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Database: PDB
Entry: 5VFT
LinkDB: 5VFT
Original site: 5VFT 
HEADER    HYDROLASE                               09-APR-17   5VFT              
TITLE     NUCLEOTIDE-DRIVEN TRIPLE-STATE REMODELING OF THE AAA-ATPASE CHANNEL IN
TITLE    2 THE ACTIVATED HUMAN 26S PROTEASOME                                   
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 1;            
COMPND   3 CHAIN: U;                                                            
COMPND   4 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN2,26S PROTEASOME       
COMPND   5 REGULATORY SUBUNIT S1,26S PROTEASOME SUBUNIT P112;                   
COMPND   6 ENGINEERED: YES;                                                     
COMPND   7 MOL_ID: 2;                                                           
COMPND   8 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3;            
COMPND   9 CHAIN: V;                                                            
COMPND  10 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN3,26S PROTEASOME       
COMPND  11 REGULATORY SUBUNIT S3,PROTEASOME SUBUNIT P58;                        
COMPND  12 ENGINEERED: YES;                                                     
COMPND  13 MOL_ID: 3;                                                           
COMPND  14 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12;           
COMPND  15 CHAIN: W;                                                            
COMPND  16 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN5,26S PROTEASOME       
COMPND  17 REGULATORY SUBUNIT P55;                                              
COMPND  18 ENGINEERED: YES;                                                     
COMPND  19 MOL_ID: 4;                                                           
COMPND  20 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11;           
COMPND  21 CHAIN: X;                                                            
COMPND  22 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN6,26S PROTEASOME       
COMPND  23 REGULATORY SUBUNIT S9,26S PROTEASOME REGULATORY SUBUNIT P44.5;       
COMPND  24 ENGINEERED: YES;                                                     
COMPND  25 MOL_ID: 5;                                                           
COMPND  26 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 6;            
COMPND  27 CHAIN: Y;                                                            
COMPND  28 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN7,26S PROTEASOME       
COMPND  29 REGULATORY SUBUNIT S10,BREAST CANCER-ASSOCIATED PROTEIN SGA-113M,    
COMPND  30 PHOSPHONOFORMATE IMMUNO-ASSOCIATED PROTEIN 4,PROTEASOME REGULATORY   
COMPND  31 PARTICLE SUBUNIT P44S10,P42A;                                        
COMPND  32 ENGINEERED: YES;                                                     
COMPND  33 MOL_ID: 6;                                                           
COMPND  34 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 7;            
COMPND  35 CHAIN: Z;                                                            
COMPND  36 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN8,26S PROTEASOME       
COMPND  37 REGULATORY SUBUNIT S12,MOV34 PROTEIN HOMOLOG,PROTEASOME SUBUNIT P40; 
COMPND  38 ENGINEERED: YES;                                                     
COMPND  39 MOL_ID: 7;                                                           
COMPND  40 MOLECULE: PROTEASOME (PROSOME, MACROPAIN) 26S SUBUNIT, NON-ATPASE,   
COMPND  41 13, ISOFORM CRA_A;                                                   
COMPND  42 CHAIN: a;                                                            
COMPND  43 ENGINEERED: YES;                                                     
COMPND  44 MOL_ID: 8;                                                           
COMPND  45 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4;            
COMPND  46 CHAIN: b;                                                            
COMPND  47 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN10,26S PROTEASOME      
COMPND  48 REGULATORY SUBUNIT S5A,ANTISECRETORY FACTOR 1,ASF,MULTIUBIQUITIN     
COMPND  49 CHAIN-BINDING PROTEIN;                                               
COMPND  50 ENGINEERED: YES;                                                     
COMPND  51 MOL_ID: 9;                                                           
COMPND  52 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 14;           
COMPND  53 CHAIN: c;                                                            
COMPND  54 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN11,26S PROTEASOME-     
COMPND  55 ASSOCIATED PAD1 HOMOLOG 1;                                           
COMPND  56 EC: 3.4.19.-;                                                        
COMPND  57 ENGINEERED: YES;                                                     
COMPND  58 MOL_ID: 10;                                                          
COMPND  59 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8;            
COMPND  60 CHAIN: d;                                                            
COMPND  61 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN12,26S PROTEASOME      
COMPND  62 REGULATORY SUBUNIT S14,P31;                                          
COMPND  63 ENGINEERED: YES;                                                     
COMPND  64 MOL_ID: 11;                                                          
COMPND  65 MOLECULE: SEM1;                                                      
COMPND  66 CHAIN: e;                                                            
COMPND  67 ENGINEERED: YES;                                                     
COMPND  68 MOL_ID: 12;                                                          
COMPND  69 MOLECULE: 26S PROTEASOME REGULATORY SUBUNIT 7;                       
COMPND  70 CHAIN: A;                                                            
COMPND  71 SYNONYM: 26S PROTEASOME AAA-ATPASE SUBUNIT RPT1,PROTEASOME 26S       
COMPND  72 SUBUNIT ATPASE 2,PROTEIN MSS1;                                       
COMPND  73 ENGINEERED: YES;                                                     
COMPND  74 MOL_ID: 13;                                                          
COMPND  75 MOLECULE: 26S PROTEASOME REGULATORY SUBUNIT 4;                       
COMPND  76 CHAIN: B;                                                            
COMPND  77 SYNONYM: P26S4,26S PROTEASOME AAA-ATPASE SUBUNIT RPT2,PROTEASOME 26S 
COMPND  78 SUBUNIT ATPASE 1;                                                    
COMPND  79 ENGINEERED: YES;                                                     
COMPND  80 MOL_ID: 14;                                                          
COMPND  81 MOLECULE: 26S PROTEASOME REGULATORY SUBUNIT 8;                       
COMPND  82 CHAIN: C;                                                            
COMPND  83 SYNONYM: 26S PROTEASOME AAA-ATPASE SUBUNIT RPT6,PROTEASOME 26S       
COMPND  84 SUBUNIT ATPASE 5,PROTEASOME SUBUNIT P45,THYROID HORMONE RECEPTOR-    
COMPND  85 INTERACTING PROTEIN 1,TRIP1,P45/SUG;                                 
COMPND  86 ENGINEERED: YES;                                                     
COMPND  87 MOL_ID: 15;                                                          
COMPND  88 MOLECULE: 26S PROTEASOME REGULATORY SUBUNIT 6B;                      
COMPND  89 CHAIN: D;                                                            
COMPND  90 SYNONYM: 26S PROTEASOME AAA-ATPASE SUBUNIT RPT3,MB67-INTERACTING     
COMPND  91 PROTEIN,MIP224,PROTEASOME 26S SUBUNIT ATPASE 4,TAT-BINDING PROTEIN 7,
COMPND  92 TBP-7;                                                               
COMPND  93 ENGINEERED: YES;                                                     
COMPND  94 MOL_ID: 16;                                                          
COMPND  95 MOLECULE: 26S PROTEASOME REGULATORY SUBUNIT 10B;                     
COMPND  96 CHAIN: E;                                                            
COMPND  97 SYNONYM: 26S PROTEASOME AAA-ATPASE SUBUNIT RPT4,PROTEASOME 26S       
COMPND  98 SUBUNIT ATPASE 6,PROTEASOME SUBUNIT P42;                             
COMPND  99 ENGINEERED: YES;                                                     
COMPND 100 MOL_ID: 17;                                                          
COMPND 101 MOLECULE: 26S PROTEASOME REGULATORY SUBUNIT 6A;                      
COMPND 102 CHAIN: F;                                                            
COMPND 103 SYNONYM: 26S PROTEASOME AAA-ATPASE SUBUNIT RPT5,PROTEASOME 26S       
COMPND 104 SUBUNIT ATPASE 3,PROTEASOME SUBUNIT P50,TAT-BINDING PROTEIN 1,TBP-1; 
COMPND 105 ENGINEERED: YES;                                                     
COMPND 106 MOL_ID: 18;                                                          
COMPND 107 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-6;                           
COMPND 108 CHAIN: G, g;                                                         
COMPND 109 SYNONYM: 27 KDA PROSOMAL PROTEIN,P27K,MACROPAIN IOTA CHAIN,          
COMPND 110 MULTICATALYTIC ENDOPEPTIDASE COMPLEX IOTA CHAIN,PROTEASOME IOTA      
COMPND 111 CHAIN;                                                               
COMPND 112 EC: 3.4.25.1;                                                        
COMPND 113 ENGINEERED: YES;                                                     
COMPND 114 MOL_ID: 19;                                                          
COMPND 115 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-2;                           
COMPND 116 CHAIN: H, h;                                                         
COMPND 117 SYNONYM: MACROPAIN SUBUNIT C3,MULTICATALYTIC ENDOPEPTIDASE COMPLEX   
COMPND 118 SUBUNIT C3,PROTEASOME COMPONENT C3;                                  
COMPND 119 EC: 3.4.25.1;                                                        
COMPND 120 ENGINEERED: YES;                                                     
COMPND 121 MOL_ID: 20;                                                          
COMPND 122 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-4;                           
COMPND 123 CHAIN: I, i;                                                         
COMPND 124 SYNONYM: MACROPAIN SUBUNIT C9,MULTICATALYTIC ENDOPEPTIDASE COMPLEX   
COMPND 125 SUBUNIT C9,PROTEASOME COMPONENT C9,PROTEASOME SUBUNIT L;             
COMPND 126 EC: 3.4.25.1;                                                        
COMPND 127 ENGINEERED: YES;                                                     
COMPND 128 MOL_ID: 21;                                                          
COMPND 129 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-7;                           
COMPND 130 CHAIN: J, j;                                                         
COMPND 131 SYNONYM: PROTEASOME SUBUNIT RC6-1,PROTEASOME SUBUNIT XAPC7;          
COMPND 132 EC: 3.4.25.1;                                                        
COMPND 133 ENGINEERED: YES;                                                     
COMPND 134 MOL_ID: 22;                                                          
COMPND 135 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-5;                           
COMPND 136 CHAIN: K, k;                                                         
COMPND 137 SYNONYM: MACROPAIN ZETA CHAIN,MULTICATALYTIC ENDOPEPTIDASE COMPLEX   
COMPND 138 ZETA CHAIN,PROTEASOME ZETA CHAIN;                                    
COMPND 139 EC: 3.4.25.1;                                                        
COMPND 140 ENGINEERED: YES;                                                     
COMPND 141 MOL_ID: 23;                                                          
COMPND 142 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-1;                           
COMPND 143 CHAIN: L, l;                                                         
COMPND 144 SYNONYM: 30 KDA PROSOMAL PROTEIN,PROS-30,MACROPAIN SUBUNIT C2,       
COMPND 145 MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT C2,PROTEASOME COMPONENT 
COMPND 146 C2,PROTEASOME NU CHAIN;                                              
COMPND 147 EC: 3.4.25.1;                                                        
COMPND 148 ENGINEERED: YES;                                                     
COMPND 149 MOL_ID: 24;                                                          
COMPND 150 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-3;                           
COMPND 151 CHAIN: M, m;                                                         
COMPND 152 SYNONYM: MACROPAIN SUBUNIT C8,MULTICATALYTIC ENDOPEPTIDASE COMPLEX   
COMPND 153 SUBUNIT C8,PROTEASOME COMPONENT C8;                                  
COMPND 154 EC: 3.4.25.1;                                                        
COMPND 155 ENGINEERED: YES;                                                     
COMPND 156 MOL_ID: 25;                                                          
COMPND 157 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-6;                            
COMPND 158 CHAIN: N, n;                                                         
COMPND 159 SYNONYM: MACROPAIN DELTA CHAIN,MULTICATALYTIC ENDOPEPTIDASE COMPLEX  
COMPND 160 DELTA CHAIN,PROTEASOME DELTA CHAIN,PROTEASOME SUBUNIT Y;             
COMPND 161 EC: 3.4.25.1;                                                        
COMPND 162 ENGINEERED: YES;                                                     
COMPND 163 MOL_ID: 26;                                                          
COMPND 164 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-7;                            
COMPND 165 CHAIN: O, o;                                                         
COMPND 166 SYNONYM: MACROPAIN CHAIN Z,MULTICATALYTIC ENDOPEPTIDASE COMPLEX CHAIN
COMPND 167 Z,PROTEASOME SUBUNIT Z;                                              
COMPND 168 EC: 3.4.25.1;                                                        
COMPND 169 ENGINEERED: YES;                                                     
COMPND 170 MOL_ID: 27;                                                          
COMPND 171 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-3;                            
COMPND 172 CHAIN: P, p;                                                         
COMPND 173 SYNONYM: PROTEASOME CHAIN 13,PROTEASOME COMPONENT C10-II,PROTEASOME  
COMPND 174 THETA CHAIN;                                                         
COMPND 175 EC: 3.4.25.1;                                                        
COMPND 176 ENGINEERED: YES;                                                     
COMPND 177 MOL_ID: 28;                                                          
COMPND 178 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-2;                            
COMPND 179 CHAIN: Q, q;                                                         
COMPND 180 SYNONYM: MACROPAIN SUBUNIT C7-I,MULTICATALYTIC ENDOPEPTIDASE COMPLEX 
COMPND 181 SUBUNIT C7-I,PROTEASOME COMPONENT C7-I;                              
COMPND 182 EC: 3.4.25.1;                                                        
COMPND 183 ENGINEERED: YES;                                                     
COMPND 184 MOL_ID: 29;                                                          
COMPND 185 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-5;                            
COMPND 186 CHAIN: R, r;                                                         
COMPND 187 SYNONYM: MACROPAIN EPSILON CHAIN,MULTICATALYTIC ENDOPEPTIDASE COMPLEX
COMPND 188 EPSILON CHAIN,PROTEASOME CHAIN 6,PROTEASOME EPSILON CHAIN,PROTEASOME 
COMPND 189 SUBUNIT MB1,PROTEASOME SUBUNIT X;                                    
COMPND 190 EC: 3.4.25.1;                                                        
COMPND 191 ENGINEERED: YES;                                                     
COMPND 192 MOL_ID: 30;                                                          
COMPND 193 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-1;                            
COMPND 194 CHAIN: S, s;                                                         
COMPND 195 SYNONYM: MACROPAIN SUBUNIT C5,MULTICATALYTIC ENDOPEPTIDASE COMPLEX   
COMPND 196 SUBUNIT C5,PROTEASOME COMPONENT C5,PROTEASOME GAMMA CHAIN;           
COMPND 197 EC: 3.4.25.1;                                                        
COMPND 198 ENGINEERED: YES;                                                     
COMPND 199 MOL_ID: 31;                                                          
COMPND 200 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-4;                            
COMPND 201 CHAIN: T, t;                                                         
COMPND 202 SYNONYM: 26 KDA PROSOMAL PROTEIN,PROS-26,MACROPAIN BETA CHAIN,       
COMPND 203 MULTICATALYTIC ENDOPEPTIDASE COMPLEX BETA CHAIN,PROTEASOME BETA      
COMPND 204 CHAIN,PROTEASOME CHAIN 3,HSN3;                                       
COMPND 205 EC: 3.4.25.1;                                                        
COMPND 206 ENGINEERED: YES;                                                     
COMPND 207 MOL_ID: 32;                                                          
COMPND 208 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 2;            
COMPND 209 CHAIN: f;                                                            
COMPND 210 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN1,26S PROTEASOME       
COMPND 211 REGULATORY SUBUNIT S2,26S PROTEASOME SUBUNIT P97,PROTEIN 55.11,TUMOR 
COMPND 212 NECROSIS FACTOR TYPE 1 RECEPTOR-ASSOCIATED PROTEIN 2;                
COMPND 213 ENGINEERED: YES                                                      
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE   3 ORGANISM_COMMON: HUMAN;                                              
SOURCE   4 ORGANISM_TAXID: 9606;                                                
SOURCE   5 GENE: PSMD1;                                                         
SOURCE   6 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE   7 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE   8 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE   9 MOL_ID: 2;                                                           
SOURCE  10 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  11 ORGANISM_COMMON: HUMAN;                                              
SOURCE  12 ORGANISM_TAXID: 9606;                                                
SOURCE  13 GENE: PSMD3;                                                         
SOURCE  14 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE  15 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE  16 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE  17 MOL_ID: 3;                                                           
SOURCE  18 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  19 ORGANISM_COMMON: HUMAN;                                              
SOURCE  20 ORGANISM_TAXID: 9606;                                                
SOURCE  21 GENE: PSMD12;                                                        
SOURCE  22 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE  23 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE  24 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE  25 MOL_ID: 4;                                                           
SOURCE  26 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  27 ORGANISM_COMMON: HUMAN;                                              
SOURCE  28 ORGANISM_TAXID: 9606;                                                
SOURCE  29 GENE: PSMD11;                                                        
SOURCE  30 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE  31 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE  32 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE  33 MOL_ID: 5;                                                           
SOURCE  34 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  35 ORGANISM_COMMON: HUMAN;                                              
SOURCE  36 ORGANISM_TAXID: 9606;                                                
SOURCE  37 GENE: PSMD6, KIAA0107, PFAAP4;                                       
SOURCE  38 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE  39 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE  40 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE  41 MOL_ID: 6;                                                           
SOURCE  42 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  43 ORGANISM_COMMON: HUMAN;                                              
SOURCE  44 ORGANISM_TAXID: 9606;                                                
SOURCE  45 GENE: PSMD7, MOV34L;                                                 
SOURCE  46 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE  47 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE  48 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE  49 MOL_ID: 7;                                                           
SOURCE  50 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  51 ORGANISM_COMMON: HUMAN;                                              
SOURCE  52 ORGANISM_TAXID: 9606;                                                
SOURCE  53 GENE: PSMD13, HCG_37689;                                             
SOURCE  54 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE  55 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE  56 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE  57 MOL_ID: 8;                                                           
SOURCE  58 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  59 ORGANISM_COMMON: HUMAN;                                              
SOURCE  60 ORGANISM_TAXID: 9606;                                                
SOURCE  61 GENE: PSMD4, MCB1;                                                   
SOURCE  62 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE  63 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE  64 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE  65 MOL_ID: 9;                                                           
SOURCE  66 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  67 ORGANISM_COMMON: HUMAN;                                              
SOURCE  68 ORGANISM_TAXID: 9606;                                                
SOURCE  69 GENE: PSMD14, POH1;                                                  
SOURCE  70 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE  71 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE  72 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE  73 MOL_ID: 10;                                                          
SOURCE  74 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  75 ORGANISM_COMMON: HUMAN;                                              
SOURCE  76 ORGANISM_TAXID: 9606;                                                
SOURCE  77 GENE: PSMD8;                                                         
SOURCE  78 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE  79 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE  80 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE  81 MOL_ID: 11;                                                          
SOURCE  82 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  83 ORGANISM_COMMON: HUMAN;                                              
SOURCE  84 ORGANISM_TAXID: 9606;                                                
SOURCE  85 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE  86 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE  87 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE  88 MOL_ID: 12;                                                          
SOURCE  89 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  90 ORGANISM_COMMON: HUMAN;                                              
SOURCE  91 ORGANISM_TAXID: 9606;                                                
SOURCE  92 GENE: PSMC2, MSS1;                                                   
SOURCE  93 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE  94 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE  95 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE  96 MOL_ID: 13;                                                          
SOURCE  97 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  98 ORGANISM_COMMON: HUMAN;                                              
SOURCE  99 ORGANISM_TAXID: 9606;                                                
SOURCE 100 GENE: PSMC1;                                                         
SOURCE 101 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 102 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 103 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 104 MOL_ID: 14;                                                          
SOURCE 105 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 106 ORGANISM_COMMON: HUMAN;                                              
SOURCE 107 ORGANISM_TAXID: 9606;                                                
SOURCE 108 GENE: PSMC5, SUG1;                                                   
SOURCE 109 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 110 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 111 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 112 MOL_ID: 15;                                                          
SOURCE 113 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 114 ORGANISM_COMMON: HUMAN;                                              
SOURCE 115 ORGANISM_TAXID: 9606;                                                
SOURCE 116 GENE: PSMC4, MIP224, TBP7;                                           
SOURCE 117 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 118 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 119 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 120 MOL_ID: 16;                                                          
SOURCE 121 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 122 ORGANISM_COMMON: HUMAN;                                              
SOURCE 123 ORGANISM_TAXID: 9606;                                                
SOURCE 124 GENE: PSMC6, SUG2;                                                   
SOURCE 125 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 126 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 127 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 128 MOL_ID: 17;                                                          
SOURCE 129 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 130 ORGANISM_COMMON: HUMAN;                                              
SOURCE 131 ORGANISM_TAXID: 9606;                                                
SOURCE 132 GENE: PSMC3, TBP1;                                                   
SOURCE 133 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 134 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 135 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 136 MOL_ID: 18;                                                          
SOURCE 137 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 138 ORGANISM_COMMON: HUMAN;                                              
SOURCE 139 ORGANISM_TAXID: 9606;                                                
SOURCE 140 GENE: PSMA6, PROS27;                                                 
SOURCE 141 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 142 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 143 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 144 MOL_ID: 19;                                                          
SOURCE 145 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 146 ORGANISM_COMMON: HUMAN;                                              
SOURCE 147 ORGANISM_TAXID: 9606;                                                
SOURCE 148 GENE: PSMA2, HC3, PSC3;                                              
SOURCE 149 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 150 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 151 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 152 MOL_ID: 20;                                                          
SOURCE 153 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 154 ORGANISM_COMMON: HUMAN;                                              
SOURCE 155 ORGANISM_TAXID: 9606;                                                
SOURCE 156 GENE: PSMA4, HC9, PSC9;                                              
SOURCE 157 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 158 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 159 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 160 MOL_ID: 21;                                                          
SOURCE 161 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 162 ORGANISM_COMMON: HUMAN;                                              
SOURCE 163 ORGANISM_TAXID: 9606;                                                
SOURCE 164 GENE: PSMA7, HSPC;                                                   
SOURCE 165 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 166 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 167 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 168 MOL_ID: 22;                                                          
SOURCE 169 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 170 ORGANISM_COMMON: HUMAN;                                              
SOURCE 171 ORGANISM_TAXID: 9606;                                                
SOURCE 172 GENE: PSMA5;                                                         
SOURCE 173 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 174 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 175 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 176 MOL_ID: 23;                                                          
SOURCE 177 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 178 ORGANISM_COMMON: HUMAN;                                              
SOURCE 179 ORGANISM_TAXID: 9606;                                                
SOURCE 180 GENE: PSMA1, HC2, NU, PROS30, PSC2;                                  
SOURCE 181 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 182 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 183 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 184 MOL_ID: 24;                                                          
SOURCE 185 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 186 ORGANISM_COMMON: HUMAN;                                              
SOURCE 187 ORGANISM_TAXID: 9606;                                                
SOURCE 188 GENE: PSMA3, HC8, PSC8;                                              
SOURCE 189 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 190 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 191 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 192 MOL_ID: 25;                                                          
SOURCE 193 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 194 ORGANISM_COMMON: HUMAN;                                              
SOURCE 195 ORGANISM_TAXID: 9606;                                                
SOURCE 196 GENE: PSMB6, LMPY, Y;                                                
SOURCE 197 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 198 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 199 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 200 MOL_ID: 26;                                                          
SOURCE 201 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 202 ORGANISM_COMMON: HUMAN;                                              
SOURCE 203 ORGANISM_TAXID: 9606;                                                
SOURCE 204 GENE: PSMB7, Z;                                                      
SOURCE 205 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 206 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 207 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 208 MOL_ID: 27;                                                          
SOURCE 209 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 210 ORGANISM_COMMON: HUMAN;                                              
SOURCE 211 ORGANISM_TAXID: 9606;                                                
SOURCE 212 GENE: PSMB3;                                                         
SOURCE 213 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 214 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 215 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 216 MOL_ID: 28;                                                          
SOURCE 217 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 218 ORGANISM_COMMON: HUMAN;                                              
SOURCE 219 ORGANISM_TAXID: 9606;                                                
SOURCE 220 GENE: PSMB2;                                                         
SOURCE 221 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 222 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 223 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 224 MOL_ID: 29;                                                          
SOURCE 225 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 226 ORGANISM_COMMON: HUMAN;                                              
SOURCE 227 ORGANISM_TAXID: 9606;                                                
SOURCE 228 GENE: PSMB5, LMPX, MB1, X;                                           
SOURCE 229 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 230 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 231 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 232 MOL_ID: 30;                                                          
SOURCE 233 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 234 ORGANISM_COMMON: HUMAN;                                              
SOURCE 235 ORGANISM_TAXID: 9606;                                                
SOURCE 236 GENE: PSMB1, PSC5;                                                   
SOURCE 237 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 238 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 239 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 240 MOL_ID: 31;                                                          
SOURCE 241 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 242 ORGANISM_COMMON: HUMAN;                                              
SOURCE 243 ORGANISM_TAXID: 9606;                                                
SOURCE 244 GENE: PSMB4, PROS26;                                                 
SOURCE 245 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 246 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 247 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 248 MOL_ID: 32;                                                          
SOURCE 249 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 250 ORGANISM_COMMON: HUMAN;                                              
SOURCE 251 ORGANISM_TAXID: 9606;                                                
SOURCE 252 GENE: PSMD2, TRAP2;                                                  
SOURCE 253 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 254 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 255 EXPRESSION_SYSTEM_TAXID: 9606                                        
KEYWDS    26S PROTEASOME, ATP-DEPENDENT PROTEASE, AAA-ATPASE, PEPTIDE-UNFOLDING 
KEYWDS   2 CHANNEL, 20S CORE PARTICLE, HYDROLASE                                
EXPDTA    ELECTRON MICROSCOPY                                                   
AUTHOR    Y.ZHU,W.L.WANG,D.YU,Q.OUYANG,Y.LU,Y.MAO                               
REVDAT   1   18-JUL-18 5VFT    0                                                
JRNL        AUTH   Y.ZHU,W.L.WANG,D.YU,Q.OUYANG,Y.LU,Y.MAO                      
JRNL        TITL   STRUCTURAL MECHANISM FOR NUCLEOTIDE-DRIVEN REMODELING OF THE 
JRNL        TITL 2 AAA-ATPASE UNFOLDASE IN THE ACTIVATED HUMAN 26S PROTEASOME.  
JRNL        REF    NAT COMMUN                    V.   9  1360 2018              
JRNL        REFN                   ESSN 2041-1723                               
JRNL        PMID   29636472                                                     
JRNL        DOI    10.1038/S41467-018-03785-W                                   
REMARK   2                                                                      
REMARK   2 RESOLUTION.    7.00 ANGSTROMS.                                       
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   SOFTWARE PACKAGES      : GCTF, COOT, PHENIX, RELION, RELION,       
REMARK   3                            RELION, RELION                            
REMARK   3   RECONSTRUCTION SCHEMA  : NULL                                      
REMARK   3                                                                      
REMARK   3 EM MAP-MODEL FITTING AND REFINEMENT                                  
REMARK   3   PDB ENTRY                    : NULL                                
REMARK   3   REFINEMENT SPACE             : NULL                                
REMARK   3   REFINEMENT PROTOCOL          : NULL                                
REMARK   3   REFINEMENT TARGET            : NULL                                
REMARK   3   OVERALL ANISOTROPIC B VALUE  : NULL                                
REMARK   3                                                                      
REMARK   3 FITTING PROCEDURE : NULL                                             
REMARK   3                                                                      
REMARK   3 EM IMAGE RECONSTRUCTION STATISTICS                                   
REMARK   3   NOMINAL PIXEL SIZE (ANGSTROMS)    : NULL                           
REMARK   3   ACTUAL PIXEL SIZE  (ANGSTROMS)    : NULL                           
REMARK   3   EFFECTIVE RESOLUTION (ANGSTROMS)  : 7.000                          
REMARK   3   NUMBER OF PARTICLES               : 15536                          
REMARK   3   CTF CORRECTION METHOD             : PHASE FLIPPING AND AMPLITUDE   
REMARK   3                                       CORRECTION                     
REMARK   3                                                                      
REMARK   3 EM RECONSTRUCTION MAGNIFICATION CALIBRATION: NULL                    
REMARK   3                                                                      
REMARK   3 OTHER DETAILS: NULL                                                  
REMARK   4                                                                      
REMARK   4 5VFT COMPLIES WITH FORMAT V. 3.30, 13-JUL-11                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 11-APR-17.                  
REMARK 100 THE DEPOSITION ID IS D_1000227363.                                   
REMARK 245                                                                      
REMARK 245 EXPERIMENTAL DETAILS                                                 
REMARK 245   RECONSTRUCTION METHOD          : SINGLE PARTICLE                   
REMARK 245   SPECIMEN TYPE                  : NULL                              
REMARK 245                                                                      
REMARK 245 ELECTRON MICROSCOPE SAMPLE                                           
REMARK 245   SAMPLE TYPE                    : PARTICLE                          
REMARK 245   PARTICLE TYPE                  : POINT                             
REMARK 245   NAME OF SAMPLE                 : 26S PROTEASOME BOUND TO ATP       
REMARK 245                                    -GAMMAS                           
REMARK 245   SAMPLE CONCENTRATION (MG ML-1) : NULL                              
REMARK 245   SAMPLE SUPPORT DETAILS         : NULL                              
REMARK 245   SAMPLE VITRIFICATION DETAILS   : NULL                              
REMARK 245   SAMPLE BUFFER                  : NULL                              
REMARK 245   PH                             : 7.50                              
REMARK 245   SAMPLE DETAILS                 : NULL                              
REMARK 245                                                                      
REMARK 245 DATA ACQUISITION                                                     
REMARK 245   DATE OF EXPERIMENT                : NULL                           
REMARK 245   NUMBER OF MICROGRAPHS-IMAGES      : NULL                           
REMARK 245   TEMPERATURE (KELVIN)              : NULL                           
REMARK 245   MICROSCOPE MODEL                  : FEI TECNAI ARCTICA             
REMARK 245   DETECTOR TYPE                     : GATAN K2 SUMMIT (4K X 4K)      
REMARK 245   MINIMUM DEFOCUS (NM)              : NULL                           
REMARK 245   MAXIMUM DEFOCUS (NM)              : NULL                           
REMARK 245   MINIMUM TILT ANGLE (DEGREES)      : NULL                           
REMARK 245   MAXIMUM TILT ANGLE (DEGREES)      : NULL                           
REMARK 245   NOMINAL CS                        : NULL                           
REMARK 245   IMAGING MODE                      : BRIGHT FIELD                   
REMARK 245   ELECTRON DOSE (ELECTRONS NM**-2)  : 30.00                          
REMARK 245   ILLUMINATION MODE                 : FLOOD BEAM                     
REMARK 245   NOMINAL MAGNIFICATION             : NULL                           
REMARK 245   CALIBRATED MAGNIFICATION          : NULL                           
REMARK 245   SOURCE                            : FIELD EMISSION GUN             
REMARK 245   ACCELERATION VOLTAGE (KV)         : 200                            
REMARK 245   IMAGING DETAILS                   : NULL                           
REMARK 247                                                                      
REMARK 247 ELECTRON MICROSCOPY                                                  
REMARK 247  THE COORDINATES IN THIS ENTRY WERE GENERATED FROM ELECTRON          
REMARK 247  MICROSCOPY DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE              
REMARK 247  THAT CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES           
REMARK 247  ON THESE RECORDS ARE MEANINGLESS EXCEPT FOR THE CALCULATION         
REMARK 247  OF THE STRUCTURE FACTORS.                                           
REMARK 300                                                                      
REMARK 300 BIOMOLECULE: 1                                                       
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM                
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN                  
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON               
REMARK 300 BURIED SURFACE AREA.                                                 
REMARK 350                                                                      
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN           
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE                
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS          
REMARK 350 GIVEN BELOW.  BOTH NON-CRYSTALLOGRAPHIC AND                          
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.                               
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 1                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: 46-MERIC                          
REMARK 350 APPLY THE FOLLOWING TO CHAINS: U, V, W, X, Y, Z, a, b, c, d,         
REMARK 350                    AND CHAINS: e, A, B, C, D, E, F, G, H,            
REMARK 350                    AND CHAINS: I, J, K, L, M, N, O, P, Q, R,         
REMARK 350                    AND CHAINS: S, T, g, h, i, j, k, l, m,            
REMARK 350                    AND CHAINS: n, o, p, q, r, s, t, f                
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 465                                                                      
REMARK 465 MISSING RESIDUES                                                     
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE                       
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)                
REMARK 465                                                                      
REMARK 465   M RES C SSSEQI                                                     
REMARK 465     VAL U   271                                                      
REMARK 465     GLY U   272                                                      
REMARK 465     THR U   273                                                      
REMARK 465     PRO U   274                                                      
REMARK 465     ILE U   275                                                      
REMARK 465     ALA U   276                                                      
REMARK 465     SER U   277                                                      
REMARK 465     VAL U   278                                                      
REMARK 465     PRO U   279                                                      
REMARK 465     GLY U   280                                                      
REMARK 465     SER U   281                                                      
REMARK 465     THR U   282                                                      
REMARK 465     ASN U   283                                                      
REMARK 465     THR U   284                                                      
REMARK 465     GLY U   285                                                      
REMARK 465     THR U   286                                                      
REMARK 465     VAL U   287                                                      
REMARK 465     PRO U   288                                                      
REMARK 465     GLY U   289                                                      
REMARK 465     SER U   290                                                      
REMARK 465     GLU U   291                                                      
REMARK 465     LYS U   292                                                      
REMARK 465     ASP U   293                                                      
REMARK 465     SER U   294                                                      
REMARK 465     ASP U   295                                                      
REMARK 465     SER U   296                                                      
REMARK 465     MET U   297                                                      
REMARK 465     GLU U   298                                                      
REMARK 465     THR U   299                                                      
REMARK 465     GLU U   300                                                      
REMARK 465     GLU U   301                                                      
REMARK 465     LYS U   302                                                      
REMARK 465     THR U   303                                                      
REMARK 465     SER U   304                                                      
REMARK 465     SER U   305                                                      
REMARK 465     ALA U   306                                                      
REMARK 465     PHE U   307                                                      
REMARK 465     VAL U   308                                                      
REMARK 465     GLY U   309                                                      
REMARK 465     LYS U   310                                                      
REMARK 465     THR U   311                                                      
REMARK 465     PRO U   312                                                      
REMARK 465     GLU U   313                                                      
REMARK 465     ALA U   314                                                      
REMARK 465     SER U   315                                                      
REMARK 465     PRO U   316                                                      
REMARK 465     GLU U   317                                                      
REMARK 465     PRO U   318                                                      
REMARK 465     LYS U   319                                                      
REMARK 465     ALA U   815                                                      
REMARK 465     PRO U   816                                                      
REMARK 465     LEU U   817                                                      
REMARK 465     GLU U   818                                                      
REMARK 465     VAL U   819                                                      
REMARK 465     PRO U   820                                                      
REMARK 465     LYS U   821                                                      
REMARK 465     GLU U   822                                                      
REMARK 465     LYS U   823                                                      
REMARK 465     GLU U   824                                                      
REMARK 465     LYS U   825                                                      
REMARK 465     GLU U   826                                                      
REMARK 465     LYS U   827                                                      
REMARK 465     VAL U   828                                                      
REMARK 465     SER U   829                                                      
REMARK 465     THR U   830                                                      
REMARK 465     ALA U   831                                                      
REMARK 465     VAL U   832                                                      
REMARK 465     LEU U   833                                                      
REMARK 465     SER U   834                                                      
REMARK 465     ILE U   835                                                      
REMARK 465     GLU U   845                                                      
REMARK 465     LYS U   846                                                      
REMARK 465     GLU U   847                                                      
REMARK 465     LYS U   848                                                      
REMARK 465     LYS U   849                                                      
REMARK 465     GLU U   850                                                      
REMARK 465     GLU U   851                                                      
REMARK 465     GLU U   852                                                      
REMARK 465     LYS U   853                                                      
REMARK 465     MET U   854                                                      
REMARK 465     GLU U   855                                                      
REMARK 465     VAL U   856                                                      
REMARK 465     ASP U   857                                                      
REMARK 465     GLU U   858                                                      
REMARK 465     ALA U   859                                                      
REMARK 465     GLU U   860                                                      
REMARK 465     LYS U   861                                                      
REMARK 465     LYS U   862                                                      
REMARK 465     GLU U   863                                                      
REMARK 465     GLU U   864                                                      
REMARK 465     LYS U   865                                                      
REMARK 465     GLU U   866                                                      
REMARK 465     LYS U   867                                                      
REMARK 465     LYS U   868                                                      
REMARK 465     LYS U   869                                                      
REMARK 465     GLU U   870                                                      
REMARK 465     PRO U   871                                                      
REMARK 465     GLU U   872                                                      
REMARK 465     PRO U   873                                                      
REMARK 465     ASN U   874                                                      
REMARK 465     PHE U   875                                                      
REMARK 465     GLN U   876                                                      
REMARK 465     LEU U   877                                                      
REMARK 465     LEU U   878                                                      
REMARK 465     ASP U   879                                                      
REMARK 465     MET W     1                                                      
REMARK 465     ALA W     2                                                      
REMARK 465     ASP W     3                                                      
REMARK 465     GLY W     4                                                      
REMARK 465     GLY W     5                                                      
REMARK 465     SER W     6                                                      
REMARK 465     GLU W     7                                                      
REMARK 465     ARG W     8                                                      
REMARK 465     ALA W     9                                                      
REMARK 465     ASP W    10                                                      
REMARK 465     GLY W    11                                                      
REMARK 465     ARG W    12                                                      
REMARK 465     ILE W    13                                                      
REMARK 465     VAL W    14                                                      
REMARK 465     LYS W    15                                                      
REMARK 465     MET W    16                                                      
REMARK 465     GLU W    17                                                      
REMARK 465     VAL W    18                                                      
REMARK 465     ASP W    19                                                      
REMARK 465     TYR W    20                                                      
REMARK 465     SER W    21                                                      
REMARK 465     ALA W    22                                                      
REMARK 465     THR W    23                                                      
REMARK 465     VAL W    24                                                      
REMARK 465     ASP W    25                                                      
REMARK 465     GLN W    26                                                      
REMARK 465     ARG W    27                                                      
REMARK 465     LEU W    28                                                      
REMARK 465     PRO W    29                                                      
REMARK 465     GLU W    30                                                      
REMARK 465     CYS W    31                                                      
REMARK 465     ALA W    32                                                      
REMARK 465     LYS W    33                                                      
REMARK 465     LEU W    34                                                      
REMARK 465     ALA W    35                                                      
REMARK 465     LYS W    36                                                      
REMARK 465     GLU W    37                                                      
REMARK 465     GLY W    38                                                      
REMARK 465     ARG W    39                                                      
REMARK 465     LEU W    40                                                      
REMARK 465     GLN W    41                                                      
REMARK 465     GLU W    42                                                      
REMARK 465     VAL W    43                                                      
REMARK 465     ILE W    44                                                      
REMARK 465     GLU W    45                                                      
REMARK 465     THR W    46                                                      
REMARK 465     LEU W    47                                                      
REMARK 465     LEU W    48                                                      
REMARK 465     SER W    49                                                      
REMARK 465     LEU W    50                                                      
REMARK 465     GLU W    51                                                      
REMARK 465     LYS W    52                                                      
REMARK 465     GLN W    53                                                      
REMARK 465     THR W    54                                                      
REMARK 465     ARG W    55                                                      
REMARK 465     THR W    56                                                      
REMARK 465     ALA W    57                                                      
REMARK 465     SER W    58                                                      
REMARK 465     ASP W    59                                                      
REMARK 465     MET W    60                                                      
REMARK 465     VAL W    61                                                      
REMARK 465     SER W    62                                                      
REMARK 465     THR W    63                                                      
REMARK 465     SER W    64                                                      
REMARK 465     ARG W    65                                                      
REMARK 465     ILE W    66                                                      
REMARK 465     LEU W    67                                                      
REMARK 465     VAL W    68                                                      
REMARK 465     ALA W    69                                                      
REMARK 465     VAL W    70                                                      
REMARK 465     VAL W    71                                                      
REMARK 465     LYS W    72                                                      
REMARK 465     MET W    73                                                      
REMARK 465     CYS W    74                                                      
REMARK 465     TYR W    75                                                      
REMARK 465     GLU W    76                                                      
REMARK 465     ALA W    77                                                      
REMARK 465     LYS W    78                                                      
REMARK 465     GLU W    79                                                      
REMARK 465     TRP W    80                                                      
REMARK 465     ASP W    81                                                      
REMARK 465     LEU W    82                                                      
REMARK 465     LEU W    83                                                      
REMARK 465     ASN W    84                                                      
REMARK 465     GLU W    85                                                      
REMARK 465     ASN W    86                                                      
REMARK 465     ILE W    87                                                      
REMARK 465     MET W    88                                                      
REMARK 465     LEU W    89                                                      
REMARK 465     LEU W    90                                                      
REMARK 465     SER W    91                                                      
REMARK 465     LYS W    92                                                      
REMARK 465     ARG W    93                                                      
REMARK 465     ARG W    94                                                      
REMARK 465     SER W    95                                                      
REMARK 465     GLN W    96                                                      
REMARK 465     LEU W    97                                                      
REMARK 465     LYS W    98                                                      
REMARK 465     GLN W    99                                                      
REMARK 465     ALA W   100                                                      
REMARK 465     VAL W   101                                                      
REMARK 465     ALA W   102                                                      
REMARK 465     LYS W   103                                                      
REMARK 465     MET W   104                                                      
REMARK 465     VAL W   105                                                      
REMARK 465     GLN W   106                                                      
REMARK 465     GLN W   107                                                      
REMARK 465     CYS W   108                                                      
REMARK 465     CYS W   109                                                      
REMARK 465     THR W   110                                                      
REMARK 465     TYR W   111                                                      
REMARK 465     VAL W   112                                                      
REMARK 465     GLU W   113                                                      
REMARK 465     GLU W   114                                                      
REMARK 465     ILE W   115                                                      
REMARK 465     THR W   116                                                      
REMARK 465     ASP W   117                                                      
REMARK 465     LEU W   118                                                      
REMARK 465     PRO W   119                                                      
REMARK 465     ILE W   120                                                      
REMARK 465     LYS W   121                                                      
REMARK 465     LEU W   122                                                      
REMARK 465     ARG W   123                                                      
REMARK 465     LEU W   124                                                      
REMARK 465     ILE W   125                                                      
REMARK 465     ASP W   126                                                      
REMARK 465     THR W   127                                                      
REMARK 465     LEU W   128                                                      
REMARK 465     ARG W   129                                                      
REMARK 465     MET W   130                                                      
REMARK 465     VAL W   131                                                      
REMARK 465     THR W   132                                                      
REMARK 465     GLU W   133                                                      
REMARK 465     GLY W   134                                                      
REMARK 465     LYS W   135                                                      
REMARK 465     ILE W   136                                                      
REMARK 465     TYR W   137                                                      
REMARK 465     VAL W   138                                                      
REMARK 465     GLU W   139                                                      
REMARK 465     ILE W   140                                                      
REMARK 465     GLU W   141                                                      
REMARK 465     ARG W   142                                                      
REMARK 465     ALA W   143                                                      
REMARK 465     ARG W   144                                                      
REMARK 465     LEU W   145                                                      
REMARK 465     THR W   146                                                      
REMARK 465     LYS W   147                                                      
REMARK 465     THR W   148                                                      
REMARK 465     LEU W   149                                                      
REMARK 465     ALA W   150                                                      
REMARK 465     THR W   151                                                      
REMARK 465     ILE W   152                                                      
REMARK 465     LYS W   153                                                      
REMARK 465     GLU W   154                                                      
REMARK 465     GLN W   155                                                      
REMARK 465     ASN W   156                                                      
REMARK 465     GLY W   157                                                      
REMARK 465     ASP W   158                                                      
REMARK 465     VAL W   159                                                      
REMARK 465     LYS W   160                                                      
REMARK 465     GLU W   161                                                      
REMARK 465     ALA W   162                                                      
REMARK 465     ALA W   163                                                      
REMARK 465     SER W   164                                                      
REMARK 465     ILE W   165                                                      
REMARK 465     LEU W   166                                                      
REMARK 465     GLN W   167                                                      
REMARK 465     GLU W   168                                                      
REMARK 465     LEU W   169                                                      
REMARK 465     GLN W   170                                                      
REMARK 465     VAL W   171                                                      
REMARK 465     GLU W   172                                                      
REMARK 465     THR W   173                                                      
REMARK 465     TYR W   174                                                      
REMARK 465     GLY W   175                                                      
REMARK 465     SER W   176                                                      
REMARK 465     MET W   177                                                      
REMARK 465     GLU W   178                                                      
REMARK 465     LYS W   179                                                      
REMARK 465     LYS W   180                                                      
REMARK 465     GLU W   181                                                      
REMARK 465     ARG W   182                                                      
REMARK 465     VAL W   183                                                      
REMARK 465     GLU W   184                                                      
REMARK 465     PHE W   185                                                      
REMARK 465     ILE W   186                                                      
REMARK 465     LEU W   187                                                      
REMARK 465     GLU W   188                                                      
REMARK 465     GLN W   189                                                      
REMARK 465     MET W   190                                                      
REMARK 465     ARG W   191                                                      
REMARK 465     LEU W   192                                                      
REMARK 465     CYS W   193                                                      
REMARK 465     LEU W   194                                                      
REMARK 465     ALA W   195                                                      
REMARK 465     VAL W   196                                                      
REMARK 465     LYS W   197                                                      
REMARK 465     ASP W   198                                                      
REMARK 465     TYR W   199                                                      
REMARK 465     ILE W   200                                                      
REMARK 465     ARG W   201                                                      
REMARK 465     THR W   202                                                      
REMARK 465     GLN W   203                                                      
REMARK 465     ILE W   204                                                      
REMARK 465     ILE W   205                                                      
REMARK 465     SER W   206                                                      
REMARK 465     LYS W   207                                                      
REMARK 465     LYS W   208                                                      
REMARK 465     ILE W   209                                                      
REMARK 465     ASN W   210                                                      
REMARK 465     THR W   211                                                      
REMARK 465     LYS W   212                                                      
REMARK 465     PHE W   213                                                      
REMARK 465     PHE W   214                                                      
REMARK 465     GLN W   215                                                      
REMARK 465     GLU W   216                                                      
REMARK 465     GLU W   217                                                      
REMARK 465     ASN W   218                                                      
REMARK 465     THR W   219                                                      
REMARK 465     GLU W   220                                                      
REMARK 465     VAL X    43                                                      
REMARK 465     GLN X    44                                                      
REMARK 465     VAL X    45                                                      
REMARK 465     LYS X    46                                                      
REMARK 465     GLU X    47                                                      
REMARK 465     GLN X    48                                                      
REMARK 465     SER X    49                                                      
REMARK 465     ILE X    50                                                      
REMARK 465     LEU X    51                                                      
REMARK 465     GLU X    52                                                      
REMARK 465     LEU X    53                                                      
REMARK 465     GLY X    54                                                      
REMARK 465     SER X    55                                                      
REMARK 465     LEU X    56                                                      
REMARK 465     LEU X    57                                                      
REMARK 465     ALA X    58                                                      
REMARK 465     LYS X    59                                                      
REMARK 465     THR X    60                                                      
REMARK 465     GLY X    61                                                      
REMARK 465     GLN X    62                                                      
REMARK 465     ALA X    63                                                      
REMARK 465     ALA X    64                                                      
REMARK 465     GLU X    65                                                      
REMARK 465     LEU X    66                                                      
REMARK 465     GLY X    67                                                      
REMARK 465     GLY X    68                                                      
REMARK 465     LEU X    69                                                      
REMARK 465     LEU X    70                                                      
REMARK 465     LYS X    71                                                      
REMARK 465     TYR X    72                                                      
REMARK 465     VAL X    73                                                      
REMARK 465     ARG X    74                                                      
REMARK 465     PRO X    75                                                      
REMARK 465     PHE X    76                                                      
REMARK 465     LEU X    77                                                      
REMARK 465     ASN X    78                                                      
REMARK 465     SER X    79                                                      
REMARK 465     ILE X    80                                                      
REMARK 465     SER X    81                                                      
REMARK 465     LYS X    82                                                      
REMARK 465     ALA X    83                                                      
REMARK 465     LYS X    84                                                      
REMARK 465     ALA X    85                                                      
REMARK 465     ALA X    86                                                      
REMARK 465     ARG X    87                                                      
REMARK 465     LEU X    88                                                      
REMARK 465     VAL X    89                                                      
REMARK 465     ARG X    90                                                      
REMARK 465     SER X    91                                                      
REMARK 465     LEU X    92                                                      
REMARK 465     LEU X    93                                                      
REMARK 465     ASP X    94                                                      
REMARK 465     LEU X    95                                                      
REMARK 465     PHE X    96                                                      
REMARK 465     LEU X    97                                                      
REMARK 465     ASP X    98                                                      
REMARK 465     MET X    99                                                      
REMARK 465     GLU X   100                                                      
REMARK 465     ALA X   101                                                      
REMARK 465     ALA X   102                                                      
REMARK 465     THR X   103                                                      
REMARK 465     GLY X   104                                                      
REMARK 465     GLN X   105                                                      
REMARK 465     GLU X   106                                                      
REMARK 465     VAL X   107                                                      
REMARK 465     GLU X   108                                                      
REMARK 465     LEU X   109                                                      
REMARK 465     CYS X   110                                                      
REMARK 465     LEU X   111                                                      
REMARK 465     GLU X   112                                                      
REMARK 465     CYS X   113                                                      
REMARK 465     ILE X   114                                                      
REMARK 465     GLU X   115                                                      
REMARK 465     TRP X   116                                                      
REMARK 465     ALA X   117                                                      
REMARK 465     LYS X   118                                                      
REMARK 465     SER X   119                                                      
REMARK 465     GLU X   120                                                      
REMARK 465     LYS X   121                                                      
REMARK 465     ARG X   122                                                      
REMARK 465     THR X   123                                                      
REMARK 465     PHE X   124                                                      
REMARK 465     LEU X   125                                                      
REMARK 465     ARG X   126                                                      
REMARK 465     GLN X   127                                                      
REMARK 465     ALA X   128                                                      
REMARK 465     LEU X   129                                                      
REMARK 465     GLU X   130                                                      
REMARK 465     ALA X   131                                                      
REMARK 465     ARG X   132                                                      
REMARK 465     LEU X   133                                                      
REMARK 465     VAL X   134                                                      
REMARK 465     SER X   135                                                      
REMARK 465     LEU X   136                                                      
REMARK 465     TYR X   137                                                      
REMARK 465     PHE X   138                                                      
REMARK 465     ASP X   139                                                      
REMARK 465     THR X   140                                                      
REMARK 465     LYS X   141                                                      
REMARK 465     ARG X   142                                                      
REMARK 465     TYR X   143                                                      
REMARK 465     GLN X   144                                                      
REMARK 465     GLU X   145                                                      
REMARK 465     ALA X   146                                                      
REMARK 465     LEU X   147                                                      
REMARK 465     HIS X   148                                                      
REMARK 465     LEU X   149                                                      
REMARK 465     GLY X   150                                                      
REMARK 465     SER X   151                                                      
REMARK 465     GLN X   152                                                      
REMARK 465     LEU X   153                                                      
REMARK 465     LEU X   154                                                      
REMARK 465     ARG X   155                                                      
REMARK 465     GLU X   156                                                      
REMARK 465     LEU X   157                                                      
REMARK 465     LYS X   158                                                      
REMARK 465     LYS X   159                                                      
REMARK 465     MET X   160                                                      
REMARK 465     ASP X   161                                                      
REMARK 465     ASP X   162                                                      
REMARK 465     LYS X   163                                                      
REMARK 465     ALA X   164                                                      
REMARK 465     LEU X   165                                                      
REMARK 465     LEU X   166                                                      
REMARK 465     VAL X   167                                                      
REMARK 465     GLU X   168                                                      
REMARK 465     VAL X   169                                                      
REMARK 465     GLN X   170                                                      
REMARK 465     LEU X   171                                                      
REMARK 465     LEU X   172                                                      
REMARK 465     GLU X   173                                                      
REMARK 465     SER X   174                                                      
REMARK 465     LYS X   175                                                      
REMARK 465     THR X   176                                                      
REMARK 465     TYR X   177                                                      
REMARK 465     HIS X   178                                                      
REMARK 465     ALA X   179                                                      
REMARK 465     LEU X   180                                                      
REMARK 465     SER X   181                                                      
REMARK 465     ASN X   182                                                      
REMARK 465     LEU X   183                                                      
REMARK 465     PRO X   184                                                      
REMARK 465     LYS X   185                                                      
REMARK 465     ALA X   186                                                      
REMARK 465     ARG X   187                                                      
REMARK 465     ALA X   188                                                      
REMARK 465     ALA X   189                                                      
REMARK 465     LEU X   190                                                      
REMARK 465     THR X   191                                                      
REMARK 465     SER X   192                                                      
REMARK 465     ALA X   193                                                      
REMARK 465     ARG X   194                                                      
REMARK 465     THR X   195                                                      
REMARK 465     THR X   196                                                      
REMARK 465     ALA X   197                                                      
REMARK 465     ASN X   198                                                      
REMARK 465     ALA X   199                                                      
REMARK 465     ILE X   200                                                      
REMARK 465     TYR X   201                                                      
REMARK 465     CYS X   202                                                      
REMARK 465     PRO X   203                                                      
REMARK 465     PRO X   204                                                      
REMARK 465     LYS X   205                                                      
REMARK 465     LEU X   206                                                      
REMARK 465     GLN X   207                                                      
REMARK 465     ALA X   208                                                      
REMARK 465     THR X   209                                                      
REMARK 465     LEU X   210                                                      
REMARK 465     ASP X   211                                                      
REMARK 465     MET X   212                                                      
REMARK 465     GLN X   213                                                      
REMARK 465     SER X   214                                                      
REMARK 465     GLY X   215                                                      
REMARK 465     ILE X   216                                                      
REMARK 465     ILE X   217                                                      
REMARK 465     HIS X   218                                                      
REMARK 465     ALA X   219                                                      
REMARK 465     ALA X   220                                                      
REMARK 465     GLU X   221                                                      
REMARK 465     GLU X   222                                                      
REMARK 465     LYS X   223                                                      
REMARK 465     ASP X   224                                                      
REMARK 465     TRP X   225                                                      
REMARK 465     LYS X   226                                                      
REMARK 465     THR X   227                                                      
REMARK 465     ALA X   228                                                      
REMARK 465     TYR X   229                                                      
REMARK 465     SER X   230                                                      
REMARK 465     TYR X   231                                                      
REMARK 465     PHE X   232                                                      
REMARK 465     TYR X   233                                                      
REMARK 465     GLU X   234                                                      
REMARK 465     ALA X   235                                                      
REMARK 465     PHE X   236                                                      
REMARK 465     GLU X   237                                                      
REMARK 465     GLY X   238                                                      
REMARK 465     TYR X   239                                                      
REMARK 465     ASP X   240                                                      
REMARK 465     SER X   241                                                      
REMARK 465     ILE X   242                                                      
REMARK 465     ASP X   243                                                      
REMARK 465     SER X   244                                                      
REMARK 465     PRO X   245                                                      
REMARK 465     LYS X   246                                                      
REMARK 465     ALA X   247                                                      
REMARK 465     ILE X   248                                                      
REMARK 465     THR X   249                                                      
REMARK 465     SER X   250                                                      
REMARK 465     LEU X   251                                                      
REMARK 465     LYS X   252                                                      
REMARK 465     TYR X   253                                                      
REMARK 465     MET X   254                                                      
REMARK 465     LEU X   255                                                      
REMARK 465     LEU X   256                                                      
REMARK 465     CYS X   257                                                      
REMARK 465     LYS X   258                                                      
REMARK 465     ILE X   259                                                      
REMARK 465     MET X   260                                                      
REMARK 465     LEU X   261                                                      
REMARK 465     ASN X   262                                                      
REMARK 465     THR X   263                                                      
REMARK 465     PRO X   264                                                      
REMARK 465     GLU X   265                                                      
REMARK 465     ASP X   266                                                      
REMARK 465     VAL X   267                                                      
REMARK 465     GLN X   268                                                      
REMARK 465     ALA X   269                                                      
REMARK 465     LEU X   270                                                      
REMARK 465     VAL X   271                                                      
REMARK 465     SER X   272                                                      
REMARK 465     GLY X   273                                                      
REMARK 465     LYS X   274                                                      
REMARK 465     LEU X   275                                                      
REMARK 465     ALA X   276                                                      
REMARK 465     LEU X   277                                                      
REMARK 465     ARG X   278                                                      
REMARK 465     TYR X   279                                                      
REMARK 465     ALA X   280                                                      
REMARK 465     GLY X   281                                                      
REMARK 465     ARG X   282                                                      
REMARK 465     GLN X   283                                                      
REMARK 465     THR X   284                                                      
REMARK 465     GLU X   285                                                      
REMARK 465     ALA X   286                                                      
REMARK 465     LEU X   287                                                      
REMARK 465     LYS X   288                                                      
REMARK 465     CYS X   289                                                      
REMARK 465     VAL X   290                                                      
REMARK 465     ALA X   291                                                      
REMARK 465     GLN X   292                                                      
REMARK 465     ALA X   293                                                      
REMARK 465     SER X   294                                                      
REMARK 465     LYS X   295                                                      
REMARK 465     ASN X   296                                                      
REMARK 465     ARG X   297                                                      
REMARK 465     SER X   298                                                      
REMARK 465     LEU X   299                                                      
REMARK 465     ALA X   300                                                      
REMARK 465     ASP X   301                                                      
REMARK 465     PHE X   302                                                      
REMARK 465     GLU X   303                                                      
REMARK 465     LYS X   304                                                      
REMARK 465     ALA X   305                                                      
REMARK 465     LEU X   306                                                      
REMARK 465     THR X   307                                                      
REMARK 465     ASP X   308                                                      
REMARK 465     TYR X   309                                                      
REMARK 465     ARG X   310                                                      
REMARK 465     ALA X   311                                                      
REMARK 465     GLU X   312                                                      
REMARK 465     LEU X   313                                                      
REMARK 465     ARG X   314                                                      
REMARK 465     ASP X   315                                                      
REMARK 465     ASP X   316                                                      
REMARK 465     PRO X   317                                                      
REMARK 465     ILE X   318                                                      
REMARK 465     ILE X   319                                                      
REMARK 465     SER X   320                                                      
REMARK 465     THR X   321                                                      
REMARK 465     HIS X   322                                                      
REMARK 465     LEU X   323                                                      
REMARK 465     ALA X   324                                                      
REMARK 465     LYS X   325                                                      
REMARK 465     LEU X   326                                                      
REMARK 465     TYR X   327                                                      
REMARK 465     ASP X   328                                                      
REMARK 465     ASN X   329                                                      
REMARK 465     LEU X   330                                                      
REMARK 465     LEU X   331                                                      
REMARK 465     GLU X   332                                                      
REMARK 465     GLN X   333                                                      
REMARK 465     ASN X   334                                                      
REMARK 465     LEU X   335                                                      
REMARK 465     ILE X   336                                                      
REMARK 465     ARG X   337                                                      
REMARK 465     VAL X   338                                                      
REMARK 465     ILE X   339                                                      
REMARK 465     GLU X   340                                                      
REMARK 465     PRO X   341                                                      
REMARK 465     UNK e    10                                                      
REMARK 465     UNK e    11                                                      
REMARK 465     UNK e    12                                                      
REMARK 465     UNK e    13                                                      
REMARK 465     UNK e    14                                                      
REMARK 465     UNK e    15                                                      
REMARK 465     UNK e    16                                                      
REMARK 465     UNK e    17                                                      
REMARK 465     UNK e    18                                                      
REMARK 465     UNK e    19                                                      
REMARK 465     UNK e    20                                                      
REMARK 465     UNK e    21                                                      
REMARK 465     UNK e    22                                                      
REMARK 465     UNK e    23                                                      
REMARK 465     UNK e    24                                                      
REMARK 465     UNK e    25                                                      
REMARK 465     UNK e    26                                                      
REMARK 465     UNK e    27                                                      
REMARK 465     UNK e    28                                                      
REMARK 465     UNK e    29                                                      
REMARK 465     UNK e    30                                                      
REMARK 465     UNK e    31                                                      
REMARK 465     UNK e    32                                                      
REMARK 465     UNK e    33                                                      
REMARK 465     UNK e    34                                                      
REMARK 465     UNK e    35                                                      
REMARK 465     UNK e    36                                                      
REMARK 465     UNK e    37                                                      
REMARK 465     UNK e    38                                                      
REMARK 465     UNK e    39                                                      
REMARK 465     UNK e    40                                                      
REMARK 465     UNK e    41                                                      
REMARK 465     UNK e    42                                                      
REMARK 465     UNK e    43                                                      
REMARK 465     UNK e    44                                                      
REMARK 465     UNK e    45                                                      
REMARK 465     UNK e    46                                                      
REMARK 465     UNK e    47                                                      
REMARK 465     UNK e    48                                                      
REMARK 465     UNK e    49                                                      
REMARK 465     UNK e    50                                                      
REMARK 465     UNK e    51                                                      
REMARK 465     UNK e    52                                                      
REMARK 465     UNK e    53                                                      
REMARK 465     UNK e    54                                                      
REMARK 465     UNK e    55                                                      
REMARK 465     GLN F   104                                                      
REMARK 465     GLU F   105                                                      
REMARK 465     GLU F   106                                                      
REMARK 465     ASP F   107                                                      
REMARK 465     GLY F   108                                                      
REMARK 465     ALA F   109                                                      
REMARK 465     ASN F   110                                                      
REMARK 465     ILE F   111                                                      
REMARK 465     ASP F   112                                                      
REMARK 465     LEU F   113                                                      
REMARK 465     ASP F   114                                                      
REMARK 465     LYS J   241                                                      
REMARK 465     LYS J   242                                                      
REMARK 465     LYS J   243                                                      
REMARK 465     GLN J   244                                                      
REMARK 465     ALA K   128                                                      
REMARK 465     ASP K   129                                                      
REMARK 465     PRO K   130                                                      
REMARK 465     GLY K   131                                                      
REMARK 465     ALA K   132                                                      
REMARK 465     MET K   133                                                      
REMARK 465     SER M     1                                                      
REMARK 465     SER M     2                                                      
REMARK 465     ILE M     3                                                      
REMARK 465     GLY M     4                                                      
REMARK 465     GLU M   245                                                      
REMARK 465     LYS j   241                                                      
REMARK 465     LYS j   242                                                      
REMARK 465     LYS j   243                                                      
REMARK 465     GLN j   244                                                      
REMARK 465     ALA k   128                                                      
REMARK 465     ASP k   129                                                      
REMARK 465     PRO k   130                                                      
REMARK 465     GLY k   131                                                      
REMARK 465     ALA k   132                                                      
REMARK 465     MET k   133                                                      
REMARK 465     SER m     1                                                      
REMARK 465     SER m     2                                                      
REMARK 465     ILE m     3                                                      
REMARK 465     GLY m     4                                                      
REMARK 465     GLU m   245                                                      
REMARK 465     MET f     1                                                      
REMARK 465     GLU f     2                                                      
REMARK 465     GLU f     3                                                      
REMARK 465     GLY f     4                                                      
REMARK 465     GLY f     5                                                      
REMARK 465     LEU f    56                                                      
REMARK 465     GLU f    57                                                      
REMARK 465     MET f    58                                                      
REMARK 465     LEU f    59                                                      
REMARK 465     VAL f    60                                                      
REMARK 465     GLU f    61                                                      
REMARK 465     ARG f    62                                                      
REMARK 465     LEU f    63                                                      
REMARK 465     GLY f    64                                                      
REMARK 465     GLU f    65                                                      
REMARK 465     LYS f    66                                                      
REMARK 465     ASP f    67                                                      
REMARK 465     THR f    68                                                      
REMARK 465     SER f    69                                                      
REMARK 465     GLY f   104                                                      
REMARK 465     LYS f   105                                                      
REMARK 465     LEU f   106                                                      
REMARK 465     LYS f   107                                                      
REMARK 465     GLU f   108                                                      
REMARK 465     ILE f   109                                                      
REMARK 465     TYR f   110                                                      
REMARK 465     GLU f   111                                                      
REMARK 465     ASN f   112                                                      
REMARK 465     MET f   113                                                      
REMARK 465     ALA f   114                                                      
REMARK 465     PRO f   115                                                      
REMARK 465     GLY f   116                                                      
REMARK 465     GLU f   117                                                      
REMARK 465     SER f   147                                                      
REMARK 465     GLN f   148                                                      
REMARK 465     GLU f   149                                                      
REMARK 465     GLU f   150                                                      
REMARK 465     LEU f   151                                                      
REMARK 465     ALA f   152                                                      
REMARK 465     SER f   153                                                      
REMARK 465     TRP f   154                                                      
REMARK 465     GLY f   155                                                      
REMARK 465     HIS f   156                                                      
REMARK 465     GLU f   157                                                      
REMARK 465     TYR f   158                                                      
REMARK 465     VAL f   159                                                      
REMARK 465     ARG f   160                                                      
REMARK 465     HIS f   161                                                      
REMARK 465     LEU f   162                                                      
REMARK 465     TYR f   194                                                      
REMARK 465     ASN f   195                                                      
REMARK 465     MET f   196                                                      
REMARK 465     ALA f   197                                                      
REMARK 465     HIS f   198                                                      
REMARK 465     ASN f   199                                                      
REMARK 465     ALA f   200                                                      
REMARK 465     GLU f   201                                                      
REMARK 465     HIS f   202                                                      
REMARK 465     GLU f   203                                                      
REMARK 465     ALA f   204                                                      
REMARK 465     CYS f   205                                                      
REMARK 465     ASP f   206                                                      
REMARK 465     VAL f   290                                                      
REMARK 465     GLN f   291                                                      
REMARK 465     LYS f   292                                                      
REMARK 465     GLN f   293                                                      
REMARK 465     MET f   294                                                      
REMARK 465     ALA f   295                                                      
REMARK 465     PHE f   296                                                      
REMARK 465     ALA f   383                                                      
REMARK 465     ALA f   384                                                      
REMARK 465     PHE f   385                                                      
REMARK 465     GLY f   386                                                      
REMARK 465     SER f   700                                                      
REMARK 465     ASN f   701                                                      
REMARK 465     PRO f   702                                                      
REMARK 465     ARG f   703                                                      
REMARK 465     LEU f   704                                                      
REMARK 465     ASN f   705                                                      
REMARK 465     ILE f   706                                                      
REMARK 465     LEU f   707                                                      
REMARK 465     ASP f   708                                                      
REMARK 465     THR f   709                                                      
REMARK 465     LEU f   710                                                      
REMARK 465     SER f   711                                                      
REMARK 465     LYS f   712                                                      
REMARK 465     PHE f   713                                                      
REMARK 465     MET f   729                                                      
REMARK 465     GLY f   730                                                      
REMARK 465     MET f   731                                                      
REMARK 465     VAL f   732                                                      
REMARK 465     GLY f   733                                                      
REMARK 465     SER f   734                                                      
REMARK 465     GLY f   735                                                      
REMARK 465     THR f   736                                                      
REMARK 465     ASN f   737                                                      
REMARK 465     ASN f   738                                                      
REMARK 465     ASP f   755                                                      
REMARK 465     PRO f   756                                                      
REMARK 465     ASN f   757                                                      
REMARK 465     ASN f   758                                                      
REMARK 465     LEU f   759                                                      
REMARK 465     PHE f   760                                                      
REMARK 465     MET f   761                                                      
REMARK 465     VAL f   762                                                      
REMARK 465     ARG f   763                                                      
REMARK 465     LEU f   764                                                      
REMARK 465     ALA f   765                                                      
REMARK 465     GLN f   766                                                      
REMARK 465     GLY f   767                                                      
REMARK 465     LEU f   768                                                      
REMARK 465     THR f   769                                                      
REMARK 465     HIS f   770                                                      
REMARK 465     LEU f   771                                                      
REMARK 465     GLY f   772                                                      
REMARK 465     ASP f   805                                                      
REMARK 465     VAL f   806                                                      
REMARK 465     ARG f   807                                                      
REMARK 465     ASN f   808                                                      
REMARK 465     ILE f   809                                                      
REMARK 465     ILE f   810                                                      
REMARK 465     LEU f   811                                                      
REMARK 465     GLY f   812                                                      
REMARK 465     LYS f   813                                                      
REMARK 465     SER f   814                                                      
REMARK 465     HIS f   815                                                      
REMARK 465     TYR f   816                                                      
REMARK 465     VAL f   817                                                      
REMARK 465     LEU f   818                                                      
REMARK 465     TYR f   819                                                      
REMARK 465     GLY f   820                                                      
REMARK 465     LEU f   821                                                      
REMARK 465     VAL f   822                                                      
REMARK 465     ALA f   823                                                      
REMARK 465     ALA f   824                                                      
REMARK 465     MET f   825                                                      
REMARK 465     GLN f   826                                                      
REMARK 465     PRO f   827                                                      
REMARK 465     ARG f   828                                                      
REMARK 465     MET f   829                                                      
REMARK 465     LEU f   830                                                      
REMARK 465     VAL f   831                                                      
REMARK 465     THR f   832                                                      
REMARK 465     PHE f   833                                                      
REMARK 465     ASP f   834                                                      
REMARK 465     GLU f   835                                                      
REMARK 465     GLU f   836                                                      
REMARK 465     LEU f   837                                                      
REMARK 465     ARG f   838                                                      
REMARK 465     PRO f   839                                                      
REMARK 465     LEU f   840                                                      
REMARK 465     PRO f   841                                                      
REMARK 465     VAL f   842                                                      
REMARK 465     SER f   843                                                      
REMARK 465     VAL f   844                                                      
REMARK 465     ARG f   845                                                      
REMARK 465     VAL f   846                                                      
REMARK 465     GLY f   847                                                      
REMARK 465     GLN f   848                                                      
REMARK 465     ALA f   849                                                      
REMARK 465     VAL f   850                                                      
REMARK 465     ASP f   851                                                      
REMARK 465     VAL f   852                                                      
REMARK 465     VAL f   853                                                      
REMARK 465     GLY f   854                                                      
REMARK 465     GLN f   855                                                      
REMARK 465     ALA f   856                                                      
REMARK 465     GLY f   857                                                      
REMARK 465     LYS f   858                                                      
REMARK 465     PRO f   859                                                      
REMARK 465     LYS f   860                                                      
REMARK 465     THR f   861                                                      
REMARK 465     ILE f   862                                                      
REMARK 465     THR f   863                                                      
REMARK 465     GLY f   864                                                      
REMARK 465     PHE f   865                                                      
REMARK 465     GLN f   866                                                      
REMARK 465     THR f   867                                                      
REMARK 465     HIS f   868                                                      
REMARK 465     THR f   869                                                      
REMARK 465     THR f   870                                                      
REMARK 465     PRO f   871                                                      
REMARK 465     VAL f   872                                                      
REMARK 465     LEU f   873                                                      
REMARK 465     LEU f   874                                                      
REMARK 465     ALA f   875                                                      
REMARK 465     HIS f   876                                                      
REMARK 465     GLY f   877                                                      
REMARK 465     GLU f   878                                                      
REMARK 465     ARG f   879                                                      
REMARK 465     ALA f   880                                                      
REMARK 465     GLU f   881                                                      
REMARK 465     LEU f   882                                                      
REMARK 465     ALA f   883                                                      
REMARK 465     THR f   884                                                      
REMARK 465     GLU f   885                                                      
REMARK 465     GLU f   886                                                      
REMARK 465     PHE f   887                                                      
REMARK 465     LEU f   888                                                      
REMARK 465     PRO f   889                                                      
REMARK 465     VAL f   890                                                      
REMARK 465     THR f   891                                                      
REMARK 465     PRO f   892                                                      
REMARK 465     ILE f   893                                                      
REMARK 465     LEU f   894                                                      
REMARK 465     GLU f   895                                                      
REMARK 465     GLY f   896                                                      
REMARK 465     PHE f   897                                                      
REMARK 465     VAL f   898                                                      
REMARK 465     ILE f   899                                                      
REMARK 465     LEU f   900                                                      
REMARK 465     ARG f   901                                                      
REMARK 465     LYS f   902                                                      
REMARK 465     ASN f   903                                                      
REMARK 465     PRO f   904                                                      
REMARK 465     ASN f   905                                                      
REMARK 465     TYR f   906                                                      
REMARK 465     ASP f   907                                                      
REMARK 465     LEU f   908                                                      
REMARK 470                                                                      
REMARK 470 MISSING ATOM                                                         
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;           
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;          
REMARK 470 I=INSERTION CODE):                                                   
REMARK 470   M RES CSSEQI  ATOMS                                                
REMARK 470     SER G   5    N                                                   
REMARK 470     LYS G  45    CG   CD   CE   NZ                                   
REMARK 470     ASP G  46    CG   OD1  OD2                                       
REMARK 470     LYS G  55    CG   CD   CE   NZ                                   
REMARK 470     LYS G  59    CG   CD   CE   NZ                                   
REMARK 470     SER G  63    OG                                                  
REMARK 470     GLU G 146    CG   CD   OE1  OE2                                  
REMARK 470     LYS G 181    CG   CD   CE   NZ                                   
REMARK 470     LYS G 186    CG   CD   CE   NZ                                   
REMARK 470     PHE G 187    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASP G 188    CG   OD1  OD2                                       
REMARK 470     GLU G 196    CG   CD   OE1  OE2                                  
REMARK 470     GLU G 223    CG   CD   OE1  OE2                                  
REMARK 470     LYS H  18    CG   CD   CE   NZ                                   
REMARK 470     VAL H  36    CG1  CG2                                            
REMARK 470     GLN H  52    CG   CD   OE1  NE2                                  
REMARK 470     LYS H  53    CG   CD   CE   NZ                                   
REMARK 470     SER H  54    OG                                                  
REMARK 470     ILE H  55    CG1  CG2  CD1                                       
REMARK 470     ARG H  60    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     TRP H 139    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP H 139    CZ3  CH2                                            
REMARK 470     ASN H 140    CG   OD1  ND2                                       
REMARK 470     GLU H 141    CG   CD   OE1  OE2                                  
REMARK 470     ARG H 143    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     MET H 163    CG   SD   CE                                        
REMARK 470     LYS H 176    CG   CD   CE   NZ                                   
REMARK 470     ARG H 177    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     TYR H 178    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LEU H 184    CG   CD1  CD2                                       
REMARK 470     LEU H 193    CG   CD1  CD2                                       
REMARK 470     LEU H 195    CG   CD1  CD2                                       
REMARK 470     LYS H 196    CG   CD   CE   NZ                                   
REMARK 470     PHE H 199    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLU H 200    CG   CD   OE1  OE2                                  
REMARK 470     GLN H 202    CG   CD   OE1  NE2                                  
REMARK 470     VAL H 226    CG1  CG2                                            
REMARK 470     LYS H 227    CG   CD   CE   NZ                                   
REMARK 470     LEU H 230    CG   CD1  CD2                                       
REMARK 470     ILE H 233    CG1  CG2  CD1                                       
REMARK 470     SER I  13    OG                                                  
REMARK 470     ILE I  37    CG1  CG2  CD1                                       
REMARK 470     ASN I  51    CG   OD1  ND2                                       
REMARK 470     ILE I  52    CG1  CG2  CD1                                       
REMARK 470     LYS I  54    CG   CD   CE   NZ                                   
REMARK 470     GLN I 177    CG   CD   OE1  NE2                                  
REMARK 470     MET I 184    CG   SD   CE                                        
REMARK 470     ILE I 194    CG1  CG2  CD1                                       
REMARK 470     MET I 201    CG   SD   CE                                        
REMARK 470     LYS I 205    CG   CD   CE   NZ                                   
REMARK 470     LYS I 210    CG   CD   CE   NZ                                   
REMARK 470     LYS I 222    CG   CD   CE   NZ                                   
REMARK 470     LYS I 229    CG   CD   CE   NZ                                   
REMARK 470     GLN I 230    CG   CD   OE1  NE2                                  
REMARK 470     LYS I 231    CG   CD   CE   NZ                                   
REMARK 470     GLU I 250    CG   CD   OE1  OE2                                  
REMARK 470     LYS I 251    CG   CD   CE   NZ                                   
REMARK 470     LYS J  27    CG   CD   CE   NZ                                   
REMARK 470     ILE J  40    CG1  CG2  CD1                                       
REMARK 470     VAL J  42    CG1  CG2                                            
REMARK 470     GLU J  46    CG   CD   OE1  OE2                                  
REMARK 470     LYS J  47    CG   CD   CE   NZ                                   
REMARK 470     LYS J  48    CG   CD   CE   NZ                                   
REMARK 470     SER J  49    OG                                                  
REMARK 470     VAL J  50    CG1  CG2                                            
REMARK 470     LEU J  53    CG   CD1  CD2                                       
REMARK 470     PHE J 136    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     PHE J 138    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     THR J 141    OG1  CG2                                            
REMARK 470     LYS J 157    CG   CD   CE   NZ                                   
REMARK 470     ARG J 163    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS J 166    CG   CD   CE   NZ                                   
REMARK 470     ARG J 169    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU J 170    CG   CD   OE1  OE2                                  
REMARK 470     LYS J 174    CG   CD   CE   NZ                                   
REMARK 470     ILE J 181    CG1  CG2  CD1                                       
REMARK 470     GLU J 182    CG   CD   OE1  OE2                                  
REMARK 470     THR J 183    OG1  CG2                                            
REMARK 470     ASP J 185    CG   OD1  OD2                                       
REMARK 470     THR J 187    OG1  CG2                                            
REMARK 470     LYS J 189    CG   CD   CE   NZ                                   
REMARK 470     ILE J 192    CG1  CG2  CD1                                       
REMARK 470     LYS J 193    CG   CD   CE   NZ                                   
REMARK 470     LEU J 195    CG   CD1  CD2                                       
REMARK 470     LEU J 196    CG   CD1  CD2                                       
REMARK 470     GLU J 197    CG   CD   OE1  OE2                                  
REMARK 470     VAL J 198    CG1  CG2                                            
REMARK 470     VAL J 199    CG1  CG2                                            
REMARK 470     LYS J 204    CG   CD   CE   NZ                                   
REMARK 470     GLU J 207    CG   CD   OE1  OE2                                  
REMARK 470     LEU J 208    CG   CD1  CD2                                       
REMARK 470     ARG J 212    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG J 213    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     SER J 216    OG                                                  
REMARK 470     LYS J 218    CG   CD   CE   NZ                                   
REMARK 470     GLU J 223    CG   CD   OE1  OE2                                  
REMARK 470     ILE J 225    CG1  CG2  CD1                                       
REMARK 470     GLU J 226    CG   CD   OE1  OE2                                  
REMARK 470     LYS J 227    CG   CD   CE   NZ                                   
REMARK 470     VAL J 229    CG1  CG2                                            
REMARK 470     ILE J 232    CG1  CG2  CD1                                       
REMARK 470     GLU J 233    CG   CD   OE1  OE2                                  
REMARK 470     LYS J 234    CG   CD   CE   NZ                                   
REMARK 470     GLU J 235    CG   CD   OE1  OE2                                  
REMARK 470     LYS J 236    CG   CD   CE   NZ                                   
REMARK 470     GLU J 237    CG   CD   OE1  OE2                                  
REMARK 470     ASN J 239    CG   OD1  ND2                                       
REMARK 470     GLU J 240    CG   CD   OE1  OE2                                  
REMARK 470     TYR K   8    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LYS K  86    CG   CD   CE   NZ                                   
REMARK 470     LYS K 187    CG   CD   CE   NZ                                   
REMARK 470     LYS K 192    CG   CD   CE   NZ                                   
REMARK 470     GLU K 208    CG   CD   OE1  OE2                                  
REMARK 470     LYS K 209    CG   CD   CE   NZ                                   
REMARK 470     LYS K 231    CG   CD   CE   NZ                                   
REMARK 470     LYS L 208    CG   CD   CE   NZ                                   
REMARK 470     LYS L 217    CG   CD   CE   NZ                                   
REMARK 470     ASP L 218    CG   OD1  OD2                                       
REMARK 470     GLU L 237    CG   CD   OE1  OE2                                  
REMARK 470     GLU L 238    CG   CD   OE1  OE2                                  
REMARK 470     GLN L 241    CG   CD   OE1  NE2                                  
REMARK 470     LYS M 109    CG   CD   CE   NZ                                   
REMARK 470     ASN M 143    CG   OD1  ND2                                       
REMARK 470     GLU M 203    CG   CD   OE1  OE2                                  
REMARK 470     LYS M 205    CG   CD   CE   NZ                                   
REMARK 470     LYS M 207    CG   CD   CE   NZ                                   
REMARK 470     ARG M 223    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS O   9    CG   CD   CE   NZ                                   
REMARK 470     LYS O 180    CG   CD   CE   NZ                                   
REMARK 470     LYS O 206    CG   CD   CE   NZ                                   
REMARK 470     GLU O 214    CG   CD   OE1  OE2                                  
REMARK 470     ARG P  48    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS Q  41    CG   CD   CE   NZ                                   
REMARK 470     ARG Q  95    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU Q 109    CG   CD   OE1  OE2                                  
REMARK 470     LYS Q 185    CG   CD   CE   NZ                                   
REMARK 470     LYS Q 198    CG   CD   CE   NZ                                   
REMARK 470     GLN Q 199    CG   CD   OE1  NE2                                  
REMARK 470     LYS R 106    CG   CD   CE   NZ                                   
REMARK 470     GLU R 150    CG   CD   OE1  OE2                                  
REMARK 470     ILE R 185    CG1  CG2  CD1                                       
REMARK 470     LYS S  45    CG   CD   CE   NZ                                   
REMARK 470     VAL S 161    CG1  CG2                                            
REMARK 470     LEU S 166    CG   CD1  CD2                                       
REMARK 470     LYS S 200    CG   CD   CE   NZ                                   
REMARK 470     ARG T  44    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS T 156    CG   CD   CE   NZ                                   
REMARK 470     LYS T 195    CG   CD   CE   NZ                                   
REMARK 470     LYS g  45    CG   CD   CE   NZ                                   
REMARK 470     ASP g  46    CG   OD1  OD2                                       
REMARK 470     LYS g  55    CG   CD   CE   NZ                                   
REMARK 470     LYS g  59    CG   CD   CE   NZ                                   
REMARK 470     SER g  63    OG                                                  
REMARK 470     GLU g 146    CG   CD   OE1  OE2                                  
REMARK 470     LYS g 181    CG   CD   CE   NZ                                   
REMARK 470     LYS g 186    CG   CD   CE   NZ                                   
REMARK 470     PHE g 187    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASP g 188    CG   OD1  OD2                                       
REMARK 470     GLU g 196    CG   CD   OE1  OE2                                  
REMARK 470     GLU g 223    CG   CD   OE1  OE2                                  
REMARK 470     LYS h  18    CG   CD   CE   NZ                                   
REMARK 470     VAL h  36    CG1  CG2                                            
REMARK 470     GLN h  52    CG   CD   OE1  NE2                                  
REMARK 470     LYS h  53    CG   CD   CE   NZ                                   
REMARK 470     SER h  54    OG                                                  
REMARK 470     ILE h  55    CG1  CG2  CD1                                       
REMARK 470     ARG h  60    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     TRP h 139    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP h 139    CZ3  CH2                                            
REMARK 470     ASN h 140    CG   OD1  ND2                                       
REMARK 470     GLU h 141    CG   CD   OE1  OE2                                  
REMARK 470     ARG h 143    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     MET h 163    CG   SD   CE                                        
REMARK 470     LYS h 176    CG   CD   CE   NZ                                   
REMARK 470     ARG h 177    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     TYR h 178    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LEU h 184    CG   CD1  CD2                                       
REMARK 470     LEU h 193    CG   CD1  CD2                                       
REMARK 470     LEU h 195    CG   CD1  CD2                                       
REMARK 470     LYS h 196    CG   CD   CE   NZ                                   
REMARK 470     PHE h 199    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLU h 200    CG   CD   OE1  OE2                                  
REMARK 470     GLN h 202    CG   CD   OE1  NE2                                  
REMARK 470     VAL h 226    CG1  CG2                                            
REMARK 470     LYS h 227    CG   CD   CE   NZ                                   
REMARK 470     LEU h 230    CG   CD1  CD2                                       
REMARK 470     ILE h 233    CG1  CG2  CD1                                       
REMARK 470     SER i  13    OG                                                  
REMARK 470     ILE i  37    CG1  CG2  CD1                                       
REMARK 470     ASN i  51    CG   OD1  ND2                                       
REMARK 470     ILE i  52    CG1  CG2  CD1                                       
REMARK 470     LYS i  54    CG   CD   CE   NZ                                   
REMARK 470     GLN i 177    CG   CD   OE1  NE2                                  
REMARK 470     MET i 184    CG   SD   CE                                        
REMARK 470     ILE i 194    CG1  CG2  CD1                                       
REMARK 470     MET i 201    CG   SD   CE                                        
REMARK 470     LYS i 205    CG   CD   CE   NZ                                   
REMARK 470     LYS i 210    CG   CD   CE   NZ                                   
REMARK 470     LYS i 222    CG   CD   CE   NZ                                   
REMARK 470     LYS i 229    CG   CD   CE   NZ                                   
REMARK 470     GLN i 230    CG   CD   OE1  NE2                                  
REMARK 470     LYS i 231    CG   CD   CE   NZ                                   
REMARK 470     GLU i 250    CG   CD   OE1  OE2                                  
REMARK 470     LYS i 251    CG   CD   CE   NZ                                   
REMARK 470     LYS j  27    CG   CD   CE   NZ                                   
REMARK 470     ILE j  40    CG1  CG2  CD1                                       
REMARK 470     VAL j  42    CG1  CG2                                            
REMARK 470     GLU j  46    CG   CD   OE1  OE2                                  
REMARK 470     LYS j  47    CG   CD   CE   NZ                                   
REMARK 470     LYS j  48    CG   CD   CE   NZ                                   
REMARK 470     SER j  49    OG                                                  
REMARK 470     VAL j  50    CG1  CG2                                            
REMARK 470     LEU j  53    CG   CD1  CD2                                       
REMARK 470     PHE j 136    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     PHE j 138    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     THR j 141    OG1  CG2                                            
REMARK 470     LYS j 157    CG   CD   CE   NZ                                   
REMARK 470     ARG j 163    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS j 166    CG   CD   CE   NZ                                   
REMARK 470     ARG j 169    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU j 170    CG   CD   OE1  OE2                                  
REMARK 470     LYS j 174    CG   CD   CE   NZ                                   
REMARK 470     ILE j 181    CG1  CG2  CD1                                       
REMARK 470     GLU j 182    CG   CD   OE1  OE2                                  
REMARK 470     THR j 183    OG1  CG2                                            
REMARK 470     ASP j 185    CG   OD1  OD2                                       
REMARK 470     THR j 187    OG1  CG2                                            
REMARK 470     LYS j 189    CG   CD   CE   NZ                                   
REMARK 470     ILE j 192    CG1  CG2  CD1                                       
REMARK 470     LYS j 193    CG   CD   CE   NZ                                   
REMARK 470     LEU j 195    CG   CD1  CD2                                       
REMARK 470     LEU j 196    CG   CD1  CD2                                       
REMARK 470     GLU j 197    CG   CD   OE1  OE2                                  
REMARK 470     VAL j 198    CG1  CG2                                            
REMARK 470     VAL j 199    CG1  CG2                                            
REMARK 470     LYS j 204    CG   CD   CE   NZ                                   
REMARK 470     GLU j 207    CG   CD   OE1  OE2                                  
REMARK 470     LEU j 208    CG   CD1  CD2                                       
REMARK 470     ARG j 212    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG j 213    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     SER j 216    OG                                                  
REMARK 470     LYS j 218    CG   CD   CE   NZ                                   
REMARK 470     GLU j 223    CG   CD   OE1  OE2                                  
REMARK 470     ILE j 225    CG1  CG2  CD1                                       
REMARK 470     GLU j 226    CG   CD   OE1  OE2                                  
REMARK 470     LYS j 227    CG   CD   CE   NZ                                   
REMARK 470     VAL j 229    CG1  CG2                                            
REMARK 470     ILE j 232    CG1  CG2  CD1                                       
REMARK 470     GLU j 233    CG   CD   OE1  OE2                                  
REMARK 470     LYS j 234    CG   CD   CE   NZ                                   
REMARK 470     GLU j 235    CG   CD   OE1  OE2                                  
REMARK 470     LYS j 236    CG   CD   CE   NZ                                   
REMARK 470     GLU j 237    CG   CD   OE1  OE2                                  
REMARK 470     ASN j 239    CG   OD1  ND2                                       
REMARK 470     GLU j 240    CG   CD   OE1  OE2                                  
REMARK 470     TYR k   8    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LYS k  86    CG   CD   CE   NZ                                   
REMARK 470     LYS k 187    CG   CD   CE   NZ                                   
REMARK 470     LYS k 192    CG   CD   CE   NZ                                   
REMARK 470     GLU k 208    CG   CD   OE1  OE2                                  
REMARK 470     LYS k 209    CG   CD   CE   NZ                                   
REMARK 470     LYS k 231    CG   CD   CE   NZ                                   
REMARK 470     LYS l 208    CG   CD   CE   NZ                                   
REMARK 470     LYS l 217    CG   CD   CE   NZ                                   
REMARK 470     ASP l 218    CG   OD1  OD2                                       
REMARK 470     GLU l 237    CG   CD   OE1  OE2                                  
REMARK 470     GLU l 238    CG   CD   OE1  OE2                                  
REMARK 470     GLN l 241    CG   CD   OE1  NE2                                  
REMARK 470     LYS m 109    CG   CD   CE   NZ                                   
REMARK 470     ASN m 143    CG   OD1  ND2                                       
REMARK 470     GLU m 203    CG   CD   OE1  OE2                                  
REMARK 470     LYS m 205    CG   CD   CE   NZ                                   
REMARK 470     LYS m 207    CG   CD   CE   NZ                                   
REMARK 470     ARG m 223    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS o   9    CG   CD   CE   NZ                                   
REMARK 470     LYS o 180    CG   CD   CE   NZ                                   
REMARK 470     LYS o 206    CG   CD   CE   NZ                                   
REMARK 470     GLU o 214    CG   CD   OE1  OE2                                  
REMARK 470     ARG p  48    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS q  41    CG   CD   CE   NZ                                   
REMARK 470     ARG q  95    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU q 109    CG   CD   OE1  OE2                                  
REMARK 470     LYS q 185    CG   CD   CE   NZ                                   
REMARK 470     LYS q 198    CG   CD   CE   NZ                                   
REMARK 470     GLN q 199    CG   CD   OE1  NE2                                  
REMARK 470     LYS r 106    CG   CD   CE   NZ                                   
REMARK 470     GLU r 150    CG   CD   OE1  OE2                                  
REMARK 470     ILE r 185    CG1  CG2  CD1                                       
REMARK 470     LYS s  45    CG   CD   CE   NZ                                   
REMARK 470     VAL s 161    CG1  CG2                                            
REMARK 470     LEU s 166    CG   CD1  CD2                                       
REMARK 470     LYS s 200    CG   CD   CE   NZ                                   
REMARK 470     ARG t  44    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS t 156    CG   CD   CE   NZ                                   
REMARK 470     LYS t 195    CG   CD   CE   NZ                                   
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT                     
REMARK 500                                                                      
REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT.                            
REMARK 500                                                                      
REMARK 500  ATM1  RES C  SSEQI   ATM2  RES C  SSEQI           DISTANCE          
REMARK 500   CG2  ILE U   105     NH2  ARG C    21              0.48            
REMARK 500   CA   LYS D   409     OE1  GLU D   411              0.52            
REMARK 500   CB   GLN U   149     CG   LYS C    15              0.59            
REMARK 500   CZ   ARG F   386     NE2  GLN L   166              0.62            
REMARK 500   SG   CYS U   141     CB   LEU C    11              0.65            
REMARK 500   N    LEU U   187     CG   LYS D    46              0.75            
REMARK 500   C    LYS U   148     NZ   LYS C    15              0.76            
REMARK 500   CG   LEU U   187     O    SER D    42              0.76            
REMARK 500   NH2  ARG F   386     NE2  GLN L   166              0.81            
REMARK 500   CD1  LEU U   183     OD1  ASP D    39              0.84            
REMARK 500   CG   GLU Y   170     NE2  GLN D   193              0.87            
REMARK 500   C    GLY U   152     CD2  TYR D    41              0.87            
REMARK 500   CD2  LEU U   187     O    SER D    42              0.87            
REMARK 500   SG   CYS U   141     CG   LEU C    11              0.92            
REMARK 500   CD2  LEU U   187     C    SER D    42              0.92            
REMARK 500   O    GLN K   224     CD2  HIS K   227              0.93            
REMARK 500   CA   ALA Y   133     ND1  HIS C   377              0.98            
REMARK 500   O    GLY U   594     CE2  PHE D    53              0.98            
REMARK 500   CG   GLN U   149     CB   LYS C    15              0.99            
REMARK 500   O    HIS D   414     OG   SER G     5              1.00            
REMARK 500   CB   CYS U   141     CD1  LEU C    11              1.01            
REMARK 500   N    ALA Y   133     ND1  HIS C   377              1.02            
REMARK 500   N    GLN U   149     NZ   LYS C    15              1.02            
REMARK 500   ND2  ASN U   596     C    GLU D    52              1.05            
REMARK 500   NH2  ARG F   386     CD   GLN L   166              1.07            
REMARK 500   O    GLY U   152     CD2  TYR D    41              1.08            
REMARK 500   CD1  TYR F   437     CD   GLN L    53              1.10            
REMARK 500   CD1  LEU U   183     CG   ASP D    39              1.11            
REMARK 500   CD   GLU Y   170     CD   GLN D   193              1.12            
REMARK 500   O    GLY U   152     CG   TYR D    41              1.14            
REMARK 500   CD1  TYR F   437     NE2  GLN L    53              1.15            
REMARK 500   OE1  GLU Y   170     CG   GLN D   193              1.15            
REMARK 500   ND1  HIS W   453     CD1  ILE Z   222              1.17            
REMARK 500   CA   MET V   192     O    GLN V   193              1.21            
REMARK 500   CG   GLU U   156     CE1  TYR D    41              1.22            
REMARK 500   CB   GLN U   149     CB   LYS C    15              1.24            
REMARK 500   N    LEU Y   134     CG1  VAL C   376              1.26            
REMARK 500   ND2  ASN U   596     N    PHE D    53              1.28            
REMARK 500   N    LYS D   409     OE1  GLU D   411              1.31            
REMARK 500   C    LYS D   409     CG   GLU D   411              1.32            
REMARK 500   O    GLY U   594     CZ   PHE D    53              1.34            
REMARK 500   CD1  TYR F   437     OE1  GLN L    53              1.35            
REMARK 500   CA   GLN U   149     CG   LYS C    15              1.38            
REMARK 500   CB   LYS D   409     CD   GLU D   411              1.39            
REMARK 500   O    TYR D   417     O    PRO G    18              1.39            
REMARK 500   CB   LYS D   409     OE1  GLU D   411              1.39            
REMARK 500   N    GLN U   149     CE   LYS C    15              1.40            
REMARK 500   CB   LEU U   187     N    LYS D    46              1.40            
REMARK 500   CA   LEU U   187     CG   LYS D    46              1.41            
REMARK 500   OD1  ASN U   596     CA   PHE D    53              1.41            
REMARK 500                                                                      
REMARK 500 THIS ENTRY HAS     289 CLOSE CONTACTS                                
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES                                       
REMARK 500                                                                      
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES              
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE               
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                 
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)              
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999                        
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996                     
REMARK 500                                                                      
REMARK 500  M RES CSSEQI ATM1   ATM2   ATM3                                     
REMARK 500    PRO Y 359   C   -  N   -  CD  ANGL. DEV. = -17.1 DEGREES          
REMARK 500    PRO Z 221   C   -  N   -  CD  ANGL. DEV. = -26.3 DEGREES          
REMARK 500    LEU i  35   CA  -  CB  -  CG  ANGL. DEV. =  15.7 DEGREES          
REMARK 500    PRO f 193   C   -  N   -  CA  ANGL. DEV. =  -9.7 DEGREES          
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: TORSION ANGLES                                             
REMARK 500                                                                      
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:            
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)                    
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-           
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400            
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        PSI       PHI                                   
REMARK 500    ALA U  29      -64.25    -98.00                                   
REMARK 500    PHE U  74      -66.77   -106.96                                   
REMARK 500    SER U  94     -138.93     49.89                                   
REMARK 500    GLU U 122       -0.53     65.12                                   
REMARK 500    ASN U 171     -143.09     55.99                                   
REMARK 500    GLN U 189      -64.96    -92.63                                   
REMARK 500    ASP U 224       66.25     38.58                                   
REMARK 500    LEU U 242      -63.13   -129.17                                   
REMARK 500    VAL U 364      -13.05     67.06                                   
REMARK 500    THR U 381       -3.77     65.87                                   
REMARK 500    LEU U 390      -63.03   -127.87                                   
REMARK 500    ASN U 398     -124.26     60.60                                   
REMARK 500    PRO U 428       74.73    -67.84                                   
REMARK 500    ASN U 452     -118.10     60.77                                   
REMARK 500    ALA U 468     -138.95     57.92                                   
REMARK 500    GLN U 491      -62.69    -92.55                                   
REMARK 500    ASP U 504       72.70     59.70                                   
REMARK 500    ALA U 506      -65.25   -101.74                                   
REMARK 500    MET U 560     -120.91     57.88                                   
REMARK 500    VAL U 607      -65.05   -108.25                                   
REMARK 500    GLN U 697       -5.43     64.67                                   
REMARK 500    HIS U 742       -4.07     67.27                                   
REMARK 500    ASP U 794     -138.17     45.26                                   
REMARK 500    ALA U 837      -70.11    -58.31                                   
REMARK 500    GLU U 843       66.39     60.90                                   
REMARK 500    SER U 907      -66.14   -128.21                                   
REMARK 500    ASP V  34      -64.39   -105.93                                   
REMARK 500    THR V  55       63.78     32.13                                   
REMARK 500    ALA V  56       45.64   -163.86                                   
REMARK 500    ALA V  57       52.99   -148.74                                   
REMARK 500    ALA V  58     -167.80    116.16                                   
REMARK 500    ALA V  59       70.16     39.45                                   
REMARK 500    ILE V  75      -64.40   -103.58                                   
REMARK 500    HIS V  78     -142.00     59.59                                   
REMARK 500    VAL V  79      -67.68   -134.75                                   
REMARK 500    GLN V  81     -138.27     92.98                                   
REMARK 500    LEU V  82      -61.61   -135.08                                   
REMARK 500    GLU V  83      -15.32     65.30                                   
REMARK 500    VAL V  86       71.75     44.47                                   
REMARK 500    ARG V  96       72.84     44.41                                   
REMARK 500    PHE V 120      -64.43   -107.32                                   
REMARK 500    THR V 127      -67.92   -109.65                                   
REMARK 500    ARG V 128     -116.56     55.05                                   
REMARK 500    GLU V 142       72.21     56.62                                   
REMARK 500    LEU V 170      -16.64     67.13                                   
REMARK 500    LEU V 191      -76.23   -121.11                                   
REMARK 500    GLN V 193      146.99      9.88                                   
REMARK 500    ILE V 195      -78.82   -118.83                                   
REMARK 500    THR V 197       70.52    -55.69                                   
REMARK 500    GLN V 198       -9.31    -55.21                                   
REMARK 500                                                                      
REMARK 500 THIS ENTRY HAS     542 RAMACHANDRAN OUTLIERS.                        
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: NON-CIS, NON-TRANS                                         
REMARK 500                                                                      
REMARK 500 THE FOLLOWING PEPTIDE BONDS DEVIATE SIGNIFICANTLY FROM BOTH          
REMARK 500 CIS AND TRANS CONFORMATION.  CIS BONDS, IF ANY, ARE LISTED           
REMARK 500 ON CISPEP RECORDS.  TRANS IS DEFINED AS 180 +/- 30 AND               
REMARK 500 CIS IS DEFINED AS 0 +/- 30 DEGREES.                                  
REMARK 500                                 MODEL     OMEGA                      
REMARK 500 SER U  432     PRO U  433                  147.02                    
REMARK 500 PRO U  433     GLY U  434                 -138.35                    
REMARK 500 SER U  435     ALA U  436                 -144.33                    
REMARK 500 LYS V   54     THR V   55                   46.28                    
REMARK 500 ALA V   57     ALA V   58                  -99.49                    
REMARK 500 LYS V   80     GLN V   81                  -62.42                    
REMARK 500 HIS V  319     THR V  320                  -36.45                    
REMARK 500 TRP Y   63     GLN Y   64                 -105.06                    
REMARK 500 THR Y  356     ASN Y  357                  -72.14                    
REMARK 500 PRO Z  221     ILE Z  222                  -61.61                    
REMARK 500 GLU d    3     GLN d    4                  -34.72                    
REMARK 500 ILE A  157     ASP A  158                   37.86                    
REMARK 500 VAL B  133     SER B  134                  149.42                    
REMARK 500 PRO B  264     LYS B  265                 -146.72                    
REMARK 500 HIS C  171     PRO C  172                 -139.23                    
REMARK 500 ILE D  151     MET D  152                  -77.27                    
REMARK 500 PRO E  292     GLY E  293                 -148.04                    
REMARK 500 PRO F   87     TYR F   88                 -147.14                    
REMARK 500 LYS F  294     ARG F  295                 -146.44                    
REMARK 500 TYR G  160     CYS G  161                 -148.88                    
REMARK 500 ALA H   40     ALA H   41                  149.56                    
REMARK 500 ALA H  231     ALA H  232                   35.83                    
REMARK 500 HIS J   15     LEU J   16                  149.01                    
REMARK 500 VAL J  199     GLN J  200                 -134.54                    
REMARK 500 ARG K   10     GLY K   11                  137.05                    
REMARK 500 TYR L  137     ASP L  138                  144.07                    
REMARK 500 ASP L  204     LEU L  205                   37.09                    
REMARK 500 LYS M   56     LEU M   57                 -139.70                    
REMARK 500 ARG O  187     PRO O  188                 -119.53                    
REMARK 500 ASN Q  101     LEU Q  102                 -147.36                    
REMARK 500 THR Q  139     LEU Q  140                 -149.66                    
REMARK 500 VAL j  199     GLN j  200                 -129.40                    
REMARK 500 ARG k   10     GLY k   11                  138.58                    
REMARK 500 HIS k  227     MET k  228                   62.94                    
REMARK 500 GLU k  232     GLU k  233                  145.72                    
REMARK 500 ASP l  204     LEU l  205                   74.38                    
REMARK 500 GLY p  101     PRO p  102                 -147.09                    
REMARK 500 LEU q  102     LEU q  103                 -144.00                    
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: MAIN CHAIN PLANARITY                                       
REMARK 500                                                                      
REMARK 500 THE FOLLOWING RESIDUES HAVE A PSEUDO PLANARITY                       
REMARK 500 TORSION ANGLE, C(I) - CA(I) - N(I+1) - O(I), GREATER                 
REMARK 500 10.0 DEGREES. (M=MODEL NUMBER; RES=RESIDUE NAME;                     
REMARK 500 C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;                            
REMARK 500 I=INSERTION CODE).                                                   
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        ANGLE                                           
REMARK 500    GLU c 242         11.72                                           
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 800                                                                      
REMARK 800 SITE                                                                 
REMARK 800 SITE_IDENTIFIER: AC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue ZN c 401                  
REMARK 900                                                                      
REMARK 900 RELATED ENTRIES                                                      
REMARK 900 RELATED ID: EMD-8667   RELATED DB: EMDB                              
REMARK 900 NUCLEOTIDE-DRIVEN TRIPLE-STATE REMODELING OF THE AAA-ATPASE CHANNEL  
REMARK 900 IN THE ACTIVATED HUMAN 26S PROTEASOME                                
REMARK 900 RELATED ID: EMD-8662   RELATED DB: EMDB                              
REMARK 900 RELATED ID: EMD-8663   RELATED DB: EMDB                              
REMARK 900 RELATED ID: EMD-8664   RELATED DB: EMDB                              
REMARK 900 RELATED ID: EMD-8665   RELATED DB: EMDB                              
REMARK 900 RELATED ID: EMD-8666   RELATED DB: EMDB                              
REMARK 900 RELATED ID: EMD-8668   RELATED DB: EMDB                              
REMARK 900 RELATED ID: 5VFS   RELATED DB: PDB                                   
REMARK 900 RELATED ID: 5VFO   RELATED DB: PDB                                   
REMARK 900 RELATED ID: 5VFP   RELATED DB: PDB                                   
REMARK 900 RELATED ID: 5VFQ   RELATED DB: PDB                                   
REMARK 900 RELATED ID: 5VFR   RELATED DB: PDB                                   
REMARK 900 RELATED ID: 5VFU   RELATED DB: PDB                                   
DBREF  5VFT U    7   917  UNP    Q99460   PSMD1_HUMAN      7    917             
DBREF  5VFT V   18   497  UNP    O43242   PSMD3_HUMAN     18    497             
DBREF  5VFT W    1   456  UNP    O00232   PSD12_HUMAN      1    456             
DBREF  5VFT X   43   422  UNP    O00231   PSD11_HUMAN     43    422             
DBREF  5VFT Y   12   389  UNP    Q15008   PSMD6_HUMAN     12    389             
DBREF  5VFT Z    5   290  UNP    P51665   PSMD7_HUMAN      5    290             
DBREF1 5VFT a    4   376  UNP                  A0A024R201_HUMAN                 
DBREF2 5VFT a     A0A024R201                          4         376             
DBREF  5VFT b    1   191  UNP    P55036   PSMD4_HUMAN      1    191             
DBREF  5VFT c   24   310  UNP    O00487   PSDE_HUMAN      24    310             
DBREF  5VFT d    1   257  UNP    P48556   PSMD8_HUMAN     94    350             
DBREF  5VFT e    1    70  PDB    5VFT     5VFT             1     70             
DBREF  5VFT A   73   433  UNP    P35998   PRS7_HUMAN      73    433             
DBREF  5VFT B   93   433  UNP    P62191   PRS4_HUMAN      93    433             
DBREF  5VFT C   11   394  UNP    P62195   PRS8_HUMAN      11    394             
DBREF  5VFT D   39   418  UNP    P43686   PRS6B_HUMAN     39    418             
DBREF  5VFT E   37   389  UNP    P62333   PRS10_HUMAN     37    389             
DBREF  5VFT F   63   439  UNP    P17980   PRS6A_HUMAN     63    439             
DBREF  5VFT G    5   244  UNP    P60900   PSA6_HUMAN       5    244             
DBREF  5VFT H    3   234  UNP    P25787   PSA2_HUMAN       3    234             
DBREF  5VFT I    2   251  UNP    P25789   PSA4_HUMAN       2    251             
DBREF  5VFT J    2   244  UNP    O14818   PSA7_HUMAN       2    244             
DBREF  5VFT K    8   241  UNP    P28066   PSA5_HUMAN       8    241             
DBREF  5VFT L    4   241  UNP    P25786   PSA1_HUMAN       4    241             
DBREF  5VFT M    1   245  UNP    P25788   PSA3_HUMAN       2    246             
DBREF  5VFT N    1   191  UNP    P28072   PSB6_HUMAN      35    225             
DBREF  5VFT O    1   220  UNP    Q99436   PSB7_HUMAN      44    263             
DBREF  5VFT P    2   205  UNP    P49720   PSB3_HUMAN       2    205             
DBREF  5VFT Q    1   199  UNP    P49721   PSB2_HUMAN       1    199             
DBREF  5VFT R    1   201  UNP    P28074   PSB5_HUMAN      60    260             
DBREF  5VFT S    1   213  UNP    P20618   PSB1_HUMAN      29    241             
DBREF  5VFT T    1   215  UNP    P28070   PSB4_HUMAN      46    260             
DBREF  5VFT g    5   244  UNP    P60900   PSA6_HUMAN       5    244             
DBREF  5VFT h    3   234  UNP    P25787   PSA2_HUMAN       3    234             
DBREF  5VFT i    2   251  UNP    P25789   PSA4_HUMAN       2    251             
DBREF  5VFT j    2   244  UNP    O14818   PSA7_HUMAN       2    244             
DBREF  5VFT k    8   241  UNP    P28066   PSA5_HUMAN       8    241             
DBREF  5VFT l    4   241  UNP    P25786   PSA1_HUMAN       4    241             
DBREF  5VFT m    1   245  UNP    P25788   PSA3_HUMAN       2    246             
DBREF  5VFT n    1   191  UNP    P28072   PSB6_HUMAN      35    225             
DBREF  5VFT o    1   220  UNP    Q99436   PSB7_HUMAN      44    263             
DBREF  5VFT p    2   205  UNP    P49720   PSB3_HUMAN       2    205             
DBREF  5VFT q    1   199  UNP    P49721   PSB2_HUMAN       1    199             
DBREF  5VFT r    1   201  UNP    P28074   PSB5_HUMAN      60    260             
DBREF  5VFT s    1   213  UNP    P20618   PSB1_HUMAN      29    241             
DBREF  5VFT t    1   215  UNP    P28070   PSB4_HUMAN      46    260             
DBREF  5VFT f    1   694  UNP    Q13200   PSMD2_HUMAN      1    694             
DBREF  5VFT f  695   908  PDB    5VFT     5VFT           695    908             
SEQRES   1 U  911  GLY ILE ILE SER LEU LEU ASP GLU ASP GLU PRO GLN LEU          
SEQRES   2 U  911  LYS GLU PHE ALA LEU HIS LYS LEU ASN ALA VAL VAL ASN          
SEQRES   3 U  911  ASP PHE TRP ALA GLU ILE SER GLU SER VAL ASP LYS ILE          
SEQRES   4 U  911  GLU VAL LEU TYR GLU ASP GLU GLY PHE ARG SER ARG GLN          
SEQRES   5 U  911  PHE ALA ALA LEU VAL ALA SER LYS VAL PHE TYR HIS LEU          
SEQRES   6 U  911  GLY ALA PHE GLU GLU SER LEU ASN TYR ALA LEU GLY ALA          
SEQRES   7 U  911  GLY ASP LEU PHE ASN VAL ASN ASP ASN SER GLU TYR VAL          
SEQRES   8 U  911  GLU THR ILE ILE ALA LYS CYS ILE ASP HIS TYR THR LYS          
SEQRES   9 U  911  GLN CYS VAL GLU ASN ALA ASP LEU PRO GLU GLY GLU LYS          
SEQRES  10 U  911  LYS PRO ILE ASP GLN ARG LEU GLU GLY ILE VAL ASN LYS          
SEQRES  11 U  911  MET PHE GLN ARG CYS LEU ASP ASP HIS LYS TYR LYS GLN          
SEQRES  12 U  911  ALA ILE GLY ILE ALA LEU GLU THR ARG ARG LEU ASP VAL          
SEQRES  13 U  911  PHE GLU LYS THR ILE LEU GLU SER ASN ASP VAL PRO GLY          
SEQRES  14 U  911  MET LEU ALA TYR SER LEU LYS LEU CYS MET SER LEU MET          
SEQRES  15 U  911  GLN ASN LYS GLN PHE ARG ASN LYS VAL LEU ARG VAL LEU          
SEQRES  16 U  911  VAL LYS ILE TYR MET ASN LEU GLU LYS PRO ASP PHE ILE          
SEQRES  17 U  911  ASN VAL CYS GLN CYS LEU ILE PHE LEU ASP ASP PRO GLN          
SEQRES  18 U  911  ALA VAL SER ASP ILE LEU GLU LYS LEU VAL LYS GLU ASP          
SEQRES  19 U  911  ASN LEU LEU MET ALA TYR GLN ILE CYS PHE ASP LEU TYR          
SEQRES  20 U  911  GLU SER ALA SER GLN GLN PHE LEU SER SER VAL ILE GLN          
SEQRES  21 U  911  ASN LEU ARG THR VAL GLY THR PRO ILE ALA SER VAL PRO          
SEQRES  22 U  911  GLY SER THR ASN THR GLY THR VAL PRO GLY SER GLU LYS          
SEQRES  23 U  911  ASP SER ASP SER MET GLU THR GLU GLU LYS THR SER SER          
SEQRES  24 U  911  ALA PHE VAL GLY LYS THR PRO GLU ALA SER PRO GLU PRO          
SEQRES  25 U  911  LYS ASP GLN THR LEU LYS MET ILE LYS ILE LEU SER GLY          
SEQRES  26 U  911  GLU MET ALA ILE GLU LEU HIS LEU GLN PHE LEU ILE ARG          
SEQRES  27 U  911  ASN ASN ASN THR ASP LEU MET ILE LEU LYS ASN THR LYS          
SEQRES  28 U  911  ASP ALA VAL ARG ASN SER VAL CYS HIS THR ALA THR VAL          
SEQRES  29 U  911  ILE ALA ASN SER PHE MET HIS CYS GLY THR THR SER ASP          
SEQRES  30 U  911  GLN PHE LEU ARG ASP ASN LEU GLU TRP LEU ALA ARG ALA          
SEQRES  31 U  911  THR ASN TRP ALA LYS PHE THR ALA THR ALA SER LEU GLY          
SEQRES  32 U  911  VAL ILE HIS LYS GLY HIS GLU LYS GLU ALA LEU GLN LEU          
SEQRES  33 U  911  MET ALA THR TYR LEU PRO LYS ASP THR SER PRO GLY SER          
SEQRES  34 U  911  ALA TYR GLN GLU GLY GLY GLY LEU TYR ALA LEU GLY LEU          
SEQRES  35 U  911  ILE HIS ALA ASN HIS GLY GLY ASP ILE ILE ASP TYR LEU          
SEQRES  36 U  911  LEU ASN GLN LEU LYS ASN ALA SER ASN ASP ILE VAL ARG          
SEQRES  37 U  911  HIS GLY GLY SER LEU GLY LEU GLY LEU ALA ALA MET GLY          
SEQRES  38 U  911  THR ALA ARG GLN ASP VAL TYR ASP LEU LEU LYS THR ASN          
SEQRES  39 U  911  LEU TYR GLN ASP ASP ALA VAL THR GLY GLU ALA ALA GLY          
SEQRES  40 U  911  LEU ALA LEU GLY LEU VAL MET LEU GLY SER LYS ASN ALA          
SEQRES  41 U  911  GLN ALA ILE GLU ASP MET VAL GLY TYR ALA GLN GLU THR          
SEQRES  42 U  911  GLN HIS GLU LYS ILE LEU ARG GLY LEU ALA VAL GLY ILE          
SEQRES  43 U  911  ALA LEU VAL MET TYR GLY ARG MET GLU GLU ALA ASP ALA          
SEQRES  44 U  911  LEU ILE GLU SER LEU CYS ARG ASP LYS ASP PRO ILE LEU          
SEQRES  45 U  911  ARG ARG SER GLY MET TYR THR VAL ALA MET ALA TYR CYS          
SEQRES  46 U  911  GLY SER GLY ASN ASN LYS ALA ILE ARG ARG LEU LEU HIS          
SEQRES  47 U  911  VAL ALA VAL SER ASP VAL ASN ASP ASP VAL ARG ARG ALA          
SEQRES  48 U  911  ALA VAL GLU SER LEU GLY PHE ILE LEU PHE ARG THR PRO          
SEQRES  49 U  911  GLU GLN CYS PRO SER VAL VAL SER LEU LEU SER GLU SER          
SEQRES  50 U  911  TYR ASN PRO HIS VAL ARG TYR GLY ALA ALA MET ALA LEU          
SEQRES  51 U  911  GLY ILE CYS CYS ALA GLY THR GLY ASN LYS GLU ALA ILE          
SEQRES  52 U  911  ASN LEU LEU GLU PRO MET THR ASN ASP PRO VAL ASN TYR          
SEQRES  53 U  911  VAL ARG GLN GLY ALA LEU ILE ALA SER ALA LEU ILE MET          
SEQRES  54 U  911  ILE GLN GLN THR GLU ILE THR CYS PRO LYS VAL ASN GLN          
SEQRES  55 U  911  PHE ARG GLN LEU TYR SER LYS VAL ILE ASN ASP LYS HIS          
SEQRES  56 U  911  ASP ASP VAL MET ALA LYS PHE GLY ALA ILE LEU ALA GLN          
SEQRES  57 U  911  GLY ILE LEU ASP ALA GLY GLY HIS ASN VAL THR ILE SER          
SEQRES  58 U  911  LEU GLN SER ARG THR GLY HIS THR HIS MET PRO SER VAL          
SEQRES  59 U  911  VAL GLY VAL LEU VAL PHE THR GLN PHE TRP PHE TRP PHE          
SEQRES  60 U  911  PRO LEU SER HIS PHE LEU SER LEU ALA TYR THR PRO THR          
SEQRES  61 U  911  CYS VAL ILE GLY LEU ASN LYS ASP LEU LYS MET PRO LYS          
SEQRES  62 U  911  VAL GLN TYR LYS SER ASN CYS LYS PRO SER THR PHE ALA          
SEQRES  63 U  911  TYR PRO ALA PRO LEU GLU VAL PRO LYS GLU LYS GLU LYS          
SEQRES  64 U  911  GLU LYS VAL SER THR ALA VAL LEU SER ILE THR ALA LYS          
SEQRES  65 U  911  ALA LYS LYS LYS GLU LYS GLU LYS GLU LYS LYS GLU GLU          
SEQRES  66 U  911  GLU LYS MET GLU VAL ASP GLU ALA GLU LYS LYS GLU GLU          
SEQRES  67 U  911  LYS GLU LYS LYS LYS GLU PRO GLU PRO ASN PHE GLN LEU          
SEQRES  68 U  911  LEU ASP ASN PRO ALA ARG VAL MET PRO ALA GLN LEU LYS          
SEQRES  69 U  911  VAL LEU THR MET PRO GLU THR CYS ARG TYR GLN PRO PHE          
SEQRES  70 U  911  LYS PRO LEU SER ILE GLY GLY ILE ILE ILE LEU LYS ASP          
SEQRES  71 U  911  THR                                                          
SEQRES   1 V  480  PRO PRO GLY GLY GLY GLU GLN GLU PRO PRO PRO PRO PRO          
SEQRES   2 V  480  ALA PRO GLN ASP VAL GLU MET LYS GLU GLU ALA ALA THR          
SEQRES   3 V  480  GLY GLY GLY SER THR GLY GLU ALA ASP GLY LYS THR ALA          
SEQRES   4 V  480  ALA ALA ALA ALA GLU HIS SER GLN ARG GLU LEU ASP THR          
SEQRES   5 V  480  VAL THR LEU GLU ASP ILE LYS GLU HIS VAL LYS GLN LEU          
SEQRES   6 V  480  GLU LYS ALA VAL SER GLY LYS GLU PRO ARG PHE VAL LEU          
SEQRES   7 V  480  ARG ALA LEU ARG MET LEU PRO SER THR SER ARG ARG LEU          
SEQRES   8 V  480  ASN HIS TYR VAL LEU TYR LYS ALA VAL GLN GLY PHE PHE          
SEQRES   9 V  480  THR SER ASN ASN ALA THR ARG ASP PHE LEU LEU PRO PHE          
SEQRES  10 V  480  LEU GLU GLU PRO MET ASP THR GLU ALA ASP LEU GLN PHE          
SEQRES  11 V  480  ARG PRO ARG THR GLY LYS ALA ALA SER THR PRO LEU LEU          
SEQRES  12 V  480  PRO GLU VAL GLU ALA TYR LEU GLN LEU LEU VAL VAL ILE          
SEQRES  13 V  480  PHE MET MET ASN SER LYS ARG TYR LYS GLU ALA GLN LYS          
SEQRES  14 V  480  ILE SER ASP ASP LEU MET GLN LYS ILE SER THR GLN ASN          
SEQRES  15 V  480  ARG ARG ALA LEU ASP LEU VAL ALA ALA LYS CYS TYR TYR          
SEQRES  16 V  480  TYR HIS ALA ARG VAL TYR GLU PHE LEU ASP LYS LEU ASP          
SEQRES  17 V  480  VAL VAL ARG SER PHE LEU HIS ALA ARG LEU ARG THR ALA          
SEQRES  18 V  480  THR LEU ARG HIS ASP ALA ASP GLY GLN ALA THR LEU LEU          
SEQRES  19 V  480  ASN LEU LEU LEU ARG ASN TYR LEU HIS TYR SER LEU TYR          
SEQRES  20 V  480  ASP GLN ALA GLU LYS LEU VAL SER LYS SER VAL PHE PRO          
SEQRES  21 V  480  GLU GLN ALA ASN ASN ASN GLU TRP ALA ARG TYR LEU TYR          
SEQRES  22 V  480  TYR THR GLY ARG ILE LYS ALA ILE GLN LEU GLU TYR SER          
SEQRES  23 V  480  GLU ALA ARG ARG THR MET THR ASN ALA LEU ARG LYS ALA          
SEQRES  24 V  480  PRO GLN HIS THR ALA VAL GLY PHE LYS GLN THR VAL HIS          
SEQRES  25 V  480  LYS LEU LEU ILE VAL VAL GLU LEU LEU LEU GLY GLU ILE          
SEQRES  26 V  480  PRO ASP ARG LEU GLN PHE ARG GLN PRO SER LEU LYS ARG          
SEQRES  27 V  480  SER LEU MET PRO TYR PHE LEU LEU THR GLN ALA VAL ARG          
SEQRES  28 V  480  THR GLY ASN LEU ALA LYS PHE ASN GLN VAL LEU ASP GLN          
SEQRES  29 V  480  PHE GLY GLU LYS PHE GLN ALA ASP GLY THR TYR THR LEU          
SEQRES  30 V  480  ILE ILE ARG LEU ARG HIS ASN VAL ILE LYS THR GLY VAL          
SEQRES  31 V  480  ARG MET ILE SER LEU SER TYR SER ARG ILE SER LEU ALA          
SEQRES  32 V  480  ASP ILE ALA GLN LYS LEU GLN LEU ASP SER PRO GLU ASP          
SEQRES  33 V  480  ALA GLU PHE ILE VAL ALA LYS ALA ILE ARG ASP GLY VAL          
SEQRES  34 V  480  ILE GLU ALA SER ILE ASN HIS GLU LYS GLY TYR VAL GLN          
SEQRES  35 V  480  SER LYS GLU MET ILE ASP ILE TYR SER THR ARG GLU PRO          
SEQRES  36 V  480  GLN LEU ALA PHE HIS GLN ARG ILE SER PHE CYS LEU ASP          
SEQRES  37 V  480  ILE HIS ASN MET SER VAL LYS ALA MET ARG PHE PRO              
SEQRES   1 W  456  MET ALA ASP GLY GLY SER GLU ARG ALA ASP GLY ARG ILE          
SEQRES   2 W  456  VAL LYS MET GLU VAL ASP TYR SER ALA THR VAL ASP GLN          
SEQRES   3 W  456  ARG LEU PRO GLU CYS ALA LYS LEU ALA LYS GLU GLY ARG          
SEQRES   4 W  456  LEU GLN GLU VAL ILE GLU THR LEU LEU SER LEU GLU LYS          
SEQRES   5 W  456  GLN THR ARG THR ALA SER ASP MET VAL SER THR SER ARG          
SEQRES   6 W  456  ILE LEU VAL ALA VAL VAL LYS MET CYS TYR GLU ALA LYS          
SEQRES   7 W  456  GLU TRP ASP LEU LEU ASN GLU ASN ILE MET LEU LEU SER          
SEQRES   8 W  456  LYS ARG ARG SER GLN LEU LYS GLN ALA VAL ALA LYS MET          
SEQRES   9 W  456  VAL GLN GLN CYS CYS THR TYR VAL GLU GLU ILE THR ASP          
SEQRES  10 W  456  LEU PRO ILE LYS LEU ARG LEU ILE ASP THR LEU ARG MET          
SEQRES  11 W  456  VAL THR GLU GLY LYS ILE TYR VAL GLU ILE GLU ARG ALA          
SEQRES  12 W  456  ARG LEU THR LYS THR LEU ALA THR ILE LYS GLU GLN ASN          
SEQRES  13 W  456  GLY ASP VAL LYS GLU ALA ALA SER ILE LEU GLN GLU LEU          
SEQRES  14 W  456  GLN VAL GLU THR TYR GLY SER MET GLU LYS LYS GLU ARG          
SEQRES  15 W  456  VAL GLU PHE ILE LEU GLU GLN MET ARG LEU CYS LEU ALA          
SEQRES  16 W  456  VAL LYS ASP TYR ILE ARG THR GLN ILE ILE SER LYS LYS          
SEQRES  17 W  456  ILE ASN THR LYS PHE PHE GLN GLU GLU ASN THR GLU LYS          
SEQRES  18 W  456  LEU LYS LEU LYS TYR TYR ASN LEU MET ILE GLN LEU ASP          
SEQRES  19 W  456  GLN HIS GLU GLY SER TYR LEU SER ILE CYS LYS HIS TYR          
SEQRES  20 W  456  ARG ALA ILE TYR ASP THR PRO CYS ILE GLN ALA GLU SER          
SEQRES  21 W  456  GLU LYS TRP GLN GLN ALA LEU LYS SER VAL VAL LEU TYR          
SEQRES  22 W  456  VAL ILE LEU ALA PRO PHE ASP ASN GLU GLN SER ASP LEU          
SEQRES  23 W  456  VAL HIS ARG ILE SER GLY ASP LYS LYS LEU GLU GLU ILE          
SEQRES  24 W  456  PRO LYS TYR LYS ASP LEU LEU LYS LEU PHE THR THR MET          
SEQRES  25 W  456  GLU LEU MET ARG TRP SER THR LEU VAL GLU ASP TYR GLY          
SEQRES  26 W  456  MET GLU LEU ARG LYS GLY SER LEU GLU SER PRO ALA THR          
SEQRES  27 W  456  ASP VAL PHE GLY SER THR GLU GLU GLY GLU LYS ARG TRP          
SEQRES  28 W  456  LYS ASP LEU LYS ASN ARG VAL VAL GLU HIS ASN ILE ARG          
SEQRES  29 W  456  ILE MET ALA LYS TYR TYR THR ARG ILE THR MET LYS ARG          
SEQRES  30 W  456  MET ALA GLN LEU LEU ASP LEU SER VAL ASP GLU SER GLU          
SEQRES  31 W  456  ALA PHE LEU SER ASN LEU VAL VAL ASN LYS THR ILE PHE          
SEQRES  32 W  456  ALA LYS VAL ASP ARG LEU ALA GLY ILE ILE ASN PHE GLN          
SEQRES  33 W  456  ARG PRO LYS ASP PRO ASN ASN LEU LEU ASN ASP TRP SER          
SEQRES  34 W  456  GLN LYS LEU ASN SER LEU MET SER LEU VAL ASN LYS THR          
SEQRES  35 W  456  THR HIS LEU ILE ALA LYS GLU GLU MET ILE HIS ASN LEU          
SEQRES  36 W  456  GLN                                                          
SEQRES   1 X  380  VAL GLN VAL LYS GLU GLN SER ILE LEU GLU LEU GLY SER          
SEQRES   2 X  380  LEU LEU ALA LYS THR GLY GLN ALA ALA GLU LEU GLY GLY          
SEQRES   3 X  380  LEU LEU LYS TYR VAL ARG PRO PHE LEU ASN SER ILE SER          
SEQRES   4 X  380  LYS ALA LYS ALA ALA ARG LEU VAL ARG SER LEU LEU ASP          
SEQRES   5 X  380  LEU PHE LEU ASP MET GLU ALA ALA THR GLY GLN GLU VAL          
SEQRES   6 X  380  GLU LEU CYS LEU GLU CYS ILE GLU TRP ALA LYS SER GLU          
SEQRES   7 X  380  LYS ARG THR PHE LEU ARG GLN ALA LEU GLU ALA ARG LEU          
SEQRES   8 X  380  VAL SER LEU TYR PHE ASP THR LYS ARG TYR GLN GLU ALA          
SEQRES   9 X  380  LEU HIS LEU GLY SER GLN LEU LEU ARG GLU LEU LYS LYS          
SEQRES  10 X  380  MET ASP ASP LYS ALA LEU LEU VAL GLU VAL GLN LEU LEU          
SEQRES  11 X  380  GLU SER LYS THR TYR HIS ALA LEU SER ASN LEU PRO LYS          
SEQRES  12 X  380  ALA ARG ALA ALA LEU THR SER ALA ARG THR THR ALA ASN          
SEQRES  13 X  380  ALA ILE TYR CYS PRO PRO LYS LEU GLN ALA THR LEU ASP          
SEQRES  14 X  380  MET GLN SER GLY ILE ILE HIS ALA ALA GLU GLU LYS ASP          
SEQRES  15 X  380  TRP LYS THR ALA TYR SER TYR PHE TYR GLU ALA PHE GLU          
SEQRES  16 X  380  GLY TYR ASP SER ILE ASP SER PRO LYS ALA ILE THR SER          
SEQRES  17 X  380  LEU LYS TYR MET LEU LEU CYS LYS ILE MET LEU ASN THR          
SEQRES  18 X  380  PRO GLU ASP VAL GLN ALA LEU VAL SER GLY LYS LEU ALA          
SEQRES  19 X  380  LEU ARG TYR ALA GLY ARG GLN THR GLU ALA LEU LYS CYS          
SEQRES  20 X  380  VAL ALA GLN ALA SER LYS ASN ARG SER LEU ALA ASP PHE          
SEQRES  21 X  380  GLU LYS ALA LEU THR ASP TYR ARG ALA GLU LEU ARG ASP          
SEQRES  22 X  380  ASP PRO ILE ILE SER THR HIS LEU ALA LYS LEU TYR ASP          
SEQRES  23 X  380  ASN LEU LEU GLU GLN ASN LEU ILE ARG VAL ILE GLU PRO          
SEQRES  24 X  380  PHE SER ARG VAL GLN ILE GLU HIS ILE SER SER LEU ILE          
SEQRES  25 X  380  LYS LEU SER LYS ALA ASP VAL GLU ARG LYS LEU SER GLN          
SEQRES  26 X  380  MET ILE LEU ASP LYS LYS PHE HIS GLY ILE LEU ASP GLN          
SEQRES  27 X  380  GLY GLU GLY VAL LEU ILE ILE PHE ASP GLU PRO PRO VAL          
SEQRES  28 X  380  ASP LYS THR TYR GLU ALA ALA LEU GLU THR ILE GLN ASN          
SEQRES  29 X  380  MET SER LYS VAL VAL ASP SER LEU TYR ASN LYS ALA LYS          
SEQRES  30 X  380  LYS LEU THR                                                  
SEQRES   1 Y  378  PRO LYS ASN PRO ASP LEU ARG ILE ALA GLN LEU ARG PHE          
SEQRES   2 Y  378  LEU LEU SER LEU PRO GLU HIS ARG GLY ASP ALA ALA VAL          
SEQRES   3 Y  378  ARG ASP GLU LEU MET ALA ALA VAL ARG ASP ASN ASN MET          
SEQRES   4 Y  378  ALA PRO TYR TYR GLU ALA LEU CYS LYS SER LEU ASP TRP          
SEQRES   5 Y  378  GLN ILE ASP VAL ASP LEU LEU ASN LYS MET LYS LYS ALA          
SEQRES   6 Y  378  ASN GLU ASP GLU LEU LYS ARG LEU ASP GLU GLU LEU GLU          
SEQRES   7 Y  378  ASP ALA GLU LYS ASN LEU GLY GLU SER GLU ILE ARG ASP          
SEQRES   8 Y  378  ALA MET MET ALA LYS ALA GLU TYR LEU CYS ARG ILE GLY          
SEQRES   9 Y  378  ASP LYS GLU GLY ALA LEU THR ALA PHE ARG LYS THR TYR          
SEQRES  10 Y  378  ASP LYS THR VAL ALA LEU GLY HIS ARG LEU ASP ILE VAL          
SEQRES  11 Y  378  PHE TYR LEU LEU ARG ILE GLY LEU PHE TYR MET ASP ASN          
SEQRES  12 Y  378  ASP LEU ILE THR ARG ASN THR GLU LYS ALA LYS SER LEU          
SEQRES  13 Y  378  ILE GLU GLU GLY GLY ASP TRP ASP ARG ARG ASN ARG LEU          
SEQRES  14 Y  378  LYS VAL TYR GLN GLY LEU TYR CYS VAL ALA ILE ARG ASP          
SEQRES  15 Y  378  PHE LYS GLN ALA ALA GLU LEU PHE LEU ASP THR VAL SER          
SEQRES  16 Y  378  THR PHE THR SER TYR GLU LEU MET ASP TYR LYS THR PHE          
SEQRES  17 Y  378  VAL THR TYR THR VAL TYR VAL SER MET ILE ALA LEU GLU          
SEQRES  18 Y  378  ARG PRO ASP LEU ARG GLU LYS VAL ILE LYS GLY ALA GLU          
SEQRES  19 Y  378  ILE LEU GLU VAL LEU HIS SER LEU PRO ALA VAL ARG GLN          
SEQRES  20 Y  378  TYR LEU PHE SER LEU TYR GLU CYS ARG TYR SER VAL PHE          
SEQRES  21 Y  378  PHE GLN SER LEU ALA VAL VAL GLU GLN GLU MET LYS LYS          
SEQRES  22 Y  378  ASP TRP LEU PHE ALA PRO HIS TYR ARG TYR TYR VAL ARG          
SEQRES  23 Y  378  GLU MET ARG ILE HIS ALA TYR SER GLN LEU LEU GLU SER          
SEQRES  24 Y  378  TYR ARG SER LEU THR LEU GLY TYR MET ALA GLU ALA PHE          
SEQRES  25 Y  378  GLY VAL GLY VAL GLU PHE ILE ASP GLN GLU LEU SER ARG          
SEQRES  26 Y  378  PHE ILE ALA ALA GLY ARG LEU HIS CYS LYS ILE ASP LYS          
SEQRES  27 Y  378  VAL ASN GLU ILE VAL GLU THR ASN ARG PRO ASP SER LYS          
SEQRES  28 Y  378  ASN TRP GLN TYR GLN GLU THR ILE LYS LYS GLY ASP LEU          
SEQRES  29 Y  378  LEU LEU ASN ARG VAL GLN LYS LEU SER ARG VAL ILE ASN          
SEQRES  30 Y  378  MET                                                          
SEQRES   1 Z  286  ALA VAL GLN LYS VAL VAL VAL HIS PRO LEU VAL LEU LEU          
SEQRES   2 Z  286  SER VAL VAL ASP HIS PHE ASN ARG ILE GLY LYS VAL GLY          
SEQRES   3 Z  286  ASN GLN LYS ARG VAL VAL GLY VAL LEU LEU GLY SER TRP          
SEQRES   4 Z  286  GLN LYS LYS VAL LEU ASP VAL SER ASN SER PHE ALA VAL          
SEQRES   5 Z  286  PRO PHE ASP GLU ASP ASP LYS ASP ASP SER VAL TRP PHE          
SEQRES   6 Z  286  LEU ASP HIS ASP TYR LEU GLU ASN MET TYR GLY MET PHE          
SEQRES   7 Z  286  LYS LYS VAL ASN ALA ARG GLU ARG ILE VAL GLY TRP TYR          
SEQRES   8 Z  286  HIS THR GLY PRO LYS LEU HIS LYS ASN ASP ILE ALA ILE          
SEQRES   9 Z  286  ASN GLU LEU MET LYS ARG TYR CYS PRO ASN SER VAL LEU          
SEQRES  10 Z  286  VAL ILE ILE ASP VAL LYS PRO LYS ASP LEU GLY LEU PRO          
SEQRES  11 Z  286  THR GLU ALA TYR ILE SER VAL GLU GLU VAL HIS ASP ASP          
SEQRES  12 Z  286  GLY THR PRO THR SER LYS THR PHE GLU HIS VAL THR SER          
SEQRES  13 Z  286  GLU ILE GLY ALA GLU GLU ALA GLU GLU VAL GLY VAL GLU          
SEQRES  14 Z  286  HIS LEU LEU ARG ASP ILE LYS ASP THR THR VAL GLY THR          
SEQRES  15 Z  286  LEU SER GLN ARG ILE THR ASN GLN VAL HIS GLY LEU LYS          
SEQRES  16 Z  286  GLY LEU ASN SER LYS LEU LEU ASP ILE ARG SER TYR LEU          
SEQRES  17 Z  286  GLU LYS VAL ALA THR GLY LYS LEU PRO ILE ASN HIS GLN          
SEQRES  18 Z  286  ILE ILE TYR GLN LEU GLN ASP VAL PHE ASN LEU LEU PRO          
SEQRES  19 Z  286  ASP VAL SER LEU GLN GLU PHE VAL LYS ALA PHE TYR LEU          
SEQRES  20 Z  286  LYS THR ASN ASP GLN MET VAL VAL VAL TYR LEU ALA SER          
SEQRES  21 Z  286  LEU ILE ARG SER VAL VAL ALA LEU HIS ASN LEU ILE ASN          
SEQRES  22 Z  286  ASN LYS ILE ALA ASN ARG ASP ALA GLU LYS LYS GLU GLY          
SEQRES   1 a  373  VAL PRO GLY PHE LEU GLN GLN SER GLN SER SER GLY PRO          
SEQRES   2 a  373  GLY GLN PRO ALA VAL TRP HIS ARG LEU GLU GLU LEU TYR          
SEQRES   3 a  373  THR LYS LYS LEU TRP HIS GLN LEU THR LEU GLN VAL LEU          
SEQRES   4 a  373  ASP PHE VAL GLN ASP PRO CYS PHE ALA GLN GLY ASP GLY          
SEQRES   5 a  373  LEU ILE LYS LEU TYR GLU ASN PHE ILE SER GLU PHE GLU          
SEQRES   6 a  373  HIS ARG VAL ASN PRO LEU SER LEU VAL GLU ILE ILE LEU          
SEQRES   7 a  373  HIS VAL VAL ARG GLN MET THR ASP PRO ASN VAL ALA LEU          
SEQRES   8 a  373  THR PHE LEU GLU LYS THR ARG GLU LYS VAL LYS SER SER          
SEQRES   9 a  373  ASP GLU ALA VAL ILE LEU CYS LYS THR ALA ILE GLY ALA          
SEQRES  10 a  373  LEU LYS LEU ASN ILE GLY ASP LEU GLN VAL THR LYS GLU          
SEQRES  11 a  373  THR ILE GLU ASP VAL GLU GLU MET LEU ASN ASN LEU PRO          
SEQRES  12 a  373  GLY VAL THR SER VAL HIS SER ARG PHE TYR ASP LEU SER          
SEQRES  13 a  373  SER LYS TYR TYR GLN THR ILE GLY ASN HIS ALA SER TYR          
SEQRES  14 a  373  TYR LYS ASP ALA LEU ARG PHE LEU GLY CYS VAL ASP ILE          
SEQRES  15 a  373  LYS ASP LEU PRO VAL SER GLU GLN GLN GLU ARG ALA PHE          
SEQRES  16 a  373  THR LEU GLY LEU ALA GLY LEU LEU GLY GLU GLY VAL PHE          
SEQRES  17 a  373  ASN PHE GLY GLU LEU LEU MET HIS PRO VAL LEU GLU SER          
SEQRES  18 a  373  LEU ARG ASN THR ASP ARG GLN TRP LEU ILE ASP THR LEU          
SEQRES  19 a  373  TYR ALA PHE ASN SER GLY ASN VAL GLU ARG PHE GLN THR          
SEQRES  20 a  373  LEU LYS THR ALA TRP GLY GLN GLN PRO ASP LEU ALA ALA          
SEQRES  21 a  373  ASN GLU ALA GLN LEU LEU ARG LYS ILE GLN LEU LEU CYS          
SEQRES  22 a  373  LEU MET GLU MET THR PHE THR ARG PRO ALA ASN HIS ARG          
SEQRES  23 a  373  GLN LEU THR PHE GLU GLU ILE ALA LYS SER ALA LYS ILE          
SEQRES  24 a  373  THR VAL ASN GLU VAL GLU LEU LEU VAL MET LYS ALA LEU          
SEQRES  25 a  373  SER VAL GLY LEU VAL LYS GLY SER ILE ASP GLU VAL ASP          
SEQRES  26 a  373  LYS ARG VAL HIS MET THR TRP VAL GLN PRO ARG VAL LEU          
SEQRES  27 a  373  ASP LEU GLN GLN ILE LYS GLY MET LYS ASP ARG LEU GLU          
SEQRES  28 a  373  PHE TRP CYS THR ASP VAL LYS SER MET GLU MET LEU VAL          
SEQRES  29 a  373  GLU HIS GLN ALA HIS ASP ILE LEU THR                          
SEQRES   1 b  191  MET VAL LEU GLU SER THR MET VAL CYS VAL ASP ASN SER          
SEQRES   2 b  191  GLU TYR MET ARG ASN GLY ASP PHE LEU PRO THR ARG LEU          
SEQRES   3 b  191  GLN ALA GLN GLN ASP ALA VAL ASN ILE VAL CYS HIS SER          
SEQRES   4 b  191  LYS THR ARG SER ASN PRO GLU ASN ASN VAL GLY LEU ILE          
SEQRES   5 b  191  THR LEU ALA ASN ASP CYS GLU VAL LEU THR THR LEU THR          
SEQRES   6 b  191  PRO ASP THR GLY ARG ILE LEU SER LYS LEU HIS THR VAL          
SEQRES   7 b  191  GLN PRO LYS GLY LYS ILE THR PHE CYS THR GLY ILE ARG          
SEQRES   8 b  191  VAL ALA HIS LEU ALA LEU LYS HIS ARG GLN GLY LYS ASN          
SEQRES   9 b  191  HIS LYS MET ARG ILE ILE ALA PHE VAL GLY SER PRO VAL          
SEQRES  10 b  191  GLU ASP ASN GLU LYS ASP LEU VAL LYS LEU ALA LYS ARG          
SEQRES  11 b  191  LEU LYS LYS GLU LYS VAL ASN VAL ASP ILE ILE ASN PHE          
SEQRES  12 b  191  GLY GLU GLU GLU VAL ASN THR GLU LYS LEU THR ALA PHE          
SEQRES  13 b  191  VAL ASN THR LEU ASN GLY LYS ASP GLY THR GLY SER HIS          
SEQRES  14 b  191  LEU VAL THR VAL PRO PRO GLY PRO SER LEU ALA ASP ALA          
SEQRES  15 b  191  LEU ILE SER SER PRO ILE LEU ALA GLY                          
SEQRES   1 c  287  ALA VAL ASP THR ALA GLU GLN VAL TYR ILE SER SER LEU          
SEQRES   2 c  287  ALA LEU LEU LYS MET LEU LYS HIS GLY ARG ALA GLY VAL          
SEQRES   3 c  287  PRO MET GLU VAL MET GLY LEU MET LEU GLY GLU PHE VAL          
SEQRES   4 c  287  ASP ASP TYR THR VAL ARG VAL ILE ASP VAL PHE ALA MET          
SEQRES   5 c  287  PRO GLN SER GLY THR GLY VAL SER VAL GLU ALA VAL ASP          
SEQRES   6 c  287  PRO VAL PHE GLN ALA LYS MET LEU ASP MET LEU LYS GLN          
SEQRES   7 c  287  THR GLY ARG PRO GLU MET VAL VAL GLY TRP TYR HIS SER          
SEQRES   8 c  287  HIS PRO GLY PHE GLY CYS TRP LEU SER GLY VAL ASP ILE          
SEQRES   9 c  287  ASN THR GLN GLN SER PHE GLU ALA LEU SER GLU ARG ALA          
SEQRES  10 c  287  VAL ALA VAL VAL VAL ASP PRO ILE GLN SER VAL LYS GLY          
SEQRES  11 c  287  LYS VAL VAL ILE ASP ALA PHE ARG LEU ILE ASN ALA ASN          
SEQRES  12 c  287  MET MET VAL LEU GLY HIS GLU PRO ARG GLN THR THR SER          
SEQRES  13 c  287  ASN LEU GLY HIS LEU ASN LYS PRO SER ILE GLN ALA LEU          
SEQRES  14 c  287  ILE HIS GLY LEU ASN ARG HIS TYR TYR SER ILE THR ILE          
SEQRES  15 c  287  ASN TYR ARG LYS ASN GLU LEU GLU GLN LYS MET LEU LEU          
SEQRES  16 c  287  ASN LEU HIS LYS LYS SER TRP MET GLU GLY LEU THR LEU          
SEQRES  17 c  287  GLN ASP TYR SER GLU HIS CYS LYS HIS ASN GLU SER VAL          
SEQRES  18 c  287  VAL LYS GLU MET LEU GLU LEU ALA LYS ASN TYR ASN LYS          
SEQRES  19 c  287  ALA VAL GLU GLU GLU ASP LYS MET THR PRO GLU GLN LEU          
SEQRES  20 c  287  ALA ILE LYS ASN VAL GLY LYS GLN ASP PRO LYS ARG HIS          
SEQRES  21 c  287  LEU GLU GLU HIS VAL ASP VAL LEU MET THR SER ASN ILE          
SEQRES  22 c  287  VAL GLN CYS LEU ALA ALA MET LEU ASP THR VAL VAL PHE          
SEQRES  23 c  287  LYS                                                          
SEQRES   1 d  257  MET TYR GLU GLN LEU LYS GLY GLU TRP ASN ARG LYS SER          
SEQRES   2 d  257  PRO ASN LEU SER LYS CYS GLY GLU GLU LEU GLY ARG LEU          
SEQRES   3 d  257  LYS LEU VAL LEU LEU GLU LEU ASN PHE LEU PRO THR THR          
SEQRES   4 d  257  GLY THR LYS LEU THR LYS GLN GLN LEU ILE LEU ALA ARG          
SEQRES   5 d  257  ASP ILE LEU GLU ILE GLY ALA GLN TRP SER ILE LEU ARG          
SEQRES   6 d  257  LYS ASP ILE PRO SER PHE GLU ARG TYR MET ALA GLN LEU          
SEQRES   7 d  257  LYS CYS TYR TYR PHE ASP TYR LYS GLU GLN LEU PRO GLU          
SEQRES   8 d  257  SER ALA TYR MET HIS GLN LEU LEU GLY LEU ASN LEU LEU          
SEQRES   9 d  257  PHE LEU LEU SER GLN ASN ARG VAL ALA GLU PHE HIS THR          
SEQRES  10 d  257  GLU LEU GLU ARG LEU PRO ALA LYS ASP ILE GLN THR ASN          
SEQRES  11 d  257  VAL TYR ILE LYS HIS PRO VAL SER LEU GLU GLN TYR LEU          
SEQRES  12 d  257  MET GLU GLY SER TYR ASN LYS VAL PHE LEU ALA LYS GLY          
SEQRES  13 d  257  ASN ILE PRO ALA GLU SER TYR THR PHE PHE ILE ASP ILE          
SEQRES  14 d  257  LEU LEU ASP THR ILE ARG ASP GLU ILE ALA GLY CYS ILE          
SEQRES  15 d  257  GLU LYS ALA TYR GLU LYS ILE LEU PHE THR GLU ALA THR          
SEQRES  16 d  257  ARG ILE LEU PHE PHE ASN THR PRO LYS LYS MET THR ASP          
SEQRES  17 d  257  TYR ALA LYS LYS ARG GLY TRP VAL LEU GLY PRO ASN ASN          
SEQRES  18 d  257  TYR TYR SER PHE ALA SER GLN GLN GLN LYS PRO GLU ASP          
SEQRES  19 d  257  THR THR ILE PRO SER THR GLU LEU ALA LYS GLN VAL ILE          
SEQRES  20 d  257  GLU TYR ALA ARG GLN LEU GLU MET ILE VAL                      
SEQRES   1 e   70  MET SER GLU LYS LYS GLN PRO VAL ASP UNK UNK UNK UNK          
SEQRES   2 e   70  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   3 e   70  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   4 e   70  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK          
SEQRES   5 e   70  UNK UNK UNK LEU ARG ALA GLU LEU GLU LYS HIS GLY TYR          
SEQRES   6 e   70  LYS MET GLU THR SER                                          
SEQRES   1 A  361  ALA PRO PRO ALA LEU TRP ASP LEU ALA ALA ASP LYS GLN          
SEQRES   2 A  361  THR LEU GLN SER GLU GLN PRO LEU GLN VAL ALA ARG CYS          
SEQRES   3 A  361  THR LYS ILE ILE ASN ALA ASP SER GLU ASP PRO LYS TYR          
SEQRES   4 A  361  ILE ILE ASN VAL LYS GLN PHE ALA LYS PHE VAL VAL ASP          
SEQRES   5 A  361  LEU SER ASP GLN VAL ALA PRO THR ASP ILE GLU GLU GLY          
SEQRES   6 A  361  MET ARG VAL GLY VAL ASP ARG ASN LYS TYR GLN ILE HIS          
SEQRES   7 A  361  ILE PRO LEU PRO PRO LYS ILE ASP PRO THR VAL THR MET          
SEQRES   8 A  361  MET GLN VAL GLU GLU LYS PRO ASP VAL THR TYR SER ASP          
SEQRES   9 A  361  VAL GLY GLY CYS LYS GLU GLN ILE GLU LYS LEU ARG GLU          
SEQRES  10 A  361  VAL VAL GLU THR PRO LEU LEU HIS PRO GLU ARG PHE VAL          
SEQRES  11 A  361  ASN LEU GLY ILE GLU PRO PRO LYS GLY VAL LEU LEU PHE          
SEQRES  12 A  361  GLY PRO PRO GLY THR GLY LYS THR LEU CYS ALA ARG ALA          
SEQRES  13 A  361  VAL ALA ASN ARG THR ASP ALA CYS PHE ILE ARG VAL ILE          
SEQRES  14 A  361  GLY SER GLU LEU VAL GLN LYS TYR VAL GLY GLU GLY ALA          
SEQRES  15 A  361  ARG MET VAL ARG GLU LEU PHE GLU MET ALA ARG THR LYS          
SEQRES  16 A  361  LYS ALA CYS LEU ILE PHE PHE ASP GLU ILE ASP ALA ILE          
SEQRES  17 A  361  GLY GLY ALA ARG PHE ASP ASP GLY ALA GLY GLY ASP ASN          
SEQRES  18 A  361  GLU VAL GLN ARG THR MET LEU GLU LEU ILE ASN GLN LEU          
SEQRES  19 A  361  ASP GLY PHE ASP PRO ARG GLY ASN ILE LYS VAL LEU MET          
SEQRES  20 A  361  ALA THR ASN ARG PRO ASP THR LEU ASP PRO ALA LEU MET          
SEQRES  21 A  361  ARG PRO GLY ARG LEU ASP ARG LYS ILE GLU PHE SER LEU          
SEQRES  22 A  361  PRO ASP LEU GLU GLY ARG THR HIS ILE PHE LYS ILE HIS          
SEQRES  23 A  361  ALA ARG SER MET SER VAL GLU ARG ASP ILE ARG PHE GLU          
SEQRES  24 A  361  LEU LEU ALA ARG LEU CYS PRO ASN SER THR GLY ALA GLU          
SEQRES  25 A  361  ILE ARG SER VAL CYS THR GLU ALA GLY MET PHE ALA ILE          
SEQRES  26 A  361  ARG ALA ARG ARG LYS ILE ALA THR GLU LYS ASP PHE LEU          
SEQRES  27 A  361  GLU ALA VAL ASN LYS VAL ILE LYS SER TYR ALA LYS PHE          
SEQRES  28 A  361  SER ALA THR PRO ARG TYR MET THR TYR ASN                      
SEQRES   1 B  341  GLU GLU GLU ARG SER LYS VAL ASP ASP LEU ARG GLY THR          
SEQRES   2 B  341  PRO MET SER VAL GLY THR LEU GLU GLU ILE ILE ASP ASP          
SEQRES   3 B  341  ASN HIS ALA ILE VAL SER THR SER VAL GLY SER GLU HIS          
SEQRES   4 B  341  TYR VAL SER ILE LEU SER PHE VAL ASP LYS ASP LEU LEU          
SEQRES   5 B  341  GLU PRO GLY CYS SER VAL LEU LEU ASN HIS LYS VAL HIS          
SEQRES   6 B  341  ALA VAL ILE GLY VAL LEU MET ASP ASP THR ASP PRO LEU          
SEQRES   7 B  341  VAL THR VAL MET LYS VAL GLU LYS ALA PRO GLN GLU THR          
SEQRES   8 B  341  TYR ALA ASP ILE GLY GLY LEU ASP ASN GLN ILE GLN GLU          
SEQRES   9 B  341  ILE LYS GLU SER VAL GLU LEU PRO LEU THR HIS PRO GLU          
SEQRES  10 B  341  TYR TYR GLU GLU MET GLY ILE LYS PRO PRO LYS GLY VAL          
SEQRES  11 B  341  ILE LEU TYR GLY PRO PRO GLY THR GLY LYS THR LEU LEU          
SEQRES  12 B  341  ALA LYS ALA VAL ALA ASN GLN THR SER ALA THR PHE LEU          
SEQRES  13 B  341  ARG VAL VAL GLY SER GLU LEU ILE GLN LYS TYR LEU GLY          
SEQRES  14 B  341  ASP GLY PRO LYS LEU VAL ARG GLU LEU PHE ARG VAL ALA          
SEQRES  15 B  341  GLU GLU HIS ALA PRO SER ILE VAL PHE ILE ASP GLU ILE          
SEQRES  16 B  341  ASP ALA ILE GLY THR LYS ARG TYR ASP SER ASN SER GLY          
SEQRES  17 B  341  GLY GLU ARG GLU ILE GLN ARG THR MET LEU GLU LEU LEU          
SEQRES  18 B  341  ASN GLN LEU ASP GLY PHE ASP SER ARG GLY ASP VAL LYS          
SEQRES  19 B  341  VAL ILE MET ALA THR ASN ARG ILE GLU THR LEU ASP PRO          
SEQRES  20 B  341  ALA LEU ILE ARG PRO GLY ARG ILE ASP ARG LYS ILE GLU          
SEQRES  21 B  341  PHE PRO LEU PRO ASP GLU LYS THR LYS LYS ARG ILE PHE          
SEQRES  22 B  341  GLN ILE HIS THR SER ARG MET THR LEU ALA ASP ASP VAL          
SEQRES  23 B  341  THR LEU ASP ASP LEU ILE MET ALA LYS ASP ASP LEU SER          
SEQRES  24 B  341  GLY ALA ASP ILE LYS ALA ILE CYS THR GLU ALA GLY LEU          
SEQRES  25 B  341  MET ALA LEU ARG GLU ARG ARG MET LYS VAL THR ASN GLU          
SEQRES  26 B  341  ASP PHE LYS LYS SER LYS GLU ASN VAL LEU TYR LYS LYS          
SEQRES  27 B  341  GLN GLU GLY                                                  
SEQRES   1 C  384  LEU GLU GLU GLY LYS ALA GLY SER GLY LEU ARG GLN TYR          
SEQRES   2 C  384  TYR LEU SER LYS ILE GLU GLU LEU GLN LEU ILE VAL ASN          
SEQRES   3 C  384  ASP LYS SER GLN ASN LEU ARG ARG LEU GLN ALA GLN ARG          
SEQRES   4 C  384  ASN GLU LEU ASN ALA LYS VAL ARG LEU LEU ARG GLU GLU          
SEQRES   5 C  384  LEU GLN LEU LEU GLN GLU GLN GLY SER TYR VAL GLY GLU          
SEQRES   6 C  384  VAL VAL ARG ALA MET ASP LYS LYS LYS VAL LEU VAL LYS          
SEQRES   7 C  384  VAL HIS PRO GLU GLY LYS PHE VAL VAL ASP VAL ASP LYS          
SEQRES   8 C  384  ASN ILE ASP ILE ASN ASP VAL THR PRO ASN CYS ARG VAL          
SEQRES   9 C  384  ALA LEU ARG ASN ASP SER TYR THR LEU HIS LYS ILE LEU          
SEQRES  10 C  384  PRO ASN LYS VAL ASP PRO LEU VAL SER LEU MET MET VAL          
SEQRES  11 C  384  GLU LYS VAL PRO ASP SER THR TYR GLU MET ILE GLY GLY          
SEQRES  12 C  384  LEU ASP LYS GLN ILE LYS GLU ILE LYS GLU VAL ILE GLU          
SEQRES  13 C  384  LEU PRO VAL LYS HIS PRO GLU LEU PHE GLU ALA LEU GLY          
SEQRES  14 C  384  ILE ALA GLN PRO LYS GLY VAL LEU LEU TYR GLY PRO PRO          
SEQRES  15 C  384  GLY THR GLY LYS THR LEU LEU ALA ARG ALA VAL ALA HIS          
SEQRES  16 C  384  HIS THR ASP CYS THR PHE ILE ARG VAL SER GLY SER GLU          
SEQRES  17 C  384  LEU VAL GLN LYS PHE ILE GLY GLU GLY ALA ARG MET VAL          
SEQRES  18 C  384  ARG GLU LEU PHE VAL MET ALA ARG GLU HIS ALA PRO SER          
SEQRES  19 C  384  ILE ILE PHE MET ASP GLU ILE ASP SER ILE GLY SER SER          
SEQRES  20 C  384  ARG LEU GLU GLY GLY SER GLY GLY ASP SER GLU VAL GLN          
SEQRES  21 C  384  ARG THR MET LEU GLU LEU LEU ASN GLN LEU ASP GLY PHE          
SEQRES  22 C  384  GLU ALA THR LYS ASN ILE LYS VAL ILE MET ALA THR ASN          
SEQRES  23 C  384  ARG ILE ASP ILE LEU ASP SER ALA LEU LEU ARG PRO GLY          
SEQRES  24 C  384  ARG ILE ASP ARG LYS ILE GLU PHE PRO PRO PRO ASN GLU          
SEQRES  25 C  384  GLU ALA ARG LEU ASP ILE LEU LYS ILE HIS SER ARG LYS          
SEQRES  26 C  384  MET ASN LEU THR ARG GLY ILE ASN LEU ARG LYS ILE ALA          
SEQRES  27 C  384  GLU LEU MET PRO GLY ALA SER GLY ALA GLU VAL LYS GLY          
SEQRES  28 C  384  VAL CYS THR GLU ALA GLY MET TYR ALA LEU ARG GLU ARG          
SEQRES  29 C  384  ARG VAL HIS VAL THR GLN GLU ASP PHE GLU MET ALA VAL          
SEQRES  30 C  384  ALA LYS VAL MET GLN LYS ASP                                  
SEQRES   1 D  380  ASP LEU TYR SER ARG TYR LYS LYS LEU GLN GLN GLU LEU          
SEQRES   2 D  380  GLU PHE LEU GLU VAL GLN GLU GLU TYR ILE LYS ASP GLU          
SEQRES   3 D  380  GLN LYS ASN LEU LYS LYS GLU PHE LEU HIS ALA GLN GLU          
SEQRES   4 D  380  GLU VAL LYS ARG ILE GLN SER ILE PRO LEU VAL ILE GLY          
SEQRES   5 D  380  GLN PHE LEU GLU ALA VAL ASP GLN ASN THR ALA ILE VAL          
SEQRES   6 D  380  GLY SER THR THR GLY SER ASN TYR TYR VAL ARG ILE LEU          
SEQRES   7 D  380  SER THR ILE ASP ARG GLU LEU LEU LYS PRO ASN ALA SER          
SEQRES   8 D  380  VAL ALA LEU HIS LYS HIS SER ASN ALA LEU VAL ASP VAL          
SEQRES   9 D  380  LEU PRO PRO GLU ALA ASP SER SER ILE MET MET LEU THR          
SEQRES  10 D  380  SER ASP GLN LYS PRO ASP VAL MET TYR ALA ASP ILE GLY          
SEQRES  11 D  380  GLY MET ASP ILE GLN LYS GLN GLU VAL ARG GLU ALA VAL          
SEQRES  12 D  380  GLU LEU PRO LEU THR HIS PHE GLU LEU TYR LYS GLN ILE          
SEQRES  13 D  380  GLY ILE ASP PRO PRO ARG GLY VAL LEU MET TYR GLY PRO          
SEQRES  14 D  380  PRO GLY CYS GLY LYS THR MET LEU ALA LYS ALA VAL ALA          
SEQRES  15 D  380  HIS HIS THR THR ALA ALA PHE ILE ARG VAL VAL GLY SER          
SEQRES  16 D  380  GLU PHE VAL GLN LYS TYR LEU GLY GLU GLY PRO ARG MET          
SEQRES  17 D  380  VAL ARG ASP VAL PHE ARG LEU ALA LYS GLU ASN ALA PRO          
SEQRES  18 D  380  ALA ILE ILE PHE ILE ASP GLU ILE ASP ALA ILE ALA THR          
SEQRES  19 D  380  LYS ARG PHE ASP ALA GLN THR GLY ALA ASP ARG GLU VAL          
SEQRES  20 D  380  GLN ARG ILE LEU LEU GLU LEU LEU ASN GLN MET ASP GLY          
SEQRES  21 D  380  PHE ASP GLN ASN VAL ASN VAL LYS VAL ILE MET ALA THR          
SEQRES  22 D  380  ASN ARG ALA ASP THR LEU ASP PRO ALA LEU LEU ARG PRO          
SEQRES  23 D  380  GLY ARG LEU ASP ARG LYS ILE GLU PHE PRO LEU PRO ASP          
SEQRES  24 D  380  ARG ARG GLN LYS ARG LEU ILE PHE SER THR ILE THR SER          
SEQRES  25 D  380  LYS MET ASN LEU SER GLU GLU VAL ASP LEU GLU ASP TYR          
SEQRES  26 D  380  VAL ALA ARG PRO ASP LYS ILE SER GLY ALA ASP ILE ASN          
SEQRES  27 D  380  SER ILE CYS GLN GLU SER GLY MET LEU ALA VAL ARG GLU          
SEQRES  28 D  380  ASN ARG TYR ILE VAL LEU ALA LYS ASP PHE GLU LYS ALA          
SEQRES  29 D  380  TYR LYS THR VAL ILE LYS LYS ASP GLU GLN GLU HIS GLU          
SEQRES  30 D  380  PHE TYR LYS                                                  
SEQRES   1 E  353  THR LYS GLN TYR GLU LYS SER GLU ASN ASP LEU LYS ALA          
SEQRES   2 E  353  LEU GLN SER VAL GLY GLN ILE VAL GLY GLU VAL LEU LYS          
SEQRES   3 E  353  GLN LEU THR GLU GLU LYS PHE ILE VAL LYS ALA THR ASN          
SEQRES   4 E  353  GLY PRO ARG TYR VAL VAL GLY CYS ARG ARG GLN LEU ASP          
SEQRES   5 E  353  LYS SER LYS LEU LYS PRO GLY THR ARG VAL ALA LEU ASP          
SEQRES   6 E  353  MET THR THR LEU THR ILE MET ARG TYR LEU PRO ARG GLU          
SEQRES   7 E  353  VAL ASP PRO LEU VAL TYR ASN MET SER HIS GLU ASP PRO          
SEQRES   8 E  353  GLY ASN VAL SER TYR SER GLU ILE GLY GLY LEU SER GLU          
SEQRES   9 E  353  GLN ILE ARG GLU LEU ARG GLU VAL ILE GLU LEU PRO LEU          
SEQRES  10 E  353  THR ASN PRO GLU LEU PHE GLN ARG VAL GLY ILE ILE PRO          
SEQRES  11 E  353  PRO LYS GLY CYS LEU LEU TYR GLY PRO PRO GLY THR GLY          
SEQRES  12 E  353  LYS THR LEU LEU ALA ARG ALA VAL ALA SER GLN LEU ASP          
SEQRES  13 E  353  CYS ASN PHE LEU LYS VAL VAL SER SER SER ILE VAL ASP          
SEQRES  14 E  353  LYS TYR ILE GLY GLU SER ALA ARG LEU ILE ARG GLU MET          
SEQRES  15 E  353  PHE ASN TYR ALA ARG ASP HIS GLN PRO CYS ILE ILE PHE          
SEQRES  16 E  353  MET ASP GLU ILE ASP ALA ILE GLY GLY ARG ARG PHE SER          
SEQRES  17 E  353  GLU GLY THR SER ALA ASP ARG GLU ILE GLN ARG THR LEU          
SEQRES  18 E  353  MET GLU LEU LEU ASN GLN MET ASP GLY PHE ASP THR LEU          
SEQRES  19 E  353  HIS ARG VAL LYS MET ILE MET ALA THR ASN ARG PRO ASP          
SEQRES  20 E  353  THR LEU ASP PRO ALA LEU LEU ARG PRO GLY ARG LEU ASP          
SEQRES  21 E  353  ARG LYS ILE HIS ILE ASP LEU PRO ASN GLU GLN ALA ARG          
SEQRES  22 E  353  LEU ASP ILE LEU LYS ILE HIS ALA GLY PRO ILE THR LYS          
SEQRES  23 E  353  HIS GLY GLU ILE ASP TYR GLU ALA ILE VAL LYS LEU SER          
SEQRES  24 E  353  ASP GLY PHE ASN GLY ALA ASP LEU ARG ASN VAL CYS THR          
SEQRES  25 E  353  GLU ALA GLY MET PHE ALA ILE ARG ALA ASP HIS ASP PHE          
SEQRES  26 E  353  VAL VAL GLN GLU ASP PHE MET LYS ALA VAL ARG LYS VAL          
SEQRES  27 E  353  ALA ASP SER LYS LYS LEU GLU SER LYS LEU ASP TYR LYS          
SEQRES  28 E  353  PRO VAL                                                      
SEQRES   1 F  377  THR HIS GLU LEU GLN ALA MET LYS ASP LYS ILE LYS GLU          
SEQRES   2 F  377  ASN SER GLU LYS ILE LYS VAL ASN LYS THR LEU PRO TYR          
SEQRES   3 F  377  LEU VAL SER ASN VAL ILE GLU LEU LEU ASP VAL ASP PRO          
SEQRES   4 F  377  ASN ASP GLN GLU GLU ASP GLY ALA ASN ILE ASP LEU ASP          
SEQRES   5 F  377  SER GLN ARG LYS GLY LYS CYS ALA VAL ILE LYS THR SER          
SEQRES   6 F  377  THR ARG GLN THR TYR PHE LEU PRO VAL ILE GLY LEU VAL          
SEQRES   7 F  377  ASP ALA GLU LYS LEU LYS PRO GLY ASP LEU VAL GLY VAL          
SEQRES   8 F  377  ASN LYS ASP SER TYR LEU ILE LEU GLU THR LEU PRO THR          
SEQRES   9 F  377  GLU TYR ASP SER ARG VAL LYS ALA MET GLU VAL ASP GLU          
SEQRES  10 F  377  ARG PRO THR GLU GLN TYR SER ASP ILE GLY GLY LEU ASP          
SEQRES  11 F  377  LYS GLN ILE GLN GLU LEU VAL GLU ALA ILE VAL LEU PRO          
SEQRES  12 F  377  MET ASN HIS LYS GLU LYS PHE GLU ASN LEU GLY ILE GLN          
SEQRES  13 F  377  PRO PRO LYS GLY VAL LEU MET TYR GLY PRO PRO GLY THR          
SEQRES  14 F  377  GLY LYS THR LEU LEU ALA ARG ALA CYS ALA ALA GLN THR          
SEQRES  15 F  377  LYS ALA THR PHE LEU LYS LEU ALA GLY PRO GLN LEU VAL          
SEQRES  16 F  377  GLN MET PHE ILE GLY ASP GLY ALA LYS LEU VAL ARG ASP          
SEQRES  17 F  377  ALA PHE ALA LEU ALA LYS GLU LYS ALA PRO SER ILE ILE          
SEQRES  18 F  377  PHE ILE ASP GLU LEU ASP ALA ILE GLY THR LYS ARG PHE          
SEQRES  19 F  377  ASP SER GLU LYS ALA GLY ASP ARG GLU VAL GLN ARG THR          
SEQRES  20 F  377  MET LEU GLU LEU LEU ASN GLN LEU ASP GLY PHE GLN PRO          
SEQRES  21 F  377  ASN THR GLN VAL LYS VAL ILE ALA ALA THR ASN ARG VAL          
SEQRES  22 F  377  ASP ILE LEU ASP PRO ALA LEU LEU ARG SER GLY ARG LEU          
SEQRES  23 F  377  ASP ARG LYS ILE GLU PHE PRO MET PRO ASN GLU GLU ALA          
SEQRES  24 F  377  ARG ALA ARG ILE MET GLN ILE HIS SER ARG LYS MET ASN          
SEQRES  25 F  377  VAL SER PRO ASP VAL ASN TYR GLU GLU LEU ALA ARG CYS          
SEQRES  26 F  377  THR ASP ASP PHE ASN GLY ALA GLN CYS LYS ALA VAL CYS          
SEQRES  27 F  377  VAL GLU ALA GLY MET ILE ALA LEU ARG ARG GLY ALA THR          
SEQRES  28 F  377  GLU LEU THR HIS GLU ASP TYR MET GLU GLY ILE LEU GLU          
SEQRES  29 F  377  VAL GLN ALA LYS LYS LYS ALA ASN LEU GLN TYR TYR ALA          
SEQRES   1 G  240  SER SER ALA GLY PHE ASP ARG HIS ILE THR ILE PHE SER          
SEQRES   2 G  240  PRO GLU GLY ARG LEU TYR GLN VAL GLU TYR ALA PHE LYS          
SEQRES   3 G  240  ALA ILE ASN GLN GLY GLY LEU THR SER VAL ALA VAL ARG          
SEQRES   4 G  240  GLY LYS ASP CYS ALA VAL ILE VAL THR GLN LYS LYS VAL          
SEQRES   5 G  240  PRO ASP LYS LEU LEU ASP SER SER THR VAL THR HIS LEU          
SEQRES   6 G  240  PHE LYS ILE THR GLU ASN ILE GLY CYS VAL MET THR GLY          
SEQRES   7 G  240  MET THR ALA ASP SER ARG SER GLN VAL GLN ARG ALA ARG          
SEQRES   8 G  240  TYR GLU ALA ALA ASN TRP LYS TYR LYS TYR GLY TYR GLU          
SEQRES   9 G  240  ILE PRO VAL ASP MET LEU CYS LYS ARG ILE ALA ASP ILE          
SEQRES  10 G  240  SER GLN VAL TYR THR GLN ASN ALA GLU MET ARG PRO LEU          
SEQRES  11 G  240  GLY CYS CYS MET ILE LEU ILE GLY ILE ASP GLU GLU GLN          
SEQRES  12 G  240  GLY PRO GLN VAL TYR LYS CYS ASP PRO ALA GLY TYR TYR          
SEQRES  13 G  240  CYS GLY PHE LYS ALA THR ALA ALA GLY VAL LYS GLN THR          
SEQRES  14 G  240  GLU SER THR SER PHE LEU GLU LYS LYS VAL LYS LYS LYS          
SEQRES  15 G  240  PHE ASP TRP THR PHE GLU GLN THR VAL GLU THR ALA ILE          
SEQRES  16 G  240  THR CYS LEU SER THR VAL LEU SER ILE ASP PHE LYS PRO          
SEQRES  17 G  240  SER GLU ILE GLU VAL GLY VAL VAL THR VAL GLU ASN PRO          
SEQRES  18 G  240  LYS PHE ARG ILE LEU THR GLU ALA GLU ILE ASP ALA HIS          
SEQRES  19 G  240  LEU VAL ALA LEU ALA GLU                                      
SEQRES   1 H  232  GLU ARG GLY TYR SER PHE SER LEU THR THR PHE SER PRO          
SEQRES   2 H  232  SER GLY LYS LEU VAL GLN ILE GLU TYR ALA LEU ALA ALA          
SEQRES   3 H  232  VAL ALA GLY GLY ALA PRO SER VAL GLY ILE LYS ALA ALA          
SEQRES   4 H  232  ASN GLY VAL VAL LEU ALA THR GLU LYS LYS GLN LYS SER          
SEQRES   5 H  232  ILE LEU TYR ASP GLU ARG SER VAL HIS LYS VAL GLU PRO          
SEQRES   6 H  232  ILE THR LYS HIS ILE GLY LEU VAL TYR SER GLY MET GLY          
SEQRES   7 H  232  PRO ASP TYR ARG VAL LEU VAL HIS ARG ALA ARG LYS LEU          
SEQRES   8 H  232  ALA GLN GLN TYR TYR LEU VAL TYR GLN GLU PRO ILE PRO          
SEQRES   9 H  232  THR ALA GLN LEU VAL GLN ARG VAL ALA SER VAL MET GLN          
SEQRES  10 H  232  GLU TYR THR GLN SER GLY GLY VAL ARG PRO PHE GLY VAL          
SEQRES  11 H  232  SER LEU LEU ILE CYS GLY TRP ASN GLU GLY ARG PRO TYR          
SEQRES  12 H  232  LEU PHE GLN SER ASP PRO SER GLY ALA TYR PHE ALA TRP          
SEQRES  13 H  232  LYS ALA THR ALA MET GLY LYS ASN TYR VAL ASN GLY LYS          
SEQRES  14 H  232  THR PHE LEU GLU LYS ARG TYR ASN GLU ASP LEU GLU LEU          
SEQRES  15 H  232  GLU ASP ALA ILE HIS THR ALA ILE LEU THR LEU LYS GLU          
SEQRES  16 H  232  SER PHE GLU GLY GLN MET THR GLU ASP ASN ILE GLU VAL          
SEQRES  17 H  232  GLY ILE CYS ASN GLU ALA GLY PHE ARG ARG LEU THR PRO          
SEQRES  18 H  232  THR GLU VAL LYS ASP TYR LEU ALA ALA ILE ALA                  
SEQRES   1 I  250  SER ARG ARG TYR ASP SER ARG THR THR ILE PHE SER PRO          
SEQRES   2 I  250  GLU GLY ARG LEU TYR GLN VAL GLU TYR ALA MET GLU ALA          
SEQRES   3 I  250  ILE GLY HIS ALA GLY THR CYS LEU GLY ILE LEU ALA ASN          
SEQRES   4 I  250  ASP GLY VAL LEU LEU ALA ALA GLU ARG ARG ASN ILE HIS          
SEQRES   5 I  250  LYS LEU LEU ASP GLU VAL PHE PHE SER GLU LYS ILE TYR          
SEQRES   6 I  250  LYS LEU ASN GLU ASP MET ALA CYS SER VAL ALA GLY ILE          
SEQRES   7 I  250  THR SER ASP ALA ASN VAL LEU THR ASN GLU LEU ARG LEU          
SEQRES   8 I  250  ILE ALA GLN ARG TYR LEU LEU GLN TYR GLN GLU PRO ILE          
SEQRES   9 I  250  PRO CYS GLU GLN LEU VAL THR ALA LEU CYS ASP ILE LYS          
SEQRES  10 I  250  GLN ALA TYR THR GLN PHE GLY GLY LYS ARG PRO PHE GLY          
SEQRES  11 I  250  VAL SER LEU LEU TYR ILE GLY TRP ASP LYS HIS TYR GLY          
SEQRES  12 I  250  PHE GLN LEU TYR GLN SER ASP PRO SER GLY ASN TYR GLY          
SEQRES  13 I  250  GLY TRP LYS ALA THR CYS ILE GLY ASN ASN SER ALA ALA          
SEQRES  14 I  250  ALA VAL SER MET LEU LYS GLN ASP TYR LYS GLU GLY GLU          
SEQRES  15 I  250  MET THR LEU LYS SER ALA LEU ALA LEU ALA ILE LYS VAL          
SEQRES  16 I  250  LEU ASN LYS THR MET ASP VAL SER LYS LEU SER ALA GLU          
SEQRES  17 I  250  LYS VAL GLU ILE ALA THR LEU THR ARG GLU ASN GLY LYS          
SEQRES  18 I  250  THR VAL ILE ARG VAL LEU LYS GLN LYS GLU VAL GLU GLN          
SEQRES  19 I  250  LEU ILE LYS LYS HIS GLU GLU GLU GLU ALA LYS ALA GLU          
SEQRES  20 I  250  ARG GLU LYS                                                  
SEQRES   1 J  243  SER TYR ASP ARG ALA ILE THR VAL PHE SER PRO ASP GLY          
SEQRES   2 J  243  HIS LEU PHE GLN VAL GLU TYR ALA GLN GLU ALA VAL LYS          
SEQRES   3 J  243  LYS GLY SER THR ALA VAL GLY VAL ARG GLY ARG ASP ILE          
SEQRES   4 J  243  VAL VAL LEU GLY VAL GLU LYS LYS SER VAL ALA LYS LEU          
SEQRES   5 J  243  GLN ASP GLU ARG THR VAL ARG LYS ILE CYS ALA LEU ASP          
SEQRES   6 J  243  ASP ASN VAL CYS MET ALA PHE ALA GLY LEU THR ALA ASP          
SEQRES   7 J  243  ALA ARG ILE VAL ILE ASN ARG ALA ARG VAL GLU CYS GLN          
SEQRES   8 J  243  SER HIS ARG LEU THR VAL GLU ASP PRO VAL THR VAL GLU          
SEQRES   9 J  243  TYR ILE THR ARG TYR ILE ALA SER LEU LYS GLN ARG TYR          
SEQRES  10 J  243  THR GLN SER ASN GLY ARG ARG PRO PHE GLY ILE SER ALA          
SEQRES  11 J  243  LEU ILE VAL GLY PHE ASP PHE ASP GLY THR PRO ARG LEU          
SEQRES  12 J  243  TYR GLN THR ASP PRO SER GLY THR TYR HIS ALA TRP LYS          
SEQRES  13 J  243  ALA ASN ALA ILE GLY ARG GLY ALA LYS SER VAL ARG GLU          
SEQRES  14 J  243  PHE LEU GLU LYS ASN TYR THR ASP GLU ALA ILE GLU THR          
SEQRES  15 J  243  ASP ASP LEU THR ILE LYS LEU VAL ILE LYS ALA LEU LEU          
SEQRES  16 J  243  GLU VAL VAL GLN SER GLY GLY LYS ASN ILE GLU LEU ALA          
SEQRES  17 J  243  VAL MET ARG ARG ASP GLN SER LEU LYS ILE LEU ASN PRO          
SEQRES  18 J  243  GLU GLU ILE GLU LYS TYR VAL ALA GLU ILE GLU LYS GLU          
SEQRES  19 J  243  LYS GLU GLU ASN GLU LYS LYS LYS GLN                          
SEQRES   1 K  234  TYR ASP ARG GLY VAL ASN THR PHE SER PRO GLU GLY ARG          
SEQRES   2 K  234  LEU PHE GLN VAL GLU TYR ALA ILE GLU ALA ILE LYS LEU          
SEQRES   3 K  234  GLY SER THR ALA ILE GLY ILE GLN THR SER GLU GLY VAL          
SEQRES   4 K  234  CYS LEU ALA VAL GLU LYS ARG ILE THR SER PRO LEU MET          
SEQRES   5 K  234  GLU PRO SER SER ILE GLU LYS ILE VAL GLU ILE ASP ALA          
SEQRES   6 K  234  HIS ILE GLY CYS ALA MET SER GLY LEU ILE ALA ASP ALA          
SEQRES   7 K  234  LYS THR LEU ILE ASP LYS ALA ARG VAL GLU THR GLN ASN          
SEQRES   8 K  234  HIS TRP PHE THR TYR ASN GLU THR MET THR VAL GLU SER          
SEQRES   9 K  234  VAL THR GLN ALA VAL SER ASN LEU ALA LEU GLN PHE GLY          
SEQRES  10 K  234  GLU GLU ASP ALA ASP PRO GLY ALA MET SER ARG PRO PHE          
SEQRES  11 K  234  GLY VAL ALA LEU LEU PHE GLY GLY VAL ASP GLU LYS GLY          
SEQRES  12 K  234  PRO GLN LEU PHE HIS MET ASP PRO SER GLY THR PHE VAL          
SEQRES  13 K  234  GLN CYS ASP ALA ARG ALA ILE GLY SER ALA SER GLU GLY          
SEQRES  14 K  234  ALA GLN SER SER LEU GLN GLU VAL TYR HIS LYS SER MET          
SEQRES  15 K  234  THR LEU LYS GLU ALA ILE LYS SER SER LEU ILE ILE LEU          
SEQRES  16 K  234  LYS GLN VAL MET GLU GLU LYS LEU ASN ALA THR ASN ILE          
SEQRES  17 K  234  GLU LEU ALA THR VAL GLN PRO GLY GLN ASN PHE HIS MET          
SEQRES  18 K  234  PHE THR LYS GLU GLU LEU GLU GLU VAL ILE LYS ASP ILE          
SEQRES   1 L  238  ASN GLN TYR ASP ASN ASP VAL THR VAL TRP SER PRO GLN          
SEQRES   2 L  238  GLY ARG ILE HIS GLN ILE GLU TYR ALA MET GLU ALA VAL          
SEQRES   3 L  238  LYS GLN GLY SER ALA THR VAL GLY LEU LYS SER LYS THR          
SEQRES   4 L  238  HIS ALA VAL LEU VAL ALA LEU LYS ARG ALA GLN SER GLU          
SEQRES   5 L  238  LEU ALA ALA HIS GLN LYS LYS ILE LEU HIS VAL ASP ASN          
SEQRES   6 L  238  HIS ILE GLY ILE SER ILE ALA GLY LEU THR ALA ASP ALA          
SEQRES   7 L  238  ARG LEU LEU CYS ASN PHE MET ARG GLN GLU CYS LEU ASP          
SEQRES   8 L  238  SER ARG PHE VAL PHE ASP ARG PRO LEU PRO VAL SER ARG          
SEQRES   9 L  238  LEU VAL SER LEU ILE GLY SER LYS THR GLN ILE PRO THR          
SEQRES  10 L  238  GLN ARG TYR GLY ARG ARG PRO TYR GLY VAL GLY LEU LEU          
SEQRES  11 L  238  ILE ALA GLY TYR ASP ASP MET GLY PRO HIS ILE PHE GLN          
SEQRES  12 L  238  THR CYS PRO SER ALA ASN TYR PHE ASP CYS ARG ALA MET          
SEQRES  13 L  238  SER ILE GLY ALA ARG SER GLN SER ALA ARG THR TYR LEU          
SEQRES  14 L  238  GLU ARG HIS MET SER GLU PHE MET GLU CYS ASN LEU ASN          
SEQRES  15 L  238  GLU LEU VAL LYS HIS GLY LEU ARG ALA LEU ARG GLU THR          
SEQRES  16 L  238  LEU PRO ALA GLU GLN ASP LEU THR THR LYS ASN VAL SER          
SEQRES  17 L  238  ILE GLY ILE VAL GLY LYS ASP LEU GLU PHE THR ILE TYR          
SEQRES  18 L  238  ASP ASP ASP ASP VAL SER PRO PHE LEU GLU GLY LEU GLU          
SEQRES  19 L  238  GLU ARG PRO GLN                                              
SEQRES   1 M  245  SER SER ILE GLY THR GLY TYR ASP LEU SER ALA SER THR          
SEQRES   2 M  245  PHE SER PRO ASP GLY ARG VAL PHE GLN VAL GLU TYR ALA          
SEQRES   3 M  245  MET LYS ALA VAL GLU ASN SER SER THR ALA ILE GLY ILE          
SEQRES   4 M  245  ARG CYS LYS ASP GLY VAL VAL PHE GLY VAL GLU LYS LEU          
SEQRES   5 M  245  VAL LEU SER LYS LEU TYR GLU GLU GLY SER ASN LYS ARG          
SEQRES   6 M  245  LEU PHE ASN VAL ASP ARG HIS VAL GLY MET ALA VAL ALA          
SEQRES   7 M  245  GLY LEU LEU ALA ASP ALA ARG SER LEU ALA ASP ILE ALA          
SEQRES   8 M  245  ARG GLU GLU ALA SER ASN PHE ARG SER ASN PHE GLY TYR          
SEQRES   9 M  245  ASN ILE PRO LEU LYS HIS LEU ALA ASP ARG VAL ALA MET          
SEQRES  10 M  245  TYR VAL HIS ALA TYR THR LEU TYR SER ALA VAL ARG PRO          
SEQRES  11 M  245  PHE GLY CYS SER PHE MET LEU GLY SER TYR SER VAL ASN          
SEQRES  12 M  245  ASP GLY ALA GLN LEU TYR MET ILE ASP PRO SER GLY VAL          
SEQRES  13 M  245  SER TYR GLY TYR TRP GLY CYS ALA ILE GLY LYS ALA ARG          
SEQRES  14 M  245  GLN ALA ALA LYS THR GLU ILE GLU LYS LEU GLN MET LYS          
SEQRES  15 M  245  GLU MET THR CYS ARG ASP ILE VAL LYS GLU VAL ALA LYS          
SEQRES  16 M  245  ILE ILE TYR ILE VAL HIS ASP GLU VAL LYS ASP LYS ALA          
SEQRES  17 M  245  PHE GLU LEU GLU LEU SER TRP VAL GLY GLU LEU THR ASN          
SEQRES  18 M  245  GLY ARG HIS GLU ILE VAL PRO LYS ASP ILE ARG GLU GLU          
SEQRES  19 M  245  ALA GLU LYS TYR ALA LYS GLU SER LEU LYS GLU                  
SEQRES   1 N  191  THR THR ILE MET ALA VAL GLN PHE ASP GLY GLY VAL VAL          
SEQRES   2 N  191  LEU GLY ALA ASP SER ARG THR THR THR GLY SER TYR ILE          
SEQRES   3 N  191  ALA ASN ARG VAL THR ASP LYS LEU THR PRO ILE HIS ASP          
SEQRES   4 N  191  ARG ILE PHE CYS CYS ARG SER GLY SER ALA ALA ASP THR          
SEQRES   5 N  191  GLN ALA VAL ALA ASP ALA VAL THR TYR GLN LEU GLY PHE          
SEQRES   6 N  191  HIS SER ILE GLU LEU ASN GLU PRO PRO LEU VAL HIS THR          
SEQRES   7 N  191  ALA ALA SER LEU PHE LYS GLU MET CYS TYR ARG TYR ARG          
SEQRES   8 N  191  GLU ASP LEU MET ALA GLY ILE ILE ILE ALA GLY TRP ASP          
SEQRES   9 N  191  PRO GLN GLU GLY GLY GLN VAL TYR SER VAL PRO MET GLY          
SEQRES  10 N  191  GLY MET MET VAL ARG GLN SER PHE ALA ILE GLY GLY SER          
SEQRES  11 N  191  GLY SER SER TYR ILE TYR GLY TYR VAL ASP ALA THR TYR          
SEQRES  12 N  191  ARG GLU GLY MET THR LYS GLU GLU CYS LEU GLN PHE THR          
SEQRES  13 N  191  ALA ASN ALA LEU ALA LEU ALA MET GLU ARG ASP GLY SER          
SEQRES  14 N  191  SER GLY GLY VAL ILE ARG LEU ALA ALA ILE ALA GLU SER          
SEQRES  15 N  191  GLY VAL GLU ARG GLN VAL LEU LEU GLY                          
SEQRES   1 O  220  THR THR ILE ALA GLY VAL VAL TYR LYS ASP GLY ILE VAL          
SEQRES   2 O  220  LEU GLY ALA ASP THR ARG ALA THR GLU GLY MET VAL VAL          
SEQRES   3 O  220  ALA ASP LYS ASN CYS SER LYS ILE HIS PHE ILE SER PRO          
SEQRES   4 O  220  ASN ILE TYR CYS CYS GLY ALA GLY THR ALA ALA ASP THR          
SEQRES   5 O  220  ASP MET THR THR GLN LEU ILE SER SER ASN LEU GLU LEU          
SEQRES   6 O  220  HIS SER LEU SER THR GLY ARG LEU PRO ARG VAL VAL THR          
SEQRES   7 O  220  ALA ASN ARG MET LEU LYS GLN MET LEU PHE ARG TYR GLN          
SEQRES   8 O  220  GLY TYR ILE GLY ALA ALA LEU VAL LEU GLY GLY VAL ASP          
SEQRES   9 O  220  VAL THR GLY PRO HIS LEU TYR SER ILE TYR PRO HIS GLY          
SEQRES  10 O  220  SER THR ASP LYS LEU PRO TYR VAL THR MET GLY SER GLY          
SEQRES  11 O  220  SER LEU ALA ALA MET ALA VAL PHE GLU ASP LYS PHE ARG          
SEQRES  12 O  220  PRO ASP MET GLU GLU GLU GLU ALA LYS ASN LEU VAL SER          
SEQRES  13 O  220  GLU ALA ILE ALA ALA GLY ILE PHE ASN ASP LEU GLY SER          
SEQRES  14 O  220  GLY SER ASN ILE ASP LEU CYS VAL ILE SER LYS ASN LYS          
SEQRES  15 O  220  LEU ASP PHE LEU ARG PRO TYR THR VAL PRO ASN LYS LYS          
SEQRES  16 O  220  GLY THR ARG LEU GLY ARG TYR ARG CYS GLU LYS GLY THR          
SEQRES  17 O  220  THR ALA VAL LEU THR GLU LYS ILE THR PRO LEU GLU              
SEQRES   1 P  204  SER ILE MET SER TYR ASN GLY GLY ALA VAL MET ALA MET          
SEQRES   2 P  204  LYS GLY LYS ASN CYS VAL ALA ILE ALA ALA ASP ARG ARG          
SEQRES   3 P  204  PHE GLY ILE GLN ALA GLN MET VAL THR THR ASP PHE GLN          
SEQRES   4 P  204  LYS ILE PHE PRO MET GLY ASP ARG LEU TYR ILE GLY LEU          
SEQRES   5 P  204  ALA GLY LEU ALA THR ASP VAL GLN THR VAL ALA GLN ARG          
SEQRES   6 P  204  LEU LYS PHE ARG LEU ASN LEU TYR GLU LEU LYS GLU GLY          
SEQRES   7 P  204  ARG GLN ILE LYS PRO TYR THR LEU MET SER MET VAL ALA          
SEQRES   8 P  204  ASN LEU LEU TYR GLU LYS ARG PHE GLY PRO TYR TYR THR          
SEQRES   9 P  204  GLU PRO VAL ILE ALA GLY LEU ASP PRO LYS THR PHE LYS          
SEQRES  10 P  204  PRO PHE ILE CYS SER LEU ASP LEU ILE GLY CYS PRO MET          
SEQRES  11 P  204  VAL THR ASP ASP PHE VAL VAL SER GLY THR CYS ALA GLU          
SEQRES  12 P  204  GLN MET TYR GLY MET CYS GLU SER LEU TRP GLU PRO ASN          
SEQRES  13 P  204  MET ASP PRO ASP HIS LEU PHE GLU THR ILE SER GLN ALA          
SEQRES  14 P  204  MET LEU ASN ALA VAL ASP ARG ASP ALA VAL SER GLY MET          
SEQRES  15 P  204  GLY VAL ILE VAL HIS ILE ILE GLU LYS ASP LYS ILE THR          
SEQRES  16 P  204  THR ARG THR LEU LYS ALA ARG MET ASP                          
SEQRES   1 Q  199  MET GLU TYR LEU ILE GLY ILE GLN GLY PRO ASP TYR VAL          
SEQRES   2 Q  199  LEU VAL ALA SER ASP ARG VAL ALA ALA SER ASN ILE VAL          
SEQRES   3 Q  199  GLN MET LYS ASP ASP HIS ASP LYS MET PHE LYS MET SER          
SEQRES   4 Q  199  GLU LYS ILE LEU LEU LEU CYS VAL GLY GLU ALA GLY ASP          
SEQRES   5 Q  199  THR VAL GLN PHE ALA GLU TYR ILE GLN LYS ASN VAL GLN          
SEQRES   6 Q  199  LEU TYR LYS MET ARG ASN GLY TYR GLU LEU SER PRO THR          
SEQRES   7 Q  199  ALA ALA ALA ASN PHE THR ARG ARG ASN LEU ALA ASP CYS          
SEQRES   8 Q  199  LEU ARG SER ARG THR PRO TYR HIS VAL ASN LEU LEU LEU          
SEQRES   9 Q  199  ALA GLY TYR ASP GLU HIS GLU GLY PRO ALA LEU TYR TYR          
SEQRES  10 Q  199  MET ASP TYR LEU ALA ALA LEU ALA LYS ALA PRO PHE ALA          
SEQRES  11 Q  199  ALA HIS GLY TYR GLY ALA PHE LEU THR LEU SER ILE LEU          
SEQRES  12 Q  199  ASP ARG TYR TYR THR PRO THR ILE SER ARG GLU ARG ALA          
SEQRES  13 Q  199  VAL GLU LEU LEU ARG LYS CYS LEU GLU GLU LEU GLN LYS          
SEQRES  14 Q  199  ARG PHE ILE LEU ASN LEU PRO THR PHE SER VAL ARG ILE          
SEQRES  15 Q  199  ILE ASP LYS ASN GLY ILE HIS ASP LEU ASP ASN ILE SER          
SEQRES  16 Q  199  PHE PRO LYS GLN                                              
SEQRES   1 R  201  THR THR THR LEU ALA PHE LYS PHE ARG HIS GLY VAL ILE          
SEQRES   2 R  201  VAL ALA ALA ASP SER ARG ALA THR ALA GLY ALA TYR ILE          
SEQRES   3 R  201  ALA SER GLN THR VAL LYS LYS VAL ILE GLU ILE ASN PRO          
SEQRES   4 R  201  TYR LEU LEU GLY THR MET ALA GLY GLY ALA ALA ASP CYS          
SEQRES   5 R  201  SER PHE TRP GLU ARG LEU LEU ALA ARG GLN CYS ARG ILE          
SEQRES   6 R  201  TYR GLU LEU ARG ASN LYS GLU ARG ILE SER VAL ALA ALA          
SEQRES   7 R  201  ALA SER LYS LEU LEU ALA ASN MET VAL TYR GLN TYR LYS          
SEQRES   8 R  201  GLY MET GLY LEU SER MET GLY THR MET ILE CYS GLY TRP          
SEQRES   9 R  201  ASP LYS ARG GLY PRO GLY LEU TYR TYR VAL ASP SER GLU          
SEQRES  10 R  201  GLY ASN ARG ILE SER GLY ALA THR PHE SER VAL GLY SER          
SEQRES  11 R  201  GLY SER VAL TYR ALA TYR GLY VAL MET ASP ARG GLY TYR          
SEQRES  12 R  201  SER TYR ASP LEU GLU VAL GLU GLN ALA TYR ASP LEU ALA          
SEQRES  13 R  201  ARG ARG ALA ILE TYR GLN ALA THR TYR ARG ASP ALA TYR          
SEQRES  14 R  201  SER GLY GLY ALA VAL ASN LEU TYR HIS VAL ARG GLU ASP          
SEQRES  15 R  201  GLY TRP ILE ARG VAL SER SER ASP ASN VAL ALA ASP LEU          
SEQRES  16 R  201  HIS GLU LYS TYR SER GLY                                      
SEQRES   1 S  213  ARG PHE SER PRO TYR VAL PHE ASN GLY GLY THR ILE LEU          
SEQRES   2 S  213  ALA ILE ALA GLY GLU ASP PHE ALA ILE VAL ALA SER ASP          
SEQRES   3 S  213  THR ARG LEU SER GLU GLY PHE SER ILE HIS THR ARG ASP          
SEQRES   4 S  213  SER PRO LYS CYS TYR LYS LEU THR ASP LYS THR VAL ILE          
SEQRES   5 S  213  GLY CYS SER GLY PHE HIS GLY ASP CYS LEU THR LEU THR          
SEQRES   6 S  213  LYS ILE ILE GLU ALA ARG LEU LYS MET TYR LYS HIS SER          
SEQRES   7 S  213  ASN ASN LYS ALA MET THR THR GLY ALA ILE ALA ALA MET          
SEQRES   8 S  213  LEU SER THR ILE LEU TYR SER ARG ARG PHE PHE PRO TYR          
SEQRES   9 S  213  TYR VAL TYR ASN ILE ILE GLY GLY LEU ASP GLU GLU GLY          
SEQRES  10 S  213  LYS GLY ALA VAL TYR SER PHE ASP PRO VAL GLY SER TYR          
SEQRES  11 S  213  GLN ARG ASP SER PHE LYS ALA GLY GLY SER ALA SER ALA          
SEQRES  12 S  213  MET LEU GLN PRO LEU LEU ASP ASN GLN VAL GLY PHE LYS          
SEQRES  13 S  213  ASN MET GLN ASN VAL GLU HIS VAL PRO LEU SER LEU ASP          
SEQRES  14 S  213  ARG ALA MET ARG LEU VAL LYS ASP VAL PHE ILE SER ALA          
SEQRES  15 S  213  ALA GLU ARG ASP VAL TYR THR GLY ASP ALA LEU ARG ILE          
SEQRES  16 S  213  CYS ILE VAL THR LYS GLU GLY ILE ARG GLU GLU THR VAL          
SEQRES  17 S  213  SER LEU ARG LYS ASP                                          
SEQRES   1 T  215  THR GLN ASN PRO MET VAL THR GLY THR SER VAL LEU GLY          
SEQRES   2 T  215  VAL LYS PHE GLU GLY GLY VAL VAL ILE ALA ALA ASP MET          
SEQRES   3 T  215  LEU GLY SER TYR GLY SER LEU ALA ARG PHE ARG ASN ILE          
SEQRES   4 T  215  SER ARG ILE MET ARG VAL ASN ASN SER THR MET LEU GLY          
SEQRES   5 T  215  ALA SER GLY ASP TYR ALA ASP PHE GLN TYR LEU LYS GLN          
SEQRES   6 T  215  VAL LEU GLY GLN MET VAL ILE ASP GLU GLU LEU LEU GLY          
SEQRES   7 T  215  ASP GLY HIS SER TYR SER PRO ARG ALA ILE HIS SER TRP          
SEQRES   8 T  215  LEU THR ARG ALA MET TYR SER ARG ARG SER LYS MET ASN          
SEQRES   9 T  215  PRO LEU TRP ASN THR MET VAL ILE GLY GLY TYR ALA ASP          
SEQRES  10 T  215  GLY GLU SER PHE LEU GLY TYR VAL ASP MET LEU GLY VAL          
SEQRES  11 T  215  ALA TYR GLU ALA PRO SER LEU ALA THR GLY TYR GLY ALA          
SEQRES  12 T  215  TYR LEU ALA GLN PRO LEU LEU ARG GLU VAL LEU GLU LYS          
SEQRES  13 T  215  GLN PRO VAL LEU SER GLN THR GLU ALA ARG ASP LEU VAL          
SEQRES  14 T  215  GLU ARG CYS MET ARG VAL LEU TYR TYR ARG ASP ALA ARG          
SEQRES  15 T  215  SER TYR ASN ARG PHE GLN ILE ALA THR VAL THR GLU LYS          
SEQRES  16 T  215  GLY VAL GLU ILE GLU GLY PRO LEU SER THR GLU THR ASN          
SEQRES  17 T  215  TRP ASP ILE ALA HIS MET ILE                                  
SEQRES   1 g  240  SER SER ALA GLY PHE ASP ARG HIS ILE THR ILE PHE SER          
SEQRES   2 g  240  PRO GLU GLY ARG LEU TYR GLN VAL GLU TYR ALA PHE LYS          
SEQRES   3 g  240  ALA ILE ASN GLN GLY GLY LEU THR SER VAL ALA VAL ARG          
SEQRES   4 g  240  GLY LYS ASP CYS ALA VAL ILE VAL THR GLN LYS LYS VAL          
SEQRES   5 g  240  PRO ASP LYS LEU LEU ASP SER SER THR VAL THR HIS LEU          
SEQRES   6 g  240  PHE LYS ILE THR GLU ASN ILE GLY CYS VAL MET THR GLY          
SEQRES   7 g  240  MET THR ALA ASP SER ARG SER GLN VAL GLN ARG ALA ARG          
SEQRES   8 g  240  TYR GLU ALA ALA ASN TRP LYS TYR LYS TYR GLY TYR GLU          
SEQRES   9 g  240  ILE PRO VAL ASP MET LEU CYS LYS ARG ILE ALA ASP ILE          
SEQRES  10 g  240  SER GLN VAL TYR THR GLN ASN ALA GLU MET ARG PRO LEU          
SEQRES  11 g  240  GLY CYS CYS MET ILE LEU ILE GLY ILE ASP GLU GLU GLN          
SEQRES  12 g  240  GLY PRO GLN VAL TYR LYS CYS ASP PRO ALA GLY TYR TYR          
SEQRES  13 g  240  CYS GLY PHE LYS ALA THR ALA ALA GLY VAL LYS GLN THR          
SEQRES  14 g  240  GLU SER THR SER PHE LEU GLU LYS LYS VAL LYS LYS LYS          
SEQRES  15 g  240  PHE ASP TRP THR PHE GLU GLN THR VAL GLU THR ALA ILE          
SEQRES  16 g  240  THR CYS LEU SER THR VAL LEU SER ILE ASP PHE LYS PRO          
SEQRES  17 g  240  SER GLU ILE GLU VAL GLY VAL VAL THR VAL GLU ASN PRO          
SEQRES  18 g  240  LYS PHE ARG ILE LEU THR GLU ALA GLU ILE ASP ALA HIS          
SEQRES  19 g  240  LEU VAL ALA LEU ALA GLU                                      
SEQRES   1 h  232  GLU ARG GLY TYR SER PHE SER LEU THR THR PHE SER PRO          
SEQRES   2 h  232  SER GLY LYS LEU VAL GLN ILE GLU TYR ALA LEU ALA ALA          
SEQRES   3 h  232  VAL ALA GLY GLY ALA PRO SER VAL GLY ILE LYS ALA ALA          
SEQRES   4 h  232  ASN GLY VAL VAL LEU ALA THR GLU LYS LYS GLN LYS SER          
SEQRES   5 h  232  ILE LEU TYR ASP GLU ARG SER VAL HIS LYS VAL GLU PRO          
SEQRES   6 h  232  ILE THR LYS HIS ILE GLY LEU VAL TYR SER GLY MET GLY          
SEQRES   7 h  232  PRO ASP TYR ARG VAL LEU VAL HIS ARG ALA ARG LYS LEU          
SEQRES   8 h  232  ALA GLN GLN TYR TYR LEU VAL TYR GLN GLU PRO ILE PRO          
SEQRES   9 h  232  THR ALA GLN LEU VAL GLN ARG VAL ALA SER VAL MET GLN          
SEQRES  10 h  232  GLU TYR THR GLN SER GLY GLY VAL ARG PRO PHE GLY VAL          
SEQRES  11 h  232  SER LEU LEU ILE CYS GLY TRP ASN GLU GLY ARG PRO TYR          
SEQRES  12 h  232  LEU PHE GLN SER ASP PRO SER GLY ALA TYR PHE ALA TRP          
SEQRES  13 h  232  LYS ALA THR ALA MET GLY LYS ASN TYR VAL ASN GLY LYS          
SEQRES  14 h  232  THR PHE LEU GLU LYS ARG TYR ASN GLU ASP LEU GLU LEU          
SEQRES  15 h  232  GLU ASP ALA ILE HIS THR ALA ILE LEU THR LEU LYS GLU          
SEQRES  16 h  232  SER PHE GLU GLY GLN MET THR GLU ASP ASN ILE GLU VAL          
SEQRES  17 h  232  GLY ILE CYS ASN GLU ALA GLY PHE ARG ARG LEU THR PRO          
SEQRES  18 h  232  THR GLU VAL LYS ASP TYR LEU ALA ALA ILE ALA                  
SEQRES   1 i  250  SER ARG ARG TYR ASP SER ARG THR THR ILE PHE SER PRO          
SEQRES   2 i  250  GLU GLY ARG LEU TYR GLN VAL GLU TYR ALA MET GLU ALA          
SEQRES   3 i  250  ILE GLY HIS ALA GLY THR CYS LEU GLY ILE LEU ALA ASN          
SEQRES   4 i  250  ASP GLY VAL LEU LEU ALA ALA GLU ARG ARG ASN ILE HIS          
SEQRES   5 i  250  LYS LEU LEU ASP GLU VAL PHE PHE SER GLU LYS ILE TYR          
SEQRES   6 i  250  LYS LEU ASN GLU ASP MET ALA CYS SER VAL ALA GLY ILE          
SEQRES   7 i  250  THR SER ASP ALA ASN VAL LEU THR ASN GLU LEU ARG LEU          
SEQRES   8 i  250  ILE ALA GLN ARG TYR LEU LEU GLN TYR GLN GLU PRO ILE          
SEQRES   9 i  250  PRO CYS GLU GLN LEU VAL THR ALA LEU CYS ASP ILE LYS          
SEQRES  10 i  250  GLN ALA TYR THR GLN PHE GLY GLY LYS ARG PRO PHE GLY          
SEQRES  11 i  250  VAL SER LEU LEU TYR ILE GLY TRP ASP LYS HIS TYR GLY          
SEQRES  12 i  250  PHE GLN LEU TYR GLN SER ASP PRO SER GLY ASN TYR GLY          
SEQRES  13 i  250  GLY TRP LYS ALA THR CYS ILE GLY ASN ASN SER ALA ALA          
SEQRES  14 i  250  ALA VAL SER MET LEU LYS GLN ASP TYR LYS GLU GLY GLU          
SEQRES  15 i  250  MET THR LEU LYS SER ALA LEU ALA LEU ALA ILE LYS VAL          
SEQRES  16 i  250  LEU ASN LYS THR MET ASP VAL SER LYS LEU SER ALA GLU          
SEQRES  17 i  250  LYS VAL GLU ILE ALA THR LEU THR ARG GLU ASN GLY LYS          
SEQRES  18 i  250  THR VAL ILE ARG VAL LEU LYS GLN LYS GLU VAL GLU GLN          
SEQRES  19 i  250  LEU ILE LYS LYS HIS GLU GLU GLU GLU ALA LYS ALA GLU          
SEQRES  20 i  250  ARG GLU LYS                                                  
SEQRES   1 j  243  SER TYR ASP ARG ALA ILE THR VAL PHE SER PRO ASP GLY          
SEQRES   2 j  243  HIS LEU PHE GLN VAL GLU TYR ALA GLN GLU ALA VAL LYS          
SEQRES   3 j  243  LYS GLY SER THR ALA VAL GLY VAL ARG GLY ARG ASP ILE          
SEQRES   4 j  243  VAL VAL LEU GLY VAL GLU LYS LYS SER VAL ALA LYS LEU          
SEQRES   5 j  243  GLN ASP GLU ARG THR VAL ARG LYS ILE CYS ALA LEU ASP          
SEQRES   6 j  243  ASP ASN VAL CYS MET ALA PHE ALA GLY LEU THR ALA ASP          
SEQRES   7 j  243  ALA ARG ILE VAL ILE ASN ARG ALA ARG VAL GLU CYS GLN          
SEQRES   8 j  243  SER HIS ARG LEU THR VAL GLU ASP PRO VAL THR VAL GLU          
SEQRES   9 j  243  TYR ILE THR ARG TYR ILE ALA SER LEU LYS GLN ARG TYR          
SEQRES  10 j  243  THR GLN SER ASN GLY ARG ARG PRO PHE GLY ILE SER ALA          
SEQRES  11 j  243  LEU ILE VAL GLY PHE ASP PHE ASP GLY THR PRO ARG LEU          
SEQRES  12 j  243  TYR GLN THR ASP PRO SER GLY THR TYR HIS ALA TRP LYS          
SEQRES  13 j  243  ALA ASN ALA ILE GLY ARG GLY ALA LYS SER VAL ARG GLU          
SEQRES  14 j  243  PHE LEU GLU LYS ASN TYR THR ASP GLU ALA ILE GLU THR          
SEQRES  15 j  243  ASP ASP LEU THR ILE LYS LEU VAL ILE LYS ALA LEU LEU          
SEQRES  16 j  243  GLU VAL VAL GLN SER GLY GLY LYS ASN ILE GLU LEU ALA          
SEQRES  17 j  243  VAL MET ARG ARG ASP GLN SER LEU LYS ILE LEU ASN PRO          
SEQRES  18 j  243  GLU GLU ILE GLU LYS TYR VAL ALA GLU ILE GLU LYS GLU          
SEQRES  19 j  243  LYS GLU GLU ASN GLU LYS LYS LYS GLN                          
SEQRES   1 k  234  TYR ASP ARG GLY VAL ASN THR PHE SER PRO GLU GLY ARG          
SEQRES   2 k  234  LEU PHE GLN VAL GLU TYR ALA ILE GLU ALA ILE LYS LEU          
SEQRES   3 k  234  GLY SER THR ALA ILE GLY ILE GLN THR SER GLU GLY VAL          
SEQRES   4 k  234  CYS LEU ALA VAL GLU LYS ARG ILE THR SER PRO LEU MET          
SEQRES   5 k  234  GLU PRO SER SER ILE GLU LYS ILE VAL GLU ILE ASP ALA          
SEQRES   6 k  234  HIS ILE GLY CYS ALA MET SER GLY LEU ILE ALA ASP ALA          
SEQRES   7 k  234  LYS THR LEU ILE ASP LYS ALA ARG VAL GLU THR GLN ASN          
SEQRES   8 k  234  HIS TRP PHE THR TYR ASN GLU THR MET THR VAL GLU SER          
SEQRES   9 k  234  VAL THR GLN ALA VAL SER ASN LEU ALA LEU GLN PHE GLY          
SEQRES  10 k  234  GLU GLU ASP ALA ASP PRO GLY ALA MET SER ARG PRO PHE          
SEQRES  11 k  234  GLY VAL ALA LEU LEU PHE GLY GLY VAL ASP GLU LYS GLY          
SEQRES  12 k  234  PRO GLN LEU PHE HIS MET ASP PRO SER GLY THR PHE VAL          
SEQRES  13 k  234  GLN CYS ASP ALA ARG ALA ILE GLY SER ALA SER GLU GLY          
SEQRES  14 k  234  ALA GLN SER SER LEU GLN GLU VAL TYR HIS LYS SER MET          
SEQRES  15 k  234  THR LEU LYS GLU ALA ILE LYS SER SER LEU ILE ILE LEU          
SEQRES  16 k  234  LYS GLN VAL MET GLU GLU LYS LEU ASN ALA THR ASN ILE          
SEQRES  17 k  234  GLU LEU ALA THR VAL GLN PRO GLY GLN ASN PHE HIS MET          
SEQRES  18 k  234  PHE THR LYS GLU GLU LEU GLU GLU VAL ILE LYS ASP ILE          
SEQRES   1 l  238  ASN GLN TYR ASP ASN ASP VAL THR VAL TRP SER PRO GLN          
SEQRES   2 l  238  GLY ARG ILE HIS GLN ILE GLU TYR ALA MET GLU ALA VAL          
SEQRES   3 l  238  LYS GLN GLY SER ALA THR VAL GLY LEU LYS SER LYS THR          
SEQRES   4 l  238  HIS ALA VAL LEU VAL ALA LEU LYS ARG ALA GLN SER GLU          
SEQRES   5 l  238  LEU ALA ALA HIS GLN LYS LYS ILE LEU HIS VAL ASP ASN          
SEQRES   6 l  238  HIS ILE GLY ILE SER ILE ALA GLY LEU THR ALA ASP ALA          
SEQRES   7 l  238  ARG LEU LEU CYS ASN PHE MET ARG GLN GLU CYS LEU ASP          
SEQRES   8 l  238  SER ARG PHE VAL PHE ASP ARG PRO LEU PRO VAL SER ARG          
SEQRES   9 l  238  LEU VAL SER LEU ILE GLY SER LYS THR GLN ILE PRO THR          
SEQRES  10 l  238  GLN ARG TYR GLY ARG ARG PRO TYR GLY VAL GLY LEU LEU          
SEQRES  11 l  238  ILE ALA GLY TYR ASP ASP MET GLY PRO HIS ILE PHE GLN          
SEQRES  12 l  238  THR CYS PRO SER ALA ASN TYR PHE ASP CYS ARG ALA MET          
SEQRES  13 l  238  SER ILE GLY ALA ARG SER GLN SER ALA ARG THR TYR LEU          
SEQRES  14 l  238  GLU ARG HIS MET SER GLU PHE MET GLU CYS ASN LEU ASN          
SEQRES  15 l  238  GLU LEU VAL LYS HIS GLY LEU ARG ALA LEU ARG GLU THR          
SEQRES  16 l  238  LEU PRO ALA GLU GLN ASP LEU THR THR LYS ASN VAL SER          
SEQRES  17 l  238  ILE GLY ILE VAL GLY LYS ASP LEU GLU PHE THR ILE TYR          
SEQRES  18 l  238  ASP ASP ASP ASP VAL SER PRO PHE LEU GLU GLY LEU GLU          
SEQRES  19 l  238  GLU ARG PRO GLN                                              
SEQRES   1 m  245  SER SER ILE GLY THR GLY TYR ASP LEU SER ALA SER THR          
SEQRES   2 m  245  PHE SER PRO ASP GLY ARG VAL PHE GLN VAL GLU TYR ALA          
SEQRES   3 m  245  MET LYS ALA VAL GLU ASN SER SER THR ALA ILE GLY ILE          
SEQRES   4 m  245  ARG CYS LYS ASP GLY VAL VAL PHE GLY VAL GLU LYS LEU          
SEQRES   5 m  245  VAL LEU SER LYS LEU TYR GLU GLU GLY SER ASN LYS ARG          
SEQRES   6 m  245  LEU PHE ASN VAL ASP ARG HIS VAL GLY MET ALA VAL ALA          
SEQRES   7 m  245  GLY LEU LEU ALA ASP ALA ARG SER LEU ALA ASP ILE ALA          
SEQRES   8 m  245  ARG GLU GLU ALA SER ASN PHE ARG SER ASN PHE GLY TYR          
SEQRES   9 m  245  ASN ILE PRO LEU LYS HIS LEU ALA ASP ARG VAL ALA MET          
SEQRES  10 m  245  TYR VAL HIS ALA TYR THR LEU TYR SER ALA VAL ARG PRO          
SEQRES  11 m  245  PHE GLY CYS SER PHE MET LEU GLY SER TYR SER VAL ASN          
SEQRES  12 m  245  ASP GLY ALA GLN LEU TYR MET ILE ASP PRO SER GLY VAL          
SEQRES  13 m  245  SER TYR GLY TYR TRP GLY CYS ALA ILE GLY LYS ALA ARG          
SEQRES  14 m  245  GLN ALA ALA LYS THR GLU ILE GLU LYS LEU GLN MET LYS          
SEQRES  15 m  245  GLU MET THR CYS ARG ASP ILE VAL LYS GLU VAL ALA LYS          
SEQRES  16 m  245  ILE ILE TYR ILE VAL HIS ASP GLU VAL LYS ASP LYS ALA          
SEQRES  17 m  245  PHE GLU LEU GLU LEU SER TRP VAL GLY GLU LEU THR ASN          
SEQRES  18 m  245  GLY ARG HIS GLU ILE VAL PRO LYS ASP ILE ARG GLU GLU          
SEQRES  19 m  245  ALA GLU LYS TYR ALA LYS GLU SER LEU LYS GLU                  
SEQRES   1 n  191  THR THR ILE MET ALA VAL GLN PHE ASP GLY GLY VAL VAL          
SEQRES   2 n  191  LEU GLY ALA ASP SER ARG THR THR THR GLY SER TYR ILE          
SEQRES   3 n  191  ALA ASN ARG VAL THR ASP LYS LEU THR PRO ILE HIS ASP          
SEQRES   4 n  191  ARG ILE PHE CYS CYS ARG SER GLY SER ALA ALA ASP THR          
SEQRES   5 n  191  GLN ALA VAL ALA ASP ALA VAL THR TYR GLN LEU GLY PHE          
SEQRES   6 n  191  HIS SER ILE GLU LEU ASN GLU PRO PRO LEU VAL HIS THR          
SEQRES   7 n  191  ALA ALA SER LEU PHE LYS GLU MET CYS TYR ARG TYR ARG          
SEQRES   8 n  191  GLU ASP LEU MET ALA GLY ILE ILE ILE ALA GLY TRP ASP          
SEQRES   9 n  191  PRO GLN GLU GLY GLY GLN VAL TYR SER VAL PRO MET GLY          
SEQRES  10 n  191  GLY MET MET VAL ARG GLN SER PHE ALA ILE GLY GLY SER          
SEQRES  11 n  191  GLY SER SER TYR ILE TYR GLY TYR VAL ASP ALA THR TYR          
SEQRES  12 n  191  ARG GLU GLY MET THR LYS GLU GLU CYS LEU GLN PHE THR          
SEQRES  13 n  191  ALA ASN ALA LEU ALA LEU ALA MET GLU ARG ASP GLY SER          
SEQRES  14 n  191  SER GLY GLY VAL ILE ARG LEU ALA ALA ILE ALA GLU SER          
SEQRES  15 n  191  GLY VAL GLU ARG GLN VAL LEU LEU GLY                          
SEQRES   1 o  220  THR THR ILE ALA GLY VAL VAL TYR LYS ASP GLY ILE VAL          
SEQRES   2 o  220  LEU GLY ALA ASP THR ARG ALA THR GLU GLY MET VAL VAL          
SEQRES   3 o  220  ALA ASP LYS ASN CYS SER LYS ILE HIS PHE ILE SER PRO          
SEQRES   4 o  220  ASN ILE TYR CYS CYS GLY ALA GLY THR ALA ALA ASP THR          
SEQRES   5 o  220  ASP MET THR THR GLN LEU ILE SER SER ASN LEU GLU LEU          
SEQRES   6 o  220  HIS SER LEU SER THR GLY ARG LEU PRO ARG VAL VAL THR          
SEQRES   7 o  220  ALA ASN ARG MET LEU LYS GLN MET LEU PHE ARG TYR GLN          
SEQRES   8 o  220  GLY TYR ILE GLY ALA ALA LEU VAL LEU GLY GLY VAL ASP          
SEQRES   9 o  220  VAL THR GLY PRO HIS LEU TYR SER ILE TYR PRO HIS GLY          
SEQRES  10 o  220  SER THR ASP LYS LEU PRO TYR VAL THR MET GLY SER GLY          
SEQRES  11 o  220  SER LEU ALA ALA MET ALA VAL PHE GLU ASP LYS PHE ARG          
SEQRES  12 o  220  PRO ASP MET GLU GLU GLU GLU ALA LYS ASN LEU VAL SER          
SEQRES  13 o  220  GLU ALA ILE ALA ALA GLY ILE PHE ASN ASP LEU GLY SER          
SEQRES  14 o  220  GLY SER ASN ILE ASP LEU CYS VAL ILE SER LYS ASN LYS          
SEQRES  15 o  220  LEU ASP PHE LEU ARG PRO TYR THR VAL PRO ASN LYS LYS          
SEQRES  16 o  220  GLY THR ARG LEU GLY ARG TYR ARG CYS GLU LYS GLY THR          
SEQRES  17 o  220  THR ALA VAL LEU THR GLU LYS ILE THR PRO LEU GLU              
SEQRES   1 p  204  SER ILE MET SER TYR ASN GLY GLY ALA VAL MET ALA MET          
SEQRES   2 p  204  LYS GLY LYS ASN CYS VAL ALA ILE ALA ALA ASP ARG ARG          
SEQRES   3 p  204  PHE GLY ILE GLN ALA GLN MET VAL THR THR ASP PHE GLN          
SEQRES   4 p  204  LYS ILE PHE PRO MET GLY ASP ARG LEU TYR ILE GLY LEU          
SEQRES   5 p  204  ALA GLY LEU ALA THR ASP VAL GLN THR VAL ALA GLN ARG          
SEQRES   6 p  204  LEU LYS PHE ARG LEU ASN LEU TYR GLU LEU LYS GLU GLY          
SEQRES   7 p  204  ARG GLN ILE LYS PRO TYR THR LEU MET SER MET VAL ALA          
SEQRES   8 p  204  ASN LEU LEU TYR GLU LYS ARG PHE GLY PRO TYR TYR THR          
SEQRES   9 p  204  GLU PRO VAL ILE ALA GLY LEU ASP PRO LYS THR PHE LYS          
SEQRES  10 p  204  PRO PHE ILE CYS SER LEU ASP LEU ILE GLY CYS PRO MET          
SEQRES  11 p  204  VAL THR ASP ASP PHE VAL VAL SER GLY THR CYS ALA GLU          
SEQRES  12 p  204  GLN MET TYR GLY MET CYS GLU SER LEU TRP GLU PRO ASN          
SEQRES  13 p  204  MET ASP PRO ASP HIS LEU PHE GLU THR ILE SER GLN ALA          
SEQRES  14 p  204  MET LEU ASN ALA VAL ASP ARG ASP ALA VAL SER GLY MET          
SEQRES  15 p  204  GLY VAL ILE VAL HIS ILE ILE GLU LYS ASP LYS ILE THR          
SEQRES  16 p  204  THR ARG THR LEU LYS ALA ARG MET ASP                          
SEQRES   1 q  199  MET GLU TYR LEU ILE GLY ILE GLN GLY PRO ASP TYR VAL          
SEQRES   2 q  199  LEU VAL ALA SER ASP ARG VAL ALA ALA SER ASN ILE VAL          
SEQRES   3 q  199  GLN MET LYS ASP ASP HIS ASP LYS MET PHE LYS MET SER          
SEQRES   4 q  199  GLU LYS ILE LEU LEU LEU CYS VAL GLY GLU ALA GLY ASP          
SEQRES   5 q  199  THR VAL GLN PHE ALA GLU TYR ILE GLN LYS ASN VAL GLN          
SEQRES   6 q  199  LEU TYR LYS MET ARG ASN GLY TYR GLU LEU SER PRO THR          
SEQRES   7 q  199  ALA ALA ALA ASN PHE THR ARG ARG ASN LEU ALA ASP CYS          
SEQRES   8 q  199  LEU ARG SER ARG THR PRO TYR HIS VAL ASN LEU LEU LEU          
SEQRES   9 q  199  ALA GLY TYR ASP GLU HIS GLU GLY PRO ALA LEU TYR TYR          
SEQRES  10 q  199  MET ASP TYR LEU ALA ALA LEU ALA LYS ALA PRO PHE ALA          
SEQRES  11 q  199  ALA HIS GLY TYR GLY ALA PHE LEU THR LEU SER ILE LEU          
SEQRES  12 q  199  ASP ARG TYR TYR THR PRO THR ILE SER ARG GLU ARG ALA          
SEQRES  13 q  199  VAL GLU LEU LEU ARG LYS CYS LEU GLU GLU LEU GLN LYS          
SEQRES  14 q  199  ARG PHE ILE LEU ASN LEU PRO THR PHE SER VAL ARG ILE          
SEQRES  15 q  199  ILE ASP LYS ASN GLY ILE HIS ASP LEU ASP ASN ILE SER          
SEQRES  16 q  199  PHE PRO LYS GLN                                              
SEQRES   1 r  201  THR THR THR LEU ALA PHE LYS PHE ARG HIS GLY VAL ILE          
SEQRES   2 r  201  VAL ALA ALA ASP SER ARG ALA THR ALA GLY ALA TYR ILE          
SEQRES   3 r  201  ALA SER GLN THR VAL LYS LYS VAL ILE GLU ILE ASN PRO          
SEQRES   4 r  201  TYR LEU LEU GLY THR MET ALA GLY GLY ALA ALA ASP CYS          
SEQRES   5 r  201  SER PHE TRP GLU ARG LEU LEU ALA ARG GLN CYS ARG ILE          
SEQRES   6 r  201  TYR GLU LEU ARG ASN LYS GLU ARG ILE SER VAL ALA ALA          
SEQRES   7 r  201  ALA SER LYS LEU LEU ALA ASN MET VAL TYR GLN TYR LYS          
SEQRES   8 r  201  GLY MET GLY LEU SER MET GLY THR MET ILE CYS GLY TRP          
SEQRES   9 r  201  ASP LYS ARG GLY PRO GLY LEU TYR TYR VAL ASP SER GLU          
SEQRES  10 r  201  GLY ASN ARG ILE SER GLY ALA THR PHE SER VAL GLY SER          
SEQRES  11 r  201  GLY SER VAL TYR ALA TYR GLY VAL MET ASP ARG GLY TYR          
SEQRES  12 r  201  SER TYR ASP LEU GLU VAL GLU GLN ALA TYR ASP LEU ALA          
SEQRES  13 r  201  ARG ARG ALA ILE TYR GLN ALA THR TYR ARG ASP ALA TYR          
SEQRES  14 r  201  SER GLY GLY ALA VAL ASN LEU TYR HIS VAL ARG GLU ASP          
SEQRES  15 r  201  GLY TRP ILE ARG VAL SER SER ASP ASN VAL ALA ASP LEU          
SEQRES  16 r  201  HIS GLU LYS TYR SER GLY                                      
SEQRES   1 s  213  ARG PHE SER PRO TYR VAL PHE ASN GLY GLY THR ILE LEU          
SEQRES   2 s  213  ALA ILE ALA GLY GLU ASP PHE ALA ILE VAL ALA SER ASP          
SEQRES   3 s  213  THR ARG LEU SER GLU GLY PHE SER ILE HIS THR ARG ASP          
SEQRES   4 s  213  SER PRO LYS CYS TYR LYS LEU THR ASP LYS THR VAL ILE          
SEQRES   5 s  213  GLY CYS SER GLY PHE HIS GLY ASP CYS LEU THR LEU THR          
SEQRES   6 s  213  LYS ILE ILE GLU ALA ARG LEU LYS MET TYR LYS HIS SER          
SEQRES   7 s  213  ASN ASN LYS ALA MET THR THR GLY ALA ILE ALA ALA MET          
SEQRES   8 s  213  LEU SER THR ILE LEU TYR SER ARG ARG PHE PHE PRO TYR          
SEQRES   9 s  213  TYR VAL TYR ASN ILE ILE GLY GLY LEU ASP GLU GLU GLY          
SEQRES  10 s  213  LYS GLY ALA VAL TYR SER PHE ASP PRO VAL GLY SER TYR          
SEQRES  11 s  213  GLN ARG ASP SER PHE LYS ALA GLY GLY SER ALA SER ALA          
SEQRES  12 s  213  MET LEU GLN PRO LEU LEU ASP ASN GLN VAL GLY PHE LYS          
SEQRES  13 s  213  ASN MET GLN ASN VAL GLU HIS VAL PRO LEU SER LEU ASP          
SEQRES  14 s  213  ARG ALA MET ARG LEU VAL LYS ASP VAL PHE ILE SER ALA          
SEQRES  15 s  213  ALA GLU ARG ASP VAL TYR THR GLY ASP ALA LEU ARG ILE          
SEQRES  16 s  213  CYS ILE VAL THR LYS GLU GLY ILE ARG GLU GLU THR VAL          
SEQRES  17 s  213  SER LEU ARG LYS ASP                                          
SEQRES   1 t  215  THR GLN ASN PRO MET VAL THR GLY THR SER VAL LEU GLY          
SEQRES   2 t  215  VAL LYS PHE GLU GLY GLY VAL VAL ILE ALA ALA ASP MET          
SEQRES   3 t  215  LEU GLY SER TYR GLY SER LEU ALA ARG PHE ARG ASN ILE          
SEQRES   4 t  215  SER ARG ILE MET ARG VAL ASN ASN SER THR MET LEU GLY          
SEQRES   5 t  215  ALA SER GLY ASP TYR ALA ASP PHE GLN TYR LEU LYS GLN          
SEQRES   6 t  215  VAL LEU GLY GLN MET VAL ILE ASP GLU GLU LEU LEU GLY          
SEQRES   7 t  215  ASP GLY HIS SER TYR SER PRO ARG ALA ILE HIS SER TRP          
SEQRES   8 t  215  LEU THR ARG ALA MET TYR SER ARG ARG SER LYS MET ASN          
SEQRES   9 t  215  PRO LEU TRP ASN THR MET VAL ILE GLY GLY TYR ALA ASP          
SEQRES  10 t  215  GLY GLU SER PHE LEU GLY TYR VAL ASP MET LEU GLY VAL          
SEQRES  11 t  215  ALA TYR GLU ALA PRO SER LEU ALA THR GLY TYR GLY ALA          
SEQRES  12 t  215  TYR LEU ALA GLN PRO LEU LEU ARG GLU VAL LEU GLU LYS          
SEQRES  13 t  215  GLN PRO VAL LEU SER GLN THR GLU ALA ARG ASP LEU VAL          
SEQRES  14 t  215  GLU ARG CYS MET ARG VAL LEU TYR TYR ARG ASP ALA ARG          
SEQRES  15 t  215  SER TYR ASN ARG PHE GLN ILE ALA THR VAL THR GLU LYS          
SEQRES  16 t  215  GLY VAL GLU ILE GLU GLY PRO LEU SER THR GLU THR ASN          
SEQRES  17 t  215  TRP ASP ILE ALA HIS MET ILE                                  
SEQRES   1 f  908  MET GLU GLU GLY GLY ARG ASP LYS ALA PRO VAL GLN PRO          
SEQRES   2 f  908  GLN GLN SER PRO ALA ALA ALA PRO GLY GLY THR ASP GLU          
SEQRES   3 f  908  LYS PRO SER GLY LYS GLU ARG ARG ASP ALA GLY ASP LYS          
SEQRES   4 f  908  ASP LYS GLU GLN GLU LEU SER GLU GLU ASP LYS GLN LEU          
SEQRES   5 f  908  GLN ASP GLU LEU GLU MET LEU VAL GLU ARG LEU GLY GLU          
SEQRES   6 f  908  LYS ASP THR SER LEU TYR ARG PRO ALA LEU GLU GLU LEU          
SEQRES   7 f  908  ARG ARG GLN ILE ARG SER SER THR THR SER MET THR SER          
SEQRES   8 f  908  VAL PRO LYS PRO LEU LYS PHE LEU ARG PRO HIS TYR GLY          
SEQRES   9 f  908  LYS LEU LYS GLU ILE TYR GLU ASN MET ALA PRO GLY GLU          
SEQRES  10 f  908  ASN LYS ARG PHE ALA ALA ASP ILE ILE SER VAL LEU ALA          
SEQRES  11 f  908  MET THR MET SER GLY GLU ARG GLU CYS LEU LYS TYR ARG          
SEQRES  12 f  908  LEU VAL GLY SER GLN GLU GLU LEU ALA SER TRP GLY HIS          
SEQRES  13 f  908  GLU TYR VAL ARG HIS LEU ALA GLY GLU VAL ALA LYS GLU          
SEQRES  14 f  908  TRP GLN GLU LEU ASP ASP ALA GLU LYS VAL GLN ARG GLU          
SEQRES  15 f  908  PRO LEU LEU THR LEU VAL LYS GLU ILE VAL PRO TYR ASN          
SEQRES  16 f  908  MET ALA HIS ASN ALA GLU HIS GLU ALA CYS ASP LEU LEU          
SEQRES  17 f  908  MET GLU ILE GLU GLN VAL ASP MET LEU GLU LYS ASP ILE          
SEQRES  18 f  908  ASP GLU ASN ALA TYR ALA LYS VAL CYS LEU TYR LEU THR          
SEQRES  19 f  908  SER CYS VAL ASN TYR VAL PRO GLU PRO GLU ASN SER ALA          
SEQRES  20 f  908  LEU LEU ARG CYS ALA LEU GLY VAL PHE ARG LYS PHE SER          
SEQRES  21 f  908  ARG PHE PRO GLU ALA LEU ARG LEU ALA LEU MET LEU ASN          
SEQRES  22 f  908  ASP MET GLU LEU VAL GLU ASP ILE PHE THR SER CYS LYS          
SEQRES  23 f  908  ASP VAL VAL VAL GLN LYS GLN MET ALA PHE MET LEU GLY          
SEQRES  24 f  908  ARG HIS GLY VAL PHE LEU GLU LEU SER GLU ASP VAL GLU          
SEQRES  25 f  908  GLU TYR GLU ASP LEU THR GLU ILE MET SER ASN VAL GLN          
SEQRES  26 f  908  LEU ASN SER ASN PHE LEU ALA LEU ALA ARG GLU LEU ASP          
SEQRES  27 f  908  ILE MET GLU PRO LYS VAL PRO ASP ASP ILE TYR LYS THR          
SEQRES  28 f  908  HIS LEU GLU ASN ASN ARG PHE GLY GLY SER GLY SER GLN          
SEQRES  29 f  908  VAL ASP SER ALA ARG MET ASN LEU ALA SER SER PHE VAL          
SEQRES  30 f  908  ASN GLY PHE VAL ASN ALA ALA PHE GLY GLN ASP LYS LEU          
SEQRES  31 f  908  LEU THR ASP ASP GLY ASN LYS TRP LEU TYR LYS ASN LYS          
SEQRES  32 f  908  ASP HIS GLY MET LEU SER ALA ALA ALA SER LEU GLY MET          
SEQRES  33 f  908  ILE LEU LEU TRP ASP VAL ASP GLY GLY LEU THR GLN ILE          
SEQRES  34 f  908  ASP LYS TYR LEU TYR SER SER GLU ASP TYR ILE LYS SER          
SEQRES  35 f  908  GLY ALA LEU LEU ALA CYS GLY ILE VAL ASN SER GLY VAL          
SEQRES  36 f  908  ARG ASN GLU CYS ASP PRO ALA LEU ALA LEU LEU SER ASP          
SEQRES  37 f  908  TYR VAL LEU HIS ASN SER ASN THR MET ARG LEU GLY SER          
SEQRES  38 f  908  ILE PHE GLY LEU GLY LEU ALA TYR ALA GLY SER ASN ARG          
SEQRES  39 f  908  GLU ASP VAL LEU THR LEU LEU LEU PRO VAL MET GLY ASP          
SEQRES  40 f  908  SER LYS SER SER MET GLU VAL ALA GLY VAL THR ALA LEU          
SEQRES  41 f  908  ALA CYS GLY MET ILE ALA VAL GLY SER CYS ASN GLY ASP          
SEQRES  42 f  908  VAL THR SER THR ILE LEU GLN THR ILE MET GLU LYS SER          
SEQRES  43 f  908  GLU THR GLU LEU LYS ASP THR TYR ALA ARG TRP LEU PRO          
SEQRES  44 f  908  LEU GLY LEU GLY LEU ASN HIS LEU GLY LYS GLY GLU ALA          
SEQRES  45 f  908  ILE GLU ALA ILE LEU ALA ALA LEU GLU VAL VAL SER GLU          
SEQRES  46 f  908  PRO PHE ARG SER PHE ALA ASN THR LEU VAL ASP VAL CYS          
SEQRES  47 f  908  ALA TYR ALA GLY SER GLY ASN VAL LEU LYS VAL GLN GLN          
SEQRES  48 f  908  LEU LEU HIS ILE CYS SER GLU HIS PHE ASP SER LYS GLU          
SEQRES  49 f  908  LYS GLU GLU ASP LYS ASP LYS LYS GLU LYS LYS ASP LYS          
SEQRES  50 f  908  ASP LYS LYS GLU ALA PRO ALA ASP MET GLY ALA HIS GLN          
SEQRES  51 f  908  GLY VAL ALA VAL LEU GLY ILE ALA LEU ILE ALA MET GLY          
SEQRES  52 f  908  GLU GLU ILE GLY ALA GLU MET ALA LEU ARG THR PHE GLY          
SEQRES  53 f  908  HIS LEU LEU ARG TYR GLY GLU PRO THR LEU ARG ARG ALA          
SEQRES  54 f  908  VAL PRO LEU ALA LEU ALA LEU ILE SER VAL SER ASN PRO          
SEQRES  55 f  908  ARG LEU ASN ILE LEU ASP THR LEU SER LYS PHE SER HIS          
SEQRES  56 f  908  ASP ALA ASP PRO GLU VAL SER TYR ASN SER ILE PHE ALA          
SEQRES  57 f  908  MET GLY MET VAL GLY SER GLY THR ASN ASN ALA ARG LEU          
SEQRES  58 f  908  ALA ALA MET LEU ARG GLN LEU ALA GLN TYR HIS ALA LYS          
SEQRES  59 f  908  ASP PRO ASN ASN LEU PHE MET VAL ARG LEU ALA GLN GLY          
SEQRES  60 f  908  LEU THR HIS LEU GLY LYS GLY THR LEU THR LEU CYS PRO          
SEQRES  61 f  908  TYR HIS SER ASP ARG GLN LEU MET SER GLN VAL ALA VAL          
SEQRES  62 f  908  ALA GLY LEU LEU THR VAL LEU VAL SER PHE LEU ASP VAL          
SEQRES  63 f  908  ARG ASN ILE ILE LEU GLY LYS SER HIS TYR VAL LEU TYR          
SEQRES  64 f  908  GLY LEU VAL ALA ALA MET GLN PRO ARG MET LEU VAL THR          
SEQRES  65 f  908  PHE ASP GLU GLU LEU ARG PRO LEU PRO VAL SER VAL ARG          
SEQRES  66 f  908  VAL GLY GLN ALA VAL ASP VAL VAL GLY GLN ALA GLY LYS          
SEQRES  67 f  908  PRO LYS THR ILE THR GLY PHE GLN THR HIS THR THR PRO          
SEQRES  68 f  908  VAL LEU LEU ALA HIS GLY GLU ARG ALA GLU LEU ALA THR          
SEQRES  69 f  908  GLU GLU PHE LEU PRO VAL THR PRO ILE LEU GLU GLY PHE          
SEQRES  70 f  908  VAL ILE LEU ARG LYS ASN PRO ASN TYR ASP LEU                  
HET     ZN  c 401       1                                                       
HETNAM      ZN ZINC ION                                                         
FORMUL  47   ZN    ZN 2+                                                        
HELIX    1 AA1 GLY U    7  GLU U   14  5                                   8    
HELIX    2 AA2 PRO U   17  TRP U   35  1                                  19    
HELIX    3 AA3 SER U   41  GLU U   50  1                                  10    
HELIX    4 AA4 SER U   56  GLY U   72  1                                  17    
HELIX    5 AA5 PHE U   74  GLY U   83  1                                  10    
HELIX    6 AA6 GLY U   85  VAL U   90  1                                   6    
HELIX    7 AA7 TYR U   96  ASP U  117  1                                  22    
HELIX    8 AA8 ASP U  127  ASP U  144  1                                  18    
HELIX    9 AA9 LYS U  146  THR U  157  1                                  12    
HELIX   10 AB1 ARG U  159  ILE U  167  1                                   9    
HELIX   11 AB2 GLY U  175  MET U  188  1                                  14    
HELIX   12 AB3 ASN U  190  ASN U  207  1                                  18    
HELIX   13 AB4 ASP U  212  ILE U  221  1                                  10    
HELIX   14 AB5 ASP U  225  GLU U  239  1                                  15    
HELIX   15 AB6 MET U  244  ALA U  256  1                                  13    
HELIX   16 AB7 SER U  257  ARG U  269  1                                  13    
HELIX   17 AB8 GLN U  321  GLY U  331  1                                  11    
HELIX   18 AB9 GLY U  331  ASN U  345  1                                  15    
HELIX   19 AC1 ASP U  349  ASP U  358  1                                  10    
HELIX   20 AC2 VAL U  364  HIS U  377  1                                  14    
HELIX   21 AC3 GLN U  384  ASN U  389  1                                   6    
HELIX   22 AC4 LEU U  390  ARG U  395  1                                   6    
HELIX   23 AC5 ASN U  398  HIS U  412  1                                  15    
HELIX   24 AC6 ALA U  436  HIS U  450  1                                  15    
HELIX   25 AC7 ASP U  456  LYS U  466  1                                  11    
HELIX   26 AC8 ASP U  471  ALA U  485  1                                  15    
HELIX   27 AC9 GLN U  491  TYR U  502  1                                  12    
HELIX   28 AD1 VAL U  507  MET U  520  1                                  14    
HELIX   29 AD2 ALA U  526  ALA U  536  1                                  11    
HELIX   30 AD3 GLU U  542  VAL U  555  1                                  14    
HELIX   31 AD4 ARG U  559  GLU U  562  5                                   4    
HELIX   32 AD5 ALA U  563  ASP U  573  1                                  11    
HELIX   33 AD6 ASP U  575  CYS U  591  1                                  17    
HELIX   34 AD7 ASN U  595  ASP U  609  1                                  15    
HELIX   35 AD8 ASN U  611  LEU U  626  1                                  16    
HELIX   36 AD9 GLN U  632  VAL U  637  1                                   6    
HELIX   37 AE1 SER U  638  GLU U  642  5                                   5    
HELIX   38 AE2 ASN U  645  CYS U  660  1                                  16    
HELIX   39 AE3 ASN U  665  GLU U  673  1                                   9    
HELIX   40 AE4 PRO U  674  ASP U  678  5                                   5    
HELIX   41 AE5 VAL U  680  MET U  695  1                                  16    
HELIX   42 AE6 PRO U  704  ASP U  719  1                                  16    
HELIX   43 AE7 ASP U  723  ASP U  738  1                                  16    
HELIX   44 AE8 ALA U  739  HIS U  742  5                                   4    
HELIX   45 AE9 HIS U  756  THR U  767  1                                  12    
HELIX   46 AF1 TRP U  772  LEU U  781  5                                  10    
HELIX   47 AF2 LYS U  807  ALA U  812  1                                   6    
HELIX   48 AF3 MET U  885  LEU U  889  5                                   5    
HELIX   49 AF4 PRO V   19  GLN V   24  1                                   6    
HELIX   50 AF5 PRO V   29  GLY V   53  1                                  25    
HELIX   51 AF6 ALA V   60  ASP V   74  1                                  15    
HELIX   52 AF7 GLY V   88  LEU V   95  1                                   8    
HELIX   53 AF8 MET V  100  GLY V  119  1                                  20    
HELIX   54 AF9 THR V  127  ASP V  129  5                                   3    
HELIX   55 AG1 PHE V  130  GLU V  142  1                                  13    
HELIX   56 AG2 PHE V  147  LEU V  160  1                                  14    
HELIX   57 AG3 PRO V  161  TYR V  166  5                                   6    
HELIX   58 AG4 VAL V  171  ASP V  189  1                                  19    
HELIX   59 AG5 ASN V  199  PHE V  220  1                                  22    
HELIX   60 AG6 ASP V  225  ALA V  238  1                                  14    
HELIX   61 AG7 HIS V  242  TYR V  261  1                                  20    
HELIX   62 AG8 TYR V  264  LYS V  273  1                                  10    
HELIX   63 AG9 ASN V  282  GLN V  299  1                                  18    
HELIX   64 AH1 GLU V  301  LYS V  315  1                                  15    
HELIX   65 AH2 GLY V  323  ILE V  333  1                                  11    
HELIX   66 AH3 ILE V  333  LEU V  338  1                                   6    
HELIX   67 AH4 ARG V  345  ARG V  349  5                                   5    
HELIX   68 AH5 SER V  352  THR V  369  1                                  18    
HELIX   69 AH6 ASN V  371  GLY V  390  1                                  20    
HELIX   70 AH7 THR V  393  TYR V  414  1                                  22    
HELIX   71 AH8 ASP V  433  ASP V  444  1                                  12    
HELIX   72 AH9 THR V  469  LYS V  492  1                                  24    
HELIX   73 AI1 LEU W  222  GLU W  237  1                                  16    
HELIX   74 AI2 SER W  242  ILE W  250  1                                   9    
HELIX   75 AI3 TYR W  251  GLN W  257  1                                   7    
HELIX   76 AI4 SER W  260  LEU W  272  1                                  13    
HELIX   77 AI5 ASP W  280  SER W  291  1                                  12    
HELIX   78 AI6 LYS W  295  GLU W  298  5                                   4    
HELIX   79 AI7 ILE W  299  THR W  310  1                                  12    
HELIX   80 AI8 ARG W  316  MET W  326  1                                  11    
HELIX   81 AI9 GLU W  334  VAL W  340  1                                   7    
HELIX   82 AJ1 SER W  343  TYR W  370  1                                  28    
HELIX   83 AJ2 MET W  375  ASP W  383  1                                   9    
HELIX   84 AJ3 SER W  385  VAL W  398  1                                  14    
HELIX   85 AJ4 ASN W  426  ASN W  440  1                                  15    
HELIX   86 AJ5 ASN W  440  LEU W  455  1                                  16    
HELIX   87 AJ6 ILE X  347  LYS X  355  1                                   9    
HELIX   88 AJ7 SER X  357  ASP X  371  1                                  15    
HELIX   89 AJ8 VAL X  393  ALA X  418  1                                  26    
HELIX   90 AJ9 LYS Y   13  LEU Y   28  1                                  16    
HELIX   91 AK1 ASP Y   34  VAL Y   45  1                                  12    
HELIX   92 AK2 MET Y   50  SER Y   60  1                                  11    
HELIX   93 AK3 VAL Y   67  GLU Y   86  1                                  20    
HELIX   94 AK4 GLU Y   87  GLU Y   92  1                                   6    
HELIX   95 AK5 GLU Y   97  ARG Y  113  1                                  17    
HELIX   96 AK6 LYS Y  117  TYR Y  128  1                                  12    
HELIX   97 AK7 ALA Y  133  TYR Y  151  1                                  19    
HELIX   98 AK8 ASP Y  155  GLU Y  169  1                                  15    
HELIX   99 AK9 TRP Y  174  ILE Y  191  1                                  18    
HELIX  100 AL1 PHE Y  194  PHE Y  201  1                                   8    
HELIX  101 AL2 ASP Y  203  PHE Y  208  5                                   6    
HELIX  102 AL3 ASP Y  215  SER Y  227  1                                  13    
HELIX  103 AL4 GLU Y  232  ILE Y  241  1                                  10    
HELIX  104 AL5 GLY Y  243  SER Y  252  1                                  10    
HELIX  105 AL6 LEU Y  253  CYS Y  266  1                                  14    
HELIX  106 AL7 VAL Y  270  LYS Y  284  1                                  15    
HELIX  107 AL8 HIS Y  291  GLU Y  309  1                                  19    
HELIX  108 AL9 THR Y  315  ALA Y  320  1                                   6    
HELIX  109 AM1 GLU Y  328  GLY Y  341  1                                  14    
HELIX  110 AM2 LYS Y  362  ILE Y  387  1                                  26    
HELIX  111 AM3 HIS Z   12  VAL Z   29  1                                  18    
HELIX  112 AM4 ASP Z   71  ASN Z   86  1                                  16    
HELIX  113 AM5 ASN Z  104  LYS Z  113  1                                  10    
HELIX  114 AM6 GLU Z  166  LEU Z  176  1                                  11    
HELIX  115 AM7 THR Z  186  THR Z  217  1                                  32    
HELIX  116 AM8 ILE Z  226  ASN Z  235  1                                  10    
HELIX  117 AM9 GLN Z  243  GLY Z  290  1                                  48    
HELIX  118 AN1 PRO a    5  SER a   11  1                                   7    
HELIX  119 AN2 GLY a   17  LYS a   31  1                                  15    
HELIX  120 AN3 TRP a   34  ASP a   47  1                                  14    
HELIX  121 AN4 GLN a   52  HIS a   69  1                                  18    
HELIX  122 AN5 ASN a   72  THR a   88  1                                  17    
HELIX  123 AN6 ASP a   89  LYS a  103  1                                  15    
HELIX  124 AN7 ALA a  110  LEU a  121  1                                  12    
HELIX  125 AN8 VAL a  130  ASN a  143  1                                  14    
HELIX  126 AN9 SER a  150  GLN a  164  1                                  15    
HELIX  127 AO1 ASN a  168  VAL a  183  1                                  16    
HELIX  128 AO2 PRO a  189  LEU a  206  1                                  18    
HELIX  129 AO3 GLU a  215  MET a  218  5                                   4    
HELIX  130 AO4 HIS a  219  ASP a  229  1                                  11    
HELIX  131 AO5 ARG a  230  SER a  242  1                                  13    
HELIX  132 AO6 GLU a  246  GLN a  257  1                                  12    
HELIX  133 AO7 ASP a  260  ARG a  284  1                                  25    
HELIX  134 AO8 THR a  292  ALA a  300  1                                   9    
HELIX  135 AO9 ASN a  305  GLY a  318  1                                  14    
HELIX  136 AP1 GLN a  344  THR a  376  1                                  33    
HELIX  137 AP2 SER b   13  ARG b   17  5                                   5    
HELIX  138 AP3 THR b   24  ASN b   44  1                                  21    
HELIX  139 AP4 THR b   68  HIS b   76  1                                   9    
HELIX  140 AP5 PHE b   86  LYS b   98  1                                  13    
HELIX  141 AP6 ASN b  120  LYS b  135  1                                  16    
HELIX  142 AP7 GLU b  151  ASN b  161  1                                  11    
HELIX  143 AP8 LEU b  179  ILE b  184  1                                   6    
HELIX  144 AP9 ILE b  184  ALA b  190  1                                   7    
HELIX  145 AQ1 SER c   34  ALA c   47  1                                  14    
HELIX  146 AQ2 SER c   83  VAL c   87  5                                   5    
HELIX  147 AQ3 ASP c   88  THR c  102  1                                  15    
HELIX  148 AQ4 SER c  123  THR c  129  1                                   7    
HELIX  149 AQ5 THR c  129  SER c  137  1                                   9    
HELIX  150 AQ6 ASN c  164  VAL c  169  5                                   6    
HELIX  151 AQ7 THR c  178  LYS c  186  1                                   9    
HELIX  152 AQ8 ASN c  210  MET c  226  1                                  17    
HELIX  153 AQ9 LEU c  231  HIS c  237  1                                   7    
HELIX  154 AR1 VAL c  244  LYS c  264  1                                  21    
HELIX  155 AR2 MET c  265  ASN c  274  1                                  10    
HELIX  156 AR3 HIS c  287  PHE c  309  1                                  23    
HELIX  157 AR4 LEU d    5  TRP d    9  5                                   5    
HELIX  158 AR5 ASN d   15  LEU d   33  1                                  19    
HELIX  159 AR6 THR d   41  THR d   44  5                                   4    
HELIX  160 AR7 LYS d   45  ARG d   65  1                                  21    
HELIX  161 AR8 ASP d   67  ASP d   84  1                                  18    
HELIX  162 AR9 SER d   92  MET d   95  5                                   4    
HELIX  163 AS1 HIS d   96  GLN d  109  1                                  14    
HELIX  164 AS2 ALA d  113  LEU d  119  1                                   7    
HELIX  165 AS3 LEU d  122  GLN d  128  1                                   7    
HELIX  166 AS4 ILE d  133  TYR d  142  1                                  10    
HELIX  167 AS5 TYR d  148  ASN d  157  1                                  10    
HELIX  168 AS6 THR d  164  GLU d  183  1                                  20    
HELIX  169 AS7 PHE d  191  PHE d  199  1                                   9    
HELIX  170 AS8 LYS d  204  GLY d  214  1                                  11    
HELIX  171 AS9 THR d  236  MET d  255  1                                  20    
HELIX  172 AT1 LYS e    5  ASP e    9  5                                   5    
HELIX  173 AT2 LEU e   60  SER e   70  1                                  11    
HELIX  174 AT3 PRO A   74  ALA A   82  1                                   9    
HELIX  175 AT4 ALA A   82  SER A   89  1                                   8    
HELIX  176 AT5 THR A  160  VAL A  166  1                                   7    
HELIX  177 AT6 THR A  173  VAL A  177  5                                   5    
HELIX  178 AT7 LYS A  181  GLU A  189  1                                   9    
HELIX  179 AT8 VAL A  191  HIS A  197  1                                   7    
HELIX  180 AT9 GLU A  199  LEU A  204  1                                   6    
HELIX  181 AU1 LYS A  222  ARG A  232  1                                  11    
HELIX  182 AU2 ILE A  241  LEU A  245  5                                   5    
HELIX  183 AU3 GLY A  251  THR A  266  1                                  16    
HELIX  184 AU4 GLU A  276  GLY A  281  1                                   6    
HELIX  185 AU5 GLY A  291  GLY A  308  1                                  18    
HELIX  186 AU6 THR A  326  ARG A  333  1                                   8    
HELIX  187 AU7 GLY A  350  PHE A  355  1                                   6    
HELIX  188 AU8 ARG A  369  ARG A  375  1                                   7    
HELIX  189 AU9 GLY A  382  ARG A  400  1                                  19    
HELIX  190 AV1 THR A  405  SER A  424  1                                  20    
HELIX  191 AV2 PRO A  427  TYR A  432  1                                   6    
HELIX  192 AV3 GLU B   94  GLY B  104  1                                  11    
HELIX  193 AV4 THR B  167  VAL B  173  1                                   7    
HELIX  194 AV5 LEU B  190  LEU B  203  1                                  14    
HELIX  195 AV6 PRO B  208  GLY B  215  1                                   8    
HELIX  196 AV7 LEU B  234  GLN B  242  1                                   9    
HELIX  197 AV8 SER B  253  LYS B  258  1                                   6    
HELIX  198 AV9 PRO B  264  HIS B  277  1                                  14    
HELIX  199 AW1 GLY B  301  ASP B  317  1                                  17    
HELIX  200 AW2 ASP B  338  ILE B  342  5                                   5    
HELIX  201 AW3 ASP B  357  SER B  370  1                                  14    
HELIX  202 AW4 THR B  379  LYS B  387  1                                   9    
HELIX  203 AW5 SER B  391  GLU B  409  1                                  19    
HELIX  204 AW6 THR B  415  GLU B  432  1                                  18    
HELIX  205 AW7 GLY C   14  LEU C   66  1                                  53    
HELIX  206 AW8 VAL C  131  VAL C  143  1                                  13    
HELIX  207 AW9 LEU C  154  LYS C  170  1                                  17    
HELIX  208 AX1 HIS C  171  GLU C  173  5                                   3    
HELIX  209 AX2 LEU C  174  GLY C  179  1                                   6    
HELIX  210 AX3 GLY C  195  THR C  207  1                                  13    
HELIX  211 AX4 MET C  230  HIS C  241  1                                  12    
HELIX  212 AX5 GLY C  262  ASP C  281  1                                  20    
HELIX  213 AX6 ILE C  298  ARG C  307  1                                  10    
HELIX  214 AX7 ASN C  321  SER C  333  1                                  13    
HELIX  215 AX8 ASN C  343  LEU C  350  1                                   8    
HELIX  216 AX9 GLY C  356  ARG C  374  1                                  19    
HELIX  217 AY1 THR C  379  LYS C  393  1                                  15    
HELIX  218 AY2 LEU D   40  LEU D   47  1                                   8    
HELIX  219 AY3 GLN D   48  ILE D   82  1                                  35    
HELIX  220 AY4 MET D  163  ILE D  167  5                                   5    
HELIX  221 AY5 MET D  170  HIS D  187  1                                  18    
HELIX  222 AY6 GLU D  189  GLY D  195  1                                   7    
HELIX  223 AY7 LYS D  212  VAL D  219  1                                   8    
HELIX  224 AY8 GLY D  241  ALA D  258  1                                  18    
HELIX  225 AY9 GLU D  266  THR D  272  5                                   7    
HELIX  226 AZ1 THR D  279  ASP D  297  1                                  19    
HELIX  227 AZ2 GLY D  298  ASP D  300  5                                   3    
HELIX  228 AZ3 ASP D  337  SER D  350  1                                  14    
HELIX  229 AZ4 ARG D  366  ILE D  370  5                                   5    
HELIX  230 AZ5 ASP D  374  LEU D  385  1                                  12    
HELIX  231 AZ6 ALA D  386  GLU D  389  5                                   4    
HELIX  232 AZ7 LEU D  395  VAL D  406  1                                  12    
HELIX  233 AZ8 LYS E   38  LYS E   48  1                                  11    
HELIX  234 AZ9 ASP E   88  LEU E   92  5                                   5    
HELIX  235 BA1 ASP E  116  ASN E  121  1                                   6    
HELIX  236 BA2 ASN E  129  GLY E  136  5                                   8    
HELIX  237 BA3 LEU E  138  ASN E  155  1                                  18    
HELIX  238 BA4 PRO E  156  GLY E  163  1                                   8    
HELIX  239 BA5 GLY E  179  ASP E  192  1                                  14    
HELIX  240 BA6 SER E  201  ASP E  205  5                                   5    
HELIX  241 BA7 SER E  211  HIS E  225  1                                  15    
HELIX  242 BA8 SER E  248  ASP E  265  1                                  18    
HELIX  243 BA9 LEU E  285  ARG E  291  1                                   7    
HELIX  244 BB1 ASN E  305  GLY E  318  1                                  14    
HELIX  245 BB2 ASP E  327  SER E  335  1                                   9    
HELIX  246 BB3 ASN E  339  ILE E  355  1                                  17    
HELIX  247 BB4 ARG E  356  ASP E  358  5                                   3    
HELIX  248 BB5 VAL E  363  LYS E  379  1                                  17    
HELIX  249 BB6 GLU F   65  ASN F   83  1                                  19    
HELIX  250 BB7 ASN F  154  TYR F  158  5                                   5    
HELIX  251 BB8 ASP F  169  ALA F  174  1                                   6    
HELIX  252 BB9 GLN F  184  ILE F  188  5                                   5    
HELIX  253 BC1 LEU F  191  ASN F  207  1                                  17    
HELIX  254 BC2 HIS F  208  GLY F  216  1                                   9    
HELIX  255 BC3 GLY F  232  CYS F  240  1                                   9    
HELIX  256 BC4 ALA F  241  GLN F  243  5                                   3    
HELIX  257 BC5 ALA F  252  VAL F  257  1                                   6    
HELIX  258 BC6 GLY F  262  ALA F  279  1                                  18    
HELIX  259 BC7 GLU F  287  THR F  293  1                                   7    
HELIX  260 BC8 GLY F  302  ASP F  318  1                                  17    
HELIX  261 BC9 GLN F  321  GLN F  325  5                                   5    
HELIX  262 BD1 ASP F  339  LEU F  343  5                                   5    
HELIX  263 BD2 ASN F  358  ARG F  371  1                                  14    
HELIX  264 BD3 TYR F  381  THR F  388  1                                   8    
HELIX  265 BD4 ASN F  392  ARG F  410  1                                  19    
HELIX  266 BD5 THR F  416  GLN F  428  1                                  13    
HELIX  267 BD6 TYR G   23  PHE G   29  1                                   7    
HELIX  268 BD7 MET G   83  GLY G  106  1                                  24    
HELIX  269 BD8 PRO G  110  ASN G  128  1                                  19    
HELIX  270 BD9 LYS G  171  LYS G  184  1                                  14    
HELIX  271 BE1 THR G  190  SER G  207  1                                  18    
HELIX  272 BE2 THR G  231  LEU G  242  1                                  12    
HELIX  273 BE3 LEU H   19  GLY H   31  1                                  13    
HELIX  274 BE4 MET H   79  TYR H  101  1                                  23    
HELIX  275 BE5 PRO H  106  THR H  122  1                                  17    
HELIX  276 BE6 VAL H  168  ARG H  177  1                                  10    
HELIX  277 BE7 GLU H  183  LYS H  196  1                                  14    
HELIX  278 BE8 THR H  222  LEU H  230  1                                   9    
HELIX  279 BE9 LEU I   18  GLY I   29  1                                  12    
HELIX  280 BF1 ILE I   79  GLN I  102  1                                  24    
HELIX  281 BF2 PRO I  106  PHE I  124  1                                  19    
HELIX  282 BF3 GLY I  165  ASN I  167  5                                   3    
HELIX  283 BF4 SER I  168  ASP I  178  1                                  11    
HELIX  284 BF5 THR I  185  MET I  201  1                                  17    
HELIX  285 BF6 GLN I  230  GLU I  248  1                                  19    
HELIX  286 BF7 ARG I  249  LYS I  251  5                                   3    
HELIX  287 BF8 LEU J   16  ALA J   22  1                                   7    
HELIX  288 BF9 GLN J   23  LYS J   28  1                                   6    
HELIX  289 BG1 LEU J   76  THR J   97  1                                  22    
HELIX  290 BG2 THR J  103  SER J  121  1                                  19    
HELIX  291 BG3 PHE J  138  GLY J  140  5                                   3    
HELIX  292 BG4 GLY J  164  LEU J  172  1                                   9    
HELIX  293 BG5 THR J  183  LEU J  195  1                                  13    
HELIX  294 BG6 GLU J  224  ASN J  239  1                                  16    
HELIX  295 BG7 LEU K   21  LEU K   33  1                                  13    
HELIX  296 BG8 GLU K   60  ILE K   64  5                                   5    
HELIX  297 BG9 LEU K   81  ASN K  104  1                                  24    
HELIX  298 BH1 THR K  108  ASN K  118  1                                  11    
HELIX  299 BH2 ALA K  173  GLN K  182  1                                  10    
HELIX  300 BH3 THR K  190  MET K  206  1                                  17    
HELIX  301 BH4 GLU K  232  LYS K  239  1                                   8    
HELIX  302 BH5 ILE L   19  GLN L   31  1                                  13    
HELIX  303 BH6 THR L   78  PHE L   99  1                                  22    
HELIX  304 BH7 PRO L  104  ARG L  107  5                                   4    
HELIX  305 BH8 LEU L  108  GLN L  117  1                                  10    
HELIX  306 BH9 ILE L  118  GLN L  121  5                                   4    
HELIX  307 BI1 SER L  165  GLU L  173  1                                   9    
HELIX  308 BI2 ASN L  183  THR L  198  1                                  16    
HELIX  309 BI3 VAL M   20  LYS M   28  1                                   9    
HELIX  310 BI4 ALA M   29  SER M   33  5                                   5    
HELIX  311 BI5 LEU M   81  GLY M  103  1                                  23    
HELIX  312 BI6 PRO M  107  TYR M  122  1                                  16    
HELIX  313 BI7 THR M  174  LEU M  179  5                                   6    
HELIX  314 BI8 THR M  185  VAL M  200  1                                  16    
HELIX  315 BI9 GLU M  233  LYS M  240  1                                   8    
HELIX  316 BJ1 GLU M  241  LEU M  243  5                                   3    
HELIX  317 BJ2 SER N   48  ASN N   71  1                                  24    
HELIX  318 BJ3 LEU N   75  TYR N   90  1                                  16    
HELIX  319 BJ4 GLY N  129  TYR N  134  5                                   6    
HELIX  320 BJ5 ILE N  135  TYR N  143  1                                   9    
HELIX  321 BJ6 THR N  148  ASP N  167  1                                  20    
HELIX  322 BJ7 THR O   48  GLY O   71  1                                  24    
HELIX  323 BJ8 ARG O   75  TYR O   90  1                                  16    
HELIX  324 BJ9 GLY O  130  LYS O  141  1                                  12    
HELIX  325 BK1 GLU O  147  PHE O  164  1                                  18    
HELIX  326 BK2 ILE P    3  ASN P    7  5                                   5    
HELIX  327 BK3 LEU P   56  GLU P   78  1                                  23    
HELIX  328 BK4 LYS P   83  GLU P   97  1                                  15    
HELIX  329 BK5 ALA P  143  GLU P  151  1                                   9    
HELIX  330 BK6 ASP P  159  ASP P  176  1                                  18    
HELIX  331 BK7 GLY Q   51  GLY Q   72  1                                  22    
HELIX  332 BK8 SER Q   76  ARG Q   93  1                                  18    
HELIX  333 BK9 HIS Q  132  TYR Q  134  5                                   3    
HELIX  334 BL1 GLY Q  135  LEU Q  140  1                                   6    
HELIX  335 BL2 SER Q  141  TYR Q  146  1                                   6    
HELIX  336 BL3 SER Q  152  GLN Q  168  1                                  17    
HELIX  337 BL4 ALA R   49  LYS R   71  1                                  23    
HELIX  338 BL5 SER R   75  GLN R   89  1                                  15    
HELIX  339 BL6 SER R  132  ASP R  140  1                                   9    
HELIX  340 BL7 GLU R  148  ASP R  167  1                                  20    
HELIX  341 BL8 VAL R  192  SER R  200  1                                   9    
HELIX  342 BL9 PHE S   57  ASN S   80  1                                  24    
HELIX  343 BM1 THR S   84  ARG S   99  1                                  16    
HELIX  344 BM2 GLY S  139  MET S  144  5                                   6    
HELIX  345 BM3 LEU S  145  VAL S  153  1                                   9    
HELIX  346 BM4 SER S  167  ASP S  186  1                                  20    
HELIX  347 BM5 ASP T   56  GLY T   78  1                                  23    
HELIX  348 BM6 SER T   84  SER T  101  1                                  18    
HELIX  349 BM7 TYR T  141  ALA T  146  1                                   6    
HELIX  350 BM8 ALA T  146  GLN T  157  1                                  12    
HELIX  351 BM9 SER T  161  ASP T  180  1                                  20    
HELIX  352 BN1 ALA g    7  HIS g   12  5                                   6    
HELIX  353 BN2 TYR g   23  LYS g   30  1                                   8    
HELIX  354 BN3 ALA g   31  GLY g   35  5                                   5    
HELIX  355 BN4 MET g   83  TYR g  105  1                                  23    
HELIX  356 BN5 PRO g  110  ASN g  128  1                                  19    
HELIX  357 BN6 LYS g  171  LYS g  184  1                                  14    
HELIX  358 BN7 THR g  190  SER g  207  1                                  18    
HELIX  359 BN8 THR g  231  ALA g  243  1                                  13    
HELIX  360 BN9 LEU h   19  GLY h   31  1                                  13    
HELIX  361 BO1 MET h   79  GLN h  102  1                                  24    
HELIX  362 BO2 PRO h  106  SER h  124  1                                  19    
HELIX  363 BO3 ASN h  166  ARG h  177  1                                  12    
HELIX  364 BO4 GLU h  183  PHE h  199  1                                  17    
HELIX  365 BO5 THR h  222  LEU h  230  1                                   9    
HELIX  366 BO6 LEU i   18  HIS i   30  1                                  13    
HELIX  367 BO7 ILE i   79  GLN i  102  1                                  24    
HELIX  368 BO8 PRO i  106  PHE i  124  1                                  19    
HELIX  369 BO9 GLY i  165  ASN i  167  5                                   3    
HELIX  370 BP1 SER i  168  ASP i  178  1                                  11    
HELIX  371 BP2 THR i  185  MET i  201  1                                  17    
HELIX  372 BP3 GLN i  230  GLU i  248  1                                  19    
HELIX  373 BP4 PHE j   17  ALA j   22  1                                   6    
HELIX  374 BP5 GLN j   23  LYS j   28  1                                   6    
HELIX  375 BP6 LEU j   76  VAL j   98  1                                  23    
HELIX  376 BP7 THR j  103  SER j  121  1                                  19    
HELIX  377 BP8 GLY j  164  GLU j  173  1                                  10    
HELIX  378 BP9 ASP j  184  VAL j  198  1                                  15    
HELIX  379 BQ1 PRO j  222  ASN j  239  1                                  18    
HELIX  380 BQ2 LEU k   21  LEU k   33  1                                  13    
HELIX  381 BQ3 ASP k   84  ASN k  104  1                                  21    
HELIX  382 BQ4 THR k  108  ASN k  118  1                                  11    
HELIX  383 BQ5 ALA k  173  TYR k  185  1                                  13    
HELIX  384 BQ6 THR k  190  MET k  206  1                                  17    
HELIX  385 BQ7 GLU k  233  LYS k  239  1                                   7    
HELIX  386 BQ8 ASP k  240  ILE k  241  5                                   2    
HELIX  387 BQ9 ASN l    4  ASN l    8  5                                   5    
HELIX  388 BR1 ILE l   19  LYS l   30  1                                  12    
HELIX  389 BR2 THR l   78  PHE l   99  1                                  22    
HELIX  390 BR3 PRO l  104  THR l  116  1                                  13    
HELIX  391 BR4 GLN l  117  GLN l  121  5                                   5    
HELIX  392 BR5 ARG l  164  GLU l  173  1                                  10    
HELIX  393 BR6 SER l  177  GLU l  181  5                                   5    
HELIX  394 BR7 ASN l  183  ARG l  196  1                                  14    
HELIX  395 BR8 VAL m   20  GLU m   31  1                                  12    
HELIX  396 BR9 LEU m   80  GLY m  103  1                                  24    
HELIX  397 BS1 PRO m  107  TYR m  122  1                                  16    
HELIX  398 BS2 GLU m  175  LEU m  179  5                                   5    
HELIX  399 BS3 THR m  185  VAL m  200  1                                  16    
HELIX  400 BS4 LEU m  219  ASN m  221  5                                   3    
HELIX  401 BS5 GLU m  233  LYS m  240  1                                   8    
HELIX  402 BS6 SER n   48  LEU n   70  1                                  23    
HELIX  403 BS7 LEU n   75  TYR n   90  1                                  16    
HELIX  404 BS8 GLY n  129  TYR n  134  5                                   6    
HELIX  405 BS9 ILE n  135  THR n  142  1                                   8    
HELIX  406 BT1 THR n  148  ASP n  167  1                                  20    
HELIX  407 BT2 THR o   48  GLY o   71  1                                  24    
HELIX  408 BT3 ARG o   75  TYR o   90  1                                  16    
HELIX  409 BT4 GLY o  130  PHE o  142  1                                  13    
HELIX  410 BT5 GLU o  147  ASP o  166  1                                  20    
HELIX  411 BT6 LEU p   56  GLU p   78  1                                  23    
HELIX  412 BT7 LYS p   83  LYS p   98  1                                  16    
HELIX  413 BT8 CYS p  142  TRP p  154  1                                  13    
HELIX  414 BT9 ASP p  159  ASP p  176  1                                  18    
HELIX  415 BU1 GLU q   49  GLY q   51  5                                   3    
HELIX  416 BU2 ASP q   52  GLY q   72  1                                  21    
HELIX  417 BU3 SER q   76  ARG q   93  1                                  18    
HELIX  418 BU4 GLY q  135  LEU q  138  5                                   4    
HELIX  419 BU5 THR q  139  TYR q  146  1                                   8    
HELIX  420 BU6 SER q  152  PHE q  171  1                                  20    
HELIX  421 BU7 GLY r   48  LYS r   71  1                                  24    
HELIX  422 BU8 VAL r   76  GLN r   89  1                                  14    
HELIX  423 BU9 GLY r  131  TYR r  143  1                                  13    
HELIX  424 BV1 GLU r  148  ASP r  167  1                                  20    
HELIX  425 BV2 VAL r  192  SER r  200  1                                   9    
HELIX  426 BV3 PHE s   57  ASN s   80  1                                  24    
HELIX  427 BV4 THR s   84  ARG s   99  1                                  16    
HELIX  428 BV5 ALA s  141  VAL s  153  1                                  13    
HELIX  429 BV6 SER s  167  GLU s  184  1                                  18    
HELIX  430 BV7 TYR t   57  LEU t   76  1                                  20    
HELIX  431 BV8 SER t   84  SER t  101  1                                  18    
HELIX  432 BV9 TYR t  141  ALA t  146  1                                   6    
HELIX  433 BW1 ALA t  146  GLN t  157  1                                  12    
HELIX  434 BW2 SER t  161  ARG t  179  1                                  19    
HELIX  435 BW3 TRP t  209  HIS t  213  5                                   5    
HELIX  436 BW4 VAL f   11  SER f   16  5                                   6    
HELIX  437 BW5 ALA f   19  ARG f   33  1                                  15    
HELIX  438 BW6 ARG f   34  ALA f   36  5                                   3    
HELIX  439 BW7 GLU f   44  ASP f   49  1                                   6    
HELIX  440 BW8 LYS f   50  GLN f   53  5                                   4    
HELIX  441 BW9 TYR f   71  THR f   87  1                                  17    
HELIX  442 BX1 PRO f   93  PHE f   98  1                                   6    
HELIX  443 BX2 LYS f  119  ILE f  126  1                                   8    
HELIX  444 BX3 ILE f  126  VAL f  145  1                                  20    
HELIX  445 BX4 GLY f  164  ARG f  181  1                                  18    
HELIX  446 BX5 LEU f  184  VAL f  192  1                                   9    
HELIX  447 BX6 LEU f  208  LEU f  217  1                                  10    
HELIX  448 BX7 ILE f  221  TYR f  239  1                                  19    
HELIX  449 BX8 GLU f  242  PHE f  259  1                                  18    
HELIX  450 BX9 PHE f  262  ASN f  273  1                                  12    
HELIX  451 BY1 MET f  275  VAL f  288  1                                  14    
HELIX  452 BY2 LEU f  298  GLU f  309  1                                  12    
HELIX  453 BY3 GLU f  312  VAL f  324  1                                  13    
HELIX  454 BY4 SER f  328  ALA f  334  1                                   7    
HELIX  455 BY5 PRO f  342  THR f  351  1                                  10    
HELIX  456 BY6 ASN f  355  GLY f  360  1                                   6    
HELIX  457 BY7 ARG f  369  PHE f  380  1                                  12    
HELIX  458 BY8 LYS f  403  ILE f  417  1                                  15    
HELIX  459 BY9 ASP f  421  LEU f  433  1                                  13    
HELIX  460 BZ1 GLU f  437  ASN f  452  1                                  16    
HELIX  461 BZ2 GLU f  458  ALA f  464  1                                   7    
HELIX  462 BZ3 HIS f  472  SER f  474  5                                   3    
HELIX  463 BZ4 ASN f  475  TYR f  489  1                                  15    
HELIX  464 BZ5 GLU f  495  GLY f  506  1                                  12    
HELIX  465 BZ6 MET f  512  VAL f  527  1                                  16    
HELIX  466 BZ7 THR f  535  GLU f  544  1                                  10    
HELIX  467 BZ8 THR f  553  LEU f  567  1                                  15    
HELIX  468 BZ9 ILE f  573  VAL f  583  1                                  11    
HELIX  469 CA1 GLU f  585  ALA f  599  1                                  15    
HELIX  470 CA2 VAL f  606  CYS f  616  1                                  11    
HELIX  471 CA3 SER f  622  ASP f  630  1                                   9    
HELIX  472 CA4 ASP f  630  LYS f  635  1                                   6    
HELIX  473 CA5 VAL f  652  GLY f  663  1                                  12    
HELIX  474 CA6 ALA f  668  ARG f  680  1                                  13    
HELIX  475 CA7 ALA f  689  ILE f  697  1                                   9    
HELIX  476 CA8 ALA f  717  ALA f  728  1                                  12    
HELIX  477 CA9 ARG f  740  LYS f  754  1                                  15    
HELIX  478 CB1 GLY f  774  THR f  777  5                                   4    
HELIX  479 CB2 LEU f  778  ARG f  785  1                                   8    
HELIX  480 CB3 GLN f  790  GLY f  795  1                                   6    
SHEET    1 AA1 2 VAL U 744  ILE U 746  0                                        
SHEET    2 AA1 2 TYR U 783  PRO U 785 -1  O  THR U 784   N  THR U 745           
SHEET    1 AA2 3 ALA U 882  ARG U 883  0                                        
SHEET    2 AA2 3 CYS U 787  ILE U 789 -1  N  VAL U 788   O  ALA U 882           
SHEET    3 AA2 3 GLY U 910  ILE U 911  1  O  GLY U 910   N  CYS U 787           
SHEET    1 AA3 2 TYR U 900  GLN U 901  0                                        
SHEET    2 AA3 2 LYS U 915  ASP U 916 -1  O  LYS U 915   N  GLN U 901           
SHEET    1 AA4 3 ARG V 416  SER V 418  0                                        
SHEET    2 AA4 3 TYR V 457  GLN V 459 -1  O  VAL V 458   N  ILE V 417           
SHEET    3 AA4 3 SER V 450  ASN V 452 -1  N  SER V 450   O  GLN V 459           
SHEET    1 AA5 3 ARG W 372  THR W 374  0                                        
SHEET    2 AA5 3 ILE W 412  PHE W 415 -1  O  ILE W 413   N  ILE W 373           
SHEET    3 AA5 3 ALA W 404  LYS W 405 -1  N  LYS W 405   O  ASN W 414           
SHEET    1 AA6 3 VAL X 345  GLN X 346  0                                        
SHEET    2 AA6 3 VAL X 384  ILE X 386 -1  O  LEU X 385   N  VAL X 345           
SHEET    3 AA6 3 ILE X 377  ASP X 379 -1  N  ASP X 379   O  VAL X 384           
SHEET    1 AA7 3 SER Y 313  LEU Y 314  0                                        
SHEET    2 AA7 3 ILE Y 353  GLU Y 355 -1  O  VAL Y 354   N  LEU Y 314           
SHEET    3 AA7 3 LYS Y 346  ASP Y 348 -1  N  ASP Y 348   O  ILE Y 353           
SHEET    1 AA8 8 GLU Z 156  HIS Z 157  0                                        
SHEET    2 AA8 8 TYR Z 138  ILE Z 139 -1  N  ILE Z 139   O  GLU Z 156           
SHEET    3 AA8 8 VAL Z 120  ILE Z 123 -1  N  LEU Z 121   O  TYR Z 138           
SHEET    4 AA8 8 ARG Z  90  HIS Z  96  1  N  HIS Z  96   O  VAL Z 122           
SHEET    5 AA8 8 VAL Z  36  TRP Z  43 -1  N  LEU Z  39   O  GLY Z  93           
SHEET    6 AA8 8 LEU Z  48  ALA Z  55 -1  O  ASP Z  49   N  SER Z  42           
SHEET    7 AA8 8 LYS Z   8  VAL Z  11  1  N  LYS Z   8   O  LEU Z  48           
SHEET    8 AA8 8 THR Z 159  ILE Z 162  1  O  GLU Z 161   N  VAL Z  11           
SHEET    1 AA9 3 GLN a 290  LEU a 291  0                                        
SHEET    2 AA9 3 ARG a 330  HIS a 332 -1  O  VAL a 331   N  LEU a 291           
SHEET    3 AA9 3 SER a 323  ASP a 325 -1  N  SER a 323   O  HIS a 332           
SHEET    1 AB1 5 LEU b  51  THR b  53  0                                        
SHEET    2 AB1 5 GLU b   4  VAL b  10  1  N  VAL b  10   O  ILE b  52           
SHEET    3 AB1 5 LYS b 106  VAL b 113  1  O  LYS b 106   N  SER b   5           
SHEET    4 AB1 5 ASN b 137  ASN b 142  1  O  ASP b 139   N  ILE b 109           
SHEET    5 AB1 5 VAL b 171  THR b 172  1  O  VAL b 171   N  ASN b 142           
SHEET    1 AB2 5 VAL c 108  TYR c 112  0                                        
SHEET    2 AB2 5 GLY c  55  GLU c  60 -1  N  GLY c  55   O  TYR c 112           
SHEET    3 AB2 5 VAL c  67  ALA c  74 -1  O  PHE c  73   N  LEU c  56           
SHEET    4 AB2 5 GLN c  30  ILE c  33  1  N  TYR c  32   O  VAL c  67           
SHEET    5 AB2 5 THR c 204  TYR c 207  1  O  THR c 204   N  VAL c  31           
SHEET    1 AB3 2 ARG c 161  LEU c 162  0                                        
SHEET    2 AB3 2 TYR c 200  TYR c 201 -1  O  TYR c 201   N  ARG c 161           
SHEET    1 AB4 2 ILE d 189  LEU d 190  0                                        
SHEET    2 AB4 2 ASN d 221  TYR d 222 -1  O  TYR d 222   N  ILE d 189           
SHEET    1 AB5 4 LYS A 120  VAL A 122  0                                        
SHEET    2 AB5 4 ILE A 112  ASN A 114 -1  N  ILE A 113   O  PHE A 121           
SHEET    3 AB5 4 LYS A 100  ALA A 104 -1  N  ILE A 101   O  ASN A 114           
SHEET    4 AB5 4 ARG A 139  VAL A 140 -1  O  VAL A 140   N  LYS A 100           
SHEET    1 AB6 3 LEU A 214  PHE A 215  0                                        
SHEET    2 AB6 3 LEU A 318  THR A 321  1  O  THR A 321   N  LEU A 214           
SHEET    3 AB6 3 PHE A 273  PHE A 274  1  N  PHE A 274   O  ALA A 320           
SHEET    1 AB7 6 MET B 107  SER B 108  0                                        
SHEET    2 AB7 6 LYS C  94  ASP C  98 -1  O  VAL C  96   N  MET B 107           
SHEET    3 AB7 6 LYS C  84  LYS C  88 -1  N  VAL C  85   O  VAL C  97           
SHEET    4 AB7 6 GLY C  74  ALA C  79 -1  N  ARG C  78   O  LEU C  86           
SHEET    5 AB7 6 CYS C 112  LEU C 116 -1  O  VAL C 114   N  GLY C  74           
SHEET    6 AB7 6 LEU C 123  LEU C 127 -1  O  HIS C 124   N  ALA C 115           
SHEET    1 AB8 2 LEU B 151  LEU B 152  0                                        
SHEET    2 AB8 2 VAL B 159  GLY B 161 -1  O  ILE B 160   N  LEU B 151           
SHEET    1 AB9 5 PHE B 247  VAL B 251  0                                        
SHEET    2 AB9 5 ILE B 281  ASP B 285  1  O  PHE B 283   N  VAL B 250           
SHEET    3 AB9 5 LYS B 326  ALA B 330  1  O  ILE B 328   N  VAL B 282           
SHEET    4 AB9 5 VAL B 222  LEU B 224  1  N  LEU B 224   O  MET B 329           
SHEET    5 AB9 5 LYS B 350  ILE B 351  1  O  ILE B 351   N  ILE B 223           
SHEET    1 AC1 2 THR B 373  LEU B 374  0                                        
SHEET    2 AC1 2 LYS B 413  VAL B 414  1  O  VAL B 414   N  THR B 373           
SHEET    1 AC2 5 THR C 210  PHE C 211  0                                        
SHEET    2 AC2 5 SER C 244  ILE C 245  1  O  ILE C 245   N  THR C 210           
SHEET    3 AC2 5 ILE C 289  THR C 295  1  O  LYS C 290   N  SER C 244           
SHEET    4 AC2 5 GLY C 185  TYR C 189  1  N  VAL C 186   O  MET C 293           
SHEET    5 AC2 5 ILE C 315  GLU C 316  1  O  ILE C 315   N  TYR C 189           
SHEET    1 AC3 5 ASN D 110  ARG D 114  0                                        
SHEET    2 AC3 5 THR D 100  GLY D 104 -1  N  ALA D 101   O  VAL D 113           
SHEET    3 AC3 5 VAL D  88  ASP D  97 -1  N  GLN D  91   O  GLY D 104           
SHEET    4 AC3 5 SER D 129  LEU D 132 -1  O  LEU D 132   N  VAL D  88           
SHEET    5 AC3 5 LEU D 139  VAL D 142 -1  O  ASP D 141   N  ALA D 131           
SHEET    1 AC4 3 ARG D 229  VAL D 230  0                                        
SHEET    2 AC4 3 ILE D 262  ILE D 264  1  N  PHE D 263   O  VAL D 230           
SHEET    3 AC4 3 VAL D 307  ILE D 308  1  O  ILE D 308   N  ILE D 264           
SHEET    1 AC5 5 ARG E  78  VAL E  81  0                                        
SHEET    2 AC5 5 LYS E  68  LYS E  72 -1  N  VAL E  71   O  TYR E  79           
SHEET    3 AC5 5 GLN E  55  THR E  65 -1  N  LEU E  61   O  ILE E  70           
SHEET    4 AC5 5 THR E  96  LEU E 100 -1  O  VAL E  98   N  GLY E  58           
SHEET    5 AC5 5 ILE E 107  TYR E 110 -1  O  ARG E 109   N  ALA E  99           
SHEET    1 AC6 6 ARG E  78  VAL E  81  0                                        
SHEET    2 AC6 6 LYS E  68  LYS E  72 -1  N  VAL E  71   O  TYR E  79           
SHEET    3 AC6 6 GLN E  55  THR E  65 -1  N  LEU E  61   O  ILE E  70           
SHEET    4 AC6 6 THR F 131  PRO F 135 -1  O  PHE F 133   N  GLN E  55           
SHEET    5 AC6 6 CYS F 121  LYS F 125 -1  N  ALA F 122   O  LEU F 134           
SHEET    6 AC6 6 VAL F  93  GLU F  95 -1  N  ILE F  94   O  VAL F 123           
SHEET    1 AC7 4 GLY E 169  LEU E 171  0                                        
SHEET    2 AC7 4 VAL E 273  ALA E 278  1  O  MET E 275   N  CYS E 170           
SHEET    3 AC7 4 CYS E 228  ASP E 233  1  N  ILE E 230   O  LYS E 274           
SHEET    4 AC7 4 LEU E 196  VAL E 198  1  N  LEU E 196   O  ILE E 229           
SHEET    1 AC8 5 THR F 247  LYS F 250  0                                        
SHEET    2 AC8 5 SER F 281  PHE F 284  1  O  ILE F 282   N  THR F 247           
SHEET    3 AC8 5 VAL F 328  ALA F 331  1  O  ILE F 329   N  ILE F 283           
SHEET    4 AC8 5 VAL F 223  MET F 225  1  N  MET F 225   O  ALA F 330           
SHEET    5 AC8 5 ARG F 350  ILE F 352  1  O  ARG F 350   N  LEU F 224           
SHEET    1 AC9 5 ALA G 165  THR G 166  0                                        
SHEET    2 AC9 5 VAL G  40  ARG G  43 -1  N  ALA G  41   O  THR G 166           
SHEET    3 AC9 5 CYS G  47  VAL G  51 -1  O  VAL G  49   N  VAL G  42           
SHEET    4 AC9 5 VAL G 217  THR G 221 -1  O  GLY G 218   N  ILE G  50           
SHEET    5 AC9 5 ASN G 224  ILE G 229 -1  O  ARG G 228   N  VAL G 219           
SHEET    1 AD1 5 PHE G  70  THR G  73  0                                        
SHEET    2 AD1 5 ILE G  76  GLY G  82 -1  O  CYS G  78   N  PHE G  70           
SHEET    3 AD1 5 CYS G 136  ASP G 144 -1  O  ILE G 139   N  VAL G  79           
SHEET    4 AD1 5 GLY G 148  CYS G 154 -1  O  CYS G 154   N  MET G 138           
SHEET    5 AD1 5 TYR G 160  CYS G 161 -1  O  CYS G 161   N  LYS G 153           
SHEET    1 AD2 5 ALA H 160  MET H 163  0                                        
SHEET    2 AD2 5 SER H  35  ALA H  40 -1  N  GLY H  37   O  THR H 161           
SHEET    3 AD2 5 GLY H  43  GLU H  49 -1  O  ALA H  47   N  VAL H  36           
SHEET    4 AD2 5 ILE H 208  CYS H 213 -1  O  GLY H 211   N  LEU H  46           
SHEET    5 AD2 5 PHE H 218  ARG H 220 -1  O  ARG H 219   N  ILE H 212           
SHEET    1 AD3 5 GLU H  66  PRO H  67  0                                        
SHEET    2 AD3 5 GLY H  73  GLY H  78 -1  O  LEU H  74   N  GLU H  66           
SHEET    3 AD3 5 VAL H 132  ASN H 140 -1  O  LEU H 135   N  VAL H  75           
SHEET    4 AD3 5 ARG H 143  SER H 149 -1  O  PHE H 147   N  ILE H 136           
SHEET    5 AD3 5 TYR H 155  ALA H 157 -1  O  PHE H 156   N  GLN H 148           
SHEET    1 AD4 4 CYS I  34  GLY I  36  0                                        
SHEET    2 AD4 4 LEU I  44  GLU I  48 -1  O  ALA I  46   N  LEU I  35           
SHEET    3 AD4 4 VAL I 211  THR I 217 -1  O  ALA I 214   N  LEU I  45           
SHEET    4 AD4 4 VAL I 224  VAL I 227 -1  O  ARG I 226   N  THR I 215           
SHEET    1 AD5 4 ILE I  65  LYS I  67  0                                        
SHEET    2 AD5 4 MET I  72  SER I  75 -1  O  CYS I  74   N  TYR I  66           
SHEET    3 AD5 4 LEU I 135  ASP I 140 -1  O  ILE I 137   N  ALA I  73           
SHEET    4 AD5 4 GLY I 144  GLN I 149 -1  O  TYR I 148   N  TYR I 136           
SHEET    1 AD6 4 ALA J  32  ARG J  36  0                                        
SHEET    2 AD6 4 VAL J  41  VAL J  45 -1  O  GLY J  44   N  VAL J  33           
SHEET    3 AD6 4 GLU J 207  MET J 211 -1  O  ALA J 209   N  LEU J  43           
SHEET    4 AD6 4 LYS J 218  ILE J 219 -1  O  LYS J 218   N  VAL J 210           
SHEET    1 AD7 3 CYS J  70  PHE J  73  0                                        
SHEET    2 AD7 3 ALA J 131  PHE J 136 -1  O  LEU J 132   N  ALA J  72           
SHEET    3 AD7 3 PRO J 142  GLN J 146 -1  O  TYR J 145   N  ILE J 133           
SHEET    1 AD8 3 ALA K  37  GLN K  41  0                                        
SHEET    2 AD8 3 VAL K  46  GLU K  51 -1  O  ALA K  49   N  ILE K  38           
SHEET    3 AD8 3 ILE K 215  LEU K 217 -1  O  GLU K 216   N  VAL K  50           
SHEET    1 AD9 4 CYS K  76  ALA K  77  0                                        
SHEET    2 AD9 4 LEU K 141  PHE K 143 -1  O  LEU K 142   N  ALA K  77           
SHEET    3 AD9 4 PHE K 154  MET K 156 -1  O  PHE K 154   N  PHE K 143           
SHEET    4 AD9 4 VAL K 163  GLN K 164 -1  O  VAL K 163   N  HIS K 155           
SHEET    1 AE1 2 VAL K 146  ASP K 147  0                                        
SHEET    2 AE1 2 GLY K 150  PRO K 151 -1  O  GLY K 150   N  ASP K 147           
SHEET    1 AE2 5 ALA L 158  ILE L 161  0                                        
SHEET    2 AE2 5 THR L  35  LYS L  39 -1  N  GLY L  37   O  MET L 159           
SHEET    3 AE2 5 ALA L  44  LEU L  49 -1  O  VAL L  47   N  VAL L  36           
SHEET    4 AE2 5 VAL L 210  VAL L 215 -1  O  GLY L 213   N  LEU L  46           
SHEET    5 AE2 5 THR L 222  ASP L 225 -1  O  TYR L 224   N  ILE L 212           
SHEET    1 AE3 5 LEU L  64  HIS L  65  0                                        
SHEET    2 AE3 5 GLY L  71  ILE L  72 -1  O  ILE L  72   N  LEU L  64           
SHEET    3 AE3 5 ILE L 134  ASP L 138 -1  O  ALA L 135   N  GLY L  71           
SHEET    4 AE3 5 GLY L 141  GLN L 146 -1  O  PHE L 145   N  ILE L 134           
SHEET    5 AE3 5 PHE L 154  CYS L 156 -1  O  CYS L 156   N  ILE L 144           
SHEET    1 AE4 4 GLY M 162  ILE M 165  0                                        
SHEET    2 AE4 4 ALA M  36  CYS M  41 -1  N  ALA M  36   O  ILE M 165           
SHEET    3 AE4 4 GLY M  44  VAL M  53 -1  O  GLY M  44   N  CYS M  41           
SHEET    4 AE4 4 ALA M 208  GLU M 212 -1  O  GLU M 210   N  LYS M  51           
SHEET    1 AE5 5 GLY M 162  ILE M 165  0                                        
SHEET    2 AE5 5 ALA M  36  CYS M  41 -1  N  ALA M  36   O  ILE M 165           
SHEET    3 AE5 5 GLY M  44  VAL M  53 -1  O  GLY M  44   N  CYS M  41           
SHEET    4 AE5 5 SER M 214  GLY M 217 -1  O  VAL M 216   N  VAL M  45           
SHEET    5 AE5 5 GLU M 225  ILE M 226 -1  O  GLU M 225   N  TRP M 215           
SHEET    1 AE6 4 VAL M  73  GLY M  79  0                                        
SHEET    2 AE6 4 CYS M 133  SER M 141 -1  O  SER M 134   N  ALA M  78           
SHEET    3 AE6 4 GLY M 145  ILE M 151 -1  O  GLY M 145   N  SER M 141           
SHEET    4 AE6 4 SER M 157  GLY M 159 -1  O  TYR M 158   N  MET M 150           
SHEET    1 AE7 5 PHE N 125  GLY N 128  0                                        
SHEET    2 AE7 5 ILE N   3  GLN N   7 -1  N  ALA N   5   O  ALA N 126           
SHEET    3 AE7 5 VAL N  12  ALA N  16 -1  O  VAL N  13   N  VAL N   6           
SHEET    4 AE7 5 ILE N 174  ILE N 179 -1  O  ARG N 175   N  ALA N  16           
SHEET    5 AE7 5 GLU N 185  LEU N 189 -1  O  GLU N 185   N  ALA N 178           
SHEET    1 AE8 2 THR N  20  THR N  22  0                                        
SHEET    2 AE8 2 TYR N  25  ASN N  28 -1  O  TYR N  25   N  THR N  22           
SHEET    1 AE9 5 LEU N  34  PRO N  36  0                                        
SHEET    2 AE9 5 ILE N  41  CYS N  44 -1  O  CYS N  43   N  THR N  35           
SHEET    3 AE9 5 ILE N  99  GLY N 102 -1  O  ALA N 101   N  PHE N  42           
SHEET    4 AE9 5 GLN N 110  SER N 113 -1  O  TYR N 112   N  ILE N 100           
SHEET    5 AE9 5 VAL N 121  ARG N 122 -1  O  VAL N 121   N  SER N 113           
SHEET    1 AF1 5 TYR O 124  GLY O 128  0                                        
SHEET    2 AF1 5 THR O   2  VAL O   7 -1  N  ILE O   3   O  MET O 127           
SHEET    3 AF1 5 ILE O  12  ASP O  17 -1  O  VAL O  13   N  VAL O   6           
SHEET    4 AF1 5 ILE O 173  ILE O 178 -1  O  ASP O 174   N  ALA O  16           
SHEET    5 AF1 5 LEU O 183  THR O 190 -1  O  ASP O 184   N  VAL O 177           
SHEET    1 AF2 2 ALA O  20  GLU O  22  0                                        
SHEET    2 AF2 2 VAL O  25  ASP O  28 -1  O  VAL O  25   N  GLU O  22           
SHEET    1 AF3 5 HIS O  35  PHE O  36  0                                        
SHEET    2 AF3 5 TYR O  42  ALA O  46 -1  O  CYS O  43   N  HIS O  35           
SHEET    3 AF3 5 ALA O  97  ASP O 104 -1  O  GLY O 101   N  TYR O  42           
SHEET    4 AF3 5 GLY O 107  ILE O 113 -1  O  TYR O 111   N  LEU O 100           
SHEET    5 AF3 5 THR O 119  LYS O 121 -1  O  ASP O 120   N  SER O 112           
SHEET    1 AF4 3 VAL O 211  THR O 213  0                                        
SHEET    2 AF4 3 LYS P 194  LEU P 200 -1  O  THR P 199   N  LEU O 212           
SHEET    3 AF4 3 ILE O 216  PRO O 218 -1  N  THR O 217   O  ILE P 195           
SHEET    1 AF5 6 VAL O 211  THR O 213  0                                        
SHEET    2 AF5 6 LYS P 194  LEU P 200 -1  O  THR P 199   N  LEU O 212           
SHEET    3 AF5 6 VAL P 185  ILE P 190 -1  N  VAL P 187   O  ARG P 198           
SHEET    4 AF5 6 VAL P  20  ASP P  25 -1  N  ILE P  22   O  HIS P 188           
SHEET    5 AF5 6 ALA P  10  LYS P  15 -1  N  MET P  12   O  ALA P  23           
SHEET    6 AF5 6 PHE P 136  GLY P 140 -1  O  VAL P 137   N  ALA P  13           
SHEET    1 AF6 2 PHE P  28  ILE P  30  0                                        
SHEET    2 AF6 2 GLN P  33  THR P  36 -1  O  VAL P  35   N  PHE P  28           
SHEET    1 AF7 4 ILE P  42  PRO P  44  0                                        
SHEET    2 AF7 4 LEU P  49  GLY P  52 -1  O  ILE P  51   N  PHE P  43           
SHEET    3 AF7 4 VAL P 108  LEU P 112 -1  O  VAL P 108   N  GLY P  52           
SHEET    4 AF7 4 PRO P 119  SER P 123 -1  O  CYS P 122   N  ILE P 109           
SHEET    1 AF8 3 VAL Q  13  ALA Q  16  0                                        
SHEET    2 AF8 3 ILE Q   5  GLN Q   8 -1  N  ILE Q   7   O  LEU Q  14           
SHEET    3 AF8 3 PHE Q 129  ALA Q 130 -1  O  ALA Q 130   N  GLY Q   6           
SHEET    1 AF9 3 ILE Q  42  LEU Q  44  0                                        
SHEET    2 AF9 3 LEU Q 104  ASP Q 108 -1  O  ALA Q 105   N  LEU Q  43           
SHEET    3 AF9 3 GLY Q 112  LEU Q 115 -1  O  ALA Q 114   N  GLY Q 106           
SHEET    1 AG1 2 THR Q 177  PHE Q 178  0                                        
SHEET    2 AG1 2 ILE Q 194  SER Q 195 -1  O  ILE Q 194   N  PHE Q 178           
SHEET    1 AG2 2 ARG Q 181  ILE Q 183  0                                        
SHEET    2 AG2 2 ILE Q 188  ASP Q 190 -1  O  HIS Q 189   N  ILE Q 182           
SHEET    1 AG3 5 THR R 125  GLY R 129  0                                        
SHEET    2 AG3 5 THR R   2  LYS R   7 -1  N  THR R   3   O  VAL R 128           
SHEET    3 AG3 5 VAL R  12  ALA R  16 -1  O  ILE R  13   N  PHE R   6           
SHEET    4 AG3 5 ALA R 173  VAL R 179 -1  O  TYR R 177   N  VAL R  14           
SHEET    5 AG3 5 ILE R 185  ASN R 191 -1  O  ILE R 185   N  HIS R 178           
SHEET    1 AG4 2 ALA R  20  ALA R  22  0                                        
SHEET    2 AG4 2 TYR R  25  SER R  28 -1  O  TYR R  25   N  ALA R  22           
SHEET    1 AG5 5 ILE R  35  ASN R  38  0                                        
SHEET    2 AG5 5 LEU R  41  GLY R  43 -1  O  GLY R  43   N  ILE R  35           
SHEET    3 AG5 5 MET R 100  GLY R 103 -1  O  CYS R 102   N  LEU R  42           
SHEET    4 AG5 5 LEU R 111  VAL R 114 -1  O  TYR R 112   N  ILE R 101           
SHEET    5 AG5 5 ARG R 120  SER R 122 -1  O  ILE R 121   N  TYR R 113           
SHEET    1 AG6 5 PHE S 135  ALA S 137  0                                        
SHEET    2 AG6 5 ILE S  12  ALA S  16 -1  N  ALA S  14   O  LYS S 136           
SHEET    3 AG6 5 ALA S  21  ASP S  26 -1  O  ALA S  24   N  LEU S  13           
SHEET    4 AG6 5 LEU S 193  THR S 199 -1  O  CYS S 196   N  VAL S  23           
SHEET    5 AG6 5 GLY S 202  VAL S 208 -1  O  ARG S 204   N  ILE S 197           
SHEET    1 AG7 5 TYR S  44  LYS S  45  0                                        
SHEET    2 AG7 5 THR S  50  GLY S  56 -1  O  ILE S  52   N  TYR S  44           
SHEET    3 AG7 5 VAL S 106  GLY S 112 -1  O  ILE S 109   N  GLY S  53           
SHEET    4 AG7 5 VAL S 121  SER S 123 -1  O  TYR S 122   N  ILE S 110           
SHEET    5 AG7 5 GLN S 131  ASP S 133 -1  O  ASP S 133   N  VAL S 121           
SHEET    1 AG8 5 SER T 136  ALA T 138  0                                        
SHEET    2 AG8 5 LEU T  12  PHE T  16 -1  N  GLY T  13   O  LEU T 137           
SHEET    3 AG8 5 GLY T  19  ASP T  25 -1  O  VAL T  21   N  VAL T  14           
SHEET    4 AG8 5 PHE T 187  VAL T 192 -1  O  ALA T 190   N  ILE T  22           
SHEET    5 AG8 5 GLU T 198  LEU T 203 -1  O  GLU T 200   N  ILE T 189           
SHEET    1 AG9 2 GLY T  28  TYR T  30  0                                        
SHEET    2 AG9 2 LEU T  33  PHE T  36 -1  O  LEU T  33   N  TYR T  30           
SHEET    1 AH1 5 ILE T  42  MET T  43  0                                        
SHEET    2 AH1 5 THR T  49  GLY T  55 -1  O  LEU T  51   N  MET T  43           
SHEET    3 AH1 5 ASN T 108  ALA T 116 -1  O  GLY T 113   N  MET T  50           
SHEET    4 AH1 5 GLU T 119  VAL T 125 -1  O  GLY T 123   N  ILE T 112           
SHEET    5 AH1 5 ALA T 131  GLU T 133 -1  O  TYR T 132   N  TYR T 124           
SHEET    1 AH2 5 ALA g 165  ALA g 167  0                                        
SHEET    2 AH2 5 SER g  39  ARG g  43 -1  N  ALA g  41   O  THR g 166           
SHEET    3 AH2 5 CYS g  47  GLN g  53 -1  O  VAL g  49   N  VAL g  42           
SHEET    4 AH2 5 ILE g 215  THR g 221 -1  O  GLY g 218   N  ILE g  50           
SHEET    5 AH2 5 ASN g 224  ILE g 229 -1  O  ARG g 228   N  VAL g 219           
SHEET    1 AH3 4 PHE g  70  LYS g  71  0                                        
SHEET    2 AH3 4 ILE g  76  MET g  80 -1  O  CYS g  78   N  PHE g  70           
SHEET    3 AH3 4 MET g 138  ASP g 144 -1  O  ILE g 141   N  GLY g  77           
SHEET    4 AH3 4 GLY g 148  CYS g 154 -1  O  CYS g 154   N  MET g 138           
SHEET    1 AH4 5 ALA h 160  MET h 163  0                                        
SHEET    2 AH4 5 SER h  35  ALA h  40 -1  N  GLY h  37   O  THR h 161           
SHEET    3 AH4 5 GLY h  43  GLU h  49 -1  O  VAL h  45   N  ILE h  38           
SHEET    4 AH4 5 ILE h 208  ASN h 214 -1  O  GLY h 211   N  LEU h  46           
SHEET    5 AH4 5 GLY h 217  ARG h 220 -1  O  GLY h 217   N  ASN h 214           
SHEET    1 AH5 4 ILE h  72  GLY h  78  0                                        
SHEET    2 AH5 4 VAL h 132  TRP h 139 -1  O  LEU h 135   N  VAL h  75           
SHEET    3 AH5 4 PRO h 144  SER h 149 -1  O  PHE h 147   N  ILE h 136           
SHEET    4 AH5 4 TYR h 155  ALA h 157 -1  O  PHE h 156   N  GLN h 148           
SHEET    1 AH6 4 CYS i  34  LEU i  35  0                                        
SHEET    2 AH6 4 ALA i  46  GLU i  48 -1  O  ALA i  46   N  LEU i  35           
SHEET    3 AH6 4 VAL i 211  THR i 217 -1  O  GLU i 212   N  ALA i  47           
SHEET    4 AH6 4 GLY i  42  VAL i  43 -1  N  VAL i  43   O  LEU i 216           
SHEET    1 AH7 4 CYS i  34  LEU i  35  0                                        
SHEET    2 AH7 4 ALA i  46  GLU i  48 -1  O  ALA i  46   N  LEU i  35           
SHEET    3 AH7 4 VAL i 211  THR i 217 -1  O  GLU i 212   N  ALA i  47           
SHEET    4 AH7 4 VAL i 224  VAL i 227 -1  O  VAL i 224   N  THR i 217           
SHEET    1 AH8 4 TYR i  66  LYS i  67  0                                        
SHEET    2 AH8 4 MET i  72  CYS i  74 -1  O  CYS i  74   N  TYR i  66           
SHEET    3 AH8 4 LEU i 135  TRP i 139 -1  O  ILE i 137   N  ALA i  73           
SHEET    4 AH8 4 PHE i 145  GLN i 149 -1  O  GLN i 146   N  GLY i 138           
SHEET    1 AH9 4 ALA j  32  VAL j  35  0                                        
SHEET    2 AH9 4 VAL j  41  VAL j  45 -1  O  GLY j  44   N  VAL j  33           
SHEET    3 AH9 4 GLU j 207  MET j 211 -1  O  ALA j 209   N  LEU j  43           
SHEET    4 AH9 4 LYS j 218  ILE j 219 -1  O  LYS j 218   N  VAL j 210           
SHEET    1 AI1 4 VAL j  69  ALA j  72  0                                        
SHEET    2 AI1 4 LEU j 132  PHE j 136 -1  O  LEU j 132   N  ALA j  72           
SHEET    3 AI1 4 PRO j 142  GLN j 146 -1  O  TYR j 145   N  ILE j 133           
SHEET    4 AI1 4 HIS j 154  ALA j 155 -1  O  HIS j 154   N  GLN j 146           
SHEET    1 AI2 4 ALA k 167  ALA k 169  0                                        
SHEET    2 AI2 4 ALA k  37  ILE k  40 -1  N  GLY k  39   O  ARG k 168           
SHEET    3 AI2 4 CYS k  47  GLU k  51 -1  O  CYS k  47   N  ILE k  40           
SHEET    4 AI2 4 ILE k 215  LEU k 217 -1  O  GLU k 216   N  VAL k  50           
SHEET    1 AI3 4 CYS k  76  ALA k  77  0                                        
SHEET    2 AI3 4 LEU k 141  ASP k 147 -1  O  LEU k 142   N  ALA k  77           
SHEET    3 AI3 4 GLY k 150  MET k 156 -1  O  PHE k 154   N  PHE k 143           
SHEET    4 AI3 4 VAL k 163  GLN k 164 -1  O  VAL k 163   N  HIS k 155           
SHEET    1 AI4 5 ALA l 158  ILE l 161  0                                        
SHEET    2 AI4 5 THR l  35  LYS l  39 -1  N  GLY l  37   O  MET l 159           
SHEET    3 AI4 5 HIS l  43  LEU l  49 -1  O  VAL l  47   N  VAL l  36           
SHEET    4 AI4 5 VAL l 210  GLY l 216 -1  O  VAL l 215   N  ALA l  44           
SHEET    5 AI4 5 THR l 222  ILE l 223 -1  O  THR l 222   N  ILE l 214           
SHEET    1 AI5 5 LEU l  64  HIS l  65  0                                        
SHEET    2 AI5 5 GLY l  71  SER l  73 -1  O  ILE l  72   N  LEU l  64           
SHEET    3 AI5 5 LEU l 133  ASP l 138 -1  O  ALA l 135   N  GLY l  71           
SHEET    4 AI5 5 GLY l 141  GLN l 146 -1  O  PHE l 145   N  ILE l 134           
SHEET    5 AI5 5 PHE l 154  CYS l 156 -1  O  CYS l 156   N  ILE l 144           
SHEET    1 AI6 5 GLY m 162  ILE m 165  0                                        
SHEET    2 AI6 5 ALA m  36  ARG m  40 -1  N  ALA m  36   O  ILE m 165           
SHEET    3 AI6 5 GLY m  44  VAL m  53 -1  O  GLY m  48   N  ILE m  37           
SHEET    4 AI6 5 ALA m 208  GLY m 217 -1  O  GLU m 210   N  LYS m  51           
SHEET    5 AI6 5 HIS m 224  ILE m 226 -1  O  GLU m 225   N  TRP m 215           
SHEET    1 AI7 4 GLY m  74  ALA m  76  0                                        
SHEET    2 AI7 4 PHE m 135  TYR m 140 -1  O  GLY m 138   N  GLY m  74           
SHEET    3 AI7 4 ALA m 146  ILE m 151 -1  O  TYR m 149   N  LEU m 137           
SHEET    4 AI7 4 SER m 157  GLY m 159 -1  O  TYR m 158   N  MET m 150           
SHEET    1 AI8 5 PHE n 125  GLY n 128  0                                        
SHEET    2 AI8 5 ILE n   3  GLN n   7 -1  N  ALA n   5   O  ALA n 126           
SHEET    3 AI8 5 VAL n  12  ALA n  16 -1  O  VAL n  13   N  VAL n   6           
SHEET    4 AI8 5 ILE n 174  ALA n 180 -1  O  ILE n 179   N  VAL n  12           
SHEET    5 AI8 5 GLY n 183  VAL n 184 -1  O  GLY n 183   N  ALA n 180           
SHEET    1 AI9 5 PHE n 125  GLY n 128  0                                        
SHEET    2 AI9 5 ILE n   3  GLN n   7 -1  N  ALA n   5   O  ALA n 126           
SHEET    3 AI9 5 VAL n  12  ALA n  16 -1  O  VAL n  13   N  VAL n   6           
SHEET    4 AI9 5 ILE n 174  ALA n 180 -1  O  ILE n 179   N  VAL n  12           
SHEET    5 AI9 5 GLN n 187  LEU n 189 -1  O  GLN n 187   N  LEU n 176           
SHEET    1 AJ1 2 THR n  20  THR n  22  0                                        
SHEET    2 AJ1 2 TYR n  25  ASN n  28 -1  O  ASN n  28   N  THR n  20           
SHEET    1 AJ2 5 THR n  35  PRO n  36  0                                        
SHEET    2 AJ2 5 ILE n  41  CYS n  44 -1  O  CYS n  43   N  THR n  35           
SHEET    3 AJ2 5 ILE n  99  ASP n 104 -1  O  ILE n  99   N  CYS n  44           
SHEET    4 AJ2 5 GLY n 108  SER n 113 -1  O  TYR n 112   N  ILE n 100           
SHEET    5 AJ2 5 VAL n 121  ARG n 122 -1  O  VAL n 121   N  SER n 113           
SHEET    1 AJ3 5 TYR o 124  GLY o 128  0                                        
SHEET    2 AJ3 5 THR o   2  VAL o   7 -1  N  ILE o   3   O  MET o 127           
SHEET    3 AJ3 5 ILE o  12  ALA o  16 -1  O  GLY o  15   N  ALA o   4           
SHEET    4 AJ3 5 ILE o 173  ILE o 178 -1  O  CYS o 176   N  LEU o  14           
SHEET    5 AJ3 5 ASP o 184  THR o 190 -1  O  TYR o 189   N  ILE o 173           
SHEET    1 AJ4 2 ALA o  20  GLU o  22  0                                        
SHEET    2 AJ4 2 VAL o  25  ASP o  28 -1  O  VAL o  25   N  GLU o  22           
SHEET    1 AJ5 5 HIS o  35  PHE o  36  0                                        
SHEET    2 AJ5 5 ILE o  41  GLY o  47 -1  O  CYS o  43   N  HIS o  35           
SHEET    3 AJ5 5 ALA o  96  VAL o 103 -1  O  VAL o  99   N  CYS o  44           
SHEET    4 AJ5 5 PRO o 108  ILE o 113 -1  O  TYR o 111   N  LEU o 100           
SHEET    5 AJ5 5 THR o 119  ASP o 120 -1  O  ASP o 120   N  SER o 112           
SHEET    1 AJ6 3 VAL o 211  THR o 213  0                                        
SHEET    2 AJ6 3 LYS p 194  LEU p 200 -1  O  THR p 199   N  LEU o 212           
SHEET    3 AJ6 3 ILE o 216  PRO o 218 -1  N  THR o 217   O  ILE p 195           
SHEET    1 AJ7 6 VAL o 211  THR o 213  0                                        
SHEET    2 AJ7 6 LYS p 194  LEU p 200 -1  O  THR p 199   N  LEU o 212           
SHEET    3 AJ7 6 VAL p 185  ILE p 190 -1  N  VAL p 187   O  ARG p 198           
SHEET    4 AJ7 6 VAL p  20  ASP p  25 -1  N  ILE p  22   O  HIS p 188           
SHEET    5 AJ7 6 ALA p  10  LYS p  15 -1  N  MET p  12   O  ALA p  23           
SHEET    6 AJ7 6 PHE p 136  GLY p 140 -1  O  SER p 139   N  VAL p  11           
SHEET    1 AJ8 2 PHE p  28  ILE p  30  0                                        
SHEET    2 AJ8 2 GLN p  33  THR p  36 -1  O  VAL p  35   N  PHE p  28           
SHEET    1 AJ9 5 PHE p  43  PRO p  44  0                                        
SHEET    2 AJ9 5 LEU p  49  GLY p  52 -1  O  ILE p  51   N  PHE p  43           
SHEET    3 AJ9 5 VAL p 108  LEU p 112 -1  O  VAL p 108   N  GLY p  52           
SHEET    4 AJ9 5 PRO p 119  SER p 123 -1  O  CYS p 122   N  ILE p 109           
SHEET    5 AJ9 5 MET p 131  VAL p 132 -1  O  MET p 131   N  SER p 123           
SHEET    1 AK1 3 VAL q  13  ALA q  16  0                                        
SHEET    2 AK1 3 VAL q 180  ASP q 184 -1  O  ARG q 181   N  VAL q  15           
SHEET    3 AK1 3 GLY q 187  ASP q 190 -1  O  GLY q 187   N  ASP q 184           
SHEET    1 AK2 4 PHE q  36  LYS q  37  0                                        
SHEET    2 AK2 4 ILE q  42  LEU q  44 -1  O  LEU q  44   N  PHE q  36           
SHEET    3 AK2 4 LEU q 104  ASP q 108 -1  O  ALA q 105   N  LEU q  43           
SHEET    4 AK2 4 GLY q 112  LEU q 115 -1  O  ALA q 114   N  GLY q 106           
SHEET    1 AK3 2 THR q 177  PHE q 178  0                                        
SHEET    2 AK3 2 ILE q 194  SER q 195 -1  O  ILE q 194   N  PHE q 178           
SHEET    1 AK4 5 THR r 125  GLY r 129  0                                        
SHEET    2 AK4 5 THR r   2  PHE r   8 -1  N  THR r   3   O  VAL r 128           
SHEET    3 AK4 5 GLY r  11  ALA r  16 -1  O  GLY r  11   N  PHE r   8           
SHEET    4 AK4 5 ALA r 173  VAL r 179 -1  O  TYR r 177   N  VAL r  14           
SHEET    5 AK4 5 TRP r 184  ASN r 191 -1  O  ILE r 185   N  HIS r 178           
SHEET    1 AK5 2 ALA r  20  ALA r  22  0                                        
SHEET    2 AK5 2 TYR r  25  SER r  28 -1  O  TYR r  25   N  ALA r  22           
SHEET    1 AK6 4 LEU r  41  GLY r  43  0                                        
SHEET    2 AK6 4 MET r 100  ASP r 105 -1  O  CYS r 102   N  LEU r  42           
SHEET    3 AK6 4 GLY r 108  VAL r 114 -1  O  GLY r 108   N  ASP r 105           
SHEET    4 AK6 4 ARG r 120  ILE r 121 -1  O  ILE r 121   N  TYR r 113           
SHEET    1 AK7 5 PHE s 135  GLY s 139  0                                        
SHEET    2 AK7 5 THR s  11  ALA s  16 -1  N  ILE s  12   O  GLY s 138           
SHEET    3 AK7 5 ALA s  21  ASP s  26 -1  O  ALA s  24   N  LEU s  13           
SHEET    4 AK7 5 LEU s 193  THR s 199 -1  O  ARG s 194   N  SER s  25           
SHEET    5 AK7 5 GLY s 202  VAL s 208 -1  O  ARG s 204   N  ILE s 197           
SHEET    1 AK8 2 LEU s  29  GLU s  31  0                                        
SHEET    2 AK8 2 SER s  34  THR s  37 -1  O  SER s  34   N  GLU s  31           
SHEET    1 AK9 5 CYS s  43  LYS s  45  0                                        
SHEET    2 AK9 5 THR s  50  GLY s  56 -1  O  ILE s  52   N  TYR s  44           
SHEET    3 AK9 5 VAL s 106  LEU s 113 -1  O  ILE s 109   N  GLY s  53           
SHEET    4 AK9 5 GLY s 119  SER s 123 -1  O  TYR s 122   N  ILE s 110           
SHEET    5 AK9 5 GLN s 131  ASP s 133 -1  O  ASP s 133   N  VAL s 121           
SHEET    1 AL1 2 THR t   7  GLY t   8  0                                        
SHEET    2 AL1 2 GLY t  55  ASP t  56 -1  O  GLY t  55   N  GLY t   8           
SHEET    1 AL2 5 SER t 136  ALA t 138  0                                        
SHEET    2 AL2 5 VAL t  11  PHE t  16 -1  N  GLY t  13   O  LEU t 137           
SHEET    3 AL2 5 GLY t  19  ASP t  25 -1  O  ALA t  23   N  LEU t  12           
SHEET    4 AL2 5 PHE t 187  THR t 193 -1  O  ALA t 190   N  ILE t  22           
SHEET    5 AL2 5 GLY t 196  LEU t 203 -1  O  GLU t 200   N  ILE t 189           
SHEET    1 AL3 2 GLY t  28  TYR t  30  0                                        
SHEET    2 AL3 2 LEU t  33  PHE t  36 -1  O  PHE t  36   N  GLY t  28           
SHEET    1 AL4 5 ILE t  42  MET t  43  0                                        
SHEET    2 AL4 5 THR t  49  ALA t  53 -1  O  LEU t  51   N  MET t  43           
SHEET    3 AL4 5 MET t 110  ALA t 116 -1  O  GLY t 113   N  MET t  50           
SHEET    4 AL4 5 GLU t 119  VAL t 125 -1  O  PHE t 121   N  GLY t 114           
SHEET    5 AL4 5 ALA t 131  GLU t 133 -1  O  TYR t 132   N  TYR t 124           
SSBOND   1 CYS M   41    CYS M  186                          1555   1555  2.03  
SSBOND   2 CYS m   41    CYS m  186                          1555   1555  2.02  
CISPEP   1 LEU U  118    PRO U  119          0       -14.76                     
CISPEP   2 ASP U  172    VAL U  173          0        -2.58                     
CISPEP   3 LYS U  429    ASP U  430          0         8.26                     
CISPEP   4 ASN U  470    ASP U  471          0         0.00                     
CISPEP   5 LYS U  842    GLU U  843          0        15.85                     
CISPEP   6 ALA V   56    ALA V   57          0        17.38                     
CISPEP   7 ALA V   59    ALA V   60          0        13.86                     
CISPEP   8 LYS V   76    GLU V   77          0        -7.02                     
CISPEP   9 ALA V   97    LEU V   98          0       -27.94                     
CISPEP  10 LEU V   98    ARG V   99          0       -10.10                     
CISPEP  11 GLU V  142    ALA V  143          0         3.22                     
CISPEP  12 ASP V  144    LEU V  145          0       -17.81                     
CISPEP  13 MET V  192    GLN V  193          0        -4.39                     
CISPEP  14 GLN V  193    LYS V  194          0         9.42                     
CISPEP  15 LYS V  194    ILE V  195          0         0.17                     
CISPEP  16 THR V  239    LEU V  240          0        -5.05                     
CISPEP  17 SER V  262    LEU V  263          0        10.65                     
CISPEP  18 LYS V  273    SER V  274          0         2.60                     
CISPEP  19 VAL V  275    PHE V  276          0        10.29                     
CISPEP  20 PRO V  277    GLU V  278          0        -9.54                     
CISPEP  21 ALA V  280    ASN V  281          0        -1.66                     
CISPEP  22 PRO V  317    GLN V  318          0       -26.73                     
CISPEP  23 THR V  320    ALA V  321          0        21.36                     
CISPEP  24 ALA V  321    VAL V  322          0        -9.25                     
CISPEP  25 LYS V  455    GLY V  456          0       -10.19                     
CISPEP  26 GLN W  257    ALA W  258          0         6.71                     
CISPEP  27 GLY W  331    SER W  332          0         0.59                     
CISPEP  28 TYR W  370    THR W  371          0         7.70                     
CISPEP  29 GLN W  416    ARG W  417          0       -28.19                     
CISPEP  30 PRO W  418    LYS W  419          0        10.21                     
CISPEP  31 PRO W  421    ASN W  422          0       -16.94                     
CISPEP  32 GLU Y  170    GLY Y  171          0       -15.40                     
CISPEP  33 GLY Y  324    VAL Y  325          0         6.42                     
CISPEP  34 ASN Y  357    ARG Y  358          0         4.71                     
CISPEP  35 ILE Y  387    ASN Y  388          0        -0.71                     
CISPEP  36 GLY Z   30    ASN Z   31          0        -1.02                     
CISPEP  37 LYS Z   63    ASP Z   64          0         7.12                     
CISPEP  38 GLY Z   98    PRO Z   99          0         0.84                     
CISPEP  39 ASP Z  130    LEU Z  131          0       -12.02                     
CISPEP  40 ASP Z  181    THR Z  182          0        -2.93                     
CISPEP  41 THR Z  182    THR Z  183          0        -6.16                     
CISPEP  42 LYS Z  219    LEU Z  220          0        26.30                     
CISPEP  43 LEU Z  220    PRO Z  221          0         0.01                     
CISPEP  44 ASN Z  223    HIS Z  224          0         6.09                     
CISPEP  45 PRO Z  238    ASP Z  239          0       -15.54                     
CISPEP  46 SER Z  241    LEU Z  242          0        -3.92                     
CISPEP  47 LEU Z  242    GLN Z  243          0         9.60                     
CISPEP  48 PHE a   50    ALA a   51          0        -4.46                     
CISPEP  49 ILE a  125    GLY a  126          0       -10.03                     
CISPEP  50 ASN a  144    LEU a  145          0        -7.39                     
CISPEP  51 ILE a  166    GLY a  167          0         3.84                     
CISPEP  52 GLY a  243    ASN a  244          0        -5.11                     
CISPEP  53 VAL a  245    GLU a  246          0        -4.08                     
CISPEP  54 ALA a  286    ASN a  287          0       -27.36                     
CISPEP  55 ASN a  287    HIS a  288          0         2.73                     
CISPEP  56 LEU b   22    PRO b   23          0       -11.52                     
CISPEP  57 LYS b  163    ASP b  164          0        -4.50                     
CISPEP  58 ASP b  164    GLY b  165          0        -2.55                     
CISPEP  59 THR b  166    GLY b  167          0         2.11                     
CISPEP  60 VAL c   49    PRO c   50          0        -4.08                     
CISPEP  61 PRO c  174    ARG c  175          0         2.96                     
CISPEP  62 LYS c  186    PRO c  187          0         5.81                     
CISPEP  63 LYS c  209    ASN c  210          0         0.57                     
CISPEP  64 ASN c  274    VAL c  275          0        -5.71                     
CISPEP  65 GLN c  278    ASP c  279          0        12.15                     
CISPEP  66 ASP c  279    PRO c  280          0        -3.33                     
CISPEP  67 ARG c  282    HIS c  283          0        -5.19                     
CISPEP  68 LEU d   36    PRO d   37          0        -6.96                     
CISPEP  69 GLY d   40    THR d   41          0        -0.54                     
CISPEP  70 GLU d  145    GLY d  146          0        -4.74                     
CISPEP  71 SER d  147    TYR d  148          0         3.21                     
CISPEP  72 PRO d  159    ALA d  160          0        -3.31                     
CISPEP  73 ALA d  160    GLU d  161          0        -2.72                     
CISPEP  74 GLU d  183    LYS d  184          0         0.34                     
CISPEP  75 LYS d  184    ALA d  185          0         0.22                     
CISPEP  76 GLY d  214    TRP d  215          0        23.29                     
CISPEP  77 PHE d  225    ALA d  226          0        -1.06                     
CISPEP  78 ALA d  226    SER d  227          0       -11.21                     
CISPEP  79 GLN d  228    GLN d  229          0         9.55                     
CISPEP  80 GLU d  233    ASP d  234          0         0.73                     
CISPEP  81 ILE d  256    VAL d  257          0         5.23                     
CISPEP  82 MET e    1    SER e    2          0        -1.80                     
CISPEP  83 ALA e   58    GLU e   59          0        -9.31                     
CISPEP  84 ARG A   97    CYS A   98          0         8.49                     
CISPEP  85 GLY A  205    ILE A  206          0        10.09                     
CISPEP  86 GLY A  219    THR A  220          0       -14.20                     
CISPEP  87 ALA A  283    ARG A  284          0         1.30                     
CISPEP  88 GLY A  288    ALA A  289          0        -0.85                     
CISPEP  89 GLY A  290    GLY A  291          0        12.39                     
CISPEP  90 ASP A  310    PRO A  311          0       -18.46                     
CISPEP  91 PRO A  311    ARG A  312          0        -4.60                     
CISPEP  92 ARG A  312    GLY A  313          0        -4.74                     
CISPEP  93 ASP A  325    THR A  326          0        11.81                     
CISPEP  94 PHE A  343    SER A  344          0        18.14                     
CISPEP  95 SER A  344    LEU A  345          0        13.66                     
CISPEP  96 GLY B  104    THR B  105          0       -13.16                     
CISPEP  97 SER B  126    VAL B  127          0        -6.91                     
CISPEP  98 VAL B  139    ASP B  140          0         1.46                     
CISPEP  99 LYS B  155    VAL B  156          0       -16.11                     
CISPEP 100 ASP B  166    THR B  167          0        -8.56                     
CISPEP 101 LYS B  175    VAL B  176          0         4.02                     
CISPEP 102 VAL B  176    GLU B  177          0         0.56                     
CISPEP 103 GLU B  177    LYS B  178          0        12.33                     
CISPEP 104 PRO B  227    PRO B  228          0       -28.72                     
CISPEP 105 GLY B  261    ASP B  262          0        -0.69                     
CISPEP 106 ALA B  278    PRO B  279          0        -1.36                     
CISPEP 107 GLY B  300    GLY B  301          0        -8.27                     
CISPEP 108 ASP B  317    GLY B  318          0         5.37                     
CISPEP 109 PHE B  319    ASP B  320          0       -24.48                     
CISPEP 110 ASP B  324    VAL B  325          0         0.52                     
CISPEP 111 GLY B  345    ARG B  346          0        -9.41                     
CISPEP 112 GLU C   13    GLY C   14          0        -0.83                     
CISPEP 113 VAL C   99    ASP C  100          0        18.39                     
CISPEP 114 PRO C  192    GLY C  193          0        16.95                     
CISPEP 115 SER C  215    GLY C  216          0        13.34                     
CISPEP 116 ALA C  242    PRO C  243          0        -0.35                     
CISPEP 117 ASP C  249    GLU C  250          0        -6.88                     
CISPEP 118 ALA C  285    THR C  286          0       -10.77                     
CISPEP 119 ARG C  310    ILE C  311          0       -11.61                     
CISPEP 120 ILE D   82    GLN D   83          0        -2.53                     
CISPEP 121 SER D   84    ILE D   85          0        -2.25                     
CISPEP 122 ILE D   85    PRO D   86          0       -13.75                     
CISPEP 123 PRO D  144    PRO D  145          0       -23.30                     
CISPEP 124 PRO D  145    GLU D  146          0       -13.41                     
CISPEP 125 LYS D  159    PRO D  160          0         3.63                     
CISPEP 126 PRO D  207    PRO D  208          0       -10.34                     
CISPEP 127 PRO D  208    GLY D  209          0         2.33                     
CISPEP 128 ALA D  258    PRO D  259          0         1.77                     
CISPEP 129 ASP D  300    GLN D  301          0         0.60                     
CISPEP 130 VAL D  303    ASN D  304          0       -14.39                     
CISPEP 131 SER D  371    GLY D  372          0         5.51                     
CISPEP 132 ALA D  373    ASP D  374          0       -20.39                     
CISPEP 133 GLU D  389    ASN D  390          0        17.90                     
CISPEP 134 VAL D  406    ILE D  407          0        -1.23                     
CISPEP 135 LYS D  408    LYS D  409          0        -1.99                     
CISPEP 136 ASP D  410    GLU D  411          0        -1.43                     
CISPEP 137 GLU D  411    GLN D  412          0        -0.27                     
CISPEP 138 GLY E  128    ASN E  129          0         1.19                     
CISPEP 139 GLY E  137    LEU E  138          0         1.03                     
CISPEP 140 GLY E  174    PRO E  175          0       -10.94                     
CISPEP 141 GLN E  226    PRO E  227          0         3.23                     
CISPEP 142 GLY E  266    PHE E  267          0        10.59                     
CISPEP 143 LYS F   84    THR F   85          0         3.28                     
CISPEP 144 ASN F  102    ASP F  103          0        -1.69                     
CISPEP 145 ILE F  137    GLY F  138          0         9.00                     
CISPEP 146 GLY F  138    LEU F  139          0        10.12                     
CISPEP 147 LYS F  144    LEU F  145          0        -0.22                     
CISPEP 148 PRO F  165    THR F  166          0        -2.48                     
CISPEP 149 TYR F  168    ASP F  169          0       -21.54                     
CISPEP 150 PRO F  229    GLY F  230          0        -6.61                     
CISPEP 151 GLY F  230    THR F  231          0        14.51                     
CISPEP 152 ALA F  279    PRO F  280          0        -3.55                     
CISPEP 153 SER F  298    GLU F  299          0        12.82                     
CISPEP 154 GLU F  299    LYS F  300          0        -9.97                     
CISPEP 155 GLN F  428    ALA F  429          0        12.63                     
CISPEP 156 LYS F  431    LYS F  432          0       -20.93                     
CISPEP 157 ILE I  164    GLY I  165          0        -9.34                     
CISPEP 158 MET I  184    THR I  185          0         5.39                     
CISPEP 159 ASN I  220    GLY I  221          0        -6.51                     
CISPEP 160 ALA J  180    ILE J  181          0         5.40                     
CISPEP 161 GLU K   18    GLY K   19          0         8.29                     
CISPEP 162 ASN K  225    PHE K  226          0        -5.76                     
CISPEP 163 PHE K  226    HIS K  227          0         5.43                     
CISPEP 164 LYS g  184    LYS g  185          0        19.69                     
CISPEP 165 ALA h  231    ALA h  232          0        20.84                     
CISPEP 166 ILE i  164    GLY i  165          0       -11.39                     
CISPEP 167 MET i  184    THR i  185          0        21.55                     
CISPEP 168 ASN i  220    GLY i  221          0        -5.27                     
CISPEP 169 ALA j  180    ILE j  181          0        12.86                     
CISPEP 170 GLU k   18    GLY k   19          0        -4.00                     
CISPEP 171 ASN k  225    PHE k  226          0        -9.14                     
CISPEP 172 PHE k  226    HIS k  227          0         0.10                     
CISPEP 173 LYS m   56    LEU m   57          0       -17.94                     
CISPEP 174 ARG o  187    PRO o  188          0        -4.83                     
SITE     1 AC1  4 HIS c 113  HIS c 115  SER c 123  ASP c 126                    
CRYST1    1.000    1.000    1.000  90.00  90.00  90.00 P 1           1          
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      1.000000  0.000000  0.000000        0.00000                         
SCALE2      0.000000  1.000000  0.000000        0.00000                         
SCALE3      0.000000  0.000000  1.000000        0.00000                         
(ATOM LINES ARE NOT SHOWN.)
END                                                                             
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