HEADER MEMBRANE PROTEIN 03-APR-17 5NL2
TITLE CRYO-EM STRUCTURE OF THE MTMEM16A ION CHANNEL AT 6.6 A RESOLUTION.
COMPND MOL_ID: 1;
COMPND 2 MOLECULE: ANOCTAMIN-1;
COMPND 3 CHAIN: A, B;
COMPND 4 SYNONYM: TRANSMEMBRANE PROTEIN 16A;
COMPND 5 ENGINEERED: YES
SOURCE MOL_ID: 1;
SOURCE 2 ORGANISM_SCIENTIFIC: MUS MUSCULUS;
SOURCE 3 ORGANISM_COMMON: MOUSE;
SOURCE 4 ORGANISM_TAXID: 10090;
SOURCE 5 GENE: ANO1, TMEM16A;
SOURCE 6 EXPRESSION_SYSTEM: HOMO SAPIENS;
SOURCE 7 EXPRESSION_SYSTEM_COMMON: HUMAN;
SOURCE 8 EXPRESSION_SYSTEM_TAXID: 9606;
SOURCE 9 EXPRESSION_SYSTEM_CELL_LINE: HEK293 STABLE MTMEM16A CELL LINE (FLP-
SOURCE 10 IN SYSTEM);
SOURCE 11 EXPRESSION_SYSTEM_ATCC_NUMBER: CRL-1573
KEYWDS TMEM16 FAMILY, ION CHANNEL, MEMBRANE PROTEIN, CRYO-EM
EXPDTA ELECTRON MICROSCOPY
AUTHOR C.PAULINO,Y.NELDNER,K.M.LAM,V.KALIENKOVA,J.D.BRUNNER,S.SCHENCK,
AUTHOR 2 R.DUTZLER
REVDAT 3 28-FEB-18 5NL2 1 SOURCE
REVDAT 2 30-AUG-17 5NL2 1 REMARK
REVDAT 1 07-JUN-17 5NL2 0
JRNL AUTH C.PAULINO,Y.NELDNER,A.K.LAM,V.KALIENKOVA,J.D.BRUNNER,
JRNL AUTH 2 S.SCHENCK,R.DUTZLER
JRNL TITL STRUCTURAL BASIS FOR ANION CONDUCTION IN THE
JRNL TITL 2 CALCIUM-ACTIVATED CHLORIDE CHANNEL TMEM16A.
JRNL REF ELIFE V. 6 2017
JRNL REFN ESSN 2050-084X
JRNL PMID 28561733
JRNL DOI 10.7554/ELIFE.26232
REMARK 2
REMARK 2 RESOLUTION. 6.60 ANGSTROMS.
REMARK 3
REMARK 3 REFINEMENT.
REMARK 3 SOFTWARE PACKAGES : RELION, SERIALEM, CTFFIND, COOT,
REMARK 3 PHENIX, RELION, RELION, RELION, RELION
REMARK 3 RECONSTRUCTION SCHEMA : NULL
REMARK 3
REMARK 3 EM MAP-MODEL FITTING AND REFINEMENT
REMARK 3 PDB ENTRY : 4WIT
REMARK 3 REFINEMENT SPACE : NULL
REMARK 3 REFINEMENT PROTOCOL : RIGID BODY FIT
REMARK 3 REFINEMENT TARGET : NULL
REMARK 3 OVERALL ANISOTROPIC B VALUE : NULL
REMARK 3
REMARK 3 FITTING PROCEDURE : NULL
REMARK 3
REMARK 3 EM IMAGE RECONSTRUCTION STATISTICS
REMARK 3 NOMINAL PIXEL SIZE (ANGSTROMS) : NULL
REMARK 3 ACTUAL PIXEL SIZE (ANGSTROMS) : NULL
REMARK 3 EFFECTIVE RESOLUTION (ANGSTROMS) : 6.600
REMARK 3 NUMBER OF PARTICLES : 213243
REMARK 3 CTF CORRECTION METHOD : PHASE FLIPPING AND AMPLITUDE
REMARK 3 CORRECTION
REMARK 3
REMARK 3 EM RECONSTRUCTION MAGNIFICATION CALIBRATION: NULL
REMARK 3
REMARK 3 OTHER DETAILS: NULL
REMARK 4
REMARK 4 5NL2 COMPLIES WITH FORMAT V. 3.30, 13-JUL-11
REMARK 100
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBE ON 03-APR-17.
REMARK 100 THE DEPOSITION ID IS D_1200004266.
REMARK 245
REMARK 245 EXPERIMENTAL DETAILS
REMARK 245 RECONSTRUCTION METHOD : SINGLE PARTICLE
REMARK 245 SPECIMEN TYPE : NULL
REMARK 245
REMARK 245 ELECTRON MICROSCOPE SAMPLE
REMARK 245 SAMPLE TYPE : PARTICLE
REMARK 245 PARTICLE TYPE : POINT
REMARK 245 NAME OF SAMPLE : MTMEM16A
REMARK 245 SAMPLE CONCENTRATION (MG ML-1) : 3.08
REMARK 245 SAMPLE SUPPORT DETAILS : NULL
REMARK 245 SAMPLE VITRIFICATION DETAILS : 2.5 UL SAMPLE VOLUME 1-5 SEC
REMARK 245 BLOTTING TIME
REMARK 245 SAMPLE BUFFER : NULL
REMARK 245 PH : 7.50
REMARK 245 SAMPLE DETAILS : NULL
REMARK 245
REMARK 245 DATA ACQUISITION
REMARK 245 DATE OF EXPERIMENT : NULL
REMARK 245 NUMBER OF MICROGRAPHS-IMAGES : 5503
REMARK 245 TEMPERATURE (KELVIN) : NULL
REMARK 245 MICROSCOPE MODEL : FEI TITAN KRIOS
REMARK 245 DETECTOR TYPE : GATAN K2 SUMMIT (4K X 4K)
REMARK 245 MINIMUM DEFOCUS (NM) : 500.00
REMARK 245 MAXIMUM DEFOCUS (NM) : 3800.00
REMARK 245 MINIMUM TILT ANGLE (DEGREES) : NULL
REMARK 245 MAXIMUM TILT ANGLE (DEGREES) : NULL
REMARK 245 NOMINAL CS : 2.70
REMARK 245 IMAGING MODE : BRIGHT FIELD
REMARK 245 ELECTRON DOSE (ELECTRONS NM**-2) : 80.00
REMARK 245 ILLUMINATION MODE : FLOOD BEAM
REMARK 245 NOMINAL MAGNIFICATION : 37037
REMARK 245 CALIBRATED MAGNIFICATION : 37037
REMARK 245 SOURCE : FIELD EMISSION GUN
REMARK 245 ACCELERATION VOLTAGE (KV) : 300
REMARK 245 IMAGING DETAILS : NULL
REMARK 247
REMARK 247 ELECTRON MICROSCOPY
REMARK 247 THE COORDINATES IN THIS ENTRY WERE GENERATED FROM ELECTRON
REMARK 247 MICROSCOPY DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE
REMARK 247 THAT CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES
REMARK 247 ON THESE RECORDS ARE MEANINGLESS EXCEPT FOR THE CALCULATION
REMARK 247 OF THE STRUCTURE FACTORS.
REMARK 300
REMARK 300 BIOMOLECULE: 1
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON
REMARK 300 BURIED SURFACE AREA.
REMARK 350
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS
REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.
REMARK 350
REMARK 350 BIOMOLECULE: 1
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: DIMERIC
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B
REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000
REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000
REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000
REMARK 465
REMARK 465 MISSING RESIDUES
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)
REMARK 465
REMARK 465 M RES C SSSEQI
REMARK 465 MET A 1
REMARK 465 ARG A 2
REMARK 465 VAL A 3
REMARK 465 PRO A 4
REMARK 465 GLU A 5
REMARK 465 LYS A 6
REMARK 465 TYR A 7
REMARK 465 SER A 8
REMARK 465 THR A 9
REMARK 465 LEU A 10
REMARK 465 PRO A 11
REMARK 465 ALA A 12
REMARK 465 GLU A 13
REMARK 465 ASP A 14
REMARK 465 ARG A 15
REMARK 465 SER A 16
REMARK 465 VAL A 17
REMARK 465 HIS A 18
REMARK 465 ILE A 19
REMARK 465 VAL A 20
REMARK 465 ASN A 21
REMARK 465 ILE A 22
REMARK 465 CYS A 23
REMARK 465 ALA A 24
REMARK 465 ILE A 25
REMARK 465 GLU A 26
REMARK 465 ASP A 27
REMARK 465 LEU A 28
REMARK 465 GLY A 29
REMARK 465 TYR A 30
REMARK 465 LEU A 31
REMARK 465 PRO A 32
REMARK 465 SER A 33
REMARK 465 GLU A 34
REMARK 465 GLY A 35
REMARK 465 THR A 36
REMARK 465 LEU A 37
REMARK 465 LEU A 38
REMARK 465 ASN A 39
REMARK 465 SER A 40
REMARK 465 LEU A 41
REMARK 465 SER A 42
REMARK 465 VAL A 43
REMARK 465 ASP A 44
REMARK 465 PRO A 45
REMARK 465 ASP A 46
REMARK 465 ALA A 47
REMARK 465 GLU A 48
REMARK 465 CYS A 49
REMARK 465 LYS A 50
REMARK 465 TYR A 51
REMARK 465 GLY A 52
REMARK 465 LEU A 53
REMARK 465 TYR A 54
REMARK 465 PHE A 55
REMARK 465 ARG A 56
REMARK 465 ASP A 57
REMARK 465 GLY A 58
REMARK 465 LYS A 59
REMARK 465 ARG A 60
REMARK 465 LYS A 61
REMARK 465 VAL A 62
REMARK 465 ASP A 63
REMARK 465 TYR A 64
REMARK 465 ILE A 65
REMARK 465 LEU A 66
REMARK 465 VAL A 67
REMARK 465 TYR A 68
REMARK 465 HIS A 69
REMARK 465 HIS A 70
REMARK 465 LYS A 71
REMARK 465 ARG A 72
REMARK 465 ALA A 73
REMARK 465 SER A 74
REMARK 465 GLY A 75
REMARK 465 SER A 76
REMARK 465 ARG A 77
REMARK 465 THR A 78
REMARK 465 LEU A 79
REMARK 465 ALA A 80
REMARK 465 ARG A 81
REMARK 465 ARG A 82
REMARK 465 GLY A 83
REMARK 465 LEU A 84
REMARK 465 GLN A 85
REMARK 465 ASN A 86
REMARK 465 ASP A 87
REMARK 465 MET A 88
REMARK 465 VAL A 89
REMARK 465 LEU A 90
REMARK 465 GLY A 91
REMARK 465 THR A 92
REMARK 465 ARG A 93
REMARK 465 SER A 94
REMARK 465 VAL A 95
REMARK 465 ARG A 96
REMARK 465 GLN A 97
REMARK 465 ASP A 98
REMARK 465 GLN A 99
REMARK 465 PRO A 100
REMARK 465 LEU A 101
REMARK 465 PRO A 102
REMARK 465 GLY A 103
REMARK 465 LYS A 104
REMARK 465 GLY A 105
REMARK 465 SER A 106
REMARK 465 PRO A 107
REMARK 465 VAL A 108
REMARK 465 ASP A 109
REMARK 465 ALA A 110
REMARK 465 GLY A 111
REMARK 465 SER A 112
REMARK 465 PRO A 113
REMARK 465 GLU A 114
REMARK 465 VAL A 115
REMARK 465 PRO A 116
REMARK 465 MET A 117
REMARK 465 ASP A 118
REMARK 465 TYR A 119
REMARK 465 HIS A 120
REMARK 465 GLU A 121
REMARK 465 ASP A 122
REMARK 465 ARG A 128
REMARK 465 GLU A 129
REMARK 465 GLU A 130
REMARK 465 TYR A 131
REMARK 465 GLU A 132
REMARK 465 GLY A 133
REMARK 465 ASN A 134
REMARK 465 LEU A 135
REMARK 465 LEU A 136
REMARK 465 GLU A 137
REMARK 465 ALA A 138
REMARK 465 GLY A 139
REMARK 465 LEU A 140
REMARK 465 GLU A 141
REMARK 465 LEU A 142
REMARK 465 GLU A 143
REMARK 465 ASN A 144
REMARK 465 ASP A 145
REMARK 465 GLU A 146
REMARK 465 ASP A 147
REMARK 465 THR A 148
REMARK 465 LYS A 149
REMARK 465 ILE A 150
REMARK 465 HIS A 151
REMARK 465 GLY A 152
REMARK 465 VAL A 153
REMARK 465 GLY A 154
REMARK 465 PHE A 155
REMARK 465 VAL A 156
REMARK 465 LYS A 157
REMARK 465 ILE A 158
REMARK 465 HIS A 159
REMARK 465 ALA A 160
REMARK 465 PRO A 161
REMARK 465 TRP A 162
REMARK 465 HIS A 163
REMARK 465 VAL A 164
REMARK 465 LEU A 165
REMARK 465 CYS A 166
REMARK 465 THR A 202
REMARK 465 ASP A 203
REMARK 465 GLN A 215
REMARK 465 THR A 216
REMARK 465 THR A 217
REMARK 465 LYS A 218
REMARK 465 ARG A 219
REMARK 465 LEU A 220
REMARK 465 SER A 221
REMARK 465 TYR A 222
REMARK 465 PRO A 223
REMARK 465 PHE A 224
REMARK 465 SER A 225
REMARK 465 ARG A 226
REMARK 465 GLU A 227
REMARK 465 LYS A 228
REMARK 465 GLN A 229
REMARK 465 HIS A 230
REMARK 465 LEU A 231
REMARK 465 PHE A 232
REMARK 465 ASP A 233
REMARK 465 LEU A 234
REMARK 465 THR A 235
REMARK 465 ASP A 236
REMARK 465 ARG A 237
REMARK 465 ASP A 238
REMARK 465 SER A 239
REMARK 465 PHE A 240
REMARK 465 PHE A 241
REMARK 465 LYS A 255
REMARK 465 ARG A 256
REMARK 465 THR A 257
REMARK 465 THR A 258
REMARK 465 CYS A 259
REMARK 465 THR A 260
REMARK 465 LYS A 261
REMARK 465 ALA A 262
REMARK 465 LYS A 263
REMARK 465 TYR A 264
REMARK 465 SER A 265
REMARK 465 MET A 266
REMARK 465 GLY A 267
REMARK 465 ILE A 268
REMARK 465 THR A 269
REMARK 465 SER A 270
REMARK 465 LEU A 271
REMARK 465 LEU A 272
REMARK 465 ALA A 273
REMARK 465 ASN A 274
REMARK 465 GLY A 275
REMARK 465 VAL A 276
REMARK 465 TYR A 277
REMARK 465 LEU A 283
REMARK 465 HIS A 284
REMARK 465 ASP A 285
REMARK 465 GLY A 286
REMARK 465 ASP A 287
REMARK 465 TYR A 288
REMARK 465 GLU A 289
REMARK 465 GLY A 290
REMARK 465 ASP A 291
REMARK 465 ASN A 292
REMARK 465 VAL A 293
REMARK 465 GLU A 294
REMARK 465 ALA A 306
REMARK 465 SER A 307
REMARK 465 TYR A 308
REMARK 465 GLY A 309
REMARK 465 VAL A 310
REMARK 465 PHE A 311
REMARK 465 TYR A 312
REMARK 465 LYS A 313
REMARK 465 TYR A 314
REMARK 465 GLY A 356
REMARK 465 CYS A 357
REMARK 465 ALA A 358
REMARK 465 THR A 359
REMARK 465 VAL A 360
REMARK 465 ASP A 361
REMARK 465 GLU A 362
REMARK 465 ASN A 363
REMARK 465 ILE A 364
REMARK 465 PRO A 365
REMARK 465 SER A 366
REMARK 465 MET A 367
REMARK 465 GLU A 368
REMARK 465 MET A 369
REMARK 465 CYS A 370
REMARK 465 ASP A 371
REMARK 465 GLN A 372
REMARK 465 ARG A 373
REMARK 465 TYR A 374
REMARK 465 ASN A 375
REMARK 465 ILE A 376
REMARK 465 THR A 377
REMARK 465 MET A 378
REMARK 465 CYS A 379
REMARK 465 PRO A 380
REMARK 465 LEU A 381
REMARK 465 CYS A 382
REMARK 465 ASP A 383
REMARK 465 LYS A 384
REMARK 465 THR A 385
REMARK 465 CYS A 386
REMARK 465 SER A 387
REMARK 465 TYR A 388
REMARK 465 TRP A 389
REMARK 465 LYS A 390
REMARK 465 MET A 391
REMARK 465 SER A 392
REMARK 465 SER A 393
REMARK 465 ALA A 394
REMARK 465 CYS A 395
REMARK 465 ALA A 396
REMARK 465 THR A 397
REMARK 465 ALA A 398
REMARK 465 ARG A 399
REMARK 465 ALA A 400
REMARK 465 SER A 401
REMARK 465 HIS A 402
REMARK 465 LEU A 403
REMARK 465 PHE A 404
REMARK 465 ASP A 405
REMARK 465 ASN A 406
REMARK 465 PRO A 407
REMARK 465 ALA A 408
REMARK 465 ASP A 439
REMARK 465 LEU A 440
REMARK 465 THR A 441
REMARK 465 GLY A 442
REMARK 465 PHE A 443
REMARK 465 GLU A 444
REMARK 465 GLU A 445
REMARK 465 GLU A 446
REMARK 465 GLU A 447
REMARK 465 GLU A 448
REMARK 465 ALA A 449
REMARK 465 VAL A 450
REMARK 465 LYS A 451
REMARK 465 ASP A 452
REMARK 465 HIS A 453
REMARK 465 PRO A 454
REMARK 465 ARG A 455
REMARK 465 ALA A 456
REMARK 465 GLU A 457
REMARK 465 TYR A 458
REMARK 465 GLU A 459
REMARK 465 ALA A 460
REMARK 465 ARG A 461
REMARK 465 VAL A 462
REMARK 465 LEU A 463
REMARK 465 GLU A 464
REMARK 465 LYS A 465
REMARK 465 SER A 466
REMARK 465 LEU A 467
REMARK 465 ARG A 468
REMARK 465 LYS A 469
REMARK 465 GLU A 470
REMARK 465 SER A 471
REMARK 465 ARG A 472
REMARK 465 ASN A 473
REMARK 465 LYS A 474
REMARK 465 GLU A 475
REMARK 465 THR A 476
REMARK 465 ASP A 477
REMARK 465 LYS A 478
REMARK 465 VAL A 479
REMARK 465 LYS A 480
REMARK 465 LEU A 481
REMARK 465 THR A 482
REMARK 465 TRP A 483
REMARK 465 ARG A 484
REMARK 465 ASP A 485
REMARK 465 ALA A 521
REMARK 465 LEU A 522
REMARK 465 ALA A 523
REMARK 465 MET A 524
REMARK 465 ASN A 525
REMARK 465 SER A 526
REMARK 465 SER A 527
REMARK 465 PRO A 528
REMARK 465 SER A 529
REMARK 465 VAL A 530
REMARK 465 ARG A 531
REMARK 465 SER A 532
REMARK 465 ASN A 533
REMARK 465 ILE A 534
REMARK 465 LYS A 603
REMARK 465 GLY A 604
REMARK 465 ARG A 605
REMARK 465 PHE A 606
REMARK 465 VAL A 607
REMARK 465 GLY A 608
REMARK 465 ARG A 609
REMARK 465 PRO A 610
REMARK 465 GLY A 611
REMARK 465 ASP A 612
REMARK 465 TYR A 613
REMARK 465 VAL A 614
REMARK 465 TYR A 615
REMARK 465 ILE A 616
REMARK 465 PHE A 617
REMARK 465 ARG A 618
REMARK 465 SER A 619
REMARK 465 PHE A 620
REMARK 465 ARG A 621
REMARK 465 MET A 622
REMARK 465 GLU A 623
REMARK 465 GLU A 624
REMARK 465 CYS A 625
REMARK 465 ALA A 626
REMARK 465 PRO A 627
REMARK 465 GLY A 628
REMARK 465 GLY A 629
REMARK 465 CYS A 630
REMARK 465 LEU A 631
REMARK 465 MET A 632
REMARK 465 LEU A 667
REMARK 465 LYS A 668
REMARK 465 LEU A 669
REMARK 465 ARG A 670
REMARK 465 ARG A 671
REMARK 465 GLN A 672
REMARK 465 SER A 673
REMARK 465 PRO A 674
REMARK 465 SER A 675
REMARK 465 ASP A 676
REMARK 465 ARG A 677
REMARK 465 GLU A 678
REMARK 465 GLU A 679
REMARK 465 TYR A 680
REMARK 465 LEU A 693
REMARK 465 GLU A 694
REMARK 465 PRO A 695
REMARK 465 PHE A 696
REMARK 465 THR A 782
REMARK 465 SER A 783
REMARK 465 ASP A 784
REMARK 465 PHE A 785
REMARK 465 ILE A 786
REMARK 465 PRO A 787
REMARK 465 ARG A 788
REMARK 465 LEU A 789
REMARK 465 VAL A 790
REMARK 465 TYR A 791
REMARK 465 LEU A 792
REMARK 465 TYR A 793
REMARK 465 MET A 794
REMARK 465 TYR A 795
REMARK 465 SER A 796
REMARK 465 GLN A 797
REMARK 465 ASN A 798
REMARK 465 GLY A 799
REMARK 465 THR A 800
REMARK 465 MET A 801
REMARK 465 HIS A 802
REMARK 465 GLY A 803
REMARK 465 PHE A 804
REMARK 465 VAL A 805
REMARK 465 ASN A 806
REMARK 465 HIS A 807
REMARK 465 THR A 808
REMARK 465 LEU A 809
REMARK 465 SER A 810
REMARK 465 SER A 811
REMARK 465 PHE A 812
REMARK 465 ASN A 813
REMARK 465 VAL A 814
REMARK 465 SER A 815
REMARK 465 ASP A 816
REMARK 465 PHE A 817
REMARK 465 GLN A 818
REMARK 465 ASN A 819
REMARK 465 GLY A 820
REMARK 465 THR A 821
REMARK 465 ALA A 822
REMARK 465 PRO A 823
REMARK 465 ASN A 824
REMARK 465 ASP A 825
REMARK 465 PRO A 826
REMARK 465 LEU A 827
REMARK 465 ASP A 828
REMARK 465 LEU A 829
REMARK 465 GLY A 830
REMARK 465 TYR A 831
REMARK 465 GLU A 832
REMARK 465 VAL A 833
REMARK 465 GLN A 834
REMARK 465 ILE A 835
REMARK 465 CYS A 836
REMARK 465 ARG A 837
REMARK 465 TYR A 838
REMARK 465 LYS A 839
REMARK 465 ASP A 840
REMARK 465 TYR A 841
REMARK 465 ARG A 842
REMARK 465 GLU A 843
REMARK 465 PRO A 844
REMARK 465 PRO A 845
REMARK 465 TRP A 846
REMARK 465 SER A 847
REMARK 465 GLU A 848
REMARK 465 HIS A 849
REMARK 465 LYS A 850
REMARK 465 TYR A 851
REMARK 465 ASP A 852
REMARK 465 ILE A 853
REMARK 465 SER A 854
REMARK 465 ILE A 886
REMARK 465 PRO A 887
REMARK 465 ASP A 888
REMARK 465 ILE A 889
REMARK 465 PRO A 890
REMARK 465 LYS A 891
REMARK 465 ARG A 910
REMARK 465 GLU A 911
REMARK 465 GLU A 912
REMARK 465 GLN A 913
REMARK 465 GLY A 914
REMARK 465 LYS A 915
REMARK 465 GLN A 916
REMARK 465 GLN A 917
REMARK 465 LEU A 918
REMARK 465 LEU A 919
REMARK 465 ASP A 920
REMARK 465 THR A 921
REMARK 465 TRP A 922
REMARK 465 MET A 923
REMARK 465 GLU A 924
REMARK 465 LYS A 925
REMARK 465 GLU A 926
REMARK 465 LYS A 927
REMARK 465 PRO A 928
REMARK 465 ARG A 929
REMARK 465 ASP A 930
REMARK 465 VAL A 931
REMARK 465 PRO A 932
REMARK 465 CYS A 933
REMARK 465 ASN A 934
REMARK 465 ASN A 935
REMARK 465 HIS A 936
REMARK 465 SER A 937
REMARK 465 PRO A 938
REMARK 465 THR A 939
REMARK 465 THR A 940
REMARK 465 HIS A 941
REMARK 465 PRO A 942
REMARK 465 GLU A 943
REMARK 465 ALA A 944
REMARK 465 GLY A 945
REMARK 465 ASP A 946
REMARK 465 GLY A 947
REMARK 465 SER A 948
REMARK 465 PRO A 949
REMARK 465 VAL A 950
REMARK 465 PRO A 951
REMARK 465 SER A 952
REMARK 465 TYR A 953
REMARK 465 GLU A 954
REMARK 465 TYR A 955
REMARK 465 HIS A 956
REMARK 465 GLY A 957
REMARK 465 ASP A 958
REMARK 465 ALA A 959
REMARK 465 LEU A 960
REMARK 465 MET B 1
REMARK 465 ARG B 2
REMARK 465 VAL B 3
REMARK 465 PRO B 4
REMARK 465 GLU B 5
REMARK 465 LYS B 6
REMARK 465 TYR B 7
REMARK 465 SER B 8
REMARK 465 THR B 9
REMARK 465 LEU B 10
REMARK 465 PRO B 11
REMARK 465 ALA B 12
REMARK 465 GLU B 13
REMARK 465 ASP B 14
REMARK 465 ARG B 15
REMARK 465 SER B 16
REMARK 465 VAL B 17
REMARK 465 HIS B 18
REMARK 465 ILE B 19
REMARK 465 VAL B 20
REMARK 465 ASN B 21
REMARK 465 ILE B 22
REMARK 465 CYS B 23
REMARK 465 ALA B 24
REMARK 465 ILE B 25
REMARK 465 GLU B 26
REMARK 465 ASP B 27
REMARK 465 LEU B 28
REMARK 465 GLY B 29
REMARK 465 TYR B 30
REMARK 465 LEU B 31
REMARK 465 PRO B 32
REMARK 465 SER B 33
REMARK 465 GLU B 34
REMARK 465 GLY B 35
REMARK 465 THR B 36
REMARK 465 LEU B 37
REMARK 465 LEU B 38
REMARK 465 ASN B 39
REMARK 465 SER B 40
REMARK 465 LEU B 41
REMARK 465 SER B 42
REMARK 465 VAL B 43
REMARK 465 ASP B 44
REMARK 465 PRO B 45
REMARK 465 ASP B 46
REMARK 465 ALA B 47
REMARK 465 GLU B 48
REMARK 465 CYS B 49
REMARK 465 LYS B 50
REMARK 465 TYR B 51
REMARK 465 GLY B 52
REMARK 465 LEU B 53
REMARK 465 TYR B 54
REMARK 465 PHE B 55
REMARK 465 ARG B 56
REMARK 465 ASP B 57
REMARK 465 GLY B 58
REMARK 465 LYS B 59
REMARK 465 ARG B 60
REMARK 465 LYS B 61
REMARK 465 VAL B 62
REMARK 465 ASP B 63
REMARK 465 TYR B 64
REMARK 465 ILE B 65
REMARK 465 LEU B 66
REMARK 465 VAL B 67
REMARK 465 TYR B 68
REMARK 465 HIS B 69
REMARK 465 HIS B 70
REMARK 465 LYS B 71
REMARK 465 ARG B 72
REMARK 465 ALA B 73
REMARK 465 SER B 74
REMARK 465 GLY B 75
REMARK 465 SER B 76
REMARK 465 ARG B 77
REMARK 465 THR B 78
REMARK 465 LEU B 79
REMARK 465 ALA B 80
REMARK 465 ARG B 81
REMARK 465 ARG B 82
REMARK 465 GLY B 83
REMARK 465 LEU B 84
REMARK 465 GLN B 85
REMARK 465 ASN B 86
REMARK 465 ASP B 87
REMARK 465 MET B 88
REMARK 465 VAL B 89
REMARK 465 LEU B 90
REMARK 465 GLY B 91
REMARK 465 THR B 92
REMARK 465 ARG B 93
REMARK 465 SER B 94
REMARK 465 VAL B 95
REMARK 465 ARG B 96
REMARK 465 GLN B 97
REMARK 465 ASP B 98
REMARK 465 GLN B 99
REMARK 465 PRO B 100
REMARK 465 LEU B 101
REMARK 465 PRO B 102
REMARK 465 GLY B 103
REMARK 465 LYS B 104
REMARK 465 GLY B 105
REMARK 465 SER B 106
REMARK 465 PRO B 107
REMARK 465 VAL B 108
REMARK 465 ASP B 109
REMARK 465 ALA B 110
REMARK 465 GLY B 111
REMARK 465 SER B 112
REMARK 465 PRO B 113
REMARK 465 GLU B 114
REMARK 465 VAL B 115
REMARK 465 PRO B 116
REMARK 465 MET B 117
REMARK 465 ASP B 118
REMARK 465 TYR B 119
REMARK 465 HIS B 120
REMARK 465 GLU B 121
REMARK 465 ASP B 122
REMARK 465 ARG B 128
REMARK 465 GLU B 129
REMARK 465 GLU B 130
REMARK 465 TYR B 131
REMARK 465 GLU B 132
REMARK 465 GLY B 133
REMARK 465 ASN B 134
REMARK 465 LEU B 135
REMARK 465 LEU B 136
REMARK 465 GLU B 137
REMARK 465 ALA B 138
REMARK 465 GLY B 139
REMARK 465 LEU B 140
REMARK 465 GLU B 141
REMARK 465 LEU B 142
REMARK 465 GLU B 143
REMARK 465 ASN B 144
REMARK 465 ASP B 145
REMARK 465 GLU B 146
REMARK 465 ASP B 147
REMARK 465 THR B 148
REMARK 465 LYS B 149
REMARK 465 ILE B 150
REMARK 465 HIS B 151
REMARK 465 GLY B 152
REMARK 465 VAL B 153
REMARK 465 GLY B 154
REMARK 465 PHE B 155
REMARK 465 VAL B 156
REMARK 465 LYS B 157
REMARK 465 ILE B 158
REMARK 465 HIS B 159
REMARK 465 ALA B 160
REMARK 465 PRO B 161
REMARK 465 TRP B 162
REMARK 465 HIS B 163
REMARK 465 VAL B 164
REMARK 465 LEU B 165
REMARK 465 CYS B 166
REMARK 465 THR B 202
REMARK 465 ASP B 203
REMARK 465 GLN B 215
REMARK 465 THR B 216
REMARK 465 THR B 217
REMARK 465 LYS B 218
REMARK 465 ARG B 219
REMARK 465 LEU B 220
REMARK 465 SER B 221
REMARK 465 TYR B 222
REMARK 465 PRO B 223
REMARK 465 PHE B 224
REMARK 465 SER B 225
REMARK 465 ARG B 226
REMARK 465 GLU B 227
REMARK 465 LYS B 228
REMARK 465 GLN B 229
REMARK 465 HIS B 230
REMARK 465 LEU B 231
REMARK 465 PHE B 232
REMARK 465 ASP B 233
REMARK 465 LEU B 234
REMARK 465 THR B 235
REMARK 465 ASP B 236
REMARK 465 ARG B 237
REMARK 465 ASP B 238
REMARK 465 SER B 239
REMARK 465 PHE B 240
REMARK 465 PHE B 241
REMARK 465 LYS B 255
REMARK 465 ARG B 256
REMARK 465 THR B 257
REMARK 465 THR B 258
REMARK 465 CYS B 259
REMARK 465 THR B 260
REMARK 465 LYS B 261
REMARK 465 ALA B 262
REMARK 465 LYS B 263
REMARK 465 TYR B 264
REMARK 465 SER B 265
REMARK 465 MET B 266
REMARK 465 GLY B 267
REMARK 465 ILE B 268
REMARK 465 THR B 269
REMARK 465 SER B 270
REMARK 465 LEU B 271
REMARK 465 LEU B 272
REMARK 465 ALA B 273
REMARK 465 ASN B 274
REMARK 465 GLY B 275
REMARK 465 VAL B 276
REMARK 465 TYR B 277
REMARK 465 LEU B 283
REMARK 465 HIS B 284
REMARK 465 ASP B 285
REMARK 465 GLY B 286
REMARK 465 ASP B 287
REMARK 465 TYR B 288
REMARK 465 GLU B 289
REMARK 465 GLY B 290
REMARK 465 ASP B 291
REMARK 465 ASN B 292
REMARK 465 VAL B 293
REMARK 465 GLU B 294
REMARK 465 ALA B 306
REMARK 465 SER B 307
REMARK 465 TYR B 308
REMARK 465 GLY B 309
REMARK 465 VAL B 310
REMARK 465 PHE B 311
REMARK 465 TYR B 312
REMARK 465 LYS B 313
REMARK 465 TYR B 314
REMARK 465 GLY B 356
REMARK 465 CYS B 357
REMARK 465 ALA B 358
REMARK 465 THR B 359
REMARK 465 VAL B 360
REMARK 465 ASP B 361
REMARK 465 GLU B 362
REMARK 465 ASN B 363
REMARK 465 ILE B 364
REMARK 465 PRO B 365
REMARK 465 SER B 366
REMARK 465 MET B 367
REMARK 465 GLU B 368
REMARK 465 MET B 369
REMARK 465 CYS B 370
REMARK 465 ASP B 371
REMARK 465 GLN B 372
REMARK 465 ARG B 373
REMARK 465 TYR B 374
REMARK 465 ASN B 375
REMARK 465 ILE B 376
REMARK 465 THR B 377
REMARK 465 MET B 378
REMARK 465 CYS B 379
REMARK 465 PRO B 380
REMARK 465 LEU B 381
REMARK 465 CYS B 382
REMARK 465 ASP B 383
REMARK 465 LYS B 384
REMARK 465 THR B 385
REMARK 465 CYS B 386
REMARK 465 SER B 387
REMARK 465 TYR B 388
REMARK 465 TRP B 389
REMARK 465 LYS B 390
REMARK 465 MET B 391
REMARK 465 SER B 392
REMARK 465 SER B 393
REMARK 465 ALA B 394
REMARK 465 CYS B 395
REMARK 465 ALA B 396
REMARK 465 THR B 397
REMARK 465 ALA B 398
REMARK 465 ARG B 399
REMARK 465 ALA B 400
REMARK 465 SER B 401
REMARK 465 HIS B 402
REMARK 465 LEU B 403
REMARK 465 PHE B 404
REMARK 465 ASP B 405
REMARK 465 ASN B 406
REMARK 465 PRO B 407
REMARK 465 ALA B 408
REMARK 465 ASP B 439
REMARK 465 LEU B 440
REMARK 465 THR B 441
REMARK 465 GLY B 442
REMARK 465 PHE B 443
REMARK 465 GLU B 444
REMARK 465 GLU B 445
REMARK 465 GLU B 446
REMARK 465 GLU B 447
REMARK 465 GLU B 448
REMARK 465 ALA B 449
REMARK 465 VAL B 450
REMARK 465 LYS B 451
REMARK 465 ASP B 452
REMARK 465 HIS B 453
REMARK 465 PRO B 454
REMARK 465 ARG B 455
REMARK 465 ALA B 456
REMARK 465 GLU B 457
REMARK 465 TYR B 458
REMARK 465 GLU B 459
REMARK 465 ALA B 460
REMARK 465 ARG B 461
REMARK 465 VAL B 462
REMARK 465 LEU B 463
REMARK 465 GLU B 464
REMARK 465 LYS B 465
REMARK 465 SER B 466
REMARK 465 LEU B 467
REMARK 465 ARG B 468
REMARK 465 LYS B 469
REMARK 465 GLU B 470
REMARK 465 SER B 471
REMARK 465 ARG B 472
REMARK 465 ASN B 473
REMARK 465 LYS B 474
REMARK 465 GLU B 475
REMARK 465 THR B 476
REMARK 465 ASP B 477
REMARK 465 LYS B 478
REMARK 465 VAL B 479
REMARK 465 LYS B 480
REMARK 465 LEU B 481
REMARK 465 THR B 482
REMARK 465 TRP B 483
REMARK 465 ARG B 484
REMARK 465 ASP B 485
REMARK 465 ALA B 521
REMARK 465 LEU B 522
REMARK 465 ALA B 523
REMARK 465 MET B 524
REMARK 465 ASN B 525
REMARK 465 SER B 526
REMARK 465 SER B 527
REMARK 465 PRO B 528
REMARK 465 SER B 529
REMARK 465 VAL B 530
REMARK 465 ARG B 531
REMARK 465 SER B 532
REMARK 465 ASN B 533
REMARK 465 ILE B 534
REMARK 465 LYS B 603
REMARK 465 GLY B 604
REMARK 465 ARG B 605
REMARK 465 PHE B 606
REMARK 465 VAL B 607
REMARK 465 GLY B 608
REMARK 465 ARG B 609
REMARK 465 PRO B 610
REMARK 465 GLY B 611
REMARK 465 ASP B 612
REMARK 465 TYR B 613
REMARK 465 VAL B 614
REMARK 465 TYR B 615
REMARK 465 ILE B 616
REMARK 465 PHE B 617
REMARK 465 ARG B 618
REMARK 465 SER B 619
REMARK 465 PHE B 620
REMARK 465 ARG B 621
REMARK 465 MET B 622
REMARK 465 GLU B 623
REMARK 465 GLU B 624
REMARK 465 CYS B 625
REMARK 465 ALA B 626
REMARK 465 PRO B 627
REMARK 465 GLY B 628
REMARK 465 GLY B 629
REMARK 465 CYS B 630
REMARK 465 LEU B 631
REMARK 465 MET B 632
REMARK 465 LEU B 667
REMARK 465 LYS B 668
REMARK 465 LEU B 669
REMARK 465 ARG B 670
REMARK 465 ARG B 671
REMARK 465 GLN B 672
REMARK 465 SER B 673
REMARK 465 PRO B 674
REMARK 465 SER B 675
REMARK 465 ASP B 676
REMARK 465 ARG B 677
REMARK 465 GLU B 678
REMARK 465 GLU B 679
REMARK 465 TYR B 680
REMARK 465 LEU B 693
REMARK 465 GLU B 694
REMARK 465 PRO B 695
REMARK 465 PHE B 696
REMARK 465 THR B 782
REMARK 465 SER B 783
REMARK 465 ASP B 784
REMARK 465 PHE B 785
REMARK 465 ILE B 786
REMARK 465 PRO B 787
REMARK 465 ARG B 788
REMARK 465 LEU B 789
REMARK 465 VAL B 790
REMARK 465 TYR B 791
REMARK 465 LEU B 792
REMARK 465 TYR B 793
REMARK 465 MET B 794
REMARK 465 TYR B 795
REMARK 465 SER B 796
REMARK 465 GLN B 797
REMARK 465 ASN B 798
REMARK 465 GLY B 799
REMARK 465 THR B 800
REMARK 465 MET B 801
REMARK 465 HIS B 802
REMARK 465 GLY B 803
REMARK 465 PHE B 804
REMARK 465 VAL B 805
REMARK 465 ASN B 806
REMARK 465 HIS B 807
REMARK 465 THR B 808
REMARK 465 LEU B 809
REMARK 465 SER B 810
REMARK 465 SER B 811
REMARK 465 PHE B 812
REMARK 465 ASN B 813
REMARK 465 VAL B 814
REMARK 465 SER B 815
REMARK 465 ASP B 816
REMARK 465 PHE B 817
REMARK 465 GLN B 818
REMARK 465 ASN B 819
REMARK 465 GLY B 820
REMARK 465 THR B 821
REMARK 465 ALA B 822
REMARK 465 PRO B 823
REMARK 465 ASN B 824
REMARK 465 ASP B 825
REMARK 465 PRO B 826
REMARK 465 LEU B 827
REMARK 465 ASP B 828
REMARK 465 LEU B 829
REMARK 465 GLY B 830
REMARK 465 TYR B 831
REMARK 465 GLU B 832
REMARK 465 VAL B 833
REMARK 465 GLN B 834
REMARK 465 ILE B 835
REMARK 465 CYS B 836
REMARK 465 ARG B 837
REMARK 465 TYR B 838
REMARK 465 LYS B 839
REMARK 465 ASP B 840
REMARK 465 TYR B 841
REMARK 465 ARG B 842
REMARK 465 GLU B 843
REMARK 465 PRO B 844
REMARK 465 PRO B 845
REMARK 465 TRP B 846
REMARK 465 SER B 847
REMARK 465 GLU B 848
REMARK 465 HIS B 849
REMARK 465 LYS B 850
REMARK 465 TYR B 851
REMARK 465 ASP B 852
REMARK 465 ILE B 853
REMARK 465 SER B 854
REMARK 465 ILE B 886
REMARK 465 PRO B 887
REMARK 465 ASP B 888
REMARK 465 ILE B 889
REMARK 465 PRO B 890
REMARK 465 LYS B 891
REMARK 465 ARG B 910
REMARK 465 GLU B 911
REMARK 465 GLU B 912
REMARK 465 GLN B 913
REMARK 465 GLY B 914
REMARK 465 LYS B 915
REMARK 465 GLN B 916
REMARK 465 GLN B 917
REMARK 465 LEU B 918
REMARK 465 LEU B 919
REMARK 465 ASP B 920
REMARK 465 THR B 921
REMARK 465 TRP B 922
REMARK 465 MET B 923
REMARK 465 GLU B 924
REMARK 465 LYS B 925
REMARK 465 GLU B 926
REMARK 465 LYS B 927
REMARK 465 PRO B 928
REMARK 465 ARG B 929
REMARK 465 ASP B 930
REMARK 465 VAL B 931
REMARK 465 PRO B 932
REMARK 465 CYS B 933
REMARK 465 ASN B 934
REMARK 465 ASN B 935
REMARK 465 HIS B 936
REMARK 465 SER B 937
REMARK 465 PRO B 938
REMARK 465 THR B 939
REMARK 465 THR B 940
REMARK 465 HIS B 941
REMARK 465 PRO B 942
REMARK 465 GLU B 943
REMARK 465 ALA B 944
REMARK 465 GLY B 945
REMARK 465 ASP B 946
REMARK 465 GLY B 947
REMARK 465 SER B 948
REMARK 465 PRO B 949
REMARK 465 VAL B 950
REMARK 465 PRO B 951
REMARK 465 SER B 952
REMARK 465 TYR B 953
REMARK 465 GLU B 954
REMARK 465 TYR B 955
REMARK 465 HIS B 956
REMARK 465 GLY B 957
REMARK 465 ASP B 958
REMARK 465 ALA B 959
REMARK 465 LEU B 960
REMARK 470
REMARK 470 MISSING ATOM
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;
REMARK 470 I=INSERTION CODE):
REMARK 470 M RES CSSEQI ATOMS
REMARK 470 ASP A 123 CG OD1 OD2
REMARK 470 LYS A 124 CG CD CE NZ
REMARK 470 ARG A 125 CG CD NE CZ NH1 NH2
REMARK 470 PHE A 126 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 ARG A 127 CG CD NE CZ NH1 NH2
REMARK 470 ARG A 167 CG CD NE CZ NH1 NH2
REMARK 470 GLU A 168 CG CD OE1 OE2
REMARK 470 GLU A 170 CG CD OE1 OE2
REMARK 470 PHE A 171 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 LEU A 172 CG CD1 CD2
REMARK 470 LYS A 173 CG CD CE NZ
REMARK 470 LEU A 174 CG CD1 CD2
REMARK 470 LYS A 175 CG CD CE NZ
REMARK 470 MET A 176 CG SD CE
REMARK 470 PRO A 177 CG CD
REMARK 470 THR A 178 OG1 CG2
REMARK 470 LYS A 179 CG CD CE NZ
REMARK 470 LYS A 180 CG CD CE NZ
REMARK 470 VAL A 181 CG1 CG2
REMARK 470 TYR A 182 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 HIS A 183 CG ND1 CD2 CE1 NE2
REMARK 470 ILE A 184 CG1 CG2 CD1
REMARK 470 SER A 185 OG
REMARK 470 GLU A 186 CG CD OE1 OE2
REMARK 470 THR A 187 OG1 CG2
REMARK 470 ARG A 188 CG CD NE CZ NH1 NH2
REMARK 470 LEU A 190 CG CD1 CD2
REMARK 470 LEU A 191 CG CD1 CD2
REMARK 470 LYS A 192 CG CD CE NZ
REMARK 470 THR A 193 OG1 CG2
REMARK 470 ILE A 194 CG1 CG2 CD1
REMARK 470 ASN A 195 CG OD1 ND2
REMARK 470 SER A 196 OG
REMARK 470 VAL A 197 CG1 CG2
REMARK 470 LEU A 198 CG CD1 CD2
REMARK 470 GLN A 199 CG CD OE1 NE2
REMARK 470 LYS A 200 CG CD CE NZ
REMARK 470 ILE A 201 CG1 CG2 CD1
REMARK 470 PRO A 204 CG CD
REMARK 470 ILE A 205 CG1 CG2 CD1
REMARK 470 GLN A 206 CG CD OE1 NE2
REMARK 470 PRO A 207 CG CD
REMARK 470 LYS A 208 CG CD CE NZ
REMARK 470 VAL A 209 CG1 CG2
REMARK 470 GLU A 211 CG CD OE1 OE2
REMARK 470 HIS A 212 CG ND1 CD2 CE1 NE2
REMARK 470 ARG A 213 CG CD NE CZ NH1 NH2
REMARK 470 PRO A 214 CG CD
REMARK 470 ASP A 242 CG OD1 OD2
REMARK 470 SER A 243 OG
REMARK 470 LYS A 244 CG CD CE NZ
REMARK 470 THR A 245 OG1 CG2
REMARK 470 ARG A 246 CG CD NE CZ NH1 NH2
REMARK 470 SER A 247 OG
REMARK 470 THR A 248 OG1 CG2
REMARK 470 ILE A 249 CG1 CG2 CD1
REMARK 470 VAL A 250 CG1 CG2
REMARK 470 TYR A 251 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 GLU A 252 CG CD OE1 OE2
REMARK 470 ILE A 253 CG1 CG2 CD1
REMARK 470 LEU A 254 CG CD1 CD2
REMARK 470 SER A 278 OG
REMARK 470 TYR A 281 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 PRO A 282 CG CD
REMARK 470 PHE A 295 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 ASN A 296 CG OD1 ND2
REMARK 470 ASP A 297 CG OD1 OD2
REMARK 470 ARG A 298 CG CD NE CZ NH1 NH2
REMARK 470 LYS A 299 CG CD CE NZ
REMARK 470 LEU A 300 CG CD1 CD2
REMARK 470 LEU A 301 CG CD1 CD2
REMARK 470 TYR A 302 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 GLU A 303 CG CD OE1 OE2
REMARK 470 GLU A 304 CG CD OE1 OE2
REMARK 470 TRP A 305 CG CD1 CD2 NE1 CE2 CE3 CZ2
REMARK 470 TRP A 305 CZ3 CH2
REMARK 470 GLN A 315 CG CD OE1 NE2
REMARK 470 PRO A 316 CG CD
REMARK 470 ILE A 317 CG1 CG2 CD1
REMARK 470 ASP A 318 CG OD1 OD2
REMARK 470 LEU A 319 CG CD1 CD2
REMARK 470 VAL A 320 CG1 CG2
REMARK 470 ARG A 321 CG CD NE CZ NH1 NH2
REMARK 470 LYS A 322 CG CD CE NZ
REMARK 470 TYR A 323 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 PHE A 324 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 GLU A 326 CG CD OE1 OE2
REMARK 470 LYS A 327 CG CD CE NZ
REMARK 470 VAL A 328 CG1 CG2
REMARK 470 LEU A 330 CG CD1 CD2
REMARK 470 TYR A 331 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 PHE A 332 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 TRP A 334 CG CD1 CD2 NE1 CE2 CE3 CZ2
REMARK 470 TRP A 334 CZ3 CH2
REMARK 470 LEU A 335 CG CD1 CD2
REMARK 470 TYR A 338 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 THR A 339 OG1 CG2
REMARK 470 GLN A 340 CG CD OE1 NE2
REMARK 470 MET A 341 CG SD CE
REMARK 470 LEU A 342 CG CD1 CD2
REMARK 470 ILE A 343 CG1 CG2 CD1
REMARK 470 PRO A 344 CG CD
REMARK 470 SER A 346 OG
REMARK 470 ILE A 347 CG1 CG2 CD1
REMARK 470 VAL A 348 CG1 CG2
REMARK 470 VAL A 350 CG1 CG2
REMARK 470 ILE A 351 CG1 CG2 CD1
REMARK 470 VAL A 352 CG1 CG2
REMARK 470 PHE A 353 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 LEU A 354 CG CD1 CD2
REMARK 470 TYR A 355 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 THR A 409 OG1 CG2
REMARK 470 VAL A 410 CG1 CG2
REMARK 470 PHE A 411 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 PHE A 412 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 SER A 413 OG
REMARK 470 VAL A 414 CG1 CG2
REMARK 470 PHE A 415 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 MET A 416 CG SD CE
REMARK 470 LEU A 418 CG CD1 CD2
REMARK 470 TRP A 419 CG CD1 CD2 NE1 CE2 CE3 CZ2
REMARK 470 TRP A 419 CZ3 CH2
REMARK 470 THR A 422 OG1 CG2
REMARK 470 PHE A 423 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 MET A 424 CG SD CE
REMARK 470 GLU A 425 CG CD OE1 OE2
REMARK 470 HIS A 426 CG ND1 CD2 CE1 NE2
REMARK 470 TRP A 427 CG CD1 CD2 NE1 CE2 CE3 CZ2
REMARK 470 TRP A 427 CZ3 CH2
REMARK 470 LYS A 428 CG CD CE NZ
REMARK 470 ARG A 429 CG CD NE CZ NH1 NH2
REMARK 470 LYS A 430 CG CD CE NZ
REMARK 470 GLN A 431 CG CD OE1 NE2
REMARK 470 MET A 432 CG SD CE
REMARK 470 ARG A 433 CG CD NE CZ NH1 NH2
REMARK 470 LEU A 434 CG CD1 CD2
REMARK 470 ASN A 435 CG OD1 ND2
REMARK 470 TYR A 436 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 ARG A 437 CG CD NE CZ NH1 NH2
REMARK 470 TRP A 438 CG CD1 CD2 NE1 CE2 CE3 CZ2
REMARK 470 TRP A 438 CZ3 CH2
REMARK 470 ARG A 486 CG CD NE CZ NH1 NH2
REMARK 470 PHE A 487 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 PRO A 488 CG CD
REMARK 470 TYR A 490 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 PHE A 491 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 THR A 492 OG1 CG2
REMARK 470 ASN A 493 CG OD1 ND2
REMARK 470 LEU A 494 CG CD1 CD2
REMARK 470 VAL A 495 CG1 CG2
REMARK 470 SER A 496 OG
REMARK 470 ILE A 497 CG1 CG2 CD1
REMARK 470 ILE A 498 CG1 CG2 CD1
REMARK 470 PHE A 499 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 MET A 500 CG SD CE
REMARK 470 ILE A 501 CG1 CG2 CD1
REMARK 470 VAL A 503 CG1 CG2
REMARK 470 THR A 504 OG1 CG2
REMARK 470 PHE A 505 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 ILE A 507 CG1 CG2 CD1
REMARK 470 VAL A 508 CG1 CG2
REMARK 470 LEU A 509 CG CD1 CD2
REMARK 470 VAL A 511 CG1 CG2
REMARK 470 ILE A 512 CG1 CG2 CD1
REMARK 470 ILE A 513 CG1 CG2 CD1
REMARK 470 TYR A 514 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 ARG A 515 CG CD NE CZ NH1 NH2
REMARK 470 ILE A 516 CG1 CG2 CD1
REMARK 470 SER A 517 OG
REMARK 470 THR A 518 OG1 CG2
REMARK 470 ARG A 535 CG CD NE CZ NH1 NH2
REMARK 470 VAL A 536 CG1 CG2
REMARK 470 THR A 537 OG1 CG2
REMARK 470 VAL A 538 CG1 CG2
REMARK 470 THR A 539 OG1 CG2
REMARK 470 THR A 541 OG1 CG2
REMARK 470 VAL A 543 CG1 CG2
REMARK 470 ILE A 544 CG1 CG2 CD1
REMARK 470 ILE A 545 CG1 CG2 CD1
REMARK 470 ASN A 546 CG OD1 ND2
REMARK 470 LEU A 547 CG CD1 CD2
REMARK 470 VAL A 548 CG1 CG2
REMARK 470 VAL A 549 CG1 CG2
REMARK 470 ILE A 550 CG1 CG2 CD1
REMARK 470 ILE A 551 CG1 CG2 CD1
REMARK 470 LEU A 552 CG CD1 CD2
REMARK 470 LEU A 553 CG CD1 CD2
REMARK 470 ASP A 554 CG OD1 OD2
REMARK 470 GLU A 555 CG CD OE1 OE2
REMARK 470 VAL A 556 CG1 CG2
REMARK 470 TYR A 557 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 CYS A 559 SG
REMARK 470 ILE A 560 CG1 CG2 CD1
REMARK 470 ARG A 562 CG CD NE CZ NH1 NH2
REMARK 470 TRP A 563 CG CD1 CD2 NE1 CE2 CE3 CZ2
REMARK 470 TRP A 563 CZ3 CH2
REMARK 470 LEU A 564 CG CD1 CD2
REMARK 470 THR A 565 OG1 CG2
REMARK 470 LYS A 566 CG CD CE NZ
REMARK 470 ILE A 567 CG1 CG2 CD1
REMARK 470 GLU A 568 CG CD OE1 OE2
REMARK 470 VAL A 569 CG1 CG2
REMARK 470 PRO A 570 CG CD
REMARK 470 LYS A 571 CG CD CE NZ
REMARK 470 THR A 572 OG1 CG2
REMARK 470 GLU A 573 CG CD OE1 OE2
REMARK 470 LYS A 574 CG CD CE NZ
REMARK 470 SER A 575 OG
REMARK 470 PHE A 576 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 GLU A 577 CG CD OE1 OE2
REMARK 470 GLU A 578 CG CD OE1 OE2
REMARK 470 ARG A 579 CG CD NE CZ NH1 NH2
REMARK 470 LEU A 580 CG CD1 CD2
REMARK 470 THR A 581 OG1 CG2
REMARK 470 PHE A 582 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 LYS A 583 CG CD CE NZ
REMARK 470 PHE A 585 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 LEU A 586 CG CD1 CD2
REMARK 470 LEU A 587 CG CD1 CD2
REMARK 470 LYS A 588 CG CD CE NZ
REMARK 470 PHE A 589 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 VAL A 590 CG1 CG2
REMARK 470 ASN A 591 CG OD1 ND2
REMARK 470 SER A 592 OG
REMARK 470 TYR A 593 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 THR A 594 OG1 CG2
REMARK 470 PRO A 595 CG CD
REMARK 470 ILE A 596 CG1 CG2 CD1
REMARK 470 PHE A 597 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 TYR A 598 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 VAL A 599 CG1 CG2
REMARK 470 PHE A 601 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 PHE A 602 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 GLU A 633 CG CD OE1 OE2
REMARK 470 LEU A 634 CG CD1 CD2
REMARK 470 CYS A 635 SG
REMARK 470 ILE A 636 CG1 CG2 CD1
REMARK 470 GLN A 637 CG CD OE1 NE2
REMARK 470 LEU A 638 CG CD1 CD2
REMARK 470 SER A 639 OG
REMARK 470 ILE A 640 CG1 CG2 CD1
REMARK 470 ILE A 641 CG1 CG2 CD1
REMARK 470 MET A 642 CG SD CE
REMARK 470 LEU A 643 CG CD1 CD2
REMARK 470 LYS A 645 CG CD CE NZ
REMARK 470 GLN A 646 CG CD OE1 NE2
REMARK 470 LEU A 647 CG CD1 CD2
REMARK 470 ILE A 648 CG1 CG2 CD1
REMARK 470 GLN A 649 CG CD OE1 NE2
REMARK 470 ASN A 650 CG OD1 ND2
REMARK 470 ASN A 651 CG OD1 ND2
REMARK 470 LEU A 652 CG CD1 CD2
REMARK 470 PHE A 653 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 GLU A 654 CG CD OE1 OE2
REMARK 470 ILE A 655 CG1 CG2 CD1
REMARK 470 ILE A 657 CG1 CG2 CD1
REMARK 470 PRO A 658 CG CD
REMARK 470 LYS A 659 CG CD CE NZ
REMARK 470 MET A 660 CG SD CE
REMARK 470 LYS A 661 CG CD CE NZ
REMARK 470 LYS A 662 CG CD CE NZ
REMARK 470 PHE A 663 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 ILE A 664 CG1 CG2 CD1
REMARK 470 ARG A 665 CG CD NE CZ NH1 NH2
REMARK 470 TYR A 666 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 VAL A 681 CG1 CG2
REMARK 470 LYS A 682 CG CD CE NZ
REMARK 470 ARG A 683 CG CD NE CZ NH1 NH2
REMARK 470 LYS A 684 CG CD CE NZ
REMARK 470 GLN A 685 CG CD OE1 NE2
REMARK 470 ARG A 686 CG CD NE CZ NH1 NH2
REMARK 470 TYR A 687 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 GLU A 688 CG CD OE1 OE2
REMARK 470 VAL A 689 CG1 CG2
REMARK 470 ASP A 690 CG OD1 OD2
REMARK 470 PHE A 691 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 ASN A 692 CG OD1 ND2
REMARK 470 LEU A 699 CG CD1 CD2
REMARK 470 THR A 700 OG1 CG2
REMARK 470 PRO A 701 CG CD
REMARK 470 GLU A 702 CG CD OE1 OE2
REMARK 470 TYR A 703 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 MET A 704 CG SD CE
REMARK 470 GLU A 705 CG CD OE1 OE2
REMARK 470 MET A 706 CG SD CE
REMARK 470 ILE A 707 CG1 CG2 CD1
REMARK 470 ILE A 708 CG1 CG2 CD1
REMARK 470 GLN A 709 CG CD OE1 NE2
REMARK 470 PHE A 710 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 PHE A 712 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 VAL A 713 CG1 CG2
REMARK 470 THR A 714 OG1 CG2
REMARK 470 LEU A 715 CG CD1 CD2
REMARK 470 PHE A 716 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 VAL A 717 CG1 CG2
REMARK 470 SER A 719 OG
REMARK 470 PHE A 720 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 PRO A 721 CG CD
REMARK 470 LEU A 722 CG CD1 CD2
REMARK 470 PRO A 724 CG CD
REMARK 470 LEU A 725 CG CD1 CD2
REMARK 470 PHE A 726 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 LEU A 728 CG CD1 CD2
REMARK 470 LEU A 729 CG CD1 CD2
REMARK 470 ASN A 730 CG OD1 ND2
REMARK 470 ASN A 731 CG OD1 ND2
REMARK 470 ILE A 732 CG1 CG2 CD1
REMARK 470 ILE A 733 CG1 CG2 CD1
REMARK 470 GLU A 734 CG CD OE1 OE2
REMARK 470 ILE A 735 CG1 CG2 CD1
REMARK 470 ARG A 736 CG CD NE CZ NH1 NH2
REMARK 470 LEU A 737 CG CD1 CD2
REMARK 470 ASP A 738 CG OD1 OD2
REMARK 470 LYS A 740 CG CD CE NZ
REMARK 470 LYS A 741 CG CD CE NZ
REMARK 470 PHE A 742 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 VAL A 743 CG1 CG2
REMARK 470 THR A 744 OG1 CG2
REMARK 470 GLU A 745 CG CD OE1 OE2
REMARK 470 LEU A 746 CG CD1 CD2
REMARK 470 ARG A 747 CG CD NE CZ NH1 NH2
REMARK 470 ARG A 748 CG CD NE CZ NH1 NH2
REMARK 470 PRO A 749 CG CD
REMARK 470 VAL A 750 CG1 CG2
REMARK 470 ILE A 752 CG1 CG2 CD1
REMARK 470 ARG A 753 CG CD NE CZ NH1 NH2
REMARK 470 LYS A 755 CG CD CE NZ
REMARK 470 ASP A 756 CG OD1 OD2
REMARK 470 ILE A 757 CG1 CG2 CD1
REMARK 470 ILE A 759 CG1 CG2 CD1
REMARK 470 TRP A 760 CG CD1 CD2 NE1 CE2 CE3 CZ2
REMARK 470 TRP A 760 CZ3 CH2
REMARK 470 TYR A 761 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 ASN A 762 CG OD1 ND2
REMARK 470 ILE A 763 CG1 CG2 CD1
REMARK 470 LEU A 764 CG CD1 CD2
REMARK 470 ARG A 765 CG CD NE CZ NH1 NH2
REMARK 470 VAL A 767 CG1 CG2
REMARK 470 LYS A 769 CG CD CE NZ
REMARK 470 LEU A 770 CG CD1 CD2
REMARK 470 VAL A 772 CG1 CG2
REMARK 470 ILE A 773 CG1 CG2 CD1
REMARK 470 ILE A 774 CG1 CG2 CD1
REMARK 470 ASN A 775 CG OD1 ND2
REMARK 470 PHE A 777 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 VAL A 778 CG1 CG2
REMARK 470 ILE A 779 CG1 CG2 CD1
REMARK 470 SER A 780 OG
REMARK 470 PHE A 781 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 LYS A 855 CG CD CE NZ
REMARK 470 ASP A 856 CG OD1 OD2
REMARK 470 PHE A 857 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 TRP A 858 CG CD1 CD2 NE1 CE2 CE3 CZ2
REMARK 470 TRP A 858 CZ3 CH2
REMARK 470 VAL A 860 CG1 CG2
REMARK 470 LEU A 861 CG CD1 CD2
REMARK 470 ARG A 864 CG CD NE CZ NH1 NH2
REMARK 470 LEU A 865 CG CD1 CD2
REMARK 470 PHE A 867 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 VAL A 868 CG1 CG2
REMARK 470 ILE A 869 CG1 CG2 CD1
REMARK 470 VAL A 870 CG1 CG2
REMARK 470 PHE A 871 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 GLN A 872 CG CD OE1 NE2
REMARK 470 ASN A 873 CG OD1 ND2
REMARK 470 LEU A 874 CG CD1 CD2
REMARK 470 VAL A 875 CG1 CG2
REMARK 470 MET A 876 CG SD CE
REMARK 470 PHE A 877 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 MET A 878 CG SD CE
REMARK 470 SER A 879 OG
REMARK 470 ASP A 880 CG OD1 OD2
REMARK 470 PHE A 881 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 VAL A 882 CG1 CG2
REMARK 470 ASP A 883 CG OD1 OD2
REMARK 470 TRP A 884 CG CD1 CD2 NE1 CE2 CE3 CZ2
REMARK 470 TRP A 884 CZ3 CH2
REMARK 470 VAL A 885 CG1 CG2
REMARK 470 ASP A 892 CG OD1 OD2
REMARK 470 ILE A 893 CG1 CG2 CD1
REMARK 470 SER A 894 OG
REMARK 470 GLN A 895 CG CD OE1 NE2
REMARK 470 GLN A 896 CG CD OE1 NE2
REMARK 470 ILE A 897 CG1 CG2 CD1
REMARK 470 HIS A 898 CG ND1 CD2 CE1 NE2
REMARK 470 LYS A 899 CG CD CE NZ
REMARK 470 GLU A 900 CG CD OE1 OE2
REMARK 470 LYS A 901 CG CD CE NZ
REMARK 470 VAL A 902 CG1 CG2
REMARK 470 LEU A 903 CG CD1 CD2
REMARK 470 MET A 904 CG SD CE
REMARK 470 VAL A 905 CG1 CG2
REMARK 470 GLU A 906 CG CD OE1 OE2
REMARK 470 LEU A 907 CG CD1 CD2
REMARK 470 PHE A 908 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 MET A 909 CG SD CE
REMARK 470 ASP B 123 CG OD1 OD2
REMARK 470 LYS B 124 CG CD CE NZ
REMARK 470 ARG B 125 CG CD NE CZ NH1 NH2
REMARK 470 PHE B 126 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 ARG B 127 CG CD NE CZ NH1 NH2
REMARK 470 ARG B 167 CG CD NE CZ NH1 NH2
REMARK 470 GLU B 168 CG CD OE1 OE2
REMARK 470 GLU B 170 CG CD OE1 OE2
REMARK 470 PHE B 171 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 LEU B 172 CG CD1 CD2
REMARK 470 LYS B 173 CG CD CE NZ
REMARK 470 LEU B 174 CG CD1 CD2
REMARK 470 LYS B 175 CG CD CE NZ
REMARK 470 MET B 176 CG SD CE
REMARK 470 PRO B 177 CG CD
REMARK 470 THR B 178 OG1 CG2
REMARK 470 LYS B 179 CG CD CE NZ
REMARK 470 LYS B 180 CG CD CE NZ
REMARK 470 VAL B 181 CG1 CG2
REMARK 470 TYR B 182 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 HIS B 183 CG ND1 CD2 CE1 NE2
REMARK 470 ILE B 184 CG1 CG2 CD1
REMARK 470 SER B 185 OG
REMARK 470 GLU B 186 CG CD OE1 OE2
REMARK 470 THR B 187 OG1 CG2
REMARK 470 ARG B 188 CG CD NE CZ NH1 NH2
REMARK 470 LEU B 190 CG CD1 CD2
REMARK 470 LEU B 191 CG CD1 CD2
REMARK 470 LYS B 192 CG CD CE NZ
REMARK 470 THR B 193 OG1 CG2
REMARK 470 ILE B 194 CG1 CG2 CD1
REMARK 470 ASN B 195 CG OD1 ND2
REMARK 470 SER B 196 OG
REMARK 470 VAL B 197 CG1 CG2
REMARK 470 LEU B 198 CG CD1 CD2
REMARK 470 GLN B 199 CG CD OE1 NE2
REMARK 470 LYS B 200 CG CD CE NZ
REMARK 470 ILE B 201 CG1 CG2 CD1
REMARK 470 PRO B 204 CG CD
REMARK 470 ILE B 205 CG1 CG2 CD1
REMARK 470 GLN B 206 CG CD OE1 NE2
REMARK 470 PRO B 207 CG CD
REMARK 470 LYS B 208 CG CD CE NZ
REMARK 470 VAL B 209 CG1 CG2
REMARK 470 GLU B 211 CG CD OE1 OE2
REMARK 470 HIS B 212 CG ND1 CD2 CE1 NE2
REMARK 470 ARG B 213 CG CD NE CZ NH1 NH2
REMARK 470 PRO B 214 CG CD
REMARK 470 ASP B 242 CG OD1 OD2
REMARK 470 SER B 243 OG
REMARK 470 LYS B 244 CG CD CE NZ
REMARK 470 THR B 245 OG1 CG2
REMARK 470 ARG B 246 CG CD NE CZ NH1 NH2
REMARK 470 SER B 247 OG
REMARK 470 THR B 248 OG1 CG2
REMARK 470 ILE B 249 CG1 CG2 CD1
REMARK 470 VAL B 250 CG1 CG2
REMARK 470 TYR B 251 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 GLU B 252 CG CD OE1 OE2
REMARK 470 ILE B 253 CG1 CG2 CD1
REMARK 470 LEU B 254 CG CD1 CD2
REMARK 470 SER B 278 OG
REMARK 470 TYR B 281 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 PRO B 282 CG CD
REMARK 470 PHE B 295 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 ASN B 296 CG OD1 ND2
REMARK 470 ASP B 297 CG OD1 OD2
REMARK 470 ARG B 298 CG CD NE CZ NH1 NH2
REMARK 470 LYS B 299 CG CD CE NZ
REMARK 470 LEU B 300 CG CD1 CD2
REMARK 470 LEU B 301 CG CD1 CD2
REMARK 470 TYR B 302 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 GLU B 303 CG CD OE1 OE2
REMARK 470 GLU B 304 CG CD OE1 OE2
REMARK 470 TRP B 305 CG CD1 CD2 NE1 CE2 CE3 CZ2
REMARK 470 TRP B 305 CZ3 CH2
REMARK 470 GLN B 315 CG CD OE1 NE2
REMARK 470 PRO B 316 CG CD
REMARK 470 ILE B 317 CG1 CG2 CD1
REMARK 470 ASP B 318 CG OD1 OD2
REMARK 470 LEU B 319 CG CD1 CD2
REMARK 470 VAL B 320 CG1 CG2
REMARK 470 ARG B 321 CG CD NE CZ NH1 NH2
REMARK 470 LYS B 322 CG CD CE NZ
REMARK 470 TYR B 323 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 PHE B 324 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 GLU B 326 CG CD OE1 OE2
REMARK 470 LYS B 327 CG CD CE NZ
REMARK 470 VAL B 328 CG1 CG2
REMARK 470 LEU B 330 CG CD1 CD2
REMARK 470 TYR B 331 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 PHE B 332 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 TRP B 334 CG CD1 CD2 NE1 CE2 CE3 CZ2
REMARK 470 TRP B 334 CZ3 CH2
REMARK 470 LEU B 335 CG CD1 CD2
REMARK 470 TYR B 338 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 THR B 339 OG1 CG2
REMARK 470 GLN B 340 CG CD OE1 NE2
REMARK 470 MET B 341 CG SD CE
REMARK 470 LEU B 342 CG CD1 CD2
REMARK 470 ILE B 343 CG1 CG2 CD1
REMARK 470 PRO B 344 CG CD
REMARK 470 SER B 346 OG
REMARK 470 ILE B 347 CG1 CG2 CD1
REMARK 470 VAL B 348 CG1 CG2
REMARK 470 VAL B 350 CG1 CG2
REMARK 470 ILE B 351 CG1 CG2 CD1
REMARK 470 VAL B 352 CG1 CG2
REMARK 470 PHE B 353 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 LEU B 354 CG CD1 CD2
REMARK 470 TYR B 355 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 THR B 409 OG1 CG2
REMARK 470 VAL B 410 CG1 CG2
REMARK 470 PHE B 411 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 PHE B 412 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 SER B 413 OG
REMARK 470 VAL B 414 CG1 CG2
REMARK 470 PHE B 415 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 MET B 416 CG SD CE
REMARK 470 LEU B 418 CG CD1 CD2
REMARK 470 TRP B 419 CG CD1 CD2 NE1 CE2 CE3 CZ2
REMARK 470 TRP B 419 CZ3 CH2
REMARK 470 THR B 422 OG1 CG2
REMARK 470 PHE B 423 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 MET B 424 CG SD CE
REMARK 470 GLU B 425 CG CD OE1 OE2
REMARK 470 HIS B 426 CG ND1 CD2 CE1 NE2
REMARK 470 TRP B 427 CG CD1 CD2 NE1 CE2 CE3 CZ2
REMARK 470 TRP B 427 CZ3 CH2
REMARK 470 LYS B 428 CG CD CE NZ
REMARK 470 ARG B 429 CG CD NE CZ NH1 NH2
REMARK 470 LYS B 430 CG CD CE NZ
REMARK 470 GLN B 431 CG CD OE1 NE2
REMARK 470 MET B 432 CG SD CE
REMARK 470 ARG B 433 CG CD NE CZ NH1 NH2
REMARK 470 LEU B 434 CG CD1 CD2
REMARK 470 ASN B 435 CG OD1 ND2
REMARK 470 TYR B 436 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 ARG B 437 CG CD NE CZ NH1 NH2
REMARK 470 TRP B 438 CG CD1 CD2 NE1 CE2 CE3 CZ2
REMARK 470 TRP B 438 CZ3 CH2
REMARK 470 ARG B 486 CG CD NE CZ NH1 NH2
REMARK 470 PHE B 487 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 PRO B 488 CG CD
REMARK 470 TYR B 490 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 PHE B 491 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 THR B 492 OG1 CG2
REMARK 470 ASN B 493 CG OD1 ND2
REMARK 470 LEU B 494 CG CD1 CD2
REMARK 470 VAL B 495 CG1 CG2
REMARK 470 SER B 496 OG
REMARK 470 ILE B 497 CG1 CG2 CD1
REMARK 470 ILE B 498 CG1 CG2 CD1
REMARK 470 PHE B 499 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 MET B 500 CG SD CE
REMARK 470 ILE B 501 CG1 CG2 CD1
REMARK 470 VAL B 503 CG1 CG2
REMARK 470 THR B 504 OG1 CG2
REMARK 470 PHE B 505 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 ILE B 507 CG1 CG2 CD1
REMARK 470 VAL B 508 CG1 CG2
REMARK 470 LEU B 509 CG CD1 CD2
REMARK 470 VAL B 511 CG1 CG2
REMARK 470 ILE B 512 CG1 CG2 CD1
REMARK 470 ILE B 513 CG1 CG2 CD1
REMARK 470 TYR B 514 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 ARG B 515 CG CD NE CZ NH1 NH2
REMARK 470 ILE B 516 CG1 CG2 CD1
REMARK 470 SER B 517 OG
REMARK 470 THR B 518 OG1 CG2
REMARK 470 ARG B 535 CG CD NE CZ NH1 NH2
REMARK 470 VAL B 536 CG1 CG2
REMARK 470 THR B 537 OG1 CG2
REMARK 470 VAL B 538 CG1 CG2
REMARK 470 THR B 539 OG1 CG2
REMARK 470 THR B 541 OG1 CG2
REMARK 470 VAL B 543 CG1 CG2
REMARK 470 ILE B 544 CG1 CG2 CD1
REMARK 470 ILE B 545 CG1 CG2 CD1
REMARK 470 ASN B 546 CG OD1 ND2
REMARK 470 LEU B 547 CG CD1 CD2
REMARK 470 VAL B 548 CG1 CG2
REMARK 470 VAL B 549 CG1 CG2
REMARK 470 ILE B 550 CG1 CG2 CD1
REMARK 470 ILE B 551 CG1 CG2 CD1
REMARK 470 LEU B 552 CG CD1 CD2
REMARK 470 LEU B 553 CG CD1 CD2
REMARK 470 ASP B 554 CG OD1 OD2
REMARK 470 GLU B 555 CG CD OE1 OE2
REMARK 470 VAL B 556 CG1 CG2
REMARK 470 TYR B 557 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 CYS B 559 SG
REMARK 470 ILE B 560 CG1 CG2 CD1
REMARK 470 ARG B 562 CG CD NE CZ NH1 NH2
REMARK 470 TRP B 563 CG CD1 CD2 NE1 CE2 CE3 CZ2
REMARK 470 TRP B 563 CZ3 CH2
REMARK 470 LEU B 564 CG CD1 CD2
REMARK 470 THR B 565 OG1 CG2
REMARK 470 LYS B 566 CG CD CE NZ
REMARK 470 ILE B 567 CG1 CG2 CD1
REMARK 470 GLU B 568 CG CD OE1 OE2
REMARK 470 VAL B 569 CG1 CG2
REMARK 470 PRO B 570 CG CD
REMARK 470 LYS B 571 CG CD CE NZ
REMARK 470 THR B 572 OG1 CG2
REMARK 470 GLU B 573 CG CD OE1 OE2
REMARK 470 LYS B 574 CG CD CE NZ
REMARK 470 SER B 575 OG
REMARK 470 PHE B 576 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 GLU B 577 CG CD OE1 OE2
REMARK 470 GLU B 578 CG CD OE1 OE2
REMARK 470 ARG B 579 CG CD NE CZ NH1 NH2
REMARK 470 LEU B 580 CG CD1 CD2
REMARK 470 THR B 581 OG1 CG2
REMARK 470 PHE B 582 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 LYS B 583 CG CD CE NZ
REMARK 470 PHE B 585 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 LEU B 586 CG CD1 CD2
REMARK 470 LEU B 587 CG CD1 CD2
REMARK 470 LYS B 588 CG CD CE NZ
REMARK 470 PHE B 589 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 VAL B 590 CG1 CG2
REMARK 470 ASN B 591 CG OD1 ND2
REMARK 470 SER B 592 OG
REMARK 470 TYR B 593 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 THR B 594 OG1 CG2
REMARK 470 PRO B 595 CG CD
REMARK 470 ILE B 596 CG1 CG2 CD1
REMARK 470 PHE B 597 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 TYR B 598 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 VAL B 599 CG1 CG2
REMARK 470 PHE B 601 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 PHE B 602 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 GLU B 633 CG CD OE1 OE2
REMARK 470 LEU B 634 CG CD1 CD2
REMARK 470 CYS B 635 SG
REMARK 470 ILE B 636 CG1 CG2 CD1
REMARK 470 GLN B 637 CG CD OE1 NE2
REMARK 470 LEU B 638 CG CD1 CD2
REMARK 470 SER B 639 OG
REMARK 470 ILE B 640 CG1 CG2 CD1
REMARK 470 ILE B 641 CG1 CG2 CD1
REMARK 470 MET B 642 CG SD CE
REMARK 470 LEU B 643 CG CD1 CD2
REMARK 470 LYS B 645 CG CD CE NZ
REMARK 470 GLN B 646 CG CD OE1 NE2
REMARK 470 LEU B 647 CG CD1 CD2
REMARK 470 ILE B 648 CG1 CG2 CD1
REMARK 470 GLN B 649 CG CD OE1 NE2
REMARK 470 ASN B 650 CG OD1 ND2
REMARK 470 ASN B 651 CG OD1 ND2
REMARK 470 LEU B 652 CG CD1 CD2
REMARK 470 PHE B 653 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 GLU B 654 CG CD OE1 OE2
REMARK 470 ILE B 655 CG1 CG2 CD1
REMARK 470 ILE B 657 CG1 CG2 CD1
REMARK 470 PRO B 658 CG CD
REMARK 470 LYS B 659 CG CD CE NZ
REMARK 470 MET B 660 CG SD CE
REMARK 470 LYS B 661 CG CD CE NZ
REMARK 470 LYS B 662 CG CD CE NZ
REMARK 470 PHE B 663 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 ILE B 664 CG1 CG2 CD1
REMARK 470 ARG B 665 CG CD NE CZ NH1 NH2
REMARK 470 TYR B 666 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 VAL B 681 CG1 CG2
REMARK 470 LYS B 682 CG CD CE NZ
REMARK 470 ARG B 683 CG CD NE CZ NH1 NH2
REMARK 470 LYS B 684 CG CD CE NZ
REMARK 470 GLN B 685 CG CD OE1 NE2
REMARK 470 ARG B 686 CG CD NE CZ NH1 NH2
REMARK 470 TYR B 687 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 GLU B 688 CG CD OE1 OE2
REMARK 470 VAL B 689 CG1 CG2
REMARK 470 ASP B 690 CG OD1 OD2
REMARK 470 PHE B 691 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 ASN B 692 CG OD1 ND2
REMARK 470 LEU B 699 CG CD1 CD2
REMARK 470 THR B 700 OG1 CG2
REMARK 470 PRO B 701 CG CD
REMARK 470 GLU B 702 CG CD OE1 OE2
REMARK 470 TYR B 703 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 MET B 704 CG SD CE
REMARK 470 GLU B 705 CG CD OE1 OE2
REMARK 470 MET B 706 CG SD CE
REMARK 470 ILE B 707 CG1 CG2 CD1
REMARK 470 ILE B 708 CG1 CG2 CD1
REMARK 470 GLN B 709 CG CD OE1 NE2
REMARK 470 PHE B 710 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 PHE B 712 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 VAL B 713 CG1 CG2
REMARK 470 THR B 714 OG1 CG2
REMARK 470 LEU B 715 CG CD1 CD2
REMARK 470 PHE B 716 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 VAL B 717 CG1 CG2
REMARK 470 SER B 719 OG
REMARK 470 PHE B 720 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 PRO B 721 CG CD
REMARK 470 LEU B 722 CG CD1 CD2
REMARK 470 PRO B 724 CG CD
REMARK 470 LEU B 725 CG CD1 CD2
REMARK 470 PHE B 726 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 LEU B 728 CG CD1 CD2
REMARK 470 LEU B 729 CG CD1 CD2
REMARK 470 ASN B 730 CG OD1 ND2
REMARK 470 ASN B 731 CG OD1 ND2
REMARK 470 ILE B 732 CG1 CG2 CD1
REMARK 470 ILE B 733 CG1 CG2 CD1
REMARK 470 GLU B 734 CG CD OE1 OE2
REMARK 470 ILE B 735 CG1 CG2 CD1
REMARK 470 ARG B 736 CG CD NE CZ NH1 NH2
REMARK 470 LEU B 737 CG CD1 CD2
REMARK 470 ASP B 738 CG OD1 OD2
REMARK 470 LYS B 740 CG CD CE NZ
REMARK 470 LYS B 741 CG CD CE NZ
REMARK 470 PHE B 742 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 VAL B 743 CG1 CG2
REMARK 470 THR B 744 OG1 CG2
REMARK 470 GLU B 745 CG CD OE1 OE2
REMARK 470 LEU B 746 CG CD1 CD2
REMARK 470 ARG B 747 CG CD NE CZ NH1 NH2
REMARK 470 ARG B 748 CG CD NE CZ NH1 NH2
REMARK 470 PRO B 749 CG CD
REMARK 470 VAL B 750 CG1 CG2
REMARK 470 ILE B 752 CG1 CG2 CD1
REMARK 470 ARG B 753 CG CD NE CZ NH1 NH2
REMARK 470 LYS B 755 CG CD CE NZ
REMARK 470 ASP B 756 CG OD1 OD2
REMARK 470 ILE B 757 CG1 CG2 CD1
REMARK 470 ILE B 759 CG1 CG2 CD1
REMARK 470 TRP B 760 CG CD1 CD2 NE1 CE2 CE3 CZ2
REMARK 470 TRP B 760 CZ3 CH2
REMARK 470 TYR B 761 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 ASN B 762 CG OD1 ND2
REMARK 470 ILE B 763 CG1 CG2 CD1
REMARK 470 LEU B 764 CG CD1 CD2
REMARK 470 ARG B 765 CG CD NE CZ NH1 NH2
REMARK 470 VAL B 767 CG1 CG2
REMARK 470 LYS B 769 CG CD CE NZ
REMARK 470 LEU B 770 CG CD1 CD2
REMARK 470 VAL B 772 CG1 CG2
REMARK 470 ILE B 773 CG1 CG2 CD1
REMARK 470 ILE B 774 CG1 CG2 CD1
REMARK 470 ASN B 775 CG OD1 ND2
REMARK 470 PHE B 777 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 VAL B 778 CG1 CG2
REMARK 470 ILE B 779 CG1 CG2 CD1
REMARK 470 SER B 780 OG
REMARK 470 PHE B 781 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 LYS B 855 CG CD CE NZ
REMARK 470 ASP B 856 CG OD1 OD2
REMARK 470 PHE B 857 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 TRP B 858 CG CD1 CD2 NE1 CE2 CE3 CZ2
REMARK 470 TRP B 858 CZ3 CH2
REMARK 470 VAL B 860 CG1 CG2
REMARK 470 LEU B 861 CG CD1 CD2
REMARK 470 ARG B 864 CG CD NE CZ NH1 NH2
REMARK 470 LEU B 865 CG CD1 CD2
REMARK 470 PHE B 867 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 VAL B 868 CG1 CG2
REMARK 470 ILE B 869 CG1 CG2 CD1
REMARK 470 VAL B 870 CG1 CG2
REMARK 470 PHE B 871 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 GLN B 872 CG CD OE1 NE2
REMARK 470 ASN B 873 CG OD1 ND2
REMARK 470 LEU B 874 CG CD1 CD2
REMARK 470 VAL B 875 CG1 CG2
REMARK 470 MET B 876 CG SD CE
REMARK 470 PHE B 877 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 MET B 878 CG SD CE
REMARK 470 SER B 879 OG
REMARK 470 ASP B 880 CG OD1 OD2
REMARK 470 PHE B 881 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 VAL B 882 CG1 CG2
REMARK 470 ASP B 883 CG OD1 OD2
REMARK 470 TRP B 884 CG CD1 CD2 NE1 CE2 CE3 CZ2
REMARK 470 TRP B 884 CZ3 CH2
REMARK 470 VAL B 885 CG1 CG2
REMARK 470 ASP B 892 CG OD1 OD2
REMARK 470 ILE B 893 CG1 CG2 CD1
REMARK 470 SER B 894 OG
REMARK 470 GLN B 895 CG CD OE1 NE2
REMARK 470 GLN B 896 CG CD OE1 NE2
REMARK 470 ILE B 897 CG1 CG2 CD1
REMARK 470 HIS B 898 CG ND1 CD2 CE1 NE2
REMARK 470 LYS B 899 CG CD CE NZ
REMARK 470 GLU B 900 CG CD OE1 OE2
REMARK 470 LYS B 901 CG CD CE NZ
REMARK 470 VAL B 902 CG1 CG2
REMARK 470 LEU B 903 CG CD1 CD2
REMARK 470 MET B 904 CG SD CE
REMARK 470 VAL B 905 CG1 CG2
REMARK 470 GLU B 906 CG CD OE1 OE2
REMARK 470 LEU B 907 CG CD1 CD2
REMARK 470 PHE B 908 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 MET B 909 CG SD CE
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES
REMARK 500
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)
REMARK 500
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996
REMARK 500
REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3
REMARK 500 PRO A 282 C - N - CA ANGL. DEV. = 9.6 DEGREES
REMARK 500 PRO B 282 C - N - CA ANGL. DEV. = 9.6 DEGREES
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: TORSION ANGLES
REMARK 500
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)
REMARK 500
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400
REMARK 500
REMARK 500 M RES CSSEQI PSI PHI
REMARK 500 TYR A 182 -73.11 -66.02
REMARK 500 HIS A 183 28.10 -147.32
REMARK 500 PRO A 316 20.55 -78.16
REMARK 500 LYS A 574 -37.87 -131.29
REMARK 500 THR A 714 -61.53 -90.74
REMARK 500 ASP A 756 -162.22 -161.43
REMARK 500 TYR B 182 -73.10 -66.01
REMARK 500 HIS B 183 28.09 -147.31
REMARK 500 PRO B 316 20.49 -78.14
REMARK 500 LYS B 574 -37.85 -131.27
REMARK 500 THR B 714 -61.56 -90.66
REMARK 500 ASP B 756 -162.21 -161.44
REMARK 500
REMARK 500 REMARK: NULL
REMARK 900
REMARK 900 RELATED ENTRIES
REMARK 900 RELATED ID: EMD-3658 RELATED DB: EMDB
REMARK 900 CRYO-EM STRUCTURE OF THE MTMEM16A ION CHANNEL AT 6.6 A RESOLUTION.
DBREF 5NL2 A 1 960 UNP Q8BHY3 ANO1_MOUSE 1 960
DBREF 5NL2 B 1 960 UNP Q8BHY3 ANO1_MOUSE 1 960
SEQRES 1 A 960 MET ARG VAL PRO GLU LYS TYR SER THR LEU PRO ALA GLU
SEQRES 2 A 960 ASP ARG SER VAL HIS ILE VAL ASN ILE CYS ALA ILE GLU
SEQRES 3 A 960 ASP LEU GLY TYR LEU PRO SER GLU GLY THR LEU LEU ASN
SEQRES 4 A 960 SER LEU SER VAL ASP PRO ASP ALA GLU CYS LYS TYR GLY
SEQRES 5 A 960 LEU TYR PHE ARG ASP GLY LYS ARG LYS VAL ASP TYR ILE
SEQRES 6 A 960 LEU VAL TYR HIS HIS LYS ARG ALA SER GLY SER ARG THR
SEQRES 7 A 960 LEU ALA ARG ARG GLY LEU GLN ASN ASP MET VAL LEU GLY
SEQRES 8 A 960 THR ARG SER VAL ARG GLN ASP GLN PRO LEU PRO GLY LYS
SEQRES 9 A 960 GLY SER PRO VAL ASP ALA GLY SER PRO GLU VAL PRO MET
SEQRES 10 A 960 ASP TYR HIS GLU ASP ASP LYS ARG PHE ARG ARG GLU GLU
SEQRES 11 A 960 TYR GLU GLY ASN LEU LEU GLU ALA GLY LEU GLU LEU GLU
SEQRES 12 A 960 ASN ASP GLU ASP THR LYS ILE HIS GLY VAL GLY PHE VAL
SEQRES 13 A 960 LYS ILE HIS ALA PRO TRP HIS VAL LEU CYS ARG GLU ALA
SEQRES 14 A 960 GLU PHE LEU LYS LEU LYS MET PRO THR LYS LYS VAL TYR
SEQRES 15 A 960 HIS ILE SER GLU THR ARG GLY LEU LEU LYS THR ILE ASN
SEQRES 16 A 960 SER VAL LEU GLN LYS ILE THR ASP PRO ILE GLN PRO LYS
SEQRES 17 A 960 VAL ALA GLU HIS ARG PRO GLN THR THR LYS ARG LEU SER
SEQRES 18 A 960 TYR PRO PHE SER ARG GLU LYS GLN HIS LEU PHE ASP LEU
SEQRES 19 A 960 THR ASP ARG ASP SER PHE PHE ASP SER LYS THR ARG SER
SEQRES 20 A 960 THR ILE VAL TYR GLU ILE LEU LYS ARG THR THR CYS THR
SEQRES 21 A 960 LYS ALA LYS TYR SER MET GLY ILE THR SER LEU LEU ALA
SEQRES 22 A 960 ASN GLY VAL TYR SER ALA ALA TYR PRO LEU HIS ASP GLY
SEQRES 23 A 960 ASP TYR GLU GLY ASP ASN VAL GLU PHE ASN ASP ARG LYS
SEQRES 24 A 960 LEU LEU TYR GLU GLU TRP ALA SER TYR GLY VAL PHE TYR
SEQRES 25 A 960 LYS TYR GLN PRO ILE ASP LEU VAL ARG LYS TYR PHE GLY
SEQRES 26 A 960 GLU LYS VAL GLY LEU TYR PHE ALA TRP LEU GLY ALA TYR
SEQRES 27 A 960 THR GLN MET LEU ILE PRO ALA SER ILE VAL GLY VAL ILE
SEQRES 28 A 960 VAL PHE LEU TYR GLY CYS ALA THR VAL ASP GLU ASN ILE
SEQRES 29 A 960 PRO SER MET GLU MET CYS ASP GLN ARG TYR ASN ILE THR
SEQRES 30 A 960 MET CYS PRO LEU CYS ASP LYS THR CYS SER TYR TRP LYS
SEQRES 31 A 960 MET SER SER ALA CYS ALA THR ALA ARG ALA SER HIS LEU
SEQRES 32 A 960 PHE ASP ASN PRO ALA THR VAL PHE PHE SER VAL PHE MET
SEQRES 33 A 960 ALA LEU TRP ALA ALA THR PHE MET GLU HIS TRP LYS ARG
SEQRES 34 A 960 LYS GLN MET ARG LEU ASN TYR ARG TRP ASP LEU THR GLY
SEQRES 35 A 960 PHE GLU GLU GLU GLU GLU ALA VAL LYS ASP HIS PRO ARG
SEQRES 36 A 960 ALA GLU TYR GLU ALA ARG VAL LEU GLU LYS SER LEU ARG
SEQRES 37 A 960 LYS GLU SER ARG ASN LYS GLU THR ASP LYS VAL LYS LEU
SEQRES 38 A 960 THR TRP ARG ASP ARG PHE PRO ALA TYR PHE THR ASN LEU
SEQRES 39 A 960 VAL SER ILE ILE PHE MET ILE ALA VAL THR PHE ALA ILE
SEQRES 40 A 960 VAL LEU GLY VAL ILE ILE TYR ARG ILE SER THR ALA ALA
SEQRES 41 A 960 ALA LEU ALA MET ASN SER SER PRO SER VAL ARG SER ASN
SEQRES 42 A 960 ILE ARG VAL THR VAL THR ALA THR ALA VAL ILE ILE ASN
SEQRES 43 A 960 LEU VAL VAL ILE ILE LEU LEU ASP GLU VAL TYR GLY CYS
SEQRES 44 A 960 ILE ALA ARG TRP LEU THR LYS ILE GLU VAL PRO LYS THR
SEQRES 45 A 960 GLU LYS SER PHE GLU GLU ARG LEU THR PHE LYS ALA PHE
SEQRES 46 A 960 LEU LEU LYS PHE VAL ASN SER TYR THR PRO ILE PHE TYR
SEQRES 47 A 960 VAL ALA PHE PHE LYS GLY ARG PHE VAL GLY ARG PRO GLY
SEQRES 48 A 960 ASP TYR VAL TYR ILE PHE ARG SER PHE ARG MET GLU GLU
SEQRES 49 A 960 CYS ALA PRO GLY GLY CYS LEU MET GLU LEU CYS ILE GLN
SEQRES 50 A 960 LEU SER ILE ILE MET LEU GLY LYS GLN LEU ILE GLN ASN
SEQRES 51 A 960 ASN LEU PHE GLU ILE GLY ILE PRO LYS MET LYS LYS PHE
SEQRES 52 A 960 ILE ARG TYR LEU LYS LEU ARG ARG GLN SER PRO SER ASP
SEQRES 53 A 960 ARG GLU GLU TYR VAL LYS ARG LYS GLN ARG TYR GLU VAL
SEQRES 54 A 960 ASP PHE ASN LEU GLU PRO PHE ALA GLY LEU THR PRO GLU
SEQRES 55 A 960 TYR MET GLU MET ILE ILE GLN PHE GLY PHE VAL THR LEU
SEQRES 56 A 960 PHE VAL ALA SER PHE PRO LEU ALA PRO LEU PHE ALA LEU
SEQRES 57 A 960 LEU ASN ASN ILE ILE GLU ILE ARG LEU ASP ALA LYS LYS
SEQRES 58 A 960 PHE VAL THR GLU LEU ARG ARG PRO VAL ALA ILE ARG ALA
SEQRES 59 A 960 LYS ASP ILE GLY ILE TRP TYR ASN ILE LEU ARG GLY VAL
SEQRES 60 A 960 GLY LYS LEU ALA VAL ILE ILE ASN ALA PHE VAL ILE SER
SEQRES 61 A 960 PHE THR SER ASP PHE ILE PRO ARG LEU VAL TYR LEU TYR
SEQRES 62 A 960 MET TYR SER GLN ASN GLY THR MET HIS GLY PHE VAL ASN
SEQRES 63 A 960 HIS THR LEU SER SER PHE ASN VAL SER ASP PHE GLN ASN
SEQRES 64 A 960 GLY THR ALA PRO ASN ASP PRO LEU ASP LEU GLY TYR GLU
SEQRES 65 A 960 VAL GLN ILE CYS ARG TYR LYS ASP TYR ARG GLU PRO PRO
SEQRES 66 A 960 TRP SER GLU HIS LYS TYR ASP ILE SER LYS ASP PHE TRP
SEQRES 67 A 960 ALA VAL LEU ALA ALA ARG LEU ALA PHE VAL ILE VAL PHE
SEQRES 68 A 960 GLN ASN LEU VAL MET PHE MET SER ASP PHE VAL ASP TRP
SEQRES 69 A 960 VAL ILE PRO ASP ILE PRO LYS ASP ILE SER GLN GLN ILE
SEQRES 70 A 960 HIS LYS GLU LYS VAL LEU MET VAL GLU LEU PHE MET ARG
SEQRES 71 A 960 GLU GLU GLN GLY LYS GLN GLN LEU LEU ASP THR TRP MET
SEQRES 72 A 960 GLU LYS GLU LYS PRO ARG ASP VAL PRO CYS ASN ASN HIS
SEQRES 73 A 960 SER PRO THR THR HIS PRO GLU ALA GLY ASP GLY SER PRO
SEQRES 74 A 960 VAL PRO SER TYR GLU TYR HIS GLY ASP ALA LEU
SEQRES 1 B 960 MET ARG VAL PRO GLU LYS TYR SER THR LEU PRO ALA GLU
SEQRES 2 B 960 ASP ARG SER VAL HIS ILE VAL ASN ILE CYS ALA ILE GLU
SEQRES 3 B 960 ASP LEU GLY TYR LEU PRO SER GLU GLY THR LEU LEU ASN
SEQRES 4 B 960 SER LEU SER VAL ASP PRO ASP ALA GLU CYS LYS TYR GLY
SEQRES 5 B 960 LEU TYR PHE ARG ASP GLY LYS ARG LYS VAL ASP TYR ILE
SEQRES 6 B 960 LEU VAL TYR HIS HIS LYS ARG ALA SER GLY SER ARG THR
SEQRES 7 B 960 LEU ALA ARG ARG GLY LEU GLN ASN ASP MET VAL LEU GLY
SEQRES 8 B 960 THR ARG SER VAL ARG GLN ASP GLN PRO LEU PRO GLY LYS
SEQRES 9 B 960 GLY SER PRO VAL ASP ALA GLY SER PRO GLU VAL PRO MET
SEQRES 10 B 960 ASP TYR HIS GLU ASP ASP LYS ARG PHE ARG ARG GLU GLU
SEQRES 11 B 960 TYR GLU GLY ASN LEU LEU GLU ALA GLY LEU GLU LEU GLU
SEQRES 12 B 960 ASN ASP GLU ASP THR LYS ILE HIS GLY VAL GLY PHE VAL
SEQRES 13 B 960 LYS ILE HIS ALA PRO TRP HIS VAL LEU CYS ARG GLU ALA
SEQRES 14 B 960 GLU PHE LEU LYS LEU LYS MET PRO THR LYS LYS VAL TYR
SEQRES 15 B 960 HIS ILE SER GLU THR ARG GLY LEU LEU LYS THR ILE ASN
SEQRES 16 B 960 SER VAL LEU GLN LYS ILE THR ASP PRO ILE GLN PRO LYS
SEQRES 17 B 960 VAL ALA GLU HIS ARG PRO GLN THR THR LYS ARG LEU SER
SEQRES 18 B 960 TYR PRO PHE SER ARG GLU LYS GLN HIS LEU PHE ASP LEU
SEQRES 19 B 960 THR ASP ARG ASP SER PHE PHE ASP SER LYS THR ARG SER
SEQRES 20 B 960 THR ILE VAL TYR GLU ILE LEU LYS ARG THR THR CYS THR
SEQRES 21 B 960 LYS ALA LYS TYR SER MET GLY ILE THR SER LEU LEU ALA
SEQRES 22 B 960 ASN GLY VAL TYR SER ALA ALA TYR PRO LEU HIS ASP GLY
SEQRES 23 B 960 ASP TYR GLU GLY ASP ASN VAL GLU PHE ASN ASP ARG LYS
SEQRES 24 B 960 LEU LEU TYR GLU GLU TRP ALA SER TYR GLY VAL PHE TYR
SEQRES 25 B 960 LYS TYR GLN PRO ILE ASP LEU VAL ARG LYS TYR PHE GLY
SEQRES 26 B 960 GLU LYS VAL GLY LEU TYR PHE ALA TRP LEU GLY ALA TYR
SEQRES 27 B 960 THR GLN MET LEU ILE PRO ALA SER ILE VAL GLY VAL ILE
SEQRES 28 B 960 VAL PHE LEU TYR GLY CYS ALA THR VAL ASP GLU ASN ILE
SEQRES 29 B 960 PRO SER MET GLU MET CYS ASP GLN ARG TYR ASN ILE THR
SEQRES 30 B 960 MET CYS PRO LEU CYS ASP LYS THR CYS SER TYR TRP LYS
SEQRES 31 B 960 MET SER SER ALA CYS ALA THR ALA ARG ALA SER HIS LEU
SEQRES 32 B 960 PHE ASP ASN PRO ALA THR VAL PHE PHE SER VAL PHE MET
SEQRES 33 B 960 ALA LEU TRP ALA ALA THR PHE MET GLU HIS TRP LYS ARG
SEQRES 34 B 960 LYS GLN MET ARG LEU ASN TYR ARG TRP ASP LEU THR GLY
SEQRES 35 B 960 PHE GLU GLU GLU GLU GLU ALA VAL LYS ASP HIS PRO ARG
SEQRES 36 B 960 ALA GLU TYR GLU ALA ARG VAL LEU GLU LYS SER LEU ARG
SEQRES 37 B 960 LYS GLU SER ARG ASN LYS GLU THR ASP LYS VAL LYS LEU
SEQRES 38 B 960 THR TRP ARG ASP ARG PHE PRO ALA TYR PHE THR ASN LEU
SEQRES 39 B 960 VAL SER ILE ILE PHE MET ILE ALA VAL THR PHE ALA ILE
SEQRES 40 B 960 VAL LEU GLY VAL ILE ILE TYR ARG ILE SER THR ALA ALA
SEQRES 41 B 960 ALA LEU ALA MET ASN SER SER PRO SER VAL ARG SER ASN
SEQRES 42 B 960 ILE ARG VAL THR VAL THR ALA THR ALA VAL ILE ILE ASN
SEQRES 43 B 960 LEU VAL VAL ILE ILE LEU LEU ASP GLU VAL TYR GLY CYS
SEQRES 44 B 960 ILE ALA ARG TRP LEU THR LYS ILE GLU VAL PRO LYS THR
SEQRES 45 B 960 GLU LYS SER PHE GLU GLU ARG LEU THR PHE LYS ALA PHE
SEQRES 46 B 960 LEU LEU LYS PHE VAL ASN SER TYR THR PRO ILE PHE TYR
SEQRES 47 B 960 VAL ALA PHE PHE LYS GLY ARG PHE VAL GLY ARG PRO GLY
SEQRES 48 B 960 ASP TYR VAL TYR ILE PHE ARG SER PHE ARG MET GLU GLU
SEQRES 49 B 960 CYS ALA PRO GLY GLY CYS LEU MET GLU LEU CYS ILE GLN
SEQRES 50 B 960 LEU SER ILE ILE MET LEU GLY LYS GLN LEU ILE GLN ASN
SEQRES 51 B 960 ASN LEU PHE GLU ILE GLY ILE PRO LYS MET LYS LYS PHE
SEQRES 52 B 960 ILE ARG TYR LEU LYS LEU ARG ARG GLN SER PRO SER ASP
SEQRES 53 B 960 ARG GLU GLU TYR VAL LYS ARG LYS GLN ARG TYR GLU VAL
SEQRES 54 B 960 ASP PHE ASN LEU GLU PRO PHE ALA GLY LEU THR PRO GLU
SEQRES 55 B 960 TYR MET GLU MET ILE ILE GLN PHE GLY PHE VAL THR LEU
SEQRES 56 B 960 PHE VAL ALA SER PHE PRO LEU ALA PRO LEU PHE ALA LEU
SEQRES 57 B 960 LEU ASN ASN ILE ILE GLU ILE ARG LEU ASP ALA LYS LYS
SEQRES 58 B 960 PHE VAL THR GLU LEU ARG ARG PRO VAL ALA ILE ARG ALA
SEQRES 59 B 960 LYS ASP ILE GLY ILE TRP TYR ASN ILE LEU ARG GLY VAL
SEQRES 60 B 960 GLY LYS LEU ALA VAL ILE ILE ASN ALA PHE VAL ILE SER
SEQRES 61 B 960 PHE THR SER ASP PHE ILE PRO ARG LEU VAL TYR LEU TYR
SEQRES 62 B 960 MET TYR SER GLN ASN GLY THR MET HIS GLY PHE VAL ASN
SEQRES 63 B 960 HIS THR LEU SER SER PHE ASN VAL SER ASP PHE GLN ASN
SEQRES 64 B 960 GLY THR ALA PRO ASN ASP PRO LEU ASP LEU GLY TYR GLU
SEQRES 65 B 960 VAL GLN ILE CYS ARG TYR LYS ASP TYR ARG GLU PRO PRO
SEQRES 66 B 960 TRP SER GLU HIS LYS TYR ASP ILE SER LYS ASP PHE TRP
SEQRES 67 B 960 ALA VAL LEU ALA ALA ARG LEU ALA PHE VAL ILE VAL PHE
SEQRES 68 B 960 GLN ASN LEU VAL MET PHE MET SER ASP PHE VAL ASP TRP
SEQRES 69 B 960 VAL ILE PRO ASP ILE PRO LYS ASP ILE SER GLN GLN ILE
SEQRES 70 B 960 HIS LYS GLU LYS VAL LEU MET VAL GLU LEU PHE MET ARG
SEQRES 71 B 960 GLU GLU GLN GLY LYS GLN GLN LEU LEU ASP THR TRP MET
SEQRES 72 B 960 GLU LYS GLU LYS PRO ARG ASP VAL PRO CYS ASN ASN HIS
SEQRES 73 B 960 SER PRO THR THR HIS PRO GLU ALA GLY ASP GLY SER PRO
SEQRES 74 B 960 VAL PRO SER TYR GLU TYR HIS GLY ASP ALA LEU
HELIX 1 AA1 GLU A 168 ILE A 184 1 17
HELIX 2 AA2 ILE A 205 ARG A 213 1 9
HELIX 3 AA3 SER A 243 LEU A 254 1 12
HELIX 4 AA4 ASN A 296 TRP A 305 1 10
HELIX 5 AA5 PRO A 316 PHE A 324 1 9
HELIX 6 AA6 GLU A 326 TYR A 355 1 30
HELIX 7 AA7 VAL A 410 ARG A 437 1 28
HELIX 8 AA8 PHE A 487 THR A 518 1 32
HELIX 9 AA9 VAL A 536 ILE A 567 1 32
HELIX 10 AB1 SER A 575 PHE A 601 1 27
HELIX 11 AB2 LEU A 634 LEU A 647 1 14
HELIX 12 AB3 GLN A 649 TYR A 666 1 18
HELIX 13 AB4 LYS A 682 ASN A 692 1 11
HELIX 14 AB5 LEU A 699 LEU A 715 1 17
HELIX 15 AB6 PHE A 716 ALA A 718 5 3
HELIX 16 AB7 LEU A 722 THR A 744 1 23
HELIX 17 AB8 GLY A 758 PHE A 781 1 24
HELIX 18 AB9 ASP A 856 TRP A 884 1 29
HELIX 19 AC1 ILE A 893 MET A 909 1 17
HELIX 20 AC2 GLU B 168 ILE B 184 1 17
HELIX 21 AC3 ILE B 205 ARG B 213 1 9
HELIX 22 AC4 SER B 243 LEU B 254 1 12
HELIX 23 AC5 ASN B 296 TRP B 305 1 10
HELIX 24 AC6 PRO B 316 PHE B 324 1 9
HELIX 25 AC7 GLU B 326 TYR B 355 1 30
HELIX 26 AC8 VAL B 410 ARG B 437 1 28
HELIX 27 AC9 PHE B 487 THR B 518 1 32
HELIX 28 AD1 VAL B 536 ILE B 567 1 32
HELIX 29 AD2 SER B 575 PHE B 601 1 27
HELIX 30 AD3 LEU B 634 LEU B 647 1 14
HELIX 31 AD4 GLN B 649 TYR B 666 1 18
HELIX 32 AD5 LYS B 682 ASN B 692 1 11
HELIX 33 AD6 LEU B 699 LEU B 715 1 17
HELIX 34 AD7 PHE B 716 ALA B 718 5 3
HELIX 35 AD8 LEU B 722 THR B 744 1 23
HELIX 36 AD9 GLY B 758 PHE B 781 1 24
HELIX 37 AE1 ASP B 856 TRP B 884 1 29
HELIX 38 AE2 ILE B 893 MET B 909 1 17
SHEET 1 AA1 2 LYS A 124 PHE A 126 0
SHEET 2 AA1 2 ALA A 279 TYR A 281 -1 O ALA A 279 N PHE A 126
SHEET 1 AA2 2 GLU A 186 LEU A 191 0
SHEET 2 AA2 2 ILE A 194 GLN A 199 -1 O SER A 196 N GLY A 189
SHEET 1 AA3 2 LYS B 124 PHE B 126 0
SHEET 2 AA3 2 ALA B 279 TYR B 281 -1 O ALA B 279 N PHE B 126
SHEET 1 AA4 2 GLU B 186 LEU B 191 0
SHEET 2 AA4 2 ILE B 194 GLN B 199 -1 O SER B 196 N GLY B 189
CRYST1 1.000 1.000 1.000 90.00 90.00 90.00 P 1 1
ORIGX1 1.000000 0.000000 0.000000 0.00000
ORIGX2 0.000000 1.000000 0.000000 0.00000
ORIGX3 0.000000 0.000000 1.000000 0.00000
SCALE1 1.000000 0.000000 0.000000 0.00000
SCALE2 0.000000 1.000000 0.000000 0.00000
SCALE3 0.000000 0.000000 1.000000 0.00000
(ATOM LINES ARE NOT SHOWN.)
END
