU VAL GLU LEU LEU VAL MET          
SEQRES  25 O  376  LYS ALA LEU SER VAL GLY LEU VAL LYS GLY SER ILE ASP          
SEQRES  26 O  376  GLU VAL ASP LYS ARG VAL HIS MET THR TRP VAL GLN PRO          
SEQRES  27 O  376  ARG VAL LEU ASP LEU GLN GLN ILE LYS GLY MET LYS ASP          
SEQRES  28 O  376  ARG LEU GLU PHE TRP CYS THR ASP VAL LYS SER MET GLU          
SEQRES  29 O  376  MET LEU VAL GLU HIS GLN ALA HIS ASP ILE LEU THR              
SEQRES   1 P  456  MET ALA ASP GLY GLY SER GLU ARG ALA ASP GLY ARG ILE          
SEQRES   2 P  456  VAL LYS MET GLU VAL ASP TYR SER ALA THR VAL ASP GLN          
SEQRES   3 P  456  ARG LEU PRO GLU CYS ALA LYS LEU ALA LYS GLU GLY ARG          
SEQRES   4 P  456  LEU GLN GLU VAL ILE GLU THR LEU LEU SER LEU GLU LYS          
SEQRES   5 P  456  GLN THR ARG THR ALA SER ASP MET VAL SER THR SER ARG          
SEQRES   6 P  456  ILE LEU VAL ALA VAL VAL LYS MET CYS TYR GLU ALA LYS          
SEQRES   7 P  456  GLU TRP ASP LEU LEU ASN GLU ASN ILE MET LEU LEU SER          
SEQRES   8 P  456  LYS ARG ARG SER GLN LEU LYS GLN ALA VAL ALA LYS MET          
SEQRES   9 P  456  VAL GLN GLN CYS CYS THR TYR VAL GLU GLU ILE THR ASP          
SEQRES  10 P  456  LEU PRO ILE LYS LEU ARG LEU ILE ASP THR LEU ARG MET          
SEQRES  11 P  456  VAL THR GLU GLY LYS ILE TYR VAL GLU ILE GLU ARG ALA          
SEQRES  12 P  456  ARG LEU THR LYS THR LEU ALA THR ILE LYS GLU GLN ASN          
SEQRES  13 P  456  GLY ASP VAL LYS GLU ALA ALA SER ILE LEU GLN GLU LEU          
SEQRES  14 P  456  GLN VAL GLU THR TYR GLY SER MET GLU LYS LYS GLU ARG          
SEQRES  15 P  456  VAL GLU PHE ILE LEU GLU GLN MET ARG LEU CYS LEU ALA          
SEQRES  16 P  456  VAL LYS ASP TYR ILE ARG THR GLN ILE ILE SER LYS LYS          
SEQRES  17 P  456  ILE ASN THR LYS PHE PHE GLN GLU GLU ASN THR GLU LYS          
SEQRES  18 P  456  LEU LYS LEU LYS TYR TYR ASN LEU MET ILE GLN LEU ASP          
SEQRES  19 P  456  GLN HIS GLU GLY SER TYR LEU SER ILE CYS LYS HIS TYR          
SEQRES  20 P  456  ARG ALA ILE TYR ASP THR PRO CYS ILE GLN ALA GLU SER          
SEQRES  21 P  456  GLU LYS TRP GLN GLN ALA LEU LYS SER VAL VAL LEU TYR          
SEQRES  22 P  456  VAL ILE LEU ALA PRO PHE ASP ASN GLU GLN SER ASP LEU          
SEQRES  23 P  456  VAL HIS ARG ILE SER GLY ASP LYS LYS LEU GLU GLU ILE          
SEQRES  24 P  456  PRO LYS TYR LYS ASP LEU LEU LYS LEU PHE THR THR MET          
SEQRES  25 P  456  GLU LEU MET ARG TRP SER THR LEU VAL GLU ASP TYR GLY          
SEQRES  26 P  456  MET GLU LEU ARG LYS GLY SER LEU GLU SER PRO ALA THR          
SEQRES  27 P  456  ASP VAL PHE GLY SER THR GLU GLU GLY GLU LYS ARG TRP          
SEQRES  28 P  456  LYS ASP LEU LYS ASN ARG VAL VAL GLU HIS ASN ILE ARG          
SEQRES  29 P  456  ILE MET ALA LYS TYR TYR THR ARG ILE THR MET LYS ARG          
SEQRES  30 P  456  MET ALA GLN LEU LEU ASP LEU SER VAL ASP GLU SER GLU          
SEQRES  31 P  456  ALA PHE LEU SER ASN LEU VAL VAL ASN LYS THR ILE PHE          
SEQRES  32 P  456  ALA LYS VAL ASP ARG LEU ALA GLY ILE ILE ASN PHE GLN          
SEQRES  33 P  456  ARG PRO LYS ASP PRO ASN ASN LEU LEU ASN ASP TRP SER          
SEQRES  34 P  456  GLN LYS LEU ASN SER LEU MET SER LEU VAL ASN LYS THR          
SEQRES  35 P  456  THR HIS LEU ILE ALA LYS GLU GLU MET ILE HIS ASN LEU          
SEQRES  36 P  456  GLN                                                          
SEQRES   1 Q  422  MET ALA ALA ALA ALA VAL VAL GLU PHE GLN ARG ALA GLN          
SEQRES   2 Q  422  SER LEU LEU SER THR ASP ARG GLU ALA SER ILE ASP ILE          
SEQRES   3 Q  422  LEU HIS SER ILE VAL LYS ARG ASP ILE GLN GLU ASN ASP          
SEQRES   4 Q  422  GLU GLU ALA VAL GLN VAL LYS GLU GLN SER ILE LEU GLU          
SEQRES   5 Q  422  LEU GLY SER LEU LEU ALA LYS THR GLY GLN ALA ALA GLU          
SEQRES   6 Q  422  LEU GLY GLY LEU LEU LYS TYR VAL ARG PRO PHE LEU ASN          
SEQRES   7 Q  422  SER ILE SER LYS ALA LYS ALA ALA ARG LEU VAL ARG SER          
SEQRES   8 Q  422  LEU LEU ASP LEU PHE LEU ASP MET GLU ALA ALA THR GLY          
SEQRES   9 Q  422  GLN GLU VAL GLU LEU CYS LEU GLU CYS ILE GLU TRP ALA          
SEQRES  10 Q  422  LYS SER GLU LYS ARG THR PHE LEU ARG GLN ALA LEU GLU          
SEQRES  11 Q  422  ALA ARG LEU VAL SER LEU TYR PHE ASP THR LYS ARG TYR          
SEQRES  12 Q  422  GLN GLU ALA LEU HIS LEU GLY SER GLN LEU LEU ARG GLU          
SEQRES  13 Q  422  LEU LYS LYS MET ASP ASP LYS ALA LEU LEU VAL GLU VAL          
SEQRES  14 Q  422  GLN LEU LEU GLU SER LYS THR TYR HIS ALA LEU SER ASN          
SEQRES  15 Q  422  LEU PRO LYS ALA ARG ALA ALA LEU THR SER ALA ARG THR          
SEQRES  16 Q  422  THR ALA ASN ALA ILE TYR CYS PRO PRO LYS LEU GLN ALA          
SEQRES  17 Q  422  THR LEU ASP MET GLN SER GLY ILE ILE HIS ALA ALA GLU          
SEQRES  18 Q  422  GLU LYS ASP TRP LYS THR ALA TYR SER TYR PHE TYR GLU          
SEQRES  19 Q  422  ALA PHE GLU GLY TYR ASP SER ILE ASP SER PRO LYS ALA          
SEQRES  20 Q  422  ILE THR SER LEU LYS TYR MET LEU LEU CYS LYS ILE MET          
SEQRES  21 Q  422  LEU ASN THR PRO GLU ASP VAL GLN ALA LEU VAL SER GLY          
SEQRES  22 Q  422  LYS LEU ALA LEU ARG TYR ALA GLY ARG GLN THR GLU ALA          
SEQRES  23 Q  422  LEU LYS CYS VAL ALA GLN ALA SER LYS ASN ARG SER LEU          
SEQRES  24 Q  422  ALA ASP PHE GLU LYS ALA LEU THR ASP TYR ARG ALA GLU          
SEQRES  25 Q  422  LEU ARG ASP ASP PRO ILE ILE SER THR HIS LEU ALA LYS          
SEQRES  26 Q  422  LEU TYR ASP ASN LEU LEU GLU GLN ASN LEU ILE ARG VAL          
SEQRES  27 Q  422  ILE GLU PRO PHE SER ARG VAL GLN ILE GLU HIS ILE SER          
SEQRES  28 Q  422  SER LEU ILE LYS LEU SER LYS ALA ASP VAL GLU ARG LYS          
SEQRES  29 Q  422  LEU SER GLN MET ILE LEU ASP LYS LYS PHE HIS GLY ILE          
SEQRES  30 Q  422  LEU ASP GLN GLY GLU GLY VAL LEU ILE ILE PHE ASP GLU          
SEQRES  31 Q  422  PRO PRO VAL ASP LYS THR TYR GLU ALA ALA LEU GLU THR          
SEQRES  32 Q  422  ILE GLN ASN MET SER LYS VAL VAL ASP SER LEU TYR ASN          
SEQRES  33 Q  422  LYS ALA LYS LYS LEU THR                                      
SEQRES   1 R  389  MET PRO LEU GLU ASN LEU GLU GLU GLU GLY LEU PRO LYS          
SEQRES   2 R  389  ASN PRO ASP LEU ARG ILE ALA GLN LEU ARG PHE LEU LEU          
SEQRES   3 R  389  SER LEU PRO GLU HIS ARG GLY ASP ALA ALA VAL ARG ASP          
SEQRES   4 R  389  GLU LEU MET ALA ALA VAL ARG ASP ASN ASN MET ALA PRO          
SEQRES   5 R  389  TYR TYR GLU ALA LEU CYS LYS SER LEU ASP TRP GLN ILE          
SEQRES   6 R  389  ASP VAL ASP LEU LEU ASN LYS MET LYS LYS ALA ASN GLU          
SEQRES   7 R  389  ASP GLU LEU LYS ARG LEU ASP GLU GLU LEU GLU ASP ALA          
SEQRES   8 R  389  GLU LYS ASN LEU GLY GLU SER GLU ILE ARG ASP ALA MET          
SEQRES   9 R  389  MET ALA LYS ALA GLU TYR LEU CYS ARG ILE GLY ASP LYS          
SEQRES  10 R  389  GLU GLY ALA LEU THR ALA PHE ARG LYS THR TYR ASP LYS          
SEQRES  11 R  389  THR VAL ALA LEU GLY HIS ARG LEU ASP ILE VAL PHE TYR          
SEQRES  12 R  389  LEU LEU ARG ILE GLY LEU PHE TYR MET ASP ASN ASP LEU          
SEQRES  13 R  389  ILE THR ARG ASN THR GLU LYS ALA LYS SER LEU ILE GLU          
SEQRES  14 R  389  GLU GLY GLY ASP TRP ASP ARG ARG ASN ARG LEU LYS VAL          
SEQRES  15 R  389  TYR GLN GLY LEU TYR CYS VAL ALA ILE ARG ASP PHE LYS          
SEQRES  16 R  389  GLN ALA ALA GLU LEU PHE LEU ASP THR VAL SER THR PHE          
SEQRES  17 R  389  THR SER TYR GLU LEU MET ASP TYR LYS THR PHE VAL THR          
SEQRES  18 R  389  TYR THR VAL TYR VAL SER MET ILE ALA LEU GLU ARG PRO          
SEQRES  19 R  389  ASP LEU ARG GLU LYS VAL ILE LYS GLY ALA GLU ILE LEU          
SEQRES  20 R  389  GLU VAL LEU HIS SER LEU PRO ALA VAL ARG GLN TYR LEU          
SEQRES  21 R  389  PHE SER LEU TYR GLU CYS ARG TYR SER VAL PHE PHE GLN          
SEQRES  22 R  389  SER LEU ALA VAL VAL GLU GLN GLU MET LYS LYS ASP TRP          
SEQRES  23 R  389  LEU PHE ALA PRO HIS TYR ARG TYR TYR VAL ARG GLU MET          
SEQRES  24 R  389  ARG ILE HIS ALA TYR SER GLN LEU LEU GLU SER TYR ARG          
SEQRES  25 R  389  SER LEU THR LEU GLY TYR MET ALA GLU ALA PHE GLY VAL          
SEQRES  26 R  389  GLY VAL GLU PHE ILE ASP GLN GLU LEU SER ARG PHE ILE          
SEQRES  27 R  389  ALA ALA GLY ARG LEU HIS CYS LYS ILE ASP LYS VAL ASN          
SEQRES  28 R  389  GLU ILE VAL GLU THR ASN ARG PRO ASP SER LYS ASN TRP          
SEQRES  29 R  389  GLN TYR GLN GLU THR ILE LYS LYS GLY ASP LEU LEU LEU          
SEQRES  30 R  389  ASN ARG VAL GLN LYS LEU SER ARG VAL ILE ASN MET              
SEQRES   1 S  534  MET LYS GLN GLU GLY SER ALA ARG ARG ARG GLY ALA ASP          
SEQRES   2 S  534  LYS ALA LYS PRO PRO PRO GLY GLY GLY GLU GLN GLU PRO          
SEQRES   3 S  534  PRO PRO PRO PRO ALA PRO GLN ASP VAL GLU MET LYS GLU          
SEQRES   4 S  534  GLU ALA ALA THR GLY GLY GLY SER THR GLY GLU ALA ASP          
SEQRES   5 S  534  GLY LYS THR ALA ALA ALA ALA ALA GLU HIS SER GLN ARG          
SEQRES   6 S  534  GLU LEU ASP THR VAL THR LEU GLU ASP ILE LYS GLU HIS          
SEQRES   7 S  534  VAL LYS GLN LEU GLU LYS ALA VAL SER GLY LYS GLU PRO          
SEQRES   8 S  534  ARG PHE VAL LEU ARG ALA LEU ARG MET LEU PRO SER THR          
SEQRES   9 S  534  SER ARG ARG LEU ASN HIS TYR VAL LEU TYR LYS ALA VAL          
SEQRES  10 S  534  GLN GLY PHE PHE THR SER ASN ASN ALA THR ARG ASP PHE          
SEQRES  11 S  534  LEU LEU PRO PHE LEU GLU GLU PRO MET ASP THR GLU ALA          
SEQRES  12 S  534  ASP LEU GLN PHE ARG PRO ARG THR GLY LYS ALA ALA SER          
SEQRES  13 S  534  THR PRO LEU LEU PRO GLU VAL GLU ALA TYR LEU GLN LEU          
SEQRES  14 S  534  LEU VAL VAL ILE PHE MET MET ASN SER LYS ARG TYR LYS          
SEQRES  15 S  534  GLU ALA GLN LYS ILE SER ASP ASP LEU MET GLN LYS ILE          
SEQRES  16 S  534  SER THR GLN ASN ARG ARG ALA LEU ASP LEU VAL ALA ALA          
SEQRES  17 S  534  LYS CYS TYR TYR TYR HIS ALA ARG VAL TYR GLU PHE LEU          
SEQRES  18 S  534  ASP LYS LEU ASP VAL VAL ARG SER PHE LEU HIS ALA ARG          
SEQRES  19 S  534  LEU ARG THR ALA THR LEU ARG HIS ASP ALA ASP GLY GLN          
SEQRES  20 S  534  ALA THR LEU LEU ASN LEU LEU LEU ARG ASN TYR LEU HIS          
SEQRES  21 S  534  TYR SER LEU TYR ASP GLN ALA GLU LYS LEU VAL SER LYS          
SEQRES  22 S  534  SER VAL PHE PRO GLU GLN ALA ASN ASN ASN GLU TRP ALA          
SEQRES  23 S  534  ARG TYR LEU TYR TYR THR GLY ARG ILE LYS ALA ILE GLN          
SEQRES  24 S  534  LEU GLU TYR SER GLU ALA ARG ARG THR MET THR ASN ALA          
SEQRES  25 S  534  LEU ARG LYS ALA PRO GLN HIS THR ALA VAL GLY PHE LYS          
SEQRES  26 S  534  GLN THR VAL HIS LYS LEU LEU ILE VAL VAL GLU LEU LEU          
SEQRES  27 S  534  LEU GLY GLU ILE PRO ASP ARG LEU GLN PHE ARG GLN PRO          
SEQRES  28 S  534  SER LEU LYS ARG SER LEU MET PRO TYR PHE LEU LEU THR          
SEQRES  29 S  534  GLN ALA VAL ARG THR GLY ASN LEU ALA LYS PHE ASN GLN          
SEQRES  30 S  534  VAL LEU ASP GLN PHE GLY GLU LYS PHE GLN ALA ASP GLY          
SEQRES  31 S  534  THR TYR THR LEU ILE ILE ARG LEU ARG HIS ASN VAL ILE          
SEQRES  32 S  534  LYS THR GLY VAL ARG MET ILE SER LEU SER TYR SER ARG          
SEQRES  33 S  534  ILE SER LEU ALA ASP ILE ALA GLN LYS LEU GLN LEU ASP          
SEQRES  34 S  534  SER PRO GLU ASP ALA GLU PHE ILE VAL ALA LYS ALA ILE          
SEQRES  35 S  534  ARG ASP GLY VAL ILE GLU ALA SER ILE ASN HIS GLU LYS          
SEQRES  36 S  534  GLY TYR VAL GLN SER LYS GLU MET ILE ASP ILE TYR SER          
SEQRES  37 S  534  THR ARG GLU PRO GLN LEU ALA PHE HIS GLN ARG ILE SER          
SEQRES  38 S  534  PHE CYS LEU ASP ILE HIS ASN MET SER VAL LYS ALA MET          
SEQRES  39 S  534  ARG PHE PRO PRO LYS SER TYR ASN LYS ASP LEU GLU SER          
SEQRES  40 S  534  ALA GLU GLU ARG ARG GLU ARG GLU GLN GLN ASP LEU GLU          
SEQRES  41 S  534  PHE ALA LYS GLU MET ALA GLU ASP ASP ASP ASP SER PHE          
SEQRES  42 S  534  PRO                                                          
SEQRES   1 T  350  MET PHE ILE LYS GLY ARG ALA PRO ARG ALA PRO PRO ARG          
SEQRES   2 T  350  GLU ARG ARG ARG ALA THR ARG GLY GLY LEU ARG GLN VAL          
SEQRES   3 T  350  VAL ALA PRO PRO ARG ALA LEU GLY SER THR SER ARG PRO          
SEQRES   4 T  350  HIS PHE ARG ARG ALA SER VAL CYS ARG ARG ARG CYS ARG          
SEQRES   5 T  350  LYS SER GLY GLY LEU LEU ALA ALA SER ARG LYS MET ALA          
SEQRES   6 T  350  ALA ALA ALA VAL ASN GLY ALA ALA GLY PHE SER SER SER          
SEQRES   7 T  350  GLY PRO ALA ALA THR SER GLY ALA VAL LEU GLN ALA ALA          
SEQRES   8 T  350  THR GLY MET TYR GLU GLN LEU LYS GLY GLU TRP ASN ARG          
SEQRES   9 T  350  LYS SER PRO ASN LEU SER LYS CYS GLY GLU GLU LEU GLY          
SEQRES  10 T  350  ARG LEU LYS LEU VAL LEU LEU GLU LEU ASN PHE LEU PRO          
SEQRES  11 T  350  THR THR GLY THR LYS LEU THR LYS GLN GLN LEU ILE LEU          
SEQRES  12 T  350  ALA ARG ASP ILE LEU GLU ILE GLY ALA GLN TRP SER ILE          
SEQRES  13 T  350  LEU ARG LYS ASP ILE PRO SER PHE GLU ARG TYR MET ALA          
SEQRES  14 T  350  GLN LEU LYS CYS TYR TYR PHE ASP TYR LYS GLU GLN LEU          
SEQRES  15 T  350  PRO GLU SER ALA TYR MET HIS GLN LEU LEU GLY LEU ASN          
SEQRES  16 T  350  LEU LEU PHE LEU LEU SER GLN ASN ARG VAL ALA GLU PHE          
SEQRES  17 T  350  HIS THR GLU LEU GLU ARG LEU PRO ALA LYS ASP ILE GLN          
SEQRES  18 T  350  THR ASN VAL TYR ILE LYS HIS PRO VAL SER LEU GLU GLN          
SEQRES  19 T  350  TYR LEU MET GLU GLY SER TYR ASN LYS VAL PHE LEU ALA          
SEQRES  20 T  350  LYS GLY ASN ILE PRO ALA GLU SER TYR THR PHE PHE ILE          
SEQRES  21 T  350  ASP ILE LEU LEU ASP THR ILE ARG ASP GLU ILE ALA GLY          
SEQRES  22 T  350  CYS ILE GLU LYS ALA TYR GLU LYS ILE LEU PHE THR GLU          
SEQRES  23 T  350  ALA THR ARG ILE LEU PHE PHE ASN THR PRO LYS LYS MET          
SEQRES  24 T  350  THR ASP TYR ALA LYS LYS ARG GLY TRP VAL LEU GLY PRO          
SEQRES  25 T  350  ASN ASN TYR TYR SER PHE ALA SER GLN GLN GLN LYS PRO          
SEQRES  26 T  350  GLU ASP THR THR ILE PRO SER THR GLU LEU ALA LYS GLN          
SEQRES  27 T  350  VAL ILE GLU TYR ALA ARG GLN LEU GLU MET ILE VAL              
SEQRES   1 U  324  MET PRO GLU LEU ALA VAL GLN LYS VAL VAL VAL HIS PRO          
SEQRES   2 U  324  LEU VAL LEU LEU SER VAL VAL ASP HIS PHE ASN ARG ILE          
SEQRES   3 U  324  GLY LYS VAL GLY ASN GLN LYS ARG VAL VAL GLY VAL LEU          
SEQRES   4 U  324  LEU GLY SER TRP GLN LYS LYS VAL LEU ASP VAL SER ASN          
SEQRES   5 U  324  SER PHE ALA VAL PRO PHE ASP GLU ASP ASP LYS ASP ASP          
SEQRES   6 U  324  SER VAL TRP PHE LEU ASP HIS ASP TYR LEU GLU ASN MET          
SEQRES   7 U  324  TYR GLY MET PHE LYS LYS VAL ASN ALA ARG GLU ARG ILE          
SEQRES   8 U  324  VAL GLY TRP TYR HIS THR GLY PRO LYS LEU HIS LYS ASN          
SEQRES   9 U  324  ASP ILE ALA ILE ASN GLU LEU MET LYS ARG TYR CYS PRO          
SEQRES  10 U  324  ASN SER VAL LEU VAL ILE ILE ASP VAL LYS PRO LYS ASP          
SEQRES  11 U  324  LEU GLY LEU PRO THR GLU ALA TYR ILE SER VAL GLU GLU          
SEQRES  12 U  324  VAL HIS ASP ASP GLY THR PRO THR SER LYS THR PHE GLU          
SEQRES  13 U  324  HIS VAL THR SER GLU ILE GLY ALA GLU GLU ALA GLU GLU          
SEQRES  14 U  324  VAL GLY VAL GLU HIS LEU LEU ARG ASP ILE LYS ASP THR          
SEQRES  15 U  324  THR VAL GLY THR LEU SER GLN ARG ILE THR ASN GLN VAL          
SEQRES  16 U  324  HIS GLY LEU LYS GLY LEU ASN SER LYS LEU LEU ASP ILE          
SEQRES  17 U  324  ARG SER TYR LEU GLU LYS VAL ALA THR GLY LYS LEU PRO          
SEQRES  18 U  324  ILE ASN HIS GLN ILE ILE TYR GLN LEU GLN ASP VAL PHE          
SEQRES  19 U  324  ASN LEU LEU PRO ASP VAL SER LEU GLN GLU PHE VAL LYS          
SEQRES  20 U  324  ALA PHE TYR LEU LYS THR ASN ASP GLN MET VAL VAL VAL          
SEQRES  21 U  324  TYR LEU ALA SER LEU ILE ARG SER VAL VAL ALA LEU HIS          
SEQRES  22 U  324  ASN LEU ILE ASN ASN LYS ILE ALA ASN ARG ASP ALA GLU          
SEQRES  23 U  324  LYS LYS GLU GLY GLN GLU LYS GLU GLU SER LYS LYS ASP          
SEQRES  24 U  324  ARG LYS GLU ASP LYS GLU LYS ASP LYS ASP LYS GLU LYS          
SEQRES  25 U  324  SER ASP VAL LYS LYS GLU GLU LYS LYS GLU LYS LYS              
SEQRES   1 V  310  MET ASP ARG LEU LEU ARG LEU GLY GLY GLY MET PRO GLY          
SEQRES   2 V  310  LEU GLY GLN GLY PRO PRO THR ASP ALA PRO ALA VAL ASP          
SEQRES   3 V  310  THR ALA GLU GLN VAL TYR ILE SER SER LEU ALA LEU LEU          
SEQRES   4 V  310  LYS MET LEU LYS HIS GLY ARG ALA GLY VAL PRO MET GLU          
SEQRES   5 V  310  VAL MET GLY LEU MET LEU GLY GLU PHE VAL ASP ASP TYR          
SEQRES   6 V  310  THR VAL ARG VAL ILE ASP VAL PHE ALA MET PRO GLN SER          
SEQRES   7 V  310  GLY THR GLY VAL SER VAL GLU ALA VAL ASP PRO VAL PHE          
SEQRES   8 V  310  GLN ALA LYS MET LEU ASP MET LEU LYS GLN THR GLY ARG          
SEQRES   9 V  310  PRO GLU MET VAL VAL GLY TRP TYR HIS SER HIS PRO GLY          
SEQRES  10 V  310  PHE GLY CYS TRP LEU SER GLY VAL ASP ILE ASN THR GLN          
SEQRES  11 V  310  GLN SER PHE GLU ALA LEU SER GLU ARG ALA VAL ALA VAL          
SEQRES  12 V  310  VAL VAL ASP PRO ILE GLN SER VAL LYS GLY LYS VAL VAL          
SEQRES  13 V  310  ILE ASP ALA PHE ARG LEU ILE ASN ALA ASN MET MET VAL          
SEQRES  14 V  310  LEU GLY HIS GLU PRO ARG GLN THR THR SER ASN LEU GLY          
SEQRES  15 V  310  HIS LEU ASN LYS PRO SER ILE GLN ALA LEU ILE HIS GLY          
SEQRES  16 V  310  LEU ASN ARG HIS TYR TYR SER ILE THR ILE ASN TYR ARG          
SEQRES  17 V  310  LYS ASN GLU LEU GLU GLN LYS MET LEU LEU ASN LEU HIS          
SEQRES  18 V  310  LYS LYS SER TRP MET GLU GLY LEU THR LEU GLN ASP TYR          
SEQRES  19 V  310  SER GLU HIS CYS LYS HIS ASN GLU SER VAL VAL LYS GLU          
SEQRES  20 V  310  MET LEU GLU LEU ALA LYS ASN TYR ASN LYS ALA VAL GLU          
SEQRES  21 V  310  GLU GLU ASP LYS MET THR PRO GLU GLN LEU ALA ILE LYS          
SEQRES  22 V  310  ASN VAL GLY LYS GLN ASP PRO LYS ARG HIS LEU GLU GLU          
SEQRES  23 V  310  HIS VAL ASP VAL LEU MET THR SER ASN ILE VAL GLN CYS          
SEQRES  24 V  310  LEU ALA ALA MET LEU ASP THR VAL VAL PHE LYS                  
SEQRES   1 W  377  MET VAL LEU GLU SER THR MET VAL CYS VAL ASP ASN SER          
SEQRES   2 W  377  GLU TYR MET ARG ASN GLY ASP PHE LEU PRO THR ARG LEU          
SEQRES   3 W  377  GLN ALA GLN GLN ASP ALA VAL ASN ILE VAL CYS HIS SER          
SEQRES   4 W  377  LYS THR ARG SER ASN PRO GLU ASN ASN VAL GLY LEU ILE          
SEQRES   5 W  377  THR LEU ALA ASN ASP CYS GLU VAL LEU THR THR LEU THR          
SEQRES   6 W  377  PRO ASP THR GLY ARG ILE LEU SER LYS LEU HIS THR VAL          
SEQRES   7 W  377  GLN PRO LYS GLY LYS ILE THR PHE CYS THR GLY ILE ARG          
SEQRES   8 W  377  VAL ALA HIS LEU ALA LEU LYS HIS ARG GLN GLY LYS ASN          
SEQRES   9 W  377  HIS LYS MET ARG ILE ILE ALA PHE VAL GLY SER PRO VAL          
SEQRES  10 W  377  GLU ASP ASN GLU LYS ASP LEU VAL LYS LEU ALA LYS ARG          
SEQRES  11 W  377  LEU LYS LYS GLU LYS VAL ASN VAL ASP ILE ILE ASN PHE          
SEQRES  12 W  377  GLY GLU GLU GLU VAL ASN THR GLU LYS LEU THR ALA PHE          
SEQRES  13 W  377  VAL ASN THR LEU ASN GLY LYS ASP GLY THR GLY SER HIS          
SEQRES  14 W  377  LEU VAL THR VAL PRO PRO GLY PRO SER LEU ALA ASP ALA          
SEQRES  15 W  377  LEU ILE SER SER PRO ILE LEU ALA GLY GLU GLY GLY ALA          
SEQRES  16 W  377  MET LEU GLY LEU GLY ALA SER ASP PHE GLU PHE GLY VAL          
SEQRES  17 W  377  ASP PRO SER ALA ASP PRO GLU LEU ALA LEU ALA LEU ARG          
SEQRES  18 W  377  VAL SER MET GLU GLU GLN ARG GLN ARG GLN GLU GLU GLU          
SEQRES  19 W  377  ALA ARG ARG ALA ALA ALA ALA SER ALA ALA GLU ALA GLY          
SEQRES  20 W  377  ILE ALA THR THR GLY THR GLU ASP SER ASP ASP ALA LEU          
SEQRES  21 W  377  LEU LYS MET THR ILE SER GLN GLN GLU PHE GLY ARG THR          
SEQRES  22 W  377  GLY LEU PRO ASP LEU SER SER MET THR GLU GLU GLU GLN          
SEQRES  23 W  377  ILE ALA TYR ALA MET GLN MET SER LEU GLN GLY ALA GLU          
SEQRES  24 W  377  PHE GLY GLN ALA GLU SER ALA ASP ILE ASP ALA SER SER          
SEQRES  25 W  377  ALA MET ASP THR SER GLU PRO ALA LYS GLU GLU ASP ASP          
SEQRES  26 W  377  TYR ASP VAL MET GLN ASP PRO GLU PHE LEU GLN SER VAL          
SEQRES  27 W  377  LEU GLU ASN LEU PRO GLY VAL ASP PRO ASN ASN GLU ALA          
SEQRES  28 W  377  ILE ARG ASN ALA MET GLY SER LEU ALA SER GLN ALA THR          
SEQRES  29 W  377  LYS ASP GLY LYS LYS ASP LYS LYS GLU GLU ASP LYS LYS          
SEQRES   1 Y   70  MET SER GLU LYS LYS GLN PRO VAL ASP LEU GLY LEU LEU          
SEQRES   2 Y   70  GLU GLU ASP ASP GLU PHE GLU GLU PHE PRO ALA GLU ASP          
SEQRES   3 Y   70  TRP ALA GLY LEU ASP GLU ASP GLU ASP ALA HIS VAL TRP          
SEQRES   4 Y   70  GLU ASP ASN TRP ASP ASP ASP ASN VAL GLU ASP ASP PHE          
SEQRES   5 Y   70  SER ASN GLN LEU ARG ALA GLU LEU GLU LYS HIS GLY TYR          
SEQRES   6 Y   70  LYS MET GLU THR SER                                          
HELIX    1 AA1 MET Z   58  GLU Z   65  1                                   8    
HELIX    2 AA2 ASP Z   67  ILE Z   82  1                                  16    
HELIX    3 AA3 LYS Z   94  ARG Z  100  1                                   7    
HELIX    4 AA4 HIS Z  102  ASN Z  112  1                                  11    
HELIX    5 AA5 GLU Z  117  THR Z  132  1                                  16    
HELIX    6 AA6 ARG Z  137  VAL Z  145  1                                   9    
HELIX    7 AA7 HIS Z  156  ASP Z  174  1                                  19    
HELIX    8 AA8 ARG Z  181  ASN Z  199  1                                  19    
HELIX    9 AA9 ALA Z  200  GLU Z  212  1                                  13    
HELIX   10 AB1 VAL Z  214  ILE Z  221  1                                   8    
HELIX   11 AB2 ALA Z  225  VAL Z  240  1                                  16    
HELIX   12 AB3 SER Z  246  LYS Z  258  1                                  13    
HELIX   13 AB4 ARG Z  261  LEU Z  270  1                                  10    
HELIX   14 AB5 ASP Z  274  CYS Z  285  1                                  12    
HELIX   15 AB6 ASP Z  287  HIS Z  301  1                                  15    
HELIX   16 AB7 GLU Z  319  ASN Z  327  1                                   9    
HELIX   17 AB8 LEU Z  333  GLU Z  341  1                                   9    
HELIX   18 AB9 LYS Z  343  ARG Z  357  1                                  15    
HELIX   19 AC1 SER Z  367  ASN Z  382  1                                  16    
HELIX   20 AC2 ASP Z  388  ASP Z  394  1                                   7    
HELIX   21 AC3 ASN Z  396  ASN Z  402  1                                   7    
HELIX   22 AC4 ASP Z  404  LEU Z  419  1                                  16    
HELIX   23 AC5 VAL Z  422  TYR Z  434  1                                  13    
HELIX   24 AC6 GLU Z  437  SER Z  453  1                                  17    
HELIX   25 AC7 PRO Z  461  HIS Z  472  1                                  12    
HELIX   26 AC8 SER Z  474  ALA Z  490  1                                  17    
HELIX   27 AC9 ARG Z  494  ASP Z  507  1                                  14    
HELIX   28 AD1 THR Z  518  ALA Z  526  1                                   9    
HELIX   29 AD2 ASN Z  531  LYS Z  545  1                                  15    
HELIX   30 AD3 LYS Z  551  HIS Z  566  1                                  16    
HELIX   31 AD4 GLY Z  570  ALA Z  572  5                                   3    
HELIX   32 AD5 ILE Z  573  VAL Z  583  1                                  11    
HELIX   33 AD6 PHE Z  587  ALA Z  601  1                                  15    
HELIX   34 AD7 ASN Z  605  SER Z  617  1                                  13    
HELIX   35 AD8 GLY Z  651  GLY Z  663  1                                  13    
HELIX   36 AD9 GLU Z  664  TYR Z  681  1                                  18    
HELIX   37 AE1 GLU Z  683  VAL Z  699  1                                  17    
HELIX   38 AE2 ARG Z  703  HIS Z  715  1                                  13    
HELIX   39 AE3 ASP Z  718  GLY Z  733  1                                  16    
HELIX   40 AE4 ARG Z  740  GLN Z  750  1                                  11    
HELIX   41 AE5 ASP Z  755  HIS Z  770  1                                  16    
HELIX   42 AE6 SER Z  789  VAL Z  801  1                                  13    
HELIX   43 AE7 HIS Z  815  MET Z  825  5                                  11    
HELIX   44 AE8 SER 1   82  LEU 1  104  1                                  23    
HELIX   45 AE9 LEU 1  109  TYR 1  124  1                                  16    
HELIX   46 AF1 GLY 1  165  TYR 1  177  1                                  13    
HELIX   47 AF2 THR 1  182  ASP 1  201  1                                  20    
HELIX   48 AF3 THR 2   91  GLY 2  114  1                                  24    
HELIX   49 AF4 ARG 2  118  GLN 2  134  1                                  17    
HELIX   50 AF5 GLY 2  173  PHE 2  185  1                                  13    
HELIX   51 AF6 GLU 2  190  ASP 2  209  1                                  20    
HELIX   52 AF7 GLU 2  248  THR 2  252  5                                   5    
HELIX   53 AF8 LEU 3   56  GLY 3   79  1                                  24    
HELIX   54 AF9 LYS 3   83  ARG 3   99  1                                  17    
HELIX   55 AG1 CYS 3  142  TRP 3  154  1                                  13    
HELIX   56 AG2 ASP 3  159  ASP 3  176  1                                  18    
HELIX   57 AG3 GLU 4   49  GLY 4   72  1                                  24    
HELIX   58 AG4 SER 4   76  LEU 4   92  1                                  17    
HELIX   59 AG5 GLY 4  135  TYR 4  147  1                                  13    
HELIX   60 AG6 SER 4  152  PHE 4  171  1                                  20    
HELIX   61 AG7 GLY 5  107  LYS 5  130  1                                  24    
HELIX   62 AG8 SER 5  134  LYS 5  150  1                                  17    
HELIX   63 AG9 GLY 5  190  TYR 5  202  1                                  13    
HELIX   64 AH1 GLU 5  207  ASP 5  226  1                                  20    
HELIX   65 AH2 PHE 6   85  ASN 6  107  1                                  23    
HELIX   66 AH3 THR 6  112  ARG 6  127  1                                  16    
HELIX   67 AH4 ALA 6  169  GLY 6  182  1                                  14    
HELIX   68 AH5 SER 6  195  ALA 6  211  1                                  17    
HELIX   69 AH6 TYR 7  102  MET 7  115  1                                  14    
HELIX   70 AH7 SER 7  129  MET 7  148  1                                  20    
HELIX   71 AH8 GLY 7  185  LEU 7  190  1                                   6    
HELIX   72 AH9 ALA 7  191  LEU 7  199  1                                   9    
HELIX   73 AI1 LYS 7  201  SER 7  206  1                                   6    
HELIX   74 AI2 GLN 7  207  GLU 7  209  5                                   3    
HELIX   75 AI3 ALA 7  210  ASP 7  225  1                                  16    
HELIX   76 AI4 TRP 7  254  ILE 7  260  1                                   7    
HELIX   77 AI5 LEU A   22  ALA A   31  1                                  10    
HELIX   78 AI6 MET A   83  GLY A  106  1                                  24    
HELIX   79 AI7 PRO A  110  ASN A  128  1                                  19    
HELIX   80 AI8 LYS A  171  LYS A  184  1                                  14    
HELIX   81 AI9 THR A  190  SER A  207  1                                  18    
HELIX   82 AJ1 THR A  231  GLU A  244  1                                  14    
HELIX   83 AJ2 LEU B   19  GLY B   31  1                                  13    
HELIX   84 AJ3 MET B   79  TYR B  101  1                                  23    
HELIX   85 AJ4 PRO B  106  SER B  124  1                                  19    
HELIX   86 AJ5 ASN B  166  TYR B  178  1                                  13    
HELIX   87 AJ6 GLU B  183  PHE B  199  1                                  17    
HELIX   88 AJ7 THR B  222  ILE B  233  1                                  12    
HELIX   89 AJ8 LEU C   18  ALA C   31  1                                  14    
HELIX   90 AJ9 ILE C   79  GLN C  102  1                                  24    
HELIX   91 AK1 PRO C  106  PHE C  124  1                                  19    
HELIX   92 AK2 ASN C  167  TYR C  179  1                                  13    
HELIX   93 AK3 THR C  185  MET C  201  1                                  17    
HELIX   94 AK4 SER C  207  GLU C  209  5                                   3    
HELIX   95 AK5 LYS C  229  LYS C  259  1                                  31    
HELIX   96 AK6 LEU D   16  GLY D   29  1                                  14    
HELIX   97 AK7 LEU D   76  VAL D   98  1                                  23    
HELIX   98 AK8 THR D  103  SER D  121  1                                  19    
HELIX   99 AK9 GLY D  164  THR D  177  1                                  14    
HELIX  100 AL1 THR D  183  GLN D  200  1                                  18    
HELIX  101 AL2 GLY D  202  LYS D  204  5                                   3    
HELIX  102 AL3 ASN D  221  ALA D  247  1                                  27    
HELIX  103 AL4 LEU E   21  LEU E   33  1                                  13    
HELIX  104 AL5 LEU E   81  ASN E  104  1                                  24    
HELIX  105 AL6 THR E  108  ALA E  120  1                                  13    
HELIX  106 AL7 ALA E  173  TYR E  185  1                                  13    
HELIX  107 AL8 THR E  190  MET E  206  1                                  17    
HELIX  108 AL9 THR E  230  ILE E  241  1                                  12    
HELIX  109 AM1 PHE F    2  ASP F    9  1                                   8    
HELIX  110 AM2 ILE F   19  GLY F   32  1                                  14    
HELIX  111 AM3 LEU F   77  PHE F   99  1                                  23    
HELIX  112 AM4 PRO F  104  GLN F  121  1                                  18    
HELIX  113 AM5 ARG F  164  HIS F  175  1                                  12    
HELIX  114 AM6 MET F  176  MET F  180  5                                   5    
HELIX  115 AM7 ASN F  183  LEU F  199  1                                  17    
HELIX  116 AM8 ASP F  227  LEU F  233  5                                   7    
HELIX  117 AM9 VAL G   21  SER G   34  1                                  14    
HELIX  118 AN1 LEU G   81  GLY G  104  1                                  24    
HELIX  119 AN2 PRO G  108  TYR G  126  1                                  19    
HELIX  120 AN3 ALA G  169  LYS G  179  1                                  11    
HELIX  121 AN4 THR G  186  GLU G  204  1                                  19    
HELIX  122 AN5 PRO G  229  LEU G  244  1                                  16    
HELIX  123 AN6 LYS H   46  THR H   70  1                                  25    
HELIX  124 AN7 CYS H  180  VAL H  191  1                                  12    
HELIX  125 AN8 VAL H  191  HIS H  197  1                                   7    
HELIX  126 AN9 HIS H  197  GLY H  205  1                                   9    
HELIX  127 AO1 GLY H  221  ASP H  234  1                                  14    
HELIX  128 AO2 GLY H  242  VAL H  246  1                                   5    
HELIX  129 AO3 GLY H  251  LYS H  267  1                                  17    
HELIX  130 AO4 GLY H  291  GLY H  308  1                                  18    
HELIX  131 AO5 ARG H  323  LEU H  327  5                                   5    
HELIX  132 AO6 ASP H  328  ARG H  333  1                                   6    
HELIX  133 AO7 ASP H  347  ALA H  359  1                                  13    
HELIX  134 AO8 ARG H  369  CYS H  377  1                                   9    
HELIX  135 AO9 THR H  381  ARG H  400  1                                  20    
HELIX  136 AP1 GLU H  406  ALA H  421  1                                  16    
HELIX  137 AP2 ARG I   80  GLY I  104  1                                  25    
HELIX  138 AP3 LEU I  190  HIS I  207  1                                  18    
HELIX  139 AP4 HIS I  207  GLY I  215  1                                   9    
HELIX  140 AP5 GLY I  231  SER I  244  1                                  14    
HELIX  141 AP6 SER I  253  ILE I  256  5                                   4    
HELIX  142 AP7 GLY I  261  HIS I  277  1                                  17    
HELIX  143 AP8 GLU I  302  PHE I  319  1                                  18    
HELIX  144 AP9 ASP I  338  ARG I  343  1                                   6    
HELIX  145 AQ1 ASP I  357  MET I  372  1                                  16    
HELIX  146 AQ2 THR I  379  LYS I  387  1                                   9    
HELIX  147 AQ3 SER I  391  GLU I  409  1                                  19    
HELIX  148 AQ4 THR I  415  GLN I  431  1                                  17    
HELIX  149 AQ5 SER J   26  LEU J   66  1                                  41    
HELIX  150 AQ6 LEU J  154  HIS J  171  1                                  18    
HELIX  151 AQ7 PRO J  172  GLY J  179  1                                   8    
HELIX  152 AQ8 GLY J  195  ASP J  208  1                                  14    
HELIX  153 AQ9 SER J  217  VAL J  220  5                                   4    
HELIX  154 AR1 GLY J  225  ALA J  242  1                                  18    
HELIX  155 AR2 ASP J  266  ASP J  281  1                                  16    
HELIX  156 AR3 ASP J  302  ARG J  307  1                                   6    
HELIX  157 AR4 ASN J  321  ARG J  334  1                                  14    
HELIX  158 AR5 ASN J  343  MET J  351  1                                   9    
HELIX  159 AR6 SER J  355  GLU J  373  1                                  19    
HELIX  160 AR7 THR J  379  GLU J  396  1                                  18    
HELIX  161 AR8 ARG K   43  GLN K   83  1                                  41    
HELIX  162 AR9 MET K  170  HIS K  187  1                                  18    
HELIX  163 AS1 HIS K  187  GLY K  195  1                                   9    
HELIX  164 AS2 GLY K  211  THR K  224  1                                  14    
HELIX  165 AS3 ARG K  245  ARG K  248  5                                   4    
HELIX  166 AS4 ASP K  249  ASN K  257  1                                   9    
HELIX  167 AS5 GLU K  266  ILE K  270  5                                   5    
HELIX  168 AS6 ARG K  283  PHE K  299  1                                  17    
HELIX  169 AS7 ASP K  337  ASN K  353  1                                  17    
HELIX  170 AS8 ASP K  359  ARG K  366  1                                   8    
HELIX  171 AS9 SER K  371  GLU K  389  1                                  19    
HELIX  172 AT1 LEU K  395  LYS K  408  1                                  14    
HELIX  173 AT2 LYS L   20  SER L   52  1                                  33    
HELIX  174 AT3 LEU L  138  ASN L  155  1                                  18    
HELIX  175 AT4 PRO L  156  GLY L  163  1                                   8    
HELIX  176 AT5 GLY L  179  ASP L  192  1                                  14    
HELIX  177 AT6 SER L  200  VAL L  204  1                                   5    
HELIX  178 AT7 GLY L  209  GLN L  226  1                                  18    
HELIX  179 AT8 ALA L  249  GLY L  266  1                                  18    
HELIX  180 AT9 ASN L  305  GLY L  318  1                                  14    
HELIX  181 AU1 ASP L  327  SER L  335  1                                   9    
HELIX  182 AU2 ASN L  339  ASP L  358  1                                  20    
HELIX  183 AU3 VAL L  363  LYS L  378  1                                  16    
HELIX  184 AU4 ILE M   52  THR M   85  1                                  34    
HELIX  185 AU5 LEU M  191  VAL M  203  1                                  13    
HELIX  186 AU6 VAL M  203  HIS M  208  1                                   6    
HELIX  187 AU7 HIS M  208  GLY M  216  1                                   9    
HELIX  188 AU8 GLY M  232  LYS M  245  1                                  14    
HELIX  189 AU9 GLY M  253  VAL M  257  1                                   5    
HELIX  190 AV1 GLY M  262  ALA M  279  1                                  18    
HELIX  191 AV2 ASP M  303  GLY M  319  1                                  17    
HELIX  192 AV3 ASN M  358  SER M  370  1                                  13    
HELIX  193 AV4 ASN M  380  THR M  388  1                                   9    
HELIX  194 AV5 ASN M  392  GLY M  411  1                                  20    
HELIX  195 AV6 THR M  416  GLU M  426  1                                  11    
HELIX  196 AV7 ALA N    5  SER N   10  1                                   6    
HELIX  197 AV8 LEU N   11  GLU N   14  5                                   4    
HELIX  198 AV9 GLU N   16  SER N   39  1                                  24    
HELIX  199 AW1 SER N   41  ASP N   51  1                                  11    
HELIX  200 AW2 SER N   56  GLY N   72  1                                  17    
HELIX  201 AW3 ALA N   73  GLY N   85  1                                  13    
HELIX  202 AW4 SER N   94  ASP N  117  1                                  24    
HELIX  203 AW5 ASP N  127  HIS N  145  1                                  19    
HELIX  204 AW6 LYS N  146  THR N  157  1                                  12    
HELIX  205 AW7 ARG N  159  ILE N  167  1                                   9    
HELIX  206 AW8 ASP N  172  MET N  188  1                                  17    
HELIX  207 AW9 ASN N  190  LEU N  208  1                                  19    
HELIX  208 AX1 ASP N  212  ASP N  224  1                                  13    
HELIX  209 AX2 ASP N  225  ASP N  240  1                                  16    
HELIX  210 AX3 ASN N  241  ALA N  256  1                                  16    
HELIX  211 AX4 SER N  257  GLY N  272  1                                  16    
HELIX  212 AX5 GLY N  331  ASN N  346  1                                  16    
HELIX  213 AX6 LEU N  350  ASP N  358  1                                   9    
HELIX  214 AX7 SER N  363  CYS N  378  1                                  16    
HELIX  215 AX8 ASP N  383  ASN N  389  1                                   7    
HELIX  216 AX9 LEU N  390  ALA N  396  1                                   7    
HELIX  217 AY1 THR N  397  LYS N  413  1                                  17    
HELIX  218 AY2 LYS N  417  ALA N  424  1                                   8    
HELIX  219 AY3 SER N  435  HIS N  450  1                                  16    
HELIX  220 AY4 GLY N  454  ALA N  468  1                                  15    
HELIX  221 AY5 ASP N  471  MET N  486  1                                  16    
HELIX  222 AY6 ARG N  490  ASP N  504  1                                  15    
HELIX  223 AY7 ASP N  505  LEU N  521  1                                  17    
HELIX  224 AY8 ASN N  525  THR N  539  1                                  15    
HELIX  225 AY9 HIS N  541  MET N  556  1                                  16    
HELIX  226 AZ1 ARG N  559  GLU N  562  5                                   4    
HELIX  227 AZ2 ALA N  563  ASP N  573  1                                  11    
HELIX  228 AZ3 ASP N  575  CYS N  591  1                                  17    
HELIX  229 AZ4 ASN N  595  ASP N  609  1                                  15    
HELIX  230 AZ5 ASN N  611  LEU N  626  1                                  16    
HELIX  231 AZ6 GLN N  632  SER N  643  1                                  12    
HELIX  232 AZ7 ASN N  645  CYS N  660  1                                  16    
HELIX  233 AZ8 ASN N  665  ASN N  677  1                                  13    
HELIX  234 AZ9 VAL N  680  ILE N  696  1                                  17    
HELIX  235 BA1 LYS N  705  ASP N  719  1                                  15    
HELIX  236 BA2 ASP N  723  ASP N  738  1                                  16    
HELIX  237 BA3 ALA N  739  HIS N  742  5                                   4    
HELIX  238 BA4 HIS N  756  THR N  767  1                                  12    
HELIX  239 BA5 LEU N  775  ALA N  782  5                                   8    
HELIX  240 BA6 MET N  885  LYS N  890  1                                   6    
HELIX  241 BA7 LYS O    2  ASN O   13  1                                  12    
HELIX  242 BA8 ALA O   20  THR O   30  1                                  11    
HELIX  243 BA9 VAL O   41  GLN O   46  1                                   6    
HELIX  244 BB1 ILE O   57  VAL O   71  1                                  15    
HELIX  245 BB2 VAL O   77  THR O   88  1                                  12    
HELIX  246 BB3 ASP O   89  ARG O  101  1                                  13    
HELIX  247 BB4 ASP O  108  GLY O  126  1                                  19    
HELIX  248 BB5 ASP O  127  LEU O  145  1                                  19    
HELIX  249 BB6 SER O  150  ILE O  166  1                                  17    
HELIX  250 BB7 ASN O  168  ASP O  184  1                                  17    
HELIX  251 BB8 PRO O  189  GLY O  207  1                                  19    
HELIX  252 BB9 PHE O  213  HIS O  219  1                                   7    
HELIX  253 BC1 ARG O  230  GLY O  243  1                                  14    
HELIX  254 BC2 VAL O  245  THR O  250  1                                   6    
HELIX  255 BC3 PRO O  259  PHE O  282  1                                  24    
HELIX  256 BC4 PHE O  293  LYS O  301  1                                   9    
HELIX  257 BC5 THR O  303  VAL O  317  1                                  15    
HELIX  258 BC6 LEU O  343  GLN O  370  1                                  28    
HELIX  259 BC7 GLN P   41  ARG P   55  1                                  15    
HELIX  260 BC8 THR P   63  LYS P   78  1                                  16    
HELIX  261 BC9 GLU P   79  ARG P   93  1                                  15    
HELIX  262 BD1 LEU P   97  GLU P  113  1                                  17    
HELIX  263 BD2 THR P  116  LEU P  128  1                                  13    
HELIX  264 BD3 GLU P  139  GLY P  157  1                                  19    
HELIX  265 BD4 ASP P  158  TYR P  174  1                                  17    
HELIX  266 BD5 GLU P  178  LYS P  197  1                                  20    
HELIX  267 BD6 ASP P  198  GLU P  216  1                                  19    
HELIX  268 BD7 THR P  219  GLY P  238  1                                  20    
HELIX  269 BD8 SER P  239  TYR P  251  1                                  13    
HELIX  270 BD9 TYR P  251  ALA P  258  1                                   8    
HELIX  271 BE1 GLU P  259  ALA P  277  1                                  19    
HELIX  272 BE2 ASN P  281  VAL P  287  1                                   7    
HELIX  273 BE3 ARG P  289  LYS P  294  1                                   6    
HELIX  274 BE4 GLU P  297  MET P  312  1                                  16    
HELIX  275 BE5 MET P  315  TYR P  324  1                                  10    
HELIX  276 BE6 LYS P  349  TYR P  369  1                                  21    
HELIX  277 BE7 MET P  375  ASP P  383  1                                   9    
HELIX  278 BE8 SER P  385  LYS P  400  1                                  16    
HELIX  279 BE9 ASP P  420  ASN P  454  1                                  35    
HELIX  280 BF1 ALA Q    4  ASP Q   19  1                                  16    
HELIX  281 BF2 ARG Q   20  HIS Q   28  1                                   9    
HELIX  282 BF3 SER Q   29  VAL Q   31  5                                   3    
HELIX  283 BF4 GLU Q   40  GLY Q   61  1                                  22    
HELIX  284 BF5 GLN Q   62  VAL Q   73  1                                  12    
HELIX  285 BF6 VAL Q   73  SER Q   79  1                                   7    
HELIX  286 BF7 SER Q   81  MET Q   99  1                                  19    
HELIX  287 BF8 ALA Q  102  LYS Q  121  1                                  20    
HELIX  288 BF9 THR Q  123  THR Q  140  1                                  18    
HELIX  289 BG1 ARG Q  142  MET Q  160  1                                  19    
HELIX  290 BG2 ALA Q  164  SER Q  181  1                                  18    
HELIX  291 BG3 ASN Q  182  ALA Q  199  1                                  18    
HELIX  292 BG4 PRO Q  203  GLU Q  222  1                                  20    
HELIX  293 BG5 ASP Q  224  SER Q  241  1                                  18    
HELIX  294 BG6 PRO Q  245  ASN Q  262  1                                  18    
HELIX  295 BG7 THR Q  263  GLY Q  273  1                                  11    
HELIX  296 BG8 GLY Q  281  ARG Q  297  1                                  17    
HELIX  297 BG9 LEU Q  299  ARG Q  314  1                                  16    
HELIX  298 BH1 ASP Q  316  GLU Q  340  1                                  25    
HELIX  299 BH2 ILE Q  347  LYS Q  355  1                                   9    
HELIX  300 BH3 SER Q  357  LYS Q  372  1                                  16    
HELIX  301 BH4 THR Q  396  LYS Q  420  1                                  25    
HELIX  302 BH5 LEU R   17  LEU R   28  1                                  12    
HELIX  303 BH6 HIS R   31  VAL R   37  1                                   7    
HELIX  304 BH7 ASP R   39  ASN R   48  1                                  10    
HELIX  305 BH8 MET R   50  LEU R   61  1                                  12    
HELIX  306 BH9 VAL R   67  LYS R   93  1                                  27    
HELIX  307 BI1 GLU R   97  GLY R  115  1                                  19    
HELIX  308 BI2 LYS R  117  LYS R  130  1                                  14    
HELIX  309 BI3 GLY R  135  MET R  152  1                                  18    
HELIX  310 BI4 ASN R  154  GLU R  169  1                                  16    
HELIX  311 BI5 ASP R  173  ARG R  192  1                                  20    
HELIX  312 BI6 PHE R  194  ASP R  203  1                                  10    
HELIX  313 BI7 ASP R  215  LEU R  231  1                                  17    
HELIX  314 BI8 GLU R  232  VAL R  240  1                                   9    
HELIX  315 BI9 GLY R  243  HIS R  251  1                                   9    
HELIX  316 BJ1 ARG R  257  CYS R  266  1                                  10    
HELIX  317 BJ2 PHE R  271  GLN R  273  5                                   3    
HELIX  318 BJ3 SER R  274  ASP R  285  1                                  12    
HELIX  319 BJ4 PHE R  288  PRO R  290  5                                   3    
HELIX  320 BJ5 HIS R  291  TYR R  311  1                                  21    
HELIX  321 BJ6 LEU R  316  PHE R  323  1                                   8    
HELIX  322 BJ7 GLY R  326  ALA R  340  1                                  15    
HELIX  323 BJ8 SER R  361  ILE R  387  1                                  27    
HELIX  324 BJ9 PRO S  158  ILE S  173  1                                  16    
HELIX  325 BK1 GLU S  183  MET S  192  1                                  10    
HELIX  326 BK2 MET S  192  GLN S  198  1                                   7    
HELIX  327 BK3 ALA S  207  VAL S  217  1                                  11    
HELIX  328 BK4 VAL S  217  ASP S  222  1                                   6    
HELIX  329 BK5 VAL S  226  ALA S  238  1                                  13    
HELIX  330 BK6 ASP S  243  TYR S  261  1                                  19    
HELIX  331 BK7 ASP S  265  VAL S  275  1                                  11    
HELIX  332 BK8 ALA S  286  LEU S  300  1                                  15    
HELIX  333 BK9 GLU S  301  ARG S  314  1                                  14    
HELIX  334 BL1 THR S  320  GLY S  340  1                                  21    
HELIX  335 BL2 ASP S  344  ARG S  349  1                                   6    
HELIX  336 BL3 LEU S  353  GLY S  370  1                                  18    
HELIX  337 BL4 ASN S  371  PHE S  382  1                                  12    
HELIX  338 BL5 PHE S  382  GLY S  390  1                                   9    
HELIX  339 BL6 THR S  393  ILE S  410  1                                  18    
HELIX  340 BL7 LEU S  419  SER S  430  1                                  12    
HELIX  341 BL8 ASP S  433  GLY S  445  1                                  13    
HELIX  342 BL9 ARG S  470  ALA S  493  1                                  24    
HELIX  343 BM1 ALA T   60  VAL T   69  1                                  10    
HELIX  344 BM2 SER T  110  LEU T  126  1                                  17    
HELIX  345 BM3 GLN T  140  LYS T  159  1                                  20    
HELIX  346 BM4 ASP T  160  PHE T  176  1                                  17    
HELIX  347 BM5 SER T  185  ASN T  203  1                                  19    
HELIX  348 BM6 ARG T  204  LEU T  215  1                                  12    
HELIX  349 BM7 LYS T  218  ASN T  223  1                                   6    
HELIX  350 BM8 ASN T  223  GLY T  239  1                                  17    
HELIX  351 BM9 SER T  240  PHE T  245  1                                   6    
HELIX  352 BN1 ASN T  250  SER T  255  1                                   6    
HELIX  353 BN2 SER T  255  TYR T  279  1                                  25    
HELIX  354 BN3 PHE T  284  LEU T  291  1                                   8    
HELIX  355 BN4 THR T  295  GLY T  307  1                                  13    
HELIX  356 BN5 ILE T  330  LEU T  346  1                                  17    
HELIX  357 BN6 HIS U   12  GLY U   27  1                                  16    
HELIX  358 BN7 ASP U   71  ASN U   86  1                                  16    
HELIX  359 BN8 LYS U  103  CYS U  116  1                                  14    
HELIX  360 BN9 GLU U  165  LEU U  176  1                                  12    
HELIX  361 BO1 ILE U  191  THR U  217  1                                  27    
HELIX  362 BO2 ASN U  223  LEU U  237  1                                  15    
HELIX  363 BO3 VAL U  246  GLY U  290  1                                  45    
HELIX  364 BO4 SER V   34  VAL V   49  1                                  16    
HELIX  365 BO5 ASP V   88  GLY V  103  1                                  16    
HELIX  366 BO6 SER V  123  SER V  137  1                                  15    
HELIX  367 BO7 ILE V  148  GLY V  153  5                                   6    
HELIX  368 BO8 ASN V  185  LEU V  196  1                                  12    
HELIX  369 BO9 ASN V  210  ASN V  219  1                                  10    
HELIX  370 BP1 SER V  235  VAL V  275  1                                  41    
HELIX  371 BP2 GLN V  278  ALA V  302  1                                  25    
HELIX  372 BP3 GLU W   14  ASN W   18  5                                   5    
HELIX  373 BP4 THR W   24  ASN W   44  1                                  21    
HELIX  374 BP5 ASP W   67  THR W   77  1                                  11    
HELIX  375 BP6 THR W   85  LEU W   97  1                                  13    
HELIX  376 BP7 ASN W  120  LYS W  135  1                                  16    
HELIX  377 BP8 GLU W  151  ASN W  161  1                                  11    
HELIX  378 BP9 ASP Y   51  HIS Y   63  1                                  13    
SHEET    1 AA1 2 LEU Z 776  THR Z 777  0                                        
SHEET    2 AA1 2 GLN Z 826  PRO Z 827 -1  O  GLN Z 826   N  THR Z 777           
SHEET    1 AA2 2 TYR Z 781  HIS Z 782  0                                        
SHEET    2 AA2 2 LEU Z 787  MET Z 788 -1  O  LEU Z 787   N  HIS Z 782           
SHEET    1 AA3 2 VAL Z 831  THR Z 832  0                                        
SHEET    2 AA3 2 PHE Z 897  VAL Z 898  1  O  VAL Z 898   N  VAL Z 831           
SHEET    1 AA4 5 PHE 1 159  GLY 1 162  0                                        
SHEET    2 AA4 5 ILE 1  37  GLN 1  41 -1  N  ILE 1  37   O  GLY 1 162           
SHEET    3 AA4 5 VAL 1  46  SER 1  52 -1  O  VAL 1  47   N  VAL 1  40           
SHEET    4 AA4 5 GLY 1 205  ALA 1 214 -1  O  ILE 1 213   N  VAL 1  46           
SHEET    5 AA4 5 GLY 1 217  LEU 1 223 -1  O  GLN 1 221   N  LEU 1 210           
SHEET    1 AA5 4 LEU 1  68  PRO 1  70  0                                        
SHEET    2 AA5 4 ILE 1  75  GLY 1  81 -1  O  CYS 1  77   N  THR 1  69           
SHEET    3 AA5 4 ALA 1 130  ASP 1 138 -1  O  GLY 1 131   N  SER 1  80           
SHEET    4 AA5 4 GLY 1 142  VAL 1 148 -1  O  TYR 1 146   N  ILE 1 134           
SHEET    1 AA6 5 TYR 2 167  GLY 2 171  0                                        
SHEET    2 AA6 5 THR 2  45  TYR 2  51 -1  N  ILE 2  46   O  MET 2 170           
SHEET    3 AA6 5 GLY 2  54  ASP 2  60 -1  O  GLY 2  58   N  ALA 2  47           
SHEET    4 AA6 5 ILE 2 216  SER 2 222 -1  O  CYS 2 219   N  LEU 2  57           
SHEET    5 AA6 5 LYS 2 225  THR 2 233 -1  O  LYS 2 225   N  SER 2 222           
SHEET    1 AA7 5 ILE 2  77  PHE 2  79  0                                        
SHEET    2 AA7 5 ILE 2  84  GLY 2  90 -1  O  CYS 2  86   N  HIS 2  78           
SHEET    3 AA7 5 ALA 2 139  GLY 2 145 -1  O  VAL 2 142   N  CYS 2  87           
SHEET    4 AA7 5 HIS 2 152  TYR 2 157 -1  O  TYR 2 154   N  LEU 2 143           
SHEET    5 AA7 5 SER 2 161  LYS 2 164 -1  O  SER 2 161   N  TYR 2 157           
SHEET    1 AA8 6 VAL 2 254  LYS 2 258  0                                        
SHEET    2 AA8 6 ILE 3 195  LEU 3 200 -1  O  THR 3 199   N  THR 2 256           
SHEET    3 AA8 6 VAL 3 185  ILE 3 190 -1  N  VAL 3 187   O  ARG 3 198           
SHEET    4 AA8 6 CYS 3  19  ASP 3  25 -1  N  VAL 3  20   O  ILE 3 190           
SHEET    5 AA8 6 ALA 3  10  GLY 3  16 -1  N  MET 3  12   O  ALA 3  23           
SHEET    6 AA8 6 PHE 3 136  GLY 3 140 -1  O  VAL 3 137   N  ALA 3  13           
SHEET    1 AA9 2 PHE 3  28  GLY 3  29  0                                        
SHEET    2 AA9 2 MET 3  34  THR 3  36 -1  O  THR 3  36   N  PHE 3  28           
SHEET    1 AB1 5 ILE 3  42  PRO 3  44  0                                        
SHEET    2 AB1 5 LEU 3  49  LEU 3  53 -1  O  ILE 3  51   N  PHE 3  43           
SHEET    3 AB1 5 PRO 3 107  ASP 3 113 -1  O  VAL 3 108   N  GLY 3  52           
SHEET    4 AB1 5 LYS 3 118  LEU 3 124 -1  O  CYS 3 122   N  ILE 3 109           
SHEET    5 AB1 5 PRO 3 130  MET 3 131 -1  O  MET 3 131   N  SER 3 123           
SHEET    1 AB2 5 PHE 4 129  GLY 4 133  0                                        
SHEET    2 AB2 5 TYR 4   3  GLN 4   8 -1  N  LEU 4   4   O  HIS 4 132           
SHEET    3 AB2 5 VAL 4  13  SER 4  17 -1  O  LEU 4  14   N  ILE 4   7           
SHEET    4 AB2 5 SER 4 179  ASP 4 184 -1  O  SER 4 179   N  SER 4  17           
SHEET    5 AB2 5 GLY 4 187  LEU 4 191 -1  O  HIS 4 189   N  ILE 4 182           
SHEET    1 AB3 2 VAL 4  20  SER 4  23  0                                        
SHEET    2 AB3 2 GLN 4  27  HIS 4  32 -1  O  HIS 4  32   N  VAL 4  20           
SHEET    1 AB4 5 MET 4  35  PHE 4  36  0                                        
SHEET    2 AB4 5 ILE 4  42  VAL 4  47 -1  O  LEU 4  44   N  PHE 4  36           
SHEET    3 AB4 5 ASN 4 101  GLY 4 106 -1  O  LEU 4 103   N  LEU 4  45           
SHEET    4 AB4 5 ALA 4 114  MET 4 118 -1  O  MET 4 118   N  LEU 4 102           
SHEET    5 AB4 5 LEU 4 124  LYS 4 126 -1  O  ALA 4 125   N  TYR 4 117           
SHEET    1 AB5 5 THR 5 184  GLY 5 188  0                                        
SHEET    2 AB5 5 THR 5  61  LYS 5  66 -1  N  ALA 5  64   O  PHE 5 185           
SHEET    3 AB5 5 VAL 5  71  SER 5  77 -1  O  ALA 5  74   N  LEU 5  63           
SHEET    4 AB5 5 ALA 5 232  ARG 5 239 -1  O  ASN 5 234   N  ALA 5  75           
SHEET    5 AB5 5 GLY 5 242  ASP 5 249 -1  O  ILE 5 244   N  HIS 5 237           
SHEET    1 AB6 5 VAL 5  93  GLU 5  95  0                                        
SHEET    2 AB6 5 LEU 5 101  THR 5 103 -1  O  GLY 5 102   N  ILE 5  94           
SHEET    3 AB6 5 THR 5 158  TRP 5 163 -1  O  CYS 5 161   N  LEU 5 101           
SHEET    4 AB6 5 PRO 5 168  VAL 5 173 -1  O  TYR 5 171   N  ILE 5 160           
SHEET    5 AB6 5 ARG 5 179  GLY 5 182 -1  O  GLY 5 182   N  LEU 5 170           
SHEET    1 AB7 5 PHE 6 163  GLY 6 167  0                                        
SHEET    2 AB7 5 THR 6  39  ALA 6  44 -1  N  ALA 6  42   O  LYS 6 164           
SHEET    3 AB7 5 ALA 6  49  ASP 6  54 -1  O  ALA 6  52   N  LEU 6  41           
SHEET    4 AB7 5 ALA 6 220  VAL 6 226 -1  O  ARG 6 222   N  SER 6  53           
SHEET    5 AB7 5 ILE 6 231  SER 6 237 -1  O  GLU 6 234   N  ILE 6 223           
SHEET    1 AB8 2 LEU 6  57  GLU 6  59  0                                        
SHEET    2 AB8 2 SER 6  62  THR 6  65 -1  O  THR 6  65   N  LEU 6  57           
SHEET    1 AB9 5 CYS 6  71  THR 6  75  0                                        
SHEET    2 AB9 5 THR 6  78  SER 6  83 -1  O  ILE 6  80   N  TYR 6  72           
SHEET    3 AB9 5 TYR 6 135  LEU 6 141 -1  O  TYR 6 135   N  SER 6  83           
SHEET    4 AB9 5 GLY 6 147  ASP 6 153 -1  O  TYR 6 150   N  ILE 6 138           
SHEET    5 AB9 5 GLY 6 156  ARG 6 160 -1  O  GLY 6 156   N  ASP 6 153           
SHEET    1 AC1 3 THR 7  52  GLY 7  53  0                                        
SHEET    2 AC1 3 THR 7  94  ASP 7 101 -1  O  GLY 7 100   N  GLY 7  53           
SHEET    3 AC1 3 ILE 7  87  VAL 7  90 -1  N  VAL 7  90   O  THR 7  94           
SHEET    1 AC2 5 THR 7  52  GLY 7  53  0                                        
SHEET    2 AC2 5 THR 7  94  ASP 7 101 -1  O  GLY 7 100   N  GLY 7  53           
SHEET    3 AC2 5 ASN 7 153  TYR 7 160 -1  O  GLY 7 158   N  MET 7  95           
SHEET    4 AC2 5 SER 7 165  VAL 7 170 -1  O  PHE 7 166   N  GLY 7 159           
SHEET    5 AC2 5 TYR 7 177  GLU 7 178 -1  O  TYR 7 177   N  TYR 7 169           
SHEET    1 AC3 5 SER 7 181  ALA 7 183  0                                        
SHEET    2 AC3 5 VAL 7  56  LYS 7  60 -1  N  GLY 7  58   O  LEU 7 182           
SHEET    3 AC3 5 GLY 7  64  ASP 7  70 -1  O  ALA 7  68   N  LEU 7  57           
SHEET    4 AC3 5 ARG 7 231  THR 7 238 -1  O  ALA 7 235   N  ILE 7  67           
SHEET    5 AC3 5 VAL 7 242  SER 7 249 -1  O  GLU 7 245   N  ILE 7 234           
SHEET    1 AC4 2 LEU 7  72  TYR 7  75  0                                        
SHEET    2 AC4 2 LEU 7  78  ARG 7  82 -1  O  PHE 7  81   N  GLY 7  73           
SHEET    1 AC5 5 ALA A 165  ALA A 168  0                                        
SHEET    2 AC5 5 SER A  39  ARG A  43 -1  N  ALA A  41   O  THR A 166           
SHEET    3 AC5 5 CYS A  47  GLN A  53 -1  O  VAL A  49   N  VAL A  42           
SHEET    4 AC5 5 ILE A 215  THR A 221 -1  O  VAL A 220   N  ALA A  48           
SHEET    5 AC5 5 PHE A 227  ILE A 229 -1  O  ARG A 228   N  VAL A 219           
SHEET    1 AC6 5 LEU A  69  LYS A  71  0                                        
SHEET    2 AC6 5 GLY A  77  GLY A  82 -1  O  CYS A  78   N  PHE A  70           
SHEET    3 AC6 5 CYS A 136  ILE A 143 -1  O  CYS A 137   N  THR A  81           
SHEET    4 AC6 5 PRO A 149  CYS A 154 -1  O  TYR A 152   N  LEU A 140           
SHEET    5 AC6 5 TYR A 160  GLY A 162 -1  O  CYS A 161   N  LYS A 153           
SHEET    1 AC7 5 ALA B 160  MET B 163  0                                        
SHEET    2 AC7 5 SER B  35  LYS B  39 -1  N  SER B  35   O  MET B 163           
SHEET    3 AC7 5 VAL B  44  GLU B  49 -1  O  VAL B  45   N  ILE B  38           
SHEET    4 AC7 5 ILE B 208  ASN B 214 -1  O  GLU B 209   N  THR B  48           
SHEET    5 AC7 5 GLY B 217  ARG B 220 -1  O  ARG B 219   N  ILE B 212           
SHEET    1 AC8 5 GLU B  66  PRO B  67  0                                        
SHEET    2 AC8 5 ILE B  72  GLY B  78 -1  O  LEU B  74   N  GLU B  66           
SHEET    3 AC8 5 VAL B 132  GLY B 138 -1  O  SER B 133   N  SER B  77           
SHEET    4 AC8 5 PHE B 147  SER B 149 -1  O  SER B 149   N  LEU B 134           
SHEET    5 AC8 5 TYR B 155  ALA B 157 -1  O  PHE B 156   N  GLN B 148           
SHEET    1 AC9 5 ALA C 161  ILE C 164  0                                        
SHEET    2 AC9 5 CYS C  34  LEU C  38 -1  N  GLY C  36   O  THR C 162           
SHEET    3 AC9 5 VAL C  43  GLU C  48 -1  O  ALA C  46   N  LEU C  35           
SHEET    4 AC9 5 VAL C 211  THR C 217 -1  O  ALA C 214   N  LEU C  45           
SHEET    5 AC9 5 VAL C 224  VAL C 227 -1  O  VAL C 224   N  THR C 217           
SHEET    1 AD1 5 ILE C  65  LYS C  67  0                                        
SHEET    2 AD1 5 ALA C  73  ALA C  77 -1  O  CYS C  74   N  TYR C  66           
SHEET    3 AD1 5 SER C 133  GLY C 138 -1  O  ILE C 137   N  ALA C  73           
SHEET    4 AD1 5 GLN C 146  SER C 150 -1  O  GLN C 146   N  GLY C 138           
SHEET    5 AD1 5 TYR C 156  GLY C 158 -1  O  GLY C 157   N  GLN C 149           
SHEET    1 AD2 5 ALA D 158  GLY D 162  0                                        
SHEET    2 AD2 5 THR D  31  ARG D  36 -1  N  ALA D  32   O  ILE D 161           
SHEET    3 AD2 5 ILE D  40  GLU D  46 -1  O  VAL D  42   N  VAL D  35           
SHEET    4 AD2 5 ILE D 206  ARG D 212 -1  O  GLU D 207   N  VAL D  45           
SHEET    5 AD2 5 SER D 216  ILE D 219 -1  O  LYS D 218   N  VAL D 210           
SHEET    1 AD3 6 CYS D  63  ALA D  64  0                                        
SHEET    2 AD3 6 VAL D  69  ALA D  74 -1  O  MET D  71   N  CYS D  63           
SHEET    3 AD3 6 SER D 130  GLY D 135 -1  O  VAL D 134   N  CYS D  70           
SHEET    4 AD3 6 ARG D 143  ASP D 148 -1  O  TYR D 145   N  ILE D 133           
SHEET    5 AD3 6 THR D 152  TRP D 156 -1  O  HIS D 154   N  GLN D 146           
SHEET    6 AD3 6 MET E  59  GLU E  60 -1  O  GLU E  60   N  ALA D 155           
SHEET    1 AD4 5 ALA E 167  ILE E 170  0                                        
SHEET    2 AD4 5 ALA E  37  GLN E  41 -1  N  GLY E  39   O  ARG E 168           
SHEET    3 AD4 5 VAL E  46  GLU E  51 -1  O  ALA E  49   N  ILE E  38           
SHEET    4 AD4 5 ILE E 215  GLN E 221 -1  O  ALA E 218   N  LEU E  48           
SHEET    5 AD4 5 ASN E 225  MET E 228 -1  O  HIS E 227   N  THR E 219           
SHEET    1 AD5 5 ILE E  67  VAL E  68  0                                        
SHEET    2 AD5 5 ILE E  74  GLY E  80 -1  O  CYS E  76   N  VAL E  68           
SHEET    3 AD5 5 VAL E 139  GLY E 145 -1  O  GLY E 144   N  GLY E  75           
SHEET    4 AD5 5 GLN E 152  ASP E 157 -1  O  MET E 156   N  LEU E 141           
SHEET    5 AD5 5 THR E 161  CYS E 165 -1  O  VAL E 163   N  HIS E 155           
SHEET    1 AD6 5 ALA F 158  ILE F 161  0                                        
SHEET    2 AD6 5 THR F  35  LYS F  39 -1  N  THR F  35   O  ILE F 161           
SHEET    3 AD6 5 HIS F  43  LEU F  49 -1  O  VAL F  47   N  VAL F  36           
SHEET    4 AD6 5 VAL F 210  GLY F 216 -1  O  SER F 211   N  ALA F  48           
SHEET    5 AD6 5 THR F 222  ASP F 225 -1  O  TYR F 224   N  ILE F 212           
SHEET    1 AD7 6 ILE F  63  ASP F  67  0                                        
SHEET    2 AD7 6 ILE F  70  ALA F  75 -1  O  ILE F  72   N  LEU F  64           
SHEET    3 AD7 6 GLY F 131  ASP F 138 -1  O  ALA F 135   N  GLY F  71           
SHEET    4 AD7 6 GLY F 141  THR F 147 -1  O  PHE F 145   N  ILE F 134           
SHEET    5 AD7 6 PHE F 154  CYS F 156 -1  O  PHE F 154   N  GLN F 146           
SHEET    6 AD7 6 TYR G  59  GLU G  60 -1  O  GLU G  60   N  ASP F 155           
SHEET    1 AD8 5 GLY G 163  GLY G 167  0                                        
SHEET    2 AD8 5 THR G  36  CYS G  42 -1  N  ALA G  37   O  ILE G 166           
SHEET    3 AD8 5 GLY G  45  LEU G  53 -1  O  GLY G  45   N  CYS G  42           
SHEET    4 AD8 5 PHE G 210  VAL G 217 -1  O  GLU G 213   N  VAL G  50           
SHEET    5 AD8 5 GLU G 226  VAL G 228 -1  O  VAL G 228   N  LEU G 214           
SHEET    1 AD9 5 LEU G  67  VAL G  70  0                                        
SHEET    2 AD9 5 VAL G  74  GLY G  80 -1  O  MET G  76   N  PHE G  68           
SHEET    3 AD9 5 CYS G 134  SER G 142 -1  O  MET G 137   N  ALA G  77           
SHEET    4 AD9 5 GLY G 146  ASP G 153 -1  O  GLY G 146   N  SER G 142           
SHEET    5 AD9 5 VAL G 157  GLY G 160 -1  O  VAL G 157   N  ASP G 153           
SHEET    1 AE1 4 ASP H  79  LEU H  80  0                                        
SHEET    2 AE1 4 ASP I 118  SER I 124 -1  O  ASN I 119   N  ASP H  79           
SHEET    3 AE1 4 MET I 107  ILE I 116 -1  N  ILE I 116   O  HIS I 120           
SHEET    4 AE1 4 SER I 149  LEU I 152 -1  O  LEU I 152   N  SER I 108           
SHEET    1 AE2 8 ASP H  79  LEU H  80  0                                        
SHEET    2 AE2 8 ASP I 118  SER I 124 -1  O  ASN I 119   N  ASP H  79           
SHEET    3 AE2 8 MET I 107  ILE I 116 -1  N  ILE I 116   O  HIS I 120           
SHEET    4 AE2 8 LYS J  94  ASP J  98 -1  O  VAL J  96   N  MET I 107           
SHEET    5 AE2 8 LYS J  84  VAL J  89 -1  N  VAL J  85   O  VAL J  97           
SHEET    6 AE2 8 TYR J  72  ALA J  79 -1  N  VAL J  77   O  LEU J  86           
SHEET    7 AE2 8 CYS J 112  LEU J 116 -1  O  VAL J 114   N  GLY J  74           
SHEET    8 AE2 8 LEU J 123  ASN J 129 -1  O  LEU J 127   N  ARG J 113           
SHEET    1 AE3 6 GLN H 165  GLU H 167  0                                        
SHEET    2 AE3 6 CYS H 236  ILE H 241 -1  O  ARG H 239   N  GLN H 165           
SHEET    3 AE3 6 CYS H 270  ASP H 275  1  O  PHE H 273   N  ILE H 238           
SHEET    4 AE3 6 LYS H 316  ALA H 320  1  O  LEU H 318   N  ILE H 272           
SHEET    5 AE3 6 GLY H 211  LEU H 214  1  N  VAL H 212   O  VAL H 317           
SHEET    6 AE3 6 LEU H 337  ILE H 341  1  O  ILE H 341   N  LEU H 213           
SHEET    1 AE4 6 MET I 174  LYS I 178  0                                        
SHEET    2 AE4 6 THR I 246  VAL I 251 -1  O  PHE I 247   N  GLU I 177           
SHEET    3 AE4 6 SER I 280  ASP I 285  1  O  ILE I 281   N  LEU I 248           
SHEET    4 AE4 6 LYS I 326  THR I 331  1  O  ILE I 328   N  VAL I 282           
SHEET    5 AE4 6 GLY I 221  TYR I 225  1  N  VAL I 222   O  MET I 329           
SHEET    6 AE4 6 ILE I 347  GLU I 352  1  O  ILE I 351   N  ILE I 223           
SHEET    1 AE5 6 VAL J 140  GLU J 141  0                                        
SHEET    2 AE5 6 THR J 210  SER J 215 -1  O  PHE J 211   N  GLU J 141           
SHEET    3 AE5 6 SER J 244  ASP J 249  1  O  PHE J 247   N  ILE J 212           
SHEET    4 AE5 6 ILE J 289  ALA J 294  1  O  ILE J 292   N  MET J 248           
SHEET    5 AE5 6 GLY J 185  TYR J 189  1  N  VAL J 186   O  MET J 293           
SHEET    6 AE5 6 ARG J 313  GLU J 316  1  O  ILE J 315   N  LEU J 187           
SHEET    1 AE6 6 ASN K 110  ARG K 114  0                                        
SHEET    2 AE6 6 THR K 100  SER K 105 -1  N  ALA K 101   O  VAL K 113           
SHEET    3 AE6 6 LEU K  87  ASP K  97 -1  N  GLU K  94   O  ILE K 102           
SHEET    4 AE6 6 ARG L  78  CYS L  83 -1  O  VAL L  80   N  LEU K  87           
SHEET    5 AE6 6 SER K 129  LEU K 132  0                                        
SHEET    6 AE6 6 LEU K 139  VAL K 142 -1  O  ASP K 141   N  ALA K 131           
SHEET    1 AE710 ASN K 110  ARG K 114  0                                        
SHEET    2 AE710 THR K 100  SER K 105 -1  N  ALA K 101   O  VAL K 113           
SHEET    3 AE710 LEU K  87  ASP K  97 -1  N  GLU K  94   O  ILE K 102           
SHEET    4 AE710 THR L 106  LEU L 111  0                                        
SHEET    5 AE710 ARG L  97  ASP L 101 -1  N  ALA L  99   O  MET L 108           
SHEET    6 AE710 GLN L  55  GLN L  63 -1  N  ILE L  56   O  LEU L 100           
SHEET    7 AE710 PHE L  69  LYS L  72 -1  O  ILE L  70   N  LYS L  62           
SHEET    8 AE710 ARG L  78  CYS L  83 -1  O  TYR L  79   N  VAL L  71           
SHEET    9 AE710 SER K 129  LEU K 132  0                                        
SHEET   10 AE710 LEU K 139  VAL K 142 -1  O  ASP K 141   N  ALA K 131           
SHEET    1 AE8 6 THR K 155  ASP K 157  0                                        
SHEET    2 AE8 6 ALA K 226  VAL K 231 -1  O  ARG K 229   N  THR K 155           
SHEET    3 AE8 6 ALA K 260  ASP K 265  1  O  ASP K 265   N  VAL K 230           
SHEET    4 AE8 6 LYS K 306  THR K 311  1  O  ILE K 308   N  ILE K 262           
SHEET    5 AE8 6 GLY K 201  TYR K 205  1  N  VAL K 202   O  MET K 309           
SHEET    6 AE8 6 ARG K 329  ILE K 331  1  O  ILE K 331   N  LEU K 203           
SHEET    1 AE9 5 PHE L 195  VAL L 199  0                                        
SHEET    2 AE9 5 CYS L 228  ASP L 233  1  O  ILE L 229   N  LEU L 196           
SHEET    3 AE9 5 VAL L 273  THR L 279  1  O  ILE L 276   N  MET L 232           
SHEET    4 AE9 5 GLY L 169  TYR L 173  1  N  CYS L 170   O  MET L 277           
SHEET    5 AE9 5 LEU L 295  ILE L 299  1  O  ILE L 299   N  LEU L 171           
SHEET    1 AF1 5 GLN M 130  PHE M 133  0                                        
SHEET    2 AF1 5 VAL M 123  THR M 126 -1  N  THR M 126   O  GLN M 130           
SHEET    3 AF1 5 LEU M  89  VAL M  93 -1  N  ASN M  92   O  LYS M 125           
SHEET    4 AF1 5 ASP M 149  ASN M 154 -1  O  ASP M 149   N  VAL M  93           
SHEET    5 AF1 5 LEU M 159  THR M 163 -1  O  LEU M 159   N  ASN M 154           
SHEET    1 AF2 6 GLU M 176  ASP M 178  0                                        
SHEET    2 AF2 6 THR M 247  ALA M 252 -1  O  PHE M 248   N  ASP M 178           
SHEET    3 AF2 6 SER M 281  ASP M 286  1  O  PHE M 284   N  LEU M 251           
SHEET    4 AF2 6 LYS M 327  ALA M 331  1  O  ILE M 329   N  ILE M 285           
SHEET    5 AF2 6 GLY M 222  TYR M 226  1  N  VAL M 223   O  ALA M 330           
SHEET    6 AF2 6 ARG M 350  GLU M 353  1  O  ILE M 352   N  LEU M 224           
SHEET    1 AF3 2 VAL N 744  THR N 745  0                                        
SHEET    2 AF3 2 THR N 784  PRO N 785 -1  O  THR N 784   N  THR N 745           
SHEET    1 AF4 3 PHE N 875  ASP N 879  0                                        
SHEET    2 AF4 3 GLN N 801  SER N 804 -1  N  SER N 804   O  PHE N 875           
SHEET    3 AF4 3 LEU N 892  THR N 893 -1  O  THR N 893   N  LYS N 803           
SHEET    1 AF5 2 TYR N 900  PRO N 902  0                                        
SHEET    2 AF5 2 LEU N 914  ASP N 916 -1  O  LYS N 915   N  GLN N 901           
SHEET    1 AF6 6 GLN O 290  THR O 292  0                                        
SHEET    2 AF6 6 ARG O 330  THR O 334 -1  O  VAL O 331   N  LEU O 291           
SHEET    3 AF6 6 LYS O 321  ASP O 325 -1  N  LYS O 321   O  THR O 334           
SHEET    4 AF6 6 TYR P 370  THR P 374  1  O  THR P 371   N  ILE O 324           
SHEET    5 AF6 6 ILE P 412  ASN P 414 -1  O  ILE P 413   N  ILE P 373           
SHEET    6 AF6 6 LYS P 405  ASP P 407 -1  N  LYS P 405   O  ASN P 414           
SHEET    1 AF7 3 VAL Q 345  GLN Q 346  0                                        
SHEET    2 AF7 3 VAL Q 384  ILE Q 386 -1  O  LEU Q 385   N  VAL Q 345           
SHEET    3 AF7 3 ILE Q 377  ASP Q 379 -1  N  ILE Q 377   O  ILE Q 386           
SHEET    1 AF8 3 LEU R 314  THR R 315  0                                        
SHEET    2 AF8 3 ILE R 353  GLU R 355 -1  O  VAL R 354   N  LEU R 314           
SHEET    3 AF8 3 LYS R 346  ILE R 347 -1  N  LYS R 346   O  GLU R 355           
SHEET    1 AF9 3 ARG S 416  SER S 418  0                                        
SHEET    2 AF9 3 TYR S 457  SER S 460 -1  O  VAL S 458   N  ILE S 417           
SHEET    3 AF9 3 ALA S 449  ASN S 452 -1  N  SER S 450   O  GLN S 459           
SHEET    1 AG1 2 LYS T 281  LEU T 283  0                                        
SHEET    2 AG1 2 ASN T 313  TYR T 315 -1  O  ASN T 314   N  ILE T 282           
SHEET    1 AG2 7 THR U 135  ILE U 139  0                                        
SHEET    2 AG2 7 VAL U 120  ILE U 124 -1  N  ILE U 123   O  GLU U 136           
SHEET    3 AG2 7 ARG U  90  HIS U  96  1  N  TRP U  94   O  VAL U 120           
SHEET    4 AG2 7 GLY U  37  SER U  42 -1  N  GLY U  41   O  ARG U  90           
SHEET    5 AG2 7 LEU U  48  ALA U  55 -1  O  ASP U  49   N  SER U  42           
SHEET    6 AG2 7 VAL U   9  VAL U  11  1  N  VAL U  10   O  VAL U  50           
SHEET    7 AG2 7 SER U 160  GLU U 161  1  O  GLU U 161   N  VAL U  11           
SHEET    1 AG3 2 ASP U  59  GLU U  60  0                                        
SHEET    2 AG3 2 TRP U  68  PHE U  69 -1  O  PHE U  69   N  ASP U  59           
SHEET    1 AG4 7 ILE V 157  PHE V 160  0                                        
SHEET    2 AG4 7 VAL V 141  VAL V 145 -1  N  ALA V 142   O  PHE V 160           
SHEET    3 AG4 7 MET V 107  SER V 114  1  N  TRP V 111   O  VAL V 141           
SHEET    4 AG4 7 MET V  54  VAL V  62 -1  N  MET V  57   O  GLY V 110           
SHEET    5 AG4 7 THR V  66  ALA V  74 -1  O  ARG V  68   N  GLU V  60           
SHEET    6 AG4 7 GLN V  30  ILE V  33  1  N  TYR V  32   O  VAL V  67           
SHEET    7 AG4 7 THR V 204  TYR V 207  1  O  THR V 204   N  VAL V  31           
SHEET    1 AG5 6 VAL W  60  THR W  65  0                                        
SHEET    2 AG5 6 ASN W  48  THR W  53 -1  N  VAL W  49   O  THR W  65           
SHEET    3 AG5 6 GLU W   4  VAL W  10  1  N  VAL W   8   O  ILE W  52           
SHEET    4 AG5 6 LYS W 106  VAL W 113  1  O  LYS W 106   N  SER W   5           
SHEET    5 AG5 6 ASN W 137  ASN W 142  1  O  ILE W 141   N  ALA W 111           
SHEET    6 AG5 6 HIS W 169  THR W 172  1  O  VAL W 171   N  ASN W 142           
CISPEP   1 THR I  105    PRO I  106          0        -7.19                     
CISPEP   2 ALA I  278    PRO I  279          0       -11.59                     
CISPEP   3 ALA J  242    PRO J  243          0         0.32                     
CISPEP   4 ILE K   85    PRO K   86          0       -17.53                     
CISPEP   5 ALA K  258    PRO K  259          0        -1.30                     
CISPEP   6 GLN L  226    PRO L  227          0         0.93                     
CISPEP   7 LEU M   86    PRO M   87          0        11.56                     
CISPEP   8 ALA M  279    PRO M  280          0        -1.23                     
CISPEP   9 LEU P  455    GLN P  456          0       -10.30                     
CISPEP  10 MET T  348    ILE T  349          0        -0.81                     
CISPEP  11 GLY U   98    PRO U   99          0        -2.27                     
CISPEP  12 VAL V   49    PRO V   50          0         2.22                     
CISPEP  13 LEU W   22    PRO W   23          0       -15.43                     
CRYST1    1.000    1.000    1.000  90.00  90.00  90.00 P 1           1          
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      1.000000  0.000000  0.000000        0.00000                         
SCALE2      0.000000  1.000000  0.000000        0.00000                         
SCALE3      0.000000  0.000000  1.000000        0.00000                         
(ATOM LINES ARE NOT SHOWN.)
END                                                                             
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