GenomeNet

Database: PDB
Entry: 5MPS
LinkDB: 5MPS
Original site: 5MPS 
HEADER    SPLICING                                18-DEC-16   5MPS              
TITLE     STRUCTURE OF A SPLICEOSOME REMODELED FOR EXON LIGATION                
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: YEAST UBC4 GENE FOR UBIQUITIN-CONJUGATING ENZYME;          
COMPND   3 CHAIN: I;                                                            
COMPND   4 ENGINEERED: YES;                                                     
COMPND   5 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE UBC4 PRE-MRNA INTRON, IN     
COMPND   6 VITRO TRANSCRIBED.;                                                  
COMPND   7 MOL_ID: 2;                                                           
COMPND   8 MOLECULE: UBC4 GENE EXON;                                            
COMPND   9 CHAIN: E;                                                            
COMPND  10 ENGINEERED: YES;                                                     
COMPND  11 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE UBC4 PRE-MRNA EXON, IN VITRO 
COMPND  12 TRANSCRIBED.;                                                        
COMPND  13 MOL_ID: 3;                                                           
COMPND  14 MOLECULE: U2 SNRNA;                                                  
COMPND  15 CHAIN: 2;                                                            
COMPND  16 ENGINEERED: YES;                                                     
COMPND  17 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE U2 SNRNA;                    
COMPND  18 MOL_ID: 4;                                                           
COMPND  19 MOLECULE: SACCHAROMYCES CEREVISIAE STRAIN T.52_2H CHROMOSOME XII     
COMPND  20 SEQUENCE;                                                            
COMPND  21 CHAIN: 6;                                                            
COMPND  22 ENGINEERED: YES;                                                     
COMPND  23 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE U6 SNRNA;                    
COMPND  24 MOL_ID: 5;                                                           
COMPND  25 MOLECULE: U5 SNRNA;                                                  
COMPND  26 CHAIN: 5;                                                            
COMPND  27 ENGINEERED: YES;                                                     
COMPND  28 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE U5 SNRNA;                    
COMPND  29 MOL_ID: 6;                                                           
COMPND  30 MOLECULE: PRE-MRNA-SPLICING FACTOR 8;                                
COMPND  31 CHAIN: A;                                                            
COMPND  32 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE PRP8 PROTEIN;                
COMPND  33 MOL_ID: 7;                                                           
COMPND  34 MOLECULE: PRE-MRNA-SPLICING FACTOR SNU114;                           
COMPND  35 CHAIN: C;                                                            
COMPND  36 SYNONYM: 114 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT,GROWTH 
COMPND  37 INHIBITORY PROTEIN 10;                                               
COMPND  38 OTHER_DETAILS: C SNU114 PROTEIN;                                     
COMPND  39 MOL_ID: 8;                                                           
COMPND  40 MOLECULE: PRE-MRNA-SPLICING FACTOR CWC22;                            
COMPND  41 CHAIN: H;                                                            
COMPND  42 SYNONYM: COMPLEXED WITH CEF1 PROTEIN 22;                             
COMPND  43 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE CWC22 PROTEIN;               
COMPND  44 MOL_ID: 9;                                                           
COMPND  45 MOLECULE: PRE-MRNA-SPLICING FACTOR PRP46;                            
COMPND  46 CHAIN: J;                                                            
COMPND  47 SYNONYM: COMPLEXED WITH CEF1 PROTEIN 1,PRP NINETEEN-ASSOCIATED       
COMPND  48 COMPLEX PROTEIN 50,PRP19-ASSOCIATED COMPLEX PROTEIN 50,PRE-MRNA-     
COMPND  49 PROCESSING PROTEIN 46;                                               
COMPND  50 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE PRP46 PROTEIN;               
COMPND  51 MOL_ID: 10;                                                          
COMPND  52 MOLECULE: PRE-MRNA-PROCESSING PROTEIN 45;                            
COMPND  53 CHAIN: K;                                                            
COMPND  54 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE PRP45 PROTEIN;               
COMPND  55 MOL_ID: 11;                                                          
COMPND  56 MOLECULE: PRE-MRNA-SPLICING FACTOR BUD31;                            
COMPND  57 CHAIN: L;                                                            
COMPND  58 SYNONYM: BUD SITE SELECTION PROTEIN 31,COMPLEXED WITH CEF1 PROTEIN   
COMPND  59 14;                                                                  
COMPND  60 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE BUD31 PROTEIN;               
COMPND  61 MOL_ID: 12;                                                          
COMPND  62 MOLECULE: PRE-MRNA-SPLICING FACTOR CWC2;                             
COMPND  63 CHAIN: M;                                                            
COMPND  64 SYNONYM: COMPLEXED WITH CEF1 PROTEIN 2,PRP19-ASSOCIATED COMPLEX      
COMPND  65 PROTEIN 40,SYNTHETIC LETHAL WITH CLF1 PROTEIN 3;                     
COMPND  66 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE CWC2 PROTEIN;                
COMPND  67 MOL_ID: 13;                                                          
COMPND  68 MOLECULE: PRE-MRNA-SPLICING FACTOR SLT11;                            
COMPND  69 CHAIN: N;                                                            
COMPND  70 SYNONYM: EXTRACELLULAR MUTANT PROTEIN 2,SYNTHETIC LETHALITY WITH U2  
COMPND  71 PROTEIN 11;                                                          
COMPND  72 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE ECM2 PROTEIN;                
COMPND  73 MOL_ID: 14;                                                          
COMPND  74 MOLECULE: PRE-MRNA-SPLICING FACTOR CEF1;                             
COMPND  75 CHAIN: O;                                                            
COMPND  76 SYNONYM: PRP NINETEEN-ASSOCIATED COMPLEX PROTEIN 85,PRP19-ASSOCIATED 
COMPND  77 COMPLEX PROTEIN 85;                                                  
COMPND  78 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE CEF1 PROTEIN;                
COMPND  79 MOL_ID: 15;                                                          
COMPND  80 MOLECULE: PRE-MRNA-SPLICING FACTOR CWC15;                            
COMPND  81 CHAIN: P;                                                            
COMPND  82 SYNONYM: COMPLEXED WITH CEF1 PROTEIN 15;                             
COMPND  83 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE CWC15 PROTEIN;               
COMPND  84 MOL_ID: 16;                                                          
COMPND  85 MOLECULE: PRE-MRNA-SPLICING FACTOR CWC21;                            
COMPND  86 CHAIN: R;                                                            
COMPND  87 SYNONYM: COMPLEXED WITH CEF1 PROTEIN 21;                             
COMPND  88 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE CWC21 PROTEIN;               
COMPND  89 MOL_ID: 17;                                                          
COMPND  90 MOLECULE: PRE-MRNA-SPLICING FACTOR CLF1;                             
COMPND  91 CHAIN: S;                                                            
COMPND  92 SYNONYM: CROOKED NECK-LIKE FACTOR 1,PRP19-ASSOCIATED COMPLEX PROTEIN 
COMPND  93 77,SYNTHETIC LETHAL WITH CDC40 PROTEIN 3;                            
COMPND  94 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE CLF1 PROTEIN;                
COMPND  95 MOL_ID: 18;                                                          
COMPND  96 MOLECULE: PRE-MRNA-SPLICING FACTOR SYF1;                             
COMPND  97 CHAIN: T;                                                            
COMPND  98 SYNONYM: PRP19-ASSOCIATED COMPLEX PROTEIN 90,SYNTHETIC LETHAL WITH   
COMPND  99 CDC40 PROTEIN 1;                                                     
COMPND 100 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE SYF1 PROTEIN;                
COMPND 101 MOL_ID: 19;                                                          
COMPND 102 MOLECULE: PRE-MRNA-SPLICING FACTOR 18;                               
COMPND 103 CHAIN: a;                                                            
COMPND 104 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE PRP18 PROTEIN;               
COMPND 105 MOL_ID: 20;                                                          
COMPND 106 MOLECULE: PRE-MRNA-SPLICING FACTOR SLU7;                             
COMPND 107 CHAIN: c;                                                            
COMPND 108 SYNONYM: SYNTHETIC LETHAL WITH U2 SNRNA PROTEIN 17,SYNTHETIC LETHAL  
COMPND 109 WITH U5 SNRNA PROTEIN 7;                                             
COMPND 110 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE SLU7 PROTEIN;                
COMPND 111 MOL_ID: 21;                                                          
COMPND 112 MOLECULE: PRE-MRNA-PROCESSING FACTOR 17;                             
COMPND 113 CHAIN: o;                                                            
COMPND 114 SYNONYM: CELL DIVISION CONTROL PROTEIN 40;                           
COMPND 115 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE PRP17 PROTEIN;               
COMPND 116 MOL_ID: 22;                                                          
COMPND 117 MOLECULE: UNKNOWN;                                                   
COMPND 118 CHAIN: X;                                                            
COMPND 119 OTHER_DETAILS: UNKNOWN PROTEIN HELICES WITHIN C-STAR COMPLEX;        
COMPND 120 MOL_ID: 23;                                                          
COMPND 121 MOLECULE: PRE-MRNA-SPLICING FACTOR SYF2;                             
COMPND 122 CHAIN: y;                                                            
COMPND 123 SYNONYM: PRP19 COMPLEX PROTEIN 31,SYNTHETIC LETHAL WITH CDC40 PROTEIN
COMPND 124 2;                                                                   
COMPND 125 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE SYF2 PROTEIN;                
COMPND 126 MOL_ID: 24;                                                          
COMPND 127 MOLECULE: SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B;      
COMPND 128 CHAIN: b;                                                            
COMPND 129 SYNONYM: SNRNP-B,SM PROTEIN B,SMB;                                   
COMPND 130 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE SMB PROTEIN;                 
COMPND 131 MOL_ID: 25;                                                          
COMPND 132 MOLECULE: SMALL NUCLEAR RIBONUCLEOPROTEIN SM D3;                     
COMPND 133 CHAIN: d;                                                            
COMPND 134 SYNONYM: SM-D3,SNRNP CORE PROTEIN D3;                                
COMPND 135 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE SMD3 PROTEIN;                
COMPND 136 MOL_ID: 26;                                                          
COMPND 137 MOLECULE: SMALL NUCLEAR RIBONUCLEOPROTEIN E;                         
COMPND 138 CHAIN: e;                                                            
COMPND 139 SYNONYM: SNRNP-E,SM PROTEIN E,SME;                                   
COMPND 140 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE SME PROTEIN;                 
COMPND 141 MOL_ID: 27;                                                          
COMPND 142 MOLECULE: SMALL NUCLEAR RIBONUCLEOPROTEIN F;                         
COMPND 143 CHAIN: f;                                                            
COMPND 144 SYNONYM: SNRNP-F,SM PROTEIN F,SMF;                                   
COMPND 145 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE SMF PROTEIN;                 
COMPND 146 MOL_ID: 28;                                                          
COMPND 147 MOLECULE: SMALL NUCLEAR RIBONUCLEOPROTEIN G;                         
COMPND 148 CHAIN: g;                                                            
COMPND 149 SYNONYM: SNRNP-G,SM PROTEIN G,SMG;                                   
COMPND 150 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE SMG PROTEIN;                 
COMPND 151 MOL_ID: 29;                                                          
COMPND 152 MOLECULE: SMALL NUCLEAR RIBONUCLEOPROTEIN SM D1;                     
COMPND 153 CHAIN: h;                                                            
COMPND 154 SYNONYM: SM-D1,SNRNP CORE PROTEIN D1;                                
COMPND 155 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE SMD1 PROTEIN;                
COMPND 156 MOL_ID: 30;                                                          
COMPND 157 MOLECULE: SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2;                     
COMPND 158 CHAIN: j;                                                            
COMPND 159 SYNONYM: SM-D2,SNRNP CORE PROTEIN D2;                                
COMPND 160 OTHER_DETAILS: SACCHAROMYCES CEREVISIAE SMD2 PROTEIN                 
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE   3 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE   4 ORGANISM_TAXID: 4932;                                                
SOURCE   5 EXPRESSION_SYSTEM: IN VITRO TRANSCRIPTION VECTOR PT7-FLUC(DELTAI);   
SOURCE   6 EXPRESSION_SYSTEM_TAXID: 905932;                                     
SOURCE   7 MOL_ID: 2;                                                           
SOURCE   8 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE   9 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  10 ORGANISM_TAXID: 4932;                                                
SOURCE  11 GENE: UBC4;                                                          
SOURCE  12 EXPRESSION_SYSTEM: IN VITRO TRANSCRIPTION VECTOR PT7-FLUC(DELTAI);   
SOURCE  13 EXPRESSION_SYSTEM_TAXID: 905932;                                     
SOURCE  14 MOL_ID: 3;                                                           
SOURCE  15 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  16 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  17 ORGANISM_TAXID: 4932;                                                
SOURCE  18 EXPRESSION_SYSTEM: SACCHAROMYCES CEREVISIAE;                         
SOURCE  19 EXPRESSION_SYSTEM_COMMON: BAKER'S YEAST;                             
SOURCE  20 EXPRESSION_SYSTEM_TAXID: 4932;                                       
SOURCE  21 MOL_ID: 4;                                                           
SOURCE  22 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  23 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  24 ORGANISM_TAXID: 4932;                                                
SOURCE  25 EXPRESSION_SYSTEM: SACCHAROMYCES CEREVISIAE;                         
SOURCE  26 EXPRESSION_SYSTEM_COMMON: BAKER'S YEAST;                             
SOURCE  27 EXPRESSION_SYSTEM_TAXID: 4932;                                       
SOURCE  28 MOL_ID: 5;                                                           
SOURCE  29 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  30 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  31 ORGANISM_TAXID: 4932;                                                
SOURCE  32 EXPRESSION_SYSTEM: SACCHAROMYCES CEREVISIAE;                         
SOURCE  33 EXPRESSION_SYSTEM_COMMON: BAKER'S YEAST;                             
SOURCE  34 EXPRESSION_SYSTEM_TAXID: 4932;                                       
SOURCE  35 MOL_ID: 6;                                                           
SOURCE  36 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  37 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  38 ORGANISM_TAXID: 4932;                                                
SOURCE  39 MOL_ID: 7;                                                           
SOURCE  40 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  41 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  42 ORGANISM_TAXID: 4932;                                                
SOURCE  43 MOL_ID: 8;                                                           
SOURCE  44 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  45 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  46 ORGANISM_TAXID: 4932;                                                
SOURCE  47 MOL_ID: 9;                                                           
SOURCE  48 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  49 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  50 ORGANISM_TAXID: 4932;                                                
SOURCE  51 MOL_ID: 10;                                                          
SOURCE  52 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  53 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  54 ORGANISM_TAXID: 4932;                                                
SOURCE  55 MOL_ID: 11;                                                          
SOURCE  56 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  57 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  58 ORGANISM_TAXID: 4932;                                                
SOURCE  59 MOL_ID: 12;                                                          
SOURCE  60 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  61 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  62 ORGANISM_TAXID: 4932;                                                
SOURCE  63 MOL_ID: 13;                                                          
SOURCE  64 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  65 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  66 ORGANISM_TAXID: 4932;                                                
SOURCE  67 MOL_ID: 14;                                                          
SOURCE  68 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  69 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  70 ORGANISM_TAXID: 4932;                                                
SOURCE  71 MOL_ID: 15;                                                          
SOURCE  72 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  73 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  74 ORGANISM_TAXID: 4932;                                                
SOURCE  75 MOL_ID: 16;                                                          
SOURCE  76 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  77 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  78 ORGANISM_TAXID: 4932;                                                
SOURCE  79 MOL_ID: 17;                                                          
SOURCE  80 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  81 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  82 ORGANISM_TAXID: 4932;                                                
SOURCE  83 MOL_ID: 18;                                                          
SOURCE  84 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  85 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  86 ORGANISM_TAXID: 4932;                                                
SOURCE  87 MOL_ID: 19;                                                          
SOURCE  88 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  89 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  90 ORGANISM_TAXID: 4932;                                                
SOURCE  91 MOL_ID: 20;                                                          
SOURCE  92 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  93 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  94 ORGANISM_TAXID: 4932;                                                
SOURCE  95 MOL_ID: 21;                                                          
SOURCE  96 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE  97 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE  98 ORGANISM_TAXID: 4932;                                                
SOURCE  99 MOL_ID: 22;                                                          
SOURCE 100 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE 101 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE 102 ORGANISM_TAXID: 4932;                                                
SOURCE 103 MOL_ID: 23;                                                          
SOURCE 104 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE 105 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE 106 ORGANISM_TAXID: 4932;                                                
SOURCE 107 MOL_ID: 24;                                                          
SOURCE 108 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE 109 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE 110 ORGANISM_TAXID: 4932;                                                
SOURCE 111 MOL_ID: 25;                                                          
SOURCE 112 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE 113 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE 114 ORGANISM_TAXID: 4932;                                                
SOURCE 115 MOL_ID: 26;                                                          
SOURCE 116 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE 117 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE 118 ORGANISM_TAXID: 4932;                                                
SOURCE 119 MOL_ID: 27;                                                          
SOURCE 120 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE 121 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE 122 ORGANISM_TAXID: 4932;                                                
SOURCE 123 MOL_ID: 28;                                                          
SOURCE 124 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE 125 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE 126 ORGANISM_TAXID: 4932;                                                
SOURCE 127 MOL_ID: 29;                                                          
SOURCE 128 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE 129 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE 130 ORGANISM_TAXID: 4932;                                                
SOURCE 131 MOL_ID: 30;                                                          
SOURCE 132 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;                       
SOURCE 133 ORGANISM_COMMON: BAKER'S YEAST;                                      
SOURCE 134 ORGANISM_TAXID: 4932                                                 
KEYWDS    PRE-MRNA SPLICING, TRANS-ESTERIFICATION, LARIAT INTERMEDIATE, COMPLEX 
KEYWDS   2 C-STAR, SPLICING                                                     
EXPDTA    ELECTRON MICROSCOPY                                                   
AUTHOR    S.M.FICA,C.OUBRIDGE,W.P.GALEJ,M.E.WILKINSON,A.J.NEWMAN,X.-C.BAI,      
AUTHOR   2 K.NAGAI                                                              
REVDAT   5   17-OCT-18 5MPS    1       REMARK                                   
REVDAT   4   30-AUG-17 5MPS    1       REMARK                                   
REVDAT   3   05-JUL-17 5MPS    1       HEADER                                   
REVDAT   2   01-MAR-17 5MPS    1       JRNL                                     
REVDAT   1   18-JAN-17 5MPS    0                                                
JRNL        AUTH   S.M.FICA,C.OUBRIDGE,W.P.GALEJ,M.E.WILKINSON,X.C.BAI,         
JRNL        AUTH 2 A.J.NEWMAN,K.NAGAI                                           
JRNL        TITL   STRUCTURE OF A SPLICEOSOME REMODELLED FOR EXON LIGATION.     
JRNL        REF    NATURE                        V. 542   377 2017              
JRNL        REFN                   ESSN 1476-4687                               
JRNL        PMID   28076345                                                     
JRNL        DOI    10.1038/NATURE21078                                          
REMARK   1                                                                      
REMARK   1 REFERENCE 1                                                          
REMARK   1  AUTH   J.HANG,R.WAN,C.YAN,Y.SHI                                     
REMARK   1  TITL   STRUCTURAL BASIS OF PRE-MRNA SPLICING.                       
REMARK   1  REF    SCIENCE                       V. 349  1191 2015              
REMARK   1  REFN                   ESSN 1095-9203                               
REMARK   1  PMID   26292705                                                     
REMARK   1  DOI    10.1126/SCIENCE.AAC8159                                      
REMARK   1 REFERENCE 2                                                          
REMARK   1  AUTH   T.H.NGUYEN,W.P.GALEJ,X.C.BAI,C.G.SAVVA,A.J.NEWMAN,           
REMARK   1  AUTH 2 S.H.SCHERES,K.NAGAI                                          
REMARK   1  TITL   THE ARCHITECTURE OF THE SPLICEOSOMAL U4/U6.U5 TRI-SNRNP.     
REMARK   1  REF    NATURE                        V. 523    47 2015              
REMARK   1  REFN                   ESSN 1476-4687                               
REMARK   1  PMID   26106855                                                     
REMARK   1  DOI    10.1038/NATURE14548                                          
REMARK   1 REFERENCE 3                                                          
REMARK   1  AUTH   T.H.NGUYEN,W.P.GALEJ,X.C.BAI,C.OUBRIDGE,A.J.NEWMAN,          
REMARK   1  AUTH 2 S.H.SCHERES,K.NAGAI                                          
REMARK   1  TITL   CRYO-EM STRUCTURE OF THE YEAST U4/U6.U5 TRI-SNRNP AT 3.7 A   
REMARK   1  TITL 2 RESOLUTION.                                                  
REMARK   1  REF    NATURE                        V. 530   298 2016              
REMARK   1  REFN                   ESSN 1476-4687                               
REMARK   1  PMID   26829225                                                     
REMARK   1  DOI    10.1038/NATURE16940                                          
REMARK   1 REFERENCE 4                                                          
REMARK   1  AUTH   W.P.GALEJ,M.E.WILKINSON,S.M.FICA,C.OUBRIDGE,A.J.NEWMAN,      
REMARK   1  AUTH 2 K.NAGAI                                                      
REMARK   1  TITL   CRYO-EM STRUCTURE OF THE SPLICEOSOME IMMEDIATELY AFTER       
REMARK   1  TITL 2 BRANCHING.                                                   
REMARK   1  REF    NATURE                        V. 537   197 2016              
REMARK   1  REFN                   ESSN 1476-4687                               
REMARK   1  PMID   27459055                                                     
REMARK   1  DOI    10.1038/NATURE19316                                          
REMARK   2                                                                      
REMARK   2 RESOLUTION.    3.85 ANGSTROMS.                                       
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   SOFTWARE PACKAGES      : RELION, CTFFIND, COOT, RELION, RELION,    
REMARK   3                            RELION, RELION, REFMAC                    
REMARK   3   RECONSTRUCTION SCHEMA  : NULL                                      
REMARK   3                                                                      
REMARK   3 EM MAP-MODEL FITTING AND REFINEMENT                                  
REMARK   3   PDB ENTRY                    : NULL                                
REMARK   3   REFINEMENT SPACE             : RECIPROCAL                          
REMARK   3   REFINEMENT PROTOCOL          : FLEXIBLE FIT                        
REMARK   3   REFINEMENT TARGET            : FOURIER SHELL CORRELATION           
REMARK   3   OVERALL ANISOTROPIC B VALUE  : 330.000                             
REMARK   3                                                                      
REMARK   3 FITTING PROCEDURE : USED SECONDARY STRUCTURE RESTRAINTS GENERATED    
REMARK   3  IN PROSMART AND LIBG.                                               
REMARK   3                                                                      
REMARK   3 EM IMAGE RECONSTRUCTION STATISTICS                                   
REMARK   3   NOMINAL PIXEL SIZE (ANGSTROMS)    : NULL                           
REMARK   3   ACTUAL PIXEL SIZE  (ANGSTROMS)    : NULL                           
REMARK   3   EFFECTIVE RESOLUTION (ANGSTROMS)  : 3.850                          
REMARK   3   NUMBER OF PARTICLES               : 65824                          
REMARK   3   CTF CORRECTION METHOD             : PHASE FLIPPING AND AMPLITUDE   
REMARK   3                                       CORRECTION                     
REMARK   3                                                                      
REMARK   3 EM RECONSTRUCTION MAGNIFICATION CALIBRATION: NULL                    
REMARK   3                                                                      
REMARK   3 OTHER DETAILS: NULL                                                  
REMARK   4                                                                      
REMARK   4 5MPS COMPLIES WITH FORMAT V. 3.30, 13-JUL-11                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBE ON 19-DEC-16.                  
REMARK 100 THE DEPOSITION ID IS D_1200002805.                                   
REMARK 245                                                                      
REMARK 245 EXPERIMENTAL DETAILS                                                 
REMARK 245   RECONSTRUCTION METHOD          : SINGLE PARTICLE                   
REMARK 245   SPECIMEN TYPE                  : NULL                              
REMARK 245                                                                      
REMARK 245 ELECTRON MICROSCOPE SAMPLE                                           
REMARK 245   SAMPLE TYPE                    : PARTICLE                          
REMARK 245   PARTICLE TYPE                  : POINT                             
REMARK 245   NAME OF SAMPLE                 : SACCHAROMYCES CEREVISIAE          
REMARK 245                                    SPLICEOSOME. COMPLEX C JUST       
REMARK 245                                    AFTER PRP16-MEDIATED REMODELING   
REMARK 245   SAMPLE CONCENTRATION (MG ML-1) : 0.30                              
REMARK 245   SAMPLE SUPPORT DETAILS         : NULL                              
REMARK 245   SAMPLE VITRIFICATION DETAILS   : 3.5 MICROLITRES SAMPLE WERE       
REMARK 245                                    APPLIED TO THE GRID, LEFT FOR     
REMARK 245                                    25 SECONDS AND THEN BLOTTED FOR   
REMARK 245                                    3.0-3.5 SECONDS BEFORE PLUNGING.  
REMARK 245   SAMPLE BUFFER                  : NULL                              
REMARK 245   PH                             : 7.90                              
REMARK 245   SAMPLE DETAILS                 : SPLICING EXTRACT WAS PREPARED     
REMARK 245  FROM SLU7-TAPS YEAST STRAINS. AN IN VITRO TRANSCRIBED YEAST UBC4    
REMARK 245  PRE-MRNA SUBSTRATE (WITH 2 X MS2 BACTERIOPHAGE COAT PROTEIN-        
REMARK 245  BINDING STEM LOOPS AT THE 5' END AND WITH A 2'-DEOXY                
REMARK 245  SUBSTITUTION AT THE 3'-SPLICE SITE SEQUENCE UAG SEQUENCE (UA-2'     
REMARK 245  DG) WAS PRE-BOUND TO AN MS2-MALTOSE BINDING PROTEIN FUSION          
REMARK 245  PROTEIN. THIS SUBSTRATE-PROTEIN COMPLEX WAS ADDED TO THE            
REMARK 245  SPLICING EXTRACT. THE SPLICING REACTION PROCEEDED THROUGH THE       
REMARK 245  FIRST STEP BUT THE SECOND STEP WAS BLOCKED BY THE DEOXY             
REMARK 245  SUBSTITUTION. SUBSTRATE-BOUND SPLICEOSOMES FROM THE SPLICING        
REMARK 245  EXTRACT WERE PURIFIED ON AMYLOSE RESIN AND ELUTED WITH MALTOSE.     
REMARK 245  SUBSEQUENTLY THE SPLICEOSOMES WERE CAPTURED ON STREPTACTIN RESIN    
REMARK 245  AND ELUTED WITH DESTHIOBIOTIN. PURIFIED SPLICEOSOMES WERE           
REMARK 245  CONCENTRATED IN 20 MM HEPES KOH PH 7.9, 100 MM KCL, 0.25 MM EDTA.   
REMARK 245                                                                      
REMARK 245 DATA ACQUISITION                                                     
REMARK 245   DATE OF EXPERIMENT                : NULL                           
REMARK 245   NUMBER OF MICROGRAPHS-IMAGES      : 3596                           
REMARK 245   TEMPERATURE (KELVIN)              : NULL                           
REMARK 245   MICROSCOPE MODEL                  : FEI TITAN KRIOS                
REMARK 245   DETECTOR TYPE                     : GATAN K2 SUMMIT (4K X 4K)      
REMARK 245   MINIMUM DEFOCUS (NM)              : 500.00                         
REMARK 245   MAXIMUM DEFOCUS (NM)              : 4500.00                        
REMARK 245   MINIMUM TILT ANGLE (DEGREES)      : NULL                           
REMARK 245   MAXIMUM TILT ANGLE (DEGREES)      : NULL                           
REMARK 245   NOMINAL CS                        : NULL                           
REMARK 245   IMAGING MODE                      : BRIGHT FIELD                   
REMARK 245   ELECTRON DOSE (ELECTRONS NM**-2)  : 2.00                           
REMARK 245   ILLUMINATION MODE                 : FLOOD BEAM                     
REMARK 245   NOMINAL MAGNIFICATION             : 81000                          
REMARK 245   CALIBRATED MAGNIFICATION          : NULL                           
REMARK 245   SOURCE                            : FIELD EMISSION GUN             
REMARK 245   ACCELERATION VOLTAGE (KV)         : 300                            
REMARK 245   IMAGING DETAILS                   : GIF QUANTUM ENERGY FILTER,     
REMARK 245  20 EV SLIT WIDTH                                                    
REMARK 247                                                                      
REMARK 247 ELECTRON MICROSCOPY                                                  
REMARK 247  THE COORDINATES IN THIS ENTRY WERE GENERATED FROM ELECTRON          
REMARK 247  MICROSCOPY DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE              
REMARK 247  THAT CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES           
REMARK 247  ON THESE RECORDS ARE MEANINGLESS EXCEPT FOR THE CALCULATION         
REMARK 247  OF THE STRUCTURE FACTORS.                                           
REMARK 300                                                                      
REMARK 300 BIOMOLECULE: 1                                                       
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM                
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN                  
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON               
REMARK 300 BURIED SURFACE AREA.                                                 
REMARK 350                                                                      
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN           
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE                
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS          
REMARK 350 GIVEN BELOW.  BOTH NON-CRYSTALLOGRAPHIC AND                          
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.                               
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 1                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: 30-MERIC                          
REMARK 350 APPLY THE FOLLOWING TO CHAINS: I, E, 2, 6, 5, A, C, H, J, K,         
REMARK 350                    AND CHAINS: L, M, N, O, P, R, S, T, a,            
REMARK 350                    AND CHAINS: c, o, X, y, b, d, e, f, g, h,         
REMARK 350                    AND CHAINS: j                                     
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 465                                                                      
REMARK 465 MISSING RESIDUES                                                     
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE                       
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)                
REMARK 465                                                                      
REMARK 465   M RES C SSSEQI                                                     
REMARK 465       G I    17                                                      
REMARK 465       G I    18                                                      
REMARK 465       C I    19                                                      
REMARK 465       C I    20                                                      
REMARK 465       A I    21                                                      
REMARK 465       C I    22                                                      
REMARK 465       G I    23                                                      
REMARK 465       U I    24                                                      
REMARK 465       U I    25                                                      
REMARK 465       U I    26                                                      
REMARK 465       C I    27                                                      
REMARK 465       A I    28                                                      
REMARK 465       A I    29                                                      
REMARK 465       A I    30                                                      
REMARK 465       U I    31                                                      
REMARK 465       G I    32                                                      
REMARK 465       C I    33                                                      
REMARK 465       G I    34                                                      
REMARK 465       U I    35                                                      
REMARK 465       G I    36                                                      
REMARK 465       C I    37                                                      
REMARK 465       U I    38                                                      
REMARK 465       U I    39                                                      
REMARK 465       U I    40                                                      
REMARK 465       U I    41                                                      
REMARK 465       U I    42                                                      
REMARK 465       U I    43                                                      
REMARK 465       U I    44                                                      
REMARK 465       U I    45                                                      
REMARK 465       U I    46                                                      
REMARK 465       A I    47                                                      
REMARK 465       A I    48                                                      
REMARK 465       A I    49                                                      
REMARK 465       A I    50                                                      
REMARK 465       C I    51                                                      
REMARK 465       U I    52                                                      
REMARK 465       U I    53                                                      
REMARK 465       A I    54                                                      
REMARK 465       U I    55                                                      
REMARK 465       A I    74                                                      
REMARK 465       A I    75                                                      
REMARK 465       U I    76                                                      
REMARK 465       C I    77                                                      
REMARK 465       A I    78                                                      
REMARK 465       A I    79                                                      
REMARK 465       C I    80                                                      
REMARK 465       A I    81                                                      
REMARK 465       U I    82                                                      
REMARK 465       G I    83                                                      
REMARK 465       C I    84                                                      
REMARK 465       U I    85                                                      
REMARK 465       A I    86                                                      
REMARK 465       U I    87                                                      
REMARK 465       U I    88                                                      
REMARK 465       G I    89                                                      
REMARK 465       A I    90                                                      
REMARK 465       A I    91                                                      
REMARK 465       C I    92                                                      
REMARK 465       U I    93                                                      
REMARK 465       A I    94                                                      
REMARK 465       G I    95                                                      
REMARK 465       G E   -20                                                      
REMARK 465       A E   -19                                                      
REMARK 465       A E   -18                                                      
REMARK 465       G E   -17                                                      
REMARK 465       U 2    50                                                      
REMARK 465       C 2    51                                                      
REMARK 465       A 2    52                                                      
REMARK 465       G 2    53                                                      
REMARK 465       U 2    54                                                      
REMARK 465       G 2    55                                                      
REMARK 465       U 2    56                                                      
REMARK 465       A 2    57                                                      
REMARK 465       A 2    58                                                      
REMARK 465       C 2    59                                                      
REMARK 465       A 2    60                                                      
REMARK 465       A 2    61                                                      
REMARK 465       C 2    62                                                      
REMARK 465       U 2    63                                                      
REMARK 465       G 2    64                                                      
REMARK 465       A 2    65                                                      
REMARK 465       A 2    66                                                      
REMARK 465       A 2    67                                                      
REMARK 465       U 2    68                                                      
REMARK 465       G 2    69                                                      
REMARK 465       A 2    70                                                      
REMARK 465       C 2    71                                                      
REMARK 465       C 2    72                                                      
REMARK 465       U 2    73                                                      
REMARK 465       C 2    74                                                      
REMARK 465       A 2    75                                                      
REMARK 465       A 2    76                                                      
REMARK 465       U 2    77                                                      
REMARK 465       G 2    78                                                      
REMARK 465       A 2    79                                                      
REMARK 465       G 2    80                                                      
REMARK 465       G 2    81                                                      
REMARK 465       C 2    82                                                      
REMARK 465       U 2    83                                                      
REMARK 465       C 2    84                                                      
REMARK 465       A 2    85                                                      
REMARK 465       U 2    86                                                      
REMARK 465       U 2    87                                                      
REMARK 465       A 2    88                                                      
REMARK 465       C 2    89                                                      
REMARK 465       C 2    90                                                      
REMARK 465       U 2    91                                                      
REMARK 465       U 2    92                                                      
REMARK 465       U 2    93                                                      
REMARK 465       U 2    94                                                      
REMARK 465       A 2    95                                                      
REMARK 465       A 2    96                                                      
REMARK 465       U 2    97                                                      
REMARK 465       U 2    98                                                      
REMARK 465       U 2    99                                                      
REMARK 465       G 2   100                                                      
REMARK 465       U 2   101                                                      
REMARK 465       U 2   102                                                      
REMARK 465       A 2   103                                                      
REMARK 465       C 2   104                                                      
REMARK 465       A 2   105                                                      
REMARK 465       A 2   106                                                      
REMARK 465       U 2   107                                                      
REMARK 465       A 2   108                                                      
REMARK 465       C 2   109                                                      
REMARK 465       A 2   110                                                      
REMARK 465       C 2   111                                                      
REMARK 465       A 2   112                                                      
REMARK 465       U 2   113                                                      
REMARK 465       U 2   114                                                      
REMARK 465       U 2   115                                                      
REMARK 465       U 2   116                                                      
REMARK 465       U 2   117                                                      
REMARK 465       U 2   118                                                      
REMARK 465       G 2   119                                                      
REMARK 465       G 2   120                                                      
REMARK 465       C 2   121                                                      
REMARK 465       A 2   122                                                      
REMARK 465       C 2   123                                                      
REMARK 465       C 2   124                                                      
REMARK 465       C 2   125                                                      
REMARK 465       A 2   126                                                      
REMARK 465       A 2   127                                                      
REMARK 465       A 2   128                                                      
REMARK 465       A 2   129                                                      
REMARK 465       U 2   130                                                      
REMARK 465       A 2   131                                                      
REMARK 465       A 2   132                                                      
REMARK 465       U 2   133                                                      
REMARK 465       A 2   134                                                      
REMARK 465       A 2   135                                                      
REMARK 465       A 2   136                                                      
REMARK 465       A 2   137                                                      
REMARK 465       U 2   138                                                      
REMARK 465       G 2   139                                                      
REMARK 465       G 2   140                                                      
REMARK 465       A 2   141                                                      
REMARK 465       C 2   142                                                      
REMARK 465       G 2   143                                                      
REMARK 465       G 2   144                                                      
REMARK 465       G 2   145                                                      
REMARK 465       A 2   146                                                      
REMARK 465       A 2   147                                                      
REMARK 465       G 2   148                                                      
REMARK 465       A 2   149                                                      
REMARK 465       G 2   150                                                      
REMARK 465       A 2   151                                                      
REMARK 465       C 2   152                                                      
REMARK 465       U 2   153                                                      
REMARK 465       U 2   154                                                      
REMARK 465       U 2   155                                                      
REMARK 465       U 2   156                                                      
REMARK 465       U 2   157                                                      
REMARK 465       A 2   158                                                      
REMARK 465       A 2   159                                                      
REMARK 465       G 2   160                                                      
REMARK 465       C 2   161                                                      
REMARK 465       A 2   162                                                      
REMARK 465       A 2   163                                                      
REMARK 465       G 2   164                                                      
REMARK 465       U 2   165                                                      
REMARK 465       U 2   166                                                      
REMARK 465       G 2   167                                                      
REMARK 465       U 2   168                                                      
REMARK 465       U 2   169                                                      
REMARK 465       U 2   170                                                      
REMARK 465       U 2   171                                                      
REMARK 465       C 2   172                                                      
REMARK 465       C 2   173                                                      
REMARK 465       G 2   174                                                      
REMARK 465       C 2   175                                                      
REMARK 465       U 2   176                                                      
REMARK 465       A 2   177                                                      
REMARK 465       A 2   178                                                      
REMARK 465       U 2   179                                                      
REMARK 465       G 2   180                                                      
REMARK 465       U 2   181                                                      
REMARK 465       C 2   182                                                      
REMARK 465       A 2   183                                                      
REMARK 465       G 2   184                                                      
REMARK 465       G 2   185                                                      
REMARK 465       U 2   186                                                      
REMARK 465       C 2   187                                                      
REMARK 465       U 2   188                                                      
REMARK 465       C 2   189                                                      
REMARK 465       A 2   190                                                      
REMARK 465       C 2   191                                                      
REMARK 465       U 2   192                                                      
REMARK 465       A 2   193                                                      
REMARK 465       C 2   194                                                      
REMARK 465       U 2   195                                                      
REMARK 465       U 2   196                                                      
REMARK 465       U 2   197                                                      
REMARK 465       U 2   198                                                      
REMARK 465       U 2   199                                                      
REMARK 465       G 2   200                                                      
REMARK 465       C 2   201                                                      
REMARK 465       U 2   202                                                      
REMARK 465       G 2   203                                                      
REMARK 465       C 2   204                                                      
REMARK 465       U 2   205                                                      
REMARK 465       A 2   206                                                      
REMARK 465       U 2   207                                                      
REMARK 465       U 2   208                                                      
REMARK 465       U 2   209                                                      
REMARK 465       U 2   210                                                      
REMARK 465       U 2   211                                                      
REMARK 465       C 2   212                                                      
REMARK 465       U 2   213                                                      
REMARK 465       U 2   214                                                      
REMARK 465       C 2   215                                                      
REMARK 465       G 2   216                                                      
REMARK 465       C 2   217                                                      
REMARK 465       U 2   218                                                      
REMARK 465       C 2   219                                                      
REMARK 465       A 2   220                                                      
REMARK 465       U 2   221                                                      
REMARK 465       G 2   222                                                      
REMARK 465       G 2   223                                                      
REMARK 465       U 2   224                                                      
REMARK 465       U 2   225                                                      
REMARK 465       U 2   226                                                      
REMARK 465       C 2   227                                                      
REMARK 465       U 2   228                                                      
REMARK 465       U 2   229                                                      
REMARK 465       C 2   230                                                      
REMARK 465       A 2   231                                                      
REMARK 465       U 2   232                                                      
REMARK 465       A 2   233                                                      
REMARK 465       A 2   234                                                      
REMARK 465       G 2   235                                                      
REMARK 465       G 2   236                                                      
REMARK 465       C 2   237                                                      
REMARK 465       G 2   238                                                      
REMARK 465       U 2   239                                                      
REMARK 465       U 2   240                                                      
REMARK 465       U 2   241                                                      
REMARK 465       U 2   242                                                      
REMARK 465       U 2   243                                                      
REMARK 465       A 2   244                                                      
REMARK 465       U 2   245                                                      
REMARK 465       G 2   246                                                      
REMARK 465       A 2   247                                                      
REMARK 465       U 2   248                                                      
REMARK 465       G 2   249                                                      
REMARK 465       G 2   250                                                      
REMARK 465       U 2   251                                                      
REMARK 465       U 2   252                                                      
REMARK 465       U 2   253                                                      
REMARK 465       U 2   254                                                      
REMARK 465       U 2   255                                                      
REMARK 465       C 2   256                                                      
REMARK 465       G 2   257                                                      
REMARK 465       A 2   258                                                      
REMARK 465       A 2   259                                                      
REMARK 465       A 2   260                                                      
REMARK 465       U 2   261                                                      
REMARK 465       U 2   262                                                      
REMARK 465       G 2   263                                                      
REMARK 465       G 2   264                                                      
REMARK 465       U 2   265                                                      
REMARK 465       U 2   266                                                      
REMARK 465       U 2   267                                                      
REMARK 465       U 2   268                                                      
REMARK 465       U 2   269                                                      
REMARK 465       G 2   270                                                      
REMARK 465       A 2   271                                                      
REMARK 465       G 2   272                                                      
REMARK 465       A 2   273                                                      
REMARK 465       C 2   274                                                      
REMARK 465       G 2   275                                                      
REMARK 465       A 2   276                                                      
REMARK 465       C 2   277                                                      
REMARK 465       G 2   278                                                      
REMARK 465       G 2   279                                                      
REMARK 465       U 2   280                                                      
REMARK 465       U 2   281                                                      
REMARK 465       G 2   282                                                      
REMARK 465       C 2   283                                                      
REMARK 465       U 2   284                                                      
REMARK 465       C 2   285                                                      
REMARK 465       A 2   286                                                      
REMARK 465       A 2   287                                                      
REMARK 465       G 2   288                                                      
REMARK 465       G 2   289                                                      
REMARK 465       U 2   290                                                      
REMARK 465       U 2   291                                                      
REMARK 465       A 2   292                                                      
REMARK 465       U 2   293                                                      
REMARK 465       U 2   294                                                      
REMARK 465       G 2   295                                                      
REMARK 465       U 2   296                                                      
REMARK 465       U 2   297                                                      
REMARK 465       U 2   298                                                      
REMARK 465       U 2   299                                                      
REMARK 465       U 2   300                                                      
REMARK 465       G 2   301                                                      
REMARK 465       U 2   302                                                      
REMARK 465       U 2   303                                                      
REMARK 465       U 2   304                                                      
REMARK 465       U 2   305                                                      
REMARK 465       C 2   306                                                      
REMARK 465       U 2   307                                                      
REMARK 465       U 2   308                                                      
REMARK 465       C 2   309                                                      
REMARK 465       U 2   310                                                      
REMARK 465       G 2   311                                                      
REMARK 465       G 2   312                                                      
REMARK 465       U 2   313                                                      
REMARK 465       U 2   314                                                      
REMARK 465       G 2   315                                                      
REMARK 465       U 2   316                                                      
REMARK 465       U 2   317                                                      
REMARK 465       U 2   318                                                      
REMARK 465       U 2   319                                                      
REMARK 465       C 2   320                                                      
REMARK 465       U 2   321                                                      
REMARK 465       A 2   322                                                      
REMARK 465       U 2   323                                                      
REMARK 465       U 2   324                                                      
REMARK 465       U 2   325                                                      
REMARK 465       U 2   326                                                      
REMARK 465       C 2   327                                                      
REMARK 465       U 2   328                                                      
REMARK 465       U 2   329                                                      
REMARK 465       U 2   330                                                      
REMARK 465       U 2   331                                                      
REMARK 465       U 2   332                                                      
REMARK 465       U 2   333                                                      
REMARK 465       U 2   334                                                      
REMARK 465       U 2   335                                                      
REMARK 465       A 2   336                                                      
REMARK 465       G 2   337                                                      
REMARK 465       C 2   338                                                      
REMARK 465       U 2   339                                                      
REMARK 465       U 2   340                                                      
REMARK 465       U 2   341                                                      
REMARK 465       C 2   342                                                      
REMARK 465       U 2   343                                                      
REMARK 465       G 2   344                                                      
REMARK 465       U 2   345                                                      
REMARK 465       U 2   346                                                      
REMARK 465       U 2   347                                                      
REMARK 465       C 2   348                                                      
REMARK 465       U 2   349                                                      
REMARK 465       C 2   350                                                      
REMARK 465       C 2   351                                                      
REMARK 465       C 2   352                                                      
REMARK 465       U 2   353                                                      
REMARK 465       U 2   354                                                      
REMARK 465       A 2   355                                                      
REMARK 465       G 2   356                                                      
REMARK 465       U 2   357                                                      
REMARK 465       U 2   358                                                      
REMARK 465       U 2   359                                                      
REMARK 465       G 2   360                                                      
REMARK 465       G 2   361                                                      
REMARK 465       C 2   362                                                      
REMARK 465       U 2   363                                                      
REMARK 465       U 2   364                                                      
REMARK 465       U 2   365                                                      
REMARK 465       U 2   366                                                      
REMARK 465       U 2   367                                                      
REMARK 465       G 2   368                                                      
REMARK 465       C 2   369                                                      
REMARK 465       U 2   370                                                      
REMARK 465       U 2   371                                                      
REMARK 465       C 2   372                                                      
REMARK 465       A 2   373                                                      
REMARK 465       U 2   374                                                      
REMARK 465       A 2   375                                                      
REMARK 465       C 2   376                                                      
REMARK 465       U 2   377                                                      
REMARK 465       C 2   378                                                      
REMARK 465       U 2   379                                                      
REMARK 465       U 2   380                                                      
REMARK 465       C 2   381                                                      
REMARK 465       C 2   382                                                      
REMARK 465       C 2   383                                                      
REMARK 465       U 2   384                                                      
REMARK 465       G 2   385                                                      
REMARK 465       U 2   386                                                      
REMARK 465       C 2   387                                                      
REMARK 465       U 2   388                                                      
REMARK 465       U 2   389                                                      
REMARK 465       U 2   390                                                      
REMARK 465       C 2   391                                                      
REMARK 465       C 2   392                                                      
REMARK 465       G 2   393                                                      
REMARK 465       A 2   394                                                      
REMARK 465       G 2   395                                                      
REMARK 465       C 2   396                                                      
REMARK 465       C 2   397                                                      
REMARK 465       G 2   398                                                      
REMARK 465       U 2   399                                                      
REMARK 465       U 2   400                                                      
REMARK 465       U 2   401                                                      
REMARK 465       A 2   402                                                      
REMARK 465       U 2   403                                                      
REMARK 465       G 2   404                                                      
REMARK 465       U 2   405                                                      
REMARK 465       C 2   406                                                      
REMARK 465       C 2   407                                                      
REMARK 465       A 2   408                                                      
REMARK 465       A 2   409                                                      
REMARK 465       C 2   410                                                      
REMARK 465       G 2   411                                                      
REMARK 465       C 2   412                                                      
REMARK 465       G 2   413                                                      
REMARK 465       G 2   414                                                      
REMARK 465       G 2   415                                                      
REMARK 465       A 2   416                                                      
REMARK 465       U 2   417                                                      
REMARK 465       U 2   418                                                      
REMARK 465       U 2   419                                                      
REMARK 465       G 2   420                                                      
REMARK 465       G 2   421                                                      
REMARK 465       U 2   422                                                      
REMARK 465       U 2   423                                                      
REMARK 465       U 2   424                                                      
REMARK 465       U 2   425                                                      
REMARK 465       U 2   426                                                      
REMARK 465       C 2   427                                                      
REMARK 465       U 2   428                                                      
REMARK 465       U 2   429                                                      
REMARK 465       U 2   430                                                      
REMARK 465       A 2   431                                                      
REMARK 465       U 2   432                                                      
REMARK 465       C 2   433                                                      
REMARK 465       G 2   434                                                      
REMARK 465       A 2   435                                                      
REMARK 465       U 2   436                                                      
REMARK 465       G 2   437                                                      
REMARK 465       G 2   438                                                      
REMARK 465       G 2   439                                                      
REMARK 465       A 2   440                                                      
REMARK 465       A 2   441                                                      
REMARK 465       G 2   442                                                      
REMARK 465       A 2   443                                                      
REMARK 465       A 2   444                                                      
REMARK 465       A 2   445                                                      
REMARK 465       U 2   446                                                      
REMARK 465       G 2   447                                                      
REMARK 465       G 2   448                                                      
REMARK 465       U 2   449                                                      
REMARK 465       G 2   450                                                      
REMARK 465       C 2   451                                                      
REMARK 465       U 2   452                                                      
REMARK 465       A 2   453                                                      
REMARK 465       U 2   454                                                      
REMARK 465       A 2   455                                                      
REMARK 465       G 2   456                                                      
REMARK 465       U 2   457                                                      
REMARK 465       A 2   458                                                      
REMARK 465       G 2   459                                                      
REMARK 465       G 2   460                                                      
REMARK 465       U 2   461                                                      
REMARK 465       U 2   462                                                      
REMARK 465       G 2   463                                                      
REMARK 465       G 2   464                                                      
REMARK 465       G 2   465                                                      
REMARK 465       A 2   466                                                      
REMARK 465       G 2   467                                                      
REMARK 465       A 2   468                                                      
REMARK 465       U 2   469                                                      
REMARK 465       A 2   470                                                      
REMARK 465       A 2   471                                                      
REMARK 465       U 2   472                                                      
REMARK 465       A 2   473                                                      
REMARK 465       U 2   474                                                      
REMARK 465       U 2   475                                                      
REMARK 465       U 2   476                                                      
REMARK 465       A 2   477                                                      
REMARK 465       U 2   478                                                      
REMARK 465       G 2   479                                                      
REMARK 465       G 2   480                                                      
REMARK 465       U 2   481                                                      
REMARK 465       A 2   482                                                      
REMARK 465       U 2   483                                                      
REMARK 465       G 2   484                                                      
REMARK 465       G 2   485                                                      
REMARK 465       G 2   486                                                      
REMARK 465       G 2   487                                                      
REMARK 465       U 2   488                                                      
REMARK 465       G 2   489                                                      
REMARK 465       C 2   490                                                      
REMARK 465       U 2   491                                                      
REMARK 465       A 2   492                                                      
REMARK 465       G 2   493                                                      
REMARK 465       U 2   494                                                      
REMARK 465       G 2   495                                                      
REMARK 465       C 2   496                                                      
REMARK 465       G 2   497                                                      
REMARK 465       G 2   498                                                      
REMARK 465       A 2   499                                                      
REMARK 465       U 2   500                                                      
REMARK 465       G 2   501                                                      
REMARK 465       G 2   502                                                      
REMARK 465       G 2   503                                                      
REMARK 465       G 2   504                                                      
REMARK 465       C 2   505                                                      
REMARK 465       G 2   506                                                      
REMARK 465       C 2   507                                                      
REMARK 465       U 2   508                                                      
REMARK 465       C 2   509                                                      
REMARK 465       U 2   510                                                      
REMARK 465       U 2   511                                                      
REMARK 465       A 2   512                                                      
REMARK 465       U 2   513                                                      
REMARK 465       U 2   514                                                      
REMARK 465       G 2   515                                                      
REMARK 465       U 2   516                                                      
REMARK 465       U 2   517                                                      
REMARK 465       G 2   518                                                      
REMARK 465       A 2   519                                                      
REMARK 465       U 2   520                                                      
REMARK 465       U 2   521                                                      
REMARK 465       U 2   522                                                      
REMARK 465       C 2   523                                                      
REMARK 465       U 2   524                                                      
REMARK 465       U 2   525                                                      
REMARK 465       C 2   526                                                      
REMARK 465       G 2   527                                                      
REMARK 465       C 2   528                                                      
REMARK 465       U 2   529                                                      
REMARK 465       C 2   530                                                      
REMARK 465       G 2   531                                                      
REMARK 465       U 2   532                                                      
REMARK 465       C 2   533                                                      
REMARK 465       U 2   534                                                      
REMARK 465       U 2   535                                                      
REMARK 465       C 2   536                                                      
REMARK 465       U 2   537                                                      
REMARK 465       U 2   538                                                      
REMARK 465       U 2   539                                                      
REMARK 465       U 2   540                                                      
REMARK 465       U 2   541                                                      
REMARK 465       C 2   542                                                      
REMARK 465       U 2   543                                                      
REMARK 465       G 2   544                                                      
REMARK 465       G 2   545                                                      
REMARK 465       U 2   546                                                      
REMARK 465       G 2   547                                                      
REMARK 465       G 2   548                                                      
REMARK 465       C 2   549                                                      
REMARK 465       G 2   550                                                      
REMARK 465       C 2   551                                                      
REMARK 465       U 2   552                                                      
REMARK 465       G 2   553                                                      
REMARK 465       C 2   554                                                      
REMARK 465       A 2   555                                                      
REMARK 465       A 2   556                                                      
REMARK 465       G 2   557                                                      
REMARK 465       A 2   558                                                      
REMARK 465       G 2   559                                                      
REMARK 465       G 2   560                                                      
REMARK 465       A 2   561                                                      
REMARK 465       A 2   562                                                      
REMARK 465       G 2   563                                                      
REMARK 465       U 2   564                                                      
REMARK 465       U 2   565                                                      
REMARK 465       U 2   566                                                      
REMARK 465       U 2   567                                                      
REMARK 465       U 2   568                                                      
REMARK 465       C 2   569                                                      
REMARK 465       G 2   570                                                      
REMARK 465       A 2   571                                                      
REMARK 465       C 2   572                                                      
REMARK 465       U 2   573                                                      
REMARK 465       U 2   574                                                      
REMARK 465       U 2   575                                                      
REMARK 465       G 2   576                                                      
REMARK 465       U 2   577                                                      
REMARK 465       U 2   578                                                      
REMARK 465       A 2   579                                                      
REMARK 465       U 2   580                                                      
REMARK 465       G 2   581                                                      
REMARK 465       A 2   582                                                      
REMARK 465       U 2   583                                                      
REMARK 465       U 2   584                                                      
REMARK 465       U 2   585                                                      
REMARK 465       U 2   586                                                      
REMARK 465       U 2   587                                                      
REMARK 465       G 2   588                                                      
REMARK 465       G 2   589                                                      
REMARK 465       U 2   590                                                      
REMARK 465       U 2   591                                                      
REMARK 465       U 2   592                                                      
REMARK 465       G 2   593                                                      
REMARK 465       C 2   594                                                      
REMARK 465       A 2   595                                                      
REMARK 465       A 2   596                                                      
REMARK 465       G 2   597                                                      
REMARK 465       G 2   598                                                      
REMARK 465       A 2   599                                                      
REMARK 465       A 2   600                                                      
REMARK 465       A 2   601                                                      
REMARK 465       G 2   602                                                      
REMARK 465       G 2   603                                                      
REMARK 465       U 2   604                                                      
REMARK 465       G 2   605                                                      
REMARK 465       U 2   606                                                      
REMARK 465       C 2   607                                                      
REMARK 465       U 2   608                                                      
REMARK 465       U 2   609                                                      
REMARK 465       A 2   610                                                      
REMARK 465       C 2   611                                                      
REMARK 465       G 2   612                                                      
REMARK 465       A 2   613                                                      
REMARK 465       U 2   614                                                      
REMARK 465       U 2   615                                                      
REMARK 465       C 2   616                                                      
REMARK 465       U 2   617                                                      
REMARK 465       U 2   618                                                      
REMARK 465       U 2   619                                                      
REMARK 465       U 2   620                                                      
REMARK 465       U 2   621                                                      
REMARK 465       U 2   622                                                      
REMARK 465       U 2   623                                                      
REMARK 465       G 2   624                                                      
REMARK 465       A 2   625                                                      
REMARK 465       U 2   626                                                      
REMARK 465       G 2   627                                                      
REMARK 465       U 2   628                                                      
REMARK 465       A 2   629                                                      
REMARK 465       A 2   630                                                      
REMARK 465       U 2   631                                                      
REMARK 465       A 2   632                                                      
REMARK 465       G 2   633                                                      
REMARK 465       G 2   634                                                      
REMARK 465       A 2   635                                                      
REMARK 465       U 2   636                                                      
REMARK 465       A 2   637                                                      
REMARK 465       A 2   638                                                      
REMARK 465       G 2   639                                                      
REMARK 465       C 2   640                                                      
REMARK 465       U 2   641                                                      
REMARK 465       U 2   642                                                      
REMARK 465       G 2   643                                                      
REMARK 465       C 2   644                                                      
REMARK 465       U 2   645                                                      
REMARK 465       U 2   646                                                      
REMARK 465       A 2   647                                                      
REMARK 465       U 2   648                                                      
REMARK 465       C 2   649                                                      
REMARK 465       C 2   650                                                      
REMARK 465       C 2   651                                                      
REMARK 465       C 2   652                                                      
REMARK 465       C 2   653                                                      
REMARK 465       A 2   654                                                      
REMARK 465       A 2   655                                                      
REMARK 465       G 2   656                                                      
REMARK 465       U 2   657                                                      
REMARK 465       A 2   658                                                      
REMARK 465       U 2   659                                                      
REMARK 465       C 2   660                                                      
REMARK 465       G 2   661                                                      
REMARK 465       G 2   662                                                      
REMARK 465       C 2   663                                                      
REMARK 465       C 2   664                                                      
REMARK 465       A 2   665                                                      
REMARK 465       A 2   666                                                      
REMARK 465       A 2   667                                                      
REMARK 465       G 2   668                                                      
REMARK 465       U 2   669                                                      
REMARK 465       U 2   670                                                      
REMARK 465       G 2   671                                                      
REMARK 465       U 2   672                                                      
REMARK 465       U 2   673                                                      
REMARK 465       G 2   674                                                      
REMARK 465       A 2   675                                                      
REMARK 465       U 2   676                                                      
REMARK 465       U 2   677                                                      
REMARK 465       U 2   678                                                      
REMARK 465       U 2   679                                                      
REMARK 465       C 2   680                                                      
REMARK 465       C 2   681                                                      
REMARK 465       U 2   682                                                      
REMARK 465       U 2   683                                                      
REMARK 465       U 2   684                                                      
REMARK 465       U 2   685                                                      
REMARK 465       G 2   686                                                      
REMARK 465       A 2   687                                                      
REMARK 465       A 2   688                                                      
REMARK 465       G 2   689                                                      
REMARK 465       U 2   690                                                      
REMARK 465       G 2   691                                                      
REMARK 465       U 2   692                                                      
REMARK 465       C 2   693                                                      
REMARK 465       C 2   694                                                      
REMARK 465       U 2   695                                                      
REMARK 465       C 2   696                                                      
REMARK 465       G 2   697                                                      
REMARK 465       G 2   698                                                      
REMARK 465       U 2   699                                                      
REMARK 465       U 2   700                                                      
REMARK 465       U 2   701                                                      
REMARK 465       G 2   702                                                      
REMARK 465       A 2   703                                                      
REMARK 465       G 2   704                                                      
REMARK 465       G 2   705                                                      
REMARK 465       G 2   706                                                      
REMARK 465       G 2   707                                                      
REMARK 465       G 2   708                                                      
REMARK 465       U 2   709                                                      
REMARK 465       G 2   710                                                      
REMARK 465       U 2   711                                                      
REMARK 465       A 2   712                                                      
REMARK 465       G 2   713                                                      
REMARK 465       G 2   714                                                      
REMARK 465       G 2   715                                                      
REMARK 465       U 2   716                                                      
REMARK 465       G 2   717                                                      
REMARK 465       G 2   718                                                      
REMARK 465       G 2   719                                                      
REMARK 465       G 2   720                                                      
REMARK 465       U 2   721                                                      
REMARK 465       U 2   722                                                      
REMARK 465       G 2   723                                                      
REMARK 465       G 2   724                                                      
REMARK 465       U 2   725                                                      
REMARK 465       C 2   726                                                      
REMARK 465       U 2   727                                                      
REMARK 465       A 2   728                                                      
REMARK 465       C 2   729                                                      
REMARK 465       A 2   730                                                      
REMARK 465       A 2   731                                                      
REMARK 465       U 2   732                                                      
REMARK 465       A 2   733                                                      
REMARK 465       A 2   734                                                      
REMARK 465       G 2   735                                                      
REMARK 465       A 2   736                                                      
REMARK 465       G 2   737                                                      
REMARK 465       U 2   738                                                      
REMARK 465       G 2   739                                                      
REMARK 465       U 2   740                                                      
REMARK 465       U 2   741                                                      
REMARK 465       C 2   742                                                      
REMARK 465       C 2   743                                                      
REMARK 465       A 2   744                                                      
REMARK 465       U 2   745                                                      
REMARK 465       U 2   746                                                      
REMARK 465       G 2   747                                                      
REMARK 465       U 2   748                                                      
REMARK 465       U 2   749                                                      
REMARK 465       A 2   750                                                      
REMARK 465       A 2   751                                                      
REMARK 465       C 2   752                                                      
REMARK 465       G 2   753                                                      
REMARK 465       U 2   754                                                      
REMARK 465       G 2   755                                                      
REMARK 465       C 2   756                                                      
REMARK 465       U 2   757                                                      
REMARK 465       G 2   758                                                      
REMARK 465       G 2   759                                                      
REMARK 465       C 2   760                                                      
REMARK 465       G 2   761                                                      
REMARK 465       U 2   762                                                      
REMARK 465       C 2   763                                                      
REMARK 465       U 2   764                                                      
REMARK 465       U 2   765                                                      
REMARK 465       U 2   766                                                      
REMARK 465       U 2   767                                                      
REMARK 465       A 2   768                                                      
REMARK 465       C 2   769                                                      
REMARK 465       U 2   770                                                      
REMARK 465       A 2   771                                                      
REMARK 465       U 2   772                                                      
REMARK 465       A 2   773                                                      
REMARK 465       U 2   774                                                      
REMARK 465       U 2   775                                                      
REMARK 465       U 2   776                                                      
REMARK 465       U 2   777                                                      
REMARK 465       U 2   778                                                      
REMARK 465       U 2   779                                                      
REMARK 465       U 2   780                                                      
REMARK 465       U 2   781                                                      
REMARK 465       C 2   782                                                      
REMARK 465       C 2   783                                                      
REMARK 465       C 2   784                                                      
REMARK 465       A 2   785                                                      
REMARK 465       G 2   786                                                      
REMARK 465       U 2   787                                                      
REMARK 465       U 2   788                                                      
REMARK 465       U 2   789                                                      
REMARK 465       A 2   790                                                      
REMARK 465       U 2   791                                                      
REMARK 465       U 2   792                                                      
REMARK 465       U 2   793                                                      
REMARK 465       U 2   794                                                      
REMARK 465       G 2   795                                                      
REMARK 465       U 2   796                                                      
REMARK 465       G 2   797                                                      
REMARK 465       C 2   798                                                      
REMARK 465       U 2   799                                                      
REMARK 465       U 2   800                                                      
REMARK 465       A 2   801                                                      
REMARK 465       U 2   802                                                      
REMARK 465       U 2   803                                                      
REMARK 465       U 2   804                                                      
REMARK 465       U 2   805                                                      
REMARK 465       C 2   806                                                      
REMARK 465       U 2   807                                                      
REMARK 465       C 2   808                                                      
REMARK 465       A 2   809                                                      
REMARK 465       U 2   810                                                      
REMARK 465       U 2   811                                                      
REMARK 465       G 2   812                                                      
REMARK 465       A 2   813                                                      
REMARK 465       G 2   814                                                      
REMARK 465       G 2   815                                                      
REMARK 465       A 2   816                                                      
REMARK 465       G 2   817                                                      
REMARK 465       A 2   818                                                      
REMARK 465       A 2   819                                                      
REMARK 465       G 2   820                                                      
REMARK 465       G 2   821                                                      
REMARK 465       A 2   822                                                      
REMARK 465       G 2   823                                                      
REMARK 465       C 2   824                                                      
REMARK 465       U 2   825                                                      
REMARK 465       C 2   826                                                      
REMARK 465       U 2   827                                                      
REMARK 465       U 2   828                                                      
REMARK 465       C 2   829                                                      
REMARK 465       U 2   830                                                      
REMARK 465       C 2   831                                                      
REMARK 465       G 2   832                                                      
REMARK 465       C 2   833                                                      
REMARK 465       A 2   834                                                      
REMARK 465       G 2   835                                                      
REMARK 465       G 2   836                                                      
REMARK 465       A 2   837                                                      
REMARK 465       U 2   838                                                      
REMARK 465       A 2   839                                                      
REMARK 465       U 2   840                                                      
REMARK 465       A 2   841                                                      
REMARK 465       A 2   842                                                      
REMARK 465       A 2   843                                                      
REMARK 465       U 2   844                                                      
REMARK 465       G 2   845                                                      
REMARK 465       G 2   846                                                      
REMARK 465       A 2   847                                                      
REMARK 465       G 2   848                                                      
REMARK 465       G 2   849                                                      
REMARK 465       U 2   850                                                      
REMARK 465       U 2   851                                                      
REMARK 465       U 2   852                                                      
REMARK 465       G 2   853                                                      
REMARK 465       C 2   854                                                      
REMARK 465       U 2   855                                                      
REMARK 465       A 2   856                                                      
REMARK 465       A 2   857                                                      
REMARK 465       A 2   858                                                      
REMARK 465       G 2   859                                                      
REMARK 465       G 2   860                                                      
REMARK 465       G 2   861                                                      
REMARK 465       G 2   862                                                      
REMARK 465       A 2   863                                                      
REMARK 465       G 2   864                                                      
REMARK 465       G 2   865                                                      
REMARK 465       A 2   866                                                      
REMARK 465       G 2   867                                                      
REMARK 465       A 2   868                                                      
REMARK 465       U 2   869                                                      
REMARK 465       G 2   870                                                      
REMARK 465       U 2   871                                                      
REMARK 465       G 2   872                                                      
REMARK 465       U 2   873                                                      
REMARK 465       U 2   874                                                      
REMARK 465       U 2   875                                                      
REMARK 465       G 2   876                                                      
REMARK 465       U 2   877                                                      
REMARK 465       G 2   878                                                      
REMARK 465       A 2   879                                                      
REMARK 465       G 2   880                                                      
REMARK 465       A 2   881                                                      
REMARK 465       A 2   882                                                      
REMARK 465       U 2   883                                                      
REMARK 465       A 2   884                                                      
REMARK 465       C 2   885                                                      
REMARK 465       U 2   886                                                      
REMARK 465       G 2   887                                                      
REMARK 465       C 2   888                                                      
REMARK 465       U 2   889                                                      
REMARK 465       G 2   890                                                      
REMARK 465       A 2   891                                                      
REMARK 465       G 2   892                                                      
REMARK 465       A 2   893                                                      
REMARK 465       G 2   894                                                      
REMARK 465       A 2   895                                                      
REMARK 465       G 2   896                                                      
REMARK 465       U 2   897                                                      
REMARK 465       U 2   898                                                      
REMARK 465       C 2   899                                                      
REMARK 465       U 2   900                                                      
REMARK 465       G 2   901                                                      
REMARK 465       G 2   902                                                      
REMARK 465       A 2   903                                                      
REMARK 465       A 2   904                                                      
REMARK 465       G 2   905                                                      
REMARK 465       A 2   906                                                      
REMARK 465       G 2   907                                                      
REMARK 465       A 2   908                                                      
REMARK 465       A 2   909                                                      
REMARK 465       A 2   910                                                      
REMARK 465       A 2   911                                                      
REMARK 465       A 2   912                                                      
REMARK 465       A 2   913                                                      
REMARK 465       A 2   914                                                      
REMARK 465       G 2   915                                                      
REMARK 465       G 2   916                                                      
REMARK 465       A 2   917                                                      
REMARK 465       G 2   918                                                      
REMARK 465       G 2   919                                                      
REMARK 465       C 2   920                                                      
REMARK 465       A 2   921                                                      
REMARK 465       A 2   922                                                      
REMARK 465       U 2   923                                                      
REMARK 465       G 2   924                                                      
REMARK 465       G 2   925                                                      
REMARK 465       A 2   926                                                      
REMARK 465       A 2   927                                                      
REMARK 465       G 2   928                                                      
REMARK 465       G 2   929                                                      
REMARK 465       C 2   930                                                      
REMARK 465       G 2   931                                                      
REMARK 465       U 2   932                                                      
REMARK 465       U 2   933                                                      
REMARK 465       U 2   934                                                      
REMARK 465       G 2   935                                                      
REMARK 465       C 2   936                                                      
REMARK 465       U 2   937                                                      
REMARK 465       G 2   938                                                      
REMARK 465       G 2   939                                                      
REMARK 465       G 2   940                                                      
REMARK 465       A 2   941                                                      
REMARK 465       A 2   942                                                      
REMARK 465       A 2   943                                                      
REMARK 465       A 2   944                                                      
REMARK 465       G 2   945                                                      
REMARK 465       A 2   946                                                      
REMARK 465       G 2   947                                                      
REMARK 465       A 2   948                                                      
REMARK 465       A 2   949                                                      
REMARK 465       G 2   950                                                      
REMARK 465       A 2   951                                                      
REMARK 465       G 2   952                                                      
REMARK 465       C 2   953                                                      
REMARK 465       C 2   954                                                      
REMARK 465       A 2   955                                                      
REMARK 465       U 2   956                                                      
REMARK 465       G 2   957                                                      
REMARK 465       A 2   958                                                      
REMARK 465       C 2   959                                                      
REMARK 465       U 2   960                                                      
REMARK 465       G 2   961                                                      
REMARK 465       C 2   962                                                      
REMARK 465       A 2   963                                                      
REMARK 465       U 2   964                                                      
REMARK 465       C 2   965                                                      
REMARK 465       U 2   966                                                      
REMARK 465       G 2   967                                                      
REMARK 465       U 2   968                                                      
REMARK 465       U 2   969                                                      
REMARK 465       G 2   970                                                      
REMARK 465       U 2   971                                                      
REMARK 465       U 2   972                                                      
REMARK 465       U 2   973                                                      
REMARK 465       C 2   974                                                      
REMARK 465       A 2   975                                                      
REMARK 465       A 2   976                                                      
REMARK 465       G 2   977                                                      
REMARK 465       G 2   978                                                      
REMARK 465       C 2   979                                                      
REMARK 465       C 2   980                                                      
REMARK 465       A 2   981                                                      
REMARK 465       G 2   982                                                      
REMARK 465       U 2   983                                                      
REMARK 465       U 2   984                                                      
REMARK 465       U 2   985                                                      
REMARK 465       U 2   986                                                      
REMARK 465       A 2   987                                                      
REMARK 465       U 2   988                                                      
REMARK 465       U 2   989                                                      
REMARK 465       A 2   990                                                      
REMARK 465       A 2   991                                                      
REMARK 465       C 2   992                                                      
REMARK 465       C 2   993                                                      
REMARK 465       G 2   994                                                      
REMARK 465       C 2   995                                                      
REMARK 465       C 2   996                                                      
REMARK 465       U 2   997                                                      
REMARK 465       A 2   998                                                      
REMARK 465       U 2   999                                                      
REMARK 465       G 2  1000                                                      
REMARK 465       U 2  1001                                                      
REMARK 465       C 2  1002                                                      
REMARK 465       A 2  1003                                                      
REMARK 465       U 2  1004                                                      
REMARK 465       A 2  1005                                                      
REMARK 465       G 2  1006                                                      
REMARK 465       A 2  1007                                                      
REMARK 465       G 2  1008                                                      
REMARK 465       G 2  1009                                                      
REMARK 465       C 2  1010                                                      
REMARK 465       G 2  1011                                                      
REMARK 465       U 2  1012                                                      
REMARK 465       U 2  1013                                                      
REMARK 465       U 2  1014                                                      
REMARK 465       U 2  1015                                                      
REMARK 465       U 2  1016                                                      
REMARK 465       U 2  1017                                                      
REMARK 465       U 2  1018                                                      
REMARK 465       U 2  1019                                                      
REMARK 465       G 2  1020                                                      
REMARK 465       G 2  1021                                                      
REMARK 465       A 2  1022                                                      
REMARK 465       G 2  1023                                                      
REMARK 465       G 2  1024                                                      
REMARK 465       G 2  1025                                                      
REMARK 465       A 2  1026                                                      
REMARK 465       U 2  1027                                                      
REMARK 465       U 2  1028                                                      
REMARK 465       U 2  1029                                                      
REMARK 465       G 2  1030                                                      
REMARK 465       A 2  1031                                                      
REMARK 465       A 2  1032                                                      
REMARK 465       G 2  1033                                                      
REMARK 465       A 2  1034                                                      
REMARK 465       A 2  1035                                                      
REMARK 465       U 2  1036                                                      
REMARK 465       G 2  1037                                                      
REMARK 465       C 2  1038                                                      
REMARK 465       C 2  1039                                                      
REMARK 465       G 2  1040                                                      
REMARK 465       G 2  1041                                                      
REMARK 465       C 2  1042                                                      
REMARK 465       G 2  1043                                                      
REMARK 465       G 2  1044                                                      
REMARK 465       C 2  1045                                                      
REMARK 465       A 2  1046                                                      
REMARK 465       U 2  1047                                                      
REMARK 465       C 2  1048                                                      
REMARK 465       A 2  1049                                                      
REMARK 465       A 2  1050                                                      
REMARK 465       G 2  1051                                                      
REMARK 465       A 2  1052                                                      
REMARK 465       A 2  1053                                                      
REMARK 465       A 2  1054                                                      
REMARK 465       C 2  1055                                                      
REMARK 465       G 2  1056                                                      
REMARK 465       G 2  1057                                                      
REMARK 465       A 2  1058                                                      
REMARK 465       C 2  1059                                                      
REMARK 465       U 2  1060                                                      
REMARK 465       U 2  1061                                                      
REMARK 465       G 2  1062                                                      
REMARK 465       A 2  1063                                                      
REMARK 465       U 2  1064                                                      
REMARK 465       G 2  1065                                                      
REMARK 465       G 2  1066                                                      
REMARK 465       U 2  1067                                                      
REMARK 465       U 2  1068                                                      
REMARK 465       G 2  1069                                                      
REMARK 465       A 2  1070                                                      
REMARK 465       C 2  1071                                                      
REMARK 465       G 2  1072                                                      
REMARK 465       C 2  1073                                                      
REMARK 465       C 2  1074                                                      
REMARK 465       U 2  1075                                                      
REMARK 465       G 2  1076                                                      
REMARK 465       U 2  1077                                                      
REMARK 465       U 2  1078                                                      
REMARK 465       U 2  1079                                                      
REMARK 465       U 2  1080                                                      
REMARK 465       U 2  1081                                                      
REMARK 465       A 2  1082                                                      
REMARK 465       A 2  1083                                                      
REMARK 465       A 2  1084                                                      
REMARK 465       G 2  1085                                                      
REMARK 465       U 2  1086                                                      
REMARK 465       U 2  1087                                                      
REMARK 465       A 2  1088                                                      
REMARK 465       G 2  1089                                                      
REMARK 465       A 2  1090                                                      
REMARK 465       G 2  1091                                                      
REMARK 465       A 2  1092                                                      
REMARK 465       C 2  1093                                                      
REMARK 465       G 2  1094                                                      
REMARK 465       U 2  1095                                                      
REMARK 465       C 2  1096                                                      
REMARK 465       G 2  1097                                                      
REMARK 465       C 2  1098                                                      
REMARK 465       G 2  1099                                                      
REMARK 465       A 2  1100                                                      
REMARK 465       C 2  1101                                                      
REMARK 465       C 2  1102                                                      
REMARK 465       C 2  1103                                                      
REMARK 465       U 2  1104                                                      
REMARK 465       C 2  1105                                                      
REMARK 465       G 2  1106                                                      
REMARK 465       C 2  1107                                                      
REMARK 465       A 2  1108                                                      
REMARK 465       C 2  1109                                                      
REMARK 465       U 2  1110                                                      
REMARK 465       U 2  1111                                                      
REMARK 465       G 2  1112                                                      
REMARK 465       U 2  1113                                                      
REMARK 465       G 2  1114                                                      
REMARK 465       G 2  1115                                                      
REMARK 465       A 2  1116                                                      
REMARK 465       G 2  1117                                                      
REMARK 465       U 2  1118                                                      
REMARK 465       C 2  1119                                                      
REMARK 465       G 2  1120                                                      
REMARK 465       U 2  1121                                                      
REMARK 465       U 2  1122                                                      
REMARK 465       C 2  1123                                                      
REMARK 465       U 2  1124                                                      
REMARK 465       U 2  1125                                                      
REMARK 465       G 2  1126                                                      
REMARK 465       A 2  1127                                                      
REMARK 465       C 2  1128                                                      
REMARK 465       U 2  1129                                                      
REMARK 465       U 2  1130                                                      
REMARK 465       U 2  1131                                                      
REMARK 465       U 2  1132                                                      
REMARK 465       A 2  1133                                                      
REMARK 465       C 2  1134                                                      
REMARK 465       U 2  1135                                                      
REMARK 465       U 2  1136                                                      
REMARK 465       U 2  1137                                                      
REMARK 465       G 2  1138                                                      
REMARK 465       G 2  1139                                                      
REMARK 465       U 2  1140                                                      
REMARK 465       C 2  1141                                                      
REMARK 465       G 2  1142                                                      
REMARK 465       C 2  1143                                                      
REMARK 465       U 2  1144                                                      
REMARK 465       U 2  1145                                                      
REMARK 465       G 2  1146                                                      
REMARK 465       A 2  1147                                                      
REMARK 465       U 2  1148                                                      
REMARK 465       G 2  1149                                                      
REMARK 465       U 2  1150                                                      
REMARK 465       U 2  1151                                                      
REMARK 465       U 2  1152                                                      
REMARK 465       C 2  1153                                                      
REMARK 465       U 2  1154                                                      
REMARK 465       C 2  1155                                                      
REMARK 465       U 2  1156                                                      
REMARK 465       C 2  1157                                                      
REMARK 465       G 2  1158                                                      
REMARK 465       U 2  1159                                                      
REMARK 465       C 2  1160                                                      
REMARK 465       U 2  1161                                                      
REMARK 465       U 2  1162                                                      
REMARK 465       C 2  1163                                                      
REMARK 465       C 2  1164                                                      
REMARK 465       C 2  1165                                                      
REMARK 465       G 2  1166                                                      
REMARK 465       U 2  1167                                                      
REMARK 465       U 2  1168                                                      
REMARK 465       C 2  1169                                                      
REMARK 465       G 2  1170                                                      
REMARK 465       C 2  1171                                                      
REMARK 465       U 2  1172                                                      
REMARK 465       C 2  1173                                                      
REMARK 465       U 2  1174                                                      
REMARK 465       U 2  1175                                                      
REMARK 465       U 6    11                                                      
REMARK 465       A 6    12                                                      
REMARK 465       A 6    13                                                      
REMARK 465       C 6    14                                                      
REMARK 465       C 6    15                                                      
REMARK 465       U 6   105                                                      
REMARK 465       U 6   106                                                      
REMARK 465       C 6   107                                                      
REMARK 465       G 6   108                                                      
REMARK 465       U 6   109                                                      
REMARK 465       U 6   110                                                      
REMARK 465       U 6   111                                                      
REMARK 465       U 6   112                                                      
REMARK 465       A 5     1                                                      
REMARK 465       A 5     2                                                      
REMARK 465       G 5     3                                                      
REMARK 465       C 5    54                                                      
REMARK 465       U 5    55                                                      
REMARK 465       U 5    56                                                      
REMARK 465       U 5    57                                                      
REMARK 465       U 5    58                                                      
REMARK 465       A 5    59                                                      
REMARK 465       U 5    60                                                      
REMARK 465       U 5    61                                                      
REMARK 465       C 5   146                                                      
REMARK 465       C 5   147                                                      
REMARK 465       G 5   148                                                      
REMARK 465       U 5   149                                                      
REMARK 465       U 5   150                                                      
REMARK 465       A 5   151                                                      
REMARK 465       C 5   152                                                      
REMARK 465       U 5   153                                                      
REMARK 465       G 5   154                                                      
REMARK 465       U 5   155                                                      
REMARK 465       G 5   156                                                      
REMARK 465       G 5   157                                                      
REMARK 465       G 5   158                                                      
REMARK 465       C 5   159                                                      
REMARK 465       U 5   160                                                      
REMARK 465       U 5   161                                                      
REMARK 465       G 5   162                                                      
REMARK 465       C 5   163                                                      
REMARK 465       C 5   164                                                      
REMARK 465       A 5   165                                                      
REMARK 465       U 5   166                                                      
REMARK 465       G 5   174                                                      
REMARK 465       G 5   175                                                      
REMARK 465       A 5   176                                                      
REMARK 465       A 5   177                                                      
REMARK 465       C 5   178                                                      
REMARK 465       U 5   179                                                      
REMARK 465     MET A     1                                                      
REMARK 465     SER A     2                                                      
REMARK 465     GLY A     3                                                      
REMARK 465     LEU A     4                                                      
REMARK 465     PRO A     5                                                      
REMARK 465     PRO A     6                                                      
REMARK 465     PRO A     7                                                      
REMARK 465     PRO A     8                                                      
REMARK 465     PRO A     9                                                      
REMARK 465     GLY A    10                                                      
REMARK 465     PHE A    11                                                      
REMARK 465     GLU A    12                                                      
REMARK 465     GLU A    13                                                      
REMARK 465     ASP A    14                                                      
REMARK 465     SER A    15                                                      
REMARK 465     ASP A    16                                                      
REMARK 465     LEU A    17                                                      
REMARK 465     ALA A    18                                                      
REMARK 465     LEU A    19                                                      
REMARK 465     PRO A    20                                                      
REMARK 465     PRO A    21                                                      
REMARK 465     PRO A    22                                                      
REMARK 465     PRO A    23                                                      
REMARK 465     PRO A    24                                                      
REMARK 465     PRO A    25                                                      
REMARK 465     PRO A    26                                                      
REMARK 465     PRO A    27                                                      
REMARK 465     GLY A    28                                                      
REMARK 465     TYR A    29                                                      
REMARK 465     GLU A    30                                                      
REMARK 465     ILE A    31                                                      
REMARK 465     GLU A    32                                                      
REMARK 465     GLU A    33                                                      
REMARK 465     LEU A    34                                                      
REMARK 465     ASP A    35                                                      
REMARK 465     ASN A    36                                                      
REMARK 465     PRO A    37                                                      
REMARK 465     MET A    38                                                      
REMARK 465     VAL A    39                                                      
REMARK 465     PRO A    40                                                      
REMARK 465     SER A    41                                                      
REMARK 465     SER A    42                                                      
REMARK 465     VAL A    43                                                      
REMARK 465     ASN A    44                                                      
REMARK 465     GLU A    45                                                      
REMARK 465     ASP A    46                                                      
REMARK 465     THR A    47                                                      
REMARK 465     PHE A    48                                                      
REMARK 465     LEU A    49                                                      
REMARK 465     PRO A    50                                                      
REMARK 465     PRO A    51                                                      
REMARK 465     PRO A    52                                                      
REMARK 465     PRO A    53                                                      
REMARK 465     PRO A    54                                                      
REMARK 465     PRO A    55                                                      
REMARK 465     PRO A    56                                                      
REMARK 465     SER A    57                                                      
REMARK 465     ASN A    58                                                      
REMARK 465     PHE A    59                                                      
REMARK 465     GLU A    60                                                      
REMARK 465     ILE A    61                                                      
REMARK 465     ASN A    62                                                      
REMARK 465     ALA A    63                                                      
REMARK 465     GLU A    64                                                      
REMARK 465     GLU A    65                                                      
REMARK 465     ILE A    66                                                      
REMARK 465     VAL A    67                                                      
REMARK 465     ASP A    68                                                      
REMARK 465     PHE A    69                                                      
REMARK 465     THR A    70                                                      
REMARK 465     LEU A    71                                                      
REMARK 465     PRO A    72                                                      
REMARK 465     PRO A    73                                                      
REMARK 465     PRO A    74                                                      
REMARK 465     PRO A    75                                                      
REMARK 465     PRO A    76                                                      
REMARK 465     PRO A    77                                                      
REMARK 465     PRO A    78                                                      
REMARK 465     GLY A    79                                                      
REMARK 465     LEU A    80                                                      
REMARK 465     ASP A    81                                                      
REMARK 465     GLU A    82                                                      
REMARK 465     LEU A    83                                                      
REMARK 465     GLU A    84                                                      
REMARK 465     THR A    85                                                      
REMARK 465     LYS A    86                                                      
REMARK 465     ALA A    87                                                      
REMARK 465     GLU A    88                                                      
REMARK 465     LYS A    89                                                      
REMARK 465     LYS A    90                                                      
REMARK 465     VAL A    91                                                      
REMARK 465     GLU A    92                                                      
REMARK 465     LEU A    93                                                      
REMARK 465     HIS A    94                                                      
REMARK 465     GLY A    95                                                      
REMARK 465     LYS A    96                                                      
REMARK 465     ARG A    97                                                      
REMARK 465     LYS A    98                                                      
REMARK 465     LEU A    99                                                      
REMARK 465     ASP A   100                                                      
REMARK 465     ILE A   101                                                      
REMARK 465     GLY A   102                                                      
REMARK 465     LYS A   103                                                      
REMARK 465     ASP A   104                                                      
REMARK 465     THR A   105                                                      
REMARK 465     PHE A   106                                                      
REMARK 465     VAL A   107                                                      
REMARK 465     THR A   108                                                      
REMARK 465     ARG A   109                                                      
REMARK 465     LYS A   110                                                      
REMARK 465     SER A   111                                                      
REMARK 465     ARG A   112                                                      
REMARK 465     LYS A   113                                                      
REMARK 465     ARG A   114                                                      
REMARK 465     ALA A   115                                                      
REMARK 465     LYS A   116                                                      
REMARK 465     LYS A   117                                                      
REMARK 465     MET A   118                                                      
REMARK 465     THR A   119                                                      
REMARK 465     LYS A   120                                                      
REMARK 465     LYS A   121                                                      
REMARK 465     ALA A   122                                                      
REMARK 465     LYS A   123                                                      
REMARK 465     ARG A   124                                                      
REMARK 465     SER A   125                                                      
REMARK 465     ASN A   126                                                      
REMARK 465     ARG A   358                                                      
REMARK 465     GLU A   359                                                      
REMARK 465     GLU A   360                                                      
REMARK 465     GLU A   361                                                      
REMARK 465     GLU A   362                                                      
REMARK 465     ASP A   363                                                      
REMARK 465     TYR A   364                                                      
REMARK 465     ASN A   365                                                      
REMARK 465     GLU A   366                                                      
REMARK 465     ASN A   429                                                      
REMARK 465     PRO A   430                                                      
REMARK 465     ILE A   431                                                      
REMARK 465     PRO A   432                                                      
REMARK 465     HIS A   433                                                      
REMARK 465     PHE A   434                                                      
REMARK 465     ILE A   435                                                      
REMARK 465     ASP A   436                                                      
REMARK 465     ASN A   437                                                      
REMARK 465     ASN A   438                                                      
REMARK 465     SER A   439                                                      
REMARK 465     SER A   440                                                      
REMARK 465     LEU A   441                                                      
REMARK 465     ASN A   442                                                      
REMARK 465     VAL A   443                                                      
REMARK 465     SER A   444                                                      
REMARK 465     ASN A   445                                                      
REMARK 465     THR A   446                                                      
REMARK 465     LYS A   447                                                      
REMARK 465     GLU A   448                                                      
REMARK 465     ASN A   449                                                      
REMARK 465     GLY A   450                                                      
REMARK 465     ASP A   451                                                      
REMARK 465     PHE A   452                                                      
REMARK 465     THR A   453                                                      
REMARK 465     LEU A   454                                                      
REMARK 465     PRO A   455                                                      
REMARK 465     GLU A  1576                                                      
REMARK 465     LYS A  1577                                                      
REMARK 465     ALA A  1578                                                      
REMARK 465     SER A  1579                                                      
REMARK 465     GLY A  1580                                                      
REMARK 465     PHE A  1581                                                      
REMARK 465     GLU A  1582                                                      
REMARK 465     ASP A  1583                                                      
REMARK 465     SER A  1584                                                      
REMARK 465     MET A  1585                                                      
REMARK 465     GLN A  1586                                                      
REMARK 465     PHE A  1587                                                      
REMARK 465     LYS A  1588                                                      
REMARK 465     LYS A  1589                                                      
REMARK 465     LEU A  1590                                                      
REMARK 465     THR A  1591                                                      
REMARK 465     HIS A  1592                                                      
REMARK 465     ALA A  1593                                                      
REMARK 465     GLN A  1594                                                      
REMARK 465     ARG A  1595                                                      
REMARK 465     THR A  1596                                                      
REMARK 465     GLY A  1597                                                      
REMARK 465     LEU A  1598                                                      
REMARK 465     SER A  1599                                                      
REMARK 465     LEU A  2101                                                      
REMARK 465     GLU A  2102                                                      
REMARK 465     ALA A  2103                                                      
REMARK 465     ALA A  2104                                                      
REMARK 465     ARG A  2105                                                      
REMARK 465     SER A  2106                                                      
REMARK 465     GLU A  2107                                                      
REMARK 465     LYS A  2108                                                      
REMARK 465     GLN A  2109                                                      
REMARK 465     ASN A  2110                                                      
REMARK 465     ASP A  2111                                                      
REMARK 465     GLU A  2112                                                      
REMARK 465     GLU A  2113                                                      
REMARK 465     ALA A  2114                                                      
REMARK 465     ALA A  2115                                                      
REMARK 465     GLY A  2116                                                      
REMARK 465     ALA A  2117                                                      
REMARK 465     SER A  2118                                                      
REMARK 465     THR A  2119                                                      
REMARK 465     VAL A  2120                                                      
REMARK 465     MET A  2121                                                      
REMARK 465     LYS A  2122                                                      
REMARK 465     THR A  2123                                                      
REMARK 465     LYS A  2124                                                      
REMARK 465     THR A  2125                                                      
REMARK 465     ILE A  2126                                                      
REMARK 465     ASN A  2127                                                      
REMARK 465     ALA A  2128                                                      
REMARK 465     GLN A  2129                                                      
REMARK 465     GLY A  2130                                                      
REMARK 465     GLU A  2131                                                      
REMARK 465     GLU A  2132                                                      
REMARK 465     ILE A  2133                                                      
REMARK 465     VAL A  2134                                                      
REMARK 465     VAL A  2135                                                      
REMARK 465     VAL A  2136                                                      
REMARK 465     ALA A  2137                                                      
REMARK 465     SER A  2138                                                      
REMARK 465     ALA A  2139                                                      
REMARK 465     ASP A  2140                                                      
REMARK 465     TYR A  2141                                                      
REMARK 465     GLU A  2142                                                      
REMARK 465     SER A  2143                                                      
REMARK 465     GLN A  2144                                                      
REMARK 465     THR A  2145                                                      
REMARK 465     PHE A  2146                                                      
REMARK 465     SER A  2147                                                      
REMARK 465     SER A  2148                                                      
REMARK 465     LYS A  2149                                                      
REMARK 465     ASN A  2150                                                      
REMARK 465     GLU A  2151                                                      
REMARK 465     TRP A  2152                                                      
REMARK 465     ARG A  2153                                                      
REMARK 465     LYS A  2154                                                      
REMARK 465     SER A  2155                                                      
REMARK 465     ALA A  2156                                                      
REMARK 465     ILE A  2157                                                      
REMARK 465     ALA A  2158                                                      
REMARK 465     ASN A  2159                                                      
REMARK 465     THR A  2160                                                      
REMARK 465     LEU A  2161                                                      
REMARK 465     LEU A  2162                                                      
REMARK 465     TYR A  2163                                                      
REMARK 465     LEU A  2164                                                      
REMARK 465     ARG A  2165                                                      
REMARK 465     LEU A  2166                                                      
REMARK 465     LYS A  2167                                                      
REMARK 465     ASN A  2168                                                      
REMARK 465     ILE A  2169                                                      
REMARK 465     TYR A  2170                                                      
REMARK 465     VAL A  2171                                                      
REMARK 465     SER A  2172                                                      
REMARK 465     ALA A  2173                                                      
REMARK 465     ASP A  2174                                                      
REMARK 465     ASP A  2175                                                      
REMARK 465     PHE A  2176                                                      
REMARK 465     VAL A  2177                                                      
REMARK 465     GLU A  2178                                                      
REMARK 465     GLU A  2179                                                      
REMARK 465     GLN A  2180                                                      
REMARK 465     ASN A  2181                                                      
REMARK 465     VAL A  2182                                                      
REMARK 465     TYR A  2183                                                      
REMARK 465     VAL A  2184                                                      
REMARK 465     LEU A  2185                                                      
REMARK 465     PRO A  2186                                                      
REMARK 465     LYS A  2187                                                      
REMARK 465     ASN A  2188                                                      
REMARK 465     LEU A  2189                                                      
REMARK 465     LEU A  2190                                                      
REMARK 465     LYS A  2191                                                      
REMARK 465     LYS A  2192                                                      
REMARK 465     PHE A  2193                                                      
REMARK 465     ILE A  2194                                                      
REMARK 465     GLU A  2195                                                      
REMARK 465     ILE A  2196                                                      
REMARK 465     SER A  2197                                                      
REMARK 465     ASP A  2198                                                      
REMARK 465     VAL A  2199                                                      
REMARK 465     LYS A  2200                                                      
REMARK 465     ILE A  2201                                                      
REMARK 465     GLN A  2202                                                      
REMARK 465     VAL A  2203                                                      
REMARK 465     ALA A  2204                                                      
REMARK 465     ALA A  2205                                                      
REMARK 465     PHE A  2206                                                      
REMARK 465     ILE A  2207                                                      
REMARK 465     TYR A  2208                                                      
REMARK 465     GLY A  2209                                                      
REMARK 465     MET A  2210                                                      
REMARK 465     SER A  2211                                                      
REMARK 465     ALA A  2212                                                      
REMARK 465     LYS A  2213                                                      
REMARK 465     ASP A  2214                                                      
REMARK 465     HIS A  2215                                                      
REMARK 465     PRO A  2216                                                      
REMARK 465     LYS A  2217                                                      
REMARK 465     VAL A  2218                                                      
REMARK 465     LYS A  2219                                                      
REMARK 465     GLU A  2220                                                      
REMARK 465     ILE A  2221                                                      
REMARK 465     LYS A  2222                                                      
REMARK 465     THR A  2223                                                      
REMARK 465     VAL A  2224                                                      
REMARK 465     VAL A  2225                                                      
REMARK 465     LEU A  2226                                                      
REMARK 465     VAL A  2227                                                      
REMARK 465     PRO A  2228                                                      
REMARK 465     GLN A  2229                                                      
REMARK 465     LEU A  2230                                                      
REMARK 465     GLY A  2231                                                      
REMARK 465     HIS A  2232                                                      
REMARK 465     VAL A  2233                                                      
REMARK 465     GLY A  2234                                                      
REMARK 465     SER A  2235                                                      
REMARK 465     VAL A  2236                                                      
REMARK 465     GLN A  2237                                                      
REMARK 465     ILE A  2238                                                      
REMARK 465     SER A  2239                                                      
REMARK 465     ASN A  2240                                                      
REMARK 465     ILE A  2241                                                      
REMARK 465     PRO A  2242                                                      
REMARK 465     ASP A  2243                                                      
REMARK 465     ILE A  2244                                                      
REMARK 465     GLY A  2245                                                      
REMARK 465     ASP A  2246                                                      
REMARK 465     LEU A  2247                                                      
REMARK 465     PRO A  2248                                                      
REMARK 465     ASP A  2249                                                      
REMARK 465     THR A  2250                                                      
REMARK 465     GLU A  2251                                                      
REMARK 465     GLY A  2252                                                      
REMARK 465     LEU A  2253                                                      
REMARK 465     GLU A  2254                                                      
REMARK 465     LEU A  2255                                                      
REMARK 465     LEU A  2256                                                      
REMARK 465     GLY A  2257                                                      
REMARK 465     TRP A  2258                                                      
REMARK 465     ILE A  2259                                                      
REMARK 465     HIS A  2260                                                      
REMARK 465     THR A  2261                                                      
REMARK 465     GLN A  2262                                                      
REMARK 465     THR A  2263                                                      
REMARK 465     GLU A  2264                                                      
REMARK 465     GLU A  2265                                                      
REMARK 465     LEU A  2266                                                      
REMARK 465     LYS A  2267                                                      
REMARK 465     PHE A  2268                                                      
REMARK 465     MET A  2269                                                      
REMARK 465     ALA A  2270                                                      
REMARK 465     ALA A  2271                                                      
REMARK 465     SER A  2272                                                      
REMARK 465     GLU A  2273                                                      
REMARK 465     VAL A  2274                                                      
REMARK 465     ALA A  2275                                                      
REMARK 465     THR A  2276                                                      
REMARK 465     HIS A  2277                                                      
REMARK 465     SER A  2278                                                      
REMARK 465     LYS A  2279                                                      
REMARK 465     LEU A  2280                                                      
REMARK 465     PHE A  2281                                                      
REMARK 465     ALA A  2282                                                      
REMARK 465     ASP A  2283                                                      
REMARK 465     LYS A  2284                                                      
REMARK 465     LYS A  2285                                                      
REMARK 465     ARG A  2286                                                      
REMARK 465     ASP A  2287                                                      
REMARK 465     CYS A  2288                                                      
REMARK 465     ILE A  2289                                                      
REMARK 465     ASP A  2290                                                      
REMARK 465     ILE A  2291                                                      
REMARK 465     SER A  2292                                                      
REMARK 465     ILE A  2293                                                      
REMARK 465     PHE A  2294                                                      
REMARK 465     SER A  2295                                                      
REMARK 465     THR A  2296                                                      
REMARK 465     PRO A  2297                                                      
REMARK 465     GLY A  2298                                                      
REMARK 465     SER A  2299                                                      
REMARK 465     VAL A  2300                                                      
REMARK 465     SER A  2301                                                      
REMARK 465     LEU A  2302                                                      
REMARK 465     SER A  2303                                                      
REMARK 465     ALA A  2304                                                      
REMARK 465     TYR A  2305                                                      
REMARK 465     ASN A  2306                                                      
REMARK 465     LEU A  2307                                                      
REMARK 465     THR A  2308                                                      
REMARK 465     ASP A  2309                                                      
REMARK 465     GLU A  2310                                                      
REMARK 465     GLY A  2311                                                      
REMARK 465     TYR A  2312                                                      
REMARK 465     GLN A  2313                                                      
REMARK 465     TRP A  2314                                                      
REMARK 465     GLY A  2315                                                      
REMARK 465     GLU A  2316                                                      
REMARK 465     GLU A  2317                                                      
REMARK 465     ASN A  2318                                                      
REMARK 465     LYS A  2319                                                      
REMARK 465     ASP A  2320                                                      
REMARK 465     ILE A  2321                                                      
REMARK 465     MET A  2322                                                      
REMARK 465     ASN A  2323                                                      
REMARK 465     VAL A  2324                                                      
REMARK 465     LEU A  2325                                                      
REMARK 465     SER A  2326                                                      
REMARK 465     GLU A  2327                                                      
REMARK 465     GLY A  2328                                                      
REMARK 465     PHE A  2329                                                      
REMARK 465     GLU A  2330                                                      
REMARK 465     PRO A  2331                                                      
REMARK 465     THR A  2332                                                      
REMARK 465     PHE A  2333                                                      
REMARK 465     SER A  2334                                                      
REMARK 465     THR A  2335                                                      
REMARK 465     HIS A  2336                                                      
REMARK 465     ALA A  2337                                                      
REMARK 465     GLN A  2338                                                      
REMARK 465     LEU A  2339                                                      
REMARK 465     LEU A  2340                                                      
REMARK 465     LEU A  2341                                                      
REMARK 465     SER A  2342                                                      
REMARK 465     ASP A  2343                                                      
REMARK 465     ARG A  2344                                                      
REMARK 465     ILE A  2345                                                      
REMARK 465     THR A  2346                                                      
REMARK 465     GLY A  2347                                                      
REMARK 465     ASN A  2348                                                      
REMARK 465     PHE A  2349                                                      
REMARK 465     ILE A  2350                                                      
REMARK 465     ILE A  2351                                                      
REMARK 465     PRO A  2352                                                      
REMARK 465     SER A  2353                                                      
REMARK 465     GLY A  2354                                                      
REMARK 465     ASN A  2355                                                      
REMARK 465     VAL A  2356                                                      
REMARK 465     TRP A  2357                                                      
REMARK 465     ASN A  2358                                                      
REMARK 465     TYR A  2359                                                      
REMARK 465     THR A  2360                                                      
REMARK 465     PHE A  2361                                                      
REMARK 465     MET A  2362                                                      
REMARK 465     GLY A  2363                                                      
REMARK 465     THR A  2364                                                      
REMARK 465     ALA A  2365                                                      
REMARK 465     PHE A  2366                                                      
REMARK 465     ASN A  2367                                                      
REMARK 465     GLN A  2368                                                      
REMARK 465     GLU A  2369                                                      
REMARK 465     GLY A  2370                                                      
REMARK 465     ASP A  2371                                                      
REMARK 465     TYR A  2372                                                      
REMARK 465     ASN A  2373                                                      
REMARK 465     PHE A  2374                                                      
REMARK 465     LYS A  2375                                                      
REMARK 465     TYR A  2376                                                      
REMARK 465     GLY A  2377                                                      
REMARK 465     ILE A  2378                                                      
REMARK 465     PRO A  2379                                                      
REMARK 465     LEU A  2380                                                      
REMARK 465     GLU A  2381                                                      
REMARK 465     PHE A  2382                                                      
REMARK 465     TYR A  2383                                                      
REMARK 465     ASN A  2384                                                      
REMARK 465     GLU A  2385                                                      
REMARK 465     MET A  2386                                                      
REMARK 465     HIS A  2387                                                      
REMARK 465     ARG A  2388                                                      
REMARK 465     PRO A  2389                                                      
REMARK 465     VAL A  2390                                                      
REMARK 465     HIS A  2391                                                      
REMARK 465     PHE A  2392                                                      
REMARK 465     LEU A  2393                                                      
REMARK 465     GLN A  2394                                                      
REMARK 465     PHE A  2395                                                      
REMARK 465     SER A  2396                                                      
REMARK 465     GLU A  2397                                                      
REMARK 465     LEU A  2398                                                      
REMARK 465     ALA A  2399                                                      
REMARK 465     GLY A  2400                                                      
REMARK 465     ASP A  2401                                                      
REMARK 465     GLU A  2402                                                      
REMARK 465     GLU A  2403                                                      
REMARK 465     LEU A  2404                                                      
REMARK 465     GLU A  2405                                                      
REMARK 465     ALA A  2406                                                      
REMARK 465     GLU A  2407                                                      
REMARK 465     GLN A  2408                                                      
REMARK 465     ILE A  2409                                                      
REMARK 465     ASP A  2410                                                      
REMARK 465     VAL A  2411                                                      
REMARK 465     PHE A  2412                                                      
REMARK 465     SER A  2413                                                      
REMARK 465     MET C     1                                                      
REMARK 465     GLU C     2                                                      
REMARK 465     GLY C     3                                                      
REMARK 465     ASP C     4                                                      
REMARK 465     ASP C     5                                                      
REMARK 465     LEU C     6                                                      
REMARK 465     PHE C     7                                                      
REMARK 465     ASP C     8                                                      
REMARK 465     GLU C     9                                                      
REMARK 465     PHE C    10                                                      
REMARK 465     GLY C    11                                                      
REMARK 465     ASN C    12                                                      
REMARK 465     LEU C    13                                                      
REMARK 465     ILE C    14                                                      
REMARK 465     GLY C    15                                                      
REMARK 465     VAL C    16                                                      
REMARK 465     ASP C    17                                                      
REMARK 465     PRO C    18                                                      
REMARK 465     PHE C    19                                                      
REMARK 465     ASP C    20                                                      
REMARK 465     SER C    21                                                      
REMARK 465     ASP C    22                                                      
REMARK 465     GLU C    23                                                      
REMARK 465     GLU C    24                                                      
REMARK 465     GLU C    25                                                      
REMARK 465     SER C    26                                                      
REMARK 465     VAL C    27                                                      
REMARK 465     LEU C    28                                                      
REMARK 465     ASP C    29                                                      
REMARK 465     GLU C    30                                                      
REMARK 465     GLN C    31                                                      
REMARK 465     GLU C    32                                                      
REMARK 465     GLN C    33                                                      
REMARK 465     TYR C    34                                                      
REMARK 465     GLN C    35                                                      
REMARK 465     THR C    36                                                      
REMARK 465     ASN C    37                                                      
REMARK 465     THR C    38                                                      
REMARK 465     PHE C    39                                                      
REMARK 465     GLU C    40                                                      
REMARK 465     GLY C    41                                                      
REMARK 465     SER C    42                                                      
REMARK 465     GLY C    43                                                      
REMARK 465     ASN C    44                                                      
REMARK 465     ASN C    45                                                      
REMARK 465     ASN C    46                                                      
REMARK 465     GLU C    47                                                      
REMARK 465     ILE C    48                                                      
REMARK 465     GLU C    49                                                      
REMARK 465     SER C    50                                                      
REMARK 465     ARG C    51                                                      
REMARK 465     GLN C    52                                                      
REMARK 465     LEU C    53                                                      
REMARK 465     THR C    54                                                      
REMARK 465     SER C    55                                                      
REMARK 465     LEU C    56                                                      
REMARK 465     GLY C    57                                                      
REMARK 465     SER C    58                                                      
REMARK 465     LYS C    59                                                      
REMARK 465     LYS C    60                                                      
REMARK 465     GLU C    61                                                      
REMARK 465     LEU C    62                                                      
REMARK 465     GLY C    63                                                      
REMARK 465     ILE C    64                                                      
REMARK 465     SER C    65                                                      
REMARK 465     LEU C    66                                                      
REMARK 465     GLU C    67                                                      
REMARK 465     HIS C    68                                                      
REMARK 465     PRO C    69                                                      
REMARK 465     TYR C    70                                                      
REMARK 465     GLY C    71                                                      
REMARK 465     LYS C    72                                                      
REMARK 465     HIS C   516                                                      
REMARK 465     ASP C   517                                                      
REMARK 465     ILE C   518                                                      
REMARK 465     SER C   519                                                      
REMARK 465     LYS C   520                                                      
REMARK 465     THR C   521                                                      
REMARK 465     GLU C   522                                                      
REMARK 465     THR C   523                                                      
REMARK 465     SER C   524                                                      
REMARK 465     ASN C   525                                                      
REMARK 465     GLU C   526                                                      
REMARK 465     ASP C   527                                                      
REMARK 465     GLU C   528                                                      
REMARK 465     ASP C   529                                                      
REMARK 465     GLU C   530                                                      
REMARK 465     ASP C   531                                                      
REMARK 465     SER C   694                                                      
REMARK 465     ILE C   695                                                      
REMARK 465     SER C   696                                                      
REMARK 465     ARG C   697                                                      
REMARK 465     LEU C   698                                                      
REMARK 465     GLY C   699                                                      
REMARK 465     GLU C   700                                                      
REMARK 465     GLU C   701                                                      
REMARK 465     ASN C   702                                                      
REMARK 465     LEU C   703                                                      
REMARK 465     PRO C   704                                                      
REMARK 465     GLY C   705                                                      
REMARK 465     LEU C   706                                                      
REMARK 465     SER C   707                                                      
REMARK 465     ASN C   726                                                      
REMARK 465     THR C   727                                                      
REMARK 465     LEU C   728                                                      
REMARK 465     GLY C   729                                                      
REMARK 465     LYS C   730                                                      
REMARK 465     GLY C   731                                                      
REMARK 465     GLN C   732                                                      
REMARK 465     ASN C   733                                                      
REMARK 465     CYS C   734                                                      
REMARK 465     LEU C   735                                                      
REMARK 465     ASP C   736                                                      
REMARK 465     ILE C   737                                                      
REMARK 465     ASP C   738                                                      
REMARK 465     GLY C   739                                                      
REMARK 465     ILE C   740                                                      
REMARK 465     MET C   741                                                      
REMARK 465     ASP C   742                                                      
REMARK 465     ASN C   743                                                      
REMARK 465     ASN C   769A                                                     
REMARK 465     GLY C   769B                                                     
REMARK 465     ASN C   769C                                                     
REMARK 465     TYR C   998                                                      
REMARK 465     ALA C   999                                                      
REMARK 465     GLN C  1000                                                      
REMARK 465     LEU C  1001                                                      
REMARK 465     ARG C  1002                                                      
REMARK 465     GLU C  1003                                                      
REMARK 465     ASN C  1004                                                      
REMARK 465     GLY C  1005                                                      
REMARK 465     LEU C  1006                                                      
REMARK 465     VAL C  1007                                                      
REMARK 465     PRO C  1008                                                      
REMARK 465     MET H     1                                                      
REMARK 465     SER H     2                                                      
REMARK 465     THR H     3                                                      
REMARK 465     ALA H     4                                                      
REMARK 465     THR H     5                                                      
REMARK 465     ILE H     6                                                      
REMARK 465     GLN H     7                                                      
REMARK 465     ASP H     8                                                      
REMARK 465     GLU H     9                                                      
REMARK 465     ASP H    10                                                      
REMARK 465     GLY H   208                                                      
REMARK 465     SER H   209                                                      
REMARK 465     GLN H   210                                                      
REMARK 465     GLY H   211                                                      
REMARK 465     LEU H   212                                                      
REMARK 465     PHE H   213                                                      
REMARK 465     ILE H   214                                                      
REMARK 465     LEU H   215                                                      
REMARK 465     ASP H   216                                                      
REMARK 465     PRO H   217                                                      
REMARK 465     THR H   218                                                      
REMARK 465     SER H   219                                                      
REMARK 465     TYR H   220                                                      
REMARK 465     THR H   221                                                      
REMARK 465     VAL H   222                                                      
REMARK 465     HIS H   223                                                      
REMARK 465     THR H   224                                                      
REMARK 465     HIS H   225                                                      
REMARK 465     SER H   226                                                      
REMARK 465     TYR H   227                                                      
REMARK 465     ILE H   228                                                      
REMARK 465     VAL H   229                                                      
REMARK 465     SER H   230                                                      
REMARK 465     ASP H   231                                                      
REMARK 465     GLU H   232                                                      
REMARK 465     ASP H   233                                                      
REMARK 465     GLU H   234                                                      
REMARK 465     ALA H   235                                                      
REMARK 465     ASN H   236                                                      
REMARK 465     LYS H   237                                                      
REMARK 465     GLU H   238                                                      
REMARK 465     LEU H   239                                                      
REMARK 465     GLY H   240                                                      
REMARK 465     ASN H   241                                                      
REMARK 465     PHE H   242                                                      
REMARK 465     GLU H   243                                                      
REMARK 465     LYS H   244                                                      
REMARK 465     LEU H   263                                                      
REMARK 465     ILE H   264                                                      
REMARK 465     ASN H   265                                                      
REMARK 465     ASN H   266                                                      
REMARK 465     THR H   267                                                      
REMARK 465     SER H   268                                                      
REMARK 465     ASP H   269                                                      
REMARK 465     THR H   270                                                      
REMARK 465     ASN H   271                                                      
REMARK 465     GLU H   272                                                      
REMARK 465     GLY H   273                                                      
REMARK 465     SER H   274                                                      
REMARK 465     ASN H   275                                                      
REMARK 465     SER H   276                                                      
REMARK 465     GLN H   277                                                      
REMARK 465     LEU H   278                                                      
REMARK 465     GLN H   279                                                      
REMARK 465     ILE H   280                                                      
REMARK 465     TYR H   281                                                      
REMARK 465     ASP H   282                                                      
REMARK 465     MET H   283                                                      
REMARK 465     THR H   284                                                      
REMARK 465     SER H   285                                                      
REMARK 465     THR H   286                                                      
REMARK 465     ASN H   287                                                      
REMARK 465     ASP H   288                                                      
REMARK 465     LYS H   403                                                      
REMARK 465     ILE H   404                                                      
REMARK 465     ILE H   405                                                      
REMARK 465     LYS H   406                                                      
REMARK 465     LEU H   407                                                      
REMARK 465     THR H   408                                                      
REMARK 465     GLU H   409                                                      
REMARK 465     THR H   482                                                      
REMARK 465     ILE H   483                                                      
REMARK 465     ILE H   484                                                      
REMARK 465     GLN H   485                                                      
REMARK 465     GLU H   486                                                      
REMARK 465     VAL H   487                                                      
REMARK 465     GLU H   488                                                      
REMARK 465     ASP H   489                                                      
REMARK 465     ALA H   490                                                      
REMARK 465     GLU H   491                                                      
REMARK 465     GLU H   492                                                      
REMARK 465     GLU H   493                                                      
REMARK 465     GLU H   494                                                      
REMARK 465     LYS H   495                                                      
REMARK 465     LYS H   496                                                      
REMARK 465     LEU H   497                                                      
REMARK 465     ARG H   498                                                      
REMARK 465     GLU H   499                                                      
REMARK 465     GLU H   500                                                      
REMARK 465     GLU H   501                                                      
REMARK 465     GLU H   502                                                      
REMARK 465     LEU H   503                                                      
REMARK 465     GLU H   504                                                      
REMARK 465     LYS H   505                                                      
REMARK 465     LEU H   506                                                      
REMARK 465     ARG H   507                                                      
REMARK 465     LYS H   508                                                      
REMARK 465     LYS H   509                                                      
REMARK 465     ALA H   510                                                      
REMARK 465     ARG H   511                                                      
REMARK 465     GLU H   512                                                      
REMARK 465     SER H   513                                                      
REMARK 465     GLN H   514                                                      
REMARK 465     PRO H   515                                                      
REMARK 465     THR H   516                                                      
REMARK 465     GLN H   517                                                      
REMARK 465     GLY H   518                                                      
REMARK 465     PRO H   519                                                      
REMARK 465     LYS H   520                                                      
REMARK 465     ILE H   521                                                      
REMARK 465     HIS H   522                                                      
REMARK 465     GLU H   523                                                      
REMARK 465     SER H   524                                                      
REMARK 465     ARG H   525                                                      
REMARK 465     LEU H   526                                                      
REMARK 465     PHE H   527                                                      
REMARK 465     LEU H   528                                                      
REMARK 465     GLN H   529                                                      
REMARK 465     LYS H   530                                                      
REMARK 465     ASP H   531                                                      
REMARK 465     THR H   532                                                      
REMARK 465     ARG H   533                                                      
REMARK 465     GLU H   534                                                      
REMARK 465     ASN H   535                                                      
REMARK 465     SER H   536                                                      
REMARK 465     ARG H   537                                                      
REMARK 465     SER H   538                                                      
REMARK 465     ARG H   539                                                      
REMARK 465     SER H   540                                                      
REMARK 465     PRO H   541                                                      
REMARK 465     PHE H   542                                                      
REMARK 465     THR H   543                                                      
REMARK 465     VAL H   544                                                      
REMARK 465     GLU H   545                                                      
REMARK 465     THR H   546                                                      
REMARK 465     ARG H   547                                                      
REMARK 465     LYS H   548                                                      
REMARK 465     ARG H   549                                                      
REMARK 465     ALA H   550                                                      
REMARK 465     ARG H   551                                                      
REMARK 465     SER H   552                                                      
REMARK 465     ARG H   553                                                      
REMARK 465     THR H   554                                                      
REMARK 465     PRO H   555                                                      
REMARK 465     PRO H   556                                                      
REMARK 465     ARG H   557                                                      
REMARK 465     GLY H   558                                                      
REMARK 465     SER H   559                                                      
REMARK 465     ARG H   560                                                      
REMARK 465     ASN H   561                                                      
REMARK 465     HIS H   562                                                      
REMARK 465     ARG H   563                                                      
REMARK 465     ASN H   564                                                      
REMARK 465     ARG H   565                                                      
REMARK 465     SER H   566                                                      
REMARK 465     ARG H   567                                                      
REMARK 465     THR H   568                                                      
REMARK 465     PRO H   569                                                      
REMARK 465     PRO H   570                                                      
REMARK 465     ALA H   571                                                      
REMARK 465     ARG H   572                                                      
REMARK 465     ARG H   573                                                      
REMARK 465     GLN H   574                                                      
REMARK 465     ARG H   575                                                      
REMARK 465     HIS H   576                                                      
REMARK 465     ARG H   577                                                      
REMARK 465     MET J     1                                                      
REMARK 465     ASP J     2                                                      
REMARK 465     GLY J     3                                                      
REMARK 465     ASN J     4                                                      
REMARK 465     ASP J     5                                                      
REMARK 465     HIS J     6                                                      
REMARK 465     LYS J     7                                                      
REMARK 465     VAL J     8                                                      
REMARK 465     GLU J     9                                                      
REMARK 465     ASN J    10                                                      
REMARK 465     LEU J    11                                                      
REMARK 465     GLY J    12                                                      
REMARK 465     ASP J    13                                                      
REMARK 465     VAL J    14                                                      
REMARK 465     ASP J    15                                                      
REMARK 465     LYS J    16                                                      
REMARK 465     PHE J    17                                                      
REMARK 465     TYR J    18                                                      
REMARK 465     SER J    19                                                      
REMARK 465     ARG J    20                                                      
REMARK 465     ILE J    21                                                      
REMARK 465     ARG J    22                                                      
REMARK 465     TRP J    23                                                      
REMARK 465     ASN J    24                                                      
REMARK 465     ASN J    25                                                      
REMARK 465     GLN J    26                                                      
REMARK 465     PHE J    27                                                      
REMARK 465     SER J    28                                                      
REMARK 465     TYR J    29                                                      
REMARK 465     MET J    30                                                      
REMARK 465     ALA J    31                                                      
REMARK 465     THR J    32                                                      
REMARK 465     LEU J    33                                                      
REMARK 465     PRO J    34                                                      
REMARK 465     PRO J    35                                                      
REMARK 465     HIS J    36                                                      
REMARK 465     LEU J    37                                                      
REMARK 465     GLN J    38                                                      
REMARK 465     SER J    39                                                      
REMARK 465     GLU J    40                                                      
REMARK 465     MET J    41                                                      
REMARK 465     GLU J    42                                                      
REMARK 465     GLY J    43                                                      
REMARK 465     GLN J    44                                                      
REMARK 465     LYS J    45                                                      
REMARK 465     SER J    46                                                      
REMARK 465     LEU J    47                                                      
REMARK 465     LEU J    48                                                      
REMARK 465     MET J    49                                                      
REMARK 465     ARG J    50                                                      
REMARK 465     TYR J    51                                                      
REMARK 465     ASP J    52                                                      
REMARK 465     THR J    53                                                      
REMARK 465     TYR J    54                                                      
REMARK 465     ARG J    55                                                      
REMARK 465     LYS J    56                                                      
REMARK 465     GLU J    57                                                      
REMARK 465     SER J    58                                                      
REMARK 465     SER J    59                                                      
REMARK 465     SER J    60                                                      
REMARK 465     PHE J    61                                                      
REMARK 465     SER J    62                                                      
REMARK 465     GLY J    63                                                      
REMARK 465     GLU J    64                                                      
REMARK 465     GLY J    65                                                      
REMARK 465     LYS J    66                                                      
REMARK 465     LYS J    67                                                      
REMARK 465     VAL J    68                                                      
REMARK 465     THR J    69                                                      
REMARK 465     LEU J    70                                                      
REMARK 465     GLN J    71                                                      
REMARK 465     HIS J    72                                                      
REMARK 465     VAL J    73                                                      
REMARK 465     PRO J    74                                                      
REMARK 465     THR J    75                                                      
REMARK 465     ASP J    76                                                      
REMARK 465     PHE J    77                                                      
REMARK 465     SER J    78                                                      
REMARK 465     GLU J    79                                                      
REMARK 465     ALA J    80                                                      
REMARK 465     SER J    81                                                      
REMARK 465     GLN J    82                                                      
REMARK 465     ALA J    83                                                      
REMARK 465     VAL J    84                                                      
REMARK 465     ILE J    85                                                      
REMARK 465     SER J    86                                                      
REMARK 465     LYS J    87                                                      
REMARK 465     LYS J    88                                                      
REMARK 465     ASP J    89                                                      
REMARK 465     HIS J    90                                                      
REMARK 465     ASP J    91                                                      
REMARK 465     THR J    92                                                      
REMARK 465     HIS J    93                                                      
REMARK 465     ALA J    94                                                      
REMARK 465     SER J    95                                                      
REMARK 465     ALA J    96                                                      
REMARK 465     PHE J    97                                                      
REMARK 465     VAL J    98                                                      
REMARK 465     ASN J    99                                                      
REMARK 465     LYS J   100                                                      
REMARK 465     ILE J   101                                                      
REMARK 465     PHE J   102                                                      
REMARK 465     GLN J   103                                                      
REMARK 465     PRO J   104                                                      
REMARK 465     GLU J   105                                                      
REMARK 465     VAL J   106                                                      
REMARK 465     ALA J   107                                                      
REMARK 465     GLU J   108                                                      
REMARK 465     GLU J   109                                                      
REMARK 465     MET K     1                                                      
REMARK 465     PHE K     2                                                      
REMARK 465     SER K     3                                                      
REMARK 465     ASN K     4                                                      
REMARK 465     ARG K     5                                                      
REMARK 465     LEU K     6                                                      
REMARK 465     PRO K     7                                                      
REMARK 465     PRO K     8                                                      
REMARK 465     PRO K     9                                                      
REMARK 465     LYS K    10                                                      
REMARK 465     HIS K    11                                                      
REMARK 465     SER K    12                                                      
REMARK 465     GLN K    13                                                      
REMARK 465     GLY K    14                                                      
REMARK 465     ARG K    15                                                      
REMARK 465     VAL K    16                                                      
REMARK 465     SER K    17                                                      
REMARK 465     THR K    18                                                      
REMARK 465     ALA K    19                                                      
REMARK 465     LEU K    20                                                      
REMARK 465     SER K    21                                                      
REMARK 465     SER K    22                                                      
REMARK 465     ASP K    23                                                      
REMARK 465     ARG K    24                                                      
REMARK 465     VAL K    25                                                      
REMARK 465     GLU K    26                                                      
REMARK 465     PRO K    27                                                      
REMARK 465     ALA K    28                                                      
REMARK 465     ILE K    29                                                      
REMARK 465     LEU K    30                                                      
REMARK 465     GLU K    96                                                      
REMARK 465     THR K    97                                                      
REMARK 465     HIS K    98                                                      
REMARK 465     GLN K    99                                                      
REMARK 465     ALA K   100                                                      
REMARK 465     PRO K   101                                                      
REMARK 465     ALA K   102                                                      
REMARK 465     ASN K   103                                                      
REMARK 465     LYS K   226                                                      
REMARK 465     ARG K   227                                                      
REMARK 465     LEU K   228                                                      
REMARK 465     ALA K   229                                                      
REMARK 465     MET K   230                                                      
REMARK 465     GLU K   231                                                      
REMARK 465     GLN K   232                                                      
REMARK 465     GLU K   233                                                      
REMARK 465     MET K   234                                                      
REMARK 465     LEU K   235                                                      
REMARK 465     ALA K   236                                                      
REMARK 465     LYS K   237                                                      
REMARK 465     GLU K   238                                                      
REMARK 465     SER K   239                                                      
REMARK 465     LYS K   240                                                      
REMARK 465     LEU K   241                                                      
REMARK 465     LYS K   242                                                      
REMARK 465     GLU K   243                                                      
REMARK 465     LEU K   244                                                      
REMARK 465     SER K   245                                                      
REMARK 465     GLN K   246                                                      
REMARK 465     ARG K   247                                                      
REMARK 465     ALA K   248                                                      
REMARK 465     ARG K   249                                                      
REMARK 465     TYR K   250                                                      
REMARK 465     HIS K   251                                                      
REMARK 465     ASN K   252                                                      
REMARK 465     GLY K   253                                                      
REMARK 465     THR K   254                                                      
REMARK 465     PRO K   255                                                      
REMARK 465     GLN K   256                                                      
REMARK 465     THR K   257                                                      
REMARK 465     GLY K   258                                                      
REMARK 465     ALA K   259                                                      
REMARK 465     ILE K   260                                                      
REMARK 465     VAL K   261                                                      
REMARK 465     LYS K   262                                                      
REMARK 465     PRO K   263                                                      
REMARK 465     LYS K   264                                                      
REMARK 465     LYS K   265                                                      
REMARK 465     GLN K   266                                                      
REMARK 465     THR K   267                                                      
REMARK 465     SER K   268                                                      
REMARK 465     THR K   269                                                      
REMARK 465     VAL K   270                                                      
REMARK 465     ALA K   271                                                      
REMARK 465     ARG K   272                                                      
REMARK 465     LEU K   273                                                      
REMARK 465     LYS K   274                                                      
REMARK 465     GLU K   275                                                      
REMARK 465     LEU K   276                                                      
REMARK 465     ALA K   277                                                      
REMARK 465     TYR K   278                                                      
REMARK 465     SER K   279                                                      
REMARK 465     GLN K   280                                                      
REMARK 465     GLY K   281                                                      
REMARK 465     ARG K   282                                                      
REMARK 465     ASP K   283                                                      
REMARK 465     VAL K   284                                                      
REMARK 465     SER K   285                                                      
REMARK 465     GLU K   286                                                      
REMARK 465     LYS K   287                                                      
REMARK 465     ILE K   288                                                      
REMARK 465     ILE K   289                                                      
REMARK 465     LEU K   290                                                      
REMARK 465     GLY K   291                                                      
REMARK 465     ALA K   292                                                      
REMARK 465     ALA K   293                                                      
REMARK 465     LYS K   294                                                      
REMARK 465     ARG K   295                                                      
REMARK 465     SER K   296                                                      
REMARK 465     GLU K   297                                                      
REMARK 465     GLN K   298                                                      
REMARK 465     PRO K   299                                                      
REMARK 465     ASP K   300                                                      
REMARK 465     LEU K   301                                                      
REMARK 465     GLN K   302                                                      
REMARK 465     TYR K   303                                                      
REMARK 465     ASP K   304                                                      
REMARK 465     SER K   305                                                      
REMARK 465     ARG K   306                                                      
REMARK 465     PHE K   307                                                      
REMARK 465     PHE K   308                                                      
REMARK 465     THR K   309                                                      
REMARK 465     ARG K   310                                                      
REMARK 465     GLY K   311                                                      
REMARK 465     ALA K   312                                                      
REMARK 465     ASN K   313                                                      
REMARK 465     ALA K   314                                                      
REMARK 465     SER K   315                                                      
REMARK 465     ALA K   316                                                      
REMARK 465     LYS K   317                                                      
REMARK 465     ARG K   318                                                      
REMARK 465     HIS K   319                                                      
REMARK 465     GLU K   320                                                      
REMARK 465     ASP K   321                                                      
REMARK 465     GLN K   322                                                      
REMARK 465     VAL K   323                                                      
REMARK 465     TYR K   324                                                      
REMARK 465     ASP K   325                                                      
REMARK 465     ASN K   326                                                      
REMARK 465     PRO K   327                                                      
REMARK 465     LEU K   328                                                      
REMARK 465     PHE K   329                                                      
REMARK 465     VAL K   330                                                      
REMARK 465     GLN K   331                                                      
REMARK 465     GLN K   332                                                      
REMARK 465     ASP K   333                                                      
REMARK 465     ILE K   334                                                      
REMARK 465     GLU K   335                                                      
REMARK 465     SER K   336                                                      
REMARK 465     ILE K   337                                                      
REMARK 465     TYR K   338                                                      
REMARK 465     LYS K   339                                                      
REMARK 465     THR K   340                                                      
REMARK 465     ASN K   341                                                      
REMARK 465     TYR K   342                                                      
REMARK 465     GLU K   343                                                      
REMARK 465     LYS K   344                                                      
REMARK 465     LEU K   345                                                      
REMARK 465     ASP K   346                                                      
REMARK 465     GLU K   347                                                      
REMARK 465     ALA K   348                                                      
REMARK 465     VAL K   349                                                      
REMARK 465     ASN K   350                                                      
REMARK 465     VAL K   351                                                      
REMARK 465     LYS K   352                                                      
REMARK 465     SER K   353                                                      
REMARK 465     GLU K   354                                                      
REMARK 465     GLY K   355                                                      
REMARK 465     ALA K   356                                                      
REMARK 465     SER K   357                                                      
REMARK 465     GLY K   358                                                      
REMARK 465     SER K   359                                                      
REMARK 465     HIS K   360                                                      
REMARK 465     GLY K   361                                                      
REMARK 465     PRO K   362                                                      
REMARK 465     ILE K   363                                                      
REMARK 465     GLN K   364                                                      
REMARK 465     PHE K   365                                                      
REMARK 465     THR K   366                                                      
REMARK 465     LYS K   367                                                      
REMARK 465     ALA K   368                                                      
REMARK 465     GLU K   369                                                      
REMARK 465     SER K   370                                                      
REMARK 465     ASP K   371                                                      
REMARK 465     ASP K   372                                                      
REMARK 465     LYS K   373                                                      
REMARK 465     SER K   374                                                      
REMARK 465     ASP K   375                                                      
REMARK 465     ASN K   376                                                      
REMARK 465     TYR K   377                                                      
REMARK 465     GLY K   378                                                      
REMARK 465     ALA K   379                                                      
REMARK 465     MET L     1                                                      
REMARK 465     ASP L   157                                                      
REMARK 465     MET M     1                                                      
REMARK 465     THR M     2                                                      
REMARK 465     ASN M   255                                                      
REMARK 465     ASN M   256                                                      
REMARK 465     ASN M   257                                                      
REMARK 465     THR M   258                                                      
REMARK 465     ASN M   259                                                      
REMARK 465     SER M   260                                                      
REMARK 465     ALA M   261                                                      
REMARK 465     GLY M   262                                                      
REMARK 465     THR M   263                                                      
REMARK 465     GLU M   264                                                      
REMARK 465     VAL M   265                                                      
REMARK 465     ASN M   266                                                      
REMARK 465     ASN M   267                                                      
REMARK 465     LYS M   268                                                      
REMARK 465     ASN M   269                                                      
REMARK 465     ASN M   270                                                      
REMARK 465     GLU M   271                                                      
REMARK 465     ARG M   272                                                      
REMARK 465     LEU M   273                                                      
REMARK 465     ASP M   274                                                      
REMARK 465     ARG M   275                                                      
REMARK 465     THR M   276                                                      
REMARK 465     PHE M   277                                                      
REMARK 465     PRO M   278                                                      
REMARK 465     GLU M   279                                                      
REMARK 465     ALA M   280                                                      
REMARK 465     SER M   281                                                      
REMARK 465     VAL M   282                                                      
REMARK 465     ASP M   283                                                      
REMARK 465     ASN M   284                                                      
REMARK 465     VAL M   285                                                      
REMARK 465     LYS M   286                                                      
REMARK 465     LYS M   287                                                      
REMARK 465     ARG M   288                                                      
REMARK 465     LEU M   289                                                      
REMARK 465     LEU M   290                                                      
REMARK 465     PRO M   291                                                      
REMARK 465     LEU M   292                                                      
REMARK 465     ASP M   293                                                      
REMARK 465     ASN M   294                                                      
REMARK 465     GLY M   295                                                      
REMARK 465     MET M   296                                                      
REMARK 465     GLU M   297                                                      
REMARK 465     SER M   298                                                      
REMARK 465     ASP M   299                                                      
REMARK 465     ASP M   300                                                      
REMARK 465     PHE M   301                                                      
REMARK 465     ILE M   302                                                      
REMARK 465     GLU M   303                                                      
REMARK 465     LYS M   304                                                      
REMARK 465     LEU M   305                                                      
REMARK 465     LYS M   306                                                      
REMARK 465     LYS M   307                                                      
REMARK 465     VAL M   308                                                      
REMARK 465     LYS M   309                                                      
REMARK 465     LYS M   310                                                      
REMARK 465     ASN M   311                                                      
REMARK 465     ILE M   312                                                      
REMARK 465     SER M   313                                                      
REMARK 465     ARG M   314                                                      
REMARK 465     GLU M   315                                                      
REMARK 465     ASN M   316                                                      
REMARK 465     ILE M   317                                                      
REMARK 465     SER M   318                                                      
REMARK 465     SER M   319                                                      
REMARK 465     LYS M   320                                                      
REMARK 465     PRO M   321                                                      
REMARK 465     SER M   322                                                      
REMARK 465     VAL M   323                                                      
REMARK 465     GLY M   324                                                      
REMARK 465     LYS M   325                                                      
REMARK 465     LEU M   326                                                      
REMARK 465     GLY M   327                                                      
REMARK 465     GLY M   328                                                      
REMARK 465     PRO M   329                                                      
REMARK 465     LEU M   330                                                      
REMARK 465     LEU M   331                                                      
REMARK 465     ASP M   332                                                      
REMARK 465     TYR M   333                                                      
REMARK 465     LEU M   334                                                      
REMARK 465     SER M   335                                                      
REMARK 465     SER M   336                                                      
REMARK 465     ASP M   337                                                      
REMARK 465     GLU M   338                                                      
REMARK 465     ASP M   339                                                      
REMARK 465     MET N     1                                                      
REMARK 465     ASN N     2                                                      
REMARK 465     ASP N     3                                                      
REMARK 465     ARG N   145                                                      
REMARK 465     ALA N   146                                                      
REMARK 465     THR N   147                                                      
REMARK 465     SER N   148                                                      
REMARK 465     ASP N   149                                                      
REMARK 465     GLY N   150                                                      
REMARK 465     PRO N   151                                                      
REMARK 465     SER N   152                                                      
REMARK 465     THR N   153                                                      
REMARK 465     PRO N   154                                                      
REMARK 465     LEU N   155                                                      
REMARK 465     ILE N   156                                                      
REMARK 465     LYS N   157                                                      
REMARK 465     ASN N   158                                                      
REMARK 465     THR N   159                                                      
REMARK 465     THR N   160                                                      
REMARK 465     ALA N   161                                                      
REMARK 465     LEU N   162                                                      
REMARK 465     TYR N   163                                                      
REMARK 465     LYS N   164                                                      
REMARK 465     ASN N   165                                                      
REMARK 465     GLU N   166                                                      
REMARK 465     LYS N   167                                                      
REMARK 465     GLY N   168                                                      
REMARK 465     ALA N   169                                                      
REMARK 465     ASN N   170                                                      
REMARK 465     GLU N   171                                                      
REMARK 465     VAL N   172                                                      
REMARK 465     LYS N   173                                                      
REMARK 465     ASN N   174                                                      
REMARK 465     LEU N   175                                                      
REMARK 465     GLU N   176                                                      
REMARK 465     LYS N   177                                                      
REMARK 465     TYR N   178                                                      
REMARK 465     ALA N   179                                                      
REMARK 465     SER N   180                                                      
REMARK 465     VAL N   181                                                      
REMARK 465     ASP N   182                                                      
REMARK 465     ILE N   183                                                      
REMARK 465     SER N   184                                                      
REMARK 465     HIS N   185                                                      
REMARK 465     ILE N   186                                                      
REMARK 465     LEU N   187                                                      
REMARK 465     LYS N   188                                                      
REMARK 465     LYS N   189                                                      
REMARK 465     LEU N   190                                                      
REMARK 465     PRO N   191                                                      
REMARK 465     LEU N   192                                                      
REMARK 465     ASN N   193                                                      
REMARK 465     GLU N   194                                                      
REMARK 465     SER N   195                                                      
REMARK 465     PHE N   196                                                      
REMARK 465     LEU N   197                                                      
REMARK 465     GLY N   228                                                      
REMARK 465     ILE N   229                                                      
REMARK 465     LYS N   230                                                      
REMARK 465     LYS N   231                                                      
REMARK 465     TRP N   232                                                      
REMARK 465     LYS N   233                                                      
REMARK 465     ASP N   234                                                      
REMARK 465     GLY N   235                                                      
REMARK 465     ASN N   236                                                      
REMARK 465     SER N   237                                                      
REMARK 465     SER N   267                                                      
REMARK 465     GLU N   268                                                      
REMARK 465     THR N   269                                                      
REMARK 465     LEU N   270                                                      
REMARK 465     VAL N   271                                                      
REMARK 465     THR N   272                                                      
REMARK 465     PRO N   273                                                      
REMARK 465     LYS N   274                                                      
REMARK 465     GLY N   275                                                      
REMARK 465     LEU N   276                                                      
REMARK 465     LYS N   277                                                      
REMARK 465     ARG N   278                                                      
REMARK 465     GLY N   279                                                      
REMARK 465     VAL N   280                                                      
REMARK 465     LEU N   281                                                      
REMARK 465     LEU N   282                                                      
REMARK 465     ILE N   283                                                      
REMARK 465     ASP N   284                                                      
REMARK 465     ARG N   285                                                      
REMARK 465     PHE N   286                                                      
REMARK 465     ARG N   287                                                      
REMARK 465     GLY N   296                                                      
REMARK 465     PHE N   297                                                      
REMARK 465     SER N   298                                                      
REMARK 465     ALA N   299                                                      
REMARK 465     ALA N   300                                                      
REMARK 465     SER N   301                                                      
REMARK 465     PHE N   302                                                      
REMARK 465     GLY N   303                                                      
REMARK 465     THR N   304                                                      
REMARK 465     ASN N   305                                                      
REMARK 465     GLY N   325                                                      
REMARK 465     LEU N   326                                                      
REMARK 465     SER N   327                                                      
REMARK 465     PHE N   328                                                      
REMARK 465     PRO N   329                                                      
REMARK 465     THR N   330                                                      
REMARK 465     LYS N   331                                                      
REMARK 465     SER N   332                                                      
REMARK 465     THR N   333                                                      
REMARK 465     ASP N   334                                                      
REMARK 465     ASN N   335                                                      
REMARK 465     ALA N   336                                                      
REMARK 465     LYS N   337                                                      
REMARK 465     ASN N   338                                                      
REMARK 465     ASP N   339                                                      
REMARK 465     LYS N   340                                                      
REMARK 465     LYS N   341                                                      
REMARK 465     LYS N   342                                                      
REMARK 465     THR N   343                                                      
REMARK 465     SER N   344                                                      
REMARK 465     LYS N   345                                                      
REMARK 465     LYS N   346                                                      
REMARK 465     VAL N   347                                                      
REMARK 465     HIS N   348                                                      
REMARK 465     LYS N   349                                                      
REMARK 465     ASP N   350                                                      
REMARK 465     ARG N   351                                                      
REMARK 465     SER N   352                                                      
REMARK 465     LYS N   353                                                      
REMARK 465     LYS N   354                                                      
REMARK 465     SER N   355                                                      
REMARK 465     LYS N   356                                                      
REMARK 465     PRO N   357                                                      
REMARK 465     ARG N   358                                                      
REMARK 465     ALA N   359                                                      
REMARK 465     ASN N   360                                                      
REMARK 465     LYS N   361                                                      
REMARK 465     LEU N   362                                                      
REMARK 465     THR N   363                                                      
REMARK 465     ILE N   364                                                      
REMARK 465     MET O     1                                                      
REMARK 465     PRO O     2                                                      
REMARK 465     PRO O     3                                                      
REMARK 465     VAL O     4                                                      
REMARK 465     SER O   108                                                      
REMARK 465     GLU O   109                                                      
REMARK 465     ASP O   110                                                      
REMARK 465     SER O   111                                                      
REMARK 465     GLY O   112                                                      
REMARK 465     GLY O   113                                                      
REMARK 465     ALA O   114                                                      
REMARK 465     ALA O   115                                                      
REMARK 465     LEU O   116                                                      
REMARK 465     SER O   117                                                      
REMARK 465     THR O   118                                                      
REMARK 465     GLY O   119                                                      
REMARK 465     VAL O   120                                                      
REMARK 465     THR O   121                                                      
REMARK 465     ASP O   122                                                      
REMARK 465     LEU O   123                                                      
REMARK 465     LYS O   124                                                      
REMARK 465     ALA O   125                                                      
REMARK 465     GLY O   126                                                      
REMARK 465     ASP O   127                                                      
REMARK 465     ILE O   128                                                      
REMARK 465     ASN O   129                                                      
REMARK 465     PRO O   130                                                      
REMARK 465     ASN O   131                                                      
REMARK 465     ALA O   132                                                      
REMARK 465     GLU O   133                                                      
REMARK 465     THR O   134                                                      
REMARK 465     GLN O   135                                                      
REMARK 465     MET O   136                                                      
REMARK 465     ALA O   137                                                      
REMARK 465     ARG O   138                                                      
REMARK 465     PRO O   139                                                      
REMARK 465     ASP O   140                                                      
REMARK 465     ASN O   141                                                      
REMARK 465     GLY O   142                                                      
REMARK 465     ASP O   143                                                      
REMARK 465     GLY O   252                                                      
REMARK 465     LEU O   253                                                      
REMARK 465     ASP O   254                                                      
REMARK 465     GLY O   255                                                      
REMARK 465     ASN O   256                                                      
REMARK 465     LYS O   257                                                      
REMARK 465     ASP O   258                                                      
REMARK 465     LYS O   259                                                      
REMARK 465     PRO O   260                                                      
REMARK 465     SER O   261                                                      
REMARK 465     LYS O   262                                                      
REMARK 465     LYS O   263                                                      
REMARK 465     ASN O   264                                                      
REMARK 465     LYS O   265                                                      
REMARK 465     ASP O   266                                                      
REMARK 465     LYS O   267                                                      
REMARK 465     LYS O   268                                                      
REMARK 465     ARG O   269                                                      
REMARK 465     LYS O   270                                                      
REMARK 465     HIS O   271                                                      
REMARK 465     ASP O   272                                                      
REMARK 465     GLU O   273                                                      
REMARK 465     ASN O   274                                                      
REMARK 465     GLU O   275                                                      
REMARK 465     HIS O   276                                                      
REMARK 465     VAL O   277                                                      
REMARK 465     GLU O   278                                                      
REMARK 465     LYS O   279                                                      
REMARK 465     ALA O   280                                                      
REMARK 465     ALA O   281                                                      
REMARK 465     LEU O   282                                                      
REMARK 465     GLY O   283                                                      
REMARK 465     GLU O   284                                                      
REMARK 465     SER O   285                                                      
REMARK 465     THR O   286                                                      
REMARK 465     THR O   287                                                      
REMARK 465     LEU O   288                                                      
REMARK 465     THR O   289                                                      
REMARK 465     ASP O   290                                                      
REMARK 465     GLU O   291                                                      
REMARK 465     TYR O   292                                                      
REMARK 465     LYS O   293                                                      
REMARK 465     LYS O   294                                                      
REMARK 465     PRO O   295                                                      
REMARK 465     LYS O   296                                                      
REMARK 465     LEU O   297                                                      
REMARK 465     ILE O   298                                                      
REMARK 465     LEU O   299                                                      
REMARK 465     SER O   300                                                      
REMARK 465     ALA O   301                                                      
REMARK 465     PRO O   302                                                      
REMARK 465     GLY O   303                                                      
REMARK 465     THR O   304                                                      
REMARK 465     LYS O   305                                                      
REMARK 465     GLN O   306                                                      
REMARK 465     GLY O   307                                                      
REMARK 465     LYS O   308                                                      
REMARK 465     VAL O   309                                                      
REMARK 465     THR O   310                                                      
REMARK 465     TYR O   311                                                      
REMARK 465     LYS O   312                                                      
REMARK 465     LYS O   313                                                      
REMARK 465     LYS O   314                                                      
REMARK 465     LEU O   315                                                      
REMARK 465     GLU O   316                                                      
REMARK 465     SER O   317                                                      
REMARK 465     LYS O   318                                                      
REMARK 465     ARG O   319                                                      
REMARK 465     GLN O   320                                                      
REMARK 465     LYS O   321                                                      
REMARK 465     LEU O   322                                                      
REMARK 465     ILE O   323                                                      
REMARK 465     GLU O   324                                                      
REMARK 465     ALA O   325                                                      
REMARK 465     GLN O   326                                                      
REMARK 465     ALA O   327                                                      
REMARK 465     THR O   328                                                      
REMARK 465     GLY O   329                                                      
REMARK 465     THR O   330                                                      
REMARK 465     VAL O   331                                                      
REMARK 465     LEU O   332                                                      
REMARK 465     THR O   333                                                      
REMARK 465     PRO O   334                                                      
REMARK 465     LYS O   335                                                      
REMARK 465     GLU O   336                                                      
REMARK 465     LEU O   337                                                      
REMARK 465     LEU O   338                                                      
REMARK 465     PRO O   339                                                      
REMARK 465     HIS O   340                                                      
REMARK 465     ASP O   341                                                      
REMARK 465     SER O   342                                                      
REMARK 465     GLY O   343                                                      
REMARK 465     GLN O   344                                                      
REMARK 465     GLU O   345                                                      
REMARK 465     ASP O   346                                                      
REMARK 465     ASN O   347                                                      
REMARK 465     GLU O   348                                                      
REMARK 465     ARG O   349                                                      
REMARK 465     SER O   350                                                      
REMARK 465     ASN O   351                                                      
REMARK 465     ILE O   352                                                      
REMARK 465     LYS O   353                                                      
REMARK 465     SER O   354                                                      
REMARK 465     GLY O   355                                                      
REMARK 465     LYS O   356                                                      
REMARK 465     GLN O   357                                                      
REMARK 465     LEU O   358                                                      
REMARK 465     LYS O   359                                                      
REMARK 465     SER O   360                                                      
REMARK 465     ARG O   361                                                      
REMARK 465     ILE O   362                                                      
REMARK 465     ARG O   363                                                      
REMARK 465     LYS O   364                                                      
REMARK 465     PHE O   365                                                      
REMARK 465     LEU O   366                                                      
REMARK 465     VAL O   367                                                      
REMARK 465     GLN O   368                                                      
REMARK 465     MET O   369                                                      
REMARK 465     PHE O   370                                                      
REMARK 465     ALA O   371                                                      
REMARK 465     SER O   372                                                      
REMARK 465     LEU O   373                                                      
REMARK 465     PRO O   374                                                      
REMARK 465     SER O   375                                                      
REMARK 465     PRO O   376                                                      
REMARK 465     LYS O   377                                                      
REMARK 465     ASN O   378                                                      
REMARK 465     ASP O   379                                                      
REMARK 465     PHE O   380                                                      
REMARK 465     GLU O   381                                                      
REMARK 465     ILE O   382                                                      
REMARK 465     VAL O   383                                                      
REMARK 465     LEU O   384                                                      
REMARK 465     SER O   385                                                      
REMARK 465     GLU O   386                                                      
REMARK 465     ASP O   387                                                      
REMARK 465     GLU O   388                                                      
REMARK 465     LYS O   389                                                      
REMARK 465     GLU O   390                                                      
REMARK 465     GLU O   391                                                      
REMARK 465     ASP O   392                                                      
REMARK 465     ALA O   393                                                      
REMARK 465     GLU O   394                                                      
REMARK 465     ILE O   395                                                      
REMARK 465     ALA O   396                                                      
REMARK 465     GLU O   397                                                      
REMARK 465     TYR O   398                                                      
REMARK 465     GLU O   399                                                      
REMARK 465     LYS O   400                                                      
REMARK 465     GLU O   401                                                      
REMARK 465     PHE O   402                                                      
REMARK 465     GLU O   403                                                      
REMARK 465     ASN O   404                                                      
REMARK 465     GLU O   405                                                      
REMARK 465     ARG O   406                                                      
REMARK 465     ALA O   407                                                      
REMARK 465     MET O   408                                                      
REMARK 465     ASN O   409                                                      
REMARK 465     GLU O   410                                                      
REMARK 465     GLU O   411                                                      
REMARK 465     ASP O   412                                                      
REMARK 465     ASN O   413                                                      
REMARK 465     PHE O   414                                                      
REMARK 465     ILE O   415                                                      
REMARK 465     GLU O   416                                                      
REMARK 465     PRO O   417                                                      
REMARK 465     PRO O   418                                                      
REMARK 465     SER O   419                                                      
REMARK 465     GLN O   420                                                      
REMARK 465     ASN O   421                                                      
REMARK 465     ASP O   422                                                      
REMARK 465     ALA O   423                                                      
REMARK 465     PRO O   424                                                      
REMARK 465     ARG O   425                                                      
REMARK 465     VAL O   426                                                      
REMARK 465     SER O   427                                                      
REMARK 465     LEU O   428                                                      
REMARK 465     VAL O   429                                                      
REMARK 465     ALA O   430                                                      
REMARK 465     VAL O   431                                                      
REMARK 465     PRO O   432                                                      
REMARK 465     LEU O   433                                                      
REMARK 465     ALA O   434                                                      
REMARK 465     TYR O   435                                                      
REMARK 465     SER O   436                                                      
REMARK 465     THR O   437                                                      
REMARK 465     LEU O   438                                                      
REMARK 465     PRO O   439                                                      
REMARK 465     ILE O   440                                                      
REMARK 465     PRO O   441                                                      
REMARK 465     GLU O   442                                                      
REMARK 465     PHE O   443                                                      
REMARK 465     LYS O   444                                                      
REMARK 465     ASN O   445                                                      
REMARK 465     ASN O   446                                                      
REMARK 465     PRO O   447                                                      
REMARK 465     GLN O   448                                                      
REMARK 465     SER O   449                                                      
REMARK 465     ALA O   450                                                      
REMARK 465     ILE O   451                                                      
REMARK 465     ASP O   452                                                      
REMARK 465     ASN O   453                                                      
REMARK 465     LYS O   454                                                      
REMARK 465     TYR O   455                                                      
REMARK 465     ASN O   456                                                      
REMARK 465     LEU O   457                                                      
REMARK 465     LEU O   458                                                      
REMARK 465     VAL O   459                                                      
REMARK 465     ALA O   460                                                      
REMARK 465     ASN O   461                                                      
REMARK 465     ALA O   462                                                      
REMARK 465     ILE O   463                                                      
REMARK 465     ASN O   464                                                      
REMARK 465     LYS O   465                                                      
REMARK 465     GLU O   466                                                      
REMARK 465     PRO O   467                                                      
REMARK 465     HIS O   468                                                      
REMARK 465     MET O   469                                                      
REMARK 465     VAL O   470                                                      
REMARK 465     PRO O   471                                                      
REMARK 465     GLU O   472                                                      
REMARK 465     ASP O   473                                                      
REMARK 465     THR O   474                                                      
REMARK 465     VAL O   475                                                      
REMARK 465     ASP O   476                                                      
REMARK 465     PHE O   477                                                      
REMARK 465     LEU O   478                                                      
REMARK 465     LYS O   479                                                      
REMARK 465     GLU O   480                                                      
REMARK 465     VAL O   481                                                      
REMARK 465     GLU O   482                                                      
REMARK 465     SER O   483                                                      
REMARK 465     ARG O   484                                                      
REMARK 465     MET O   485                                                      
REMARK 465     GLN O   486                                                      
REMARK 465     HIS O   487                                                      
REMARK 465     ILE O   488                                                      
REMARK 465     THR O   489                                                      
REMARK 465     GLN O   490                                                      
REMARK 465     GLY O   491                                                      
REMARK 465     ARG O   492                                                      
REMARK 465     THR O   493                                                      
REMARK 465     SER O   494                                                      
REMARK 465     MET O   495                                                      
REMARK 465     LYS O   496                                                      
REMARK 465     ILE O   497                                                      
REMARK 465     GLN O   498                                                      
REMARK 465     PHE O   499                                                      
REMARK 465     LYS O   500                                                      
REMARK 465     THR O   501                                                      
REMARK 465     ALA O   502                                                      
REMARK 465     MET O   503                                                      
REMARK 465     PRO O   504                                                      
REMARK 465     PRO O   505                                                      
REMARK 465     THR O   506                                                      
REMARK 465     GLU O   507                                                      
REMARK 465     VAL O   508                                                      
REMARK 465     LEU O   509                                                      
REMARK 465     LEU O   510                                                      
REMARK 465     GLU O   511                                                      
REMARK 465     SER O   512                                                      
REMARK 465     ILE O   513                                                      
REMARK 465     GLN O   514                                                      
REMARK 465     SER O   515                                                      
REMARK 465     LYS O   516                                                      
REMARK 465     VAL O   517                                                      
REMARK 465     GLU O   518                                                      
REMARK 465     SER O   519                                                      
REMARK 465     ILE O   520                                                      
REMARK 465     GLU O   521                                                      
REMARK 465     GLN O   522                                                      
REMARK 465     LEU O   523                                                      
REMARK 465     GLN O   524                                                      
REMARK 465     ARG O   525                                                      
REMARK 465     LYS O   526                                                      
REMARK 465     LEU O   527                                                      
REMARK 465     GLN O   528                                                      
REMARK 465     HIS O   529                                                      
REMARK 465     VAL O   530                                                      
REMARK 465     GLN O   531                                                      
REMARK 465     PRO O   532                                                      
REMARK 465     LEU O   533                                                      
REMARK 465     GLU O   534                                                      
REMARK 465     GLN O   535                                                      
REMARK 465     GLN O   536                                                      
REMARK 465     ASN O   537                                                      
REMARK 465     ASN O   538                                                      
REMARK 465     GLU O   539                                                      
REMARK 465     MET O   540                                                      
REMARK 465     CYS O   541                                                      
REMARK 465     SER O   542                                                      
REMARK 465     THR O   543                                                      
REMARK 465     LEU O   544                                                      
REMARK 465     CYS O   545                                                      
REMARK 465     HIS O   546                                                      
REMARK 465     HIS O   547                                                      
REMARK 465     SER O   548                                                      
REMARK 465     LEU O   549                                                      
REMARK 465     PRO O   550                                                      
REMARK 465     ALA O   551                                                      
REMARK 465     LEU O   552                                                      
REMARK 465     ILE O   553                                                      
REMARK 465     GLU O   554                                                      
REMARK 465     GLY O   555                                                      
REMARK 465     GLN O   556                                                      
REMARK 465     ARG O   557                                                      
REMARK 465     LYS O   558                                                      
REMARK 465     TYR O   559                                                      
REMARK 465     TYR O   560                                                      
REMARK 465     ALA O   561                                                      
REMARK 465     ASP O   562                                                      
REMARK 465     TYR O   563                                                      
REMARK 465     TYR O   564                                                      
REMARK 465     ALA O   565                                                      
REMARK 465     TYR O   566                                                      
REMARK 465     ARG O   567                                                      
REMARK 465     GLN O   568                                                      
REMARK 465     GLU O   569                                                      
REMARK 465     ILE O   570                                                      
REMARK 465     ARG O   571                                                      
REMARK 465     SER O   572                                                      
REMARK 465     LEU O   573                                                      
REMARK 465     GLU O   574                                                      
REMARK 465     GLY O   575                                                      
REMARK 465     ARG O   576                                                      
REMARK 465     ARG O   577                                                      
REMARK 465     LYS O   578                                                      
REMARK 465     ARG O   579                                                      
REMARK 465     LEU O   580                                                      
REMARK 465     GLN O   581                                                      
REMARK 465     ALA O   582                                                      
REMARK 465     MET O   583                                                      
REMARK 465     LEU O   584                                                      
REMARK 465     ASN O   585                                                      
REMARK 465     SER O   586                                                      
REMARK 465     SER O   587                                                      
REMARK 465     SER O   588                                                      
REMARK 465     SER O   589                                                      
REMARK 465     ILE O   590                                                      
REMARK 465     MET P     1                                                      
REMARK 465     THR P     2                                                      
REMARK 465     THR P     3                                                      
REMARK 465     LYS P    43                                                      
REMARK 465     GLU P    44                                                      
REMARK 465     GLU P    45                                                      
REMARK 465     GLU P    46                                                      
REMARK 465     ASN P    47                                                      
REMARK 465     LEU P    48                                                      
REMARK 465     ARG P    49                                                      
REMARK 465     ALA P    50                                                      
REMARK 465     ASN P    51                                                      
REMARK 465     CYS P    52                                                      
REMARK 465     ALA P    53                                                      
REMARK 465     GLN P    54                                                      
REMARK 465     GLU P    55                                                      
REMARK 465     ASP P    56                                                      
REMARK 465     ARG P    57                                                      
REMARK 465     SER P    58                                                      
REMARK 465     ASN P    59                                                      
REMARK 465     ASP P    60                                                      
REMARK 465     LYS P    61                                                      
REMARK 465     SER P    62                                                      
REMARK 465     LEU P    63                                                      
REMARK 465     GLU P    64                                                      
REMARK 465     GLU P    65                                                      
REMARK 465     ALA P    66                                                      
REMARK 465     VAL P    67                                                      
REMARK 465     MET P    68                                                      
REMARK 465     ASN P    69                                                      
REMARK 465     GLU P    70                                                      
REMARK 465     GLU P    71                                                      
REMARK 465     LYS P    72                                                      
REMARK 465     GLN P    73                                                      
REMARK 465     ASP P    74                                                      
REMARK 465     VAL P    75                                                      
REMARK 465     VAL P    76                                                      
REMARK 465     GLY P    77                                                      
REMARK 465     SER P    78                                                      
REMARK 465     GLY P    79                                                      
REMARK 465     ASN P    80                                                      
REMARK 465     LEU P    81                                                      
REMARK 465     GLN P    82                                                      
REMARK 465     GLU P    83                                                      
REMARK 465     THR P    84                                                      
REMARK 465     ARG P    85                                                      
REMARK 465     SER P    86                                                      
REMARK 465     GLU P    87                                                      
REMARK 465     LYS P    88                                                      
REMARK 465     ASP P    89                                                      
REMARK 465     GLN P    90                                                      
REMARK 465     LYS P    91                                                      
REMARK 465     ASP P    92                                                      
REMARK 465     SER P    93                                                      
REMARK 465     LEU P    94                                                      
REMARK 465     GLN P    95                                                      
REMARK 465     GLU P    96                                                      
REMARK 465     LEU P    97                                                      
REMARK 465     LEU P    98                                                      
REMARK 465     VAL P    99                                                      
REMARK 465     THR P   100                                                      
REMARK 465     GLN P   101                                                      
REMARK 465     LYS P   102                                                      
REMARK 465     ASN P   103                                                      
REMARK 465     LYS P   104                                                      
REMARK 465     VAL P   105                                                      
REMARK 465     GLU P   106                                                      
REMARK 465     ASP P   107                                                      
REMARK 465     LYS P   108                                                      
REMARK 465     ALA P   109                                                      
REMARK 465     GLU P   110                                                      
REMARK 465     LEU P   111                                                      
REMARK 465     GLU P   112                                                      
REMARK 465     GLY P   113                                                      
REMARK 465     ASN P   114                                                      
REMARK 465     GLU P   115                                                      
REMARK 465     GLN P   116                                                      
REMARK 465     LEU P   117                                                      
REMARK 465     LYS P   118                                                      
REMARK 465     GLY P   119                                                      
REMARK 465     GLY P   120                                                      
REMARK 465     ASN P   121                                                      
REMARK 465     SER P   122                                                      
REMARK 465     SER P   123                                                      
REMARK 465     ARG P   124                                                      
REMARK 465     ARG P   125                                                      
REMARK 465     HIS P   136                                                      
REMARK 465     LYS P   137                                                      
REMARK 465     VAL P   138                                                      
REMARK 465     THR P   139                                                      
REMARK 465     LYS P   140                                                      
REMARK 465     GLU P   141                                                      
REMARK 465     THR P   142                                                      
REMARK 465     ASN P   143                                                      
REMARK 465     ILE P   144                                                      
REMARK 465     LYS P   145                                                      
REMARK 465     GLU P   146                                                      
REMARK 465     HIS P   147                                                      
REMARK 465     ALA P   148                                                      
REMARK 465     THR P   149                                                      
REMARK 465     LYS P   150                                                      
REMARK 465     LYS P   151                                                      
REMARK 465     SER P   152                                                      
REMARK 465     ALA P   153                                                      
REMARK 465     SER P   154                                                      
REMARK 465     GLY P   155                                                      
REMARK 465     MET R     1                                                      
REMARK 465     HIS R    51                                                      
REMARK 465     ASP R    52                                                      
REMARK 465     LYS R    53                                                      
REMARK 465     ALA R    54                                                      
REMARK 465     SER R    55                                                      
REMARK 465     ARG R    56                                                      
REMARK 465     PRO R    57                                                      
REMARK 465     SER R   117                                                      
REMARK 465     SER R   118                                                      
REMARK 465     LEU R   119                                                      
REMARK 465     TYR R   120                                                      
REMARK 465     THR R   121                                                      
REMARK 465     PRO R   122                                                      
REMARK 465     ARG R   123                                                      
REMARK 465     LYS R   124                                                      
REMARK 465     ALA R   125                                                      
REMARK 465     ARG R   126                                                      
REMARK 465     LEU R   127                                                      
REMARK 465     THR R   128                                                      
REMARK 465     GLU R   129                                                      
REMARK 465     GLU R   130                                                      
REMARK 465     GLN R   131                                                      
REMARK 465     HIS R   132                                                      
REMARK 465     ARG R   133                                                      
REMARK 465     HIS R   134                                                      
REMARK 465     GLU R   135                                                      
REMARK 465     MET S     1                                                      
REMARK 465     ASP S     2                                                      
REMARK 465     THR S     3                                                      
REMARK 465     LEU S     4                                                      
REMARK 465     GLU S     5                                                      
REMARK 465     PRO S     6                                                      
REMARK 465     THR S     7                                                      
REMARK 465     ALA S     8                                                      
REMARK 465     VAL S     9                                                      
REMARK 465     ASP S    10                                                      
REMARK 465     THR S    11                                                      
REMARK 465     HIS S    12                                                      
REMARK 465     VAL S    13                                                      
REMARK 465     SER S    14                                                      
REMARK 465     ALA S    15                                                      
REMARK 465     GLU S    16                                                      
REMARK 465     GLN S    17                                                      
REMARK 465     ILE S    18                                                      
REMARK 465     LEU S    19                                                      
REMARK 465     ARG S    20                                                      
REMARK 465     ASP S    21                                                      
REMARK 465     VAL S    22                                                      
REMARK 465     TYR S    23                                                      
REMARK 465     LYS S    24                                                      
REMARK 465     LYS S    25                                                      
REMARK 465     GLY S    26                                                      
REMARK 465     GLN S    27                                                      
REMARK 465     LYS S    28                                                      
REMARK 465     ALA S    29                                                      
REMARK 465     ARG S    30                                                      
REMARK 465     GLY S    31                                                      
REMARK 465     SER S    32                                                      
REMARK 465     THR S    33                                                      
REMARK 465     ASN S    34                                                      
REMARK 465     ILE S    35                                                      
REMARK 465     GLY S   292                                                      
REMARK 465     ASP S   293                                                      
REMARK 465     ILE S   294                                                      
REMARK 465     ASN S   316                                                      
REMARK 465     ALA S   317                                                      
REMARK 465     TYR S   318                                                      
REMARK 465     ASP S   319                                                      
REMARK 465     SER S   333                                                      
REMARK 465     ARG S   350                                                      
REMARK 465     PRO S   351                                                      
REMARK 465     LYS S   352                                                      
REMARK 465     GLU S   353                                                      
REMARK 465     LEU S   354                                                      
REMARK 465     SER S   355                                                      
REMARK 465     LEU S   378                                                      
REMARK 465     GLU S   379                                                      
REMARK 465     ASN S   380                                                      
REMARK 465     ILE S   396                                                      
REMARK 465     PRO S   397                                                      
REMARK 465     HIS S   398                                                      
REMARK 465     LYS S   399                                                      
REMARK 465     HIS S   400                                                      
REMARK 465     PHE S   401                                                      
REMARK 465     THR S   402                                                      
REMARK 465     HIS S   417                                                      
REMARK 465     ASP S   418                                                      
REMARK 465     LEU S   433                                                      
REMARK 465     CYS S   434                                                      
REMARK 465     PRO S   435                                                      
REMARK 465     LYS S   436                                                      
REMARK 465     ALA S   437                                                      
REMARK 465     LYS S   438                                                      
REMARK 465     LYS S   451                                                      
REMARK 465     PRO S   468                                                      
REMARK 465     SER S   469                                                      
REMARK 465     LEU S   484                                                      
REMARK 465     ASN S   501                                                      
REMARK 465     SER S   502                                                      
REMARK 465     ASP S   503                                                      
REMARK 465     PHE S   504                                                      
REMARK 465     LEU S   505                                                      
REMARK 465     THR S   506                                                      
REMARK 465     THR S   522                                                      
REMARK 465     GLU S   523                                                      
REMARK 465     SER S   524                                                      
REMARK 465     GLN S   525                                                      
REMARK 465     GLU S   526                                                      
REMARK 465     PHE S   527                                                      
REMARK 465     GLU S   528                                                      
REMARK 465     LYS S   529                                                      
REMARK 465     GLN S   542                                                      
REMARK 465     TYR S   543                                                      
REMARK 465     SER S   544                                                      
REMARK 465     SER S   557                                                      
REMARK 465     THR S   558                                                      
REMARK 465     PRO S   559                                                      
REMARK 465     THR S   560                                                      
REMARK 465     GLU S   561                                                      
REMARK 465     GLN S   562                                                      
REMARK 465     GLN S   563                                                      
REMARK 465     LEU S   564                                                      
REMARK 465     LEU S   565                                                      
REMARK 465     ASP S   566                                                      
REMARK 465     LEU S   567                                                      
REMARK 465     ALA S   568                                                      
REMARK 465     LYS S   569                                                      
REMARK 465     LEU S   570                                                      
REMARK 465     GLN S   571                                                      
REMARK 465     SER S   572                                                      
REMARK 465     GLU S   573                                                      
REMARK 465     ASN S   574                                                      
REMARK 465     VAL S   575                                                      
REMARK 465     ASP S   576                                                      
REMARK 465     GLU S   577                                                      
REMARK 465     ASP S   578                                                      
REMARK 465     ILE S   579                                                      
REMARK 465     GLU S   580                                                      
REMARK 465     PHE S   581                                                      
REMARK 465     GLU S   582                                                      
REMARK 465     ILE S   583                                                      
REMARK 465     THR S   584                                                      
REMARK 465     ASP S   585                                                      
REMARK 465     GLU S   586                                                      
REMARK 465     ASN S   587                                                      
REMARK 465     LYS S   588                                                      
REMARK 465     LEU S   589                                                      
REMARK 465     GLU S   590                                                      
REMARK 465     ALA S   591                                                      
REMARK 465     ARG S   592                                                      
REMARK 465     LYS S   593                                                      
REMARK 465     VAL S   594                                                      
REMARK 465     PHE S   595                                                      
REMARK 465     GLU S   596                                                      
REMARK 465     GLU S   597                                                      
REMARK 465     ALA S   598                                                      
REMARK 465     ILE S   599                                                      
REMARK 465     VAL S   600                                                      
REMARK 465     PHE S   601                                                      
REMARK 465     PHE S   602                                                      
REMARK 465     LYS S   603                                                      
REMARK 465     GLU S   604                                                      
REMARK 465     LYS S   605                                                      
REMARK 465     ASP S   606                                                      
REMARK 465     ASP S   607                                                      
REMARK 465     LYS S   608                                                      
REMARK 465     GLN S   609                                                      
REMARK 465     GLY S   610                                                      
REMARK 465     ARG S   611                                                      
REMARK 465     LEU S   612                                                      
REMARK 465     SER S   613                                                      
REMARK 465     ILE S   614                                                      
REMARK 465     LEU S   615                                                      
REMARK 465     GLU S   616                                                      
REMARK 465     ALA S   617                                                      
REMARK 465     LEU S   618                                                      
REMARK 465     LYS S   619                                                      
REMARK 465     ASP S   620                                                      
REMARK 465     TYR S   621                                                      
REMARK 465     GLU S   622                                                      
REMARK 465     GLU S   623                                                      
REMARK 465     THR S   624                                                      
REMARK 465     TYR S   625                                                      
REMARK 465     GLY S   626                                                      
REMARK 465     THR S   627                                                      
REMARK 465     GLU S   628                                                      
REMARK 465     LEU S   629                                                      
REMARK 465     ASP S   630                                                      
REMARK 465     GLN S   631                                                      
REMARK 465     GLU S   632                                                      
REMARK 465     THR S   633                                                      
REMARK 465     VAL S   634                                                      
REMARK 465     LYS S   635                                                      
REMARK 465     LYS S   636                                                      
REMARK 465     ARG S   637                                                      
REMARK 465     PHE S   638                                                      
REMARK 465     PRO S   639                                                      
REMARK 465     LYS S   640                                                      
REMARK 465     VAL S   641                                                      
REMARK 465     ILE S   642                                                      
REMARK 465     LYS S   643                                                      
REMARK 465     LYS S   644                                                      
REMARK 465     VAL S   645                                                      
REMARK 465     ARG S   646                                                      
REMARK 465     LEU S   647                                                      
REMARK 465     GLN S   648                                                      
REMARK 465     ASN S   649                                                      
REMARK 465     GLY S   650                                                      
REMARK 465     VAL S   651                                                      
REMARK 465     GLU S   652                                                      
REMARK 465     GLU S   653                                                      
REMARK 465     GLU S   654                                                      
REMARK 465     PHE S   655                                                      
REMARK 465     VAL S   656                                                      
REMARK 465     ASP S   657                                                      
REMARK 465     TYR S   658                                                      
REMARK 465     ILE S   659                                                      
REMARK 465     PHE S   660                                                      
REMARK 465     PRO S   661                                                      
REMARK 465     ASP S   662                                                      
REMARK 465     ASP S   663                                                      
REMARK 465     ILE S   664                                                      
REMARK 465     ASP S   665                                                      
REMARK 465     ASP S   666                                                      
REMARK 465     ASP S   667                                                      
REMARK 465     LYS S   668                                                      
REMARK 465     PRO S   669                                                      
REMARK 465     LYS S   670                                                      
REMARK 465     PRO S   671                                                      
REMARK 465     SER S   672                                                      
REMARK 465     LYS S   673                                                      
REMARK 465     PHE S   674                                                      
REMARK 465     LEU S   675                                                      
REMARK 465     GLU S   676                                                      
REMARK 465     LEU S   677                                                      
REMARK 465     ALA S   678                                                      
REMARK 465     LYS S   679                                                      
REMARK 465     LYS S   680                                                      
REMARK 465     TRP S   681                                                      
REMARK 465     LYS S   682                                                      
REMARK 465     GLN S   683                                                      
REMARK 465     GLU S   684                                                      
REMARK 465     GLN S   685                                                      
REMARK 465     ALA S   686                                                      
REMARK 465     LEU S   687                                                      
REMARK 465     MET T     1                                                      
REMARK 465     SER T     2                                                      
REMARK 465     ALA T     3                                                      
REMARK 465     TYR T     4                                                      
REMARK 465     ILE T     5                                                      
REMARK 465     ALA T     6                                                      
REMARK 465     MET T     7                                                      
REMARK 465     LYS T     8                                                      
REMARK 465     GLY T     9                                                      
REMARK 465     VAL T    10                                                      
REMARK 465     ILE T    11                                                      
REMARK 465     THR T    12                                                      
REMARK 465     ASN T    13                                                      
REMARK 465     VAL T    14                                                      
REMARK 465     ASP T    15                                                      
REMARK 465     GLU T    16                                                      
REMARK 465     ASN T    17                                                      
REMARK 465     ILE T    18                                                      
REMARK 465     ARG T    19                                                      
REMARK 465     ASN T    20                                                      
REMARK 465     ASP T    21                                                      
REMARK 465     GLU T    22                                                      
REMARK 465     ASP T    23                                                      
REMARK 465     VAL T    24                                                      
REMARK 465     ALA T    25                                                      
REMARK 465     PHE T    26                                                      
REMARK 465     GLU T    27                                                      
REMARK 465     TYR T    28                                                      
REMARK 465     GLU T    29                                                      
REMARK 465     ILE T    30                                                      
REMARK 465     GLN T    31                                                      
REMARK 465     LYS T    32                                                      
REMARK 465     THR T    33                                                      
REMARK 465     PRO T    34                                                      
REMARK 465     GLN T    35                                                      
REMARK 465     ASN T    36                                                      
REMARK 465     ILE T    37                                                      
REMARK 465     LEU T    38                                                      
REMARK 465     THR T    39                                                      
REMARK 465     TRP T    40                                                      
REMARK 465     LYS T    41                                                      
REMARK 465     ARG T    42                                                      
REMARK 465     TYR T    43                                                      
REMARK 465     ILE T    44                                                      
REMARK 465     GLU T    45                                                      
REMARK 465     TYR T    46                                                      
REMARK 465     TRP T    47                                                      
REMARK 465     LYS T    48                                                      
REMARK 465     GLU T    49                                                      
REMARK 465     GLU T    50                                                      
REMARK 465     GLY T    51                                                      
REMARK 465     ARG T    52                                                      
REMARK 465     THR T    53                                                      
REMARK 465     ASP T    54                                                      
REMARK 465     LYS T    55                                                      
REMARK 465     GLN T    56                                                      
REMARK 465     ILE T    57                                                      
REMARK 465     ARG T    58                                                      
REMARK 465     TRP T    59                                                      
REMARK 465     LEU T    60                                                      
REMARK 465     TYR T    61                                                      
REMARK 465     GLU T    62                                                      
REMARK 465     ARG T    63                                                      
REMARK 465     PHE T    64                                                      
REMARK 465     CYS T    65                                                      
REMARK 465     SER T    66                                                      
REMARK 465     GLN T    67                                                      
REMARK 465     PHE T    68                                                      
REMARK 465     VAL T    69                                                      
REMARK 465     THR T    70                                                      
REMARK 465     ASP T    71                                                      
REMARK 465     THR T    72                                                      
REMARK 465     SER T    73                                                      
REMARK 465     ILE T    74                                                      
REMARK 465     TRP T    75                                                      
REMARK 465     GLU T    76                                                      
REMARK 465     ASP T    77                                                      
REMARK 465     TYR T    78                                                      
REMARK 465     ILE T    79                                                      
REMARK 465     ARG T    80                                                      
REMARK 465     TRP T    81                                                      
REMARK 465     GLU T    82                                                      
REMARK 465     SER T    83                                                      
REMARK 465     THR T    84                                                      
REMARK 465     LYS T    85                                                      
REMARK 465     GLU T    86                                                      
REMARK 465     VAL T    87                                                      
REMARK 465     VAL T    88                                                      
REMARK 465     GLU T    89                                                      
REMARK 465     THR T    90                                                      
REMARK 465     SER T    91                                                      
REMARK 465     ARG T    92                                                      
REMARK 465     ILE T    93                                                      
REMARK 465     PHE T    94                                                      
REMARK 465     TRP T    95                                                      
REMARK 465     LEU T    96                                                      
REMARK 465     PHE T    97                                                      
REMARK 465     GLN T    98                                                      
REMARK 465     ARG T    99                                                      
REMARK 465     CYS T   100                                                      
REMARK 465     LEU T   101                                                      
REMARK 465     LYS T   102                                                      
REMARK 465     SER T   103                                                      
REMARK 465     CYS T   104                                                      
REMARK 465     VAL T   105                                                      
REMARK 465     ARG T   106                                                      
REMARK 465     ASP T   107                                                      
REMARK 465     CYS T   108                                                      
REMARK 465     ASP T   109                                                      
REMARK 465     ARG T   110                                                      
REMARK 465     ILE T   111                                                      
REMARK 465     CYS T   112                                                      
REMARK 465     LEU T   113                                                      
REMARK 465     SER T   114                                                      
REMARK 465     TYR T   115                                                      
REMARK 465     LEU T   116                                                      
REMARK 465     GLU T   117                                                      
REMARK 465     LEU T   118                                                      
REMARK 465     ALA T   119                                                      
REMARK 465     ILE T   120                                                      
REMARK 465     GLU T   121                                                      
REMARK 465     GLN T   122                                                      
REMARK 465     TYR T   123                                                      
REMARK 465     ASP T   124                                                      
REMARK 465     LEU T   125                                                      
REMARK 465     ALA T   126                                                      
REMARK 465     MET T   127                                                      
REMARK 465     ILE T   128                                                      
REMARK 465     ARG T   129                                                      
REMARK 465     HIS T   130                                                      
REMARK 465     ALA T   131                                                      
REMARK 465     LEU T   132                                                      
REMARK 465     ALA T   133                                                      
REMARK 465     SER T   134                                                      
REMARK 465     SER T   135                                                      
REMARK 465     LEU T   136                                                      
REMARK 465     MET T   137                                                      
REMARK 465     LYS T   138                                                      
REMARK 465     MET T   139                                                      
REMARK 465     GLU T   140                                                      
REMARK 465     ARG T   141                                                      
REMARK 465     GLU T   142                                                      
REMARK 465     MET T   143                                                      
REMARK 465     HIS T   144                                                      
REMARK 465     ARG T   145                                                      
REMARK 465     LYS T   146                                                      
REMARK 465     VAL T   147                                                      
REMARK 465     TRP T   148                                                      
REMARK 465     ASP T   149                                                      
REMARK 465     PRO T   150                                                      
REMARK 465     VAL T   151                                                      
REMARK 465     ILE T   152                                                      
REMARK 465     LYS T   153                                                      
REMARK 465     PHE T   154                                                      
REMARK 465     VAL T   155                                                      
REMARK 465     GLU T   156                                                      
REMARK 465     GLU T   157                                                      
REMARK 465     LYS T   158                                                      
REMARK 465     VAL T   159                                                      
REMARK 465     LEU T   160                                                      
REMARK 465     PRO T   161                                                      
REMARK 465     LEU T   162                                                      
REMARK 465     THR T   163                                                      
REMARK 465     GLN T   164                                                      
REMARK 465     LEU T   165                                                      
REMARK 465     ASP T   166                                                      
REMARK 465     SER T   167                                                      
REMARK 465     THR T   168                                                      
REMARK 465     GLN T   169                                                      
REMARK 465     GLU T   170                                                      
REMARK 465     ASP T   171                                                      
REMARK 465     GLU T   172                                                      
REMARK 465     GLU T   173                                                      
REMARK 465     GLU T   174                                                      
REMARK 465     SER T   175                                                      
REMARK 465     THR T   176                                                      
REMARK 465     ASP T   177                                                      
REMARK 465     GLU T   178                                                      
REMARK 465     ALA T   179                                                      
REMARK 465     GLU T   180                                                      
REMARK 465     LEU T   181                                                      
REMARK 465     ILE T   182                                                      
REMARK 465     ASN T   183                                                      
REMARK 465     VAL T   184                                                      
REMARK 465     LEU T   185                                                      
REMARK 465     LEU T   186                                                      
REMARK 465     VAL T   187                                                      
REMARK 465     LYS T   188                                                      
REMARK 465     GLY T   189                                                      
REMARK 465     PHE T   190                                                      
REMARK 465     THR T   191                                                      
REMARK 465     LYS T   192                                                      
REMARK 465     GLY T   193                                                      
REMARK 465     GLY T   194                                                      
REMARK 465     PHE T   195                                                      
REMARK 465     ILE T   196                                                      
REMARK 465     SER T   197                                                      
REMARK 465     GLU T   198                                                      
REMARK 465     GLU T   199                                                      
REMARK 465     ILE T   200                                                      
REMARK 465     SER T   201                                                      
REMARK 465     GLU T   202                                                      
REMARK 465     ASN T   203                                                      
REMARK 465     GLY T   204                                                      
REMARK 465     SER T   205                                                      
REMARK 465     ARG T   206                                                      
REMARK 465     GLY T   207                                                      
REMARK 465     ASP T   208                                                      
REMARK 465     ILE T   209                                                      
REMARK 465     TRP T   210                                                      
REMARK 465     SER T   211                                                      
REMARK 465     SER T   212                                                      
REMARK 465     HIS T   213                                                      
REMARK 465     ILE T   214                                                      
REMARK 465     LEU T   215                                                      
REMARK 465     GLU T   216                                                      
REMARK 465     ARG T   217                                                      
REMARK 465     TYR T   218                                                      
REMARK 465     LEU T   219                                                      
REMARK 465     LYS T   220                                                      
REMARK 465     VAL T   221                                                      
REMARK 465     ALA T   222                                                      
REMARK 465     PRO T   223                                                      
REMARK 465     GLN T   224                                                      
REMARK 465     GLN T   225                                                      
REMARK 465     LYS T   226                                                      
REMARK 465     ARG T   227                                                      
REMARK 465     ASN T   228                                                      
REMARK 465     GLU T   229                                                      
REMARK 465     SER T   230                                                      
REMARK 465     LEU T   231                                                      
REMARK 465     ALA T   232                                                      
REMARK 465     THR T   233                                                      
REMARK 465     LEU T   234                                                      
REMARK 465     ALA T   235                                                      
REMARK 465     LEU T   236                                                      
REMARK 465     THR T   237                                                      
REMARK 465     ARG T   238                                                      
REMARK 465     ASP T   239                                                      
REMARK 465     ASN T   240                                                      
REMARK 465     ILE T   241                                                      
REMARK 465     THR T   242                                                      
REMARK 465     ILE T   243                                                      
REMARK 465     LYS T   244                                                      
REMARK 465     SER T   245                                                      
REMARK 465     VAL T   246                                                      
REMARK 465     TYR T   247                                                      
REMARK 465     GLU T   248                                                      
REMARK 465     LYS T   249                                                      
REMARK 465     TYR T   250                                                      
REMARK 465     LEU T   251                                                      
REMARK 465     PRO T   252                                                      
REMARK 465     GLN T   253                                                      
REMARK 465     ASP T   254                                                      
REMARK 465     GLU T   255                                                      
REMARK 465     ASN T   256                                                      
REMARK 465     SER T   257                                                      
REMARK 465     GLY T   258                                                      
REMARK 465     LYS T   259                                                      
REMARK 465     TYR T   260                                                      
REMARK 465     LEU T   261                                                      
REMARK 465     PRO T   262                                                      
REMARK 465     SER T   263                                                      
REMARK 465     SER T   264                                                      
REMARK 465     GLU T   265                                                      
REMARK 465     LEU T   266                                                      
REMARK 465     PRO T   267                                                      
REMARK 465     PHE T   268                                                      
REMARK 465     GLU T   269                                                      
REMARK 465     LEU T   270                                                      
REMARK 465     ASN T   271                                                      
REMARK 465     PHE T   272                                                      
REMARK 465     ASN T   273                                                      
REMARK 465     TYR T   274                                                      
REMARK 465     LEU T   275                                                      
REMARK 465     ALA T   276                                                      
REMARK 465     SER T   277                                                      
REMARK 465     LEU T   278                                                      
REMARK 465     GLU T   279                                                      
REMARK 465     LYS T   280                                                      
REMARK 465     LEU T   281                                                      
REMARK 465     GLY T   282                                                      
REMARK 465     LEU T   283                                                      
REMARK 465     ASP T   284                                                      
REMARK 465     ASN T   285                                                      
REMARK 465     GLN T   286                                                      
REMARK 465     TYR T   287                                                      
REMARK 465     GLU T   288                                                      
REMARK 465     GLU T   289                                                      
REMARK 465     PHE T   290                                                      
REMARK 465     MET T   291                                                      
REMARK 465     ARG T   292                                                      
REMARK 465     GLN T   293                                                      
REMARK 465     MET T   294                                                      
REMARK 465     ASN T   295                                                      
REMARK 465     GLY T   296                                                      
REMARK 465     ILE T   297                                                      
REMARK 465     TYR T   298                                                      
REMARK 465     PRO T   299                                                      
REMARK 465     ASP T   300                                                      
REMARK 465     LYS T   301                                                      
REMARK 465     TRP T   302                                                      
REMARK 465     LEU T   303                                                      
REMARK 465     PHE T   304                                                      
REMARK 465     LEU T   305                                                      
REMARK 465     ILE T   306                                                      
REMARK 465     LEU T   307                                                      
REMARK 465     SER T   308                                                      
REMARK 465     LEU T   309                                                      
REMARK 465     ALA T   310                                                      
REMARK 465     LYS T   311                                                      
REMARK 465     TYR T   312                                                      
REMARK 465     TYR T   313                                                      
REMARK 465     ILE T   314                                                      
REMARK 465     SER T   315                                                      
REMARK 465     ARG T   316                                                      
REMARK 465     GLY T   317                                                      
REMARK 465     ARG T   318                                                      
REMARK 465     LEU T   319                                                      
REMARK 465     ASP T   320                                                      
REMARK 465     SER T   321                                                      
REMARK 465     CYS T   322                                                      
REMARK 465     GLY T   323                                                      
REMARK 465     ASP T   324                                                      
REMARK 465     LEU T   325                                                      
REMARK 465     LEU T   326                                                      
REMARK 465     LYS T   327                                                      
REMARK 465     LYS T   328                                                      
REMARK 465     SER T   329                                                      
REMARK 465     LEU T   330                                                      
REMARK 465     GLN T   331                                                      
REMARK 465     GLN T   332                                                      
REMARK 465     THR T   333                                                      
REMARK 465     LEU T   334                                                      
REMARK 465     ARG T   335                                                      
REMARK 465     TYR T   336                                                      
REMARK 465     SER T   337                                                      
REMARK 465     ASP T   338                                                      
REMARK 465     PHE T   339                                                      
REMARK 465     ASP T   340                                                      
REMARK 465     ARG T   341                                                      
REMARK 465     ILE T   342                                                      
REMARK 465     TYR T   343                                                      
REMARK 465     ASN T   344                                                      
REMARK 465     PHE T   345                                                      
REMARK 465     TYR T   346                                                      
REMARK 465     LEU T   347                                                      
REMARK 465     LEU T   348                                                      
REMARK 465     PHE T   349                                                      
REMARK 465     GLU T   350                                                      
REMARK 465     GLN T   351                                                      
REMARK 465     GLU T   352                                                      
REMARK 465     CYS T   353                                                      
REMARK 465     SER T   354                                                      
REMARK 465     GLN T   355                                                      
REMARK 465     PHE T   356                                                      
REMARK 465     ILE T   357                                                      
REMARK 465     LEU T   358                                                      
REMARK 465     GLY T   359                                                      
REMARK 465     LYS T   360                                                      
REMARK 465     LEU T   361                                                      
REMARK 465     LYS T   362                                                      
REMARK 465     GLU T   363                                                      
REMARK 465     ASN T   364                                                      
REMARK 465     ASP T   365                                                      
REMARK 465     SER T   366                                                      
REMARK 465     LYS T   367                                                      
REMARK 465     PHE T   368                                                      
REMARK 465     PHE T   369                                                      
REMARK 465     ASN T   370                                                      
REMARK 465     GLN T   371                                                      
REMARK 465     LYS T   372                                                      
REMARK 465     ASP T   373                                                      
REMARK 465     TRP T   374                                                      
REMARK 465     THR T   375                                                      
REMARK 465     GLU T   376                                                      
REMARK 465     LYS T   377                                                      
REMARK 465     LEU T   378                                                      
REMARK 465     GLN T   379                                                      
REMARK 465     ALA T   380                                                      
REMARK 465     HIS T   381                                                      
REMARK 465     MET T   382                                                      
REMARK 465     ALA T   383                                                      
REMARK 465     THR T   384                                                      
REMARK 465     PHE T   385                                                      
REMARK 465     GLU T   386                                                      
REMARK 465     SER T   387                                                      
REMARK 465     LEU T   388                                                      
REMARK 465     ILE T   389                                                      
REMARK 465     ASN T   390                                                      
REMARK 465     LEU T   391                                                      
REMARK 465     TYR T   392                                                      
REMARK 465     ASP T   393                                                      
REMARK 465     ILE T   394                                                      
REMARK 465     TYR T   395                                                      
REMARK 465     LEU T   396                                                      
REMARK 465     ASN T   397                                                      
REMARK 465     ASP T   398                                                      
REMARK 465     VAL T   399                                                      
REMARK 465     ALA T   400                                                      
REMARK 465     LEU T   401                                                      
REMARK 465     ARG T   402                                                      
REMARK 465     GLN T   403                                                      
REMARK 465     ASP T   404                                                      
REMARK 465     SER T   405                                                      
REMARK 465     ASN T   406                                                      
REMARK 465     LYS T   498                                                      
REMARK 465     GLU T   499                                                      
REMARK 465     GLY T   500                                                      
REMARK 465     LYS T   524                                                      
REMARK 465     TYR T   525                                                      
REMARK 465     LYS T   526                                                      
REMARK 465     ASN T   527                                                      
REMARK 465     GLY T   528                                                      
REMARK 465     HIS T   529                                                      
REMARK 465     ARG T   530                                                      
REMARK 465     LYS T   531                                                      
REMARK 465     ILE T   532                                                      
REMARK 465     PRO T   533                                                      
REMARK 465     ALA T   534                                                      
REMARK 465     GLN T   535                                                      
REMARK 465     THR T   536                                                      
REMARK 465     VAL T   537                                                      
REMARK 465     LEU T   538                                                      
REMARK 465     PHE T   539                                                      
REMARK 465     ASN T   540                                                      
REMARK 465     CYS T   556                                                      
REMARK 465     PRO T   557                                                      
REMARK 465     LYS T   558                                                      
REMARK 465     ASP T   559                                                      
REMARK 465     ALA T   560                                                      
REMARK 465     ASN T   561                                                      
REMARK 465     SER T   562                                                      
REMARK 465     SER T   563                                                      
REMARK 465     ASP T   564                                                      
REMARK 465     LYS T   565                                                      
REMARK 465     LEU T   582                                                      
REMARK 465     ILE T   583                                                      
REMARK 465     THR T   584                                                      
REMARK 465     TYR T   599                                                      
REMARK 465     GLU T   600                                                      
REMARK 465     GLN T   635                                                      
REMARK 465     LEU T   636                                                      
REMARK 465     SER T   637                                                      
REMARK 465     SER T   638                                                      
REMARK 465     LEU T   639                                                      
REMARK 465     SER T   640                                                      
REMARK 465     GLY T   678                                                      
REMARK 465     LEU T   679                                                      
REMARK 465     GLY T   694                                                      
REMARK 465     THR T   695                                                      
REMARK 465     VAL T   696                                                      
REMARK 465     SER T   697                                                      
REMARK 465     VAL T   698                                                      
REMARK 465     SER T   699                                                      
REMARK 465     THR T   700                                                      
REMARK 465     HIS T   701                                                      
REMARK 465     LEU T   720                                                      
REMARK 465     GLY T   721                                                      
REMARK 465     PRO T   722                                                      
REMARK 465     LEU T   736                                                      
REMARK 465     PRO T   737                                                      
REMARK 465     ASN T   738                                                      
REMARK 465     GLY T   756                                                      
REMARK 465     GLU T   757                                                      
REMARK 465     LEU T   772                                                      
REMARK 465     PRO T   773                                                      
REMARK 465     PRO T   774                                                      
REMARK 465     SER T   775                                                      
REMARK 465     ARG T   776                                                      
REMARK 465     HIS T   791                                                      
REMARK 465     GLY T   792                                                      
REMARK 465     ASP T   793                                                      
REMARK 465     LYS T   794                                                      
REMARK 465     GLU T   795                                                      
REMARK 465     THR T   796                                                      
REMARK 465     TYR T   797                                                      
REMARK 465     LYS T   798                                                      
REMARK 465     ASP T   799                                                      
REMARK 465     MET T   800                                                      
REMARK 465     LEU T   801                                                      
REMARK 465     LYS T   802                                                      
REMARK 465     MET T   803                                                      
REMARK 465     LYS T   804                                                      
REMARK 465     LYS T   805                                                      
REMARK 465     VAL T   806                                                      
REMARK 465     LEU T   807                                                      
REMARK 465     GLU T   808                                                      
REMARK 465     SER T   809                                                      
REMARK 465     ASN T   810                                                      
REMARK 465     MET T   811                                                      
REMARK 465     LEU T   812                                                      
REMARK 465     ILE T   813                                                      
REMARK 465     ASP T   814                                                      
REMARK 465     SER T   815                                                      
REMARK 465     ALA T   816                                                      
REMARK 465     SER T   817                                                      
REMARK 465     VAL T   818                                                      
REMARK 465     SER T   819                                                      
REMARK 465     HIS T   820                                                      
REMARK 465     GLU T   821                                                      
REMARK 465     GLU T   822                                                      
REMARK 465     GLY T   823                                                      
REMARK 465     ASN T   824                                                      
REMARK 465     ILE T   825                                                      
REMARK 465     ASN T   826                                                      
REMARK 465     PHE T   827                                                      
REMARK 465     VAL T   828                                                      
REMARK 465     ALA T   829                                                      
REMARK 465     ALA T   830                                                      
REMARK 465     ALA T   831                                                      
REMARK 465     THR T   832                                                      
REMARK 465     SER T   833                                                      
REMARK 465     HIS T   834                                                      
REMARK 465     ALA T   835                                                      
REMARK 465     PRO T   836                                                      
REMARK 465     ASN T   837                                                      
REMARK 465     SER T   838                                                      
REMARK 465     HIS T   839                                                      
REMARK 465     THR T   840                                                      
REMARK 465     LEU T   841                                                      
REMARK 465     THR T   842                                                      
REMARK 465     GLN T   843                                                      
REMARK 465     SER T   844                                                      
REMARK 465     THR T   845                                                      
REMARK 465     SER T   846                                                      
REMARK 465     SER T   847                                                      
REMARK 465     TYR T   848                                                      
REMARK 465     SER T   849                                                      
REMARK 465     ILE T   850                                                      
REMARK 465     ASN T   851                                                      
REMARK 465     PRO T   852                                                      
REMARK 465     ASP T   853                                                      
REMARK 465     GLU T   854                                                      
REMARK 465     ILE T   855                                                      
REMARK 465     GLU T   856                                                      
REMARK 465     LEU T   857                                                      
REMARK 465     ASP T   858                                                      
REMARK 465     ILE T   859                                                      
REMARK 465     MET a     1                                                      
REMARK 465     ASP a     2                                                      
REMARK 465     LEU a     3                                                      
REMARK 465     ASP a     4                                                      
REMARK 465     LEU a     5                                                      
REMARK 465     ALA a     6                                                      
REMARK 465     SER a     7                                                      
REMARK 465     ILE a     8                                                      
REMARK 465     LEU a     9                                                      
REMARK 465     LYS a    10                                                      
REMARK 465     GLY a    11                                                      
REMARK 465     GLU a    12                                                      
REMARK 465     ILE a    13                                                      
REMARK 465     SER a    14                                                      
REMARK 465     LYS a    15                                                      
REMARK 465     LYS a    16                                                      
REMARK 465     LYS a    17                                                      
REMARK 465     LYS a    18                                                      
REMARK 465     GLU a    19                                                      
REMARK 465     LEU a    20                                                      
REMARK 465     ALA a    21                                                      
REMARK 465     ASN a    22                                                      
REMARK 465     SER a    23                                                      
REMARK 465     LYS a    24                                                      
REMARK 465     GLY a    25                                                      
REMARK 465     VAL a    26                                                      
REMARK 465     GLN a    27                                                      
REMARK 465     PRO a    28                                                      
REMARK 465     PRO a    29                                                      
REMARK 465     CYS a    30                                                      
REMARK 465     THR a    31                                                      
REMARK 465     GLU a    32                                                      
REMARK 465     LYS a    33                                                      
REMARK 465     PHE a    34                                                      
REMARK 465     GLN a    35                                                      
REMARK 465     PRO a    36                                                      
REMARK 465     HIS a    37                                                      
REMARK 465     GLU a    38                                                      
REMARK 465     SER a    39                                                      
REMARK 465     ALA a    40                                                      
REMARK 465     ASN a    41                                                      
REMARK 465     ILE a    42                                                      
REMARK 465     ASP a    43                                                      
REMARK 465     GLU a    44                                                      
REMARK 465     THR a    45                                                      
REMARK 465     PRO a    46                                                      
REMARK 465     ARG a    47                                                      
REMARK 465     GLN a    48                                                      
REMARK 465     VAL a    49                                                      
REMARK 465     GLU a    50                                                      
REMARK 465     GLN a    51                                                      
REMARK 465     GLU a    52                                                      
REMARK 465     SER a    53                                                      
REMARK 465     THR a    54                                                      
REMARK 465     ASP a    55                                                      
REMARK 465     GLU a    56                                                      
REMARK 465     GLU a    57                                                      
REMARK 465     ASN a    58                                                      
REMARK 465     LEU a    59                                                      
REMARK 465     SER a    60                                                      
REMARK 465     ASP a    61                                                      
REMARK 465     ASN a    62                                                      
REMARK 465     GLN a    63                                                      
REMARK 465     SER a    64                                                      
REMARK 465     ASP a    65                                                      
REMARK 465     ASP a    66                                                      
REMARK 465     ILE a    67                                                      
REMARK 465     ARG a    68                                                      
REMARK 465     THR a    69                                                      
REMARK 465     THR a    70                                                      
REMARK 465     ILE a    71                                                      
REMARK 465     SER a    72                                                      
REMARK 465     LYS a    73                                                      
REMARK 465     LEU a    74                                                      
REMARK 465     GLU a    75                                                      
REMARK 465     GLU a   104                                                      
REMARK 465     GLY a   105                                                      
REMARK 465     GLY a   189                                                      
REMARK 465     ASN a   190                                                      
REMARK 465     VAL a   191                                                      
REMARK 465     ALA a   192                                                      
REMARK 465     TRP a   193                                                      
REMARK 465     PRO a   194                                                      
REMARK 465     ILE a   195                                                      
REMARK 465     GLY a   196                                                      
REMARK 465     VAL a   197                                                      
REMARK 465     THR a   198                                                      
REMARK 465     SER a   199                                                      
REMARK 465     VAL a   200                                                      
REMARK 465     GLY a   201                                                      
REMARK 465     ILE a   202                                                      
REMARK 465     HIS a   203                                                      
REMARK 465     ALA a   204                                                      
REMARK 465     ARG a   205                                                      
REMARK 465     SER a   206                                                      
REMARK 465     ALA a   207                                                      
REMARK 465     HIS a   208                                                      
REMARK 465     SER a   209                                                      
REMARK 465     LYS a   210                                                      
REMARK 465     ILE a   211                                                      
REMARK 465     GLN a   212                                                      
REMARK 465     GLY a   213                                                      
REMARK 465     GLY a   214                                                      
REMARK 465     ARG a   215                                                      
REMARK 465     ASN a   216                                                      
REMARK 465     ALA a   217                                                      
REMARK 465     ALA a   218                                                      
REMARK 465     ASN a   219                                                      
REMARK 465     ILE a   220                                                      
REMARK 465     MET a   221                                                      
REMARK 465     ASP a   248                                                      
REMARK 465     SER a   249                                                      
REMARK 465     LEU a   250                                                      
REMARK 465     ALA a   251                                                      
REMARK 465     MET c     1                                                      
REMARK 465     ASN c     2                                                      
REMARK 465     ASN c     3                                                      
REMARK 465     ASN c     4                                                      
REMARK 465     SER c     5                                                      
REMARK 465     ARG c     6                                                      
REMARK 465     ASN c     7                                                      
REMARK 465     ASN c     8                                                      
REMARK 465     GLU c     9                                                      
REMARK 465     ASN c    10                                                      
REMARK 465     ARG c    11                                                      
REMARK 465     SER c    12                                                      
REMARK 465     THR c    13                                                      
REMARK 465     ILE c    14                                                      
REMARK 465     ASN c    15                                                      
REMARK 465     ARG c    16                                                      
REMARK 465     ASN c    17                                                      
REMARK 465     LYS c    18                                                      
REMARK 465     ARG c    19                                                      
REMARK 465     GLN c    20                                                      
REMARK 465     LEU c    21                                                      
REMARK 465     GLN c    22                                                      
REMARK 465     GLN c    23                                                      
REMARK 465     ALA c    24                                                      
REMARK 465     LYS c    25                                                      
REMARK 465     GLU c    26                                                      
REMARK 465     LYS c    27                                                      
REMARK 465     ASN c    28                                                      
REMARK 465     GLU c    29                                                      
REMARK 465     ASN c    30                                                      
REMARK 465     ILE c    31                                                      
REMARK 465     HIS c    32                                                      
REMARK 465     ILE c    33                                                      
REMARK 465     PRO c    34                                                      
REMARK 465     ARG c    35                                                      
REMARK 465     TYR c    36                                                      
REMARK 465     ILE c    37                                                      
REMARK 465     ARG c    38                                                      
REMARK 465     ASN c    39                                                      
REMARK 465     GLN c    40                                                      
REMARK 465     PRO c    41                                                      
REMARK 465     TRP c    42                                                      
REMARK 465     TYR c    43                                                      
REMARK 465     TYR c    44                                                      
REMARK 465     LYS c    45                                                      
REMARK 465     ASP c    46                                                      
REMARK 465     THR c    47                                                      
REMARK 465     PRO c    48                                                      
REMARK 465     LYS c    49                                                      
REMARK 465     GLU c    50                                                      
REMARK 465     GLN c    51                                                      
REMARK 465     GLU c    52                                                      
REMARK 465     GLY c    53                                                      
REMARK 465     LYS c    54                                                      
REMARK 465     LYS c    55                                                      
REMARK 465     PRO c    56                                                      
REMARK 465     GLY c    57                                                      
REMARK 465     ASN c    58                                                      
REMARK 465     ASP c    59                                                      
REMARK 465     ASP c    60                                                      
REMARK 465     THR c    61                                                      
REMARK 465     SER c    62                                                      
REMARK 465     THR c    63                                                      
REMARK 465     ALA c    64                                                      
REMARK 465     GLU c    65                                                      
REMARK 465     GLY c    66                                                      
REMARK 465     GLY c    67                                                      
REMARK 465     GLU c    68                                                      
REMARK 465     LYS c    69                                                      
REMARK 465     SER c    70                                                      
REMARK 465     ASP c    71                                                      
REMARK 465     TYR c    72                                                      
REMARK 465     LEU c    73                                                      
REMARK 465     VAL c    74                                                      
REMARK 465     HIS c    75                                                      
REMARK 465     HIS c    76                                                      
REMARK 465     ARG c    77                                                      
REMARK 465     GLN c    78                                                      
REMARK 465     LYS c    79                                                      
REMARK 465     ALA c    80                                                      
REMARK 465     LYS c    81                                                      
REMARK 465     GLY c    82                                                      
REMARK 465     GLY c    83                                                      
REMARK 465     ALA c    84                                                      
REMARK 465     LEU c    85                                                      
REMARK 465     ASP c    86                                                      
REMARK 465     ILE c    87                                                      
REMARK 465     ASP c    88                                                      
REMARK 465     ASN c    89                                                      
REMARK 465     ASN c    90                                                      
REMARK 465     SER c    91                                                      
REMARK 465     GLU c    92                                                      
REMARK 465     PRO c    93                                                      
REMARK 465     LYS c    94                                                      
REMARK 465     ILE c    95                                                      
REMARK 465     GLY c    96                                                      
REMARK 465     MET c    97                                                      
REMARK 465     GLY c    98                                                      
REMARK 465     ILE c    99                                                      
REMARK 465     LYS c   100                                                      
REMARK 465     ASP c   101                                                      
REMARK 465     GLU c   102                                                      
REMARK 465     PHE c   103                                                      
REMARK 465     LYS c   104                                                      
REMARK 465     LEU c   105                                                      
REMARK 465     ILE c   106                                                      
REMARK 465     ARG c   107                                                      
REMARK 465     PRO c   108                                                      
REMARK 465     GLN c   109                                                      
REMARK 465     LYS c   110                                                      
REMARK 465     MET c   111                                                      
REMARK 465     SER c   112                                                      
REMARK 465     VAL c   113                                                      
REMARK 465     ARG c   114                                                      
REMARK 465     ASP c   115                                                      
REMARK 465     SER c   116                                                      
REMARK 465     HIS c   117                                                      
REMARK 465     SER c   118                                                      
REMARK 465     LEU c   119                                                      
REMARK 465     SER c   120                                                      
REMARK 465     PHE c   121                                                      
REMARK 465     CYS c   122                                                      
REMARK 465     ARG c   123                                                      
REMARK 465     ASN c   124                                                      
REMARK 465     CYS c   125                                                      
REMARK 465     GLY c   126                                                      
REMARK 465     GLU c   127                                                      
REMARK 465     ALA c   128                                                      
REMARK 465     GLY c   129                                                      
REMARK 465     HIS c   130                                                      
REMARK 465     LYS c   131                                                      
REMARK 465     GLU c   132                                                      
REMARK 465     LYS c   133                                                      
REMARK 465     ASP c   134                                                      
REMARK 465     CYS c   135                                                      
REMARK 465     MET c   136                                                      
REMARK 465     GLU c   137                                                      
REMARK 465     LYS c   138                                                      
REMARK 465     PRO c   139                                                      
REMARK 465     ARG c   140                                                      
REMARK 465     LYS c   141                                                      
REMARK 465     MET c   142                                                      
REMARK 465     GLN c   143                                                      
REMARK 465     LYS c   144                                                      
REMARK 465     LEU c   145                                                      
REMARK 465     VAL c   146                                                      
REMARK 465     PRO c   147                                                      
REMARK 465     ASP c   148                                                      
REMARK 465     LEU c   149                                                      
REMARK 465     ASN c   150                                                      
REMARK 465     SER c   151                                                      
REMARK 465     GLN c   152                                                      
REMARK 465     LYS c   153                                                      
REMARK 465     ASN c   154                                                      
REMARK 465     ASN c   155                                                      
REMARK 465     GLY c   156                                                      
REMARK 465     THR c   157                                                      
REMARK 465     VAL c   158                                                      
REMARK 465     LEU c   159                                                      
REMARK 465     VAL c   160                                                      
REMARK 465     ARG c   161                                                      
REMARK 465     ALA c   162                                                      
REMARK 465     THR c   163                                                      
REMARK 465     ASP c   164                                                      
REMARK 465     ASP c   165                                                      
REMARK 465     ILE c   197                                                      
REMARK 465     LYS c   198                                                      
REMARK 465     GLY c   199                                                      
REMARK 465     LYS c   200                                                      
REMARK 465     ASP c   201                                                      
REMARK 465     LYS c   202                                                      
REMARK 465     SER c   203                                                      
REMARK 465     GLN c   204                                                      
REMARK 465     THR c   205                                                      
REMARK 465     ASP c   206                                                      
REMARK 465     GLU c   207                                                      
REMARK 465     THR c   208                                                      
REMARK 465     LEU c   209                                                      
REMARK 465     TRP c   210                                                      
REMARK 465     ASP c   211                                                      
REMARK 465     THR c   212                                                      
REMARK 465     ASP c   213                                                      
REMARK 465     GLU c   214                                                      
REMARK 465     LEU c   231                                                      
REMARK 465     LYS c   232                                                      
REMARK 465     LYS c   233                                                      
REMARK 465     ASP c   234                                                      
REMARK 465     ASP c   235                                                      
REMARK 465     ALA c   236                                                      
REMARK 465     ASP c   237                                                      
REMARK 465     ASN c   238                                                      
REMARK 465     SER c   239                                                      
REMARK 465     GLN c   240                                                      
REMARK 465     LEU c   241                                                      
REMARK 465     TYR c   242                                                      
REMARK 465     ARG c   243                                                      
REMARK 465     THR c   244                                                      
REMARK 465     SER c   245                                                      
REMARK 465     THR c   246                                                      
REMARK 465     ARG c   247                                                      
REMARK 465     LEU c   248                                                      
REMARK 465     ARG c   249                                                      
REMARK 465     GLU c   250                                                      
REMARK 465     ASP c   251                                                      
REMARK 465     LYS c   252                                                      
REMARK 465     ALA c   253                                                      
REMARK 465     ALA c   254                                                      
REMARK 465     TYR c   255                                                      
REMARK 465     LEU c   256                                                      
REMARK 465     ASN c   257                                                      
REMARK 465     ASP c   258                                                      
REMARK 465     ILE c   259                                                      
REMARK 465     ASN c   260                                                      
REMARK 465     SER c   261                                                      
REMARK 465     THR c   262                                                      
REMARK 465     GLU c   263                                                      
REMARK 465     SER c   264                                                      
REMARK 465     ASN c   265                                                      
REMARK 465     TYR c   266                                                      
REMARK 465     ASP c   267                                                      
REMARK 465     PRO c   268                                                      
REMARK 465     LYS c   269                                                      
REMARK 465     SER c   270                                                      
REMARK 465     ARG c   271                                                      
REMARK 465     LEU c   272                                                      
REMARK 465     TYR c   273                                                      
REMARK 465     LYS c   274                                                      
REMARK 465     THR c   275                                                      
REMARK 465     GLU c   276                                                      
REMARK 465     THR c   277                                                      
REMARK 465     LEU c   278                                                      
REMARK 465     GLY c   279                                                      
REMARK 465     ALA c   280                                                      
REMARK 465     VAL c   281                                                      
REMARK 465     ASP c   282                                                      
REMARK 465     GLU c   283                                                      
REMARK 465     LYS c   284                                                      
REMARK 465     SER c   285                                                      
REMARK 465     LYS c   286                                                      
REMARK 465     MET c   287                                                      
REMARK 465     PHE c   288                                                      
REMARK 465     ARG c   289                                                      
REMARK 465     ARG c   290                                                      
REMARK 465     HIS c   291                                                      
REMARK 465     LEU c   292                                                      
REMARK 465     LYS c   349                                                      
REMARK 465     GLN c   350                                                      
REMARK 465     PRO c   351                                                      
REMARK 465     LYS c   352                                                      
REMARK 465     ILE c   353                                                      
REMARK 465     VAL c   354                                                      
REMARK 465     SER c   355                                                      
REMARK 465     ILE c   356                                                      
REMARK 465     GLY c   357                                                      
REMARK 465     ASP c   358                                                      
REMARK 465     LEU c   359                                                      
REMARK 465     GLU c   360                                                      
REMARK 465     ALA c   361                                                      
REMARK 465     ARG c   362                                                      
REMARK 465     LYS c   363                                                      
REMARK 465     VAL c   364                                                      
REMARK 465     ASP c   365                                                      
REMARK 465     GLY c   366                                                      
REMARK 465     THR c   367                                                      
REMARK 465     LYS c   368                                                      
REMARK 465     GLN c   369                                                      
REMARK 465     SER c   370                                                      
REMARK 465     GLU c   371                                                      
REMARK 465     GLU c   372                                                      
REMARK 465     GLN c   373                                                      
REMARK 465     ARG c   374                                                      
REMARK 465     ASN c   375                                                      
REMARK 465     HIS c   376                                                      
REMARK 465     LEU c   377                                                      
REMARK 465     LYS c   378                                                      
REMARK 465     ASP c   379                                                      
REMARK 465     LEU c   380                                                      
REMARK 465     TYR c   381                                                      
REMARK 465     GLY c   382                                                      
REMARK 465     MET o     1                                                      
REMARK 465     GLY o     2                                                      
REMARK 465     LEU o     3                                                      
REMARK 465     VAL o     4                                                      
REMARK 465     ASP o     5                                                      
REMARK 465     GLY o     6                                                      
REMARK 465     TYR o     7                                                      
REMARK 465     ASP o     8                                                      
REMARK 465     THR o     9                                                      
REMARK 465     SER o    10                                                      
REMARK 465     SER o    11                                                      
REMARK 465     ASP o    12                                                      
REMARK 465     SER o    13                                                      
REMARK 465     ASP o    14                                                      
REMARK 465     LEU o    15                                                      
REMARK 465     ASN o    16                                                      
REMARK 465     PHE o    17                                                      
REMARK 465     ASP o    18                                                      
REMARK 465     GLU o    19                                                      
REMARK 465     GLY o    20                                                      
REMARK 465     LYS o    21                                                      
REMARK 465     SER o    22                                                      
REMARK 465     VAL o    23                                                      
REMARK 465     HIS o    24                                                      
REMARK 465     GLU o    25                                                      
REMARK 465     LYS o    26                                                      
REMARK 465     LYS o    27                                                      
REMARK 465     ASN o    28                                                      
REMARK 465     GLY o    29                                                      
REMARK 465     ASN o    30                                                      
REMARK 465     LEU o    31                                                      
REMARK 465     HIS o    32                                                      
REMARK 465     GLU o    33                                                      
REMARK 465     ASP o    34                                                      
REMARK 465     THR o    35                                                      
REMARK 465     SER o    36                                                      
REMARK 465     TYR o    37                                                      
REMARK 465     GLU o    38                                                      
REMARK 465     PRO o    39                                                      
REMARK 465     SER o    40                                                      
REMARK 465     SER o    41                                                      
REMARK 465     ASN o    42                                                      
REMARK 465     ASN o    43                                                      
REMARK 465     ILE o    44                                                      
REMARK 465     HIS o    45                                                      
REMARK 465     LYS o    46                                                      
REMARK 465     ARG o    47                                                      
REMARK 465     LYS o    48                                                      
REMARK 465     SER o    49                                                      
REMARK 465     HIS o    50                                                      
REMARK 465     SER o    74                                                      
REMARK 465     SER o    75                                                      
REMARK 465     ASP o    76                                                      
REMARK 465     ASP o    77                                                      
REMARK 465     GLU o    78                                                      
REMARK 465     THR o    79                                                      
REMARK 465     SER o    80                                                      
REMARK 465     GLN o    81                                                      
REMARK 465     ALA o    82                                                      
REMARK 465     SER o    83                                                      
REMARK 465     GLU o    84                                                      
REMARK 465     THR o    85                                                      
REMARK 465     GLN o    86                                                      
REMARK 465     LYS o    87                                                      
REMARK 465     GLU o    88                                                      
REMARK 465     ASP o    89                                                      
REMARK 465     GLN o    90                                                      
REMARK 465     ASP o    91                                                      
REMARK 465     ILE o    92                                                      
REMARK 465     PHE o    93                                                      
REMARK 465     VAL o    94                                                      
REMARK 465     HIS o    95                                                      
REMARK 465     ALA o    96                                                      
REMARK 465     LEU o    97                                                      
REMARK 465     ALA o    98                                                      
REMARK 465     GLU o    99                                                      
REMARK 465     ASP o   100                                                      
REMARK 465     ASN o   101                                                      
REMARK 465     LEU o   102                                                      
REMARK 465     ASP o   103                                                      
REMARK 465     SER o   104                                                      
REMARK 465     GLU o   105                                                      
REMARK 465     GLN o   106                                                      
REMARK 465     ILE o   107                                                      
REMARK 465     GLU o   108                                                      
REMARK 465     VAL o   109                                                      
REMARK 465     GLU o   110                                                      
REMARK 465     GLU o   111                                                      
REMARK 465     VAL o   112                                                      
REMARK 465     SER o   113                                                      
REMARK 465     HIS o   114                                                      
REMARK 465     PHE o   115                                                      
REMARK 465     TYR o   116                                                      
REMARK 465     GLY o   117                                                      
REMARK 465     LYS o   118                                                      
REMARK 465     SER o   119                                                      
REMARK 465     GLU o   120                                                      
REMARK 465     LYS o   121                                                      
REMARK 465     ASP o   122                                                      
REMARK 465     TYR o   123                                                      
REMARK 465     GLN o   124                                                      
REMARK 465     GLY o   125                                                      
REMARK 465     ARG o   126                                                      
REMARK 465     GLY o   127                                                      
REMARK 465     TYR o   128                                                      
REMARK 465     LEU o   129                                                      
REMARK 465     TYR o   130                                                      
REMARK 465     PRO o   131                                                      
REMARK 465     PRO o   132                                                      
REMARK 465     ASN o   133                                                      
REMARK 465     ASP o   134                                                      
REMARK 465     VAL o   135                                                      
REMARK 465     ASP o   136                                                      
REMARK 465     VAL o   137                                                      
REMARK 465     ASP o   138                                                      
REMARK 465     LEU o   139                                                      
REMARK 465     ARG o   140                                                      
REMARK 465     GLU o   141                                                      
REMARK 465     GLU o   142                                                      
REMARK 465     ARG o   143                                                      
REMARK 465     ILE o   144                                                      
REMARK 465     SER o   145                                                      
REMARK 465     PHE o   146                                                      
REMARK 465     ARG o   147                                                      
REMARK 465     CYS o   148                                                      
REMARK 465     TYR o   149                                                      
REMARK 465     LEU o   150                                                      
REMARK 465     PRO o   151                                                      
REMARK 465     LYS o   152                                                      
REMARK 465     LYS o   153                                                      
REMARK 465     VAL o   154                                                      
REMARK 465     ALA o   390                                                      
REMARK 465     PHE o   391                                                      
REMARK 465     SER o   392                                                      
REMARK 465     GLY o   393                                                      
REMARK 465     ASP o   394                                                      
REMARK 465     GLY o   395                                                      
REMARK 465     LYS o   421A                                                     
REMARK 465     ILE o   421B                                                     
REMARK 465     PRO o   421C                                                     
REMARK 465     GLY o   421D                                                     
REMARK 465     ASP o   455                                                      
REMARK 465     MET y     1                                                      
REMARK 465     ASP y     2                                                      
REMARK 465     PHE y     3                                                      
REMARK 465     TYR y     4                                                      
REMARK 465     LYS y     5                                                      
REMARK 465     LEU y     6                                                      
REMARK 465     ASP y     7                                                      
REMARK 465     GLU y     8                                                      
REMARK 465     LYS y     9                                                      
REMARK 465     LEU y    10                                                      
REMARK 465     LYS y    11                                                      
REMARK 465     GLU y    12                                                      
REMARK 465     LEU y    13                                                      
REMARK 465     LYS y    14                                                      
REMARK 465     ARG y    15                                                      
REMARK 465     LYS y    16                                                      
REMARK 465     ARG y    17                                                      
REMARK 465     VAL y    18                                                      
REMARK 465     ASP y    19                                                      
REMARK 465     VAL y    20                                                      
REMARK 465     SER y    21                                                      
REMARK 465     ILE y    22                                                      
REMARK 465     LYS y    23                                                      
REMARK 465     SER y    24                                                      
REMARK 465     ARG y    25                                                      
REMARK 465     LYS y    26                                                      
REMARK 465     LEU y    27                                                      
REMARK 465     ALA y    28                                                      
REMARK 465     ASP y    29                                                      
REMARK 465     ARG y    30                                                      
REMARK 465     GLU y    31                                                      
REMARK 465     ILE y    32                                                      
REMARK 465     GLN y    33                                                      
REMARK 465     GLU y    34                                                      
REMARK 465     VAL y    35                                                      
REMARK 465     SER y    36                                                      
REMARK 465     ALA y    37                                                      
REMARK 465     ASN y    38                                                      
REMARK 465     ARG y    39                                                      
REMARK 465     LYS y    40                                                      
REMARK 465     PRO y    41                                                      
REMARK 465     ARG y    42                                                      
REMARK 465     VAL y    43                                                      
REMARK 465     TYR y    44                                                      
REMARK 465     SER y    45                                                      
REMARK 465     MET y    46                                                      
REMARK 465     GLU y    47                                                      
REMARK 465     ASP y    48                                                      
REMARK 465     VAL y    49                                                      
REMARK 465     ASN y    50                                                      
REMARK 465     ASP y    51                                                      
REMARK 465     ALA y    52                                                      
REMARK 465     ASP y    53                                                      
REMARK 465     GLU y    54                                                      
REMARK 465     SER y    55                                                      
REMARK 465     VAL y    56                                                      
REMARK 465     GLY y    57                                                      
REMARK 465     ASP y    58                                                      
REMARK 465     THR y    59                                                      
REMARK 465     GLU y    60                                                      
REMARK 465     SER y    61                                                      
REMARK 465     PRO y    62                                                      
REMARK 465     GLU y    63                                                      
REMARK 465     LYS y    64                                                      
REMARK 465     GLU y    65                                                      
REMARK 465     LYS y    66                                                      
REMARK 465     ALA y    67                                                      
REMARK 465     PHE y    68                                                      
REMARK 465     HIS y    69                                                      
REMARK 465     TYR y    70                                                      
REMARK 465     THR y    71                                                      
REMARK 465     VAL y    72                                                      
REMARK 465     GLN y    73                                                      
REMARK 465     GLU y    74                                                      
REMARK 465     TYR y    75                                                      
REMARK 465     ASP y    76                                                      
REMARK 465     ALA y    77                                                      
REMARK 465     TRP y    78                                                      
REMARK 465     GLU y    79                                                      
REMARK 465     ARG y    80                                                      
REMARK 465     ARG y    81                                                      
REMARK 465     HIS y    82                                                      
REMARK 465     PRO y    83                                                      
REMARK 465     GLN y    84                                                      
REMARK 465     GLY y    85                                                      
REMARK 465     LYS y    86                                                      
REMARK 465     THR y    87                                                      
REMARK 465     GLY y    88                                                      
REMARK 465     GLN y    89                                                      
REMARK 465     SER y    90                                                      
REMARK 465     GLN y    91                                                      
REMARK 465     ARG y    92                                                      
REMARK 465     GLY y    93                                                      
REMARK 465     GLY y    94                                                      
REMARK 465     THR y   116                                                      
REMARK 465     GLN y   117                                                      
REMARK 465     ASN y   118                                                      
REMARK 465     SER y   119                                                      
REMARK 465     SER y   120                                                      
REMARK 465     LYS y   121                                                      
REMARK 465     GLN y   122                                                      
REMARK 465     ASP y   123                                                      
REMARK 465     SER y   124                                                      
REMARK 465     SER y   125                                                      
REMARK 465     ALA y   126                                                      
REMARK 465     ASP y   127                                                      
REMARK 465     GLU y   128                                                      
REMARK 465     GLU y   129                                                      
REMARK 465     ASP y   130                                                      
REMARK 465     ASN y   131                                                      
REMARK 465     LYS y   132                                                      
REMARK 465     ASN y   133                                                      
REMARK 465     VAL y   134                                                      
REMARK 465     PRO y   135                                                      
REMARK 465     LYS y   136                                                      
REMARK 465     LYS y   137                                                      
REMARK 465     GLY y   138                                                      
REMARK 465     ARG y   139                                                      
REMARK 465     ILE y   140                                                      
REMARK 465     GLY y   141                                                      
REMARK 465     LYS y   187                                                      
REMARK 465     THR y   188                                                      
REMARK 465     LEU y   189                                                      
REMARK 465     TYR y   190                                                      
REMARK 465     GLY y   191                                                      
REMARK 465     VAL y   192                                                      
REMARK 465     GLU y   193                                                      
REMARK 465     SER y   211                                                      
REMARK 465     LYS y   212                                                      
REMARK 465     GLY y   213                                                      
REMARK 465     SER y   214                                                      
REMARK 465     GLU y   215                                                      
REMARK 465     MET b     1                                                      
REMARK 465     SER b     2                                                      
REMARK 465     LYS b     3                                                      
REMARK 465     THR b    56                                                      
REMARK 465     GLN b    57                                                      
REMARK 465     LEU b    58                                                      
REMARK 465     ASP b    59                                                      
REMARK 465     LYS b    60                                                      
REMARK 465     LEU b    61                                                      
REMARK 465     ARG b    62                                                      
REMARK 465     PRO b    63                                                      
REMARK 465     ARG b    64                                                      
REMARK 465     LYS b    65                                                      
REMARK 465     ASP b    66                                                      
REMARK 465     SER b    67                                                      
REMARK 465     LYS b    68                                                      
REMARK 465     ASP b    69                                                      
REMARK 465     GLY b    70                                                      
REMARK 465     THR b    71                                                      
REMARK 465     THR b    72                                                      
REMARK 465     LEU b    73                                                      
REMARK 465     ASN b    74                                                      
REMARK 465     LEU b   103                                                      
REMARK 465     SER b   104                                                      
REMARK 465     LYS b   105                                                      
REMARK 465     LYS b   106                                                      
REMARK 465     GLU b   107                                                      
REMARK 465     ARG b   108                                                      
REMARK 465     LEU b   109                                                      
REMARK 465     VAL b   110                                                      
REMARK 465     ARG b   111                                                      
REMARK 465     ASP b   112                                                      
REMARK 465     LYS b   113                                                      
REMARK 465     LYS b   114                                                      
REMARK 465     GLU b   115                                                      
REMARK 465     LYS b   116                                                      
REMARK 465     LYS b   117                                                      
REMARK 465     GLN b   118                                                      
REMARK 465     ALA b   119                                                      
REMARK 465     GLN b   120                                                      
REMARK 465     LYS b   121                                                      
REMARK 465     GLN b   122                                                      
REMARK 465     THR b   123                                                      
REMARK 465     LYS b   124                                                      
REMARK 465     LEU b   125                                                      
REMARK 465     ARG b   126                                                      
REMARK 465     LYS b   127                                                      
REMARK 465     GLU b   128                                                      
REMARK 465     LYS b   129                                                      
REMARK 465     GLU b   130                                                      
REMARK 465     LYS b   131                                                      
REMARK 465     LYS b   132                                                      
REMARK 465     PRO b   133                                                      
REMARK 465     GLY b   134                                                      
REMARK 465     LYS b   135                                                      
REMARK 465     ILE b   136                                                      
REMARK 465     ALA b   137                                                      
REMARK 465     LYS b   138                                                      
REMARK 465     PRO b   139                                                      
REMARK 465     ASN b   140                                                      
REMARK 465     THR b   141                                                      
REMARK 465     ALA b   142                                                      
REMARK 465     ASN b   143                                                      
REMARK 465     ALA b   144                                                      
REMARK 465     LYS b   145                                                      
REMARK 465     HIS b   146                                                      
REMARK 465     THR b   147                                                      
REMARK 465     SER b   148                                                      
REMARK 465     SER b   149                                                      
REMARK 465     ASN b   150                                                      
REMARK 465     SER b   151                                                      
REMARK 465     ARG b   152                                                      
REMARK 465     GLU b   153                                                      
REMARK 465     ILE b   154                                                      
REMARK 465     ALA b   155                                                      
REMARK 465     GLN b   156                                                      
REMARK 465     PRO b   157                                                      
REMARK 465     SER b   158                                                      
REMARK 465     SER b   159                                                      
REMARK 465     SER b   160                                                      
REMARK 465     ARG b   161                                                      
REMARK 465     TYR b   162                                                      
REMARK 465     ASN b   163                                                      
REMARK 465     GLY b   164                                                      
REMARK 465     GLY b   165                                                      
REMARK 465     ASN b   166                                                      
REMARK 465     ASP b   167                                                      
REMARK 465     ASN b   168                                                      
REMARK 465     ILE b   169                                                      
REMARK 465     GLY b   170                                                      
REMARK 465     ALA b   171                                                      
REMARK 465     ASN b   172                                                      
REMARK 465     ARG b   173                                                      
REMARK 465     SER b   174                                                      
REMARK 465     ARG b   175                                                      
REMARK 465     PHE b   176                                                      
REMARK 465     ASN b   177                                                      
REMARK 465     ASN b   178                                                      
REMARK 465     GLU b   179                                                      
REMARK 465     ALA b   180                                                      
REMARK 465     PRO b   181                                                      
REMARK 465     PRO b   182                                                      
REMARK 465     GLN b   183                                                      
REMARK 465     THR b   184                                                      
REMARK 465     ARG b   185                                                      
REMARK 465     LYS b   186                                                      
REMARK 465     PHE b   187                                                      
REMARK 465     GLN b   188                                                      
REMARK 465     PRO b   189                                                      
REMARK 465     PRO b   190                                                      
REMARK 465     PRO b   191                                                      
REMARK 465     GLY b   192                                                      
REMARK 465     PHE b   193                                                      
REMARK 465     LYS b   194                                                      
REMARK 465     ARG b   195                                                      
REMARK 465     LYS b   196                                                      
REMARK 465     MET d     1                                                      
REMARK 465     THR d     2                                                      
REMARK 465     MET d     3                                                      
REMARK 465     LYS d    86                                                      
REMARK 465     ASN d    87                                                      
REMARK 465     SER d    88                                                      
REMARK 465     SER d    89                                                      
REMARK 465     ARG d    90                                                      
REMARK 465     PRO d    91                                                      
REMARK 465     MET d    92                                                      
REMARK 465     PRO d    93                                                      
REMARK 465     PRO d    94                                                      
REMARK 465     ILE d    95                                                      
REMARK 465     ARG d    96                                                      
REMARK 465     GLY d    97                                                      
REMARK 465     PRO d    98                                                      
REMARK 465     LYS d    99                                                      
REMARK 465     ARG d   100                                                      
REMARK 465     ARG d   101                                                      
REMARK 465     MET e     1                                                      
REMARK 465     SER e     2                                                      
REMARK 465     ASN e     3                                                      
REMARK 465     LYS e     4                                                      
REMARK 465     VAL e     5                                                      
REMARK 465     LYS e     6                                                      
REMARK 465     THR e     7                                                      
REMARK 465     LYS e     8                                                      
REMARK 465     ALA e     9                                                      
REMARK 465     ALA e    65                                                      
REMARK 465     ASP e    66                                                      
REMARK 465     GLY e    67                                                      
REMARK 465     LYS e    68                                                      
REMARK 465     GLU e    69                                                      
REMARK 465     ASP e    70                                                      
REMARK 465     VAL e    71                                                      
REMARK 465     GLU e    72                                                      
REMARK 465     ALA e    93                                                      
REMARK 465     ASP e    94                                                      
REMARK 465     MET f     1                                                      
REMARK 465     SER f     2                                                      
REMARK 465     GLU f     3                                                      
REMARK 465     SER f     4                                                      
REMARK 465     SER f     5                                                      
REMARK 465     ASP f     6                                                      
REMARK 465     ILE f     7                                                      
REMARK 465     SER f     8                                                      
REMARK 465     ALA f     9                                                      
REMARK 465     MET f    10                                                      
REMARK 465     GLN f    11                                                      
REMARK 465     LEU f    84                                                      
REMARK 465     PRO f    85                                                      
REMARK 465     ASN f    86                                                      
REMARK 465     MET g     1                                                      
REMARK 465     ASN g    47                                                      
REMARK 465     GLY g    48                                                      
REMARK 465     GLU g    49                                                      
REMARK 465     ASP g    50                                                      
REMARK 465     PRO g    51                                                      
REMARK 465     ALA g    52                                                      
REMARK 465     ILE g    77                                                      
REMARK 465     GLN h    49                                                      
REMARK 465     PRO h    50                                                      
REMARK 465     ARG h    51                                                      
REMARK 465     LEU h    52                                                      
REMARK 465     ASN h    53                                                      
REMARK 465     LYS h    54                                                      
REMARK 465     LEU h    55                                                      
REMARK 465     ASN h    56                                                      
REMARK 465     SER h    57                                                      
REMARK 465     ASN h    58                                                      
REMARK 465     GLY h    59                                                      
REMARK 465     ILE h    60                                                      
REMARK 465     ALA h    61                                                      
REMARK 465     MET h    62                                                      
REMARK 465     ALA h    63                                                      
REMARK 465     SER h    64                                                      
REMARK 465     LEU h    65                                                      
REMARK 465     TYR h    66                                                      
REMARK 465     LEU h    67                                                      
REMARK 465     THR h    68                                                      
REMARK 465     GLY h    69                                                      
REMARK 465     GLY h    70                                                      
REMARK 465     GLN h    71                                                      
REMARK 465     GLN h    72                                                      
REMARK 465     PRO h    73                                                      
REMARK 465     THR h    74                                                      
REMARK 465     ALA h    75                                                      
REMARK 465     GLN h   110                                                      
REMARK 465     LYS h   111                                                      
REMARK 465     GLN h   112                                                      
REMARK 465     LEU h   113                                                      
REMARK 465     ASN h   114                                                      
REMARK 465     SER h   115                                                      
REMARK 465     LEU h   116                                                      
REMARK 465     ARG h   117                                                      
REMARK 465     ARG h   118                                                      
REMARK 465     SER h   119                                                      
REMARK 465     GLY h   120                                                      
REMARK 465     GLN h   121                                                      
REMARK 465     ILE h   122                                                      
REMARK 465     ALA h   123                                                      
REMARK 465     ASN h   124                                                      
REMARK 465     ASP h   125                                                      
REMARK 465     PRO h   126                                                      
REMARK 465     SER h   127                                                      
REMARK 465     LYS h   128                                                      
REMARK 465     LYS h   129                                                      
REMARK 465     ARG h   130                                                      
REMARK 465     ARG h   131                                                      
REMARK 465     ARG h   132                                                      
REMARK 465     ASP h   133                                                      
REMARK 465     PHE h   134                                                      
REMARK 465     GLY h   135                                                      
REMARK 465     ALA h   136                                                      
REMARK 465     PRO h   137                                                      
REMARK 465     ALA h   138                                                      
REMARK 465     ASN h   139                                                      
REMARK 465     LYS h   140                                                      
REMARK 465     ARG h   141                                                      
REMARK 465     PRO h   142                                                      
REMARK 465     ARG h   143                                                      
REMARK 465     ARG h   144                                                      
REMARK 465     GLY h   145                                                      
REMARK 465     LEU h   146                                                      
REMARK 465     MET j     1                                                      
REMARK 465     SER j     2                                                      
REMARK 465     SER j     3                                                      
REMARK 465     GLN j     4                                                      
REMARK 465     ILE j     5                                                      
REMARK 465     ILE j     6                                                      
REMARK 465     ASP j     7                                                      
REMARK 465     ARG j     8                                                      
REMARK 465     PRO j     9                                                      
REMARK 465     LYS j    10                                                      
REMARK 465     HIS j    11                                                      
REMARK 465     GLU j    12                                                      
REMARK 465     LEU j    13                                                      
REMARK 465     SER j    14                                                      
REMARK 465     VAL j   109                                                      
REMARK 465     GLU j   110                                                      
REMARK 470                                                                      
REMARK 470 MISSING ATOM                                                         
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;           
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;          
REMARK 470 I=INSERTION CODE):                                                   
REMARK 470   M RES CSSEQI  ATOMS                                                
REMARK 470     LEU A 127    CG   CD1  CD2                                       
REMARK 470     GLU A 133    CG   CD   OE1  OE2                                  
REMARK 470     MET A 153    CG   SD   CE                                        
REMARK 470     GLU A 204    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 227    CG   CD   OE1  OE2                                  
REMARK 470     ASP A 230    CG   OD1  OD2                                       
REMARK 470     ASP A 245    CG   OD1  OD2                                       
REMARK 470     GLU A 246    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 252    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 256    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 274    CG   CD   OE1  OE2                                  
REMARK 470     LYS A 277    CG   CD   CE   NZ                                   
REMARK 470     GLU A 287    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 288    CG   CD   OE1  OE2                                  
REMARK 470     ASP A 289    CG   OD1  OD2                                       
REMARK 470     LYS A 291    CG   CD   CE   NZ                                   
REMARK 470     ASP A 320    CG   OD1  OD2                                       
REMARK 470     GLU A 321    CG   CD   OE1  OE2                                  
REMARK 470     ASP A 324    CG   OD1  OD2                                       
REMARK 470     GLU A 353    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 382    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 415    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 416    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 456    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 464    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 465    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 466    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 467    CG   CD   OE1  OE2                                  
REMARK 470     LYS A 474    CG   CD   CE   NZ                                   
REMARK 470     ASP A 511    CG   OD1  OD2                                       
REMARK 470     GLU A 512    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 513    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 533    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 566    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 609    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 735    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 740    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 768    CG   CD   OE1  OE2                                  
REMARK 470     GLN A 776    CG   CD   OE1  NE2                                  
REMARK 470     ASP A 800    CG   OD1  OD2                                       
REMARK 470     LYS A 810    CG   CD   CE   NZ                                   
REMARK 470     GLU A 813    CG   CD   OE1  OE2                                  
REMARK 470     ASP A 821    CG   OD1  OD2                                       
REMARK 470     GLU A 862    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 873    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 877    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 878    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 888    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 891    CG   CD   OE1  OE2                                  
REMARK 470     ASP A 918    CG   OD1  OD2                                       
REMARK 470     ASP A 921    CG   OD1  OD2                                       
REMARK 470     GLU A 988    CG   CD   OE1  OE2                                  
REMARK 470     ASP A 992    CG   OD1  OD2                                       
REMARK 470     LYS A1014    CG   CD   CE   NZ                                   
REMARK 470     GLU A1037    CG   CD   OE1  OE2                                  
REMARK 470     ASP A1040    CG   OD1  OD2                                       
REMARK 470     SER A1042    OG                                                  
REMARK 470     ARG A1043    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLN A1045    CG   CD   OE1  NE2                                  
REMARK 470     LYS A1148    CG   CD   CE   NZ                                   
REMARK 470     LYS A1150    CG   CD   CE   NZ                                   
REMARK 470     GLU A1151    CG   CD   OE1  OE2                                  
REMARK 470     ASP A1166    CG   OD1  OD2                                       
REMARK 470     GLU A1176    CG   CD   OE1  OE2                                  
REMARK 470     ASP A1177    CG   OD1  OD2                                       
REMARK 470     GLU A1178    CG   CD   OE1  OE2                                  
REMARK 470     GLU A1180    CG   CD   OE1  OE2                                  
REMARK 470     GLU A1181    CG   CD   OE1  OE2                                  
REMARK 470     ASP A1184    CG   OD1  OD2                                       
REMARK 470     GLU A1185    CG   CD   OE1  OE2                                  
REMARK 470     LEU A1187    CG   CD1  CD2                                       
REMARK 470     GLU A1189    CG   CD   OE1  OE2                                  
REMARK 470     ASP A1192    CG   OD1  OD2                                       
REMARK 470     ASN A1194    CG   OD1  ND2                                       
REMARK 470     PHE A1195    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLU A1196    CG   CD   OE1  OE2                                  
REMARK 470     LYS A1209    CG   CD   CE   NZ                                   
REMARK 470     ASP A1210    CG   OD1  OD2                                       
REMARK 470     LYS A1242    CG   CD   CE   NZ                                   
REMARK 470     GLU A1244    CG   CD   OE1  OE2                                  
REMARK 470     ASN A1245    CG   OD1  ND2                                       
REMARK 470     LYS A1253    CG   CD   CE   NZ                                   
REMARK 470     ASN A1254    CG   OD1  ND2                                       
REMARK 470     MET A1275    CG   SD   CE                                        
REMARK 470     GLU A1276    CG   CD   OE1  OE2                                  
REMARK 470     ASN A1281    CG   OD1  ND2                                       
REMARK 470     ASP A1290    CG   OD1  OD2                                       
REMARK 470     GLU A1291    CG   CD   OE1  OE2                                  
REMARK 470     ARG A1292    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS A1294    CG   CD   CE   NZ                                   
REMARK 470     GLU A1307    CG   CD   OE1  OE2                                  
REMARK 470     GLU A1354    CG   CD   OE1  OE2                                  
REMARK 470     ASN A1376    CG   OD1  ND2                                       
REMARK 470     ASP A1411    CG   OD1  OD2                                       
REMARK 470     LEU A1412    CG   CD1  CD2                                       
REMARK 470     GLU A1432    CG   CD   OE1  OE2                                  
REMARK 470     GLU A1571    CG   CD   OE1  OE2                                  
REMARK 470     GLN A1600    CB   CG   CD   OE1  NE2                             
REMARK 470     GLU A1659    CG   CD   OE1  OE2                                  
REMARK 470     ASP A1664    CG   OD1  OD2                                       
REMARK 470     GLU A1679    CG   CD   OE1  OE2                                  
REMARK 470     GLU A1684    CG   CD   OE1  OE2                                  
REMARK 470     GLU A1704    CG   CD   OE1  OE2                                  
REMARK 470     ASP A1762    CG   OD1  OD2                                       
REMARK 470     GLU A1832    CG   CD   OE1  OE2                                  
REMARK 470     GLU A1842    CG   CD   OE1  OE2                                  
REMARK 470     ASP A1847    CG   OD1  OD2                                       
REMARK 470     ASP A1853    CG   OD1  OD2                                       
REMARK 470     ASP A1854    CG   OD1  OD2                                       
REMARK 470     GLU A1915    CG   CD   OE1  OE2                                  
REMARK 470     GLU A1916    CG   CD   OE1  OE2                                  
REMARK 470     LYS A1926    CG   CD   CE   NZ                                   
REMARK 470     GLU A1927    CG   CD   OE1  OE2                                  
REMARK 470     GLU A1928    CG   CD   OE1  OE2                                  
REMARK 470     ASP A1950    CG   OD1  OD2                                       
REMARK 470     GLU A1960    CG   CD   OE1  OE2                                  
REMARK 470     ARG A2007    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS A2016    CG   CD   CE   NZ                                   
REMARK 470     GLU A2019    CG   CD   OE1  OE2                                  
REMARK 470     GLU A2020    CG   CD   OE1  OE2                                  
REMARK 470     LYS A2023    CG   CD   CE   NZ                                   
REMARK 470     MET A2024    CG   SD   CE                                        
REMARK 470     THR A2044    OG1  CG2                                            
REMARK 470     ASP A2045    CG   OD1  OD2                                       
REMARK 470     GLU A2046    CG   CD   OE1  OE2                                  
REMARK 470     ILE A2049    CG1  CG2  CD1                                       
REMARK 470     THR A2050    OG1  CG2                                            
REMARK 470     ILE A2051    CG1  CG2  CD1                                       
REMARK 470     GLU A2052    CG   CD   OE1  OE2                                  
REMARK 470     SER A2053    OG                                                  
REMARK 470     GLN A2054    CG   CD   OE1  NE2                                  
REMARK 470     MET A2055    CG   SD   CE                                        
REMARK 470     ARG A2056    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP A2057    CG   OD1  OD2                                       
REMARK 470     LEU A2058    CG   CD1  CD2                                       
REMARK 470     ILE A2059    CG1  CG2  CD1                                       
REMARK 470     LEU A2060    CG   CD1  CD2                                       
REMARK 470     THR A2061    OG1  CG2                                            
REMARK 470     GLU A2062    CG   CD   OE1  OE2                                  
REMARK 470     TYR A2063    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ARG A2065    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS A2066    CG   CD   CE   NZ                                   
REMARK 470     TYR A2067    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ASN A2068    CG   OD1  ND2                                       
REMARK 470     VAL A2069    CG1  CG2                                            
REMARK 470     ASN A2070    CG   OD1  ND2                                       
REMARK 470     SER A2072    OG                                                  
REMARK 470     LEU A2074    CG   CD1  CD2                                       
REMARK 470     THR A2075    OG1  CG2                                            
REMARK 470     GLN A2076    CG   CD   OE1  NE2                                  
REMARK 470     THR A2077    OG1  CG2                                            
REMARK 470     GLU A2078    CG   CD   OE1  OE2                                  
REMARK 470     LYS A2080    CG   CD   CE   NZ                                   
REMARK 470     ASP A2081    CG   OD1  OD2                                       
REMARK 470     LEU A2084    CG   CD1  CD2                                       
REMARK 470     GLN A2086    CG   CD   OE1  NE2                                  
REMARK 470     ILE A2088    CG1  CG2  CD1                                       
REMARK 470     LYS A2094    CG   CD   CE   NZ                                   
REMARK 470     ARG A2095    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLN A2096    CG   CD   OE1  NE2                                  
REMARK 470     LYS A2097    CG   CD   CE   NZ                                   
REMARK 470     MET A2098    CG   SD   CE                                        
REMARK 470     GLU A2100    CG   CD   OE1  OE2                                  
REMARK 470     GLN C  84    CG   CD   OE1  NE2                                  
REMARK 470     GLN C  87    CG   CD   OE1  NE2                                  
REMARK 470     GLU C  92    CG   CD   OE1  OE2                                  
REMARK 470     ARG C  97    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     THR C  98    OG1  CG2                                            
REMARK 470     LYS C  99    CG   CD   CE   NZ                                   
REMARK 470     LEU C 100    CG   CD1  CD2                                       
REMARK 470     GLN C 101    CG   CD   OE1  NE2                                  
REMARK 470     LYS C 111    CG   CD   CE   NZ                                   
REMARK 470     ASP C 121    CG   OD1  OD2                                       
REMARK 470     GLU C 131    CG   CD   OE1  OE2                                  
REMARK 470     ASP C 151    CG   OD1  OD2                                       
REMARK 470     GLU C 184    CG   CD   OE1  OE2                                  
REMARK 470     ASP C 186    CG   OD1  OD2                                       
REMARK 470     ASP C 202    CG   OD1  OD2                                       
REMARK 470     GLU C 204    CG   CD   OE1  OE2                                  
REMARK 470     ASP C 214    CG   OD1  OD2                                       
REMARK 470     GLU C 224    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 243    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 250    CG   CD   OE1  OE2                                  
REMARK 470     LYS C 258    CG   CD   CE   NZ                                   
REMARK 470     ASP C 271    CG   OD1  OD2                                       
REMARK 470     ASP C 276    CG   OD1  OD2                                       
REMARK 470     LYS C 325    CG   CD   CE   NZ                                   
REMARK 470     GLU C 326    CG   CD   OE1  OE2                                  
REMARK 470     LYS C 340    CG   CD   CE   NZ                                   
REMARK 470     LYS C 356    CG   CD   CE   NZ                                   
REMARK 470     GLU C 365    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 375    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 392    CG   CD   OE1  OE2                                  
REMARK 470     LYS C 393    CG   CD   CE   NZ                                   
REMARK 470     ASP C 394    CG   OD1  OD2                                       
REMARK 470     ARG C 405    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLN C 432    CG   CD   OE1  NE2                                  
REMARK 470     ASP C 437    CG   OD1  OD2                                       
REMARK 470     GLU C 465    CG   CD   OE1  OE2                                  
REMARK 470     ASP C 503    CG   OD1  OD2                                       
REMARK 470     GLU C 508    CG   CD   OE1  OE2                                  
REMARK 470     LYS C 512    CG   CD   CE   NZ                                   
REMARK 470     ARG C 513    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU C 515    CG   CD1  CD2                                       
REMARK 470     ASP C 532    CG   OD1  OD2                                       
REMARK 470     GLU C 533    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 541    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 555    CG   CD   OE1  OE2                                  
REMARK 470     LYS C 558    CG   CD   CE   NZ                                   
REMARK 470     LYS C 581    CG   CD   CE   NZ                                   
REMARK 470     LYS C 583    CG   CD   CE   NZ                                   
REMARK 470     GLU C 584    CG   CD   OE1  OE2                                  
REMARK 470     ASP C 585    CG   OD1  OD2                                       
REMARK 470     LYS C 587    CG   CD   CE   NZ                                   
REMARK 470     GLN C 588    CG   CD   OE1  NE2                                  
REMARK 470     LYS C 635    CG   CD   CE   NZ                                   
REMARK 470     GLU C 637    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 641    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 649    CG   CD   OE1  OE2                                  
REMARK 470     LYS C 665    CG   CD   CE   NZ                                   
REMARK 470     GLU C 667    CG   CD   OE1  OE2                                  
REMARK 470     ASP C 672    CG   OD1  OD2                                       
REMARK 470     GLU C 679    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 684    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 713    CG   CD   OE1  OE2                                  
REMARK 470     MET C 715    CG   SD   CE                                        
REMARK 470     ASP C 716    CG   OD1  OD2                                       
REMARK 470     LYS C 718    CG   CD   CE   NZ                                   
REMARK 470     ASP C 722    CG   OD1  OD2                                       
REMARK 470     ARG C 745    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS C 746    CG   CD   CE   NZ                                   
REMARK 470     LYS C 749    CG   CD   CE   NZ                                   
REMARK 470     GLU C 754    CG   CD   OE1  OE2                                  
REMARK 470     TRP C 757    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP C 757    CZ3  CH2                                            
REMARK 470     ARG C 763    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     TRP C 766    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP C 766    CZ3  CH2                                            
REMARK 470     VAL C 770    CG1  CG2                                            
REMARK 470     LEU C 779    CG   CD1  CD2                                       
REMARK 470     GLU C 793    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 805    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 810    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 811    CG   CD   OE1  OE2                                  
REMARK 470     LYS C 819    CG   CD   CE   NZ                                   
REMARK 470     LYS C 835    CG   CD   CE   NZ                                   
REMARK 470     GLU C 863    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 877    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 878    CG   CD   OE1  OE2                                  
REMARK 470     LYS C 881    CG   CD   CE   NZ                                   
REMARK 470     LYS C 882    CG   CD   CE   NZ                                   
REMARK 470     ARG C 887    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS C 893    CG   CD   CE   NZ                                   
REMARK 470     GLU C 901    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 910    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 915    CG   CD   OE1  OE2                                  
REMARK 470     MET C 927    CG   SD   CE                                        
REMARK 470     LYS C 935    CG   CD   CE   NZ                                   
REMARK 470     LYS C 947    CG   CD   CE   NZ                                   
REMARK 470     ASP C 948    CG   OD1  OD2                                       
REMARK 470     LYS C 969    CG   CD   CE   NZ                                   
REMARK 470     LYS C 974    CG   CD   CE   NZ                                   
REMARK 470     PHE C 981    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     MET C 982    CG   SD   CE                                        
REMARK 470     SER C 983    OG                                                  
REMARK 470     ASN C 984    CG   OD1  ND2                                       
REMARK 470     PRO C 987    CG   CD                                             
REMARK 470     THR C 988    OG1  CG2                                            
REMARK 470     LEU C 989    CG   CD1  CD2                                       
REMARK 470     GLU C 990    CG   CD   OE1  OE2                                  
REMARK 470     LYS C 991    CG   CD   CE   NZ                                   
REMARK 470     TYR C 992    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ILE C 993    CG1  CG2  CD1                                       
REMARK 470     SER C 994    OG                                                  
REMARK 470     GLU C 996    CG   CD   OE1  OE2                                  
REMARK 470     LEU C 997    CG   CD1  CD2                                       
REMARK 470     LYS H  67    CG   CD   CE   NZ                                   
REMARK 470     GLN H  68    CG   CD   OE1  NE2                                  
REMARK 470     GLU H 410    CG   CD   OE1  OE2                                  
REMARK 470     ASN H 441    CG   OD1  ND2                                       
REMARK 470     LYS H 444    CG   CD   CE   NZ                                   
REMARK 470     LEU H 445    CG   CD1  CD2                                       
REMARK 470     ASP H 446    CG   OD1  OD2                                       
REMARK 470     GLU H 452    CG   CD   OE1  OE2                                  
REMARK 470     ASN K 153    CG   OD1  ND2                                       
REMARK 470     ASP K 154    CG   OD1  OD2                                       
REMARK 470     ARG K 155    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU K 157    CG   CD   OE1  OE2                                  
REMARK 470     ASP K 159    CG   OD1  OD2                                       
REMARK 470     ASP K 191    CG   OD1  OD2                                       
REMARK 470     ARG L   8    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS L  10    CG   CD   CE   NZ                                   
REMARK 470     ASP L  14    CG   OD1  OD2                                       
REMARK 470     GLU L  17    CG   CD   OE1  OE2                                  
REMARK 470     LYS L  18    CG   CD   CE   NZ                                   
REMARK 470     LYS L  20    CG   CD   CE   NZ                                   
REMARK 470     ASP L  25    CG   OD1  OD2                                       
REMARK 470     GLU L  27    CG   CD   OE1  OE2                                  
REMARK 470     GLU L  47    CG   CD   OE1  OE2                                  
REMARK 470     GLU L  51    CG   CD   OE1  OE2                                  
REMARK 470     LYS L  69    CG   CD   CE   NZ                                   
REMARK 470     ARG L  70    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS L  71    CG   CD   CE   NZ                                   
REMARK 470     ASP L  76    CG   OD1  OD2                                       
REMARK 470     ASP L  79    CG   OD1  OD2                                       
REMARK 470     LYS L  83    CG   CD   CE   NZ                                   
REMARK 470     GLU L  84    CG   CD   OE1  OE2                                  
REMARK 470     GLU L 101    CG   CD   OE1  OE2                                  
REMARK 470     GLU L 113    CG   CD   OE1  OE2                                  
REMARK 470     GLN L 128    CG   CD   OE1  NE2                                  
REMARK 470     GLU L 130    CG   CD   OE1  OE2                                  
REMARK 470     GLU L 131    CG   CD   OE1  OE2                                  
REMARK 470     GLU L 132    CG   CD   OE1  OE2                                  
REMARK 470     ARG L 134    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS L 135    CG   CD   CE   NZ                                   
REMARK 470     LYS L 136    CG   CD   CE   NZ                                   
REMARK 470     ARG L 151    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU M 107    CG   CD   OE1  OE2                                  
REMARK 470     GLU M 115    CG   CD   OE1  OE2                                  
REMARK 470     LYS N 198    CG   CD   CE   NZ                                   
REMARK 470     GLU P  26    CG   CD   OE1  OE2                                  
REMARK 470     ASN R  27    CG   OD1  ND2                                       
REMARK 470     ASN R  28    CG   OD1  ND2                                       
REMARK 470     ARG R  29    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG R  30    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLN R  33    CG   CD   OE1  NE2                                  
REMARK 470     SER R  35    OG                                                  
REMARK 470     GLN R  36    CG   CD   OE1  NE2                                  
REMARK 470     GLN R  37    CG   CD   OE1  NE2                                  
REMARK 470     GLN R  38    CG   CD   OE1  NE2                                  
REMARK 470     ARG R  39    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLN R  40    CG   CD   OE1  NE2                                  
REMARK 470     GLN R  41    CG   CD   OE1  NE2                                  
REMARK 470     ARG R  42    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLN R  43    CG   CD   OE1  NE2                                  
REMARK 470     ASN R  44    CG   OD1  ND2                                       
REMARK 470     ILE R  46    CG1  CG2  CD1                                       
REMARK 470     LYS R  47    CG   CD   CE   NZ                                   
REMARK 470     LYS R  48    CG   CD   CE   NZ                                   
REMARK 470     SER R  50    OG                                                  
REMARK 470     LEU R  58    CG   CD1  CD2                                       
REMARK 470     VAL R  60    CG1  CG2                                            
REMARK 470     GLN R  61    CG   CD   OE1  NE2                                  
REMARK 470     LYS R  62    CG   CD   CE   NZ                                   
REMARK 470     GLN R  63    CG   CD   OE1  NE2                                  
REMARK 470     ILE R  64    CG1  CG2  CD1                                       
REMARK 470     GLU R  65    CG   CD   OE1  OE2                                  
REMARK 470     THR R  66    OG1  CG2                                            
REMARK 470     HIS R  67    CG   ND1  CD2  CE1  NE2                             
REMARK 470     MET R  68    CG   SD   CE                                        
REMARK 470     GLU R  69    CG   CD   OE1  OE2                                  
REMARK 470     LYS R  70    CG   CD   CE   NZ                                   
REMARK 470     ARG R  71    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU R  72    CG   CD   OE1  OE2                                  
REMARK 470     ILE R  73    CG1  CG2  CD1                                       
REMARK 470     GLU R  74    CG   CD   OE1  OE2                                  
REMARK 470     VAL R  75    CG1  CG2                                            
REMARK 470     GLN R  76    CG   CD   OE1  NE2                                  
REMARK 470     VAL R  77    CG1  CG2                                            
REMARK 470     SER R  78    OG                                                  
REMARK 470     GLU R  79    CG   CD   OE1  OE2                                  
REMARK 470     LEU R  80    CG   CD1  CD2                                       
REMARK 470     ARG R  81    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP R  82    CG   OD1  OD2                                       
REMARK 470     ARG R  83    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU R  84    CG   CD1  CD2                                       
REMARK 470     GLU R  85    CG   CD   OE1  OE2                                  
REMARK 470     GLU R  86    CG   CD   OE1  OE2                                  
REMARK 470     GLU R  87    CG   CD   OE1  OE2                                  
REMARK 470     GLU R  88    CG   CD   OE1  OE2                                  
REMARK 470     THR R  89    OG1  CG2                                            
REMARK 470     LEU R  90    CG   CD1  CD2                                       
REMARK 470     SER R  91    OG                                                  
REMARK 470     GLU R  93    CG   CD   OE1  OE2                                  
REMARK 470     GLN R  94    CG   CD   OE1  NE2                                  
REMARK 470     ILE R  95    CG1  CG2  CD1                                       
REMARK 470     LYS R  97    CG   CD   CE   NZ                                   
REMARK 470     LYS R  98    CG   CD   CE   NZ                                   
REMARK 470     CYS R  99    SG                                                  
REMARK 470     GLU R 100    CG   CD   OE1  OE2                                  
REMARK 470     LEU R 102    CG   CD1  CD2                                       
REMARK 470     ARG R 103    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS R 105    CG   CD   CE   NZ                                   
REMARK 470     LEU R 106    CG   CD1  CD2                                       
REMARK 470     ASN R 108    CG   OD1  ND2                                       
REMARK 470     GLU R 109    CG   CD   OE1  OE2                                  
REMARK 470     GLN R 111    CG   CD   OE1  NE2                                  
REMARK 470     GLU R 112    CG   CD   OE1  OE2                                  
REMARK 470     GLN R 113    CG   CD   OE1  NE2                                  
REMARK 470     GLN R 114    CG   CD   OE1  NE2                                  
REMARK 470     ARG R 115    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     MET R 116    CG   SD   CE                                        
REMARK 470     GLU S 187    CG   CD   OE1  OE2                                  
REMARK 470     MET S 194    CG   SD   CE                                        
REMARK 470     ASP S 240    CG   OD1  OD2                                       
REMARK 470     ASN S 295    CG   OD1  ND2                                       
REMARK 470     SER S 296    OG                                                  
REMARK 470     ILE S 297    CG1  CG2  CD1                                       
REMARK 470     GLU S 298    CG   CD   OE1  OE2                                  
REMARK 470     GLU S 299    CG   CD   OE1  OE2                                  
REMARK 470     THR S 300    OG1  CG2                                            
REMARK 470     ILE S 301    CG1  CG2  CD1                                       
REMARK 470     SER S 302    OG                                                  
REMARK 470     TYR S 303    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LYS S 304    CG   CD   CE   NZ                                   
REMARK 470     ARG S 305    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS S 306    CG   CD   CE   NZ                                   
REMARK 470     MET S 307    CG   SD   CE                                        
REMARK 470     GLU S 308    CG   CD   OE1  OE2                                  
REMARK 470     TYR S 309    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     GLU S 310    CG   CD   OE1  OE2                                  
REMARK 470     THR S 311    OG1  CG2                                            
REMARK 470     ILE S 312    CG1  CG2  CD1                                       
REMARK 470     LEU S 313    CG   CD1  CD2                                       
REMARK 470     SER S 314    OG                                                  
REMARK 470     ASN S 315    CG   OD1  ND2                                       
REMARK 470     TYR S 320    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ASP S 321    CG   OD1  OD2                                       
REMARK 470     THR S 322    OG1  CG2                                            
REMARK 470     TRP S 323    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP S 323    CZ3  CH2                                            
REMARK 470     TRP S 324    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP S 324    CZ3  CH2                                            
REMARK 470     LEU S 325    CG   CD1  CD2                                       
REMARK 470     TYR S 326    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LEU S 327    CG   CD1  CD2                                       
REMARK 470     ASP S 328    CG   OD1  OD2                                       
REMARK 470     LEU S 329    CG   CD1  CD2                                       
REMARK 470     ILE S 330    CG1  CG2  CD1                                       
REMARK 470     SER S 331    OG                                                  
REMARK 470     GLU S 332    CG   CD   OE1  OE2                                  
REMARK 470     PHE S 334    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     PRO S 335    CG   CD                                             
REMARK 470     LYS S 336    CG   CD   CE   NZ                                   
REMARK 470     GLN S 337    CG   CD   OE1  NE2                                  
REMARK 470     ILE S 338    CG1  CG2  CD1                                       
REMARK 470     MET S 339    CG   SD   CE                                        
REMARK 470     GLN S 340    CG   CD   OE1  NE2                                  
REMARK 470     THR S 341    OG1  CG2                                            
REMARK 470     PHE S 342    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLU S 343    CG   CD   OE1  OE2                                  
REMARK 470     LYS S 344    CG   CD   CE   NZ                                   
REMARK 470     ILE S 346    CG1  CG2  CD1                                       
REMARK 470     VAL S 347    CG1  CG2                                            
REMARK 470     ASP S 348    CG   OD1  OD2                                       
REMARK 470     SER S 349    OG                                                  
REMARK 470     LYS S 356    CG   CD   CE   NZ                                   
REMARK 470     ASN S 357    CG   OD1  ND2                                       
REMARK 470     VAL S 358    CG1  CG2                                            
REMARK 470     GLN S 359    CG   CD   OE1  NE2                                  
REMARK 470     TRP S 360    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP S 360    CZ3  CH2                                            
REMARK 470     LYS S 361    CG   CD   CE   NZ                                   
REMARK 470     ARG S 362    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     TYR S 363    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ILE S 364    CG1  CG2  CD1                                       
REMARK 470     TYR S 365    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LEU S 366    CG   CD1  CD2                                       
REMARK 470     TRP S 367    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP S 367    CZ3  CH2                                            
REMARK 470     MET S 368    CG   SD   CE                                        
REMARK 470     ARG S 369    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     TYR S 370    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ILE S 371    CG1  CG2  CD1                                       
REMARK 470     CYS S 372    SG                                                  
REMARK 470     TYR S 373    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     VAL S 374    CG1  CG2                                            
REMARK 470     GLU S 375    CG   CD   OE1  OE2                                  
REMARK 470     LEU S 376    CG   CD1  CD2                                       
REMARK 470     GLU S 377    CG   CD   OE1  OE2                                  
REMARK 470     SER S 381    OG                                                  
REMARK 470     LEU S 382    CG   CD1  CD2                                       
REMARK 470     LEU S 383    CG   CD1  CD2                                       
REMARK 470     GLU S 384    CG   CD   OE1  OE2                                  
REMARK 470     GLU S 385    CG   CD   OE1  OE2                                  
REMARK 470     GLU S 386    CG   CD   OE1  OE2                                  
REMARK 470     LEU S 387    CG   CD1  CD2                                       
REMARK 470     PHE S 388    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLN S 389    CG   CD   OE1  NE2                                  
REMARK 470     ARG S 390    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU S 391    CG   CD1  CD2                                       
REMARK 470     ILE S 392    CG1  CG2  CD1                                       
REMARK 470     ASP S 393    CG   OD1  OD2                                       
REMARK 470     ASP S 394    CG   OD1  OD2                                       
REMARK 470     ILE S 395    CG1  CG2  CD1                                       
REMARK 470     PHE S 403    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     SER S 404    OG                                                  
REMARK 470     LYS S 405    CG   CD   CE   NZ                                   
REMARK 470     ILE S 406    CG1  CG2  CD1                                       
REMARK 470     TRP S 407    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP S 407    CZ3  CH2                                            
REMARK 470     LEU S 408    CG   CD1  CD2                                       
REMARK 470     MET S 409    CG   SD   CE                                        
REMARK 470     TYR S 410    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LYS S 412    CG   CD   CE   NZ                                   
REMARK 470     PHE S 413    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     LEU S 414    CG   CD1  CD2                                       
REMARK 470     ILE S 415    CG1  CG2  CD1                                       
REMARK 470     ARG S 416    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP S 419    CG   OD1  OD2                                       
REMARK 470     VAL S 420    CG1  CG2                                            
REMARK 470     PRO S 421    CG   CD                                             
REMARK 470     LYS S 422    CG   CD   CE   NZ                                   
REMARK 470     ARG S 424    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS S 425    CG   CD   CE   NZ                                   
REMARK 470     ILE S 426    CG1  CG2  CD1                                       
REMARK 470     LEU S 427    CG   CD1  CD2                                       
REMARK 470     LYS S 429    CG   CD   CE   NZ                                   
REMARK 470     ILE S 431    CG1  CG2  CD1                                       
REMARK 470     THR S 439    OG1  CG2                                            
REMARK 470     PHE S 440    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     LYS S 441    CG   CD   CE   NZ                                   
REMARK 470     TYR S 443    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ILE S 444    CG1  CG2  CD1                                       
REMARK 470     GLU S 445    CG   CD   OE1  OE2                                  
REMARK 470     LEU S 446    CG   CD1  CD2                                       
REMARK 470     GLU S 447    CG   CD   OE1  OE2                                  
REMARK 470     VAL S 448    CG1  CG2                                            
REMARK 470     LYS S 449    CG   CD   CE   NZ                                   
REMARK 470     LEU S 450    CG   CD1  CD2                                       
REMARK 470     GLU S 452    CG   CD   OE1  OE2                                  
REMARK 470     PHE S 453    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASP S 454    CG   OD1  OD2                                       
REMARK 470     ARG S 455    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     VAL S 456    CG1  CG2                                            
REMARK 470     ARG S 457    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS S 458    CG   CD   CE   NZ                                   
REMARK 470     ILE S 459    CG1  CG2  CD1                                       
REMARK 470     TYR S 460    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     GLU S 461    CG   CD   OE1  OE2                                  
REMARK 470     LYS S 462    CG   CD   CE   NZ                                   
REMARK 470     PHE S 463    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ILE S 464    CG1  CG2  CD1                                       
REMARK 470     GLU S 465    CG   CD   OE1  OE2                                  
REMARK 470     PHE S 466    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLN S 467    CG   CD   OE1  NE2                                  
REMARK 470     ASP S 470    CG   OD1  OD2                                       
REMARK 470     LEU S 471    CG   CD1  CD2                                       
REMARK 470     GLN S 472    CG   CD   OE1  NE2                                  
REMARK 470     ILE S 473    CG1  CG2  CD1                                       
REMARK 470     TRP S 474    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP S 474    CZ3  CH2                                            
REMARK 470     SER S 475    OG                                                  
REMARK 470     GLN S 476    CG   CD   OE1  NE2                                  
REMARK 470     TYR S 477    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     GLU S 479    CG   CD   OE1  OE2                                  
REMARK 470     LEU S 480    CG   CD1  CD2                                       
REMARK 470     GLU S 481    CG   CD   OE1  OE2                                  
REMARK 470     GLU S 482    CG   CD   OE1  OE2                                  
REMARK 470     ASN S 483    CG   OD1  ND2                                       
REMARK 470     ASP S 486    CG   OD1  OD2                                       
REMARK 470     TRP S 487    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP S 487    CZ3  CH2                                            
REMARK 470     ASP S 488    CG   OD1  OD2                                       
REMARK 470     ARG S 489    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     VAL S 490    CG1  CG2                                            
REMARK 470     ARG S 491    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ILE S 493    CG1  CG2  CD1                                       
REMARK 470     TYR S 494    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     THR S 495    OG1  CG2                                            
REMARK 470     ILE S 496    CG1  CG2  CD1                                       
REMARK 470     LEU S 498    CG   CD1  CD2                                       
REMARK 470     ASP S 499    CG   OD1  OD2                                       
REMARK 470     GLU S 500    CG   CD   OE1  OE2                                  
REMARK 470     LYS S 507    CG   CD   CE   NZ                                   
REMARK 470     GLU S 508    CG   CD   OE1  OE2                                  
REMARK 470     LYS S 510    CG   CD   CE   NZ                                   
REMARK 470     ILE S 511    CG1  CG2  CD1                                       
REMARK 470     VAL S 512    CG1  CG2                                            
REMARK 470     LEU S 513    CG   CD1  CD2                                       
REMARK 470     LEU S 514    CG   CD1  CD2                                       
REMARK 470     GLN S 515    CG   CD   OE1  NE2                                  
REMARK 470     LYS S 516    CG   CD   CE   NZ                                   
REMARK 470     TYR S 517    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ILE S 518    CG1  CG2  CD1                                       
REMARK 470     THR S 519    OG1  CG2                                            
REMARK 470     PHE S 520    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLU S 521    CG   CD   OE1  OE2                                  
REMARK 470     ARG S 531    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS S 532    CG   CD   CE   NZ                                   
REMARK 470     LEU S 533    CG   CD1  CD2                                       
REMARK 470     TYR S 534    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ARG S 535    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG S 536    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     TYR S 537    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LEU S 538    CG   CD1  CD2                                       
REMARK 470     GLU S 539    CG   CD   OE1  OE2                                  
REMARK 470     LEU S 540    CG   CD1  CD2                                       
REMARK 470     ASN S 541    CG   OD1  ND2                                       
REMARK 470     PRO S 545    CG   CD                                             
REMARK 470     GLN S 546    CG   CD   OE1  NE2                                  
REMARK 470     SER S 547    OG                                                  
REMARK 470     TRP S 548    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP S 548    CZ3  CH2                                            
REMARK 470     ILE S 549    CG1  CG2  CD1                                       
REMARK 470     GLU S 550    CG   CD   OE1  OE2                                  
REMARK 470     PHE S 551    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     MET S 553    CG   SD   CE                                        
REMARK 470     TYR S 554    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     GLN S 555    CG   CD   OE1  NE2                                  
REMARK 470     THR S 556    OG1  CG2                                            
REMARK 470     LEU T 407    CG   CD1  CD2                                       
REMARK 470     VAL T 408    CG1  CG2                                            
REMARK 470     GLU T 409    CG   CD   OE1  OE2                                  
REMARK 470     THR T 410    OG1  CG2                                            
REMARK 470     TRP T 411    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP T 411    CZ3  CH2                                            
REMARK 470     MET T 412    CG   SD   CE                                        
REMARK 470     LYS T 413    CG   CD   CE   NZ                                   
REMARK 470     ARG T 414    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     VAL T 415    CG1  CG2                                            
REMARK 470     SER T 416    OG                                                  
REMARK 470     LEU T 417    CG   CD1  CD2                                       
REMARK 470     GLN T 418    CG   CD   OE1  NE2                                  
REMARK 470     LYS T 419    CG   CD   CE   NZ                                   
REMARK 470     SER T 420    OG                                                  
REMARK 470     GLU T 423    CG   CD   OE1  OE2                                  
REMARK 470     LYS T 424    CG   CD   CE   NZ                                   
REMARK 470     CYS T 425    SG                                                  
REMARK 470     ASN T 426    CG   OD1  ND2                                       
REMARK 470     VAL T 427    CG1  CG2                                            
REMARK 470     TYR T 428    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     SER T 429    OG                                                  
REMARK 470     GLU T 430    CG   CD   OE1  OE2                                  
REMARK 470     ILE T 432    CG1  CG2  CD1                                       
REMARK 470     LEU T 433    CG   CD1  CD2                                       
REMARK 470     LYS T 434    CG   CD   CE   NZ                                   
REMARK 470     ILE T 435    CG1  CG2  CD1                                       
REMARK 470     ASP T 436    CG   OD1  OD2                                       
REMARK 470     PRO T 437    CG   CD                                             
REMARK 470     ARG T 438    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS T 439    CG   CD   CE   NZ                                   
REMARK 470     VAL T 440    CG1  CG2                                            
REMARK 470     THR T 442    OG1  CG2                                            
REMARK 470     PRO T 443    CG   CD                                             
REMARK 470     SER T 445    OG                                                  
REMARK 470     PHE T 446    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ARG T 448    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU T 449    CG   CD1  CD2                                       
REMARK 470     TRP T 450    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP T 450    CZ3  CH2                                            
REMARK 470     CYS T 451    SG                                                  
REMARK 470     SER T 452    OG                                                  
REMARK 470     TYR T 453    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ASP T 455    CG   OD1  OD2                                       
REMARK 470     LEU T 456    CG   CD1  CD2                                       
REMARK 470     TYR T 457    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     TRP T 458    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP T 458    CZ3  CH2                                            
REMARK 470     ARG T 459    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     SER T 460    OG                                                  
REMARK 470     ASN T 461    CG   OD1  ND2                                       
REMARK 470     ILE T 463    CG1  CG2  CD1                                       
REMARK 470     SER T 464    OG                                                  
REMARK 470     THR T 465    OG1  CG2                                            
REMARK 470     ARG T 467    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU T 468    CG   CD   OE1  OE2                                  
REMARK 470     LEU T 469    CG   CD1  CD2                                       
REMARK 470     TRP T 470    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP T 470    CZ3  CH2                                            
REMARK 470     THR T 471    OG1  CG2                                            
REMARK 470     GLN T 472    CG   CD   OE1  NE2                                  
REMARK 470     SER T 473    OG                                                  
REMARK 470     LEU T 474    CG   CD1  CD2                                       
REMARK 470     LYS T 475    CG   CD   CE   NZ                                   
REMARK 470     VAL T 476    CG1  CG2                                            
REMARK 470     PRO T 477    CG   CD                                             
REMARK 470     TYR T 478    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     PRO T 479    CG   CD                                             
REMARK 470     TYR T 480    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ILE T 481    CG1  CG2  CD1                                       
REMARK 470     GLU T 482    CG   CD   OE1  OE2                                  
REMARK 470     ASP T 483    CG   OD1  OD2                                       
REMARK 470     LEU T 484    CG   CD1  CD2                                       
REMARK 470     GLU T 485    CG   CD   OE1  OE2                                  
REMARK 470     GLU T 486    CG   CD   OE1  OE2                                  
REMARK 470     ILE T 487    CG1  CG2  CD1                                       
REMARK 470     TYR T 488    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LEU T 489    CG   CD1  CD2                                       
REMARK 470     ASN T 490    CG   OD1  ND2                                       
REMARK 470     TRP T 491    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP T 491    CZ3  CH2                                            
REMARK 470     ASP T 493    CG   OD1  OD2                                       
REMARK 470     ARG T 494    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU T 495    CG   CD   OE1  OE2                                  
REMARK 470     LEU T 496    CG   CD1  CD2                                       
REMARK 470     ASP T 497    CG   OD1  OD2                                       
REMARK 470     VAL T 501    CG1  CG2                                            
REMARK 470     GLU T 502    CG   CD   OE1  OE2                                  
REMARK 470     ARG T 503    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     PHE T 505    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     SER T 506    OG                                                  
REMARK 470     ILE T 507    CG1  CG2  CD1                                       
REMARK 470     LEU T 508    CG   CD1  CD2                                       
REMARK 470     GLU T 509    CG   CD   OE1  OE2                                  
REMARK 470     ASP T 510    CG   OD1  OD2                                       
REMARK 470     LEU T 512    CG   CD1  CD2                                       
REMARK 470     HIS T 513    CG   ND1  CD2  CE1  NE2                             
REMARK 470     VAL T 514    CG1  CG2                                            
REMARK 470     PRO T 515    CG   CD                                             
REMARK 470     THR T 516    OG1  CG2                                            
REMARK 470     ASN T 517    CG   OD1  ND2                                       
REMARK 470     PRO T 518    CG   CD                                             
REMARK 470     GLU T 519    CG   CD   OE1  OE2                                  
REMARK 470     ILE T 520    CG1  CG2  CD1                                       
REMARK 470     LEU T 521    CG   CD1  CD2                                       
REMARK 470     LEU T 522    CG   CD1  CD2                                       
REMARK 470     GLU T 523    CG   CD   OE1  OE2                                  
REMARK 470     SER T 541    OG                                                  
REMARK 470     LEU T 542    CG   CD1  CD2                                       
REMARK 470     ARG T 543    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ILE T 544    CG1  CG2  CD1                                       
REMARK 470     TRP T 545    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP T 545    CZ3  CH2                                            
REMARK 470     SER T 546    OG                                                  
REMARK 470     LYS T 547    CG   CD   CE   NZ                                   
REMARK 470     TYR T 548    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ILE T 549    CG1  CG2  CD1                                       
REMARK 470     ASP T 550    CG   OD1  OD2                                       
REMARK 470     TYR T 551    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LEU T 552    CG   CD1  CD2                                       
REMARK 470     GLU T 553    CG   CD   OE1  OE2                                  
REMARK 470     TYR T 555    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ILE T 566    CG1  CG2  CD1                                       
REMARK 470     PHE T 567    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASN T 568    CG   OD1  ND2                                       
REMARK 470     LYS T 569    CG   CD   CE   NZ                                   
REMARK 470     THR T 570    OG1  CG2                                            
REMARK 470     LYS T 571    CG   CD   CE   NZ                                   
REMARK 470     MET T 572    CG   SD   CE                                        
REMARK 470     TYR T 574    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ASN T 575    CG   OD1  ND2                                       
REMARK 470     THR T 576    OG1  CG2                                            
REMARK 470     VAL T 577    CG1  CG2                                            
REMARK 470     ILE T 578    CG1  CG2  CD1                                       
REMARK 470     ASP T 579    CG   OD1  OD2                                       
REMARK 470     LEU T 580    CG   CD1  CD2                                       
REMARK 470     ARG T 581    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     PRO T 585    CG   CD                                             
REMARK 470     MET T 587    CG   SD   CE                                        
REMARK 470     GLU T 589    CG   CD   OE1  OE2                                  
REMARK 470     ASN T 590    CG   OD1  ND2                                       
REMARK 470     PHE T 591    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     LEU T 593    CG   CD1  CD2                                       
REMARK 470     PHE T 594    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     LEU T 595    CG   CD1  CD2                                       
REMARK 470     GLN T 596    CG   CD   OE1  NE2                                  
REMARK 470     ASN T 597    CG   OD1  ND2                                       
REMARK 470     HIS T 598    CG   ND1  CD2  CE1  NE2                             
REMARK 470     VAL T 601    CG1  CG2                                            
REMARK 470     MET T 602    CG   SD   CE                                        
REMARK 470     GLU T 603    CG   CD   OE1  OE2                                  
REMARK 470     SER T 604    OG                                                  
REMARK 470     PHE T 605    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLN T 606    CG   CD   OE1  NE2                                  
REMARK 470     VAL T 607    CG1  CG2                                            
REMARK 470     TYR T 608    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     GLU T 609    CG   CD   OE1  OE2                                  
REMARK 470     LYS T 610    CG   CD   CE   NZ                                   
REMARK 470     THR T 611    OG1  CG2                                            
REMARK 470     ILE T 612    CG1  CG2  CD1                                       
REMARK 470     PRO T 613    CG   CD                                             
REMARK 470     LEU T 614    CG   CD1  CD2                                       
REMARK 470     PHE T 615    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     PRO T 616    CG   CD                                             
REMARK 470     GLU T 618    CG   CD   OE1  OE2                                  
REMARK 470     ILE T 619    CG1  CG2  CD1                                       
REMARK 470     GLN T 620    CG   CD   OE1  NE2                                  
REMARK 470     TYR T 621    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     GLU T 622    CG   CD   OE1  OE2                                  
REMARK 470     LEU T 623    CG   CD1  CD2                                       
REMARK 470     TRP T 624    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP T 624    CZ3  CH2                                            
REMARK 470     ILE T 625    CG1  CG2  CD1                                       
REMARK 470     GLU T 626    CG   CD   OE1  OE2                                  
REMARK 470     TYR T 627    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LEU T 628    CG   CD1  CD2                                       
REMARK 470     GLU T 629    CG   CD   OE1  OE2                                  
REMARK 470     VAL T 630    CG1  CG2                                            
REMARK 470     THR T 632    OG1  CG2                                            
REMARK 470     SER T 633    OG                                                  
REMARK 470     HIS T 634    CG   ND1  CD2  CE1  NE2                             
REMARK 470     PRO T 641    CG   CD                                             
REMARK 470     GLU T 642    CG   CD   OE1  OE2                                  
REMARK 470     HIS T 643    CG   ND1  CD2  CE1  NE2                             
REMARK 470     ILE T 644    CG1  CG2  CD1                                       
REMARK 470     ARG T 645    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     PHE T 646    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     LEU T 647    CG   CD1  CD2                                       
REMARK 470     PHE T 648    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLU T 649    CG   CD   OE1  OE2                                  
REMARK 470     LYS T 650    CG   CD   CE   NZ                                   
REMARK 470     LEU T 652    CG   CD1  CD2                                       
REMARK 470     LYS T 653    CG   CD   CE   NZ                                   
REMARK 470     ASN T 654    CG   OD1  ND2                                       
REMARK 470     LEU T 655    CG   CD1  CD2                                       
REMARK 470     CYS T 656    SG                                                  
REMARK 470     SER T 657    OG                                                  
REMARK 470     ASN T 658    CG   OD1  ND2                                       
REMARK 470     ILE T 660    CG1  CG2  CD1                                       
REMARK 470     ASP T 661    CG   OD1  OD2                                       
REMARK 470     CYS T 662    SG                                                  
REMARK 470     LYS T 663    CG   CD   CE   NZ                                   
REMARK 470     THR T 664    OG1  CG2                                            
REMARK 470     ILE T 665    CG1  CG2  CD1                                       
REMARK 470     PHE T 666    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ILE T 667    CG1  CG2  CD1                                       
REMARK 470     TYR T 669    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     SER T 670    OG                                                  
REMARK 470     VAL T 671    CG1  CG2                                            
REMARK 470     PHE T 672    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLU T 673    CG   CD   OE1  OE2                                  
REMARK 470     GLU T 674    CG   CD   OE1  OE2                                  
REMARK 470     ARG T 675    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ILE T 676    CG1  CG2  CD1                                       
REMARK 470     SER T 677    OG                                                  
REMARK 470     ILE T 680    CG1  CG2  CD1                                       
REMARK 470     SER T 681    OG                                                  
REMARK 470     LYS T 682    CG   CD   CE   NZ                                   
REMARK 470     SER T 683    OG                                                  
REMARK 470     ILE T 684    CG1  CG2  CD1                                       
REMARK 470     GLU T 685    CG   CD   OE1  OE2                                  
REMARK 470     ILE T 686    CG1  CG2  CD1                                       
REMARK 470     LEU T 687    CG   CD1  CD2                                       
REMARK 470     ARG T 688    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG T 689    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     VAL T 692    CG1  CG2                                            
REMARK 470     ILE T 693    CG1  CG2  CD1                                       
REMARK 470     LEU T 702    CG   CD1  CD2                                       
REMARK 470     GLU T 703    CG   CD   OE1  OE2                                  
REMARK 470     SER T 704    OG                                                  
REMARK 470     ARG T 705    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU T 706    CG   CD1  CD2                                       
REMARK 470     GLN T 707    CG   CD   OE1  NE2                                  
REMARK 470     LEU T 708    CG   CD1  CD2                                       
REMARK 470     TRP T 709    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP T 709    CZ3  CH2                                            
REMARK 470     ARG T 710    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     MET T 711    CG   SD   CE                                        
REMARK 470     CYS T 712    SG                                                  
REMARK 470     ILE T 713    CG1  CG2  CD1                                       
REMARK 470     SER T 714    OG                                                  
REMARK 470     LYS T 715    CG   CD   CE   NZ                                   
REMARK 470     GLU T 717    CG   CD   OE1  OE2                                  
REMARK 470     SER T 718    OG                                                  
REMARK 470     THR T 719    OG1  CG2                                            
REMARK 470     SER T 723    OG                                                  
REMARK 470     VAL T 724    CG1  CG2                                            
REMARK 470     THR T 725    OG1  CG2                                            
REMARK 470     ARG T 726    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU T 727    CG   CD   OE1  OE2                                  
REMARK 470     LEU T 728    CG   CD1  CD2                                       
REMARK 470     TYR T 729    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     GLN T 730    CG   CD   OE1  NE2                                  
REMARK 470     GLU T 731    CG   CD   OE1  OE2                                  
REMARK 470     CYS T 732    SG                                                  
REMARK 470     ILE T 733    CG1  CG2  CD1                                       
REMARK 470     GLN T 734    CG   CD   OE1  NE2                                  
REMARK 470     ILE T 735    CG1  CG2  CD1                                       
REMARK 470     SER T 739    OG                                                  
REMARK 470     LYS T 740    CG   CD   CE   NZ                                   
REMARK 470     VAL T 742    CG1  CG2                                            
REMARK 470     GLU T 743    CG   CD   OE1  OE2                                  
REMARK 470     PHE T 744    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     VAL T 745    CG1  CG2                                            
REMARK 470     ILE T 746    CG1  CG2  CD1                                       
REMARK 470     LYS T 747    CG   CD   CE   NZ                                   
REMARK 470     PHE T 748    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     SER T 749    OG                                                  
REMARK 470     ASP T 750    CG   OD1  OD2                                       
REMARK 470     PHE T 751    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLU T 752    CG   CD   OE1  OE2                                  
REMARK 470     SER T 753    OG                                                  
REMARK 470     SER T 754    OG                                                  
REMARK 470     ILE T 755    CG1  CG2  CD1                                       
REMARK 470     THR T 758    OG1  CG2                                            
REMARK 470     ILE T 759    CG1  CG2  CD1                                       
REMARK 470     ARG T 760    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG T 762    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU T 763    CG   CD   OE1  OE2                                  
REMARK 470     ILE T 764    CG1  CG2  CD1                                       
REMARK 470     LEU T 765    CG   CD1  CD2                                       
REMARK 470     TYR T 767    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LYS T 770    CG   CD   CE   NZ                                   
REMARK 470     LEU T 771    CG   CD1  CD2                                       
REMARK 470     ASN T 777    CG   OD1  ND2                                       
REMARK 470     THR T 778    OG1  CG2                                            
REMARK 470     GLU T 779    CG   CD   OE1  OE2                                  
REMARK 470     LEU T 780    CG   CD1  CD2                                       
REMARK 470     TRP T 781    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP T 781    CZ3  CH2                                            
REMARK 470     ASP T 782    CG   OD1  OD2                                       
REMARK 470     SER T 783    OG                                                  
REMARK 470     PHE T 784    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLU T 785    CG   CD   OE1  OE2                                  
REMARK 470     ILE T 786    CG1  CG2  CD1                                       
REMARK 470     PHE T 787    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLU T 788    CG   CD   OE1  OE2                                  
REMARK 470     LEU T 789    CG   CD1  CD2                                       
REMARK 470     LYS T 790    CG   CD   CE   NZ                                   
REMARK 470     GLU a 134    CG   CD   OE1  OE2                                  
REMARK 470     GLU a 175    CG   CD   OE1  OE2                                  
REMARK 470     GLU a 241    CG   CD   OE1  OE2                                  
REMARK 470     ASP c 166    CG   OD1  OD2                                       
REMARK 470     ASP c 168    CG   OD1  OD2                                       
REMARK 470     LYS c 171    CG   CD   CE   NZ                                   
REMARK 470     ASP c 172    CG   OD1  OD2                                       
REMARK 470     LYS c 180    CG   CD   CE   NZ                                   
REMARK 470     GLU c 184    CG   CD   OE1  OE2                                  
REMARK 470     LYS c 188    CG   CD   CE   NZ                                   
REMARK 470     LYS c 196    CG   CD   CE   NZ                                   
REMARK 470     GLU c 215    CG   CD   OE1  OE2                                  
REMARK 470     GLU c 222    CG   CD   OE1  OE2                                  
REMARK 470     ASP c 226    CG   OD1  OD2                                       
REMARK 470     GLU c 295    CG   CD   OE1  OE2                                  
REMARK 470     ARG c 307    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS c 311    CG   CD   CE   NZ                                   
REMARK 470     ASP c 317    CG   OD1  OD2                                       
REMARK 470     GLU c 318    CG   CD   OE1  OE2                                  
REMARK 470     GLU c 320    CG   CD   OE1  OE2                                  
REMARK 470     ASP c 321    CG   OD1  OD2                                       
REMARK 470     LYS c 322    CG   CD   CE   NZ                                   
REMARK 470     GLU c 323    CG   CD   OE1  OE2                                  
REMARK 470     LYS c 324    CG   CD   CE   NZ                                   
REMARK 470     HIS c 327    CG   ND1  CD2  CE1  NE2                             
REMARK 470     GLU c 337    CG   CD   OE1  OE2                                  
REMARK 470     GLU o 197    CG   CD   OE1  OE2                                  
REMARK 470     ARG o 228    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS o 307    CG   CD   CE   NZ                                   
REMARK 470     GLU o 313    CG   CD   OE1  OE2                                  
REMARK 470     LYS o 315    CG   CD   CE   NZ                                   
REMARK 470     ARG o 318    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU o 321    CG   CD   OE1  OE2                                  
REMARK 470     ASN o 358    CG   OD1  ND2                                       
REMARK 470     LEU o 365    CG   CD1  CD2                                       
REMARK 470     LYS o 366    CG   CD   CE   NZ                                   
REMARK 470     LYS o 368    CG   CD   CE   NZ                                   
REMARK 470     TYR o 369    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LYS o 370    CG   CD   CE   NZ                                   
REMARK 470     ARG o 371    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     HIS o 372    CG   ND1  CD2  CE1  NE2                             
REMARK 470     LYS o 374    CG   CD   CE   NZ                                   
REMARK 470     LYS o 375    CG   CD   CE   NZ                                   
REMARK 470     LYS o 378    CG   CD   CE   NZ                                   
REMARK 470     HIS o 380    CG   ND1  CD2  CE1  NE2                             
REMARK 470     LYS o 404    CG   CD   CE   NZ                                   
REMARK 470     ASN o 422    CG   OD1  ND2                                       
REMARK 470     LYS o 423    CG   CD   CE   NZ                                   
REMARK 470     PRO o 428    CG   CD                                             
REMARK 470     ILE o 429    CG1  CG2  CD1                                       
REMARK 470     THR o 430    OG1  CG2                                            
REMARK 470     ASP o 433    CG   OD1  OD2                                       
REMARK 470     GLN o 437    CG   CD   OE1  NE2                                  
REMARK 470     GLU o 438    CG   CD   OE1  OE2                                  
REMARK 470     LYS o 441    CG   CD   CE   NZ                                   
REMARK 470     LYS b  55    CG   CD   CE   NZ                                   
REMARK 470     GLU b  98    CG   CD   OE1  OE2                                  
REMARK 470     ASP b  99    CG   OD1  OD2                                       
REMARK 470     GLU d  13    CG   CD   OE1  OE2                                  
REMARK 470     ASP d  46    CG   OD1  OD2                                       
REMARK 470     GLU e  56    CG   CD   OE1  OE2                                  
REMARK 470     GLU e  59    CG   CD   OE1  OE2                                  
REMARK 470     LYS e  73    CG   CD   CE   NZ                                   
REMARK 470     GLU f  37    CG   CD   OE1  OE2                                  
REMARK 470     GLU g   6    CG   CD   OE1  OE2                                  
REMARK 470     ASP g  42    CG   OD1  OD2                                       
REMARK 470     GLU j  19    CG   CD   OE1  OE2                                  
REMARK 470     GLU j  20    CG   CD   OE1  OE2                                  
REMARK 470     GLU j  22    CG   CD   OE1  OE2                                  
REMARK 470     GLU j  23    CG   CD   OE1  OE2                                  
REMARK 470     GLU j  25    CG   CD   OE1  OE2                                  
REMARK 470     ASP j  36    CG   OD1  OD2                                       
REMARK 470     GLU j  74    CG   CD   OE1  OE2                                  
REMARK 470     GLU j  88    CG   CD   OE1  OE2                                  
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT                     
REMARK 500                                                                      
REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT.                            
REMARK 500                                                                      
REMARK 500  ATM1  RES C  SSEQI   ATM2  RES C  SSEQI           DISTANCE          
REMARK 500   O    LYS H   311     CD2  LEU H   315              1.85            
REMARK 500   OP1    A 6    79     O2'    G 6    81              2.12            
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: COVALENT BOND LENGTHS                                      
REMARK 500                                                                      
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES              
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE               
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                 
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT: (10X,I3,1X,2(A3,1X,A1,I4,A1,1X,A4,3X),1X,F6.3)               
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999                        
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996                     
REMARK 500                                                                      
REMARK 500  M RES CSSEQI ATM1   RES CSSEQI ATM2   DEVIATION                     
REMARK 500    SER c 230   C     SER c 230   O       0.116                       
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES                                       
REMARK 500                                                                      
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES              
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE               
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                 
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)              
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999                        
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996                     
REMARK 500                                                                      
REMARK 500  M RES CSSEQI ATM1   ATM2   ATM3                                     
REMARK 500      A 6  45   C2' -  C3' -  O3' ANGL. DEV. =  11.5 DEGREES          
REMARK 500    PRO C 987   C   -  N   -  CA  ANGL. DEV. =  10.6 DEGREES          
REMARK 500    PRO J 195   C   -  N   -  CA  ANGL. DEV. =   9.0 DEGREES          
REMARK 500    CYS N  16   CA  -  CB  -  SG  ANGL. DEV. =   8.8 DEGREES          
REMARK 500    PRO T 613   C   -  N   -  CA  ANGL. DEV. =  13.4 DEGREES          
REMARK 500    PRO T 616   C   -  N   -  CA  ANGL. DEV. =  11.3 DEGREES          
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: TORSION ANGLES                                             
REMARK 500                                                                      
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:            
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)                    
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-           
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400            
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        PSI       PHI                                   
REMARK 500    GLU A 133       91.09    -65.90                                   
REMARK 500    HIS A 146       37.79    -89.50                                   
REMARK 500    ALA A 150       32.66   -155.78                                   
REMARK 500    ASN A 178       36.25    -98.04                                   
REMARK 500    GLN A 271      -66.82   -127.04                                   
REMARK 500    ASP A 273       45.17    -94.79                                   
REMARK 500    GLU A 288     -114.18    -92.30                                   
REMARK 500    TYR A 298       62.67     65.96                                   
REMARK 500    SER A 302       80.53   -161.29                                   
REMARK 500    THR A 316      -39.85    -38.98                                   
REMARK 500    VAL A 322       98.05   -160.76                                   
REMARK 500    ASP A 324       88.79    -66.56                                   
REMARK 500    TYR A 328       44.21    -77.43                                   
REMARK 500    PHE A 331       21.09   -151.64                                   
REMARK 500    PHE A 387       76.25   -115.93                                   
REMARK 500    ASN A 413      -72.52    -76.75                                   
REMARK 500    ASP A 418       82.89     44.56                                   
REMARK 500    ASP A 457       79.45     62.09                                   
REMARK 500    PHE A 484      -39.62    -37.30                                   
REMARK 500    ASN A 487      -46.85    -19.67                                   
REMARK 500    ASP A 511      -77.99    -53.43                                   
REMARK 500    GLU A 512      112.68   -160.23                                   
REMARK 500    ASN A 596       21.71    -79.09                                   
REMARK 500    ARG A 614       88.40    -68.92                                   
REMARK 500    THR A 664      113.05   -163.63                                   
REMARK 500    PHE A 703       85.32     56.47                                   
REMARK 500    PHE A 734      -75.44    -80.64                                   
REMARK 500    GLU A 740       62.78   -101.42                                   
REMARK 500    VAL A 742      115.48     -0.23                                   
REMARK 500    PRO A 986      -38.89    -37.83                                   
REMARK 500    ARG A1043       46.47    -89.20                                   
REMARK 500    LYS A1093       73.94     27.52                                   
REMARK 500    LEU A1165       72.64     57.40                                   
REMARK 500    GLU A1196      -67.39     61.89                                   
REMARK 500    ILE A1241       76.90   -105.08                                   
REMARK 500    VAL A1278       96.85    -68.91                                   
REMARK 500    SER A1280      103.51    -58.62                                   
REMARK 500    ASN A1281      117.47    -36.62                                   
REMARK 500    ASP A1282     -167.53    -74.64                                   
REMARK 500    SER A1377      -72.41    -97.97                                   
REMARK 500    SER A1403      -60.45   -129.41                                   
REMARK 500    ILE A1405      138.02    -30.85                                   
REMARK 500    ASP A1411      100.57    -59.35                                   
REMARK 500    ASP A1498       69.43   -160.03                                   
REMARK 500    PHE A1525       40.55   -102.83                                   
REMARK 500    ASN A1538      107.00   -160.14                                   
REMARK 500    LEU A1550       43.76    -96.39                                   
REMARK 500    TYR A1620     -129.88    -61.59                                   
REMARK 500    ILE A1632       77.33   -105.78                                   
REMARK 500    PHE A1649       53.20   -104.23                                   
REMARK 500                                                                      
REMARK 500 THIS ENTRY HAS     274 RAMACHANDRAN OUTLIERS.                        
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: NON-CIS, NON-TRANS                                         
REMARK 500                                                                      
REMARK 500 THE FOLLOWING PEPTIDE BONDS DEVIATE SIGNIFICANTLY FROM BOTH          
REMARK 500 CIS AND TRANS CONFORMATION.  CIS BONDS, IF ANY, ARE LISTED           
REMARK 500 ON CISPEP RECORDS.  TRANS IS DEFINED AS 180 +/- 30 AND               
REMARK 500 CIS IS DEFINED AS 0 +/- 30 DEGREES.                                  
REMARK 500                                 MODEL     OMEGA                      
REMARK 500 ILE C  105     PHE C  106                 -144.34                    
REMARK 500 HIS J  194     PRO J  195                 -148.42                    
REMARK 500 HIS P    5     ARG P    6                 -147.71                    
REMARK 500 LYS o  239     VAL o  240                 -147.69                    
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 620                                                                      
REMARK 620 METAL COORDINATION                                                   
REMARK 620 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 620 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE):                             
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 61002  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   G 6  60   OP2                                                    
REMARK 620 2   U 6  80   OP1 132.5                                              
REMARK 620 3   U 6  80   OP2  89.4  62.0                                        
REMARK 620 N                    1     2                                         
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 61003  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   C 6  61   OP1                                                    
REMARK 620 2   G 6  77   OP1  70.4                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              MG 61001  MG                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1   G 6  78   OP1                                                    
REMARK 620 2   U 6  80   OP2 133.7                                              
REMARK 620 N                    1                                               
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              ZN L1000  ZN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS L 104   SG                                                     
REMARK 620 2 CYS L 105   SG  126.7                                              
REMARK 620 3 CYS L 108   SG   89.7 124.8                                        
REMARK 620 4 CYS L 148   SG   87.7 118.3 100.8                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              ZN L1001  ZN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS L 104   SG                                                     
REMARK 620 2 CYS L 122   SG  141.1                                              
REMARK 620 3 CYS L 150   SG  107.0 105.0                                        
REMARK 620 4 CYS L 153   SG   88.4 112.8  90.6                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              ZN L1002  ZN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS L 108   SG                                                     
REMARK 620 2 CYS L 120   SG  107.6                                              
REMARK 620 3 CYS L 122   SG  111.8  75.8                                        
REMARK 620 4 CYS L 145   SG  107.0  92.0 141.2                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              ZN M1000  ZN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS M  73   SG                                                     
REMARK 620 2 CYS M  81   SG  104.9                                              
REMARK 620 3 CYS M  87   SG  111.3 117.0                                        
REMARK 620 4 HIS M  91   NE2 122.5  98.7 102.6                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              ZN N 402  ZN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS N  13   SG                                                     
REMARK 620 2 CYS N  16   SG  115.5                                              
REMARK 620 3 CYS N  71   SG  120.8 120.8                                        
REMARK 620 4 CYS N  74   SG   86.8  65.0 100.7                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              ZN N 401  ZN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS N  34   SG                                                     
REMARK 620 2 CYS N  37   SG   86.7                                              
REMARK 620 3 CYS N  61   SG  129.8  96.3                                        
REMARK 620 4 CYS N  64   SG  140.4  92.4  89.7                                  
REMARK 620 N                    1     2     3                                   
REMARK 800                                                                      
REMARK 800 SITE                                                                 
REMARK 800 SITE_IDENTIFIER: AC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue MG 6 1001                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue MG 6 1002                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC3                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue MG 6 1003                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC4                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue K 6 1004                  
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC5                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue K 6 1005                  
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC6                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue I6P A 3001                
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC7                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue GTP C 1101                
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC8                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue ZN L 1000                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC9                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue ZN L 1001                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AD1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue ZN L 1002                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AD2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue ZN M 1000                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AD3                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue ZN N 401                  
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AD4                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue ZN N 402                  
REMARK 900                                                                      
REMARK 900 RELATED ENTRIES                                                      
REMARK 900 RELATED ID: EMD-3539   RELATED DB: EMDB                              
REMARK 900 STRUCTURE OF A SPLICEOSOME REMODELED FOR EXON LIGATION               
DBREF  5MPS I    1    95  GB     4718     X17493.1       594    688             
DBREF  5MPS E  -20    -1  PDB    5MPS     5MPS           -20     -1             
DBREF  5MPS 2    1  1175  GB     536627   Z36099.1      2641   1467             
DBREF1 5MPS 6    1   112  GB                   CP007856.1                       
DBREF2 5MPS 6     1039022925                     365627      365738             
DBREF1 5MPS 5    1   179  GB                   CP008157.1                       
DBREF2 5MPS 5     1039023700                     939472      939294             
DBREF  5MPS A    1  2413  UNP    P33334   PRP8_YEAST       1   2413             
DBREF  5MPS C    1  1008  UNP    P36048   SN114_YEAST      1   1008             
DBREF  5MPS H    1   577  UNP    P53333   CWC22_YEAST      1    577             
DBREF  5MPS J    1   451  UNP    Q12417   PRP46_YEAST      1    451             
DBREF  5MPS K    1   379  UNP    P28004   PRP45_YEAST      1    379             
DBREF  5MPS L    1   157  UNP    P25337   BUD31_YEAST      1    157             
DBREF  5MPS M    1   339  UNP    Q12046   CWC2_YEAST       1    339             
DBREF  5MPS N    1   364  UNP    P38241   SLT11_YEAST      1    364             
DBREF  5MPS O    1   590  UNP    Q03654   CEF1_YEAST       1    590             
DBREF  5MPS P    1   175  UNP    Q03772   CWC15_YEAST      1    175             
DBREF  5MPS R    1   135  UNP    Q03375   CWC21_YEAST      1    135             
DBREF  5MPS S    1   687  UNP    Q12309   CLF1_YEAST       1    687             
DBREF  5MPS T    1   859  UNP    Q04048   SYF1_YEAST       1    859             
DBREF  5MPS a    1   251  UNP    P33411   PRP18_YEAST      1    251             
DBREF  5MPS c    1   382  UNP    Q02775   SLU7_YEAST       1    382             
DBREF  5MPS o    1   455  UNP    P40968   PRP17_YEAST      1    455             
DBREF  5MPS X    4   129  PDB    5MPS     5MPS             4    129             
DBREF  5MPS y    1   215  UNP    P53277   SYF2_YEAST       1    215             
DBREF  5MPS b    1   196  UNP    P40018   RSMB_YEAST       1    196             
DBREF  5MPS d    1   101  UNP    P43321   SMD3_YEAST       1    101             
DBREF  5MPS e    1    94  UNP    Q12330   RUXE_YEAST       1     94             
DBREF  5MPS f    1    86  UNP    P54999   RUXF_YEAST       1     86             
DBREF  5MPS g    1    77  UNP    P40204   RUXG_YEAST       1     77             
DBREF  5MPS h    1   146  UNP    Q02260   SMD1_YEAST       1    146             
DBREF  5MPS j    1   110  UNP    Q06217   SMD2_YEAST       1    110             
DBREF  5MPS T 1000  1017  PDB    5MPS     5MPS          1000   1017             
SEQRES   1 I   95    G   U   A   U   G   U   C   U   A   A   A   G   U          
SEQRES   2 I   95    U   A   U   G   G   C   C   A   C   G   U   U   U          
SEQRES   3 I   95    C   A   A   A   U   G   C   G   U   G   C   U   U          
SEQRES   4 I   95    U   U   U   U   U   U   U   A   A   A   A   C   U          
SEQRES   5 I   95    U   A   U   G   C   U   C   U   U   A   U   U   U          
SEQRES   6 I   95    A   C   U   A   A   C   A   A   A   A   U   C   A          
SEQRES   7 I   95    A   C   A   U   G   C   U   A   U   U   G   A   A          
SEQRES   8 I   95    C   U   A   G                                              
SEQRES   1 E   20    G   A   A   G   U   A   A   G   U   G   A   U   C          
SEQRES   2 E   20    U   A   G   A   A   A   G                                  
SEQRES   1 2 1175    A   C   G   A   A   U   C   U   C   U   U   U   G          
SEQRES   2 2 1175    C   C   U   U   U   U   G   G   C   U   U   A   G          
SEQRES   3 2 1175    A   U   C   A   A   G   U   G   U   A   G   U   A          
SEQRES   4 2 1175    U   C   U   G   U   U   C   U   U   U   U   C   A          
SEQRES   5 2 1175    G   U   G   U   A   A   C   A   A   C   U   G   A          
SEQRES   6 2 1175    A   A   U   G   A   C   C   U   C   A   A   U   G          
SEQRES   7 2 1175    A   G   G   C   U   C   A   U   U   A   C   C   U          
SEQRES   8 2 1175    U   U   U   A   A   U   U   U   G   U   U   A   C          
SEQRES   9 2 1175    A   A   U   A   C   A   C   A   U   U   U   U   U          
SEQRES  10 2 1175    U   G   G   C   A   C   C   C   A   A   A   A   U          
SEQRES  11 2 1175    A   A   U   A   A   A   A   U   G   G   A   C   G          
SEQRES  12 2 1175    G   G   A   A   G   A   G   A   C   U   U   U   U          
SEQRES  13 2 1175    U   A   A   G   C   A   A   G   U   U   G   U   U          
SEQRES  14 2 1175    U   U   C   C   G   C   U   A   A   U   G   U   C          
SEQRES  15 2 1175    A   G   G   U   C   U   C   A   C   U   A   C   U          
SEQRES  16 2 1175    U   U   U   U   G   C   U   G   C   U   A   U   U          
SEQRES  17 2 1175    U   U   U   C   U   U   C   G   C   U   C   A   U          
SEQRES  18 2 1175    G   G   U   U   U   C   U   U   C   A   U   A   A          
SEQRES  19 2 1175    G   G   C   G   U   U   U   U   U   A   U   G   A          
SEQRES  20 2 1175    U   G   G   U   U   U   U   U   C   G   A   A   A          
SEQRES  21 2 1175    U   U   G   G   U   U   U   U   U   G   A   G   A          
SEQRES  22 2 1175    C   G   A   C   G   G   U   U   G   C   U   C   A          
SEQRES  23 2 1175    A   G   G   U   U   A   U   U   G   U   U   U   U          
SEQRES  24 2 1175    U   G   U   U   U   U   C   U   U   C   U   G   G          
SEQRES  25 2 1175    U   U   G   U   U   U   U   C   U   A   U   U   U          
SEQRES  26 2 1175    U   C   U   U   U   U   U   U   U   U   A   G   C          
SEQRES  27 2 1175    U   U   U   C   U   G   U   U   U   C   U   C   C          
SEQRES  28 2 1175    C   U   U   A   G   U   U   U   G   G   C   U   U          
SEQRES  29 2 1175    U   U   U   G   C   U   U   C   A   U   A   C   U          
SEQRES  30 2 1175    C   U   U   C   C   C   U   G   U   C   U   U   U          
SEQRES  31 2 1175    C   C   G   A   G   C   C   G   U   U   U   A   U          
SEQRES  32 2 1175    G   U   C   C   A   A   C   G   C   G   G   G   A          
SEQRES  33 2 1175    U   U   U   G   G   U   U   U   U   U   C   U   U          
SEQRES  34 2 1175    U   A   U   C   G   A   U   G   G   G   A   A   G          
SEQRES  35 2 1175    A   A   A   U   G   G   U   G   C   U   A   U   A          
SEQRES  36 2 1175    G   U   A   G   G   U   U   G   G   G   A   G   A          
SEQRES  37 2 1175    U   A   A   U   A   U   U   U   A   U   G   G   U          
SEQRES  38 2 1175    A   U   G   G   G   G   U   G   C   U   A   G   U          
SEQRES  39 2 1175    G   C   G   G   A   U   G   G   G   G   C   G   C          
SEQRES  40 2 1175    U   C   U   U   A   U   U   G   U   U   G   A   U          
SEQRES  41 2 1175    U   U   C   U   U   C   G   C   U   C   G   U   C          
SEQRES  42 2 1175    U   U   C   U   U   U   U   U   C   U   G   G   U          
SEQRES  43 2 1175    G   G   C   G   C   U   G   C   A   A   G   A   G          
SEQRES  44 2 1175    G   A   A   G   U   U   U   U   U   C   G   A   C          
SEQRES  45 2 1175    U   U   U   G   U   U   A   U   G   A   U   U   U          
SEQRES  46 2 1175    U   U   G   G   U   U   U   G   C   A   A   G   G          
SEQRES  47 2 1175    A   A   A   G   G   U   G   U   C   U   U   A   C          
SEQRES  48 2 1175    G   A   U   U   C   U   U   U   U   U   U   U   G          
SEQRES  49 2 1175    A   U   G   U   A   A   U   A   G   G   A   U   A          
SEQRES  50 2 1175    A   G   C   U   U   G   C   U   U   A   U   C   C          
SEQRES  51 2 1175    C   C   C   A   A   G   U   A   U   C   G   G   C          
SEQRES  52 2 1175    C   A   A   A   G   U   U   G   U   U   G   A   U          
SEQRES  53 2 1175    U   U   U   C   C   U   U   U   U   G   A   A   G          
SEQRES  54 2 1175    U   G   U   C   C   U   C   G   G   U   U   U   G          
SEQRES  55 2 1175    A   G   G   G   G   G   U   G   U   A   G   G   G          
SEQRES  56 2 1175    U   G   G   G   G   U   U   G   G   U   C   U   A          
SEQRES  57 2 1175    C   A   A   U   A   A   G   A   G   U   G   U   U          
SEQRES  58 2 1175    C   C   A   U   U   G   U   U   A   A   C   G   U          
SEQRES  59 2 1175    G   C   U   G   G   C   G   U   C   U   U   U   U          
SEQRES  60 2 1175    A   C   U   A   U   A   U   U   U   U   U   U   U          
SEQRES  61 2 1175    U   C   C   C   A   G   U   U   U   A   U   U   U          
SEQRES  62 2 1175    U   G   U   G   C   U   U   A   U   U   U   U   C          
SEQRES  63 2 1175    U   C   A   U   U   G   A   G   G   A   G   A   A          
SEQRES  64 2 1175    G   G   A   G   C   U   C   U   U   C   U   C   G          
SEQRES  65 2 1175    C   A   G   G   A   U   A   U   A   A   A   U   G          
SEQRES  66 2 1175    G   A   G   G   U   U   U   G   C   U   A   A   A          
SEQRES  67 2 1175    G   G   G   G   A   G   G   A   G   A   U   G   U          
SEQRES  68 2 1175    G   U   U   U   G   U   G   A   G   A   A   U   A          
SEQRES  69 2 1175    C   U   G   C   U   G   A   G   A   G   A   G   U          
SEQRES  70 2 1175    U   C   U   G   G   A   A   G   A   G   A   A   A          
SEQRES  71 2 1175    A   A   A   A   G   G   A   G   G   C   A   A   U          
SEQRES  72 2 1175    G   G   A   A   G   G   C   G   U   U   U   G   C          
SEQRES  73 2 1175    U   G   G   G   A   A   A   A   G   A   G   A   A          
SEQRES  74 2 1175    G   A   G   C   C   A   U   G   A   C   U   G   C          
SEQRES  75 2 1175    A   U   C   U   G   U   U   G   U   U   U   C   A          
SEQRES  76 2 1175    A   G   G   C   C   A   G   U   U   U   U   A   U          
SEQRES  77 2 1175    U   A   A   C   C   G   C   C   U   A   U   G   U          
SEQRES  78 2 1175    C   A   U   A   G   A   G   G   C   G   U   U   U          
SEQRES  79 2 1175    U   U   U   U   U   G   G   A   G   G   G   A   U          
SEQRES  80 2 1175    U   U   G   A   A   G   A   A   U   G   C   C   G          
SEQRES  81 2 1175    G   C   G   G   C   A   U   C   A   A   G   A   A          
SEQRES  82 2 1175    A   C   G   G   A   C   U   U   G   A   U   G   G          
SEQRES  83 2 1175    U   U   G   A   C   G   C   C   U   G   U   U   U          
SEQRES  84 2 1175    U   U   A   A   A   G   U   U   A   G   A   G   A          
SEQRES  85 2 1175    C   G   U   C   G   C   G   A   C   C   C   U   C          
SEQRES  86 2 1175    G   C   A   C   U   U   G   U   G   G   A   G   U          
SEQRES  87 2 1175    C   G   U   U   C   U   U   G   A   C   U   U   U          
SEQRES  88 2 1175    U   A   C   U   U   U   G   G   U   C   G   C   U          
SEQRES  89 2 1175    U   G   A   U   G   U   U   U   C   U   C   U   C          
SEQRES  90 2 1175    G   U   C   U   U   C   C   C   G   U   U   C   G          
SEQRES  91 2 1175    C   U   C   U   U                                          
SEQRES   1 6  112    G   U   U   C   G   C   G   A   A   G   U   A   A          
SEQRES   2 6  112    C   C   C   U   U   C   G   U   G   G   A   C   A          
SEQRES   3 6  112    U   U   U   G   G   U   C   A   A   U   U   U   G          
SEQRES   4 6  112    A   A   A   C   A   A   U   A   C   A   G   A   G          
SEQRES   5 6  112    A   U   G   A   U   C   A   G   C   A   G   U   U          
SEQRES   6 6  112    C   C   C   C   U   G   C   A   U   A   A   G   G          
SEQRES   7 6  112    A   U   G   A   A   C   C   G   U   U   U   U   A          
SEQRES   8 6  112    C   A   A   A   G   A   G   A   U   U   U   A   U          
SEQRES   9 6  112    U   U   C   G   U   U   U   U                              
SEQRES   1 5  179    A   A   G   C   A   G   C   U   U   U   A   C   A          
SEQRES   2 5  179    G   A   U   C   A   A   U   G   G   C   G   G   A          
SEQRES   3 5  179    G   G   G   A   G   G   U   C   A   A   C   A   U          
SEQRES   4 5  179    C   A   A   G   A   A   C   U   G   U   G   G   G          
SEQRES   5 5  179    C   C   U   U   U   U   A   U   U   G   C   C   U          
SEQRES   6 5  179    A   U   A   G   A   A   C   U   U   A   U   A   A          
SEQRES   7 5  179    C   G   A   A   C   A   U   G   G   U   U   C   U          
SEQRES   8 5  179    U   G   C   C   U   U   U   U   A   C   C   A   G          
SEQRES   9 5  179    A   A   C   C   A   U   C   C   G   G   G   U   G          
SEQRES  10 5  179    U   U   G   U   C   U   C   C   A   U   A   G   A          
SEQRES  11 5  179    A   A   C   A   G   G   U   A   A   A   G   C   U          
SEQRES  12 5  179    G   U   C   C   G   U   U   A   C   U   G   U   G          
SEQRES  13 5  179    G   G   C   U   U   G   C   C   A   U   A   U   U          
SEQRES  14 5  179    U   U   U   U   G   G   A   A   C   U                      
SEQRES   1 A 2413  MET SER GLY LEU PRO PRO PRO PRO PRO GLY PHE GLU GLU          
SEQRES   2 A 2413  ASP SER ASP LEU ALA LEU PRO PRO PRO PRO PRO PRO PRO          
SEQRES   3 A 2413  PRO GLY TYR GLU ILE GLU GLU LEU ASP ASN PRO MET VAL          
SEQRES   4 A 2413  PRO SER SER VAL ASN GLU ASP THR PHE LEU PRO PRO PRO          
SEQRES   5 A 2413  PRO PRO PRO PRO SER ASN PHE GLU ILE ASN ALA GLU GLU          
SEQRES   6 A 2413  ILE VAL ASP PHE THR LEU PRO PRO PRO PRO PRO PRO PRO          
SEQRES   7 A 2413  GLY LEU ASP GLU LEU GLU THR LYS ALA GLU LYS LYS VAL          
SEQRES   8 A 2413  GLU LEU HIS GLY LYS ARG LYS LEU ASP ILE GLY LYS ASP          
SEQRES   9 A 2413  THR PHE VAL THR ARG LYS SER ARG LYS ARG ALA LYS LYS          
SEQRES  10 A 2413  MET THR LYS LYS ALA LYS ARG SER ASN LEU TYR THR PRO          
SEQRES  11 A 2413  LYS ALA GLU MET PRO PRO GLU HIS LEU ARG LYS ILE ILE          
SEQRES  12 A 2413  ASN THR HIS SER ASP MET ALA SER LYS MET TYR ASN THR          
SEQRES  13 A 2413  ASP LYS LYS ALA PHE LEU GLY ALA LEU LYS TYR LEU PRO          
SEQRES  14 A 2413  HIS ALA ILE LEU LYS LEU LEU GLU ASN MET PRO HIS PRO          
SEQRES  15 A 2413  TRP GLU GLN ALA LYS GLU VAL LYS VAL LEU TYR HIS THR          
SEQRES  16 A 2413  SER GLY ALA ILE THR PHE VAL ASN GLU THR PRO ARG VAL          
SEQRES  17 A 2413  ILE GLU PRO VAL TYR THR ALA GLN TRP SER ALA THR TRP          
SEQRES  18 A 2413  ILE ALA MET ARG ARG GLU LYS ARG ASP ARG THR HIS PHE          
SEQRES  19 A 2413  LYS ARG MET ARG PHE PRO PRO PHE ASP ASP ASP GLU PRO          
SEQRES  20 A 2413  PRO LEU SER TYR GLU GLN HIS ILE GLU ASN ILE GLU PRO          
SEQRES  21 A 2413  LEU ASP PRO ILE ASN LEU PRO LEU ASP SER GLN ASP ASP          
SEQRES  22 A 2413  GLU TYR VAL LYS ASP TRP LEU TYR ASP SER ARG PRO LEU          
SEQRES  23 A 2413  GLU GLU ASP SER LYS LYS VAL ASN GLY THR SER TYR LYS          
SEQRES  24 A 2413  LYS TRP SER PHE ASP LEU PRO GLU MET SER ASN LEU TYR          
SEQRES  25 A 2413  ARG LEU SER THR PRO LEU ARG ASP GLU VAL THR ASP LYS          
SEQRES  26 A 2413  ASN TYR TYR TYR LEU PHE ASP LYS LYS SER PHE PHE ASN          
SEQRES  27 A 2413  GLY LYS ALA LEU ASN ASN ALA ILE PRO GLY GLY PRO LYS          
SEQRES  28 A 2413  PHE GLU PRO LEU TYR PRO ARG GLU GLU GLU GLU ASP TYR          
SEQRES  29 A 2413  ASN GLU PHE ASN SER ILE ASP ARG VAL ILE PHE ARG VAL          
SEQRES  30 A 2413  PRO ILE ARG SER GLU TYR LYS VAL ALA PHE PRO HIS LEU          
SEQRES  31 A 2413  TYR ASN SER ARG PRO ARG SER VAL ARG ILE PRO TRP TYR          
SEQRES  32 A 2413  ASN ASN PRO VAL SER CYS ILE ILE GLN ASN ASP GLU GLU          
SEQRES  33 A 2413  TYR ASP THR PRO ALA LEU PHE PHE ASP PRO SER LEU ASN          
SEQRES  34 A 2413  PRO ILE PRO HIS PHE ILE ASP ASN ASN SER SER LEU ASN          
SEQRES  35 A 2413  VAL SER ASN THR LYS GLU ASN GLY ASP PHE THR LEU PRO          
SEQRES  36 A 2413  GLU ASP PHE ALA PRO LEU LEU ALA GLU GLU GLU GLU LEU          
SEQRES  37 A 2413  ILE LEU PRO ASN THR LYS ASP ALA MET SER LEU TYR HIS          
SEQRES  38 A 2413  SER PRO PHE PRO PHE ASN ARG THR LYS GLY LYS MET VAL          
SEQRES  39 A 2413  ARG ALA GLN ASP VAL ALA LEU ALA LYS LYS TRP PHE LEU          
SEQRES  40 A 2413  GLN HIS PRO ASP GLU GLU TYR PRO VAL LYS VAL LYS VAL          
SEQRES  41 A 2413  SER TYR GLN LYS LEU LEU LYS ASN TYR VAL LEU ASN GLU          
SEQRES  42 A 2413  LEU HIS PRO THR LEU PRO THR ASN HIS ASN LYS THR LYS          
SEQRES  43 A 2413  LEU LEU LYS SER LEU LYS ASN THR LYS TYR PHE GLN GLN          
SEQRES  44 A 2413  THR THR ILE ASP TRP VAL GLU ALA GLY LEU GLN LEU CYS          
SEQRES  45 A 2413  ARG GLN GLY HIS ASN MET LEU ASN LEU LEU ILE HIS ARG          
SEQRES  46 A 2413  LYS GLY LEU THR TYR LEU HIS LEU ASP TYR ASN PHE ASN          
SEQRES  47 A 2413  LEU LYS PRO THR LYS THR LEU THR THR LYS GLU ARG LYS          
SEQRES  48 A 2413  LYS SER ARG LEU GLY ASN SER PHE HIS LEU MET ARG GLU          
SEQRES  49 A 2413  LEU LEU LYS MET MET LYS LEU ILE VAL ASP THR HIS VAL          
SEQRES  50 A 2413  GLN PHE ARG LEU GLY ASN VAL ASP ALA PHE GLN LEU ALA          
SEQRES  51 A 2413  ASP GLY ILE HIS TYR ILE LEU ASN HIS ILE GLY GLN LEU          
SEQRES  52 A 2413  THR GLY ILE TYR ARG TYR LYS TYR LYS VAL MET HIS GLN          
SEQRES  53 A 2413  ILE ARG ALA CYS LYS ASP LEU LYS HIS ILE ILE TYR TYR          
SEQRES  54 A 2413  LYS PHE ASN LYS ASN LEU GLY LYS GLY PRO GLY CYS GLY          
SEQRES  55 A 2413  PHE TRP GLN PRO ALA TRP ARG VAL TRP LEU ASN PHE LEU          
SEQRES  56 A 2413  ARG GLY THR ILE PRO LEU LEU GLU ARG TYR ILE GLY ASN          
SEQRES  57 A 2413  LEU ILE THR ARG GLN PHE GLU GLY ARG SER ASN GLU ILE          
SEQRES  58 A 2413  VAL LYS THR THR THR LYS GLN ARG LEU ASP ALA TYR TYR          
SEQRES  59 A 2413  ASP LEU GLU LEU ARG ASN SER VAL MET ASP ASP ILE LEU          
SEQRES  60 A 2413  GLU MET MET PRO GLU SER ILE ARG GLN LYS LYS ALA ARG          
SEQRES  61 A 2413  THR ILE LEU GLN HIS LEU SER GLU ALA TRP ARG CYS TRP          
SEQRES  62 A 2413  LYS ALA ASN ILE PRO TRP ASP VAL PRO GLY MET PRO ALA          
SEQRES  63 A 2413  PRO ILE LYS LYS ILE ILE GLU ARG TYR ILE LYS SER LYS          
SEQRES  64 A 2413  ALA ASP ALA TRP VAL SER ALA ALA HIS TYR ASN ARG GLU          
SEQRES  65 A 2413  ARG ILE LYS ARG GLY ALA HIS VAL GLU LYS THR MET VAL          
SEQRES  66 A 2413  LYS LYS ASN LEU GLY ARG LEU THR ARG LEU TRP ILE LYS          
SEQRES  67 A 2413  ASN GLU GLN GLU ARG GLN ARG GLN ILE GLN LYS ASN GLY          
SEQRES  68 A 2413  PRO GLU ILE THR PRO GLU GLU ALA THR THR ILE PHE SER          
SEQRES  69 A 2413  VAL MET VAL GLU TRP LEU GLU SER ARG SER PHE SER PRO          
SEQRES  70 A 2413  ILE PRO PHE PRO PRO LEU THR TYR LYS ASN ASP THR LYS          
SEQRES  71 A 2413  ILE LEU VAL LEU ALA LEU GLU ASP LEU LYS ASP VAL TYR          
SEQRES  72 A 2413  ALA SER LYS VAL ARG LEU ASN ALA SER GLU ARG GLU GLU          
SEQRES  73 A 2413  LEU ALA LEU ILE GLU GLU ALA TYR ASP ASN PRO HIS ASP          
SEQRES  74 A 2413  THR LEU ASN ARG ILE LYS LYS TYR LEU LEU THR GLN ARG          
SEQRES  75 A 2413  VAL PHE LYS PRO VAL ASP ILE THR MET MET GLU ASN TYR          
SEQRES  76 A 2413  GLN ASN ILE SER PRO VAL TYR SER VAL ASP PRO LEU GLU          
SEQRES  77 A 2413  LYS ILE THR ASP ALA TYR LEU ASP GLN TYR LEU TRP TYR          
SEQRES  78 A 2413  GLU ALA ASP GLN ARG LYS LEU PHE PRO ASN TRP ILE LYS          
SEQRES  79 A 2413  PRO SER ASP SER GLU ILE PRO PRO LEU LEU VAL TYR LYS          
SEQRES  80 A 2413  TRP THR GLN GLY ILE ASN ASN LEU SER GLU ILE TRP ASP          
SEQRES  81 A 2413  VAL SER ARG GLY GLN SER ALA VAL LEU LEU GLU THR THR          
SEQRES  82 A 2413  LEU GLY GLU MET ALA GLU LYS ILE ASP PHE THR LEU LEU          
SEQRES  83 A 2413  ASN ARG LEU LEU ARG LEU ILE VAL ASP PRO ASN ILE ALA          
SEQRES  84 A 2413  ASP TYR ILE THR ALA LYS ASN ASN VAL VAL ILE ASN PHE          
SEQRES  85 A 2413  LYS ASP MET SER HIS VAL ASN LYS TYR GLY LEU ILE ARG          
SEQRES  86 A 2413  GLY LEU LYS PHE ALA SER PHE ILE PHE GLN TYR TYR GLY          
SEQRES  87 A 2413  LEU VAL ILE ASP LEU LEU LEU LEU GLY GLN GLU ARG ALA          
SEQRES  88 A 2413  THR ASP LEU ALA GLY PRO ALA ASN ASN PRO ASN GLU PHE          
SEQRES  89 A 2413  MET GLN PHE LYS SER LYS GLU VAL GLU LYS ALA HIS PRO          
SEQRES  90 A 2413  ILE ARG LEU TYR THR ARG TYR LEU ASP ARG ILE TYR MET          
SEQRES  91 A 2413  LEU PHE HIS PHE GLU GLU ASP GLU GLY GLU GLU LEU THR          
SEQRES  92 A 2413  ASP GLU TYR LEU ALA GLU ASN PRO ASP PRO ASN PHE GLU          
SEQRES  93 A 2413  ASN SER ILE GLY TYR ASN ASN ARG LYS CYS TRP PRO LYS          
SEQRES  94 A 2413  ASP SER ARG MET ARG LEU ILE ARG GLN ASP VAL ASN LEU          
SEQRES  95 A 2413  GLY ARG ALA VAL PHE TRP GLU ILE GLN SER ARG VAL PRO          
SEQRES  96 A 2413  THR SER LEU THR SER ILE LYS TRP GLU ASN ALA PHE VAL          
SEQRES  97 A 2413  SER VAL TYR SER LYS ASN ASN PRO ASN LEU LEU PHE SER          
SEQRES  98 A 2413  MET CYS GLY PHE GLU VAL ARG ILE LEU PRO ARG GLN ARG          
SEQRES  99 A 2413  MET GLU GLU VAL VAL SER ASN ASP GLU GLY VAL TRP ASP          
SEQRES 100 A 2413  LEU VAL ASP GLU ARG THR LYS GLN ARG THR ALA LYS ALA          
SEQRES 101 A 2413  TYR LEU LYS VAL SER GLU GLU GLU ILE LYS LYS PHE ASP          
SEQRES 102 A 2413  SER ARG ILE ARG GLY ILE LEU MET ALA SER GLY SER THR          
SEQRES 103 A 2413  THR PHE THR LYS VAL ALA ALA LYS TRP ASN THR SER LEU          
SEQRES 104 A 2413  ILE SER LEU PHE THR TYR PHE ARG GLU ALA ILE VAL ALA          
SEQRES 105 A 2413  THR GLU PRO LEU LEU ASP ILE LEU VAL LYS GLY GLU THR          
SEQRES 106 A 2413  ARG ILE GLN ASN ARG VAL LYS LEU GLY LEU ASN SER LYS          
SEQRES 107 A 2413  MET PRO THR ARG PHE PRO PRO ALA VAL PHE TYR THR PRO          
SEQRES 108 A 2413  LYS GLU LEU GLY GLY LEU GLY MET ILE SER ALA SER HIS          
SEQRES 109 A 2413  ILE LEU ILE PRO ALA SER ASP LEU SER TRP SER LYS GLN          
SEQRES 110 A 2413  THR ASP THR GLY ILE THR HIS PHE ARG ALA GLY MET THR          
SEQRES 111 A 2413  HIS GLU ASP GLU LYS LEU ILE PRO THR ILE PHE ARG TYR          
SEQRES 112 A 2413  ILE THR THR TRP GLU ASN GLU PHE LEU ASP SER GLN ARG          
SEQRES 113 A 2413  VAL TRP ALA GLU TYR ALA THR LYS ARG GLN GLU ALA ILE          
SEQRES 114 A 2413  GLN GLN ASN ARG ARG LEU ALA PHE GLU GLU LEU GLU GLY          
SEQRES 115 A 2413  SER TRP ASP ARG GLY ILE PRO ARG ILE SER THR LEU PHE          
SEQRES 116 A 2413  GLN ARG ASP ARG HIS THR LEU ALA TYR ASP ARG GLY HIS          
SEQRES 117 A 2413  ARG ILE ARG ARG GLU PHE LYS GLN TYR SER LEU GLU ARG          
SEQRES 118 A 2413  ASN SER PRO PHE TRP TRP THR ASN SER HIS HIS ASP GLY          
SEQRES 119 A 2413  LYS LEU TRP ASN LEU ASN ALA TYR ARG THR ASP VAL ILE          
SEQRES 120 A 2413  GLN ALA LEU GLY GLY ILE GLU THR ILE LEU GLU HIS THR          
SEQRES 121 A 2413  LEU PHE LYS GLY THR GLY PHE ASN SER TRP GLU GLY LEU          
SEQRES 122 A 2413  PHE TRP GLU LYS ALA SER GLY PHE GLU ASP SER MET GLN          
SEQRES 123 A 2413  PHE LYS LYS LEU THR HIS ALA GLN ARG THR GLY LEU SER          
SEQRES 124 A 2413  GLN ILE PRO ASN ARG ARG PHE THR LEU TRP TRP SER PRO          
SEQRES 125 A 2413  THR ILE ASN ARG ALA ASN VAL TYR VAL GLY PHE LEU VAL          
SEQRES 126 A 2413  GLN LEU ASP LEU THR GLY ILE PHE LEU HIS GLY LYS ILE          
SEQRES 127 A 2413  PRO THR LEU LYS ILE SER LEU ILE GLN ILE PHE ARG ALA          
SEQRES 128 A 2413  HIS LEU TRP GLN LYS ILE HIS GLU SER ILE VAL PHE ASP          
SEQRES 129 A 2413  ILE CYS GLN ILE LEU ASP GLY GLU LEU ASP VAL LEU GLN          
SEQRES 130 A 2413  ILE GLU SER VAL THR LYS GLU THR VAL HIS PRO ARG LYS          
SEQRES 131 A 2413  SER TYR LYS MET ASN SER SER ALA ALA ASP ILE THR MET          
SEQRES 132 A 2413  GLU SER VAL HIS GLU TRP GLU VAL SER LYS PRO SER LEU          
SEQRES 133 A 2413  LEU HIS GLU THR ASN ASP SER PHE LYS GLY LEU ILE THR          
SEQRES 134 A 2413  ASN LYS MET TRP PHE ASP VAL GLN LEU ARG TYR GLY ASP          
SEQRES 135 A 2413  TYR ASP SER HIS ASP ILE SER ARG TYR VAL ARG ALA LYS          
SEQRES 136 A 2413  PHE LEU ASP TYR THR THR ASP ASN VAL SER MET TYR PRO          
SEQRES 137 A 2413  SER PRO THR GLY VAL MET ILE GLY ILE ASP LEU ALA TYR          
SEQRES 138 A 2413  ASN MET TYR ASP ALA TYR GLY ASN TRP PHE ASN GLY LEU          
SEQRES 139 A 2413  LYS PRO LEU ILE GLN ASN SER MET ARG THR ILE MET LYS          
SEQRES 140 A 2413  ALA ASN PRO ALA LEU TYR VAL LEU ARG GLU ARG ILE ARG          
SEQRES 141 A 2413  LYS GLY LEU GLN ILE TYR GLN SER SER VAL GLN GLU PRO          
SEQRES 142 A 2413  PHE LEU ASN SER SER ASN TYR ALA GLU LEU PHE ASN ASN          
SEQRES 143 A 2413  ASP ILE LYS LEU PHE VAL ASP ASP THR ASN VAL TYR ARG          
SEQRES 144 A 2413  VAL THR VAL HIS LYS THR PHE GLU GLY ASN VAL ALA THR          
SEQRES 145 A 2413  LYS ALA ILE ASN GLY CYS ILE PHE THR LEU ASN PRO LYS          
SEQRES 146 A 2413  THR GLY HIS LEU PHE LEU LYS ILE ILE HIS THR SER VAL          
SEQRES 147 A 2413  TRP ALA GLY GLN LYS ARG LEU SER GLN LEU ALA LYS TRP          
SEQRES 148 A 2413  LYS THR ALA GLU GLU VAL SER ALA LEU VAL ARG SER LEU          
SEQRES 149 A 2413  PRO LYS GLU GLU GLN PRO LYS GLN ILE ILE VAL THR ARG          
SEQRES 150 A 2413  LYS ALA MET LEU ASP PRO LEU GLU VAL HIS MET LEU ASP          
SEQRES 151 A 2413  PHE PRO ASN ILE ALA ILE ARG PRO THR GLU LEU ARG LEU          
SEQRES 152 A 2413  PRO PHE SER ALA ALA MET SER ILE ASP LYS LEU SER ASP          
SEQRES 153 A 2413  VAL VAL MET LYS ALA THR GLU PRO GLN MET VAL LEU PHE          
SEQRES 154 A 2413  ASN ILE TYR ASP ASP TRP LEU ASP ARG ILE SER SER TYR          
SEQRES 155 A 2413  THR ALA PHE SER ARG LEU THR LEU LEU LEU ARG ALA LEU          
SEQRES 156 A 2413  LYS THR ASN GLU GLU SER ALA LYS MET ILE LEU LEU SER          
SEQRES 157 A 2413  ASP PRO THR ILE THR ILE LYS SER TYR HIS LEU TRP PRO          
SEQRES 158 A 2413  SER PHE THR ASP GLU GLN TRP ILE THR ILE GLU SER GLN          
SEQRES 159 A 2413  MET ARG ASP LEU ILE LEU THR GLU TYR GLY ARG LYS TYR          
SEQRES 160 A 2413  ASN VAL ASN ILE SER ALA LEU THR GLN THR GLU ILE LYS          
SEQRES 161 A 2413  ASP ILE ILE LEU GLY GLN ASN ILE LYS ALA PRO SER VAL          
SEQRES 162 A 2413  LYS ARG GLN LYS MET ALA GLU LEU GLU ALA ALA ARG SER          
SEQRES 163 A 2413  GLU LYS GLN ASN ASP GLU GLU ALA ALA GLY ALA SER THR          
SEQRES 164 A 2413  VAL MET LYS THR LYS THR ILE ASN ALA GLN GLY GLU GLU          
SEQRES 165 A 2413  ILE VAL VAL VAL ALA SER ALA ASP TYR GLU SER GLN THR          
SEQRES 166 A 2413  PHE SER SER LYS ASN GLU TRP ARG LYS SER ALA ILE ALA          
SEQRES 167 A 2413  ASN THR LEU LEU TYR LEU ARG LEU LYS ASN ILE TYR VAL          
SEQRES 168 A 2413  SER ALA ASP ASP PHE VAL GLU GLU GLN ASN VAL TYR VAL          
SEQRES 169 A 2413  LEU PRO LYS ASN LEU LEU LYS LYS PHE ILE GLU ILE SER          
SEQRES 170 A 2413  ASP VAL LYS ILE GLN VAL ALA ALA PHE ILE TYR GLY MET          
SEQRES 171 A 2413  SER ALA LYS ASP HIS PRO LYS VAL LYS GLU ILE LYS THR          
SEQRES 172 A 2413  VAL VAL LEU VAL PRO GLN LEU GLY HIS VAL GLY SER VAL          
SEQRES 173 A 2413  GLN ILE SER ASN ILE PRO ASP ILE GLY ASP LEU PRO ASP          
SEQRES 174 A 2413  THR GLU GLY LEU GLU LEU LEU GLY TRP ILE HIS THR GLN          
SEQRES 175 A 2413  THR GLU GLU LEU LYS PHE MET ALA ALA SER GLU VAL ALA          
SEQRES 176 A 2413  THR HIS SER LYS LEU PHE ALA ASP LYS LYS ARG ASP CYS          
SEQRES 177 A 2413  ILE ASP ILE SER ILE PHE SER THR PRO GLY SER VAL SER          
SEQRES 178 A 2413  LEU SER ALA TYR ASN LEU THR ASP GLU GLY TYR GLN TRP          
SEQRES 179 A 2413  GLY GLU GLU ASN LYS ASP ILE MET ASN VAL LEU SER GLU          
SEQRES 180 A 2413  GLY PHE GLU PRO THR PHE SER THR HIS ALA GLN LEU LEU          
SEQRES 181 A 2413  LEU SER ASP ARG ILE THR GLY ASN PHE ILE ILE PRO SER          
SEQRES 182 A 2413  GLY ASN VAL TRP ASN TYR THR PHE MET GLY THR ALA PHE          
SEQRES 183 A 2413  ASN GLN GLU GLY ASP TYR ASN PHE LYS TYR GLY ILE PRO          
SEQRES 184 A 2413  LEU GLU PHE TYR ASN GLU MET HIS ARG PRO VAL HIS PHE          
SEQRES 185 A 2413  LEU GLN PHE SER GLU LEU ALA GLY ASP GLU GLU LEU GLU          
SEQRES 186 A 2413  ALA GLU GLN ILE ASP VAL PHE SER                              
SEQRES   1 C 1008  MET GLU GLY ASP ASP LEU PHE ASP GLU PHE GLY ASN LEU          
SEQRES   2 C 1008  ILE GLY VAL ASP PRO PHE ASP SER ASP GLU GLU GLU SER          
SEQRES   3 C 1008  VAL LEU ASP GLU GLN GLU GLN TYR GLN THR ASN THR PHE          
SEQRES   4 C 1008  GLU GLY SER GLY ASN ASN ASN GLU ILE GLU SER ARG GLN          
SEQRES   5 C 1008  LEU THR SER LEU GLY SER LYS LYS GLU LEU GLY ILE SER          
SEQRES   6 C 1008  LEU GLU HIS PRO TYR GLY LYS GLU VAL GLU VAL LEU MET          
SEQRES   7 C 1008  GLU THR LYS ASN THR GLN SER PRO GLN THR PRO LEU VAL          
SEQRES   8 C 1008  GLU PRO VAL THR GLU ARG THR LYS LEU GLN GLU HIS THR          
SEQRES   9 C 1008  ILE PHE THR GLN LEU LYS LYS ASN ILE PRO LYS THR ARG          
SEQRES  10 C 1008  TYR ASN ARG ASP TYR MET LEU SER MET ALA ASN ILE PRO          
SEQRES  11 C 1008  GLU ARG ILE ILE ASN VAL GLY VAL ILE GLY PRO LEU HIS          
SEQRES  12 C 1008  SER GLY LYS THR SER LEU MET ASP LEU LEU VAL ILE ASP          
SEQRES  13 C 1008  SER HIS LYS ARG ILE PRO ASP MET SER LYS ASN VAL GLU          
SEQRES  14 C 1008  LEU GLY TRP LYS PRO LEU ARG TYR LEU ASP ASN LEU LYS          
SEQRES  15 C 1008  GLN GLU ILE ASP ARG GLY LEU SER ILE LYS LEU ASN GLY          
SEQRES  16 C 1008  SER THR LEU LEU CYS THR ASP LEU GLU SER LYS SER ARG          
SEQRES  17 C 1008  MET ILE ASN PHE LEU ASP ALA PRO GLY HIS VAL ASN PHE          
SEQRES  18 C 1008  MET ASP GLU THR ALA VAL ALA LEU ALA ALA SER ASP LEU          
SEQRES  19 C 1008  VAL LEU ILE VAL ILE ASP VAL VAL GLU GLY VAL THR PHE          
SEQRES  20 C 1008  VAL VAL GLU GLN LEU ILE LYS GLN SER ILE LYS ASN ASN          
SEQRES  21 C 1008  VAL ALA MET CYS PHE VAL ILE ASN LYS LEU ASP ARG LEU          
SEQRES  22 C 1008  ILE LEU ASP LEU LYS LEU PRO PRO MET ASP ALA TYR LEU          
SEQRES  23 C 1008  LYS LEU ASN HIS ILE ILE ALA ASN ILE ASN SER PHE THR          
SEQRES  24 C 1008  LYS GLY ASN VAL PHE SER PRO ILE ASP ASN ASN ILE ILE          
SEQRES  25 C 1008  PHE ALA SER THR LYS LEU GLY PHE THR PHE THR ILE LYS          
SEQRES  26 C 1008  GLU PHE VAL SER TYR TYR TYR ALA HIS SER ILE PRO SER          
SEQRES  27 C 1008  SER LYS ILE ASP ASP PHE THR THR ARG LEU TRP GLY SER          
SEQRES  28 C 1008  VAL TYR TYR HIS LYS GLY ASN PHE ARG THR LYS PRO PHE          
SEQRES  29 C 1008  GLU ASN VAL GLU LYS TYR PRO THR PHE VAL GLU PHE ILE          
SEQRES  30 C 1008  LEU ILE PRO LEU TYR LYS ILE PHE SER TYR ALA LEU SER          
SEQRES  31 C 1008  MET GLU LYS ASP LYS LEU LYS ASN LEU LEU ARG SER ASN          
SEQRES  32 C 1008  PHE ARG VAL ASN LEU SER GLN GLU ALA LEU GLN TYR ASP          
SEQRES  33 C 1008  PRO GLN PRO PHE LEU LYS HIS VAL LEU GLN LEU ILE PHE          
SEQRES  34 C 1008  ARG GLN GLN THR GLY LEU VAL ASP ALA ILE THR ARG CYS          
SEQRES  35 C 1008  TYR GLN PRO PHE GLU LEU PHE ASP ASN LYS THR ALA HIS          
SEQRES  36 C 1008  LEU SER ILE PRO GLY LYS SER THR PRO GLU GLY THR LEU          
SEQRES  37 C 1008  TRP ALA HIS VAL LEU LYS THR VAL ASP TYR GLY GLY ALA          
SEQRES  38 C 1008  GLU TRP SER LEU VAL ARG ILE TYR SER GLY LEU LEU LYS          
SEQRES  39 C 1008  ARG GLY ASP THR VAL ARG ILE LEU ASP THR SER GLN SER          
SEQRES  40 C 1008  GLU SER ARG GLN LYS ARG GLN LEU HIS ASP ILE SER LYS          
SEQRES  41 C 1008  THR GLU THR SER ASN GLU ASP GLU ASP GLU ASP ASP GLU          
SEQRES  42 C 1008  THR PRO SER CYS GLU VAL GLU GLU ILE GLY LEU LEU GLY          
SEQRES  43 C 1008  GLY ARG TYR VAL TYR PRO VAL HIS GLU ALA HIS LYS GLY          
SEQRES  44 C 1008  GLN ILE VAL LEU ILE LYS GLY ILE SER SER ALA TYR ILE          
SEQRES  45 C 1008  LYS SER ALA THR LEU TYR SER VAL LYS SER LYS GLU ASP          
SEQRES  46 C 1008  MET LYS GLN LEU LYS PHE PHE LYS PRO LEU ASP TYR ILE          
SEQRES  47 C 1008  THR GLU ALA VAL PHE LYS ILE VAL LEU GLN PRO LEU LEU          
SEQRES  48 C 1008  PRO ARG GLU LEU PRO LYS LEU LEU ASP ALA LEU ASN LYS          
SEQRES  49 C 1008  ILE SER LYS TYR TYR PRO GLY VAL ILE ILE LYS VAL GLU          
SEQRES  50 C 1008  GLU SER GLY GLU HIS VAL ILE LEU GLY ASN GLY GLU LEU          
SEQRES  51 C 1008  TYR MET ASP CYS LEU LEU TYR ASP LEU ARG ALA SER TYR          
SEQRES  52 C 1008  ALA LYS ILE GLU ILE LYS ILE SER ASP PRO LEU THR VAL          
SEQRES  53 C 1008  PHE SER GLU SER CYS SER ASN GLU SER PHE ALA SER ILE          
SEQRES  54 C 1008  PRO VAL SER ASN SER ILE SER ARG LEU GLY GLU GLU ASN          
SEQRES  55 C 1008  LEU PRO GLY LEU SER ILE SER VAL ALA ALA GLU PRO MET          
SEQRES  56 C 1008  ASP SER LYS MET ILE GLN ASP LEU SER ARG ASN THR LEU          
SEQRES  57 C 1008  GLY LYS GLY GLN ASN CYS LEU ASP ILE ASP GLY ILE MET          
SEQRES  58 C 1008  ASP ASN PRO ARG LYS LEU SER LYS ILE LEU ARG THR GLU          
SEQRES  59 C 1008  TYR GLY TRP ASP SER LEU ALA SER ARG ASN VAL TRP SER          
SEQRES  60 C 1008  PHE TYR ASN GLY ASN VAL LEU ILE ASN ASP THR LEU PRO          
SEQRES  61 C 1008  ASP GLU ILE SER PRO GLU LEU LEU SER LYS TYR LYS GLU          
SEQRES  62 C 1008  GLN ILE ILE GLN GLY PHE TYR TRP ALA VAL LYS GLU GLY          
SEQRES  63 C 1008  PRO LEU ALA GLU GLU PRO ILE TYR GLY VAL GLN TYR LYS          
SEQRES  64 C 1008  LEU LEU SER ILE SER VAL PRO SER ASP VAL ASN ILE ASP          
SEQRES  65 C 1008  VAL MET LYS SER GLN ILE ILE PRO LEU MET LYS LYS ALA          
SEQRES  66 C 1008  CYS TYR VAL GLY LEU LEU THR ALA ILE PRO ILE LEU LEU          
SEQRES  67 C 1008  GLU PRO ILE TYR GLU VAL ASP ILE THR VAL HIS ALA PRO          
SEQRES  68 C 1008  LEU LEU PRO ILE VAL GLU GLU LEU MET LYS LYS ARG ARG          
SEQRES  69 C 1008  GLY SER ARG ILE TYR LYS THR ILE LYS VAL ALA GLY THR          
SEQRES  70 C 1008  PRO LEU LEU GLU VAL ARG GLY GLN VAL PRO VAL ILE GLU          
SEQRES  71 C 1008  SER ALA GLY PHE GLU THR ASP LEU ARG LEU SER THR ASN          
SEQRES  72 C 1008  GLY LEU GLY MET CYS GLN LEU TYR PHE TRP HIS LYS ILE          
SEQRES  73 C 1008  TRP ARG LYS VAL PRO GLY ASP VAL LEU ASP LYS ASP ALA          
SEQRES  74 C 1008  PHE ILE PRO LYS LEU LYS PRO ALA PRO ILE ASN SER LEU          
SEQRES  75 C 1008  SER ARG ASP PHE VAL MET LYS THR ARG ARG ARG LYS GLY          
SEQRES  76 C 1008  ILE SER THR GLY GLY PHE MET SER ASN ASP GLY PRO THR          
SEQRES  77 C 1008  LEU GLU LYS TYR ILE SER ALA GLU LEU TYR ALA GLN LEU          
SEQRES  78 C 1008  ARG GLU ASN GLY LEU VAL PRO                                  
SEQRES   1 H  577  MET SER THR ALA THR ILE GLN ASP GLU ASP ILE LYS PHE          
SEQRES   2 H  577  GLN ARG GLU ASN TRP GLU MET ILE ARG SER HIS VAL SER          
SEQRES   3 H  577  PRO ILE ILE SER ASN LEU THR MET ASP ASN LEU GLN GLU          
SEQRES   4 H  577  SER HIS ARG ASP LEU PHE GLN VAL ASN ILE LEU ILE GLY          
SEQRES   5 H  577  ARG ASN ILE ILE CYS LYS ASN VAL VAL ASP PHE THR LEU          
SEQRES   6 H  577  ASN LYS GLN ASN GLY ARG LEU ILE PRO ALA LEU SER ALA          
SEQRES   7 H  577  LEU ILE ALA LEU LEU ASN SER ASP ILE PRO ASP ILE GLY          
SEQRES   8 H  577  GLU THR LEU ALA LYS GLU LEU MET LEU MET PHE VAL GLN          
SEQRES   9 H  577  GLN PHE ASN ARG LYS ASP TYR VAL SER CYS GLY ASN ILE          
SEQRES  10 H  577  LEU GLN CYS LEU SER ILE LEU PHE LEU TYR ASP VAL ILE          
SEQRES  11 H  577  HIS GLU ILE VAL ILE LEU GLN ILE LEU LEU LEU LEU LEU          
SEQRES  12 H  577  GLU LYS ASN SER LEU ARG LEU VAL ILE ALA VAL MET LYS          
SEQRES  13 H  577  ILE CYS GLY TRP LYS LEU ALA LEU VAL SER LYS LYS THR          
SEQRES  14 H  577  HIS ASP MET ILE TRP GLU LYS LEU ARG TYR ILE LEU GLN          
SEQRES  15 H  577  THR GLN GLU LEU SER SER THR LEU ARG GLU SER LEU GLU          
SEQRES  16 H  577  THR LEU PHE GLU ILE ARG GLN LYS ASP TYR LYS SER GLY          
SEQRES  17 H  577  SER GLN GLY LEU PHE ILE LEU ASP PRO THR SER TYR THR          
SEQRES  18 H  577  VAL HIS THR HIS SER TYR ILE VAL SER ASP GLU ASP GLU          
SEQRES  19 H  577  ALA ASN LYS GLU LEU GLY ASN PHE GLU LYS CYS GLU ASN          
SEQRES  20 H  577  PHE ASN GLU LEU THR MET ALA PHE ASP THR LEU ARG GLN          
SEQRES  21 H  577  LYS LEU LEU ILE ASN ASN THR SER ASP THR ASN GLU GLY          
SEQRES  22 H  577  SER ASN SER GLN LEU GLN ILE TYR ASP MET THR SER THR          
SEQRES  23 H  577  ASN ASP VAL GLU PHE LYS LYS LYS ILE TYR LEU VAL LEU          
SEQRES  24 H  577  LYS SER SER LEU SER GLY ASP GLU ALA ALA HIS LYS LEU          
SEQRES  25 H  577  LEU LYS LEU LYS ILE ALA ASN ASN LEU LYS LYS SER VAL          
SEQRES  26 H  577  VAL ASP ILE ILE ILE LYS SER SER LEU GLN GLU SER THR          
SEQRES  27 H  577  PHE SER LYS PHE TYR SER ILE LEU SER GLU ARG MET ILE          
SEQRES  28 H  577  THR PHE HIS ARG SER TRP GLN THR ALA TYR ASN GLU THR          
SEQRES  29 H  577  PHE GLU GLN ASN TYR THR GLN ASP ILE GLU ASP TYR GLU          
SEQRES  30 H  577  THR ASP GLN LEU ARG ILE LEU GLY LYS PHE TRP GLY HIS          
SEQRES  31 H  577  LEU ILE SER TYR GLU PHE LEU PRO MET ASP CYS LEU LYS          
SEQRES  32 H  577  ILE ILE LYS LEU THR GLU GLU GLU SER CYS PRO GLN GLY          
SEQRES  33 H  577  ARG ILE PHE ILE LYS PHE LEU PHE GLN GLU LEU VAL ASN          
SEQRES  34 H  577  GLU LEU GLY LEU ASP GLU LEU GLN LEU ARG LEU ASN SER          
SEQRES  35 H  577  SER LYS LEU ASP GLY MET PHE PRO LEU GLU GLY ASP ALA          
SEQRES  36 H  577  GLU HIS ILE ARG TYR SER ILE ASN PHE PHE THR ALA ILE          
SEQRES  37 H  577  GLY LEU GLY LEU LEU THR GLU ASP MET ARG SER ARG LEU          
SEQRES  38 H  577  THR ILE ILE GLN GLU VAL GLU ASP ALA GLU GLU GLU GLU          
SEQRES  39 H  577  LYS LYS LEU ARG GLU GLU GLU GLU LEU GLU LYS LEU ARG          
SEQRES  40 H  577  LYS LYS ALA ARG GLU SER GLN PRO THR GLN GLY PRO LYS          
SEQRES  41 H  577  ILE HIS GLU SER ARG LEU PHE LEU GLN LYS ASP THR ARG          
SEQRES  42 H  577  GLU ASN SER ARG SER ARG SER PRO PHE THR VAL GLU THR          
SEQRES  43 H  577  ARG LYS ARG ALA ARG SER ARG THR PRO PRO ARG GLY SER          
SEQRES  44 H  577  ARG ASN HIS ARG ASN ARG SER ARG THR PRO PRO ALA ARG          
SEQRES  45 H  577  ARG GLN ARG HIS ARG                                          
SEQRES   1 J  451  MET ASP GLY ASN ASP HIS LYS VAL GLU ASN LEU GLY ASP          
SEQRES   2 J  451  VAL ASP LYS PHE TYR SER ARG ILE ARG TRP ASN ASN GLN          
SEQRES   3 J  451  PHE SER TYR MET ALA THR LEU PRO PRO HIS LEU GLN SER          
SEQRES   4 J  451  GLU MET GLU GLY GLN LYS SER LEU LEU MET ARG TYR ASP          
SEQRES   5 J  451  THR TYR ARG LYS GLU SER SER SER PHE SER GLY GLU GLY          
SEQRES   6 J  451  LYS LYS VAL THR LEU GLN HIS VAL PRO THR ASP PHE SER          
SEQRES   7 J  451  GLU ALA SER GLN ALA VAL ILE SER LYS LYS ASP HIS ASP          
SEQRES   8 J  451  THR HIS ALA SER ALA PHE VAL ASN LYS ILE PHE GLN PRO          
SEQRES   9 J  451  GLU VAL ALA GLU GLU LEU ILE VAL ASN ARG TYR GLU LYS          
SEQRES  10 J  451  LEU LEU SER GLN ARG PRO GLU TRP HIS ALA PRO TRP LYS          
SEQRES  11 J  451  LEU SER ARG VAL ILE ASN GLY HIS LEU GLY TRP VAL ARG          
SEQRES  12 J  451  CYS VAL ALA ILE ASP PRO VAL ASP ASN GLU TRP PHE ILE          
SEQRES  13 J  451  THR GLY SER ASN ASP THR THR MET LYS VAL TRP ASP LEU          
SEQRES  14 J  451  ALA THR GLY LYS LEU LYS THR THR LEU ALA GLY HIS VAL          
SEQRES  15 J  451  MET THR VAL ARG ASP VAL ALA VAL SER ASP ARG HIS PRO          
SEQRES  16 J  451  TYR LEU PHE SER VAL SER GLU ASP LYS THR VAL LYS CYS          
SEQRES  17 J  451  TRP ASP LEU GLU LYS ASN GLN ILE ILE ARG ASP TYR TYR          
SEQRES  18 J  451  GLY HIS LEU SER GLY VAL ARG THR VAL SER ILE HIS PRO          
SEQRES  19 J  451  THR LEU ASP LEU ILE ALA THR ALA GLY ARG ASP SER VAL          
SEQRES  20 J  451  ILE LYS LEU TRP ASP MET ARG THR ARG ILE PRO VAL ILE          
SEQRES  21 J  451  THR LEU VAL GLY HIS LYS GLY PRO ILE ASN GLN VAL GLN          
SEQRES  22 J  451  CYS THR PRO VAL ASP PRO GLN VAL VAL SER SER SER THR          
SEQRES  23 J  451  ASP ALA THR VAL ARG LEU TRP ASP VAL VAL ALA GLY LYS          
SEQRES  24 J  451  THR MET LYS VAL LEU THR HIS HIS LYS ARG SER VAL ARG          
SEQRES  25 J  451  ALA THR ALA LEU HIS PRO LYS GLU PHE SER VAL ALA SER          
SEQRES  26 J  451  ALA CYS THR ASP ASP ILE ARG SER TRP GLY LEU ALA GLU          
SEQRES  27 J  451  GLY SER LEU LEU THR ASN PHE GLU SER GLU LYS THR GLY          
SEQRES  28 J  451  ILE ILE ASN THR LEU SER ILE ASN GLN ASP ASP VAL LEU          
SEQRES  29 J  451  PHE ALA GLY GLY ASP ASN GLY VAL LEU SER PHE TYR ASP          
SEQRES  30 J  451  TYR LYS SER GLY HIS LYS TYR GLN SER LEU ALA THR ARG          
SEQRES  31 J  451  GLU MET VAL GLY SER LEU GLU GLY GLU ARG SER VAL LEU          
SEQRES  32 J  451  CYS SER THR PHE ASP LYS THR GLY LEU ARG LEU ILE THR          
SEQRES  33 J  451  GLY GLU ALA ASP LYS SER ILE LYS ILE TRP LYS GLN ASP          
SEQRES  34 J  451  GLU THR ALA THR LYS GLU SER GLU PRO GLY LEU ALA TRP          
SEQRES  35 J  451  ASN PRO ASN LEU SER ALA LYS ARG PHE                          
SEQRES   1 K  379  MET PHE SER ASN ARG LEU PRO PRO PRO LYS HIS SER GLN          
SEQRES   2 K  379  GLY ARG VAL SER THR ALA LEU SER SER ASP ARG VAL GLU          
SEQRES   3 K  379  PRO ALA ILE LEU THR ASP GLN ILE ALA LYS ASN VAL LYS          
SEQRES   4 K  379  LEU ASP ASP PHE ILE PRO LYS ARG GLN SER ASN PHE GLU          
SEQRES   5 K  379  LEU SER VAL PRO LEU PRO THR LYS ALA GLU ILE GLN GLU          
SEQRES   6 K  379  CYS THR ALA ARG THR LYS SER TYR ILE GLN ARG LEU VAL          
SEQRES   7 K  379  ASN ALA LYS LEU ALA ASN SER ASN ASN ARG ALA SER SER          
SEQRES   8 K  379  ARG TYR VAL THR GLU THR HIS GLN ALA PRO ALA ASN LEU          
SEQRES   9 K  379  LEU LEU ASN ASN SER HIS HIS ILE GLU VAL VAL SER LYS          
SEQRES  10 K  379  GLN MET ASP PRO LEU LEU PRO ARG PHE VAL GLY LYS LYS          
SEQRES  11 K  379  ALA ARG LYS VAL VAL ALA PRO THR GLU ASN ASP GLU VAL          
SEQRES  12 K  379  VAL PRO VAL LEU HIS MET ASP GLY SER ASN ASP ARG GLY          
SEQRES  13 K  379  GLU ALA ASP PRO ASN GLU TRP LYS ILE PRO ALA ALA VAL          
SEQRES  14 K  379  SER ASN TRP LYS ASN PRO ASN GLY TYR THR VAL ALA LEU          
SEQRES  15 K  379  GLU ARG ARG VAL GLY LYS ALA LEU ASP ASN GLU ASN ASN          
SEQRES  16 K  379  THR ILE ASN ASP GLY PHE MET LYS LEU SER GLU ALA LEU          
SEQRES  17 K  379  GLU ASN ALA ASP LYS LYS ALA ARG GLN GLU ILE ARG SER          
SEQRES  18 K  379  LYS MET GLU LEU LYS ARG LEU ALA MET GLU GLN GLU MET          
SEQRES  19 K  379  LEU ALA LYS GLU SER LYS LEU LYS GLU LEU SER GLN ARG          
SEQRES  20 K  379  ALA ARG TYR HIS ASN GLY THR PRO GLN THR GLY ALA ILE          
SEQRES  21 K  379  VAL LYS PRO LYS LYS GLN THR SER THR VAL ALA ARG LEU          
SEQRES  22 K  379  LYS GLU LEU ALA TYR SER GLN GLY ARG ASP VAL SER GLU          
SEQRES  23 K  379  LYS ILE ILE LEU GLY ALA ALA LYS ARG SER GLU GLN PRO          
SEQRES  24 K  379  ASP LEU GLN TYR ASP SER ARG PHE PHE THR ARG GLY ALA          
SEQRES  25 K  379  ASN ALA SER ALA LYS ARG HIS GLU ASP GLN VAL TYR ASP          
SEQRES  26 K  379  ASN PRO LEU PHE VAL GLN GLN ASP ILE GLU SER ILE TYR          
SEQRES  27 K  379  LYS THR ASN TYR GLU LYS LEU ASP GLU ALA VAL ASN VAL          
SEQRES  28 K  379  LYS SER GLU GLY ALA SER GLY SER HIS GLY PRO ILE GLN          
SEQRES  29 K  379  PHE THR LYS ALA GLU SER ASP ASP LYS SER ASP ASN TYR          
SEQRES  30 K  379  GLY ALA                                                      
SEQRES   1 L  157  MET PRO ARG ILE LYS THR ARG ARG SER LYS PRO ALA PRO          
SEQRES   2 L  157  ASP GLY PHE GLU LYS ILE LYS PRO THR LEU THR ASP PHE          
SEQRES   3 L  157  GLU ILE GLN LEU ARG ASP ALA GLN LYS ASP LYS SER SER          
SEQRES   4 L  157  LYS LEU ALA ALA LYS SER ASN GLU GLN LEU TRP GLU ILE          
SEQRES   5 L  157  MET GLN LEU HIS HIS GLN ARG SER ARG TYR ILE TYR THR          
SEQRES   6 L  157  LEU TYR TYR LYS ARG LYS ALA ILE SER LYS ASP LEU TYR          
SEQRES   7 L  157  ASP TRP LEU ILE LYS GLU LYS TYR ALA ASP LYS LEU LEU          
SEQRES   8 L  157  ILE ALA LYS TRP ARG LYS THR GLY TYR GLU LYS LEU CYS          
SEQRES   9 L  157  CYS LEU ARG CYS ILE GLN LYS ASN GLU THR ASN ASN GLY          
SEQRES  10 L  157  SER THR CYS ILE CYS ARG VAL PRO ARG ALA GLN LEU GLU          
SEQRES  11 L  157  GLU GLU ALA ARG LYS LYS GLY THR GLN VAL SER PHE HIS          
SEQRES  12 L  157  GLN CYS VAL HIS CYS GLY CYS ARG GLY CYS ALA SER THR          
SEQRES  13 L  157  ASP                                                          
SEQRES   1 M  339  MET THR SER TRP ARG ASP LYS SER ALA LYS VAL GLN VAL          
SEQRES   2 M  339  LYS GLU SER GLU LEU PRO SER SER ILE PRO ALA GLN THR          
SEQRES   3 M  339  GLY LEU THR PHE ASN ILE TRP TYR ASN LYS TRP SER GLN          
SEQRES   4 M  339  GLY PHE ALA GLY ASN THR ARG PHE VAL SER PRO PHE ALA          
SEQRES   5 M  339  LEU GLN PRO GLN LEU HIS SER GLY LYS THR ARG GLY ASP          
SEQRES   6 M  339  ASN ASP GLY GLN LEU PHE PHE CYS LEU PHE PHE ALA LYS          
SEQRES   7 M  339  GLY MET CYS CYS LEU GLY PRO LYS CYS GLU TYR LEU HIS          
SEQRES   8 M  339  HIS ILE PRO ASP GLU GLU ASP ILE GLY LYS LEU ALA LEU          
SEQRES   9 M  339  ARG THR GLU VAL LEU ASP CYS PHE GLY ARG GLU LYS PHE          
SEQRES  10 M  339  ALA ASP TYR ARG GLU ASP MET GLY GLY ILE GLY SER PHE          
SEQRES  11 M  339  ARG LYS LYS ASN LYS THR LEU TYR VAL GLY GLY ILE ASP          
SEQRES  12 M  339  GLY ALA LEU ASN SER LYS HIS LEU LYS PRO ALA GLN ILE          
SEQRES  13 M  339  GLU SER ARG ILE ARG PHE VAL PHE SER ARG LEU GLY ASP          
SEQRES  14 M  339  ILE ASP ARG ILE ARG TYR VAL GLU SER LYS ASN CYS GLY          
SEQRES  15 M  339  PHE VAL LYS PHE LYS TYR GLN ALA ASN ALA GLU PHE ALA          
SEQRES  16 M  339  LYS GLU ALA MET SER ASN GLN THR LEU LEU LEU PRO SER          
SEQRES  17 M  339  ASP LYS GLU TRP ASP ASP ARG ARG GLU GLY THR GLY LEU          
SEQRES  18 M  339  LEU VAL LYS TRP ALA ASN GLU ASP PRO ASP PRO ALA ALA          
SEQRES  19 M  339  GLN LYS ARG LEU GLN GLU GLU LEU LYS LEU GLU SER LEU          
SEQRES  20 M  339  ASN MET MET VAL HIS LEU ILE ASN ASN ASN THR ASN SER          
SEQRES  21 M  339  ALA GLY THR GLU VAL ASN ASN LYS ASN ASN GLU ARG LEU          
SEQRES  22 M  339  ASP ARG THR PHE PRO GLU ALA SER VAL ASP ASN VAL LYS          
SEQRES  23 M  339  LYS ARG LEU LEU PRO LEU ASP ASN GLY MET GLU SER ASP          
SEQRES  24 M  339  ASP PHE ILE GLU LYS LEU LYS LYS VAL LYS LYS ASN ILE          
SEQRES  25 M  339  SER ARG GLU ASN ILE SER SER LYS PRO SER VAL GLY LYS          
SEQRES  26 M  339  LEU GLY GLY PRO LEU LEU ASP TYR LEU SER SER ASP GLU          
SEQRES  27 M  339  ASP                                                          
SEQRES   1 N  364  MET ASN ASP GLU ILE ASN GLU PRO PRO PRO ASN ILE CYS          
SEQRES   2 N  364  GLU GLN CYS LEU GLY ASP GLU ALA ASN ILE ARG MET THR          
SEQRES   3 N  364  LYS ILE PRO GLN GLY SER GLU CYS LYS ILE CYS THR LEU          
SEQRES   4 N  364  PRO PHE THR LEU TYR HIS PHE LYS THR SER LYS ARG SER          
SEQRES   5 N  364  ASN ASN ILE ILE LYS THR LEU ILE CYS VAL ARG CYS ALA          
SEQRES   6 N  364  THR GLN ARG ASN ILE CYS GLN CYS CYS MET LEU ASP SER          
SEQRES   7 N  364  ARG TRP HIS ILE PRO ILE GLN LEU ARG ASP HIS LEU ILE          
SEQRES   8 N  364  SER LEU VAL ASN GLU GLU ASN VAL MET THR GLU GLU ALA          
SEQRES   9 N  364  LYS ASN ASP MET MET LYS ARG PHE LEU SER LEU LYS ASN          
SEQRES  10 N  364  VAL LYS LEU GLY GLY ALA GLN ILE THR SER ASP PRO SER          
SEQRES  11 N  364  GLU ALA ASP ASN ILE VAL ASP LYS LEU LYS ASN ILE LEU          
SEQRES  12 N  364  LEU ARG ALA THR SER ASP GLY PRO SER THR PRO LEU ILE          
SEQRES  13 N  364  LYS ASN THR THR ALA LEU TYR LYS ASN GLU LYS GLY ALA          
SEQRES  14 N  364  ASN GLU VAL LYS ASN LEU GLU LYS TYR ALA SER VAL ASP          
SEQRES  15 N  364  ILE SER HIS ILE LEU LYS LYS LEU PRO LEU ASN GLU SER          
SEQRES  16 N  364  PHE LEU LYS ASN PRO SER THR LYS SER PHE PHE LEU TYR          
SEQRES  17 N  364  ASN ILE ASP ALA SER ILE PRO GLU TRP LYS ILE THR ASP          
SEQRES  18 N  364  THR VAL SER GLN LEU LEU GLY ILE LYS LYS TRP LYS ASP          
SEQRES  19 N  364  GLY ASN SER LEU SER LEU ILE VAL ASN HIS LYS ALA LYS          
SEQRES  20 N  364  CYS GLY GLY LEU ARG PHE GLN SER SER GLU LEU GLY GLU          
SEQRES  21 N  364  ARG PHE VAL SER LYS ILE SER GLU THR LEU VAL THR PRO          
SEQRES  22 N  364  LYS GLY LEU LYS ARG GLY VAL LEU LEU ILE ASP ARG PHE          
SEQRES  23 N  364  ARG ILE PHE ILE ILE PRO TRP SER SER GLY PHE SER ALA          
SEQRES  24 N  364  ALA SER PHE GLY THR ASN THR ALA GLU ASN ILE LYS LEU          
SEQRES  25 N  364  SER LEU SER LEU ASN LYS LEU ILE GLN LEU GLU LEU GLY          
SEQRES  26 N  364  LEU SER PHE PRO THR LYS SER THR ASP ASN ALA LYS ASN          
SEQRES  27 N  364  ASP LYS LYS LYS THR SER LYS LYS VAL HIS LYS ASP ARG          
SEQRES  28 N  364  SER LYS LYS SER LYS PRO ARG ALA ASN LYS LEU THR ILE          
SEQRES   1 O  590  MET PRO PRO VAL PRO ILE TYR VAL LYS GLY GLY VAL TRP          
SEQRES   2 O  590  THR ASN VAL GLU ASP GLN ILE LEU LYS ALA ALA VAL GLN          
SEQRES   3 O  590  LYS TYR GLY THR HIS GLN TRP SER LYS VAL ALA SER LEU          
SEQRES   4 O  590  LEU GLN LYS LYS THR ALA ARG GLN SER GLU LEU ARG TRP          
SEQRES   5 O  590  ASN GLU TYR LEU ASN PRO LYS LEU ASN PHE THR GLU PHE          
SEQRES   6 O  590  SER LYS GLU GLU ASP ALA GLN LEU LEU ASP LEU ALA ARG          
SEQRES   7 O  590  GLU LEU PRO ASN GLN TRP ARG THR ILE ALA ASP MET MET          
SEQRES   8 O  590  ALA ARG PRO ALA GLN VAL CYS VAL GLU ARG TYR ASN ARG          
SEQRES   9 O  590  LEU LEU GLU SER GLU ASP SER GLY GLY ALA ALA LEU SER          
SEQRES  10 O  590  THR GLY VAL THR ASP LEU LYS ALA GLY ASP ILE ASN PRO          
SEQRES  11 O  590  ASN ALA GLU THR GLN MET ALA ARG PRO ASP ASN GLY ASP          
SEQRES  12 O  590  LEU GLU ASP GLU GLU LYS GLU MET LEU ALA GLU ALA ARG          
SEQRES  13 O  590  ALA ARG LEU LEU ASN THR GLN GLY LYS LYS ALA THR ARG          
SEQRES  14 O  590  LYS ILE ARG GLU ARG MET LEU GLU GLU SER LYS ARG ILE          
SEQRES  15 O  590  ALA GLU LEU GLN LYS ARG ARG GLU LEU LYS GLN ALA GLY          
SEQRES  16 O  590  ILE ASN VAL ALA ILE LYS LYS PRO LYS LYS LYS TYR GLY          
SEQRES  17 O  590  THR ASP ILE ASP TYR ASN GLU ASP ILE VAL TYR GLU GLN          
SEQRES  18 O  590  ALA PRO MET PRO GLY ILE TYR ASP THR SER THR GLU ASP          
SEQRES  19 O  590  ARG GLN ILE LYS LYS LYS PHE GLU GLN PHE GLU ARG LYS          
SEQRES  20 O  590  VAL ASN ARG LYS GLY LEU ASP GLY ASN LYS ASP LYS PRO          
SEQRES  21 O  590  SER LYS LYS ASN LYS ASP LYS LYS ARG LYS HIS ASP GLU          
SEQRES  22 O  590  ASN GLU HIS VAL GLU LYS ALA ALA LEU GLY GLU SER THR          
SEQRES  23 O  590  THR LEU THR ASP GLU TYR LYS LYS PRO LYS LEU ILE LEU          
SEQRES  24 O  590  SER ALA PRO GLY THR LYS GLN GLY LYS VAL THR TYR LYS          
SEQRES  25 O  590  LYS LYS LEU GLU SER LYS ARG GLN LYS LEU ILE GLU ALA          
SEQRES  26 O  590  GLN ALA THR GLY THR VAL LEU THR PRO LYS GLU LEU LEU          
SEQRES  27 O  590  PRO HIS ASP SER GLY GLN GLU ASP ASN GLU ARG SER ASN          
SEQRES  28 O  590  ILE LYS SER GLY LYS GLN LEU LYS SER ARG ILE ARG LYS          
SEQRES  29 O  590  PHE LEU VAL GLN MET PHE ALA SER LEU PRO SER PRO LYS          
SEQRES  30 O  590  ASN ASP PHE GLU ILE VAL LEU SER GLU ASP GLU LYS GLU          
SEQRES  31 O  590  GLU ASP ALA GLU ILE ALA GLU TYR GLU LYS GLU PHE GLU          
SEQRES  32 O  590  ASN GLU ARG ALA MET ASN GLU GLU ASP ASN PHE ILE GLU          
SEQRES  33 O  590  PRO PRO SER GLN ASN ASP ALA PRO ARG VAL SER LEU VAL          
SEQRES  34 O  590  ALA VAL PRO LEU ALA TYR SER THR LEU PRO ILE PRO GLU          
SEQRES  35 O  590  PHE LYS ASN ASN PRO GLN SER ALA ILE ASP ASN LYS TYR          
SEQRES  36 O  590  ASN LEU LEU VAL ALA ASN ALA ILE ASN LYS GLU PRO HIS          
SEQRES  37 O  590  MET VAL PRO GLU ASP THR VAL ASP PHE LEU LYS GLU VAL          
SEQRES  38 O  590  GLU SER ARG MET GLN HIS ILE THR GLN GLY ARG THR SER          
SEQRES  39 O  590  MET LYS ILE GLN PHE LYS THR ALA MET PRO PRO THR GLU          
SEQRES  40 O  590  VAL LEU LEU GLU SER ILE GLN SER LYS VAL GLU SER ILE          
SEQRES  41 O  590  GLU GLN LEU GLN ARG LYS LEU GLN HIS VAL GLN PRO LEU          
SEQRES  42 O  590  GLU GLN GLN ASN ASN GLU MET CYS SER THR LEU CYS HIS          
SEQRES  43 O  590  HIS SER LEU PRO ALA LEU ILE GLU GLY GLN ARG LYS TYR          
SEQRES  44 O  590  TYR ALA ASP TYR TYR ALA TYR ARG GLN GLU ILE ARG SER          
SEQRES  45 O  590  LEU GLU GLY ARG ARG LYS ARG LEU GLN ALA MET LEU ASN          
SEQRES  46 O  590  SER SER SER SER ILE                                          
SEQRES   1 P  175  MET THR THR SER HIS ARG PRO GLN LEU GLU ALA ARG SER          
SEQRES   2 P  175  GLY ALA LYS ALA ALA ALA TYR THR PRO THR GLY ILE GLU          
SEQRES   3 P  175  HIS ALA ARG LEU LEU PRO GLY HIS THR THR LEU LYS TYR          
SEQRES   4 P  175  ARG LYS PHE LYS GLU GLU GLU ASN LEU ARG ALA ASN CYS          
SEQRES   5 P  175  ALA GLN GLU ASP ARG SER ASN ASP LYS SER LEU GLU GLU          
SEQRES   6 P  175  ALA VAL MET ASN GLU GLU LYS GLN ASP VAL VAL GLY SER          
SEQRES   7 P  175  GLY ASN LEU GLN GLU THR ARG SER GLU LYS ASP GLN LYS          
SEQRES   8 P  175  ASP SER LEU GLN GLU LEU LEU VAL THR GLN LYS ASN LYS          
SEQRES   9 P  175  VAL GLU ASP LYS ALA GLU LEU GLU GLY ASN GLU GLN LEU          
SEQRES  10 P  175  LYS GLY GLY ASN SER SER ARG ARG SER TRP ARG LYS GLY          
SEQRES  11 P  175  THR ALA PHE GLY ARG HIS LYS VAL THR LYS GLU THR ASN          
SEQRES  12 P  175  ILE LYS GLU HIS ALA THR LYS LYS SER ALA SER GLY TYR          
SEQRES  13 P  175  ILE ASN ASP MET THR LYS SER GLU TYR HIS GLN GLU PHE          
SEQRES  14 P  175  LEU HIS LYS HIS VAL ARG                                      
SEQRES   1 R  135  MET SER TYR ASN GLY ILE GLY LEU LYS SER ALA LYS GLY          
SEQRES   2 R  135  SER SER THR SER GLY HIS VAL GLN ARG SER LEU ALA SER          
SEQRES   3 R  135  ASN ASN ARG ARG ARG PRO GLN GLY SER GLN GLN GLN ARG          
SEQRES   4 R  135  GLN GLN ARG GLN ASN ALA ILE LYS LYS ALA SER HIS ASP          
SEQRES   5 R  135  LYS ALA SER ARG PRO LEU ALA VAL GLN LYS GLN ILE GLU          
SEQRES   6 R  135  THR HIS MET GLU LYS ARG GLU ILE GLU VAL GLN VAL SER          
SEQRES   7 R  135  GLU LEU ARG ASP ARG LEU GLU GLU GLU GLU THR LEU SER          
SEQRES   8 R  135  GLU GLU GLN ILE ASP LYS LYS CYS GLU ALA LEU ARG ALA          
SEQRES   9 R  135  LYS LEU THR ASN GLU TRP GLN GLU GLN GLN ARG MET SER          
SEQRES  10 R  135  SER LEU TYR THR PRO ARG LYS ALA ARG LEU THR GLU GLU          
SEQRES  11 R  135  GLN HIS ARG HIS GLU                                          
SEQRES   1 S  687  MET ASP THR LEU GLU PRO THR ALA VAL ASP THR HIS VAL          
SEQRES   2 S  687  SER ALA GLU GLN ILE LEU ARG ASP VAL TYR LYS LYS GLY          
SEQRES   3 S  687  GLN LYS ALA ARG GLY SER THR ASN ILE ASP ILE LEU ASP          
SEQRES   4 S  687  LEU GLU GLU LEU ARG GLU TYR GLN ARG ARG LYS ARG THR          
SEQRES   5 S  687  GLU TYR GLU GLY TYR LEU LYS ARG ASN ARG LEU ASP MET          
SEQRES   6 S  687  GLY GLN TRP ILE ARG TYR ALA GLN PHE GLU ILE GLU GLN          
SEQRES   7 S  687  HIS ASP MET ARG ARG ALA ARG SER ILE PHE GLU ARG ALA          
SEQRES   8 S  687  LEU LEU VAL ASP SER SER PHE ILE PRO LEU TRP ILE ARG          
SEQRES   9 S  687  TYR ILE ASP ALA GLU LEU LYS VAL LYS CYS ILE ASN HIS          
SEQRES  10 S  687  ALA ARG ASN LEU MET ASN ARG ALA ILE SER THR LEU PRO          
SEQRES  11 S  687  ARG VAL ASP LYS LEU TRP TYR LYS TYR LEU ILE VAL GLU          
SEQRES  12 S  687  GLU SER LEU ASN ASN VAL GLU ILE VAL ARG SER LEU TYR          
SEQRES  13 S  687  THR LYS TRP CYS SER LEU GLU PRO GLY VAL ASN ALA TRP          
SEQRES  14 S  687  ASN SER PHE VAL ASP PHE GLU ILE ARG GLN LYS ASN TRP          
SEQRES  15 S  687  ASN GLY VAL ARG GLU ILE TYR SER LYS TYR VAL MET ALA          
SEQRES  16 S  687  HIS PRO GLN MET GLN THR TRP LEU LYS TRP VAL ARG PHE          
SEQRES  17 S  687  GLU ASN ARG HIS GLY ASN THR GLU PHE THR ARG SER VAL          
SEQRES  18 S  687  TYR SER LEU ALA ILE ASP THR VAL ALA ASN LEU GLN ASN          
SEQRES  19 S  687  LEU GLN ILE TRP SER ASP MET GLU VAL ALA LYS LEU VAL          
SEQRES  20 S  687  ASN SER PHE ALA HIS TRP GLU ALA ALA GLN GLN GLU TYR          
SEQRES  21 S  687  GLU ARG SER SER ALA LEU TYR GLN ILE ALA ILE GLU LYS          
SEQRES  22 S  687  TRP PRO SER ASN GLN LEU LEU LYS ALA GLY LEU LEU ASP          
SEQRES  23 S  687  PHE GLU LYS GLN PHE GLY ASP ILE ASN SER ILE GLU GLU          
SEQRES  24 S  687  THR ILE SER TYR LYS ARG LYS MET GLU TYR GLU THR ILE          
SEQRES  25 S  687  LEU SER ASN ASN ALA TYR ASP TYR ASP THR TRP TRP LEU          
SEQRES  26 S  687  TYR LEU ASP LEU ILE SER GLU SER PHE PRO LYS GLN ILE          
SEQRES  27 S  687  MET GLN THR PHE GLU LYS ALA ILE VAL ASP SER ARG PRO          
SEQRES  28 S  687  LYS GLU LEU SER LYS ASN VAL GLN TRP LYS ARG TYR ILE          
SEQRES  29 S  687  TYR LEU TRP MET ARG TYR ILE CYS TYR VAL GLU LEU GLU          
SEQRES  30 S  687  LEU GLU ASN SER LEU LEU GLU GLU GLU LEU PHE GLN ARG          
SEQRES  31 S  687  LEU ILE ASP ASP ILE ILE PRO HIS LYS HIS PHE THR PHE          
SEQRES  32 S  687  SER LYS ILE TRP LEU MET TYR ALA LYS PHE LEU ILE ARG          
SEQRES  33 S  687  HIS ASP ASP VAL PRO LYS ALA ARG LYS ILE LEU GLY LYS          
SEQRES  34 S  687  ALA ILE GLY LEU CYS PRO LYS ALA LYS THR PHE LYS GLY          
SEQRES  35 S  687  TYR ILE GLU LEU GLU VAL LYS LEU LYS GLU PHE ASP ARG          
SEQRES  36 S  687  VAL ARG LYS ILE TYR GLU LYS PHE ILE GLU PHE GLN PRO          
SEQRES  37 S  687  SER ASP LEU GLN ILE TRP SER GLN TYR GLY GLU LEU GLU          
SEQRES  38 S  687  GLU ASN LEU GLY ASP TRP ASP ARG VAL ARG GLY ILE TYR          
SEQRES  39 S  687  THR ILE ALA LEU ASP GLU ASN SER ASP PHE LEU THR LYS          
SEQRES  40 S  687  GLU ALA LYS ILE VAL LEU LEU GLN LYS TYR ILE THR PHE          
SEQRES  41 S  687  GLU THR GLU SER GLN GLU PHE GLU LYS ALA ARG LYS LEU          
SEQRES  42 S  687  TYR ARG ARG TYR LEU GLU LEU ASN GLN TYR SER PRO GLN          
SEQRES  43 S  687  SER TRP ILE GLU PHE ALA MET TYR GLN THR SER THR PRO          
SEQRES  44 S  687  THR GLU GLN GLN LEU LEU ASP LEU ALA LYS LEU GLN SER          
SEQRES  45 S  687  GLU ASN VAL ASP GLU ASP ILE GLU PHE GLU ILE THR ASP          
SEQRES  46 S  687  GLU ASN LYS LEU GLU ALA ARG LYS VAL PHE GLU GLU ALA          
SEQRES  47 S  687  ILE VAL PHE PHE LYS GLU LYS ASP ASP LYS GLN GLY ARG          
SEQRES  48 S  687  LEU SER ILE LEU GLU ALA LEU LYS ASP TYR GLU GLU THR          
SEQRES  49 S  687  TYR GLY THR GLU LEU ASP GLN GLU THR VAL LYS LYS ARG          
SEQRES  50 S  687  PHE PRO LYS VAL ILE LYS LYS VAL ARG LEU GLN ASN GLY          
SEQRES  51 S  687  VAL GLU GLU GLU PHE VAL ASP TYR ILE PHE PRO ASP ASP          
SEQRES  52 S  687  ILE ASP ASP ASP LYS PRO LYS PRO SER LYS PHE LEU GLU          
SEQRES  53 S  687  LEU ALA LYS LYS TRP LYS GLN GLU GLN ALA LEU                  
SEQRES   1 T  877  MET SER ALA TYR ILE ALA MET LYS GLY VAL ILE THR ASN          
SEQRES   2 T  877  VAL ASP GLU ASN ILE ARG ASN ASP GLU ASP VAL ALA PHE          
SEQRES   3 T  877  GLU TYR GLU ILE GLN LYS THR PRO GLN ASN ILE LEU THR          
SEQRES   4 T  877  TRP LYS ARG TYR ILE GLU TYR TRP LYS GLU GLU GLY ARG          
SEQRES   5 T  877  THR ASP LYS GLN ILE ARG TRP LEU TYR GLU ARG PHE CYS          
SEQRES   6 T  877  SER GLN PHE VAL THR ASP THR SER ILE TRP GLU ASP TYR          
SEQRES   7 T  877  ILE ARG TRP GLU SER THR LYS GLU VAL VAL GLU THR SER          
SEQRES   8 T  877  ARG ILE PHE TRP LEU PHE GLN ARG CYS LEU LYS SER CYS          
SEQRES   9 T  877  VAL ARG ASP CYS ASP ARG ILE CYS LEU SER TYR LEU GLU          
SEQRES  10 T  877  LEU ALA ILE GLU GLN TYR ASP LEU ALA MET ILE ARG HIS          
SEQRES  11 T  877  ALA LEU ALA SER SER LEU MET LYS MET GLU ARG GLU MET          
SEQRES  12 T  877  HIS ARG LYS VAL TRP ASP PRO VAL ILE LYS PHE VAL GLU          
SEQRES  13 T  877  GLU LYS VAL LEU PRO LEU THR GLN LEU ASP SER THR GLN          
SEQRES  14 T  877  GLU ASP GLU GLU GLU SER THR ASP GLU ALA GLU LEU ILE          
SEQRES  15 T  877  ASN VAL LEU LEU VAL LYS GLY PHE THR LYS GLY GLY PHE          
SEQRES  16 T  877  ILE SER GLU GLU ILE SER GLU ASN GLY SER ARG GLY ASP          
SEQRES  17 T  877  ILE TRP SER SER HIS ILE LEU GLU ARG TYR LEU LYS VAL          
SEQRES  18 T  877  ALA PRO GLN GLN LYS ARG ASN GLU SER LEU ALA THR LEU          
SEQRES  19 T  877  ALA LEU THR ARG ASP ASN ILE THR ILE LYS SER VAL TYR          
SEQRES  20 T  877  GLU LYS TYR LEU PRO GLN ASP GLU ASN SER GLY LYS TYR          
SEQRES  21 T  877  LEU PRO SER SER GLU LEU PRO PHE GLU LEU ASN PHE ASN          
SEQRES  22 T  877  TYR LEU ALA SER LEU GLU LYS LEU GLY LEU ASP ASN GLN          
SEQRES  23 T  877  TYR GLU GLU PHE MET ARG GLN MET ASN GLY ILE TYR PRO          
SEQRES  24 T  877  ASP LYS TRP LEU PHE LEU ILE LEU SER LEU ALA LYS TYR          
SEQRES  25 T  877  TYR ILE SER ARG GLY ARG LEU ASP SER CYS GLY ASP LEU          
SEQRES  26 T  877  LEU LYS LYS SER LEU GLN GLN THR LEU ARG TYR SER ASP          
SEQRES  27 T  877  PHE ASP ARG ILE TYR ASN PHE TYR LEU LEU PHE GLU GLN          
SEQRES  28 T  877  GLU CYS SER GLN PHE ILE LEU GLY LYS LEU LYS GLU ASN          
SEQRES  29 T  877  ASP SER LYS PHE PHE ASN GLN LYS ASP TRP THR GLU LYS          
SEQRES  30 T  877  LEU GLN ALA HIS MET ALA THR PHE GLU SER LEU ILE ASN          
SEQRES  31 T  877  LEU TYR ASP ILE TYR LEU ASN ASP VAL ALA LEU ARG GLN          
SEQRES  32 T  877  ASP SER ASN LEU VAL GLU THR TRP MET LYS ARG VAL SER          
SEQRES  33 T  877  LEU GLN LYS SER ALA ALA GLU LYS CYS ASN VAL TYR SER          
SEQRES  34 T  877  GLU ALA ILE LEU LYS ILE ASP PRO ARG LYS VAL GLY THR          
SEQRES  35 T  877  PRO GLY SER PHE GLY ARG LEU TRP CYS SER TYR GLY ASP          
SEQRES  36 T  877  LEU TYR TRP ARG SER ASN ALA ILE SER THR ALA ARG GLU          
SEQRES  37 T  877  LEU TRP THR GLN SER LEU LYS VAL PRO TYR PRO TYR ILE          
SEQRES  38 T  877  GLU ASP LEU GLU GLU ILE TYR LEU ASN TRP ALA ASP ARG          
SEQRES  39 T  877  GLU LEU ASP LYS GLU GLY VAL GLU ARG ALA PHE SER ILE          
SEQRES  40 T  877  LEU GLU ASP ALA LEU HIS VAL PRO THR ASN PRO GLU ILE          
SEQRES  41 T  877  LEU LEU GLU LYS TYR LYS ASN GLY HIS ARG LYS ILE PRO          
SEQRES  42 T  877  ALA GLN THR VAL LEU PHE ASN SER LEU ARG ILE TRP SER          
SEQRES  43 T  877  LYS TYR ILE ASP TYR LEU GLU ALA TYR CYS PRO LYS ASP          
SEQRES  44 T  877  ALA ASN SER SER ASP LYS ILE PHE ASN LYS THR LYS MET          
SEQRES  45 T  877  ALA TYR ASN THR VAL ILE ASP LEU ARG LEU ILE THR PRO          
SEQRES  46 T  877  ALA MET ALA GLU ASN PHE ALA LEU PHE LEU GLN ASN HIS          
SEQRES  47 T  877  TYR GLU VAL MET GLU SER PHE GLN VAL TYR GLU LYS THR          
SEQRES  48 T  877  ILE PRO LEU PHE PRO PRO GLU ILE GLN TYR GLU LEU TRP          
SEQRES  49 T  877  ILE GLU TYR LEU GLU VAL ALA THR SER HIS GLN LEU SER          
SEQRES  50 T  877  SER LEU SER PRO GLU HIS ILE ARG PHE LEU PHE GLU LYS          
SEQRES  51 T  877  ALA LEU LYS ASN LEU CYS SER ASN GLY ILE ASP CYS LYS          
SEQRES  52 T  877  THR ILE PHE ILE ALA TYR SER VAL PHE GLU GLU ARG ILE          
SEQRES  53 T  877  SER GLY LEU ILE SER LYS SER ILE GLU ILE LEU ARG ARG          
SEQRES  54 T  877  GLY ALA VAL ILE GLY THR VAL SER VAL SER THR HIS LEU          
SEQRES  55 T  877  GLU SER ARG LEU GLN LEU TRP ARG MET CYS ILE SER LYS          
SEQRES  56 T  877  ALA GLU SER THR LEU GLY PRO SER VAL THR ARG GLU LEU          
SEQRES  57 T  877  TYR GLN GLU CYS ILE GLN ILE LEU PRO ASN SER LYS ALA          
SEQRES  58 T  877  VAL GLU PHE VAL ILE LYS PHE SER ASP PHE GLU SER SER          
SEQRES  59 T  877  ILE GLY GLU THR ILE ARG ALA ARG GLU ILE LEU ALA TYR          
SEQRES  60 T  877  GLY ALA LYS LEU LEU PRO PRO SER ARG ASN THR GLU LEU          
SEQRES  61 T  877  TRP ASP SER PHE GLU ILE PHE GLU LEU LYS HIS GLY ASP          
SEQRES  62 T  877  LYS GLU THR TYR LYS ASP MET LEU LYS MET LYS LYS VAL          
SEQRES  63 T  877  LEU GLU SER ASN MET LEU ILE ASP SER ALA SER VAL SER          
SEQRES  64 T  877  HIS GLU GLU GLY ASN ILE ASN PHE VAL ALA ALA ALA THR          
SEQRES  65 T  877  SER HIS ALA PRO ASN SER HIS THR LEU THR GLN SER THR          
SEQRES  66 T  877  SER SER TYR SER ILE ASN PRO ASP GLU ILE GLU LEU ASP          
SEQRES  67 T  877  ILE UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES  68 T  877  UNK UNK UNK UNK UNK UNK                                      
SEQRES   1 a  251  MET ASP LEU ASP LEU ALA SER ILE LEU LYS GLY GLU ILE          
SEQRES   2 a  251  SER LYS LYS LYS LYS GLU LEU ALA ASN SER LYS GLY VAL          
SEQRES   3 a  251  GLN PRO PRO CYS THR GLU LYS PHE GLN PRO HIS GLU SER          
SEQRES   4 a  251  ALA ASN ILE ASP GLU THR PRO ARG GLN VAL GLU GLN GLU          
SEQRES   5 a  251  SER THR ASP GLU GLU ASN LEU SER ASP ASN GLN SER ASP          
SEQRES   6 a  251  ASP ILE ARG THR THR ILE SER LYS LEU GLU ASN ARG PRO          
SEQRES   7 a  251  GLU ARG ILE GLN GLU ALA ILE ALA GLN ASP LYS THR ILE          
SEQRES   8 a  251  SER VAL ILE ILE ASP PRO SER GLN ILE GLY SER THR GLU          
SEQRES   9 a  251  GLY LYS PRO LEU LEU SER MET LYS CYS ASN LEU TYR ILE          
SEQRES  10 a  251  HIS GLU ILE LEU SER ARG TRP LYS ALA SER LEU GLU ALA          
SEQRES  11 a  251  TYR HIS PRO GLU LEU PHE LEU ASP THR LYS LYS ALA LEU          
SEQRES  12 a  251  PHE PRO LEU LEU LEU GLN LEU ARG ARG ASN GLN LEU ALA          
SEQRES  13 a  251  PRO ASP LEU LEU ILE SER LEU ALA THR VAL LEU TYR HIS          
SEQRES  14 a  251  LEU GLN GLN PRO LYS GLU ILE ASN LEU ALA VAL GLN SER          
SEQRES  15 a  251  TYR MET LYS LEU SER ILE GLY ASN VAL ALA TRP PRO ILE          
SEQRES  16 a  251  GLY VAL THR SER VAL GLY ILE HIS ALA ARG SER ALA HIS          
SEQRES  17 a  251  SER LYS ILE GLN GLY GLY ARG ASN ALA ALA ASN ILE MET          
SEQRES  18 a  251  ILE ASP GLU ARG THR ARG LEU TRP ILE THR SER ILE LYS          
SEQRES  19 a  251  ARG LEU ILE THR PHE GLU GLU TRP TYR THR SER ASN HIS          
SEQRES  20 a  251  ASP SER LEU ALA                                              
SEQRES   1 c  382  MET ASN ASN ASN SER ARG ASN ASN GLU ASN ARG SER THR          
SEQRES   2 c  382  ILE ASN ARG ASN LYS ARG GLN LEU GLN GLN ALA LYS GLU          
SEQRES   3 c  382  LYS ASN GLU ASN ILE HIS ILE PRO ARG TYR ILE ARG ASN          
SEQRES   4 c  382  GLN PRO TRP TYR TYR LYS ASP THR PRO LYS GLU GLN GLU          
SEQRES   5 c  382  GLY LYS LYS PRO GLY ASN ASP ASP THR SER THR ALA GLU          
SEQRES   6 c  382  GLY GLY GLU LYS SER ASP TYR LEU VAL HIS HIS ARG GLN          
SEQRES   7 c  382  LYS ALA LYS GLY GLY ALA LEU ASP ILE ASP ASN ASN SER          
SEQRES   8 c  382  GLU PRO LYS ILE GLY MET GLY ILE LYS ASP GLU PHE LYS          
SEQRES   9 c  382  LEU ILE ARG PRO GLN LYS MET SER VAL ARG ASP SER HIS          
SEQRES  10 c  382  SER LEU SER PHE CYS ARG ASN CYS GLY GLU ALA GLY HIS          
SEQRES  11 c  382  LYS GLU LYS ASP CYS MET GLU LYS PRO ARG LYS MET GLN          
SEQRES  12 c  382  LYS LEU VAL PRO ASP LEU ASN SER GLN LYS ASN ASN GLY          
SEQRES  13 c  382  THR VAL LEU VAL ARG ALA THR ASP ASP ASP TRP ASP SER          
SEQRES  14 c  382  ARG LYS ASP ARG TRP TYR GLY TYR SER GLY LYS GLU TYR          
SEQRES  15 c  382  ASN GLU LEU ILE SER LYS TRP GLU ARG ASP LYS ARG ASN          
SEQRES  16 c  382  LYS ILE LYS GLY LYS ASP LYS SER GLN THR ASP GLU THR          
SEQRES  17 c  382  LEU TRP ASP THR ASP GLU GLU ILE GLU LEU MET LYS LEU          
SEQRES  18 c  382  GLU LEU TYR LYS ASP SER VAL GLY SER LEU LYS LYS ASP          
SEQRES  19 c  382  ASP ALA ASP ASN SER GLN LEU TYR ARG THR SER THR ARG          
SEQRES  20 c  382  LEU ARG GLU ASP LYS ALA ALA TYR LEU ASN ASP ILE ASN          
SEQRES  21 c  382  SER THR GLU SER ASN TYR ASP PRO LYS SER ARG LEU TYR          
SEQRES  22 c  382  LYS THR GLU THR LEU GLY ALA VAL ASP GLU LYS SER LYS          
SEQRES  23 c  382  MET PHE ARG ARG HIS LEU THR GLY GLU GLY LEU LYS LEU          
SEQRES  24 c  382  ASN GLU LEU ASN GLN PHE ALA ARG SER HIS ALA LYS GLU          
SEQRES  25 c  382  MET GLY ILE ARG ASP GLU ILE GLU ASP LYS GLU LYS VAL          
SEQRES  26 c  382  GLN HIS VAL LEU VAL ALA ASN PRO THR LYS TYR GLU TYR          
SEQRES  27 c  382  LEU LYS LYS LYS ARG GLU GLN GLU GLU THR LYS GLN PRO          
SEQRES  28 c  382  LYS ILE VAL SER ILE GLY ASP LEU GLU ALA ARG LYS VAL          
SEQRES  29 c  382  ASP GLY THR LYS GLN SER GLU GLU GLN ARG ASN HIS LEU          
SEQRES  30 c  382  LYS ASP LEU TYR GLY                                          
SEQRES   1 o  455  MET GLY LEU VAL ASP GLY TYR ASP THR SER SER ASP SER          
SEQRES   2 o  455  ASP LEU ASN PHE ASP GLU GLY LYS SER VAL HIS GLU LYS          
SEQRES   3 o  455  LYS ASN GLY ASN LEU HIS GLU ASP THR SER TYR GLU PRO          
SEQRES   4 o  455  SER SER ASN ASN ILE HIS LYS ARG LYS SER HIS PHE THR          
SEQRES   5 o  455  LYS SER GLU LEU LYS ARG ARG ARG LYS THR ARG LYS GLY          
SEQRES   6 o  455  ASP GLY PRO TRP GLY SER TRP SER SER SER ASP ASP GLU          
SEQRES   7 o  455  THR SER GLN ALA SER GLU THR GLN LYS GLU ASP GLN ASP          
SEQRES   8 o  455  ILE PHE VAL HIS ALA LEU ALA GLU ASP ASN LEU ASP SER          
SEQRES   9 o  455  GLU GLN ILE GLU VAL GLU GLU VAL SER HIS PHE TYR GLY          
SEQRES  10 o  455  LYS SER GLU LYS ASP TYR GLN GLY ARG GLY TYR LEU TYR          
SEQRES  11 o  455  PRO PRO ASN ASP VAL ASP VAL ASP LEU ARG GLU GLU ARG          
SEQRES  12 o  455  ILE SER PHE ARG CYS TYR LEU PRO LYS LYS VAL ILE ARG          
SEQRES  13 o  455  ASN TYR PRO GLY HIS PRO GLU GLY THR THR ALA LEU LYS          
SEQRES  14 o  455  PHE LEU PRO LYS THR GLY HIS LEU ILE LEU SER GLY GLY          
SEQRES  15 o  455  ASN ASP HIS THR ILE LYS ILE TRP ASP PHE TYR HIS ASP          
SEQRES  16 o  455  TYR GLU CYS LEU ARG ASP PHE GLN GLY HIS ASN LYS PRO          
SEQRES  17 o  455  ILE LYS ALA LEU ARG PHE THR GLU ASP CYS GLN SER PHE          
SEQRES  18 o  455  LEU SER SER SER PHE ASP ARG SER VAL LYS ILE TRP ASP          
SEQRES  19 o  455  THR GLU THR GLY LYS VAL LYS THR ARG LEU HIS LEU ASN          
SEQRES  20 o  455  SER THR PRO ALA ASP VAL GLU SER ARG PRO THR ASN PRO          
SEQRES  21 o  455  HIS GLU PHE ILE VAL GLY LEU SER ASN SER LYS ILE LEU          
SEQRES  22 o  455  HIS TYR ASP ASP ARG VAL SER GLU ASN GLN GLY LEU VAL          
SEQRES  23 o  455  GLN THR TYR ASP HIS HIS LEU SER SER ILE LEU ALA LEU          
SEQRES  24 o  455  LYS TYR PHE PRO ASP GLY SER LYS PHE ILE SER SER SER          
SEQRES  25 o  455  GLU ASP LYS THR VAL ARG ILE TRP GLU ASN GLN ILE ASN          
SEQRES  26 o  455  VAL PRO ILE LYS GLN ILE SER ASP THR ALA GLN HIS SER          
SEQRES  27 o  455  MET PRO PHE LEU ASN VAL HIS PRO SER GLN ASN TYR PHE          
SEQRES  28 o  455  CYS ALA GLN SER MET ASP ASN ARG ILE TYR SER PHE SER          
SEQRES  29 o  455  LEU LYS PRO LYS TYR LYS ARG HIS PRO LYS LYS ILE PHE          
SEQRES  30 o  455  LYS GLY HIS SER SER ALA GLY TYR GLY ILE SER LEU ALA          
SEQRES  31 o  455  PHE SER GLY ASP GLY ARG TYR ILE CYS SER GLY ASP SER          
SEQRES  32 o  455  LYS SER ARG LEU PHE THR TRP ASP TRP ASN THR SER ARG          
SEQRES  33 o  455  LEU LEU ASN ASN ILE LYS ILE PRO GLY ASN LYS PRO ILE          
SEQRES  34 o  455  THR GLN VAL ASP TRP HIS PRO GLN GLU THR SER LYS VAL          
SEQRES  35 o  455  ILE CYS SER GLY ALA ALA GLY LYS ILE TYR VAL CYS ASP          
SEQRES   1 X   68  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   2 X   68  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   3 X   68  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   4 X   68  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   5 X   68  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   6 X   68  UNK UNK UNK                                                  
SEQRES   1 y  215  MET ASP PHE TYR LYS LEU ASP GLU LYS LEU LYS GLU LEU          
SEQRES   2 y  215  LYS ARG LYS ARG VAL ASP VAL SER ILE LYS SER ARG LYS          
SEQRES   3 y  215  LEU ALA ASP ARG GLU ILE GLN GLU VAL SER ALA ASN ARG          
SEQRES   4 y  215  LYS PRO ARG VAL TYR SER MET GLU ASP VAL ASN ASP ALA          
SEQRES   5 y  215  ASP GLU SER VAL GLY ASP THR GLU SER PRO GLU LYS GLU          
SEQRES   6 y  215  LYS ALA PHE HIS TYR THR VAL GLN GLU TYR ASP ALA TRP          
SEQRES   7 y  215  GLU ARG ARG HIS PRO GLN GLY LYS THR GLY GLN SER GLN          
SEQRES   8 y  215  ARG GLY GLY ILE SER TYR ASP GLN LEU ALA LYS LEU SER          
SEQRES   9 y  215  TYR GLU LYS THR LEU ARG ASN LEU ALA THR GLN THR GLN          
SEQRES  10 y  215  ASN SER SER LYS GLN ASP SER SER ALA ASP GLU GLU ASP          
SEQRES  11 y  215  ASN LYS ASN VAL PRO LYS LYS GLY ARG ILE GLY LYS VAL          
SEQRES  12 y  215  GLN LYS ASP THR LYS THR GLY LYS ILE THR ILE ALA ASP          
SEQRES  13 y  215  ASP ASP LYS LEU VAL ASN LYS LEU ALA VAL SER LEU GLN          
SEQRES  14 y  215  SER GLU SER LYS LYS ARG TYR GLU ALA ARG LYS ARG GLN          
SEQRES  15 y  215  MET GLN ASN ALA LYS THR LEU TYR GLY VAL GLU SER PHE          
SEQRES  16 y  215  ILE ASN ASP LYS ASN LYS GLN PHE ASN GLU LYS LEU SER          
SEQRES  17 y  215  ARG GLU SER LYS GLY SER GLU                                  
SEQRES   1 b  196  MET SER LYS ILE GLN VAL ALA HIS SER SER ARG LEU ALA          
SEQRES   2 b  196  ASN LEU ILE ASP TYR LYS LEU ARG VAL LEU THR GLN ASP          
SEQRES   3 b  196  GLY ARG VAL TYR ILE GLY GLN LEU MET ALA PHE ASP LYS          
SEQRES   4 b  196  HIS MET ASN LEU VAL LEU ASN GLU CYS ILE GLU GLU ARG          
SEQRES   5 b  196  VAL PRO LYS THR GLN LEU ASP LYS LEU ARG PRO ARG LYS          
SEQRES   6 b  196  ASP SER LYS ASP GLY THR THR LEU ASN ILE LYS VAL GLU          
SEQRES   7 b  196  LYS ARG VAL LEU GLY LEU THR ILE LEU ARG GLY GLU GLN          
SEQRES   8 b  196  ILE LEU SER THR VAL VAL GLU ASP LYS PRO LEU LEU SER          
SEQRES   9 b  196  LYS LYS GLU ARG LEU VAL ARG ASP LYS LYS GLU LYS LYS          
SEQRES  10 b  196  GLN ALA GLN LYS GLN THR LYS LEU ARG LYS GLU LYS GLU          
SEQRES  11 b  196  LYS LYS PRO GLY LYS ILE ALA LYS PRO ASN THR ALA ASN          
SEQRES  12 b  196  ALA LYS HIS THR SER SER ASN SER ARG GLU ILE ALA GLN          
SEQRES  13 b  196  PRO SER SER SER ARG TYR ASN GLY GLY ASN ASP ASN ILE          
SEQRES  14 b  196  GLY ALA ASN ARG SER ARG PHE ASN ASN GLU ALA PRO PRO          
SEQRES  15 b  196  GLN THR ARG LYS PHE GLN PRO PRO PRO GLY PHE LYS ARG          
SEQRES  16 b  196  LYS                                                          
SEQRES   1 d  101  MET THR MET ASN GLY ILE PRO VAL LYS LEU LEU ASN GLU          
SEQRES   2 d  101  ALA GLN GLY HIS ILE VAL SER LEU GLU LEU THR THR GLY          
SEQRES   3 d  101  ALA THR TYR ARG GLY LYS LEU VAL GLU SER GLU ASP SER          
SEQRES   4 d  101  MET ASN VAL GLN LEU ARG ASP VAL ILE ALA THR GLU PRO          
SEQRES   5 d  101  GLN GLY ALA VAL THR HIS MET ASP GLN ILE PHE VAL ARG          
SEQRES   6 d  101  GLY SER GLN ILE LYS PHE ILE VAL VAL PRO ASP LEU LEU          
SEQRES   7 d  101  LYS ASN ALA PRO LEU PHE LYS LYS ASN SER SER ARG PRO          
SEQRES   8 d  101  MET PRO PRO ILE ARG GLY PRO LYS ARG ARG                      
SEQRES   1 e   94  MET SER ASN LYS VAL LYS THR LYS ALA MET VAL PRO PRO          
SEQRES   2 e   94  ILE ASN CYS ILE PHE ASN PHE LEU GLN GLN GLN THR PRO          
SEQRES   3 e   94  VAL THR ILE TRP LEU PHE GLU GLN ILE GLY ILE ARG ILE          
SEQRES   4 e   94  LYS GLY LYS ILE VAL GLY PHE ASP GLU PHE MET ASN VAL          
SEQRES   5 e   94  VAL ILE ASP GLU ALA VAL GLU ILE PRO VAL ASN SER ALA          
SEQRES   6 e   94  ASP GLY LYS GLU ASP VAL GLU LYS GLY THR PRO LEU GLY          
SEQRES   7 e   94  LYS ILE LEU LEU LYS GLY ASP ASN ILE THR LEU ILE THR          
SEQRES   8 e   94  SER ALA ASP                                                  
SEQRES   1 f   86  MET SER GLU SER SER ASP ILE SER ALA MET GLN PRO VAL          
SEQRES   2 f   86  ASN PRO LYS PRO PHE LEU LYS GLY LEU VAL ASN HIS ARG          
SEQRES   3 f   86  VAL GLY VAL LYS LEU LYS PHE ASN SER THR GLU TYR ARG          
SEQRES   4 f   86  GLY THR LEU VAL SER THR ASP ASN TYR PHE ASN LEU GLN          
SEQRES   5 f   86  LEU ASN GLU ALA GLU GLU PHE VAL ALA GLY VAL SER HIS          
SEQRES   6 f   86  GLY THR LEU GLY GLU ILE PHE ILE ARG CYS ASN ASN VAL          
SEQRES   7 f   86  LEU TYR ILE ARG GLU LEU PRO ASN                              
SEQRES   1 g   77  MET VAL SER THR PRO GLU LEU LYS LYS TYR MET ASP LYS          
SEQRES   2 g   77  LYS ILE LEU LEU ASN ILE ASN GLY SER ARG LYS VAL ALA          
SEQRES   3 g   77  GLY ILE LEU ARG GLY TYR ASP ILE PHE LEU ASN VAL VAL          
SEQRES   4 g   77  LEU ASP ASP ALA MET GLU ILE ASN GLY GLU ASP PRO ALA          
SEQRES   5 g   77  ASN ASN HIS GLN LEU GLY LEU GLN THR VAL ILE ARG GLY          
SEQRES   6 g   77  ASN SER ILE ILE SER LEU GLU ALA LEU ASP ALA ILE              
SEQRES   1 h  146  MET LYS LEU VAL ASN PHE LEU LYS LYS LEU ARG ASN GLU          
SEQRES   2 h  146  GLN VAL THR ILE GLU LEU LYS ASN GLY THR THR VAL TRP          
SEQRES   3 h  146  GLY THR LEU GLN SER VAL SER PRO GLN MET ASN ALA ILE          
SEQRES   4 h  146  LEU THR ASP VAL LYS LEU THR LEU PRO GLN PRO ARG LEU          
SEQRES   5 h  146  ASN LYS LEU ASN SER ASN GLY ILE ALA MET ALA SER LEU          
SEQRES   6 h  146  TYR LEU THR GLY GLY GLN GLN PRO THR ALA SER ASP ASN          
SEQRES   7 h  146  ILE ALA SER LEU GLN TYR ILE ASN ILE ARG GLY ASN THR          
SEQRES   8 h  146  ILE ARG GLN ILE ILE LEU PRO ASP SER LEU ASN LEU ASP          
SEQRES   9 h  146  SER LEU LEU VAL ASP GLN LYS GLN LEU ASN SER LEU ARG          
SEQRES  10 h  146  ARG SER GLY GLN ILE ALA ASN ASP PRO SER LYS LYS ARG          
SEQRES  11 h  146  ARG ARG ASP PHE GLY ALA PRO ALA ASN LYS ARG PRO ARG          
SEQRES  12 h  146  ARG GLY LEU                                                  
SEQRES   1 j  110  MET SER SER GLN ILE ILE ASP ARG PRO LYS HIS GLU LEU          
SEQRES   2 j  110  SER ARG ALA GLU LEU GLU GLU LEU GLU GLU PHE GLU PHE          
SEQRES   3 j  110  LYS HIS GLY PRO MET SER LEU ILE ASN ASP ALA MET VAL          
SEQRES   4 j  110  THR ARG THR PRO VAL ILE ILE SER LEU ARG ASN ASN HIS          
SEQRES   5 j  110  LYS ILE ILE ALA ARG VAL LYS ALA PHE ASP ARG HIS CYS          
SEQRES   6 j  110  ASN MET VAL LEU GLU ASN VAL LYS GLU LEU TRP THR GLU          
SEQRES   7 j  110  LYS LYS GLY LYS ASN VAL ILE ASN ARG GLU ARG PHE ILE          
SEQRES   8 j  110  SER LYS LEU PHE LEU ARG GLY ASP SER VAL ILE VAL VAL          
SEQRES   9 j  110  LEU LYS THR PRO VAL GLU                                      
HET     MG  61001       1                                                       
HET     MG  61002       1                                                       
HET     MG  61003       1                                                       
HET      K  61004       1                                                       
HET      K  61005       1                                                       
HET    I6P  A3001      36                                                       
HET    GTP  C1101      32                                                       
HET     ZN  L1000       1                                                       
HET     ZN  L1001       1                                                       
HET     ZN  L1002       1                                                       
HET     ZN  M1000       1                                                       
HET     ZN  N 401       1                                                       
HET     ZN  N 402       1                                                       
HETNAM      MG MAGNESIUM ION                                                    
HETNAM       K POTASSIUM ION                                                    
HETNAM     I6P INOSITOL 1,2,3,4,5,6-HEXAKISPHOSPHATE                            
HETNAM     GTP GUANOSINE-5'-TRIPHOSPHATE                                        
HETNAM      ZN ZINC ION                                                         
HETSYN     I6P MYO-INOSITOL HEXAKISPHOSPHATE                                    
FORMUL  31   MG    3(MG 2+)                                                     
FORMUL  34    K    2(K 1+)                                                      
FORMUL  36  I6P    C6 H18 O24 P6                                                
FORMUL  37  GTP    C10 H16 N5 O14 P3                                            
FORMUL  38   ZN    6(ZN 2+)                                                     
HELIX    1 AA1 PRO A  135  HIS A  146  1                                  12    
HELIX    2 AA2 ASN A  155  LEU A  165  1                                  11    
HELIX    3 AA3 TYR A  167  ASN A  178  1                                  12    
HELIX    4 AA4 ILE A  209  ARG A  231  1                                  23    
HELIX    5 AA5 TYR A  275  TRP A  279  5                                   5    
HELIX    6 AA6 ASP A  304  SER A  315  1                                  12    
HELIX    7 AA7 ASP A  324  TYR A  328  5                                   5    
HELIX    8 AA8 ASP A  332  ASN A  343  1                                  12    
HELIX    9 AA9 ARG A  380  PHE A  387  1                                   8    
HELIX   10 AB1 PHE A  387  ASN A  392  1                                   6    
HELIX   11 AB2 ASN A  472  SER A  482  1                                  11    
HELIX   12 AB3 ALA A  502  GLN A  508  1                                   7    
HELIX   13 AB4 PRO A  515  HIS A  535  1                                  21    
HELIX   14 AB5 LYS A  546  THR A  554  1                                   9    
HELIX   15 AB6 TRP A  564  GLY A  587  1                                  24    
HELIX   16 AB7 THR A  606  ARG A  614  1                                   9    
HELIX   17 AB8 SER A  618  LEU A  641  1                                  24    
HELIX   18 AB9 ASP A  645  HIS A  659  1                                  15    
HELIX   19 AC1 HIS A  659  THR A  664  1                                   6    
HELIX   20 AC2 GLY A  665  LYS A  670  1                                   6    
HELIX   21 AC3 LYS A  672  ASN A  692  1                                  21    
HELIX   22 AC4 TRP A  704  GLU A  735  1                                  32    
HELIX   23 AC5 ARG A  749  MET A  770  1                                  22    
HELIX   24 AC6 ARG A  775  ASN A  796  1                                  22    
HELIX   25 AC7 PRO A  805  GLY A  837  1                                  33    
HELIX   26 AC8 GLU A  841  ASN A  870  1                                  30    
HELIX   27 AC9 THR A  875  SER A  894  1                                  20    
HELIX   28 AD1 ASN A  907  LYS A  926  1                                  20    
HELIX   29 AD2 ASN A  930  ASN A  946  1                                  17    
HELIX   30 AD3 ASN A  946  GLN A  961  1                                  16    
HELIX   31 AD4 ASP A  985  LYS A 1007  1                                  23    
HELIX   32 AD5 ILE A 1020  LEU A 1035  1                                  16    
HELIX   33 AD6 ASP A 1062  VAL A 1074  1                                  13    
HELIX   34 AD7 ASP A 1075  ASN A 1087  1                                  13    
HELIX   35 AD8 PHE A 1109  GLY A 1136  1                                  28    
HELIX   36 AD9 SER A 1149  HIS A 1156  1                                   8    
HELIX   37 AE1 GLU A 1175  ASN A 1190  1                                  16    
HELIX   38 AE2 ILE A 1216  VAL A 1234  1                                  19    
HELIX   39 AE3 LYS A 1242  GLU A 1244  5                                   3    
HELIX   40 AE4 SER A 1305  MET A 1321  1                                  17    
HELIX   41 AE5 THR A 1327  PHE A 1346  1                                  20    
HELIX   42 AE6 ARG A 1347  VAL A 1351  5                                   5    
HELIX   43 AE7 THR A 1353  LEU A 1375  1                                  23    
HELIX   44 AE8 PRO A 1385  THR A 1390  1                                   6    
HELIX   45 AE9 PRO A 1391  GLY A 1395  5                                   5    
HELIX   46 AF1 ASP A 1411  LYS A 1416  1                                   6    
HELIX   47 AF2 ILE A 1440  ILE A 1444  5                                   5    
HELIX   48 AF3 THR A 1446  ASN A 1472  1                                  27    
HELIX   49 AF4 GLY A 1482  ARG A 1486  5                                   5    
HELIX   50 AF5 ARG A 1490  PHE A 1495  5                                   6    
HELIX   51 AF6 ASP A 1498  ALA A 1503  1                                   6    
HELIX   52 AF7 GLY A 1507  LYS A 1515  1                                   9    
HELIX   53 AF8 ASN A 1529  GLY A 1534  1                                   6    
HELIX   54 AF9 LEU A 1539  LEU A 1550  1                                  12    
HELIX   55 AG1 GLY A 1551  THR A 1560  1                                  10    
HELIX   56 AG2 LEU A 1561  GLY A 1566  1                                   6    
HELIX   57 AG3 SER A 1569  PHE A 1574  5                                   6    
HELIX   58 AG4 ILE A 1601  TRP A 1610  1                                  10    
HELIX   59 AG5 TRP A 1610  ASN A 1615  1                                   6    
HELIX   60 AG6 ILE A 1638  PHE A 1649  1                                  12    
HELIX   61 AG7 HIS A 1652  GLU A 1672  1                                  21    
HELIX   62 AG8 HIS A 1687  TYR A 1692  5                                   6    
HELIX   63 AG9 ILE A 1748  THR A 1760  1                                  13    
HELIX   64 AH1 LEU A 1794  ALA A 1808  1                                  15    
HELIX   65 AH2 ASN A 1809  LEU A 1823  1                                  15    
HELIX   66 AH3 TYR A 1840  PHE A 1844  5                                   5    
HELIX   67 AH4 THR A 1896  GLY A 1901  1                                   6    
HELIX   68 AH5 ARG A 1904  LEU A 1924  1                                  21    
HELIX   69 AH6 MET A 1940  MET A 1948  1                                   9    
HELIX   70 AH7 LEU A 1949  PHE A 1951  5                                   3    
HELIX   71 AH8 SER A 1966  SER A 1970  5                                   5    
HELIX   72 AH9 ILE A 1971  ALA A 1981  1                                  11    
HELIX   73 AI1 ASP A 1993  ILE A 1999  1                                   7    
HELIX   74 AI2 SER A 2000  ASN A 2018  1                                  19    
HELIX   75 AI3 ASN A 2018  LEU A 2027  1                                  10    
HELIX   76 AI4 THR A 2044  TYR A 2067  1                                  24    
HELIX   77 AI5 LEU A 2074  LEU A 2084  1                                  11    
HELIX   78 AI6 ALA A 2090  GLU A 2100  1                                  11    
HELIX   79 AI7 ASN C  119  ALA C  127  1                                   9    
HELIX   80 AI8 GLY C  145  HIS C  158  1                                  14    
HELIX   81 AI9 SER C  165  GLY C  171  1                                   7    
HELIX   82 AJ1 LEU C  181  GLY C  188  1                                   8    
HELIX   83 AJ2 PHE C  221  SER C  232  1                                  12    
HELIX   84 AJ3 THR C  246  ASN C  259  1                                  14    
HELIX   85 AJ4 LYS C  269  ASP C  276  1                                   8    
HELIX   86 AJ5 PRO C  280  THR C  299  1                                  20    
HELIX   87 AJ6 THR C  323  TYR C  332  1                                  10    
HELIX   88 AJ7 LYS C  340  TRP C  349  1                                  10    
HELIX   89 AJ8 PRO C  371  ILE C  377  1                                   7    
HELIX   90 AJ9 ILE C  377  MET C  391  1                                  15    
HELIX   91 AK1 GLU C  392  ASN C  403  1                                  12    
HELIX   92 AK2 SER C  409  GLN C  414  1                                   6    
HELIX   93 AK3 ASP C  416  PHE C  429  1                                  14    
HELIX   94 AK4 THR C  433  TYR C  443  1                                  11    
HELIX   95 AK5 GLU C  447  SER C  457  1                                  11    
HELIX   96 AK6 SER C  462  GLY C  466  5                                   5    
HELIX   97 AK7 SER C  507  LEU C  515  1                                   9    
HELIX   98 AK8 ILE C  567  TYR C  571  5                                   5    
HELIX   99 AK9 SER C  582  LEU C  589  1                                   8    
HELIX  100 AL1 LEU C  611  ARG C  613  5                                   3    
HELIX  101 AL2 GLU C  614  TYR C  629  1                                  16    
HELIX  102 AL3 GLY C  648  SER C  662  1                                  15    
HELIX  103 AL4 ASP C  716  ARG C  725  1                                  10    
HELIX  104 AL5 ARG C  745  GLY C  756  1                                  12    
HELIX  105 AL6 SER C  759  VAL C  765  1                                   7    
HELIX  106 AL7 LYS C  792  GLU C  805  1                                  14    
HELIX  107 AL8 ASN C  830  ALA C  853  1                                  24    
HELIX  108 AL9 HIS C  869  PRO C  871  5                                   3    
HELIX  109 AM1 LEU C  872  ARG C  883  1                                  12    
HELIX  110 AM2 GLY C  913  THR C  922  1                                  10    
HELIX  111 AM3 SER C  961  GLY C  975  1                                  15    
HELIX  112 AM4 GLU C  990  LEU C  997  1                                   8    
HELIX  113 AM5 LYS H   12  LEU H   32  1                                  21    
HELIX  114 AM6 THR H   33  ASP H   35  5                                   3    
HELIX  115 AM7 ASN H   36  VAL H   47  1                                  12    
HELIX  116 AM8 GLY H   52  ASN H   66  1                                  15    
HELIX  117 AM9 ARG H   71  ILE H   87  1                                  17    
HELIX  118 AN1 ILE H   87  ARG H  108  1                                  22    
HELIX  119 AN2 ASP H  110  TYR H  127  1                                  18    
HELIX  120 AN3 ILE H  133  LYS H  145  1                                  13    
HELIX  121 AN4 VAL H  151  VAL H  165  1                                  15    
HELIX  122 AN5 SER H  166  THR H  183  1                                  18    
HELIX  123 AN6 SER H  187  ASP H  204  1                                  18    
HELIX  124 AN7 ASN H  247  LEU H  262  1                                  16    
HELIX  125 AN8 GLU H  290  SER H  302  1                                  13    
HELIX  126 AN9 SER H  304  LEU H  315  1                                  12    
HELIX  127 AO1 LEU H  321  GLU H  336  1                                  16    
HELIX  128 AO2 SER H  340  HIS H  354  1                                  15    
HELIX  129 AO3 HIS H  354  GLN H  371  1                                  18    
HELIX  130 AO4 ASP H  372  TYR H  376  5                                   5    
HELIX  131 AO5 GLU H  377  SER H  393  1                                  17    
HELIX  132 AO6 GLN H  415  LEU H  431  1                                  17    
HELIX  133 AO7 GLY H  432  SER H  443  1                                  12    
HELIX  134 AO8 HIS H  457  ILE H  468  1                                  12    
HELIX  135 AO9 LEU H  472  LEU H  481  1                                  10    
HELIX  136 AP1 ILE J  111  GLN J  121  1                                  11    
HELIX  137 AP2 LYS K   39  PHE K   43  5                                   5    
HELIX  138 AP3 THR K   59  SER K   85  1                                  27    
HELIX  139 AP4 ASN K   87  VAL K   94  5                                   8    
HELIX  140 AP5 ASN K  153  LYS K  164  1                                  12    
HELIX  141 AP6 ALA K  181  VAL K  186  1                                   6    
HELIX  142 AP7 GLY K  200  LEU K  225  1                                  26    
HELIX  143 AP8 GLY L   15  GLN L   34  1                                  20    
HELIX  144 AP9 ALA L   42  TYR L   68  1                                  27    
HELIX  145 AQ1 SER L   74  LYS L   85  1                                  12    
HELIX  146 AQ2 ASP L   88  LYS L   97  1                                  10    
HELIX  147 AQ3 CYS L  105  GLN L  110  5                                   6    
HELIX  148 AQ4 CYS L  120  VAL L  124  5                                   5    
HELIX  149 AQ5 PRO L  125  GLY L  137  1                                  13    
HELIX  150 AQ6 GLN M   54  SER M   59  1                                   6    
HELIX  151 AQ7 ARG M   63  GLY M   68  1                                   6    
HELIX  152 AQ8 CYS M   73  LYS M   78  1                                   6    
HELIX  153 AQ9 LEU M   83  CYS M   87  5                                   5    
HELIX  154 AR1 ASP M   95  ALA M  103  1                                   9    
HELIX  155 AR2 LEU M  104  VAL M  108  5                                   5    
HELIX  156 AR3 GLY M  141  LEU M  146  1                                   6    
HELIX  157 AR4 LYS M  152  ARG M  166  1                                  15    
HELIX  158 AR5 TYR M  188  MET M  199  1                                  12    
HELIX  159 AR6 ASP M  231  ILE M  254  1                                  24    
HELIX  160 AR7 CYS N   13  GLY N   18  1                                   6    
HELIX  161 AR8 CYS N   61  ASN N   69  1                                   9    
HELIX  162 AR9 PRO N   83  VAL N   94  1                                  12    
HELIX  163 AS1 ASN N  106  LYS N  116  1                                  11    
HELIX  164 AS2 GLY N  122  ASP N  128  1                                   7    
HELIX  165 AS3 ASP N  128  LEU N  144  1                                  17    
HELIX  166 AS4 PRO N  215  LEU N  226  1                                  12    
HELIX  167 AS5 SER N  255  ILE N  266  1                                  12    
HELIX  168 AS6 ALA N  307  LEU N  324  1                                  18    
HELIX  169 AS7 THR O   14  GLY O   29  1                                  16    
HELIX  170 AS8 GLN O   32  LEU O   40  1                                   9    
HELIX  171 AS9 THR O   44  TYR O   55  1                                  12    
HELIX  172 AT1 SER O   66  LEU O   80  1                                  15    
HELIX  173 AT2 GLN O   83  ALA O   92  1                                  10    
HELIX  174 AT3 PRO O   94  GLU O  107  1                                  14    
HELIX  175 AT4 GLU O  145  LEU O  160  1                                  16    
HELIX  176 AT5 GLY O  164  GLY O  195  1                                  32    
HELIX  177 AT6 THR O  230  LYS O  251  1                                  22    
HELIX  178 AT7 GLY P   14  TYR P   20  1                                   7    
HELIX  179 AT8 SER P  163  HIS P  173  1                                  11    
HELIX  180 AT9 SER R   10  SER R   15  1                                   6    
HELIX  181 AU1 ALA R   25  ARG R   31  1                                   7    
HELIX  182 AU2 GLN R   36  LYS R   47  1                                  12    
HELIX  183 AU3 ALA R   59  GLU R   87  1                                  29    
HELIX  184 AU4 SER R   91  MET R  116  1                                  26    
HELIX  185 AU5 ASP S   39  ASN S   61  1                                  23    
HELIX  186 AU6 ASP S   64  HIS S   79  1                                  16    
HELIX  187 AU7 ASP S   80  ASP S   95  1                                  16    
HELIX  188 AU8 PHE S   98  VAL S  112  1                                  15    
HELIX  189 AU9 CYS S  114  LEU S  129  1                                  16    
HELIX  190 AV1 VAL S  132  ASN S  147  1                                  16    
HELIX  191 AV2 ASN S  148  LEU S  162  1                                  15    
HELIX  192 AV3 GLY S  165  GLN S  179  1                                  15    
HELIX  193 AV4 GLY S  184  HIS S  196  1                                  13    
HELIX  194 AV5 GLN S  198  HIS S  212  1                                  15    
HELIX  195 AV6 ASN S  214  LEU S  232  1                                  19    
HELIX  196 AV7 SER S  239  GLN S  257  1                                  19    
HELIX  197 AV8 GLU S  259  TRP S  274  1                                  16    
HELIX  198 AV9 ASN S  277  PHE S  291  1                                  15    
HELIX  199 AW1 SER S  296  ASN S  315  1                                  20    
HELIX  200 AW2 ASP S  321  GLU S  332  1                                  12    
HELIX  201 AW3 PRO S  335  SER S  349  1                                  15    
HELIX  202 AW4 ASN S  357  GLU S  377  1                                  21    
HELIX  203 AW5 LEU S  382  ILE S  395  1                                  14    
HELIX  204 AW6 SER S  404  ARG S  416  1                                  13    
HELIX  205 AW7 VAL S  420  GLY S  432  1                                  13    
HELIX  206 AW8 PHE S  440  LEU S  450  1                                  11    
HELIX  207 AW9 PHE S  453  GLN S  467  1                                  15    
HELIX  208 AX1 LEU S  471  ASN S  483  1                                  13    
HELIX  209 AX2 ASP S  486  GLU S  500  1                                  15    
HELIX  210 AX3 GLU S  508  GLU S  521  1                                  14    
HELIX  211 AX4 ARG S  531  ASN S  541  1                                  11    
HELIX  212 AX5 GLN S  546  THR S  556  1                                  11    
HELIX  213 AX6 VAL T  408  LYS T  419  1                                  12    
HELIX  214 AX7 LYS T  424  ILE T  435  1                                  12    
HELIX  215 AX8 LEU T  449  ASN T  461  1                                  13    
HELIX  216 AX9 ALA T  462  LYS T  475  1                                  14    
HELIX  217 AY1 LEU T  484  ASP T  497  1                                  14    
HELIX  218 AY2 GLU T  502  GLU T  523  1                                  22    
HELIX  219 AY3 LEU T  542  TYR T  555  1                                  14    
HELIX  220 AY4 PHE T  567  ARG T  581  1                                  15    
HELIX  221 AY5 ALA T  586  ASN T  597  1                                  12    
HELIX  222 AY6 MET T  602  ILE T  612  1                                  11    
HELIX  223 AY7 GLU T  618  HIS T  634  1                                  17    
HELIX  224 AY8 GLU T  642  LEU T  655  1                                  14    
HELIX  225 AY9 ASP T  661  SER T  677  1                                  17    
HELIX  226 AZ1 SER T  681  ILE T  693  1                                  13    
HELIX  227 AZ2 GLU T  703  THR T  719  1                                  17    
HELIX  228 AZ3 VAL T  724  ILE T  735  1                                  12    
HELIX  229 AZ4 LYS T  740  ILE T  755  1                                  16    
HELIX  230 AZ5 ILE T  759  LEU T  771  1                                  13    
HELIX  231 AZ6 THR T  778  LYS T  790  1                                  13    
HELIX  232 AZ7 UNK T 1001  UNK T 1017  1                                  17    
HELIX  233 AZ8 ARG a   77  LYS a   89  1                                  13    
HELIX  234 AZ9 PRO a  107  SER a  127  1                                  21    
HELIX  235 BA1 PRO a  133  ARG a  151  1                                  19    
HELIX  236 BA2 ALA a  156  GLN a  172  1                                  17    
HELIX  237 BA3 GLU a  175  ILE a  188  1                                  14    
HELIX  238 BA4 GLU a  224  ASN a  246  1                                  23    
HELIX  239 BA5 TRP c  167  ASP c  172  1                                   6    
HELIX  240 BA6 GLY c  179  LYS c  196  1                                  18    
HELIX  241 BA7 GLU c  217  TYR c  224  1                                   8    
HELIX  242 BA8 GLY c  294  MET c  313  1                                  20    
HELIX  243 BA9 LYS c  324  LEU c  329  1                                   6    
HELIX  244 BB1 THR c  334  THR c  348  1                                  15    
HELIX  245 BB2 THR o   52  ARG o   60  1                                   9    
HELIX  246 BB3 ASP o  276  GLN o  283  1                                   8    
HELIX  247 BB4 UNK X    6  UNK X   15  1                                  10    
HELIX  248 BB5 UNK X   16  UNK X   26  1                                  11    
HELIX  249 BB6 UNK X   92  UNK X  129  1                                  38    
HELIX  250 BB7 SER y   96  THR y  114  1                                  19    
HELIX  251 BB8 ASP y  157  GLN y  184  1                                  28    
HELIX  252 BB9 ASN y  197  ARG y  209  1                                  13    
HELIX  253 BC1 LEU b   12  ILE b   16  5                                   5    
HELIX  254 BC2 GLY d    5  ALA d   14  1                                  10    
HELIX  255 BC3 PRO e   12  GLN e   24  1                                  13    
HELIX  256 BC4 GLY e   84  ILE e   87  5                                   4    
HELIX  257 BC5 ASN f   14  LEU f   22  1                                   9    
HELIX  258 BC6 LYS h    2  LEU h   10  1                                   9    
HELIX  259 BC7 ASN h  102  VAL h  108  1                                   7    
HELIX  260 BC8 ALA j   16  GLY j   29  1                                  14    
HELIX  261 BC9 MET j   31  ARG j   41  1                                  11    
SHEET    1 AA1 2 GLU A 188  HIS A 194  0                                        
SHEET    2 AA1 2 PHE A 557  ASP A 563 -1  O  ILE A 562   N  VAL A 189           
SHEET    1 AA2 2 ARG A 207  VAL A 208  0                                        
SHEET    2 AA2 2 VAL A 494  ARG A 495 -1  O  VAL A 494   N  VAL A 208           
SHEET    1 AA3 2 LYS A 300  TRP A 301  0                                        
SHEET    2 AA3 2 GLY A 491  LYS A 492 -1  O  GLY A 491   N  TRP A 301           
SHEET    1 AA4 2 LEU A 591  LEU A 593  0                                        
SHEET    2 AA4 2 LEU A 599  PRO A 601 -1  O  LYS A 600   N  HIS A 592           
SHEET    1 AA5 2 ASP A 968  MET A 972  0                                        
SHEET    2 AA5 2 SER A 979  SER A 983 -1  O  SER A 983   N  ASP A 968           
SHEET    1 AA6 4 ILE A1158  LEU A1160  0                                        
SHEET    2 AA6 4 ARG A1167  PHE A1174 -1  O  LEU A1171   N  LEU A1160           
SHEET    3 AA6 4 SER A1046  THR A1053 -1  N  VAL A1048   O  PHE A1172           
SHEET    4 AA6 4 ALA A1246  TYR A1251 -1  O  TYR A1251   N  ALA A1047           
SHEET    1 AA7 4 LEU A1258  MET A1262  0                                        
SHEET    2 AA7 4 PHE A1265  PRO A1271 -1  O  VAL A1267   N  PHE A1260           
SHEET    3 AA7 4 ALA A1298  VAL A1304 -1  O  LYS A1299   N  LEU A1270           
SHEET    4 AA7 4 VAL A1285  LEU A1288 -1  N  LEU A1288   O  ALA A1298           
SHEET    1 AA8 3 LEU A1406  PRO A1408  0                                        
SHEET    2 AA8 3 HIS A1424  ALA A1427 -1  O  ARG A1426   N  ILE A1407           
SHEET    3 AA8 3 VAL R  20  ARG R  22 -1  O  GLN R  21   N  PHE A1425           
SHEET    1 AA9 2 LEU A1624  GLN A1626  0                                        
SHEET    2 AA9 2 PHE A1633  HIS A1635 -1  O  LEU A1634   N  VAL A1625           
SHEET    1 AB1 6 ILE A1678  LYS A1683  0                                        
SHEET    2 AB1 6 ILE A1701  SER A1705 -1  O  THR A1702   N  THR A1682           
SHEET    3 AB1 6 LYS A1731  ASP A1735 -1  O  PHE A1734   N  ILE A1701           
SHEET    4 AB1 6 VAL A1773  ASP A1778  1  O  ILE A1775   N  ASP A1735           
SHEET    5 AB1 6 MET A1783  GLY A1788 -1  O  ASP A1785   N  GLY A1776           
SHEET    6 AB1 6 SER A1715  LEU A1716 -1  N  SER A1715   O  GLY A1788           
SHEET    1 AB2 6 ALA A1955  PRO A1958  0                                        
SHEET    2 AB2 6 GLN A1932  VAL A1935  1  N  ILE A1933   O  ALA A1955           
SHEET    3 AB2 6 LYS A1849  ASP A1853  1  N  VAL A1852   O  ILE A1934           
SHEET    4 AB2 6 PHE A1880  LEU A1882 -1  O  PHE A1880   N  ASP A1853           
SHEET    5 AB2 6 HIS A1888  ILE A1893 -1  O  PHE A1890   N  THR A1881           
SHEET    6 AB2 6 GLN A1985  MET A1986 -1  O  GLN A1985   N  ILE A1893           
SHEET    1 AB3 6 ALA A1955  PRO A1958  0                                        
SHEET    2 AB3 6 GLN A1932  VAL A1935  1  N  ILE A1933   O  ALA A1955           
SHEET    3 AB3 6 LYS A1849  ASP A1853  1  N  VAL A1852   O  ILE A1934           
SHEET    4 AB3 6 PHE A1880  LEU A1882 -1  O  PHE A1880   N  ASP A1853           
SHEET    5 AB3 6 HIS A1888  ILE A1893 -1  O  PHE A1890   N  THR A1881           
SHEET    6 AB3 6 PHE A1989  ASN A1990 -1  O  PHE A1989   N  LEU A1889           
SHEET    1 AB4 2 ARG A1859  LYS A1864  0                                        
SHEET    2 AB4 2 VAL A1870  ILE A1875 -1  O  LYS A1873   N  THR A1861           
SHEET    1 AB5 5 GLU C  79  LYS C  81  0                                        
SHEET    2 AB5 5 TRP J 129  ILE J 135  1  O  VAL J 134   N  GLU C  79           
SHEET    3 AB5 5 ILE J 423  GLN J 428 -1  O  ILE J 425   N  ARG J 133           
SHEET    4 AB5 5 ARG J 413  GLU J 418 -1  N  THR J 416   O  LYS J 424           
SHEET    5 AB5 5 VAL J 402  PHE J 407 -1  N  THR J 406   O  ILE J 415           
SHEET    1 AB6 3 ILE C 133  ASN C 135  0                                        
SHEET    2 AB6 3 SER C 207  PHE C 212  1  O  ASN C 211   N  ILE C 134           
SHEET    3 AB6 3 SER C 196  THR C 201 -1  N  LEU C 198   O  ILE C 210           
SHEET    1 AB7 2 LEU C 234  VAL C 235  0                                        
SHEET    2 AB7 2 ALA C 262  MET C 263  1  O  ALA C 262   N  VAL C 235           
SHEET    1 AB8 4 VAL C 238  ASP C 240  0                                        
SHEET    2 AB8 4 VAL C 266  ASN C 268  1  O  ASN C 268   N  ILE C 239           
SHEET    3 AB8 4 ILE C 312  SER C 315  1  O  ALA C 314   N  ILE C 267           
SHEET    4 AB8 4 PHE C 320  PHE C 322 -1  O  PHE C 322   N  PHE C 313           
SHEET    1 AB9 8 CYS C 537  GLU C 538  0                                        
SHEET    2 AB9 8 THR C 498  ASP C 503 -1  N  VAL C 499   O  CYS C 537           
SHEET    3 AB9 8 ALA C 575  SER C 579 -1  O  TYR C 578   N  ARG C 500           
SHEET    4 AB9 8 LEU C 468  VAL C 476 -1  N  ALA C 470   O  LEU C 577           
SHEET    5 AB9 8 TRP C 483  SER C 490 -1  O  ARG C 487   N  HIS C 471           
SHEET    6 AB9 8 GLN C 560  ILE C 564 -1  O  VAL C 562   N  VAL C 486           
SHEET    7 AB9 8 ILE C 542  LEU C 545 -1  N  GLY C 543   O  LEU C 563           
SHEET    8 AB9 8 VAL C 550  PRO C 552 -1  O  TYR C 551   N  LEU C 544           
SHEET    1 AC1 2 LEU C 492  LYS C 494  0                                        
SHEET    2 AC1 2 GLU C 555  HIS C 557 -1  O  ALA C 556   N  LEU C 493           
SHEET    1 AC2 3 HIS C 642  GLY C 646  0                                        
SHEET    2 AC2 3 PHE C 603  PRO C 609 -1  N  ILE C 605   O  ILE C 644           
SHEET    3 AC2 3 ILE C 668  ILE C 670 -1  O  LYS C 669   N  GLN C 608           
SHEET    1 AC3 3 SER C 678  CYS C 681  0                                        
SHEET    2 AC3 3 PRO C 855  GLU C 859 -1  O  LEU C 858   N  SER C 678           
SHEET    3 AC3 3 ARG C 938  LYS C 939 -1  O  ARG C 938   N  GLU C 859           
SHEET    1 AC4 3 SER C 709  PRO C 714  0                                        
SHEET    2 AC4 3 VAL C 816  SER C 822 -1  O  GLN C 817   N  GLU C 713           
SHEET    3 AC4 3 ILE C 775  ASP C 777  1  N  ASP C 777   O  LEU C 820           
SHEET    1 AC5 4 ARG C 887  LYS C 890  0                                        
SHEET    2 AC5 4 VAL C 902  PRO C 907 -1  O  GLN C 905   N  ARG C 887           
SHEET    3 AC5 4 ILE C 861  ILE C 866 -1  N  ILE C 866   O  VAL C 902           
SHEET    4 AC5 4 CYS C 928  TYR C 931 -1  O  TYR C 931   N  GLU C 863           
SHEET    1 AC6 4 CYS J 144  ILE J 147  0                                        
SHEET    2 AC6 4 TRP J 154  GLY J 158 -1  O  ILE J 156   N  ALA J 146           
SHEET    3 AC6 4 MET J 164  ASP J 168 -1  O  TRP J 167   N  PHE J 155           
SHEET    4 AC6 4 LEU J 174  LEU J 178 -1  O  THR J 176   N  VAL J 166           
SHEET    1 AC7 4 VAL J 185  VAL J 190  0                                        
SHEET    2 AC7 4 TYR J 196  SER J 201 -1  O  PHE J 198   N  ALA J 189           
SHEET    3 AC7 4 LYS J 207  ASP J 210 -1  O  TRP J 209   N  LEU J 197           
SHEET    4 AC7 4 ILE J 216  ASP J 219 -1  O  ILE J 217   N  CYS J 208           
SHEET    1 AC8 4 VAL J 227  ILE J 232  0                                        
SHEET    2 AC8 4 LEU J 238  GLY J 243 -1  O  ALA J 240   N  SER J 231           
SHEET    3 AC8 4 ILE J 248  ASP J 252 -1  O  TRP J 251   N  ILE J 239           
SHEET    4 AC8 4 ILE J 257  LEU J 262 -1  O  LEU J 262   N  ILE J 248           
SHEET    1 AC9 4 GLN J 271  CYS J 274  0                                        
SHEET    2 AC9 4 PRO J 279  SER J 284 -1  O  SER J 284   N  GLN J 271           
SHEET    3 AC9 4 VAL J 290  ASP J 294 -1  O  ARG J 291   N  SER J 283           
SHEET    4 AC9 4 LYS J 299  LEU J 304 -1  O  LYS J 299   N  ASP J 294           
SHEET    1 AD1 4 THR J 314  LEU J 316  0                                        
SHEET    2 AD1 4 VAL J 323  SER J 325 -1  O  ALA J 324   N  ALA J 315           
SHEET    3 AD1 4 SER J 333  GLY J 335 -1  O  TRP J 334   N  VAL J 323           
SHEET    4 AD1 4 SER J 340  THR J 343 -1  O  THR J 343   N  SER J 333           
SHEET    1 AD2 3 PHE J 365  GLY J 367  0                                        
SHEET    2 AD2 3 LEU J 373  TYR J 376 -1  O  SER J 374   N  ALA J 366           
SHEET    3 AD2 3 LYS J 383  LEU J 387 -1  O  LEU J 387   N  LEU J 373           
SHEET    1 AD3 4 HIS K 111  VAL K 115  0                                        
SHEET    2 AD3 4 ASN N  22  ILE N  28  1  O  LYS N  27   N  VAL K 115           
SHEET    3 AD3 4 LEU N  43  LYS N  47 -1  O  HIS N  45   N  THR N  26           
SHEET    4 AD3 4 ILE N  55  LYS N  57 -1  O  ILE N  56   N  PHE N  46           
SHEET    1 AD4 2 THR M  29  PHE M  30  0                                        
SHEET    2 AD4 2 TRP M  37  SER M  38 -1  O  SER M  38   N  THR M  29           
SHEET    1 AD5 4 ILE M 170  ILE M 173  0                                        
SHEET    2 AD5 4 GLY M 182  PHE M 186 -1  O  LYS M 185   N  ASP M 171           
SHEET    3 AD5 4 THR M 136  GLY M 140 -1  N  LEU M 137   O  VAL M 184           
SHEET    4 AD5 4 LEU M 222  TRP M 225 -1  O  LYS M 224   N  TYR M 138           
SHEET    1 AD6 4 ARG o 156  TYR o 158  0                                        
SHEET    2 AD6 4 LYS o 450  VAL o 453 -1  O  VAL o 453   N  ARG o 156           
SHEET    3 AD6 4 VAL o 442  GLY o 446 -1  N  CYS o 444   O  TYR o 452           
SHEET    4 AD6 4 ASP o 433  TRP o 434 -1  N  ASP o 433   O  ILE o 443           
SHEET    1 AD7 3 LYS o 169  PHE o 170  0                                        
SHEET    2 AD7 3 LEU o 177  LEU o 179 -1  O  LEU o 179   N  LYS o 169           
SHEET    3 AD7 3 ILE o 189  ASP o 191 -1  O  TRP o 190   N  ILE o 178           
SHEET    1 AD8 4 ILE o 209  PHE o 214  0                                        
SHEET    2 AD8 4 SER o 220  SER o 225 -1  O  SER o 224   N  LYS o 210           
SHEET    3 AD8 4 VAL o 230  ASP o 234 -1  O  TRP o 233   N  PHE o 221           
SHEET    4 AD8 4 THR o 242  ARG o 243 -1  O  ARG o 243   N  VAL o 230           
SHEET    1 AD9 3 ASP o 252  SER o 255  0                                        
SHEET    2 AD9 3 PHE o 263  GLY o 266 -1  O  ILE o 264   N  GLU o 254           
SHEET    3 AD9 3 ILE o 272  LEU o 273 -1  O  LEU o 273   N  VAL o 265           
SHEET    1 AE1 4 LYS o 300  TYR o 301  0                                        
SHEET    2 AE1 4 PHE o 308  ILE o 309 -1  O  ILE o 309   N  LYS o 300           
SHEET    3 AE1 4 ARG o 318  TRP o 320 -1  O  TRP o 320   N  PHE o 308           
SHEET    4 AE1 4 LYS o 329  GLN o 330 -1  O  LYS o 329   N  ILE o 319           
SHEET    1 AE2 4 MET o 339  LEU o 342  0                                        
SHEET    2 AE2 4 TYR o 350  GLN o 354 -1  O  CYS o 352   N  PHE o 341           
SHEET    3 AE2 4 ARG o 359  SER o 364 -1  O  TYR o 361   N  ALA o 353           
SHEET    4 AE2 4 PHE o 377  LYS o 378 -1  O  PHE o 377   N  ILE o 360           
SHEET    1 AE3 3 GLY o 386  SER o 388  0                                        
SHEET    2 AE3 3 TYR o 397  GLY o 401 -1  O  CYS o 399   N  ILE o 387           
SHEET    3 AE3 3 LEU o 407  ASP o 411 -1  O  TRP o 410   N  ILE o 398           
SHEET    1 AE4 2 GLN y 144  ASP y 146  0                                        
SHEET    2 AE4 2 LYS y 151  THR y 153 -1  O  THR y 153   N  GLN y 144           
SHEET    1 AE532 VAL e  27  TRP e  30  0                                        
SHEET    2 AE532 ILE e  37  ILE e  43 -1  O  ILE e  39   N  ILE e  29           
SHEET    3 AE532 VAL e  52  ASP e  55 -1  O  ASP e  55   N  LYS e  42           
SHEET    4 AE532 ILE e  80  LEU e  82 -1  O  ILE e  80   N  ILE e  54           
SHEET    5 AE532 VAL f  78  ARG f  82 -1  O  ILE f  81   N  LEU e  81           
SHEET    6 AE532 ARG f  26  LEU f  31 -1  N  LYS f  30   O  LEU f  79           
SHEET    7 AE532 GLY f  40  LEU f  42 -1  O  GLY f  40   N  VAL f  27           
SHEET    8 AE532 LEU f  51  PHE f  59 -1  O  ASN f  54   N  THR f  41           
SHEET    9 AE532 SER f  64  ILE f  73 -1  O  HIS f  65   N  GLU f  58           
SHEET   10 AE532 VAL j 101  LYS j 106 -1  O  VAL j 104   N  PHE f  72           
SHEET   11 AE532 PRO j  43  LEU j  48 -1  N  ILE j  45   O  LEU j 105           
SHEET   12 AE532 LYS j  53  VAL j  58 -1  O  ALA j  56   N  VAL j  44           
SHEET   13 AE532 MET j  67  THR j  77 -1  O  GLU j  70   N  ARG j  57           
SHEET   14 AE532 ASN j  86  LEU j  96 -1  O  LEU j  94   N  LEU j  69           
SHEET   15 AE532 ILE h  92  ILE h  96 -1  N  ILE h  95   O  PHE j  95           
SHEET   16 AE532 GLN h  14  LEU h  19 -1  N  GLU h  18   O  ARG h  93           
SHEET   17 AE532 THR h  24  VAL h  32 -1  O  GLY h  27   N  VAL h  15           
SHEET   18 AE532 ALA h  38  THR h  46 -1  O  LYS h  44   N  TRP h  26           
SHEET   19 AE532 TYR h  84  ILE h  87 -1  O  ILE h  85   N  LEU h  40           
SHEET   20 AE532 ILE b  92  ASP b  99 -1  N  THR b  95   O  ASN h  86           
SHEET   21 AE532 LYS b  19  THR b  24 -1  N  LYS b  19   O  GLU b  98           
SHEET   22 AE532 VAL b  29  ALA b  36 -1  O  GLY b  32   N  LEU b  20           
SHEET   23 AE532 LEU b  43  GLU b  51 -1  O  ASN b  46   N  GLN b  33           
SHEET   24 AE532 ARG b  80  LEU b  87 -1  O  LEU b  87   N  LEU b  43           
SHEET   25 AE532 ILE d  69  VAL d  73 -1  O  ILE d  72   N  ILE b  86           
SHEET   26 AE532 ILE d  18  LEU d  23 -1  N  GLU d  22   O  LYS d  70           
SHEET   27 AE532 THR d  28  GLU d  35 -1  O  GLY d  31   N  VAL d  19           
SHEET   28 AE532 GLN d  43  ALA d  49 -1  O  ARG d  45   N  LYS d  32           
SHEET   29 AE532 GLN d  61  VAL d  64 -1  O  ILE d  62   N  LEU d  44           
SHEET   30 AE532 ILE g  68  ALA g  73 -1  O  LEU g  71   N  PHE d  63           
SHEET   31 AE532 ILE g  15  ILE g  19 -1  N  ASN g  18   O  ILE g  69           
SHEET   32 AE532 ARG g  23  VAL g  25 -1  O  VAL g  25   N  LEU g  17           
SHEET    1 AE619 GLU e  59  PRO e  61  0                                        
SHEET    2 AE619 ILE e  37  ILE e  43 -1  N  ARG e  38   O  ILE e  60           
SHEET    3 AE619 VAL e  52  ASP e  55 -1  O  ASP e  55   N  LYS e  42           
SHEET    4 AE619 ILE e  80  LEU e  82 -1  O  ILE e  80   N  ILE e  54           
SHEET    5 AE619 VAL f  78  ARG f  82 -1  O  ILE f  81   N  LEU e  81           
SHEET    6 AE619 ARG f  26  LEU f  31 -1  N  LYS f  30   O  LEU f  79           
SHEET    7 AE619 GLY f  40  LEU f  42 -1  O  GLY f  40   N  VAL f  27           
SHEET    8 AE619 LEU f  51  PHE f  59 -1  O  ASN f  54   N  THR f  41           
SHEET    9 AE619 SER f  64  ILE f  73 -1  O  HIS f  65   N  GLU f  58           
SHEET   10 AE619 VAL j 101  LYS j 106 -1  O  VAL j 104   N  PHE f  72           
SHEET   11 AE619 PRO j  43  LEU j  48 -1  N  ILE j  45   O  LEU j 105           
SHEET   12 AE619 LYS j  53  VAL j  58 -1  O  ALA j  56   N  VAL j  44           
SHEET   13 AE619 MET j  67  THR j  77 -1  O  GLU j  70   N  ARG j  57           
SHEET   14 AE619 ASN j  86  LEU j  96 -1  O  LEU j  94   N  LEU j  69           
SHEET   15 AE619 ILE h  92  ILE h  96 -1  N  ILE h  95   O  PHE j  95           
SHEET   16 AE619 GLN h  14  LEU h  19 -1  N  GLU h  18   O  ARG h  93           
SHEET   17 AE619 THR h  24  VAL h  32 -1  O  GLY h  27   N  VAL h  15           
SHEET   18 AE619 ALA h  38  THR h  46 -1  O  LYS h  44   N  TRP h  26           
SHEET   19 AE619 ILE h  79  SER h  81 -1  O  ALA h  80   N  LEU h  45           
SHEET    1 AE7 3 LEU g  29  GLY g  31  0                                        
SHEET    2 AE7 3 VAL g  38  ASP g  41 -1  O  VAL g  39   N  ARG g  30           
SHEET    3 AE7 3 GLN g  60  ILE g  63 -1  O  THR g  61   N  LEU g  40           
SHEET    1 AE8 2 MET g  44  GLU g  45  0                                        
SHEET    2 AE8 2 HIS g  55  GLN g  56 -1  O  HIS g  55   N  GLU g  45           
SSBOND   1 CYS L  120    CYS L  122                          1555   1555  2.87  
SSBOND   2 CYS N   16    CYS N   74                          1555   1555  2.51  
LINK         P     G I   1                 O2'   A I  70     1555   1555  1.62  
LINK         OP2   G 6  60                MG    MG 61002     1555   1555  2.17  
LINK         OP1   C 6  61                MG    MG 61003     1555   1555  2.15  
LINK         OP1   G 6  77                MG    MG 61003     1555   1555  2.32  
LINK         OP1   G 6  78                MG    MG 61001     1555   1555  2.10  
LINK         OP1   U 6  80                MG    MG 61002     1555   1555  2.10  
LINK         OP2   U 6  80                MG    MG 61001     1555   1555  2.10  
LINK         OP2   U 6  80                MG    MG 61002     1555   1555  2.76  
LINK         OP1   G 6  81                 K     K 61005     1555   1555  2.41  
LINK         OP2   G 6  81                 K     K 61004     1555   1555  2.14  
LINK         N1    A 5  45                 O4    U 5  74     1555   1555  1.48  
LINK         SG  CYS L 104                ZN    ZN L1000     1555   1555  2.32  
LINK         SG  CYS L 104                ZN    ZN L1001     1555   1555  2.31  
LINK         SG  CYS L 105                ZN    ZN L1000     1555   1555  2.34  
LINK         SG  CYS L 108                ZN    ZN L1000     1555   1555  2.33  
LINK         SG  CYS L 108                ZN    ZN L1002     1555   1555  2.32  
LINK         SG  CYS L 120                ZN    ZN L1002     1555   1555  2.34  
LINK         SG  CYS L 122                ZN    ZN L1001     1555   1555  2.33  
LINK         SG  CYS L 122                ZN    ZN L1002     1555   1555  2.34  
LINK         SG  CYS L 145                ZN    ZN L1002     1555   1555  2.34  
LINK         SG  CYS L 148                ZN    ZN L1000     1555   1555  2.33  
LINK         SG  CYS L 150                ZN    ZN L1001     1555   1555  2.32  
LINK         SG  CYS L 153                ZN    ZN L1001     1555   1555  2.34  
LINK         SG  CYS M  73                ZN    ZN M1000     1555   1555  2.31  
LINK         SG  CYS M  81                ZN    ZN M1000     1555   1555  2.33  
LINK         SG  CYS M  87                ZN    ZN M1000     1555   1555  2.32  
LINK         NE2 HIS M  91                ZN    ZN M1000     1555   1555  2.07  
LINK         SG  CYS N  13                ZN    ZN N 402     1555   1555  2.35  
LINK         SG  CYS N  16                ZN    ZN N 402     1555   1555  2.33  
LINK         SG  CYS N  34                ZN    ZN N 401     1555   1555  2.32  
LINK         SG  CYS N  37                ZN    ZN N 401     1555   1555  2.33  
LINK         SG  CYS N  61                ZN    ZN N 401     1555   1555  2.33  
LINK         SG  CYS N  64                ZN    ZN N 401     1555   1555  2.33  
LINK         SG  CYS N  71                ZN    ZN N 402     1555   1555  2.31  
LINK         SG  CYS N  74                ZN    ZN N 402     1555   1555  2.34  
CISPEP   1 PHE A  239    PRO A  240          0        -5.33                     
CISPEP   2 ILE A 1488    PRO A 1489          0        -7.28                     
CISPEP   3 LYS o  366    PRO o  367          0        -0.48                     
CISPEP   4 ALA d   81    PRO d   82          0       -11.84                     
SITE     1 AC1  3   G 6  78    A 6  79    U 6  80                               
SITE     1 AC2  3   A 6  59    G 6  60    U 6  80                               
SITE     1 AC3  3   G 6  60    C 6  61    G 6  77                               
SITE     1 AC4  2   A 6  62    G 6  81                                          
SITE     1 AC5  1   G 6  81                                                     
SITE     1 AC6 11 ARG A 236  LYS A 517  HIS A 659  LYS A 684                    
SITE     2 AC6 11 HIS A 685  TYR A 688  TYR A 689  LYS A 697                    
SITE     3 AC6 11 GLY A 698  ASN A1618  ARG c 170                               
SITE     1 AC7 17 ASN A 405  LEU C 142  HIS C 143  GLY C 145                    
SITE     2 AC7 17 LYS C 146  THR C 147  SER C 148  ARG C 176                    
SITE     3 AC7 17 LEU C 189  SER C 190  ALA C 215  GLY C 217                    
SITE     4 AC7 17 LYS C 269  ARG C 272  SER C 315  THR C 316                    
SITE     5 AC7 17 LYS C 317                                                     
SITE     1 AC8  4 CYS L 104  CYS L 105  CYS L 108  CYS L 148                    
SITE     1 AC9  6 CYS L 104  CYS L 108  CYS L 122  CYS L 150                    
SITE     2 AC9  6 CYS L 153   ZN L1002                                          
SITE     1 AD1  6 CYS L 108  CYS L 120  CYS L 122  CYS L 145                    
SITE     2 AD1  6 CYS L 150   ZN L1001                                          
SITE     1 AD2  4 CYS M  73  CYS M  81  CYS M  87  HIS M  91                    
SITE     1 AD3  4 CYS N  34  CYS N  37  CYS N  61  CYS N  64                    
SITE     1 AD4  4 CYS N  13  CYS N  16  CYS N  71  CYS N  74                    
CRYST1    1.000    1.000    1.000  90.00  90.00  90.00 P 1           1          
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      0.001697  0.000000  0.000000        0.00000                         
SCALE2      0.000000  0.001697  0.000000        0.00000                         
SCALE3      0.000000  0.000000  0.001697        0.00000                         
(ATOM LINES ARE NOT SHOWN.)
END                                                                             
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