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Database: PDB
Entry: 5WP6
LinkDB: 5WP6
Original site: 5WP6 
HEADER    MEMBRANE PROTEIN                        03-AUG-17   5WP6              
TITLE     CRYO-EM STRUCTURE OF A HUMAN TRPM4 CHANNEL IN COMPLEX WITH CALCIUM AND
TITLE    2 DECAVANADATE                                                         
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M    
COMPND   3 MEMBER 4;                                                            
COMPND   4 CHAIN: A, B, C, D;                                                   
COMPND   5 SYNONYM: HTRPM4,CALCIUM-ACTIVATED NON-SELECTIVE CATION CHANNEL 1,LONG
COMPND   6 TRANSIENT RECEPTOR POTENTIAL CHANNEL 4,LTRPC4,MELASTATIN-4;          
COMPND   7 ENGINEERED: YES                                                      
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE   3 ORGANISM_COMMON: HUMAN;                                              
SOURCE   4 ORGANISM_TAXID: 9606;                                                
SOURCE   5 GENE: TRPM4, LTRPC4;                                                 
SOURCE   6 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE   7 EXPRESSION_SYSTEM_TAXID: 9606                                        
KEYWDS    ION CHANNEL, MEMBRANE PROTEIN                                         
EXPDTA    ELECTRON MICROSCOPY                                                   
AUTHOR    P.A.WINKLER,Y.HUANG,W.SUN,J.DU,W.LU                                   
REVDAT   3   27-DEC-17 5WP6    1       JRNL                                     
REVDAT   2   20-DEC-17 5WP6    1       JRNL                                     
REVDAT   1   13-DEC-17 5WP6    0                                                
JRNL        AUTH   P.A.WINKLER,Y.HUANG,W.SUN,J.DU,W.LU                          
JRNL        TITL   ELECTRON CRYO-MICROSCOPY STRUCTURE OF A HUMAN TRPM4 CHANNEL. 
JRNL        REF    NATURE                        V. 552   200 2017              
JRNL        REFN                   ESSN 1476-4687                               
JRNL        PMID   29211723                                                     
JRNL        DOI    10.1038/NATURE24674                                          
REMARK   2                                                                      
REMARK   2 RESOLUTION.    3.80 ANGSTROMS.                                       
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   SOFTWARE PACKAGES      : NULL                                      
REMARK   3   RECONSTRUCTION SCHEMA  : NULL                                      
REMARK   3                                                                      
REMARK   3 EM MAP-MODEL FITTING AND REFINEMENT                                  
REMARK   3   PDB ENTRY                    : NULL                                
REMARK   3   REFINEMENT SPACE             : NULL                                
REMARK   3   REFINEMENT PROTOCOL          : NULL                                
REMARK   3   REFINEMENT TARGET            : NULL                                
REMARK   3   OVERALL ANISOTROPIC B VALUE  : NULL                                
REMARK   3                                                                      
REMARK   3 FITTING PROCEDURE : NULL                                             
REMARK   3                                                                      
REMARK   3 EM IMAGE RECONSTRUCTION STATISTICS                                   
REMARK   3   NOMINAL PIXEL SIZE (ANGSTROMS)    : NULL                           
REMARK   3   ACTUAL PIXEL SIZE  (ANGSTROMS)    : NULL                           
REMARK   3   EFFECTIVE RESOLUTION (ANGSTROMS)  : 3.800                          
REMARK   3   NUMBER OF PARTICLES               : 121906                         
REMARK   3   CTF CORRECTION METHOD             : NONE                           
REMARK   3                                                                      
REMARK   3 EM RECONSTRUCTION MAGNIFICATION CALIBRATION: NULL                    
REMARK   3                                                                      
REMARK   3 OTHER DETAILS: NULL                                                  
REMARK   4                                                                      
REMARK   4 5WP6 COMPLIES WITH FORMAT V. 3.30, 13-JUL-11                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 18-AUG-17.                  
REMARK 100 THE DEPOSITION ID IS D_1000229385.                                   
REMARK 245                                                                      
REMARK 245 EXPERIMENTAL DETAILS                                                 
REMARK 245   RECONSTRUCTION METHOD          : SINGLE PARTICLE                   
REMARK 245   SPECIMEN TYPE                  : NULL                              
REMARK 245                                                                      
REMARK 245 ELECTRON MICROSCOPE SAMPLE                                           
REMARK 245   SAMPLE TYPE                    : PARTICLE                          
REMARK 245   PARTICLE TYPE                  : POINT                             
REMARK 245   NAME OF SAMPLE                 : TRPM4                             
REMARK 245   SAMPLE CONCENTRATION (MG ML-1) : NULL                              
REMARK 245   SAMPLE SUPPORT DETAILS         : NULL                              
REMARK 245   SAMPLE VITRIFICATION DETAILS   : NULL                              
REMARK 245   SAMPLE BUFFER                  : NULL                              
REMARK 245   PH                             : 8.00                              
REMARK 245   SAMPLE DETAILS                 : NULL                              
REMARK 245                                                                      
REMARK 245 DATA ACQUISITION                                                     
REMARK 245   DATE OF EXPERIMENT                : NULL                           
REMARK 245   NUMBER OF MICROGRAPHS-IMAGES      : NULL                           
REMARK 245   TEMPERATURE (KELVIN)              : NULL                           
REMARK 245   MICROSCOPE MODEL                  : FEI TITAN KRIOS                
REMARK 245   DETECTOR TYPE                     : GATAN K2 SUMMIT (4K X 4K)      
REMARK 245   MINIMUM DEFOCUS (NM)              : NULL                           
REMARK 245   MAXIMUM DEFOCUS (NM)              : NULL                           
REMARK 245   MINIMUM TILT ANGLE (DEGREES)      : NULL                           
REMARK 245   MAXIMUM TILT ANGLE (DEGREES)      : NULL                           
REMARK 245   NOMINAL CS                        : NULL                           
REMARK 245   IMAGING MODE                      : BRIGHT FIELD                   
REMARK 245   ELECTRON DOSE (ELECTRONS NM**-2)  : 54.00                          
REMARK 245   ILLUMINATION MODE                 : FLOOD BEAM                     
REMARK 245   NOMINAL MAGNIFICATION             : NULL                           
REMARK 245   CALIBRATED MAGNIFICATION          : NULL                           
REMARK 245   SOURCE                            : FIELD EMISSION GUN             
REMARK 245   ACCELERATION VOLTAGE (KV)         : 300                            
REMARK 245   IMAGING DETAILS                   : NULL                           
REMARK 247                                                                      
REMARK 247 ELECTRON MICROSCOPY                                                  
REMARK 247  THE COORDINATES IN THIS ENTRY WERE GENERATED FROM ELECTRON          
REMARK 247  MICROSCOPY DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE              
REMARK 247  THAT CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES           
REMARK 247  ON THESE RECORDS ARE MEANINGLESS EXCEPT FOR THE CALCULATION         
REMARK 247  OF THE STRUCTURE FACTORS.                                           
REMARK 300                                                                      
REMARK 300 BIOMOLECULE: 1                                                       
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM                
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN                  
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON               
REMARK 300 BURIED SURFACE AREA.                                                 
REMARK 350                                                                      
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN           
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE                
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS          
REMARK 350 GIVEN BELOW.  BOTH NON-CRYSTALLOGRAPHIC AND                          
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.                               
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 1                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TETRAMERIC                        
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B, C, D                            
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 465                                                                      
REMARK 465 MISSING RESIDUES                                                     
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE                       
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)                
REMARK 465                                                                      
REMARK 465   M RES C SSSEQI                                                     
REMARK 465     MET A     1                                                      
REMARK 465     VAL A     2                                                      
REMARK 465     VAL A     3                                                      
REMARK 465     PRO A     4                                                      
REMARK 465     GLU A     5                                                      
REMARK 465     LYS A     6                                                      
REMARK 465     THR A    21                                                      
REMARK 465     THR A    22                                                      
REMARK 465     PHE A    23                                                      
REMARK 465     ILE A    24                                                      
REMARK 465     VAL A    25                                                      
REMARK 465     ASP A    26                                                      
REMARK 465     SER A    27                                                      
REMARK 465     THR A    28                                                      
REMARK 465     ASP A    29                                                      
REMARK 465     PRO A    30                                                      
REMARK 465     GLY A    31                                                      
REMARK 465     GLY A    32                                                      
REMARK 465     THR A    33                                                      
REMARK 465     LEU A    34                                                      
REMARK 465     CYS A    35                                                      
REMARK 465     GLN A    36                                                      
REMARK 465     CYS A    37                                                      
REMARK 465     GLY A    38                                                      
REMARK 465     ARG A    39                                                      
REMARK 465     PRO A    40                                                      
REMARK 465     ARG A    41                                                      
REMARK 465     THR A    42                                                      
REMARK 465     ALA A    43                                                      
REMARK 465     HIS A    44                                                      
REMARK 465     PRO A    45                                                      
REMARK 465     ALA A    46                                                      
REMARK 465     VAL A    47                                                      
REMARK 465     ALA A    48                                                      
REMARK 465     MET A    49                                                      
REMARK 465     GLU A    50                                                      
REMARK 465     ASP A    51                                                      
REMARK 465     ALA A    52                                                      
REMARK 465     PHE A    53                                                      
REMARK 465     GLY A    54                                                      
REMARK 465     ALA A    55                                                      
REMARK 465     ALA A    56                                                      
REMARK 465     VAL A    57                                                      
REMARK 465     VAL A    58                                                      
REMARK 465     THR A    59                                                      
REMARK 465     VAL A    60                                                      
REMARK 465     TRP A    61                                                      
REMARK 465     ASP A    62                                                      
REMARK 465     SER A    63                                                      
REMARK 465     ASP A    64                                                      
REMARK 465     ALA A    65                                                      
REMARK 465     ASP A   216                                                      
REMARK 465     PRO A   217                                                      
REMARK 465     GLU A   218                                                      
REMARK 465     ASP A   219                                                      
REMARK 465     GLY A   220                                                      
REMARK 465     LEU A   319                                                      
REMARK 465     ALA A   320                                                      
REMARK 465     PRO A   321                                                      
REMARK 465     GLY A   322                                                      
REMARK 465     SER A   323                                                      
REMARK 465     GLY A   324                                                      
REMARK 465     GLY A   325                                                      
REMARK 465     ALA A   326                                                      
REMARK 465     SER A   388                                                      
REMARK 465     GLU A   389                                                      
REMARK 465     ALA A   390                                                      
REMARK 465     SER A   391                                                      
REMARK 465     ALA A   392                                                      
REMARK 465     SER A   481                                                      
REMARK 465     HIS A   482                                                      
REMARK 465     SER A   483                                                      
REMARK 465     ALA A   484                                                      
REMARK 465     GLY A   485                                                      
REMARK 465     THR A   486                                                      
REMARK 465     LYS A   487                                                      
REMARK 465     ALA A   488                                                      
REMARK 465     PRO A   489                                                      
REMARK 465     ALA A   490                                                      
REMARK 465     LEU A   491                                                      
REMARK 465     LYS A   492                                                      
REMARK 465     GLY A   493                                                      
REMARK 465     GLY A   494                                                      
REMARK 465     ALA A   495                                                      
REMARK 465     ALA A   496                                                      
REMARK 465     GLU A   497                                                      
REMARK 465     LEU A   498                                                      
REMARK 465     ARG A   499                                                      
REMARK 465     PRO A   500                                                      
REMARK 465     PRO A   501                                                      
REMARK 465     ASP A   502                                                      
REMARK 465     VAL A   503                                                      
REMARK 465     GLY A   504                                                      
REMARK 465     HIS A   505                                                      
REMARK 465     VAL A   506                                                      
REMARK 465     LEU A   507                                                      
REMARK 465     ARG A   508                                                      
REMARK 465     MET A   509                                                      
REMARK 465     LEU A   510                                                      
REMARK 465     LEU A   511                                                      
REMARK 465     GLY A   512                                                      
REMARK 465     LYS A   513                                                      
REMARK 465     MET A   514                                                      
REMARK 465     CYS A   515                                                      
REMARK 465     ALA A   516                                                      
REMARK 465     PRO A   517                                                      
REMARK 465     ARG A   518                                                      
REMARK 465     TYR A   519                                                      
REMARK 465     PRO A   520                                                      
REMARK 465     SER A   521                                                      
REMARK 465     GLY A   522                                                      
REMARK 465     GLY A   523                                                      
REMARK 465     ALA A   524                                                      
REMARK 465     TRP A   525                                                      
REMARK 465     ASP A   526                                                      
REMARK 465     PRO A   527                                                      
REMARK 465     HIS A   528                                                      
REMARK 465     PRO A   529                                                      
REMARK 465     GLY A   530                                                      
REMARK 465     GLN A   531                                                      
REMARK 465     GLY A   532                                                      
REMARK 465     PHE A   533                                                      
REMARK 465     GLY A   534                                                      
REMARK 465     GLU A   535                                                      
REMARK 465     SER A   536                                                      
REMARK 465     MET A   537                                                      
REMARK 465     TYR A   538                                                      
REMARK 465     LEU A   539                                                      
REMARK 465     LEU A   540                                                      
REMARK 465     SER A   541                                                      
REMARK 465     ASP A   542                                                      
REMARK 465     LYS A   543                                                      
REMARK 465     ALA A   544                                                      
REMARK 465     THR A   545                                                      
REMARK 465     SER A   546                                                      
REMARK 465     PRO A   547                                                      
REMARK 465     LEU A   548                                                      
REMARK 465     SER A   549                                                      
REMARK 465     LEU A   550                                                      
REMARK 465     ASP A   551                                                      
REMARK 465     ALA A   552                                                      
REMARK 465     GLY A   553                                                      
REMARK 465     LEU A   554                                                      
REMARK 465     GLY A   555                                                      
REMARK 465     GLN A   556                                                      
REMARK 465     ALA A   557                                                      
REMARK 465     ARG A   711                                                      
REMARK 465     LYS A   712                                                      
REMARK 465     SER A   713                                                      
REMARK 465     GLU A   714                                                      
REMARK 465     GLU A   715                                                      
REMARK 465     GLU A   716                                                      
REMARK 465     PRO A   717                                                      
REMARK 465     THR A   718                                                      
REMARK 465     ARG A   719                                                      
REMARK 465     GLU A   720                                                      
REMARK 465     GLU A   721                                                      
REMARK 465     LEU A   722                                                      
REMARK 465     GLU A   723                                                      
REMARK 465     PHE A   724                                                      
REMARK 465     ASP A   725                                                      
REMARK 465     MET A   726                                                      
REMARK 465     ASP A   727                                                      
REMARK 465     SER A   728                                                      
REMARK 465     VAL A   729                                                      
REMARK 465     ILE A   730                                                      
REMARK 465     ASN A   731                                                      
REMARK 465     GLY A   732                                                      
REMARK 465     GLU A   733                                                      
REMARK 465     GLY A   734                                                      
REMARK 465     PRO A   735                                                      
REMARK 465     VAL A   736                                                      
REMARK 465     GLY A   737                                                      
REMARK 465     THR A   738                                                      
REMARK 465     ALA A   739                                                      
REMARK 465     ASP A   740                                                      
REMARK 465     PRO A   741                                                      
REMARK 465     ALA A   742                                                      
REMARK 465     GLU A   743                                                      
REMARK 465     LYS A   744                                                      
REMARK 465     THR A   745                                                      
REMARK 465     PRO A   746                                                      
REMARK 465     LEU A   747                                                      
REMARK 465     GLY A   748                                                      
REMARK 465     VAL A   749                                                      
REMARK 465     PRO A   750                                                      
REMARK 465     ARG A   751                                                      
REMARK 465     GLN A   752                                                      
REMARK 465     SER A   753                                                      
REMARK 465     GLY A   754                                                      
REMARK 465     ARG A   755                                                      
REMARK 465     PRO A   756                                                      
REMARK 465     GLY A   757                                                      
REMARK 465     CYS A   758                                                      
REMARK 465     CYS A   759                                                      
REMARK 465     GLY A   760                                                      
REMARK 465     GLY A   761                                                      
REMARK 465     ARG A   762                                                      
REMARK 465     CYS A   763                                                      
REMARK 465     GLY A   764                                                      
REMARK 465     GLY A   765                                                      
REMARK 465     GLY A   836                                                      
REMARK 465     GLY A   837                                                      
REMARK 465     LEU A  1092                                                      
REMARK 465     CYS A  1093                                                      
REMARK 465     ARG A  1094                                                      
REMARK 465     ARG A  1095                                                      
REMARK 465     PRO A  1096                                                      
REMARK 465     ARG A  1097                                                      
REMARK 465     SER A  1098                                                      
REMARK 465     PRO A  1099                                                      
REMARK 465     GLN A  1100                                                      
REMARK 465     PRO A  1101                                                      
REMARK 465     SER A  1102                                                      
REMARK 465     SER A  1103                                                      
REMARK 465     PRO A  1104                                                      
REMARK 465     SER A  1194                                                      
REMARK 465     ARG A  1195                                                      
REMARK 465     SER A  1196                                                      
REMARK 465     ALA A  1197                                                      
REMARK 465     LEU A  1198                                                      
REMARK 465     LEU A  1199                                                      
REMARK 465     PRO A  1200                                                      
REMARK 465     PRO A  1201                                                      
REMARK 465     GLY A  1202                                                      
REMARK 465     GLY A  1203                                                      
REMARK 465     PRO A  1204                                                      
REMARK 465     PRO A  1205                                                      
REMARK 465     PRO A  1206                                                      
REMARK 465     PRO A  1207                                                      
REMARK 465     ASP A  1208                                                      
REMARK 465     LEU A  1209                                                      
REMARK 465     PRO A  1210                                                      
REMARK 465     GLY A  1211                                                      
REMARK 465     SER A  1212                                                      
REMARK 465     LYS A  1213                                                      
REMARK 465     ASP A  1214                                                      
REMARK 465     MET B     1                                                      
REMARK 465     VAL B     2                                                      
REMARK 465     VAL B     3                                                      
REMARK 465     PRO B     4                                                      
REMARK 465     GLU B     5                                                      
REMARK 465     LYS B     6                                                      
REMARK 465     THR B    21                                                      
REMARK 465     THR B    22                                                      
REMARK 465     PHE B    23                                                      
REMARK 465     ILE B    24                                                      
REMARK 465     VAL B    25                                                      
REMARK 465     ASP B    26                                                      
REMARK 465     SER B    27                                                      
REMARK 465     THR B    28                                                      
REMARK 465     ASP B    29                                                      
REMARK 465     PRO B    30                                                      
REMARK 465     GLY B    31                                                      
REMARK 465     GLY B    32                                                      
REMARK 465     THR B    33                                                      
REMARK 465     LEU B    34                                                      
REMARK 465     CYS B    35                                                      
REMARK 465     GLN B    36                                                      
REMARK 465     CYS B    37                                                      
REMARK 465     GLY B    38                                                      
REMARK 465     ARG B    39                                                      
REMARK 465     PRO B    40                                                      
REMARK 465     ARG B    41                                                      
REMARK 465     THR B    42                                                      
REMARK 465     ALA B    43                                                      
REMARK 465     HIS B    44                                                      
REMARK 465     PRO B    45                                                      
REMARK 465     ALA B    46                                                      
REMARK 465     VAL B    47                                                      
REMARK 465     ALA B    48                                                      
REMARK 465     MET B    49                                                      
REMARK 465     GLU B    50                                                      
REMARK 465     ASP B    51                                                      
REMARK 465     ALA B    52                                                      
REMARK 465     PHE B    53                                                      
REMARK 465     GLY B    54                                                      
REMARK 465     ALA B    55                                                      
REMARK 465     ALA B    56                                                      
REMARK 465     VAL B    57                                                      
REMARK 465     VAL B    58                                                      
REMARK 465     THR B    59                                                      
REMARK 465     VAL B    60                                                      
REMARK 465     TRP B    61                                                      
REMARK 465     ASP B    62                                                      
REMARK 465     SER B    63                                                      
REMARK 465     ASP B    64                                                      
REMARK 465     ALA B    65                                                      
REMARK 465     ASP B   216                                                      
REMARK 465     PRO B   217                                                      
REMARK 465     GLU B   218                                                      
REMARK 465     ASP B   219                                                      
REMARK 465     GLY B   220                                                      
REMARK 465     LEU B   319                                                      
REMARK 465     ALA B   320                                                      
REMARK 465     PRO B   321                                                      
REMARK 465     GLY B   322                                                      
REMARK 465     SER B   323                                                      
REMARK 465     GLY B   324                                                      
REMARK 465     GLY B   325                                                      
REMARK 465     ALA B   326                                                      
REMARK 465     SER B   388                                                      
REMARK 465     GLU B   389                                                      
REMARK 465     ALA B   390                                                      
REMARK 465     SER B   391                                                      
REMARK 465     ALA B   392                                                      
REMARK 465     SER B   481                                                      
REMARK 465     HIS B   482                                                      
REMARK 465     SER B   483                                                      
REMARK 465     ALA B   484                                                      
REMARK 465     GLY B   485                                                      
REMARK 465     THR B   486                                                      
REMARK 465     LYS B   487                                                      
REMARK 465     ALA B   488                                                      
REMARK 465     PRO B   489                                                      
REMARK 465     ALA B   490                                                      
REMARK 465     LEU B   491                                                      
REMARK 465     LYS B   492                                                      
REMARK 465     GLY B   493                                                      
REMARK 465     GLY B   494                                                      
REMARK 465     ALA B   495                                                      
REMARK 465     ALA B   496                                                      
REMARK 465     GLU B   497                                                      
REMARK 465     LEU B   498                                                      
REMARK 465     ARG B   499                                                      
REMARK 465     PRO B   500                                                      
REMARK 465     PRO B   501                                                      
REMARK 465     ASP B   502                                                      
REMARK 465     VAL B   503                                                      
REMARK 465     GLY B   504                                                      
REMARK 465     HIS B   505                                                      
REMARK 465     VAL B   506                                                      
REMARK 465     LEU B   507                                                      
REMARK 465     ARG B   508                                                      
REMARK 465     MET B   509                                                      
REMARK 465     LEU B   510                                                      
REMARK 465     LEU B   511                                                      
REMARK 465     GLY B   512                                                      
REMARK 465     LYS B   513                                                      
REMARK 465     MET B   514                                                      
REMARK 465     CYS B   515                                                      
REMARK 465     ALA B   516                                                      
REMARK 465     PRO B   517                                                      
REMARK 465     ARG B   518                                                      
REMARK 465     TYR B   519                                                      
REMARK 465     PRO B   520                                                      
REMARK 465     SER B   521                                                      
REMARK 465     GLY B   522                                                      
REMARK 465     GLY B   523                                                      
REMARK 465     ALA B   524                                                      
REMARK 465     TRP B   525                                                      
REMARK 465     ASP B   526                                                      
REMARK 465     PRO B   527                                                      
REMARK 465     HIS B   528                                                      
REMARK 465     PRO B   529                                                      
REMARK 465     GLY B   530                                                      
REMARK 465     GLN B   531                                                      
REMARK 465     GLY B   532                                                      
REMARK 465     PHE B   533                                                      
REMARK 465     GLY B   534                                                      
REMARK 465     GLU B   535                                                      
REMARK 465     SER B   536                                                      
REMARK 465     MET B   537                                                      
REMARK 465     TYR B   538                                                      
REMARK 465     LEU B   539                                                      
REMARK 465     LEU B   540                                                      
REMARK 465     SER B   541                                                      
REMARK 465     ASP B   542                                                      
REMARK 465     LYS B   543                                                      
REMARK 465     ALA B   544                                                      
REMARK 465     THR B   545                                                      
REMARK 465     SER B   546                                                      
REMARK 465     PRO B   547                                                      
REMARK 465     LEU B   548                                                      
REMARK 465     SER B   549                                                      
REMARK 465     LEU B   550                                                      
REMARK 465     ASP B   551                                                      
REMARK 465     ALA B   552                                                      
REMARK 465     GLY B   553                                                      
REMARK 465     LEU B   554                                                      
REMARK 465     GLY B   555                                                      
REMARK 465     GLN B   556                                                      
REMARK 465     ALA B   557                                                      
REMARK 465     ARG B   711                                                      
REMARK 465     LYS B   712                                                      
REMARK 465     SER B   713                                                      
REMARK 465     GLU B   714                                                      
REMARK 465     GLU B   715                                                      
REMARK 465     GLU B   716                                                      
REMARK 465     PRO B   717                                                      
REMARK 465     THR B   718                                                      
REMARK 465     ARG B   719                                                      
REMARK 465     GLU B   720                                                      
REMARK 465     GLU B   721                                                      
REMARK 465     LEU B   722                                                      
REMARK 465     GLU B   723                                                      
REMARK 465     PHE B   724                                                      
REMARK 465     ASP B   725                                                      
REMARK 465     MET B   726                                                      
REMARK 465     ASP B   727                                                      
REMARK 465     SER B   728                                                      
REMARK 465     VAL B   729                                                      
REMARK 465     ILE B   730                                                      
REMARK 465     ASN B   731                                                      
REMARK 465     GLY B   732                                                      
REMARK 465     GLU B   733                                                      
REMARK 465     GLY B   734                                                      
REMARK 465     PRO B   735                                                      
REMARK 465     VAL B   736                                                      
REMARK 465     GLY B   737                                                      
REMARK 465     THR B   738                                                      
REMARK 465     ALA B   739                                                      
REMARK 465     ASP B   740                                                      
REMARK 465     PRO B   741                                                      
REMARK 465     ALA B   742                                                      
REMARK 465     GLU B   743                                                      
REMARK 465     LYS B   744                                                      
REMARK 465     THR B   745                                                      
REMARK 465     PRO B   746                                                      
REMARK 465     LEU B   747                                                      
REMARK 465     GLY B   748                                                      
REMARK 465     VAL B   749                                                      
REMARK 465     PRO B   750                                                      
REMARK 465     ARG B   751                                                      
REMARK 465     GLN B   752                                                      
REMARK 465     SER B   753                                                      
REMARK 465     GLY B   754                                                      
REMARK 465     ARG B   755                                                      
REMARK 465     PRO B   756                                                      
REMARK 465     GLY B   757                                                      
REMARK 465     CYS B   758                                                      
REMARK 465     CYS B   759                                                      
REMARK 465     GLY B   760                                                      
REMARK 465     GLY B   761                                                      
REMARK 465     ARG B   762                                                      
REMARK 465     CYS B   763                                                      
REMARK 465     GLY B   764                                                      
REMARK 465     GLY B   765                                                      
REMARK 465     GLY B   836                                                      
REMARK 465     GLY B   837                                                      
REMARK 465     LEU B  1092                                                      
REMARK 465     CYS B  1093                                                      
REMARK 465     ARG B  1094                                                      
REMARK 465     ARG B  1095                                                      
REMARK 465     PRO B  1096                                                      
REMARK 465     ARG B  1097                                                      
REMARK 465     SER B  1098                                                      
REMARK 465     PRO B  1099                                                      
REMARK 465     GLN B  1100                                                      
REMARK 465     PRO B  1101                                                      
REMARK 465     SER B  1102                                                      
REMARK 465     SER B  1103                                                      
REMARK 465     PRO B  1104                                                      
REMARK 465     SER B  1194                                                      
REMARK 465     ARG B  1195                                                      
REMARK 465     SER B  1196                                                      
REMARK 465     ALA B  1197                                                      
REMARK 465     LEU B  1198                                                      
REMARK 465     LEU B  1199                                                      
REMARK 465     PRO B  1200                                                      
REMARK 465     PRO B  1201                                                      
REMARK 465     GLY B  1202                                                      
REMARK 465     GLY B  1203                                                      
REMARK 465     PRO B  1204                                                      
REMARK 465     PRO B  1205                                                      
REMARK 465     PRO B  1206                                                      
REMARK 465     PRO B  1207                                                      
REMARK 465     ASP B  1208                                                      
REMARK 465     LEU B  1209                                                      
REMARK 465     PRO B  1210                                                      
REMARK 465     GLY B  1211                                                      
REMARK 465     SER B  1212                                                      
REMARK 465     LYS B  1213                                                      
REMARK 465     ASP B  1214                                                      
REMARK 465     MET C     1                                                      
REMARK 465     VAL C     2                                                      
REMARK 465     VAL C     3                                                      
REMARK 465     PRO C     4                                                      
REMARK 465     GLU C     5                                                      
REMARK 465     LYS C     6                                                      
REMARK 465     THR C    21                                                      
REMARK 465     THR C    22                                                      
REMARK 465     PHE C    23                                                      
REMARK 465     ILE C    24                                                      
REMARK 465     VAL C    25                                                      
REMARK 465     ASP C    26                                                      
REMARK 465     SER C    27                                                      
REMARK 465     THR C    28                                                      
REMARK 465     ASP C    29                                                      
REMARK 465     PRO C    30                                                      
REMARK 465     GLY C    31                                                      
REMARK 465     GLY C    32                                                      
REMARK 465     THR C    33                                                      
REMARK 465     LEU C    34                                                      
REMARK 465     CYS C    35                                                      
REMARK 465     GLN C    36                                                      
REMARK 465     CYS C    37                                                      
REMARK 465     GLY C    38                                                      
REMARK 465     ARG C    39                                                      
REMARK 465     PRO C    40                                                      
REMARK 465     ARG C    41                                                      
REMARK 465     THR C    42                                                      
REMARK 465     ALA C    43                                                      
REMARK 465     HIS C    44                                                      
REMARK 465     PRO C    45                                                      
REMARK 465     ALA C    46                                                      
REMARK 465     VAL C    47                                                      
REMARK 465     ALA C    48                                                      
REMARK 465     MET C    49                                                      
REMARK 465     GLU C    50                                                      
REMARK 465     ASP C    51                                                      
REMARK 465     ALA C    52                                                      
REMARK 465     PHE C    53                                                      
REMARK 465     GLY C    54                                                      
REMARK 465     ALA C    55                                                      
REMARK 465     ALA C    56                                                      
REMARK 465     VAL C    57                                                      
REMARK 465     VAL C    58                                                      
REMARK 465     THR C    59                                                      
REMARK 465     VAL C    60                                                      
REMARK 465     TRP C    61                                                      
REMARK 465     ASP C    62                                                      
REMARK 465     SER C    63                                                      
REMARK 465     ASP C    64                                                      
REMARK 465     ALA C    65                                                      
REMARK 465     ASP C   216                                                      
REMARK 465     PRO C   217                                                      
REMARK 465     GLU C   218                                                      
REMARK 465     ASP C   219                                                      
REMARK 465     GLY C   220                                                      
REMARK 465     LEU C   319                                                      
REMARK 465     ALA C   320                                                      
REMARK 465     PRO C   321                                                      
REMARK 465     GLY C   322                                                      
REMARK 465     SER C   323                                                      
REMARK 465     GLY C   324                                                      
REMARK 465     GLY C   325                                                      
REMARK 465     ALA C   326                                                      
REMARK 465     SER C   388                                                      
REMARK 465     GLU C   389                                                      
REMARK 465     ALA C   390                                                      
REMARK 465     SER C   391                                                      
REMARK 465     ALA C   392                                                      
REMARK 465     SER C   481                                                      
REMARK 465     HIS C   482                                                      
REMARK 465     SER C   483                                                      
REMARK 465     ALA C   484                                                      
REMARK 465     GLY C   485                                                      
REMARK 465     THR C   486                                                      
REMARK 465     LYS C   487                                                      
REMARK 465     ALA C   488                                                      
REMARK 465     PRO C   489                                                      
REMARK 465     ALA C   490                                                      
REMARK 465     LEU C   491                                                      
REMARK 465     LYS C   492                                                      
REMARK 465     GLY C   493                                                      
REMARK 465     GLY C   494                                                      
REMARK 465     ALA C   495                                                      
REMARK 465     ALA C   496                                                      
REMARK 465     GLU C   497                                                      
REMARK 465     LEU C   498                                                      
REMARK 465     ARG C   499                                                      
REMARK 465     PRO C   500                                                      
REMARK 465     PRO C   501                                                      
REMARK 465     ASP C   502                                                      
REMARK 465     VAL C   503                                                      
REMARK 465     GLY C   504                                                      
REMARK 465     HIS C   505                                                      
REMARK 465     VAL C   506                                                      
REMARK 465     LEU C   507                                                      
REMARK 465     ARG C   508                                                      
REMARK 465     MET C   509                                                      
REMARK 465     LEU C   510                                                      
REMARK 465     LEU C   511                                                      
REMARK 465     GLY C   512                                                      
REMARK 465     LYS C   513                                                      
REMARK 465     MET C   514                                                      
REMARK 465     CYS C   515                                                      
REMARK 465     ALA C   516                                                      
REMARK 465     PRO C   517                                                      
REMARK 465     ARG C   518                                                      
REMARK 465     TYR C   519                                                      
REMARK 465     PRO C   520                                                      
REMARK 465     SER C   521                                                      
REMARK 465     GLY C   522                                                      
REMARK 465     GLY C   523                                                      
REMARK 465     ALA C   524                                                      
REMARK 465     TRP C   525                                                      
REMARK 465     ASP C   526                                                      
REMARK 465     PRO C   527                                                      
REMARK 465     HIS C   528                                                      
REMARK 465     PRO C   529                                                      
REMARK 465     GLY C   530                                                      
REMARK 465     GLN C   531                                                      
REMARK 465     GLY C   532                                                      
REMARK 465     PHE C   533                                                      
REMARK 465     GLY C   534                                                      
REMARK 465     GLU C   535                                                      
REMARK 465     SER C   536                                                      
REMARK 465     MET C   537                                                      
REMARK 465     TYR C   538                                                      
REMARK 465     LEU C   539                                                      
REMARK 465     LEU C   540                                                      
REMARK 465     SER C   541                                                      
REMARK 465     ASP C   542                                                      
REMARK 465     LYS C   543                                                      
REMARK 465     ALA C   544                                                      
REMARK 465     THR C   545                                                      
REMARK 465     SER C   546                                                      
REMARK 465     PRO C   547                                                      
REMARK 465     LEU C   548                                                      
REMARK 465     SER C   549                                                      
REMARK 465     LEU C   550                                                      
REMARK 465     ASP C   551                                                      
REMARK 465     ALA C   552                                                      
REMARK 465     GLY C   553                                                      
REMARK 465     LEU C   554                                                      
REMARK 465     GLY C   555                                                      
REMARK 465     GLN C   556                                                      
REMARK 465     ALA C   557                                                      
REMARK 465     ARG C   711                                                      
REMARK 465     LYS C   712                                                      
REMARK 465     SER C   713                                                      
REMARK 465     GLU C   714                                                      
REMARK 465     GLU C   715                                                      
REMARK 465     GLU C   716                                                      
REMARK 465     PRO C   717                                                      
REMARK 465     THR C   718                                                      
REMARK 465     ARG C   719                                                      
REMARK 465     GLU C   720                                                      
REMARK 465     GLU C   721                                                      
REMARK 465     LEU C   722                                                      
REMARK 465     GLU C   723                                                      
REMARK 465     PHE C   724                                                      
REMARK 465     ASP C   725                                                      
REMARK 465     MET C   726                                                      
REMARK 465     ASP C   727                                                      
REMARK 465     SER C   728                                                      
REMARK 465     VAL C   729                                                      
REMARK 465     ILE C   730                                                      
REMARK 465     ASN C   731                                                      
REMARK 465     GLY C   732                                                      
REMARK 465     GLU C   733                                                      
REMARK 465     GLY C   734                                                      
REMARK 465     PRO C   735                                                      
REMARK 465     VAL C   736                                                      
REMARK 465     GLY C   737                                                      
REMARK 465     THR C   738                                                      
REMARK 465     ALA C   739                                                      
REMARK 465     ASP C   740                                                      
REMARK 465     PRO C   741                                                      
REMARK 465     ALA C   742                                                      
REMARK 465     GLU C   743                                                      
REMARK 465     LYS C   744                                                      
REMARK 465     THR C   745                                                      
REMARK 465     PRO C   746                                                      
REMARK 465     LEU C   747                                                      
REMARK 465     GLY C   748                                                      
REMARK 465     VAL C   749                                                      
REMARK 465     PRO C   750                                                      
REMARK 465     ARG C   751                                                      
REMARK 465     GLN C   752                                                      
REMARK 465     SER C   753                                                      
REMARK 465     GLY C   754                                                      
REMARK 465     ARG C   755                                                      
REMARK 465     PRO C   756                                                      
REMARK 465     GLY C   757                                                      
REMARK 465     CYS C   758                                                      
REMARK 465     CYS C   759                                                      
REMARK 465     GLY C   760                                                      
REMARK 465     GLY C   761                                                      
REMARK 465     ARG C   762                                                      
REMARK 465     CYS C   763                                                      
REMARK 465     GLY C   764                                                      
REMARK 465     GLY C   765                                                      
REMARK 465     GLY C   836                                                      
REMARK 465     GLY C   837                                                      
REMARK 465     LEU C  1092                                                      
REMARK 465     CYS C  1093                                                      
REMARK 465     ARG C  1094                                                      
REMARK 465     ARG C  1095                                                      
REMARK 465     PRO C  1096                                                      
REMARK 465     ARG C  1097                                                      
REMARK 465     SER C  1098                                                      
REMARK 465     PRO C  1099                                                      
REMARK 465     GLN C  1100                                                      
REMARK 465     PRO C  1101                                                      
REMARK 465     SER C  1102                                                      
REMARK 465     SER C  1103                                                      
REMARK 465     PRO C  1104                                                      
REMARK 465     SER C  1194                                                      
REMARK 465     ARG C  1195                                                      
REMARK 465     SER C  1196                                                      
REMARK 465     ALA C  1197                                                      
REMARK 465     LEU C  1198                                                      
REMARK 465     LEU C  1199                                                      
REMARK 465     PRO C  1200                                                      
REMARK 465     PRO C  1201                                                      
REMARK 465     GLY C  1202                                                      
REMARK 465     GLY C  1203                                                      
REMARK 465     PRO C  1204                                                      
REMARK 465     PRO C  1205                                                      
REMARK 465     PRO C  1206                                                      
REMARK 465     PRO C  1207                                                      
REMARK 465     ASP C  1208                                                      
REMARK 465     LEU C  1209                                                      
REMARK 465     PRO C  1210                                                      
REMARK 465     GLY C  1211                                                      
REMARK 465     SER C  1212                                                      
REMARK 465     LYS C  1213                                                      
REMARK 465     ASP C  1214                                                      
REMARK 465     MET D     1                                                      
REMARK 465     VAL D     2                                                      
REMARK 465     VAL D     3                                                      
REMARK 465     PRO D     4                                                      
REMARK 465     GLU D     5                                                      
REMARK 465     LYS D     6                                                      
REMARK 465     THR D    21                                                      
REMARK 465     THR D    22                                                      
REMARK 465     PHE D    23                                                      
REMARK 465     ILE D    24                                                      
REMARK 465     VAL D    25                                                      
REMARK 465     ASP D    26                                                      
REMARK 465     SER D    27                                                      
REMARK 465     THR D    28                                                      
REMARK 465     ASP D    29                                                      
REMARK 465     PRO D    30                                                      
REMARK 465     GLY D    31                                                      
REMARK 465     GLY D    32                                                      
REMARK 465     THR D    33                                                      
REMARK 465     LEU D    34                                                      
REMARK 465     CYS D    35                                                      
REMARK 465     GLN D    36                                                      
REMARK 465     CYS D    37                                                      
REMARK 465     GLY D    38                                                      
REMARK 465     ARG D    39                                                      
REMARK 465     PRO D    40                                                      
REMARK 465     ARG D    41                                                      
REMARK 465     THR D    42                                                      
REMARK 465     ALA D    43                                                      
REMARK 465     HIS D    44                                                      
REMARK 465     PRO D    45                                                      
REMARK 465     ALA D    46                                                      
REMARK 465     VAL D    47                                                      
REMARK 465     ALA D    48                                                      
REMARK 465     MET D    49                                                      
REMARK 465     GLU D    50                                                      
REMARK 465     ASP D    51                                                      
REMARK 465     ALA D    52                                                      
REMARK 465     PHE D    53                                                      
REMARK 465     GLY D    54                                                      
REMARK 465     ALA D    55                                                      
REMARK 465     ALA D    56                                                      
REMARK 465     VAL D    57                                                      
REMARK 465     VAL D    58                                                      
REMARK 465     THR D    59                                                      
REMARK 465     VAL D    60                                                      
REMARK 465     TRP D    61                                                      
REMARK 465     ASP D    62                                                      
REMARK 465     SER D    63                                                      
REMARK 465     ASP D    64                                                      
REMARK 465     ALA D    65                                                      
REMARK 465     ASP D   216                                                      
REMARK 465     PRO D   217                                                      
REMARK 465     GLU D   218                                                      
REMARK 465     ASP D   219                                                      
REMARK 465     GLY D   220                                                      
REMARK 465     LEU D   319                                                      
REMARK 465     ALA D   320                                                      
REMARK 465     PRO D   321                                                      
REMARK 465     GLY D   322                                                      
REMARK 465     SER D   323                                                      
REMARK 465     GLY D   324                                                      
REMARK 465     GLY D   325                                                      
REMARK 465     ALA D   326                                                      
REMARK 465     SER D   388                                                      
REMARK 465     GLU D   389                                                      
REMARK 465     ALA D   390                                                      
REMARK 465     SER D   391                                                      
REMARK 465     ALA D   392                                                      
REMARK 465     SER D   481                                                      
REMARK 465     HIS D   482                                                      
REMARK 465     SER D   483                                                      
REMARK 465     ALA D   484                                                      
REMARK 465     GLY D   485                                                      
REMARK 465     THR D   486                                                      
REMARK 465     LYS D   487                                                      
REMARK 465     ALA D   488                                                      
REMARK 465     PRO D   489                                                      
REMARK 465     ALA D   490                                                      
REMARK 465     LEU D   491                                                      
REMARK 465     LYS D   492                                                      
REMARK 465     GLY D   493                                                      
REMARK 465     GLY D   494                                                      
REMARK 465     ALA D   495                                                      
REMARK 465     ALA D   496                                                      
REMARK 465     GLU D   497                                                      
REMARK 465     LEU D   498                                                      
REMARK 465     ARG D   499                                                      
REMARK 465     PRO D   500                                                      
REMARK 465     PRO D   501                                                      
REMARK 465     ASP D   502                                                      
REMARK 465     VAL D   503                                                      
REMARK 465     GLY D   504                                                      
REMARK 465     HIS D   505                                                      
REMARK 465     VAL D   506                                                      
REMARK 465     LEU D   507                                                      
REMARK 465     ARG D   508                                                      
REMARK 465     MET D   509                                                      
REMARK 465     LEU D   510                                                      
REMARK 465     LEU D   511                                                      
REMARK 465     GLY D   512                                                      
REMARK 465     LYS D   513                                                      
REMARK 465     MET D   514                                                      
REMARK 465     CYS D   515                                                      
REMARK 465     ALA D   516                                                      
REMARK 465     PRO D   517                                                      
REMARK 465     ARG D   518                                                      
REMARK 465     TYR D   519                                                      
REMARK 465     PRO D   520                                                      
REMARK 465     SER D   521                                                      
REMARK 465     GLY D   522                                                      
REMARK 465     GLY D   523                                                      
REMARK 465     ALA D   524                                                      
REMARK 465     TRP D   525                                                      
REMARK 465     ASP D   526                                                      
REMARK 465     PRO D   527                                                      
REMARK 465     HIS D   528                                                      
REMARK 465     PRO D   529                                                      
REMARK 465     GLY D   530                                                      
REMARK 465     GLN D   531                                                      
REMARK 465     GLY D   532                                                      
REMARK 465     PHE D   533                                                      
REMARK 465     GLY D   534                                                      
REMARK 465     GLU D   535                                                      
REMARK 465     SER D   536                                                      
REMARK 465     MET D   537                                                      
REMARK 465     TYR D   538                                                      
REMARK 465     LEU D   539                                                      
REMARK 465     LEU D   540                                                      
REMARK 465     SER D   541                                                      
REMARK 465     ASP D   542                                                      
REMARK 465     LYS D   543                                                      
REMARK 465     ALA D   544                                                      
REMARK 465     THR D   545                                                      
REMARK 465     SER D   546                                                      
REMARK 465     PRO D   547                                                      
REMARK 465     LEU D   548                                                      
REMARK 465     SER D   549                                                      
REMARK 465     LEU D   550                                                      
REMARK 465     ASP D   551                                                      
REMARK 465     ALA D   552                                                      
REMARK 465     GLY D   553                                                      
REMARK 465     LEU D   554                                                      
REMARK 465     GLY D   555                                                      
REMARK 465     GLN D   556                                                      
REMARK 465     ALA D   557                                                      
REMARK 465     ARG D   711                                                      
REMARK 465     LYS D   712                                                      
REMARK 465     SER D   713                                                      
REMARK 465     GLU D   714                                                      
REMARK 465     GLU D   715                                                      
REMARK 465     GLU D   716                                                      
REMARK 465     PRO D   717                                                      
REMARK 465     THR D   718                                                      
REMARK 465     ARG D   719                                                      
REMARK 465     GLU D   720                                                      
REMARK 465     GLU D   721                                                      
REMARK 465     LEU D   722                                                      
REMARK 465     GLU D   723                                                      
REMARK 465     PHE D   724                                                      
REMARK 465     ASP D   725                                                      
REMARK 465     MET D   726                                                      
REMARK 465     ASP D   727                                                      
REMARK 465     SER D   728                                                      
REMARK 465     VAL D   729                                                      
REMARK 465     ILE D   730                                                      
REMARK 465     ASN D   731                                                      
REMARK 465     GLY D   732                                                      
REMARK 465     GLU D   733                                                      
REMARK 465     GLY D   734                                                      
REMARK 465     PRO D   735                                                      
REMARK 465     VAL D   736                                                      
REMARK 465     GLY D   737                                                      
REMARK 465     THR D   738                                                      
REMARK 465     ALA D   739                                                      
REMARK 465     ASP D   740                                                      
REMARK 465     PRO D   741                                                      
REMARK 465     ALA D   742                                                      
REMARK 465     GLU D   743                                                      
REMARK 465     LYS D   744                                                      
REMARK 465     THR D   745                                                      
REMARK 465     PRO D   746                                                      
REMARK 465     LEU D   747                                                      
REMARK 465     GLY D   748                                                      
REMARK 465     VAL D   749                                                      
REMARK 465     PRO D   750                                                      
REMARK 465     ARG D   751                                                      
REMARK 465     GLN D   752                                                      
REMARK 465     SER D   753                                                      
REMARK 465     GLY D   754                                                      
REMARK 465     ARG D   755                                                      
REMARK 465     PRO D   756                                                      
REMARK 465     GLY D   757                                                      
REMARK 465     CYS D   758                                                      
REMARK 465     CYS D   759                                                      
REMARK 465     GLY D   760                                                      
REMARK 465     GLY D   761                                                      
REMARK 465     ARG D   762                                                      
REMARK 465     CYS D   763                                                      
REMARK 465     GLY D   764                                                      
REMARK 465     GLY D   765                                                      
REMARK 465     GLY D   836                                                      
REMARK 465     GLY D   837                                                      
REMARK 465     LEU D  1092                                                      
REMARK 465     CYS D  1093                                                      
REMARK 465     ARG D  1094                                                      
REMARK 465     ARG D  1095                                                      
REMARK 465     PRO D  1096                                                      
REMARK 465     ARG D  1097                                                      
REMARK 465     SER D  1098                                                      
REMARK 465     PRO D  1099                                                      
REMARK 465     GLN D  1100                                                      
REMARK 465     PRO D  1101                                                      
REMARK 465     SER D  1102                                                      
REMARK 465     SER D  1103                                                      
REMARK 465     PRO D  1104                                                      
REMARK 465     SER D  1194                                                      
REMARK 465     ARG D  1195                                                      
REMARK 465     SER D  1196                                                      
REMARK 465     ALA D  1197                                                      
REMARK 465     LEU D  1198                                                      
REMARK 465     LEU D  1199                                                      
REMARK 465     PRO D  1200                                                      
REMARK 465     PRO D  1201                                                      
REMARK 465     GLY D  1202                                                      
REMARK 465     GLY D  1203                                                      
REMARK 465     PRO D  1204                                                      
REMARK 465     PRO D  1205                                                      
REMARK 465     PRO D  1206                                                      
REMARK 465     PRO D  1207                                                      
REMARK 465     ASP D  1208                                                      
REMARK 465     LEU D  1209                                                      
REMARK 465     PRO D  1210                                                      
REMARK 465     GLY D  1211                                                      
REMARK 465     SER D  1212                                                      
REMARK 465     LYS D  1213                                                      
REMARK 465     ASP D  1214                                                      
REMARK 470                                                                      
REMARK 470 MISSING ATOM                                                         
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;           
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;          
REMARK 470 I=INSERTION CODE):                                                   
REMARK 470   M RES CSSEQI  ATOMS                                                
REMARK 470     GLU A   7    CG   CD   OE1  OE2                                  
REMARK 470     LYS A  13    CG   CD   CE   NZ                                   
REMARK 470     CYS A  20    O    SG                                             
REMARK 470     HIS A  66    CG   ND1  CD2  CE1  NE2                             
REMARK 470     THR A  68    OG1  CG2                                            
REMARK 470     GLU A  69    CG   CD   OE1  OE2                                  
REMARK 470     GLU A  77    CG   CD   OE1  OE2                                  
REMARK 470     ARG A  85    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS A  86    CG   CD   CE   NZ                                   
REMARK 470     ARG A  96    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP A  98    CG   OD1  OD2                                       
REMARK 470     ARG A 108    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG A 113    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     SER A 125    OG                                                  
REMARK 470     ASP A 172    CG   OD1  OD2                                       
REMARK 470     MET A 175    CG   SD   CE                                        
REMARK 470     LYS A 182    CG   CD   CE   NZ                                   
REMARK 470     ASP A 198    CG   OD1  OD2                                       
REMARK 470     ASN A 202    CG   OD1  ND2                                       
REMARK 470     LYS A 204    CG   CD   CE   NZ                                   
REMARK 470     SER A 206    OG                                                  
REMARK 470     ARG A 210    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP A 237    CG   OD1  OD2                                       
REMARK 470     CYS A 242    SG                                                  
REMARK 470     LEU A 243    CG   CD1  CD2                                       
REMARK 470     THR A 267    OG1  CG2                                            
REMARK 470     ASP A 281    CG   OD1  OD2                                       
REMARK 470     GLU A 282    CG   CD   OE1  OE2                                  
REMARK 470     LYS A 283    CG   CD   CE   NZ                                   
REMARK 470     GLU A 289    CG   CD   OE1  OE2                                  
REMARK 470     THR A 292    OG1  CG2                                            
REMARK 470     GLN A 295    CG   CD   OE1  NE2                                  
REMARK 470     CYS A 298    SG                                                  
REMARK 470     GLU A 316    CG   CD   OE1  OE2                                  
REMARK 470     ASP A 317    CG   OD1  OD2                                       
REMARK 470     THR A 318    O    OG1  CG2                                       
REMARK 470     ARG A 327    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG A 334    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ILE A 335    CG1  CG2  CD1                                       
REMARK 470     ARG A 336    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG A 337    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     PHE A 338    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     PHE A 339    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     LYS A 341    CG   CD   CE   NZ                                   
REMARK 470     LEU A 344    CG   CD1  CD2                                       
REMARK 470     GLU A 345    CG   CD   OE1  OE2                                  
REMARK 470     GLN A 348    CG   CD   OE1  NE2                                  
REMARK 470     GLN A 350    CG   CD   OE1  NE2                                  
REMARK 470     GLU A 352    CG   CD   OE1  OE2                                  
REMARK 470     LYS A 358    CG   CD   CE   NZ                                   
REMARK 470     GLU A 359    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 367    CG   CD   OE1  OE2                                  
REMARK 470     ASP A 368    CG   OD1  OD2                                       
REMARK 470     SER A 370    OG                                                  
REMARK 470     GLU A 371    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 372    CG   CD   OE1  OE2                                  
REMARK 470     CYS A 385    SG                                                  
REMARK 470     SER A 387    O    OG                                             
REMARK 470     TYR A 393    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     GLU A 412    CG   CD   OE1  OE2                                  
REMARK 470     LEU A 413    CG   CD1  CD2                                       
REMARK 470     PHE A 414    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ARG A 415    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP A 417    CG   OD1  OD2                                       
REMARK 470     ILE A 418    CG1  CG2  CD1                                       
REMARK 470     GLN A 419    CG   CD   OE1  NE2                                  
REMARK 470     GLU A 426    CG   CD   OE1  OE2                                  
REMARK 470     ASP A 436    CG   OD1  OD2                                       
REMARK 470     GLU A 439    CG   CD   OE1  OE2                                  
REMARK 470     SER A 450    OG                                                  
REMARK 470     MET A 458    CG   SD   CE                                        
REMARK 470     GLN A 462    CG   CD   OE1  NE2                                  
REMARK 470     SER A 469    OG                                                  
REMARK 470     ASN A 470    CG   OD1  ND2                                       
REMARK 470     SER A 471    OG                                                  
REMARK 470     ASP A 478    CG   OD1  OD2                                       
REMARK 470     GLN A 479    CG   CD   OE1  NE2                                  
REMARK 470     ASP A 561    CG   OD1  OD2                                       
REMARK 470     GLU A 580    CG   CD   OE1  OE2                                  
REMARK 470     SER A 583    OG                                                  
REMARK 470     MET A 599    CG   SD   CE                                        
REMARK 470     GLU A 603    CG   CD   OE1  OE2                                  
REMARK 470     ASP A 605    CG   OD1  OD2                                       
REMARK 470     GLU A 607    CG   CD   OE1  OE2                                  
REMARK 470     ARG A 611    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU A 629    CG   CD   OE1  OE2                                  
REMARK 470     SER A 634    OG                                                  
REMARK 470     LEU A 648    CG   CD1  CD2                                       
REMARK 470     ASP A 651    CG   OD1  OD2                                       
REMARK 470     ASP A 662    CG   OD1  OD2                                       
REMARK 470     ASP A 683    CG   OD1  OD2                                       
REMARK 470     MET A 684    CG   SD   CE                                        
REMARK 470     SER A 686    OG                                                  
REMARK 470     LEU A 695    CG   CD1  CD2                                       
REMARK 470     PHE A 698    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     THR A 705    OG1  CG2                                            
REMARK 470     ARG A 706    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU A 707    CG   CD1  CD2                                       
REMARK 470     ILE A 708    CG1  CG2  CD1                                       
REMARK 470     THR A 709    OG1  CG2                                            
REMARK 470     ARG A 766    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG A 767    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     CYS A 768    SG                                                  
REMARK 470     ARG A 770    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     PHE A 773    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLN A 806    CG   CD   OE1  NE2                                  
REMARK 470     CYS A 826    SG                                                  
REMARK 470     GLU A 827    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 828    CG   CD   OE1  OE2                                  
REMARK 470     SER A 842    OG                                                  
REMARK 470     HIS A 849    CG   ND1  CD2  CE1  NE2                             
REMARK 470     SER A 851    OG                                                  
REMARK 470     ASP A 868    CG   OD1  OD2                                       
REMARK 470     LEU A 883    CG   CD1  CD2                                       
REMARK 470     ASP A 956    CG   OD1  OD2                                       
REMARK 470     SER A 957    OG                                                  
REMARK 470     GLU A 989    CG   CD   OE1  OE2                                  
REMARK 470     ASN A 992    CG   OD1  ND2                                       
REMARK 470     CYS A 993    SG                                                  
REMARK 470     SER A 995    OG                                                  
REMARK 470     GLU A 996    CG   CD   OE1  OE2                                  
REMARK 470     ARG A1072    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU A1075    CG   CD1  CD2                                       
REMARK 470     PHE A1079    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ILE A1080    CG1  CG2  CD1                                       
REMARK 470     VAL A1081    CG1  CG2                                            
REMARK 470     ILE A1082    CG1  CG2  CD1                                       
REMARK 470     SER A1083    OG                                                  
REMARK 470     HIS A1084    CG   ND1  CD2  CE1  NE2                             
REMARK 470     LEU A1085    CG   CD1  CD2                                       
REMARK 470     ARG A1086    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU A1087    CG   CD1  CD2                                       
REMARK 470     LEU A1088    CG   CD1  CD2                                       
REMARK 470     LEU A1089    CG   CD1  CD2                                       
REMARK 470     ARG A1090    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLN A1091    O    CG   CD   OE1  NE2                             
REMARK 470     GLU A1107    CG   CD   OE1  OE2                                  
REMARK 470     HIS A1108    CG   ND1  CD2  CE1  NE2                             
REMARK 470     PHE A1109    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ARG A1110    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU A1116    CG   CD   OE1  OE2                                  
REMARK 470     GLU A1130    CG   CD   OE1  OE2                                  
REMARK 470     GLU A1142    CG   CD   OE1  OE2                                  
REMARK 470     ASP A1156    CG   OD1  OD2                                       
REMARK 470     GLN A1170    CG   CD   OE1  NE2                                  
REMARK 470     ARG A1171    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS A1173    CG   CD   CE   NZ                                   
REMARK 470     VAL A1174    CG1  CG2                                            
REMARK 470     LEU A1175    CG   CD1  CD2                                       
REMARK 470     GLU A1176    CG   CD   OE1  OE2                                  
REMARK 470     ARG A1177    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU A1178    CG   CD   OE1  OE2                                  
REMARK 470     VAL A1179    CG1  CG2                                            
REMARK 470     GLN A1180    CG   CD   OE1  NE2                                  
REMARK 470     GLN A1181    CG   CD   OE1  NE2                                  
REMARK 470     CYS A1182    SG                                                  
REMARK 470     SER A1183    OG                                                  
REMARK 470     ARG A1184    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     VAL A1185    CG1  CG2                                            
REMARK 470     LEU A1186    CG   CD1  CD2                                       
REMARK 470     TRP A1188    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP A1188    CZ3  CH2                                            
REMARK 470     VAL A1189    CG1  CG2                                            
REMARK 470     GLU A1191    CG   CD   OE1  OE2                                  
REMARK 470     LEU A1193    O    CG   CD1  CD2                                  
REMARK 470     GLU B   7    CG   CD   OE1  OE2                                  
REMARK 470     LYS B  13    CG   CD   CE   NZ                                   
REMARK 470     CYS B  20    O    SG                                             
REMARK 470     HIS B  66    CG   ND1  CD2  CE1  NE2                             
REMARK 470     THR B  68    OG1  CG2                                            
REMARK 470     GLU B  69    CG   CD   OE1  OE2                                  
REMARK 470     GLU B  77    CG   CD   OE1  OE2                                  
REMARK 470     ARG B  85    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS B  86    CG   CD   CE   NZ                                   
REMARK 470     ARG B  96    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP B  98    CG   OD1  OD2                                       
REMARK 470     ARG B 108    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG B 113    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     SER B 125    OG                                                  
REMARK 470     ASP B 172    CG   OD1  OD2                                       
REMARK 470     MET B 175    CG   SD   CE                                        
REMARK 470     LYS B 182    CG   CD   CE   NZ                                   
REMARK 470     ASP B 198    CG   OD1  OD2                                       
REMARK 470     ASN B 202    CG   OD1  ND2                                       
REMARK 470     LYS B 204    CG   CD   CE   NZ                                   
REMARK 470     SER B 206    OG                                                  
REMARK 470     ARG B 210    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP B 237    CG   OD1  OD2                                       
REMARK 470     CYS B 242    SG                                                  
REMARK 470     LEU B 243    CG   CD1  CD2                                       
REMARK 470     THR B 267    OG1  CG2                                            
REMARK 470     ASP B 281    CG   OD1  OD2                                       
REMARK 470     GLU B 282    CG   CD   OE1  OE2                                  
REMARK 470     LYS B 283    CG   CD   CE   NZ                                   
REMARK 470     GLU B 289    CG   CD   OE1  OE2                                  
REMARK 470     THR B 292    OG1  CG2                                            
REMARK 470     GLN B 295    CG   CD   OE1  NE2                                  
REMARK 470     CYS B 298    SG                                                  
REMARK 470     GLU B 316    CG   CD   OE1  OE2                                  
REMARK 470     ASP B 317    CG   OD1  OD2                                       
REMARK 470     THR B 318    O    OG1  CG2                                       
REMARK 470     ARG B 327    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG B 334    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ILE B 335    CG1  CG2  CD1                                       
REMARK 470     ARG B 336    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG B 337    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     PHE B 338    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     PHE B 339    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     LYS B 341    CG   CD   CE   NZ                                   
REMARK 470     LEU B 344    CG   CD1  CD2                                       
REMARK 470     GLU B 345    CG   CD   OE1  OE2                                  
REMARK 470     GLN B 348    CG   CD   OE1  NE2                                  
REMARK 470     GLN B 350    CG   CD   OE1  NE2                                  
REMARK 470     GLU B 352    CG   CD   OE1  OE2                                  
REMARK 470     LYS B 358    CG   CD   CE   NZ                                   
REMARK 470     GLU B 359    CG   CD   OE1  OE2                                  
REMARK 470     GLU B 367    CG   CD   OE1  OE2                                  
REMARK 470     ASP B 368    CG   OD1  OD2                                       
REMARK 470     SER B 370    OG                                                  
REMARK 470     GLU B 371    CG   CD   OE1  OE2                                  
REMARK 470     GLU B 372    CG   CD   OE1  OE2                                  
REMARK 470     CYS B 385    SG                                                  
REMARK 470     SER B 387    O    OG                                             
REMARK 470     TYR B 393    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     GLU B 412    CG   CD   OE1  OE2                                  
REMARK 470     LEU B 413    CG   CD1  CD2                                       
REMARK 470     PHE B 414    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ARG B 415    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP B 417    CG   OD1  OD2                                       
REMARK 470     ILE B 418    CG1  CG2  CD1                                       
REMARK 470     GLN B 419    CG   CD   OE1  NE2                                  
REMARK 470     GLU B 426    CG   CD   OE1  OE2                                  
REMARK 470     ASP B 436    CG   OD1  OD2                                       
REMARK 470     GLU B 439    CG   CD   OE1  OE2                                  
REMARK 470     SER B 450    OG                                                  
REMARK 470     MET B 458    CG   SD   CE                                        
REMARK 470     GLN B 462    CG   CD   OE1  NE2                                  
REMARK 470     SER B 469    OG                                                  
REMARK 470     ASN B 470    CG   OD1  ND2                                       
REMARK 470     SER B 471    OG                                                  
REMARK 470     ASP B 478    CG   OD1  OD2                                       
REMARK 470     GLN B 479    CG   CD   OE1  NE2                                  
REMARK 470     ASP B 561    CG   OD1  OD2                                       
REMARK 470     GLU B 580    CG   CD   OE1  OE2                                  
REMARK 470     SER B 583    OG                                                  
REMARK 470     MET B 599    CG   SD   CE                                        
REMARK 470     GLU B 603    CG   CD   OE1  OE2                                  
REMARK 470     ASP B 605    CG   OD1  OD2                                       
REMARK 470     GLU B 607    CG   CD   OE1  OE2                                  
REMARK 470     ARG B 611    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU B 629    CG   CD   OE1  OE2                                  
REMARK 470     SER B 634    OG                                                  
REMARK 470     LEU B 648    CG   CD1  CD2                                       
REMARK 470     ASP B 651    CG   OD1  OD2                                       
REMARK 470     ASP B 662    CG   OD1  OD2                                       
REMARK 470     ASP B 683    CG   OD1  OD2                                       
REMARK 470     MET B 684    CG   SD   CE                                        
REMARK 470     SER B 686    OG                                                  
REMARK 470     LEU B 695    CG   CD1  CD2                                       
REMARK 470     PHE B 698    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     THR B 705    OG1  CG2                                            
REMARK 470     ARG B 706    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU B 707    CG   CD1  CD2                                       
REMARK 470     ILE B 708    CG1  CG2  CD1                                       
REMARK 470     THR B 709    OG1  CG2                                            
REMARK 470     ARG B 766    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG B 767    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     CYS B 768    SG                                                  
REMARK 470     ARG B 770    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     PHE B 773    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLN B 806    CG   CD   OE1  NE2                                  
REMARK 470     CYS B 826    SG                                                  
REMARK 470     GLU B 827    CG   CD   OE1  OE2                                  
REMARK 470     GLU B 828    CG   CD   OE1  OE2                                  
REMARK 470     SER B 842    OG                                                  
REMARK 470     HIS B 849    CG   ND1  CD2  CE1  NE2                             
REMARK 470     SER B 851    OG                                                  
REMARK 470     ASP B 868    CG   OD1  OD2                                       
REMARK 470     LEU B 883    CG   CD1  CD2                                       
REMARK 470     ASP B 956    CG   OD1  OD2                                       
REMARK 470     SER B 957    OG                                                  
REMARK 470     GLU B 989    CG   CD   OE1  OE2                                  
REMARK 470     ASN B 992    CG   OD1  ND2                                       
REMARK 470     CYS B 993    SG                                                  
REMARK 470     SER B 995    OG                                                  
REMARK 470     GLU B 996    CG   CD   OE1  OE2                                  
REMARK 470     ARG B1072    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU B1075    CG   CD1  CD2                                       
REMARK 470     PHE B1079    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ILE B1080    CG1  CG2  CD1                                       
REMARK 470     VAL B1081    CG1  CG2                                            
REMARK 470     ILE B1082    CG1  CG2  CD1                                       
REMARK 470     SER B1083    OG                                                  
REMARK 470     HIS B1084    CG   ND1  CD2  CE1  NE2                             
REMARK 470     LEU B1085    CG   CD1  CD2                                       
REMARK 470     ARG B1086    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU B1087    CG   CD1  CD2                                       
REMARK 470     LEU B1088    CG   CD1  CD2                                       
REMARK 470     LEU B1089    CG   CD1  CD2                                       
REMARK 470     ARG B1090    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLN B1091    O    CG   CD   OE1  NE2                             
REMARK 470     GLU B1107    CG   CD   OE1  OE2                                  
REMARK 470     HIS B1108    CG   ND1  CD2  CE1  NE2                             
REMARK 470     PHE B1109    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ARG B1110    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU B1116    CG   CD   OE1  OE2                                  
REMARK 470     GLU B1130    CG   CD   OE1  OE2                                  
REMARK 470     GLU B1142    CG   CD   OE1  OE2                                  
REMARK 470     ASP B1156    CG   OD1  OD2                                       
REMARK 470     GLN B1170    CG   CD   OE1  NE2                                  
REMARK 470     ARG B1171    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS B1173    CG   CD   CE   NZ                                   
REMARK 470     VAL B1174    CG1  CG2                                            
REMARK 470     LEU B1175    CG   CD1  CD2                                       
REMARK 470     GLU B1176    CG   CD   OE1  OE2                                  
REMARK 470     ARG B1177    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU B1178    CG   CD   OE1  OE2                                  
REMARK 470     VAL B1179    CG1  CG2                                            
REMARK 470     GLN B1180    CG   CD   OE1  NE2                                  
REMARK 470     GLN B1181    CG   CD   OE1  NE2                                  
REMARK 470     CYS B1182    SG                                                  
REMARK 470     SER B1183    OG                                                  
REMARK 470     ARG B1184    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     VAL B1185    CG1  CG2                                            
REMARK 470     LEU B1186    CG   CD1  CD2                                       
REMARK 470     TRP B1188    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP B1188    CZ3  CH2                                            
REMARK 470     VAL B1189    CG1  CG2                                            
REMARK 470     GLU B1191    CG   CD   OE1  OE2                                  
REMARK 470     LEU B1193    O    CG   CD1  CD2                                  
REMARK 470     GLU C   7    CG   CD   OE1  OE2                                  
REMARK 470     LYS C  13    CG   CD   CE   NZ                                   
REMARK 470     CYS C  20    O    SG                                             
REMARK 470     HIS C  66    CG   ND1  CD2  CE1  NE2                             
REMARK 470     THR C  68    OG1  CG2                                            
REMARK 470     GLU C  69    CG   CD   OE1  OE2                                  
REMARK 470     GLU C  77    CG   CD   OE1  OE2                                  
REMARK 470     ARG C  85    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS C  86    CG   CD   CE   NZ                                   
REMARK 470     ARG C  96    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP C  98    CG   OD1  OD2                                       
REMARK 470     ARG C 108    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG C 113    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     SER C 125    OG                                                  
REMARK 470     ASP C 172    CG   OD1  OD2                                       
REMARK 470     MET C 175    CG   SD   CE                                        
REMARK 470     LYS C 182    CG   CD   CE   NZ                                   
REMARK 470     ASP C 198    CG   OD1  OD2                                       
REMARK 470     ASN C 202    CG   OD1  ND2                                       
REMARK 470     LYS C 204    CG   CD   CE   NZ                                   
REMARK 470     SER C 206    OG                                                  
REMARK 470     ARG C 210    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP C 237    CG   OD1  OD2                                       
REMARK 470     CYS C 242    SG                                                  
REMARK 470     LEU C 243    CG   CD1  CD2                                       
REMARK 470     THR C 267    OG1  CG2                                            
REMARK 470     ASP C 281    CG   OD1  OD2                                       
REMARK 470     GLU C 282    CG   CD   OE1  OE2                                  
REMARK 470     LYS C 283    CG   CD   CE   NZ                                   
REMARK 470     GLU C 289    CG   CD   OE1  OE2                                  
REMARK 470     THR C 292    OG1  CG2                                            
REMARK 470     GLN C 295    CG   CD   OE1  NE2                                  
REMARK 470     CYS C 298    SG                                                  
REMARK 470     GLU C 316    CG   CD   OE1  OE2                                  
REMARK 470     ASP C 317    CG   OD1  OD2                                       
REMARK 470     THR C 318    O    OG1  CG2                                       
REMARK 470     ARG C 327    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG C 334    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ILE C 335    CG1  CG2  CD1                                       
REMARK 470     ARG C 336    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG C 337    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     PHE C 338    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     PHE C 339    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     LYS C 341    CG   CD   CE   NZ                                   
REMARK 470     LEU C 344    CG   CD1  CD2                                       
REMARK 470     GLU C 345    CG   CD   OE1  OE2                                  
REMARK 470     GLN C 348    CG   CD   OE1  NE2                                  
REMARK 470     GLN C 350    CG   CD   OE1  NE2                                  
REMARK 470     GLU C 352    CG   CD   OE1  OE2                                  
REMARK 470     LYS C 358    CG   CD   CE   NZ                                   
REMARK 470     GLU C 359    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 367    CG   CD   OE1  OE2                                  
REMARK 470     ASP C 368    CG   OD1  OD2                                       
REMARK 470     SER C 370    OG                                                  
REMARK 470     GLU C 371    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 372    CG   CD   OE1  OE2                                  
REMARK 470     CYS C 385    SG                                                  
REMARK 470     SER C 387    O    OG                                             
REMARK 470     TYR C 393    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     GLU C 412    CG   CD   OE1  OE2                                  
REMARK 470     LEU C 413    CG   CD1  CD2                                       
REMARK 470     PHE C 414    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ARG C 415    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP C 417    CG   OD1  OD2                                       
REMARK 470     ILE C 418    CG1  CG2  CD1                                       
REMARK 470     GLN C 419    CG   CD   OE1  NE2                                  
REMARK 470     GLU C 426    CG   CD   OE1  OE2                                  
REMARK 470     ASP C 436    CG   OD1  OD2                                       
REMARK 470     GLU C 439    CG   CD   OE1  OE2                                  
REMARK 470     SER C 450    OG                                                  
REMARK 470     MET C 458    CG   SD   CE                                        
REMARK 470     GLN C 462    CG   CD   OE1  NE2                                  
REMARK 470     SER C 469    OG                                                  
REMARK 470     ASN C 470    CG   OD1  ND2                                       
REMARK 470     SER C 471    OG                                                  
REMARK 470     ASP C 478    CG   OD1  OD2                                       
REMARK 470     GLN C 479    CG   CD   OE1  NE2                                  
REMARK 470     ASP C 561    CG   OD1  OD2                                       
REMARK 470     GLU C 580    CG   CD   OE1  OE2                                  
REMARK 470     SER C 583    OG                                                  
REMARK 470     MET C 599    CG   SD   CE                                        
REMARK 470     GLU C 603    CG   CD   OE1  OE2                                  
REMARK 470     ASP C 605    CG   OD1  OD2                                       
REMARK 470     GLU C 607    CG   CD   OE1  OE2                                  
REMARK 470     ARG C 611    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU C 629    CG   CD   OE1  OE2                                  
REMARK 470     SER C 634    OG                                                  
REMARK 470     LEU C 648    CG   CD1  CD2                                       
REMARK 470     ASP C 651    CG   OD1  OD2                                       
REMARK 470     ASP C 662    CG   OD1  OD2                                       
REMARK 470     ASP C 683    CG   OD1  OD2                                       
REMARK 470     MET C 684    CG   SD   CE                                        
REMARK 470     SER C 686    OG                                                  
REMARK 470     LEU C 695    CG   CD1  CD2                                       
REMARK 470     PHE C 698    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     THR C 705    OG1  CG2                                            
REMARK 470     ARG C 706    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU C 707    CG   CD1  CD2                                       
REMARK 470     ILE C 708    CG1  CG2  CD1                                       
REMARK 470     THR C 709    OG1  CG2                                            
REMARK 470     ARG C 766    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG C 767    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     CYS C 768    SG                                                  
REMARK 470     ARG C 770    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     PHE C 773    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLN C 806    CG   CD   OE1  NE2                                  
REMARK 470     CYS C 826    SG                                                  
REMARK 470     GLU C 827    CG   CD   OE1  OE2                                  
REMARK 470     GLU C 828    CG   CD   OE1  OE2                                  
REMARK 470     SER C 842    OG                                                  
REMARK 470     HIS C 849    CG   ND1  CD2  CE1  NE2                             
REMARK 470     SER C 851    OG                                                  
REMARK 470     ASP C 868    CG   OD1  OD2                                       
REMARK 470     LEU C 883    CG   CD1  CD2                                       
REMARK 470     ASP C 956    CG   OD1  OD2                                       
REMARK 470     SER C 957    OG                                                  
REMARK 470     GLU C 989    CG   CD   OE1  OE2                                  
REMARK 470     ASN C 992    CG   OD1  ND2                                       
REMARK 470     CYS C 993    SG                                                  
REMARK 470     SER C 995    OG                                                  
REMARK 470     GLU C 996    CG   CD   OE1  OE2                                  
REMARK 470     ARG C1072    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU C1075    CG   CD1  CD2                                       
REMARK 470     PHE C1079    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ILE C1080    CG1  CG2  CD1                                       
REMARK 470     VAL C1081    CG1  CG2                                            
REMARK 470     ILE C1082    CG1  CG2  CD1                                       
REMARK 470     SER C1083    OG                                                  
REMARK 470     HIS C1084    CG   ND1  CD2  CE1  NE2                             
REMARK 470     LEU C1085    CG   CD1  CD2                                       
REMARK 470     ARG C1086    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU C1087    CG   CD1  CD2                                       
REMARK 470     LEU C1088    CG   CD1  CD2                                       
REMARK 470     LEU C1089    CG   CD1  CD2                                       
REMARK 470     ARG C1090    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLN C1091    O    CG   CD   OE1  NE2                             
REMARK 470     GLU C1107    CG   CD   OE1  OE2                                  
REMARK 470     HIS C1108    CG   ND1  CD2  CE1  NE2                             
REMARK 470     PHE C1109    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ARG C1110    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU C1116    CG   CD   OE1  OE2                                  
REMARK 470     GLU C1130    CG   CD   OE1  OE2                                  
REMARK 470     GLU C1142    CG   CD   OE1  OE2                                  
REMARK 470     ASP C1156    CG   OD1  OD2                                       
REMARK 470     GLN C1170    CG   CD   OE1  NE2                                  
REMARK 470     ARG C1171    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS C1173    CG   CD   CE   NZ                                   
REMARK 470     VAL C1174    CG1  CG2                                            
REMARK 470     LEU C1175    CG   CD1  CD2                                       
REMARK 470     GLU C1176    CG   CD   OE1  OE2                                  
REMARK 470     ARG C1177    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU C1178    CG   CD   OE1  OE2                                  
REMARK 470     VAL C1179    CG1  CG2                                            
REMARK 470     GLN C1180    CG   CD   OE1  NE2                                  
REMARK 470     GLN C1181    CG   CD   OE1  NE2                                  
REMARK 470     CYS C1182    SG                                                  
REMARK 470     SER C1183    OG                                                  
REMARK 470     ARG C1184    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     VAL C1185    CG1  CG2                                            
REMARK 470     LEU C1186    CG   CD1  CD2                                       
REMARK 470     TRP C1188    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP C1188    CZ3  CH2                                            
REMARK 470     VAL C1189    CG1  CG2                                            
REMARK 470     GLU C1191    CG   CD   OE1  OE2                                  
REMARK 470     LEU C1193    O    CG   CD1  CD2                                  
REMARK 470     GLU D   7    CG   CD   OE1  OE2                                  
REMARK 470     LYS D  13    CG   CD   CE   NZ                                   
REMARK 470     CYS D  20    O    SG                                             
REMARK 470     HIS D  66    CG   ND1  CD2  CE1  NE2                             
REMARK 470     THR D  68    OG1  CG2                                            
REMARK 470     GLU D  69    CG   CD   OE1  OE2                                  
REMARK 470     GLU D  77    CG   CD   OE1  OE2                                  
REMARK 470     ARG D  85    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS D  86    CG   CD   CE   NZ                                   
REMARK 470     ARG D  96    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP D  98    CG   OD1  OD2                                       
REMARK 470     ARG D 108    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG D 113    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     SER D 125    OG                                                  
REMARK 470     ASP D 172    CG   OD1  OD2                                       
REMARK 470     MET D 175    CG   SD   CE                                        
REMARK 470     LYS D 182    CG   CD   CE   NZ                                   
REMARK 470     ASP D 198    CG   OD1  OD2                                       
REMARK 470     ASN D 202    CG   OD1  ND2                                       
REMARK 470     LYS D 204    CG   CD   CE   NZ                                   
REMARK 470     SER D 206    OG                                                  
REMARK 470     ARG D 210    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP D 237    CG   OD1  OD2                                       
REMARK 470     CYS D 242    SG                                                  
REMARK 470     LEU D 243    CG   CD1  CD2                                       
REMARK 470     THR D 267    OG1  CG2                                            
REMARK 470     ASP D 281    CG   OD1  OD2                                       
REMARK 470     GLU D 282    CG   CD   OE1  OE2                                  
REMARK 470     LYS D 283    CG   CD   CE   NZ                                   
REMARK 470     GLU D 289    CG   CD   OE1  OE2                                  
REMARK 470     THR D 292    OG1  CG2                                            
REMARK 470     GLN D 295    CG   CD   OE1  NE2                                  
REMARK 470     CYS D 298    SG                                                  
REMARK 470     GLU D 316    CG   CD   OE1  OE2                                  
REMARK 470     ASP D 317    CG   OD1  OD2                                       
REMARK 470     THR D 318    O    OG1  CG2                                       
REMARK 470     ARG D 327    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG D 334    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ILE D 335    CG1  CG2  CD1                                       
REMARK 470     ARG D 336    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG D 337    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     PHE D 338    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     PHE D 339    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     LYS D 341    CG   CD   CE   NZ                                   
REMARK 470     LEU D 344    CG   CD1  CD2                                       
REMARK 470     GLU D 345    CG   CD   OE1  OE2                                  
REMARK 470     GLN D 348    CG   CD   OE1  NE2                                  
REMARK 470     GLN D 350    CG   CD   OE1  NE2                                  
REMARK 470     GLU D 352    CG   CD   OE1  OE2                                  
REMARK 470     LYS D 358    CG   CD   CE   NZ                                   
REMARK 470     GLU D 359    CG   CD   OE1  OE2                                  
REMARK 470     GLU D 367    CG   CD   OE1  OE2                                  
REMARK 470     ASP D 368    CG   OD1  OD2                                       
REMARK 470     SER D 370    OG                                                  
REMARK 470     GLU D 371    CG   CD   OE1  OE2                                  
REMARK 470     GLU D 372    CG   CD   OE1  OE2                                  
REMARK 470     CYS D 385    SG                                                  
REMARK 470     SER D 387    O    OG                                             
REMARK 470     TYR D 393    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     GLU D 412    CG   CD   OE1  OE2                                  
REMARK 470     LEU D 413    CG   CD1  CD2                                       
REMARK 470     PHE D 414    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ARG D 415    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP D 417    CG   OD1  OD2                                       
REMARK 470     ILE D 418    CG1  CG2  CD1                                       
REMARK 470     GLN D 419    CG   CD   OE1  NE2                                  
REMARK 470     GLU D 426    CG   CD   OE1  OE2                                  
REMARK 470     ASP D 436    CG   OD1  OD2                                       
REMARK 470     GLU D 439    CG   CD   OE1  OE2                                  
REMARK 470     SER D 450    OG                                                  
REMARK 470     MET D 458    CG   SD   CE                                        
REMARK 470     GLN D 462    CG   CD   OE1  NE2                                  
REMARK 470     SER D 469    OG                                                  
REMARK 470     ASN D 470    CG   OD1  ND2                                       
REMARK 470     SER D 471    OG                                                  
REMARK 470     ASP D 478    CG   OD1  OD2                                       
REMARK 470     GLN D 479    CG   CD   OE1  NE2                                  
REMARK 470     ASP D 561    CG   OD1  OD2                                       
REMARK 470     GLU D 580    CG   CD   OE1  OE2                                  
REMARK 470     SER D 583    OG                                                  
REMARK 470     MET D 599    CG   SD   CE                                        
REMARK 470     GLU D 603    CG   CD   OE1  OE2                                  
REMARK 470     ASP D 605    CG   OD1  OD2                                       
REMARK 470     GLU D 607    CG   CD   OE1  OE2                                  
REMARK 470     ARG D 611    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU D 629    CG   CD   OE1  OE2                                  
REMARK 470     SER D 634    OG                                                  
REMARK 470     LEU D 648    CG   CD1  CD2                                       
REMARK 470     ASP D 651    CG   OD1  OD2                                       
REMARK 470     ASP D 662    CG   OD1  OD2                                       
REMARK 470     ASP D 683    CG   OD1  OD2                                       
REMARK 470     MET D 684    CG   SD   CE                                        
REMARK 470     SER D 686    OG                                                  
REMARK 470     LEU D 695    CG   CD1  CD2                                       
REMARK 470     PHE D 698    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     THR D 705    OG1  CG2                                            
REMARK 470     ARG D 706    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU D 707    CG   CD1  CD2                                       
REMARK 470     ILE D 708    CG1  CG2  CD1                                       
REMARK 470     THR D 709    OG1  CG2                                            
REMARK 470     ARG D 766    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG D 767    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     CYS D 768    SG                                                  
REMARK 470     ARG D 770    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     PHE D 773    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLN D 806    CG   CD   OE1  NE2                                  
REMARK 470     CYS D 826    SG                                                  
REMARK 470     GLU D 827    CG   CD   OE1  OE2                                  
REMARK 470     GLU D 828    CG   CD   OE1  OE2                                  
REMARK 470     SER D 842    OG                                                  
REMARK 470     HIS D 849    CG   ND1  CD2  CE1  NE2                             
REMARK 470     SER D 851    OG                                                  
REMARK 470     ASP D 868    CG   OD1  OD2                                       
REMARK 470     LEU D 883    CG   CD1  CD2                                       
REMARK 470     ASP D 956    CG   OD1  OD2                                       
REMARK 470     SER D 957    OG                                                  
REMARK 470     GLU D 989    CG   CD   OE1  OE2                                  
REMARK 470     ASN D 992    CG   OD1  ND2                                       
REMARK 470     CYS D 993    SG                                                  
REMARK 470     SER D 995    OG                                                  
REMARK 470     GLU D 996    CG   CD   OE1  OE2                                  
REMARK 470     ARG D1072    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU D1075    CG   CD1  CD2                                       
REMARK 470     PHE D1079    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ILE D1080    CG1  CG2  CD1                                       
REMARK 470     VAL D1081    CG1  CG2                                            
REMARK 470     ILE D1082    CG1  CG2  CD1                                       
REMARK 470     SER D1083    OG                                                  
REMARK 470     HIS D1084    CG   ND1  CD2  CE1  NE2                             
REMARK 470     LEU D1085    CG   CD1  CD2                                       
REMARK 470     ARG D1086    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU D1087    CG   CD1  CD2                                       
REMARK 470     LEU D1088    CG   CD1  CD2                                       
REMARK 470     LEU D1089    CG   CD1  CD2                                       
REMARK 470     ARG D1090    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLN D1091    O    CG   CD   OE1  NE2                             
REMARK 470     GLU D1107    CG   CD   OE1  OE2                                  
REMARK 470     HIS D1108    CG   ND1  CD2  CE1  NE2                             
REMARK 470     PHE D1109    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ARG D1110    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU D1116    CG   CD   OE1  OE2                                  
REMARK 470     GLU D1130    CG   CD   OE1  OE2                                  
REMARK 470     GLU D1142    CG   CD   OE1  OE2                                  
REMARK 470     ASP D1156    CG   OD1  OD2                                       
REMARK 470     GLN D1170    CG   CD   OE1  NE2                                  
REMARK 470     ARG D1171    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS D1173    CG   CD   CE   NZ                                   
REMARK 470     VAL D1174    CG1  CG2                                            
REMARK 470     LEU D1175    CG   CD1  CD2                                       
REMARK 470     GLU D1176    CG   CD   OE1  OE2                                  
REMARK 470     ARG D1177    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU D1178    CG   CD   OE1  OE2                                  
REMARK 470     VAL D1179    CG1  CG2                                            
REMARK 470     GLN D1180    CG   CD   OE1  NE2                                  
REMARK 470     GLN D1181    CG   CD   OE1  NE2                                  
REMARK 470     CYS D1182    SG                                                  
REMARK 470     SER D1183    OG                                                  
REMARK 470     ARG D1184    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     VAL D1185    CG1  CG2                                            
REMARK 470     LEU D1186    CG   CD1  CD2                                       
REMARK 470     TRP D1188    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP D1188    CZ3  CH2                                            
REMARK 470     VAL D1189    CG1  CG2                                            
REMARK 470     GLU D1191    CG   CD   OE1  OE2                                  
REMARK 470     LEU D1193    O    CG   CD1  CD2                                  
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: TORSION ANGLES                                             
REMARK 500                                                                      
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:            
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)                    
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-           
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400            
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        PSI       PHI                                   
REMARK 500    LEU A 158     -167.27    -79.48                                   
REMARK 500    THR A 181       70.19     57.22                                   
REMARK 500    TYR A 227       70.10   -112.59                                   
REMARK 500    ASN A 228       -2.10   -145.56                                   
REMARK 500    THR A 239     -178.23   -176.47                                   
REMARK 500    ASP A 279      131.70    -36.61                                   
REMARK 500    LYS A 341      -36.84   -134.64                                   
REMARK 500    GLN A 348      -62.17    -94.48                                   
REMARK 500    GLU A 371       19.97     59.81                                   
REMARK 500    SER A 634       70.77     60.21                                   
REMARK 500    MET A 684       66.49     60.61                                   
REMARK 500    ASP A 804     -154.49    -81.23                                   
REMARK 500    ARG A 953       76.34     51.30                                   
REMARK 500    ARG A 955       47.18    -90.73                                   
REMARK 500    GLN A1007       -9.55     71.02                                   
REMARK 500    ALA A1008       48.34    -96.98                                   
REMARK 500    ALA A1192       13.05   -142.43                                   
REMARK 500    LEU B 158     -167.22    -79.47                                   
REMARK 500    THR B 181       70.17     57.21                                   
REMARK 500    TYR B 227       70.15   -112.60                                   
REMARK 500    ASN B 228       -2.12   -145.59                                   
REMARK 500    THR B 239     -178.22   -176.52                                   
REMARK 500    ASP B 279      131.65    -36.58                                   
REMARK 500    LYS B 341      -36.83   -134.57                                   
REMARK 500    GLN B 348      -62.23    -94.50                                   
REMARK 500    GLU B 371       19.97     59.88                                   
REMARK 500    SER B 634       70.78     60.25                                   
REMARK 500    MET B 684       66.46     60.62                                   
REMARK 500    ASP B 804     -154.50    -81.25                                   
REMARK 500    ARG B 953       76.39     51.23                                   
REMARK 500    ARG B 955       47.17    -90.75                                   
REMARK 500    GLN B1007       -9.54     71.02                                   
REMARK 500    ALA B1008       48.30    -96.92                                   
REMARK 500    ALA B1192       13.01   -142.46                                   
REMARK 500    LEU C 158     -167.23    -79.46                                   
REMARK 500    THR C 181       70.20     57.19                                   
REMARK 500    TYR C 227       70.05   -112.59                                   
REMARK 500    ASN C 228       -2.06   -145.56                                   
REMARK 500    THR C 239     -178.21   -176.42                                   
REMARK 500    ASP C 279      131.70    -36.60                                   
REMARK 500    LYS C 341      -36.88   -134.62                                   
REMARK 500    GLN C 348      -62.20    -94.51                                   
REMARK 500    GLU C 371       19.95     59.80                                   
REMARK 500    SER C 634       70.71     60.27                                   
REMARK 500    MET C 684       66.51     60.60                                   
REMARK 500    ASP C 804     -154.48    -81.27                                   
REMARK 500    ARG C 953       76.29     51.28                                   
REMARK 500    ARG C 955       47.19    -90.78                                   
REMARK 500    GLN C1007       -9.65     71.06                                   
REMARK 500    ALA C1008       48.32    -96.88                                   
REMARK 500                                                                      
REMARK 500 THIS ENTRY HAS      68 RAMACHANDRAN OUTLIERS.                        
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 800                                                                      
REMARK 800 SITE                                                                 
REMARK 800 SITE_IDENTIFIER: AC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue DVT A 2001                
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue DVT A 2002                
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC3                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue DVT B 2001                
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC4                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue DVT B 2002                
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC5                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue DVT C 2001                
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC6                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue DVT C 2002                
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC7                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue DVT D 2001                
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC8                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue DVT D 2002                
REMARK 900                                                                      
REMARK 900 RELATED ENTRIES                                                      
REMARK 900 RELATED ID: EMD-8871   RELATED DB: EMDB                              
REMARK 900 CRYO-EM STRUCTURE OF A HUMAN TRPM4 CHANNEL IN COMPLEX WITH CALCIUM   
REMARK 900 AND DECAVANADATE                                                     
REMARK 900 RELATED ID: EMD-8873   RELATED DB: EMDB                              
REMARK 900 RELATED ID: EMD-8875   RELATED DB: EMDB                              
REMARK 900 RELATED ID: EMD-8876   RELATED DB: EMDB                              
REMARK 900 RELATED ID: EMD-8877   RELATED DB: EMDB                              
REMARK 900 RELATED ID: EMD-8878   RELATED DB: EMDB                              
REMARK 900 RELATED ID: EMD-8879   RELATED DB: EMDB                              
REMARK 900 RELATED ID: EMD-8872   RELATED DB: EMDB                              
DBREF  5WP6 A    1  1214  UNP    Q8TD43   TRPM4_HUMAN      1   1214             
DBREF  5WP6 B    1  1214  UNP    Q8TD43   TRPM4_HUMAN      1   1214             
DBREF  5WP6 C    1  1214  UNP    Q8TD43   TRPM4_HUMAN      1   1214             
DBREF  5WP6 D    1  1214  UNP    Q8TD43   TRPM4_HUMAN      1   1214             
SEQRES   1 A 1214  MET VAL VAL PRO GLU LYS GLU GLN SER TRP ILE PRO LYS          
SEQRES   2 A 1214  ILE PHE LYS LYS LYS THR CYS THR THR PHE ILE VAL ASP          
SEQRES   3 A 1214  SER THR ASP PRO GLY GLY THR LEU CYS GLN CYS GLY ARG          
SEQRES   4 A 1214  PRO ARG THR ALA HIS PRO ALA VAL ALA MET GLU ASP ALA          
SEQRES   5 A 1214  PHE GLY ALA ALA VAL VAL THR VAL TRP ASP SER ASP ALA          
SEQRES   6 A 1214  HIS THR THR GLU LYS PRO THR ASP ALA TYR GLY GLU LEU          
SEQRES   7 A 1214  ASP PHE THR GLY ALA GLY ARG LYS HIS SER ASN PHE LEU          
SEQRES   8 A 1214  ARG LEU SER ASP ARG THR ASP PRO ALA ALA VAL TYR SER          
SEQRES   9 A 1214  LEU VAL THR ARG THR TRP GLY PHE ARG ALA PRO ASN LEU          
SEQRES  10 A 1214  VAL VAL SER VAL LEU GLY GLY SER GLY GLY PRO VAL LEU          
SEQRES  11 A 1214  GLN THR TRP LEU GLN ASP LEU LEU ARG ARG GLY LEU VAL          
SEQRES  12 A 1214  ARG ALA ALA GLN SER THR GLY ALA TRP ILE VAL THR GLY          
SEQRES  13 A 1214  GLY LEU HIS THR GLY ILE GLY ARG HIS VAL GLY VAL ALA          
SEQRES  14 A 1214  VAL ARG ASP HIS GLN MET ALA SER THR GLY GLY THR LYS          
SEQRES  15 A 1214  VAL VAL ALA MET GLY VAL ALA PRO TRP GLY VAL VAL ARG          
SEQRES  16 A 1214  ASN ARG ASP THR LEU ILE ASN PRO LYS GLY SER PHE PRO          
SEQRES  17 A 1214  ALA ARG TYR ARG TRP ARG GLY ASP PRO GLU ASP GLY VAL          
SEQRES  18 A 1214  GLN PHE PRO LEU ASP TYR ASN TYR SER ALA PHE PHE LEU          
SEQRES  19 A 1214  VAL ASP ASP GLY THR HIS GLY CYS LEU GLY GLY GLU ASN          
SEQRES  20 A 1214  ARG PHE ARG LEU ARG LEU GLU SER TYR ILE SER GLN GLN          
SEQRES  21 A 1214  LYS THR GLY VAL GLY GLY THR GLY ILE ASP ILE PRO VAL          
SEQRES  22 A 1214  LEU LEU LEU LEU ILE ASP GLY ASP GLU LYS MET LEU THR          
SEQRES  23 A 1214  ARG ILE GLU ASN ALA THR GLN ALA GLN LEU PRO CYS LEU          
SEQRES  24 A 1214  LEU VAL ALA GLY SER GLY GLY ALA ALA ASP CYS LEU ALA          
SEQRES  25 A 1214  GLU THR LEU GLU ASP THR LEU ALA PRO GLY SER GLY GLY          
SEQRES  26 A 1214  ALA ARG GLN GLY GLU ALA ARG ASP ARG ILE ARG ARG PHE          
SEQRES  27 A 1214  PHE PRO LYS GLY ASP LEU GLU VAL LEU GLN ALA GLN VAL          
SEQRES  28 A 1214  GLU ARG ILE MET THR ARG LYS GLU LEU LEU THR VAL TYR          
SEQRES  29 A 1214  SER SER GLU ASP GLY SER GLU GLU PHE GLU THR ILE VAL          
SEQRES  30 A 1214  LEU LYS ALA LEU VAL LYS ALA CYS GLY SER SER GLU ALA          
SEQRES  31 A 1214  SER ALA TYR LEU ASP GLU LEU ARG LEU ALA VAL ALA TRP          
SEQRES  32 A 1214  ASN ARG VAL ASP ILE ALA GLN SER GLU LEU PHE ARG GLY          
SEQRES  33 A 1214  ASP ILE GLN TRP ARG SER PHE HIS LEU GLU ALA SER LEU          
SEQRES  34 A 1214  MET ASP ALA LEU LEU ASN ASP ARG PRO GLU PHE VAL ARG          
SEQRES  35 A 1214  LEU LEU ILE SER HIS GLY LEU SER LEU GLY HIS PHE LEU          
SEQRES  36 A 1214  THR PRO MET ARG LEU ALA GLN LEU TYR SER ALA ALA PRO          
SEQRES  37 A 1214  SER ASN SER LEU ILE ARG ASN LEU LEU ASP GLN ALA SER          
SEQRES  38 A 1214  HIS SER ALA GLY THR LYS ALA PRO ALA LEU LYS GLY GLY          
SEQRES  39 A 1214  ALA ALA GLU LEU ARG PRO PRO ASP VAL GLY HIS VAL LEU          
SEQRES  40 A 1214  ARG MET LEU LEU GLY LYS MET CYS ALA PRO ARG TYR PRO          
SEQRES  41 A 1214  SER GLY GLY ALA TRP ASP PRO HIS PRO GLY GLN GLY PHE          
SEQRES  42 A 1214  GLY GLU SER MET TYR LEU LEU SER ASP LYS ALA THR SER          
SEQRES  43 A 1214  PRO LEU SER LEU ASP ALA GLY LEU GLY GLN ALA PRO TRP          
SEQRES  44 A 1214  SER ASP LEU LEU LEU TRP ALA LEU LEU LEU ASN ARG ALA          
SEQRES  45 A 1214  GLN MET ALA MET TYR PHE TRP GLU MET GLY SER ASN ALA          
SEQRES  46 A 1214  VAL SER SER ALA LEU GLY ALA CYS LEU LEU LEU ARG VAL          
SEQRES  47 A 1214  MET ALA ARG LEU GLU PRO ASP ALA GLU GLU ALA ALA ARG          
SEQRES  48 A 1214  ARG LYS ASP LEU ALA PHE LYS PHE GLU GLY MET GLY VAL          
SEQRES  49 A 1214  ASP LEU PHE GLY GLU CYS TYR ARG SER SER GLU VAL ARG          
SEQRES  50 A 1214  ALA ALA ARG LEU LEU LEU ARG ARG CYS PRO LEU TRP GLY          
SEQRES  51 A 1214  ASP ALA THR CYS LEU GLN LEU ALA MET GLN ALA ASP ALA          
SEQRES  52 A 1214  ARG ALA PHE PHE ALA GLN ASP GLY VAL GLN SER LEU LEU          
SEQRES  53 A 1214  THR GLN LYS TRP TRP GLY ASP MET ALA SER THR THR PRO          
SEQRES  54 A 1214  ILE TRP ALA LEU VAL LEU ALA PHE PHE CYS PRO PRO LEU          
SEQRES  55 A 1214  ILE TYR THR ARG LEU ILE THR PHE ARG LYS SER GLU GLU          
SEQRES  56 A 1214  GLU PRO THR ARG GLU GLU LEU GLU PHE ASP MET ASP SER          
SEQRES  57 A 1214  VAL ILE ASN GLY GLU GLY PRO VAL GLY THR ALA ASP PRO          
SEQRES  58 A 1214  ALA GLU LYS THR PRO LEU GLY VAL PRO ARG GLN SER GLY          
SEQRES  59 A 1214  ARG PRO GLY CYS CYS GLY GLY ARG CYS GLY GLY ARG ARG          
SEQRES  60 A 1214  CYS LEU ARG ARG TRP PHE HIS PHE TRP GLY ALA PRO VAL          
SEQRES  61 A 1214  THR ILE PHE MET GLY ASN VAL VAL SER TYR LEU LEU PHE          
SEQRES  62 A 1214  LEU LEU LEU PHE SER ARG VAL LEU LEU VAL ASP PHE GLN          
SEQRES  63 A 1214  PRO ALA PRO PRO GLY SER LEU GLU LEU LEU LEU TYR PHE          
SEQRES  64 A 1214  TRP ALA PHE THR LEU LEU CYS GLU GLU LEU ARG GLN GLY          
SEQRES  65 A 1214  LEU SER GLY GLY GLY GLY SER LEU ALA SER GLY GLY PRO          
SEQRES  66 A 1214  GLY PRO GLY HIS ALA SER LEU SER GLN ARG LEU ARG LEU          
SEQRES  67 A 1214  TYR LEU ALA ASP SER TRP ASN GLN CYS ASP LEU VAL ALA          
SEQRES  68 A 1214  LEU THR CYS PHE LEU LEU GLY VAL GLY CYS ARG LEU THR          
SEQRES  69 A 1214  PRO GLY LEU TYR HIS LEU GLY ARG THR VAL LEU CYS ILE          
SEQRES  70 A 1214  ASP PHE MET VAL PHE THR VAL ARG LEU LEU HIS ILE PHE          
SEQRES  71 A 1214  THR VAL ASN LYS GLN LEU GLY PRO LYS ILE VAL ILE VAL          
SEQRES  72 A 1214  SER LYS MET MET LYS ASP VAL PHE PHE PHE LEU PHE PHE          
SEQRES  73 A 1214  LEU GLY VAL TRP LEU VAL ALA TYR GLY VAL ALA THR GLU          
SEQRES  74 A 1214  GLY LEU LEU ARG PRO ARG ASP SER ASP PHE PRO SER ILE          
SEQRES  75 A 1214  LEU ARG ARG VAL PHE TYR ARG PRO TYR LEU GLN ILE PHE          
SEQRES  76 A 1214  GLY GLN ILE PRO GLN GLU ASP MET ASP VAL ALA LEU MET          
SEQRES  77 A 1214  GLU HIS SER ASN CYS SER SER GLU PRO GLY PHE TRP ALA          
SEQRES  78 A 1214  HIS PRO PRO GLY ALA GLN ALA GLY THR CYS VAL SER GLN          
SEQRES  79 A 1214  TYR ALA ASN TRP LEU VAL VAL LEU LEU LEU VAL ILE PHE          
SEQRES  80 A 1214  LEU LEU VAL ALA ASN ILE LEU LEU VAL ASN LEU LEU ILE          
SEQRES  81 A 1214  ALA MET PHE SER TYR THR PHE GLY LYS VAL GLN GLY ASN          
SEQRES  82 A 1214  SER ASP LEU TYR TRP LYS ALA GLN ARG TYR ARG LEU ILE          
SEQRES  83 A 1214  ARG GLU PHE HIS SER ARG PRO ALA LEU ALA PRO PRO PHE          
SEQRES  84 A 1214  ILE VAL ILE SER HIS LEU ARG LEU LEU LEU ARG GLN LEU          
SEQRES  85 A 1214  CYS ARG ARG PRO ARG SER PRO GLN PRO SER SER PRO ALA          
SEQRES  86 A 1214  LEU GLU HIS PHE ARG VAL TYR LEU SER LYS GLU ALA GLU          
SEQRES  87 A 1214  ARG LYS LEU LEU THR TRP GLU SER VAL HIS LYS GLU ASN          
SEQRES  88 A 1214  PHE LEU LEU ALA ARG ALA ARG ASP LYS ARG GLU SER ASP          
SEQRES  89 A 1214  SER GLU ARG LEU LYS ARG THR SER GLN LYS VAL ASP LEU          
SEQRES  90 A 1214  ALA LEU LYS GLN LEU GLY HIS ILE ARG GLU TYR GLU GLN          
SEQRES  91 A 1214  ARG LEU LYS VAL LEU GLU ARG GLU VAL GLN GLN CYS SER          
SEQRES  92 A 1214  ARG VAL LEU GLY TRP VAL ALA GLU ALA LEU SER ARG SER          
SEQRES  93 A 1214  ALA LEU LEU PRO PRO GLY GLY PRO PRO PRO PRO ASP LEU          
SEQRES  94 A 1214  PRO GLY SER LYS ASP                                          
SEQRES   1 B 1214  MET VAL VAL PRO GLU LYS GLU GLN SER TRP ILE PRO LYS          
SEQRES   2 B 1214  ILE PHE LYS LYS LYS THR CYS THR THR PHE ILE VAL ASP          
SEQRES   3 B 1214  SER THR ASP PRO GLY GLY THR LEU CYS GLN CYS GLY ARG          
SEQRES   4 B 1214  PRO ARG THR ALA HIS PRO ALA VAL ALA MET GLU ASP ALA          
SEQRES   5 B 1214  PHE GLY ALA ALA VAL VAL THR VAL TRP ASP SER ASP ALA          
SEQRES   6 B 1214  HIS THR THR GLU LYS PRO THR ASP ALA TYR GLY GLU LEU          
SEQRES   7 B 1214  ASP PHE THR GLY ALA GLY ARG LYS HIS SER ASN PHE LEU          
SEQRES   8 B 1214  ARG LEU SER ASP ARG THR ASP PRO ALA ALA VAL TYR SER          
SEQRES   9 B 1214  LEU VAL THR ARG THR TRP GLY PHE ARG ALA PRO ASN LEU          
SEQRES  10 B 1214  VAL VAL SER VAL LEU GLY GLY SER GLY GLY PRO VAL LEU          
SEQRES  11 B 1214  GLN THR TRP LEU GLN ASP LEU LEU ARG ARG GLY LEU VAL          
SEQRES  12 B 1214  ARG ALA ALA GLN SER THR GLY ALA TRP ILE VAL THR GLY          
SEQRES  13 B 1214  GLY LEU HIS THR GLY ILE GLY ARG HIS VAL GLY VAL ALA          
SEQRES  14 B 1214  VAL ARG ASP HIS GLN MET ALA SER THR GLY GLY THR LYS          
SEQRES  15 B 1214  VAL VAL ALA MET GLY VAL ALA PRO TRP GLY VAL VAL ARG          
SEQRES  16 B 1214  ASN ARG ASP THR LEU ILE ASN PRO LYS GLY SER PHE PRO          
SEQRES  17 B 1214  ALA ARG TYR ARG TRP ARG GLY ASP PRO GLU ASP GLY VAL          
SEQRES  18 B 1214  GLN PHE PRO LEU ASP TYR ASN TYR SER ALA PHE PHE LEU          
SEQRES  19 B 1214  VAL ASP ASP GLY THR HIS GLY CYS LEU GLY GLY GLU ASN          
SEQRES  20 B 1214  ARG PHE ARG LEU ARG LEU GLU SER TYR ILE SER GLN GLN          
SEQRES  21 B 1214  LYS THR GLY VAL GLY GLY THR GLY ILE ASP ILE PRO VAL          
SEQRES  22 B 1214  LEU LEU LEU LEU ILE ASP GLY ASP GLU LYS MET LEU THR          
SEQRES  23 B 1214  ARG ILE GLU ASN ALA THR GLN ALA GLN LEU PRO CYS LEU          
SEQRES  24 B 1214  LEU VAL ALA GLY SER GLY GLY ALA ALA ASP CYS LEU ALA          
SEQRES  25 B 1214  GLU THR LEU GLU ASP THR LEU ALA PRO GLY SER GLY GLY          
SEQRES  26 B 1214  ALA ARG GLN GLY GLU ALA ARG ASP ARG ILE ARG ARG PHE          
SEQRES  27 B 1214  PHE PRO LYS GLY ASP LEU GLU VAL LEU GLN ALA GLN VAL          
SEQRES  28 B 1214  GLU ARG ILE MET THR ARG LYS GLU LEU LEU THR VAL TYR          
SEQRES  29 B 1214  SER SER GLU ASP GLY SER GLU GLU PHE GLU THR ILE VAL          
SEQRES  30 B 1214  LEU LYS ALA LEU VAL LYS ALA CYS GLY SER SER GLU ALA          
SEQRES  31 B 1214  SER ALA TYR LEU ASP GLU LEU ARG LEU ALA VAL ALA TRP          
SEQRES  32 B 1214  ASN ARG VAL ASP ILE ALA GLN SER GLU LEU PHE ARG GLY          
SEQRES  33 B 1214  ASP ILE GLN TRP ARG SER PHE HIS LEU GLU ALA SER LEU          
SEQRES  34 B 1214  MET ASP ALA LEU LEU ASN ASP ARG PRO GLU PHE VAL ARG          
SEQRES  35 B 1214  LEU LEU ILE SER HIS GLY LEU SER LEU GLY HIS PHE LEU          
SEQRES  36 B 1214  THR PRO MET ARG LEU ALA GLN LEU TYR SER ALA ALA PRO          
SEQRES  37 B 1214  SER ASN SER LEU ILE ARG ASN LEU LEU ASP GLN ALA SER          
SEQRES  38 B 1214  HIS SER ALA GLY THR LYS ALA PRO ALA LEU LYS GLY GLY          
SEQRES  39 B 1214  ALA ALA GLU LEU ARG PRO PRO ASP VAL GLY HIS VAL LEU          
SEQRES  40 B 1214  ARG MET LEU LEU GLY LYS MET CYS ALA PRO ARG TYR PRO          
SEQRES  41 B 1214  SER GLY GLY ALA TRP ASP PRO HIS PRO GLY GLN GLY PHE          
SEQRES  42 B 1214  GLY GLU SER MET TYR LEU LEU SER ASP LYS ALA THR SER          
SEQRES  43 B 1214  PRO LEU SER LEU ASP ALA GLY LEU GLY GLN ALA PRO TRP          
SEQRES  44 B 1214  SER ASP LEU LEU LEU TRP ALA LEU LEU LEU ASN ARG ALA          
SEQRES  45 B 1214  GLN MET ALA MET TYR PHE TRP GLU MET GLY SER ASN ALA          
SEQRES  46 B 1214  VAL SER SER ALA LEU GLY ALA CYS LEU LEU LEU ARG VAL          
SEQRES  47 B 1214  MET ALA ARG LEU GLU PRO ASP ALA GLU GLU ALA ALA ARG          
SEQRES  48 B 1214  ARG LYS ASP LEU ALA PHE LYS PHE GLU GLY MET GLY VAL          
SEQRES  49 B 1214  ASP LEU PHE GLY GLU CYS TYR ARG SER SER GLU VAL ARG          
SEQRES  50 B 1214  ALA ALA ARG LEU LEU LEU ARG ARG CYS PRO LEU TRP GLY          
SEQRES  51 B 1214  ASP ALA THR CYS LEU GLN LEU ALA MET GLN ALA ASP ALA          
SEQRES  52 B 1214  ARG ALA PHE PHE ALA GLN ASP GLY VAL GLN SER LEU LEU          
SEQRES  53 B 1214  THR GLN LYS TRP TRP GLY ASP MET ALA SER THR THR PRO          
SEQRES  54 B 1214  ILE TRP ALA LEU VAL LEU ALA PHE PHE CYS PRO PRO LEU          
SEQRES  55 B 1214  ILE TYR THR ARG LEU ILE THR PHE ARG LYS SER GLU GLU          
SEQRES  56 B 1214  GLU PRO THR ARG GLU GLU LEU GLU PHE ASP MET ASP SER          
SEQRES  57 B 1214  VAL ILE ASN GLY GLU GLY PRO VAL GLY THR ALA ASP PRO          
SEQRES  58 B 1214  ALA GLU LYS THR PRO LEU GLY VAL PRO ARG GLN SER GLY          
SEQRES  59 B 1214  ARG PRO GLY CYS CYS GLY GLY ARG CYS GLY GLY ARG ARG          
SEQRES  60 B 1214  CYS LEU ARG ARG TRP PHE HIS PHE TRP GLY ALA PRO VAL          
SEQRES  61 B 1214  THR ILE PHE MET GLY ASN VAL VAL SER TYR LEU LEU PHE          
SEQRES  62 B 1214  LEU LEU LEU PHE SER ARG VAL LEU LEU VAL ASP PHE GLN          
SEQRES  63 B 1214  PRO ALA PRO PRO GLY SER LEU GLU LEU LEU LEU TYR PHE          
SEQRES  64 B 1214  TRP ALA PHE THR LEU LEU CYS GLU GLU LEU ARG GLN GLY          
SEQRES  65 B 1214  LEU SER GLY GLY GLY GLY SER LEU ALA SER GLY GLY PRO          
SEQRES  66 B 1214  GLY PRO GLY HIS ALA SER LEU SER GLN ARG LEU ARG LEU          
SEQRES  67 B 1214  TYR LEU ALA ASP SER TRP ASN GLN CYS ASP LEU VAL ALA          
SEQRES  68 B 1214  LEU THR CYS PHE LEU LEU GLY VAL GLY CYS ARG LEU THR          
SEQRES  69 B 1214  PRO GLY LEU TYR HIS LEU GLY ARG THR VAL LEU CYS ILE          
SEQRES  70 B 1214  ASP PHE MET VAL PHE THR VAL ARG LEU LEU HIS ILE PHE          
SEQRES  71 B 1214  THR VAL ASN LYS GLN LEU GLY PRO LYS ILE VAL ILE VAL          
SEQRES  72 B 1214  SER LYS MET MET LYS ASP VAL PHE PHE PHE LEU PHE PHE          
SEQRES  73 B 1214  LEU GLY VAL TRP LEU VAL ALA TYR GLY VAL ALA THR GLU          
SEQRES  74 B 1214  GLY LEU LEU ARG PRO ARG ASP SER ASP PHE PRO SER ILE          
SEQRES  75 B 1214  LEU ARG ARG VAL PHE TYR ARG PRO TYR LEU GLN ILE PHE          
SEQRES  76 B 1214  GLY GLN ILE PRO GLN GLU ASP MET ASP VAL ALA LEU MET          
SEQRES  77 B 1214  GLU HIS SER ASN CYS SER SER GLU PRO GLY PHE TRP ALA          
SEQRES  78 B 1214  HIS PRO PRO GLY ALA GLN ALA GLY THR CYS VAL SER GLN          
SEQRES  79 B 1214  TYR ALA ASN TRP LEU VAL VAL LEU LEU LEU VAL ILE PHE          
SEQRES  80 B 1214  LEU LEU VAL ALA ASN ILE LEU LEU VAL ASN LEU LEU ILE          
SEQRES  81 B 1214  ALA MET PHE SER TYR THR PHE GLY LYS VAL GLN GLY ASN          
SEQRES  82 B 1214  SER ASP LEU TYR TRP LYS ALA GLN ARG TYR ARG LEU ILE          
SEQRES  83 B 1214  ARG GLU PHE HIS SER ARG PRO ALA LEU ALA PRO PRO PHE          
SEQRES  84 B 1214  ILE VAL ILE SER HIS LEU ARG LEU LEU LEU ARG GLN LEU          
SEQRES  85 B 1214  CYS ARG ARG PRO ARG SER PRO GLN PRO SER SER PRO ALA          
SEQRES  86 B 1214  LEU GLU HIS PHE ARG VAL TYR LEU SER LYS GLU ALA GLU          
SEQRES  87 B 1214  ARG LYS LEU LEU THR TRP GLU SER VAL HIS LYS GLU ASN          
SEQRES  88 B 1214  PHE LEU LEU ALA ARG ALA ARG ASP LYS ARG GLU SER ASP          
SEQRES  89 B 1214  SER GLU ARG LEU LYS ARG THR SER GLN LYS VAL ASP LEU          
SEQRES  90 B 1214  ALA LEU LYS GLN LEU GLY HIS ILE ARG GLU TYR GLU GLN          
SEQRES  91 B 1214  ARG LEU LYS VAL LEU GLU ARG GLU VAL GLN GLN CYS SER          
SEQRES  92 B 1214  ARG VAL LEU GLY TRP VAL ALA GLU ALA LEU SER ARG SER          
SEQRES  93 B 1214  ALA LEU LEU PRO PRO GLY GLY PRO PRO PRO PRO ASP LEU          
SEQRES  94 B 1214  PRO GLY SER LYS ASP                                          
SEQRES   1 C 1214  MET VAL VAL PRO GLU LYS GLU GLN SER TRP ILE PRO LYS          
SEQRES   2 C 1214  ILE PHE LYS LYS LYS THR CYS THR THR PHE ILE VAL ASP          
SEQRES   3 C 1214  SER THR ASP PRO GLY GLY THR LEU CYS GLN CYS GLY ARG          
SEQRES   4 C 1214  PRO ARG THR ALA HIS PRO ALA VAL ALA MET GLU ASP ALA          
SEQRES   5 C 1214  PHE GLY ALA ALA VAL VAL THR VAL TRP ASP SER ASP ALA          
SEQRES   6 C 1214  HIS THR THR GLU LYS PRO THR ASP ALA TYR GLY GLU LEU          
SEQRES   7 C 1214  ASP PHE THR GLY ALA GLY ARG LYS HIS SER ASN PHE LEU          
SEQRES   8 C 1214  ARG LEU SER ASP ARG THR ASP PRO ALA ALA VAL TYR SER          
SEQRES   9 C 1214  LEU VAL THR ARG THR TRP GLY PHE ARG ALA PRO ASN LEU          
SEQRES  10 C 1214  VAL VAL SER VAL LEU GLY GLY SER GLY GLY PRO VAL LEU          
SEQRES  11 C 1214  GLN THR TRP LEU GLN ASP LEU LEU ARG ARG GLY LEU VAL          
SEQRES  12 C 1214  ARG ALA ALA GLN SER THR GLY ALA TRP ILE VAL THR GLY          
SEQRES  13 C 1214  GLY LEU HIS THR GLY ILE GLY ARG HIS VAL GLY VAL ALA          
SEQRES  14 C 1214  VAL ARG ASP HIS GLN MET ALA SER THR GLY GLY THR LYS          
SEQRES  15 C 1214  VAL VAL ALA MET GLY VAL ALA PRO TRP GLY VAL VAL ARG          
SEQRES  16 C 1214  ASN ARG ASP THR LEU ILE ASN PRO LYS GLY SER PHE PRO          
SEQRES  17 C 1214  ALA ARG TYR ARG TRP ARG GLY ASP PRO GLU ASP GLY VAL          
SEQRES  18 C 1214  GLN PHE PRO LEU ASP TYR ASN TYR SER ALA PHE PHE LEU          
SEQRES  19 C 1214  VAL ASP ASP GLY THR HIS GLY CYS LEU GLY GLY GLU ASN          
SEQRES  20 C 1214  ARG PHE ARG LEU ARG LEU GLU SER TYR ILE SER GLN GLN          
SEQRES  21 C 1214  LYS THR GLY VAL GLY GLY THR GLY ILE ASP ILE PRO VAL          
SEQRES  22 C 1214  LEU LEU LEU LEU ILE ASP GLY ASP GLU LYS MET LEU THR          
SEQRES  23 C 1214  ARG ILE GLU ASN ALA THR GLN ALA GLN LEU PRO CYS LEU          
SEQRES  24 C 1214  LEU VAL ALA GLY SER GLY GLY ALA ALA ASP CYS LEU ALA          
SEQRES  25 C 1214  GLU THR LEU GLU ASP THR LEU ALA PRO GLY SER GLY GLY          
SEQRES  26 C 1214  ALA ARG GLN GLY GLU ALA ARG ASP ARG ILE ARG ARG PHE          
SEQRES  27 C 1214  PHE PRO LYS GLY ASP LEU GLU VAL LEU GLN ALA GLN VAL          
SEQRES  28 C 1214  GLU ARG ILE MET THR ARG LYS GLU LEU LEU THR VAL TYR          
SEQRES  29 C 1214  SER SER GLU ASP GLY SER GLU GLU PHE GLU THR ILE VAL          
SEQRES  30 C 1214  LEU LYS ALA LEU VAL LYS ALA CYS GLY SER SER GLU ALA          
SEQRES  31 C 1214  SER ALA TYR LEU ASP GLU LEU ARG LEU ALA VAL ALA TRP          
SEQRES  32 C 1214  ASN ARG VAL ASP ILE ALA GLN SER GLU LEU PHE ARG GLY          
SEQRES  33 C 1214  ASP ILE GLN TRP ARG SER PHE HIS LEU GLU ALA SER LEU          
SEQRES  34 C 1214  MET ASP ALA LEU LEU ASN ASP ARG PRO GLU PHE VAL ARG          
SEQRES  35 C 1214  LEU LEU ILE SER HIS GLY LEU SER LEU GLY HIS PHE LEU          
SEQRES  36 C 1214  THR PRO MET ARG LEU ALA GLN LEU TYR SER ALA ALA PRO          
SEQRES  37 C 1214  SER ASN SER LEU ILE ARG ASN LEU LEU ASP GLN ALA SER          
SEQRES  38 C 1214  HIS SER ALA GLY THR LYS ALA PRO ALA LEU LYS GLY GLY          
SEQRES  39 C 1214  ALA ALA GLU LEU ARG PRO PRO ASP VAL GLY HIS VAL LEU          
SEQRES  40 C 1214  ARG MET LEU LEU GLY LYS MET CYS ALA PRO ARG TYR PRO          
SEQRES  41 C 1214  SER GLY GLY ALA TRP ASP PRO HIS PRO GLY GLN GLY PHE          
SEQRES  42 C 1214  GLY GLU SER MET TYR LEU LEU SER ASP LYS ALA THR SER          
SEQRES  43 C 1214  PRO LEU SER LEU ASP ALA GLY LEU GLY GLN ALA PRO TRP          
SEQRES  44 C 1214  SER ASP LEU LEU LEU TRP ALA LEU LEU LEU ASN ARG ALA          
SEQRES  45 C 1214  GLN MET ALA MET TYR PHE TRP GLU MET GLY SER ASN ALA          
SEQRES  46 C 1214  VAL SER SER ALA LEU GLY ALA CYS LEU LEU LEU ARG VAL          
SEQRES  47 C 1214  MET ALA ARG LEU GLU PRO ASP ALA GLU GLU ALA ALA ARG          
SEQRES  48 C 1214  ARG LYS ASP LEU ALA PHE LYS PHE GLU GLY MET GLY VAL          
SEQRES  49 C 1214  ASP LEU PHE GLY GLU CYS TYR ARG SER SER GLU VAL ARG          
SEQRES  50 C 1214  ALA ALA ARG LEU LEU LEU ARG ARG CYS PRO LEU TRP GLY          
SEQRES  51 C 1214  ASP ALA THR CYS LEU GLN LEU ALA MET GLN ALA ASP ALA          
SEQRES  52 C 1214  ARG ALA PHE PHE ALA GLN ASP GLY VAL GLN SER LEU LEU          
SEQRES  53 C 1214  THR GLN LYS TRP TRP GLY ASP MET ALA SER THR THR PRO          
SEQRES  54 C 1214  ILE TRP ALA LEU VAL LEU ALA PHE PHE CYS PRO PRO LEU          
SEQRES  55 C 1214  ILE TYR THR ARG LEU ILE THR PHE ARG LYS SER GLU GLU          
SEQRES  56 C 1214  GLU PRO THR ARG GLU GLU LEU GLU PHE ASP MET ASP SER          
SEQRES  57 C 1214  VAL ILE ASN GLY GLU GLY PRO VAL GLY THR ALA ASP PRO          
SEQRES  58 C 1214  ALA GLU LYS THR PRO LEU GLY VAL PRO ARG GLN SER GLY          
SEQRES  59 C 1214  ARG PRO GLY CYS CYS GLY GLY ARG CYS GLY GLY ARG ARG          
SEQRES  60 C 1214  CYS LEU ARG ARG TRP PHE HIS PHE TRP GLY ALA PRO VAL          
SEQRES  61 C 1214  THR ILE PHE MET GLY ASN VAL VAL SER TYR LEU LEU PHE          
SEQRES  62 C 1214  LEU LEU LEU PHE SER ARG VAL LEU LEU VAL ASP PHE GLN          
SEQRES  63 C 1214  PRO ALA PRO PRO GLY SER LEU GLU LEU LEU LEU TYR PHE          
SEQRES  64 C 1214  TRP ALA PHE THR LEU LEU CYS GLU GLU LEU ARG GLN GLY          
SEQRES  65 C 1214  LEU SER GLY GLY GLY GLY SER LEU ALA SER GLY GLY PRO          
SEQRES  66 C 1214  GLY PRO GLY HIS ALA SER LEU SER GLN ARG LEU ARG LEU          
SEQRES  67 C 1214  TYR LEU ALA ASP SER TRP ASN GLN CYS ASP LEU VAL ALA          
SEQRES  68 C 1214  LEU THR CYS PHE LEU LEU GLY VAL GLY CYS ARG LEU THR          
SEQRES  69 C 1214  PRO GLY LEU TYR HIS LEU GLY ARG THR VAL LEU CYS ILE          
SEQRES  70 C 1214  ASP PHE MET VAL PHE THR VAL ARG LEU LEU HIS ILE PHE          
SEQRES  71 C 1214  THR VAL ASN LYS GLN LEU GLY PRO LYS ILE VAL ILE VAL          
SEQRES  72 C 1214  SER LYS MET MET LYS ASP VAL PHE PHE PHE LEU PHE PHE          
SEQRES  73 C 1214  LEU GLY VAL TRP LEU VAL ALA TYR GLY VAL ALA THR GLU          
SEQRES  74 C 1214  GLY LEU LEU ARG PRO ARG ASP SER ASP PHE PRO SER ILE          
SEQRES  75 C 1214  LEU ARG ARG VAL PHE TYR ARG PRO TYR LEU GLN ILE PHE          
SEQRES  76 C 1214  GLY GLN ILE PRO GLN GLU ASP MET ASP VAL ALA LEU MET          
SEQRES  77 C 1214  GLU HIS SER ASN CYS SER SER GLU PRO GLY PHE TRP ALA          
SEQRES  78 C 1214  HIS PRO PRO GLY ALA GLN ALA GLY THR CYS VAL SER GLN          
SEQRES  79 C 1214  TYR ALA ASN TRP LEU VAL VAL LEU LEU LEU VAL ILE PHE          
SEQRES  80 C 1214  LEU LEU VAL ALA ASN ILE LEU LEU VAL ASN LEU LEU ILE          
SEQRES  81 C 1214  ALA MET PHE SER TYR THR PHE GLY LYS VAL GLN GLY ASN          
SEQRES  82 C 1214  SER ASP LEU TYR TRP LYS ALA GLN ARG TYR ARG LEU ILE          
SEQRES  83 C 1214  ARG GLU PHE HIS SER ARG PRO ALA LEU ALA PRO PRO PHE          
SEQRES  84 C 1214  ILE VAL ILE SER HIS LEU ARG LEU LEU LEU ARG GLN LEU          
SEQRES  85 C 1214  CYS ARG ARG PRO ARG SER PRO GLN PRO SER SER PRO ALA          
SEQRES  86 C 1214  LEU GLU HIS PHE ARG VAL TYR LEU SER LYS GLU ALA GLU          
SEQRES  87 C 1214  ARG LYS LEU LEU THR TRP GLU SER VAL HIS LYS GLU ASN          
SEQRES  88 C 1214  PHE LEU LEU ALA ARG ALA ARG ASP LYS ARG GLU SER ASP          
SEQRES  89 C 1214  SER GLU ARG LEU LYS ARG THR SER GLN LYS VAL ASP LEU          
SEQRES  90 C 1214  ALA LEU LYS GLN LEU GLY HIS ILE ARG GLU TYR GLU GLN          
SEQRES  91 C 1214  ARG LEU LYS VAL LEU GLU ARG GLU VAL GLN GLN CYS SER          
SEQRES  92 C 1214  ARG VAL LEU GLY TRP VAL ALA GLU ALA LEU SER ARG SER          
SEQRES  93 C 1214  ALA LEU LEU PRO PRO GLY GLY PRO PRO PRO PRO ASP LEU          
SEQRES  94 C 1214  PRO GLY SER LYS ASP                                          
SEQRES   1 D 1214  MET VAL VAL PRO GLU LYS GLU GLN SER TRP ILE PRO LYS          
SEQRES   2 D 1214  ILE PHE LYS LYS LYS THR CYS THR THR PHE ILE VAL ASP          
SEQRES   3 D 1214  SER THR ASP PRO GLY GLY THR LEU CYS GLN CYS GLY ARG          
SEQRES   4 D 1214  PRO ARG THR ALA HIS PRO ALA VAL ALA MET GLU ASP ALA          
SEQRES   5 D 1214  PHE GLY ALA ALA VAL VAL THR VAL TRP ASP SER ASP ALA          
SEQRES   6 D 1214  HIS THR THR GLU LYS PRO THR ASP ALA TYR GLY GLU LEU          
SEQRES   7 D 1214  ASP PHE THR GLY ALA GLY ARG LYS HIS SER ASN PHE LEU          
SEQRES   8 D 1214  ARG LEU SER ASP ARG THR ASP PRO ALA ALA VAL TYR SER          
SEQRES   9 D 1214  LEU VAL THR ARG THR TRP GLY PHE ARG ALA PRO ASN LEU          
SEQRES  10 D 1214  VAL VAL SER VAL LEU GLY GLY SER GLY GLY PRO VAL LEU          
SEQRES  11 D 1214  GLN THR TRP LEU GLN ASP LEU LEU ARG ARG GLY LEU VAL          
SEQRES  12 D 1214  ARG ALA ALA GLN SER THR GLY ALA TRP ILE VAL THR GLY          
SEQRES  13 D 1214  GLY LEU HIS THR GLY ILE GLY ARG HIS VAL GLY VAL ALA          
SEQRES  14 D 1214  VAL ARG ASP HIS GLN MET ALA SER THR GLY GLY THR LYS          
SEQRES  15 D 1214  VAL VAL ALA MET GLY VAL ALA PRO TRP GLY VAL VAL ARG          
SEQRES  16 D 1214  ASN ARG ASP THR LEU ILE ASN PRO LYS GLY SER PHE PRO          
SEQRES  17 D 1214  ALA ARG TYR ARG TRP ARG GLY ASP PRO GLU ASP GLY VAL          
SEQRES  18 D 1214  GLN PHE PRO LEU ASP TYR ASN TYR SER ALA PHE PHE LEU          
SEQRES  19 D 1214  VAL ASP ASP GLY THR HIS GLY CYS LEU GLY GLY GLU ASN          
SEQRES  20 D 1214  ARG PHE ARG LEU ARG LEU GLU SER TYR ILE SER GLN GLN          
SEQRES  21 D 1214  LYS THR GLY VAL GLY GLY THR GLY ILE ASP ILE PRO VAL          
SEQRES  22 D 1214  LEU LEU LEU LEU ILE ASP GLY ASP GLU LYS MET LEU THR          
SEQRES  23 D 1214  ARG ILE GLU ASN ALA THR GLN ALA GLN LEU PRO CYS LEU          
SEQRES  24 D 1214  LEU VAL ALA GLY SER GLY GLY ALA ALA ASP CYS LEU ALA          
SEQRES  25 D 1214  GLU THR LEU GLU ASP THR LEU ALA PRO GLY SER GLY GLY          
SEQRES  26 D 1214  ALA ARG GLN GLY GLU ALA ARG ASP ARG ILE ARG ARG PHE          
SEQRES  27 D 1214  PHE PRO LYS GLY ASP LEU GLU VAL LEU GLN ALA GLN VAL          
SEQRES  28 D 1214  GLU ARG ILE MET THR ARG LYS GLU LEU LEU THR VAL TYR          
SEQRES  29 D 1214  SER SER GLU ASP GLY SER GLU GLU PHE GLU THR ILE VAL          
SEQRES  30 D 1214  LEU LYS ALA LEU VAL LYS ALA CYS GLY SER SER GLU ALA          
SEQRES  31 D 1214  SER ALA TYR LEU ASP GLU LEU ARG LEU ALA VAL ALA TRP          
SEQRES  32 D 1214  ASN ARG VAL ASP ILE ALA GLN SER GLU LEU PHE ARG GLY          
SEQRES  33 D 1214  ASP ILE GLN TRP ARG SER PHE HIS LEU GLU ALA SER LEU          
SEQRES  34 D 1214  MET ASP ALA LEU LEU ASN ASP ARG PRO GLU PHE VAL ARG          
SEQRES  35 D 1214  LEU LEU ILE SER HIS GLY LEU SER LEU GLY HIS PHE LEU          
SEQRES  36 D 1214  THR PRO MET ARG LEU ALA GLN LEU TYR SER ALA ALA PRO          
SEQRES  37 D 1214  SER ASN SER LEU ILE ARG ASN LEU LEU ASP GLN ALA SER          
SEQRES  38 D 1214  HIS SER ALA GLY THR LYS ALA PRO ALA LEU LYS GLY GLY          
SEQRES  39 D 1214  ALA ALA GLU LEU ARG PRO PRO ASP VAL GLY HIS VAL LEU          
SEQRES  40 D 1214  ARG MET LEU LEU GLY LYS MET CYS ALA PRO ARG TYR PRO          
SEQRES  41 D 1214  SER GLY GLY ALA TRP ASP PRO HIS PRO GLY GLN GLY PHE          
SEQRES  42 D 1214  GLY GLU SER MET TYR LEU LEU SER ASP LYS ALA THR SER          
SEQRES  43 D 1214  PRO LEU SER LEU ASP ALA GLY LEU GLY GLN ALA PRO TRP          
SEQRES  44 D 1214  SER ASP LEU LEU LEU TRP ALA LEU LEU LEU ASN ARG ALA          
SEQRES  45 D 1214  GLN MET ALA MET TYR PHE TRP GLU MET GLY SER ASN ALA          
SEQRES  46 D 1214  VAL SER SER ALA LEU GLY ALA CYS LEU LEU LEU ARG VAL          
SEQRES  47 D 1214  MET ALA ARG LEU GLU PRO ASP ALA GLU GLU ALA ALA ARG          
SEQRES  48 D 1214  ARG LYS ASP LEU ALA PHE LYS PHE GLU GLY MET GLY VAL          
SEQRES  49 D 1214  ASP LEU PHE GLY GLU CYS TYR ARG SER SER GLU VAL ARG          
SEQRES  50 D 1214  ALA ALA ARG LEU LEU LEU ARG ARG CYS PRO LEU TRP GLY          
SEQRES  51 D 1214  ASP ALA THR CYS LEU GLN LEU ALA MET GLN ALA ASP ALA          
SEQRES  52 D 1214  ARG ALA PHE PHE ALA GLN ASP GLY VAL GLN SER LEU LEU          
SEQRES  53 D 1214  THR GLN LYS TRP TRP GLY ASP MET ALA SER THR THR PRO          
SEQRES  54 D 1214  ILE TRP ALA LEU VAL LEU ALA PHE PHE CYS PRO PRO LEU          
SEQRES  55 D 1214  ILE TYR THR ARG LEU ILE THR PHE ARG LYS SER GLU GLU          
SEQRES  56 D 1214  GLU PRO THR ARG GLU GLU LEU GLU PHE ASP MET ASP SER          
SEQRES  57 D 1214  VAL ILE ASN GLY GLU GLY PRO VAL GLY THR ALA ASP PRO          
SEQRES  58 D 1214  ALA GLU LYS THR PRO LEU GLY VAL PRO ARG GLN SER GLY          
SEQRES  59 D 1214  ARG PRO GLY CYS CYS GLY GLY ARG CYS GLY GLY ARG ARG          
SEQRES  60 D 1214  CYS LEU ARG ARG TRP PHE HIS PHE TRP GLY ALA PRO VAL          
SEQRES  61 D 1214  THR ILE PHE MET GLY ASN VAL VAL SER TYR LEU LEU PHE          
SEQRES  62 D 1214  LEU LEU LEU PHE SER ARG VAL LEU LEU VAL ASP PHE GLN          
SEQRES  63 D 1214  PRO ALA PRO PRO GLY SER LEU GLU LEU LEU LEU TYR PHE          
SEQRES  64 D 1214  TRP ALA PHE THR LEU LEU CYS GLU GLU LEU ARG GLN GLY          
SEQRES  65 D 1214  LEU SER GLY GLY GLY GLY SER LEU ALA SER GLY GLY PRO          
SEQRES  66 D 1214  GLY PRO GLY HIS ALA SER LEU SER GLN ARG LEU ARG LEU          
SEQRES  67 D 1214  TYR LEU ALA ASP SER TRP ASN GLN CYS ASP LEU VAL ALA          
SEQRES  68 D 1214  LEU THR CYS PHE LEU LEU GLY VAL GLY CYS ARG LEU THR          
SEQRES  69 D 1214  PRO GLY LEU TYR HIS LEU GLY ARG THR VAL LEU CYS ILE          
SEQRES  70 D 1214  ASP PHE MET VAL PHE THR VAL ARG LEU LEU HIS ILE PHE          
SEQRES  71 D 1214  THR VAL ASN LYS GLN LEU GLY PRO LYS ILE VAL ILE VAL          
SEQRES  72 D 1214  SER LYS MET MET LYS ASP VAL PHE PHE PHE LEU PHE PHE          
SEQRES  73 D 1214  LEU GLY VAL TRP LEU VAL ALA TYR GLY VAL ALA THR GLU          
SEQRES  74 D 1214  GLY LEU LEU ARG PRO ARG ASP SER ASP PHE PRO SER ILE          
SEQRES  75 D 1214  LEU ARG ARG VAL PHE TYR ARG PRO TYR LEU GLN ILE PHE          
SEQRES  76 D 1214  GLY GLN ILE PRO GLN GLU ASP MET ASP VAL ALA LEU MET          
SEQRES  77 D 1214  GLU HIS SER ASN CYS SER SER GLU PRO GLY PHE TRP ALA          
SEQRES  78 D 1214  HIS PRO PRO GLY ALA GLN ALA GLY THR CYS VAL SER GLN          
SEQRES  79 D 1214  TYR ALA ASN TRP LEU VAL VAL LEU LEU LEU VAL ILE PHE          
SEQRES  80 D 1214  LEU LEU VAL ALA ASN ILE LEU LEU VAL ASN LEU LEU ILE          
SEQRES  81 D 1214  ALA MET PHE SER TYR THR PHE GLY LYS VAL GLN GLY ASN          
SEQRES  82 D 1214  SER ASP LEU TYR TRP LYS ALA GLN ARG TYR ARG LEU ILE          
SEQRES  83 D 1214  ARG GLU PHE HIS SER ARG PRO ALA LEU ALA PRO PRO PHE          
SEQRES  84 D 1214  ILE VAL ILE SER HIS LEU ARG LEU LEU LEU ARG GLN LEU          
SEQRES  85 D 1214  CYS ARG ARG PRO ARG SER PRO GLN PRO SER SER PRO ALA          
SEQRES  86 D 1214  LEU GLU HIS PHE ARG VAL TYR LEU SER LYS GLU ALA GLU          
SEQRES  87 D 1214  ARG LYS LEU LEU THR TRP GLU SER VAL HIS LYS GLU ASN          
SEQRES  88 D 1214  PHE LEU LEU ALA ARG ALA ARG ASP LYS ARG GLU SER ASP          
SEQRES  89 D 1214  SER GLU ARG LEU LYS ARG THR SER GLN LYS VAL ASP LEU          
SEQRES  90 D 1214  ALA LEU LYS GLN LEU GLY HIS ILE ARG GLU TYR GLU GLN          
SEQRES  91 D 1214  ARG LEU LYS VAL LEU GLU ARG GLU VAL GLN GLN CYS SER          
SEQRES  92 D 1214  ARG VAL LEU GLY TRP VAL ALA GLU ALA LEU SER ARG SER          
SEQRES  93 D 1214  ALA LEU LEU PRO PRO GLY GLY PRO PRO PRO PRO ASP LEU          
SEQRES  94 D 1214  PRO GLY SER LYS ASP                                          
HET    DVT  A2001      38                                                       
HET    DVT  A2002      38                                                       
HET    DVT  B2001      38                                                       
HET    DVT  B2002      38                                                       
HET    DVT  C2001      38                                                       
HET    DVT  C2002      38                                                       
HET    DVT  D2001      38                                                       
HET    DVT  D2002      38                                                       
HETNAM     DVT DECAVANADATE                                                     
FORMUL   5  DVT    8(O28 V10 6-)                                                
HELIX    1 AA1 TRP A   10  PHE A   15  1                                   6    
HELIX    2 AA2 ASP A   98  THR A  109  1                                  12    
HELIX    3 AA3 GLN A  131  THR A  149  1                                  19    
HELIX    4 AA4 ILE A  162  SER A  177  1                                  16    
HELIX    5 AA5 ASN A  247  SER A  258  1                                  12    
HELIX    6 AA6 LYS A  283  GLN A  295  1                                  13    
HELIX    7 AA7 ALA A  308  GLU A  316  1                                   9    
HELIX    8 AA8 GLN A  328  ASP A  333  1                                   6    
HELIX    9 AA9 GLN A  348  ARG A  353  1                                   6    
HELIX   10 AB1 GLU A  372  ALA A  384  1                                  13    
HELIX   11 AB2 ASP A  395  TRP A  403  1                                   9    
HELIX   12 AB3 VAL A  406  ARG A  415  1                                  10    
HELIX   13 AB4 SER A  422  ASN A  435  1                                  14    
HELIX   14 AB5 ARG A  437  HIS A  447  1                                  11    
HELIX   15 AB6 SER A  450  LEU A  455  1                                   6    
HELIX   16 AB7 THR A  456  ALA A  466  1                                  11    
HELIX   17 AB8 LEU A  472  GLN A  479  1                                   8    
HELIX   18 AB9 TRP A  559  LEU A  569  1                                  11    
HELIX   19 AC1 ARG A  571  MET A  581  1                                  11    
HELIX   20 AC2 ASN A  584  ALA A  600  1                                  17    
HELIX   21 AC3 GLU A  608  ARG A  632  1                                  25    
HELIX   22 AC4 SER A  634  ARG A  644  1                                  11    
HELIX   23 AC5 PRO A  647  GLY A  650  5                                   4    
HELIX   24 AC6 CYS A  654  GLN A  660  1                                   7    
HELIX   25 AC7 ALA A  663  GLN A  669  1                                   7    
HELIX   26 AC8 GLN A  669  TRP A  681  1                                  13    
HELIX   27 AC9 PRO A  689  CYS A  699  1                                  11    
HELIX   28 AD1 PRO A  700  ILE A  703  5                                   4    
HELIX   29 AD2 ARG A  767  TRP A  776  1                                  10    
HELIX   30 AD3 ALA A  778  VAL A  803  1                                  26    
HELIX   31 AD4 GLY A  811  GLY A  835  1                                  25    
HELIX   32 AD5 SER A  851  LEU A  860  1                                  10    
HELIX   33 AD6 ASP A  862  THR A  884  1                                  23    
HELIX   34 AD7 LEU A  887  ARG A  905  1                                  19    
HELIX   35 AD8 LEU A  906  VAL A  912  5                                   7    
HELIX   36 AD9 LEU A  916  LYS A  925  1                                  10    
HELIX   37 AE1 ASP A  929  ARG A  953  1                                  25    
HELIX   38 AE2 ASP A  958  LEU A  972  1                                  15    
HELIX   39 AE3 ASN A 1017  LEU A 1034  1                                  18    
HELIX   40 AE4 LEU A 1034  GLN A 1061  1                                  28    
HELIX   41 AE5 GLN A 1061  ARG A 1072  1                                  12    
HELIX   42 AE6 PHE A 1079  LEU A 1088  1                                  10    
HELIX   43 AE7 SER A 1114  GLU A 1142  1                                  29    
HELIX   44 AE8 GLU A 1146  GLY A 1163  1                                  18    
HELIX   45 AE9 ILE A 1165  ALA A 1192  1                                  28    
HELIX   46 AF1 TRP B   10  PHE B   15  1                                   6    
HELIX   47 AF2 ASP B   98  THR B  109  1                                  12    
HELIX   48 AF3 GLN B  131  THR B  149  1                                  19    
HELIX   49 AF4 ILE B  162  SER B  177  1                                  16    
HELIX   50 AF5 ASN B  247  SER B  258  1                                  12    
HELIX   51 AF6 LYS B  283  GLN B  295  1                                  13    
HELIX   52 AF7 ALA B  308  GLU B  316  1                                   9    
HELIX   53 AF8 GLN B  328  ASP B  333  1                                   6    
HELIX   54 AF9 GLN B  348  ARG B  353  1                                   6    
HELIX   55 AG1 GLU B  372  ALA B  384  1                                  13    
HELIX   56 AG2 ASP B  395  TRP B  403  1                                   9    
HELIX   57 AG3 VAL B  406  ARG B  415  1                                  10    
HELIX   58 AG4 SER B  422  ASN B  435  1                                  14    
HELIX   59 AG5 ARG B  437  HIS B  447  1                                  11    
HELIX   60 AG6 SER B  450  LEU B  455  1                                   6    
HELIX   61 AG7 THR B  456  ALA B  466  1                                  11    
HELIX   62 AG8 LEU B  472  GLN B  479  1                                   8    
HELIX   63 AG9 TRP B  559  LEU B  569  1                                  11    
HELIX   64 AH1 ARG B  571  MET B  581  1                                  11    
HELIX   65 AH2 ASN B  584  ALA B  600  1                                  17    
HELIX   66 AH3 GLU B  608  ARG B  632  1                                  25    
HELIX   67 AH4 SER B  634  ARG B  644  1                                  11    
HELIX   68 AH5 PRO B  647  GLY B  650  5                                   4    
HELIX   69 AH6 CYS B  654  GLN B  660  1                                   7    
HELIX   70 AH7 ALA B  663  GLN B  669  1                                   7    
HELIX   71 AH8 GLN B  669  TRP B  681  1                                  13    
HELIX   72 AH9 PRO B  689  CYS B  699  1                                  11    
HELIX   73 AI1 PRO B  700  ILE B  703  5                                   4    
HELIX   74 AI2 ARG B  767  TRP B  776  1                                  10    
HELIX   75 AI3 ALA B  778  VAL B  803  1                                  26    
HELIX   76 AI4 GLY B  811  GLY B  835  1                                  25    
HELIX   77 AI5 SER B  851  LEU B  860  1                                  10    
HELIX   78 AI6 ASP B  862  THR B  884  1                                  23    
HELIX   79 AI7 LEU B  887  ARG B  905  1                                  19    
HELIX   80 AI8 LEU B  906  VAL B  912  5                                   7    
HELIX   81 AI9 LEU B  916  LYS B  925  1                                  10    
HELIX   82 AJ1 ASP B  929  ARG B  953  1                                  25    
HELIX   83 AJ2 ASP B  958  LEU B  972  1                                  15    
HELIX   84 AJ3 ASN B 1017  LEU B 1034  1                                  18    
HELIX   85 AJ4 LEU B 1034  GLN B 1061  1                                  28    
HELIX   86 AJ5 GLN B 1061  ARG B 1072  1                                  12    
HELIX   87 AJ6 PHE B 1079  LEU B 1088  1                                  10    
HELIX   88 AJ7 SER B 1114  GLU B 1142  1                                  29    
HELIX   89 AJ8 GLU B 1146  GLY B 1163  1                                  18    
HELIX   90 AJ9 ILE B 1165  ALA B 1192  1                                  28    
HELIX   91 AK1 TRP C   10  PHE C   15  1                                   6    
HELIX   92 AK2 ASP C   98  THR C  109  1                                  12    
HELIX   93 AK3 GLN C  131  THR C  149  1                                  19    
HELIX   94 AK4 ILE C  162  SER C  177  1                                  16    
HELIX   95 AK5 ASN C  247  SER C  258  1                                  12    
HELIX   96 AK6 LYS C  283  GLN C  295  1                                  13    
HELIX   97 AK7 ALA C  308  GLU C  316  1                                   9    
HELIX   98 AK8 GLN C  328  ASP C  333  1                                   6    
HELIX   99 AK9 GLN C  348  ARG C  353  1                                   6    
HELIX  100 AL1 GLU C  372  ALA C  384  1                                  13    
HELIX  101 AL2 ASP C  395  TRP C  403  1                                   9    
HELIX  102 AL3 VAL C  406  ARG C  415  1                                  10    
HELIX  103 AL4 SER C  422  ASN C  435  1                                  14    
HELIX  104 AL5 ARG C  437  HIS C  447  1                                  11    
HELIX  105 AL6 SER C  450  LEU C  455  1                                   6    
HELIX  106 AL7 THR C  456  ALA C  466  1                                  11    
HELIX  107 AL8 LEU C  472  GLN C  479  1                                   8    
HELIX  108 AL9 TRP C  559  LEU C  569  1                                  11    
HELIX  109 AM1 ARG C  571  MET C  581  1                                  11    
HELIX  110 AM2 ASN C  584  ALA C  600  1                                  17    
HELIX  111 AM3 GLU C  608  ARG C  632  1                                  25    
HELIX  112 AM4 SER C  634  ARG C  644  1                                  11    
HELIX  113 AM5 PRO C  647  GLY C  650  5                                   4    
HELIX  114 AM6 CYS C  654  GLN C  660  1                                   7    
HELIX  115 AM7 ALA C  663  GLN C  669  1                                   7    
HELIX  116 AM8 GLN C  669  TRP C  681  1                                  13    
HELIX  117 AM9 PRO C  689  CYS C  699  1                                  11    
HELIX  118 AN1 PRO C  700  ILE C  703  5                                   4    
HELIX  119 AN2 ARG C  767  TRP C  776  1                                  10    
HELIX  120 AN3 ALA C  778  VAL C  803  1                                  26    
HELIX  121 AN4 GLY C  811  GLY C  835  1                                  25    
HELIX  122 AN5 SER C  851  LEU C  860  1                                  10    
HELIX  123 AN6 ASP C  862  THR C  884  1                                  23    
HELIX  124 AN7 LEU C  887  ARG C  905  1                                  19    
HELIX  125 AN8 LEU C  906  VAL C  912  5                                   7    
HELIX  126 AN9 LEU C  916  LYS C  925  1                                  10    
HELIX  127 AO1 ASP C  929  ARG C  953  1                                  25    
HELIX  128 AO2 ASP C  958  LEU C  972  1                                  15    
HELIX  129 AO3 ASN C 1017  LEU C 1034  1                                  18    
HELIX  130 AO4 LEU C 1034  GLN C 1061  1                                  28    
HELIX  131 AO5 GLN C 1061  ARG C 1072  1                                  12    
HELIX  132 AO6 PHE C 1079  LEU C 1088  1                                  10    
HELIX  133 AO7 SER C 1114  GLU C 1142  1                                  29    
HELIX  134 AO8 GLU C 1146  GLY C 1163  1                                  18    
HELIX  135 AO9 ILE C 1165  ALA C 1192  1                                  28    
HELIX  136 AP1 TRP D   10  PHE D   15  1                                   6    
HELIX  137 AP2 ASP D   98  THR D  109  1                                  12    
HELIX  138 AP3 GLN D  131  THR D  149  1                                  19    
HELIX  139 AP4 ILE D  162  SER D  177  1                                  16    
HELIX  140 AP5 ASN D  247  SER D  258  1                                  12    
HELIX  141 AP6 LYS D  283  GLN D  295  1                                  13    
HELIX  142 AP7 ALA D  308  GLU D  316  1                                   9    
HELIX  143 AP8 GLN D  328  ASP D  333  1                                   6    
HELIX  144 AP9 GLN D  348  ARG D  353  1                                   6    
HELIX  145 AQ1 GLU D  372  ALA D  384  1                                  13    
HELIX  146 AQ2 ASP D  395  TRP D  403  1                                   9    
HELIX  147 AQ3 VAL D  406  ARG D  415  1                                  10    
HELIX  148 AQ4 SER D  422  ASN D  435  1                                  14    
HELIX  149 AQ5 ARG D  437  HIS D  447  1                                  11    
HELIX  150 AQ6 SER D  450  LEU D  455  1                                   6    
HELIX  151 AQ7 THR D  456  ALA D  466  1                                  11    
HELIX  152 AQ8 LEU D  472  GLN D  479  1                                   8    
HELIX  153 AQ9 TRP D  559  LEU D  569  1                                  11    
HELIX  154 AR1 ARG D  571  MET D  581  1                                  11    
HELIX  155 AR2 ASN D  584  ALA D  600  1                                  17    
HELIX  156 AR3 GLU D  608  ARG D  632  1                                  25    
HELIX  157 AR4 SER D  634  ARG D  644  1                                  11    
HELIX  158 AR5 PRO D  647  GLY D  650  5                                   4    
HELIX  159 AR6 CYS D  654  GLN D  660  1                                   7    
HELIX  160 AR7 ALA D  663  GLN D  669  1                                   7    
HELIX  161 AR8 GLN D  669  TRP D  681  1                                  13    
HELIX  162 AR9 PRO D  689  CYS D  699  1                                  11    
HELIX  163 AS1 PRO D  700  ILE D  703  5                                   4    
HELIX  164 AS2 ARG D  767  TRP D  776  1                                  10    
HELIX  165 AS3 ALA D  778  VAL D  803  1                                  26    
HELIX  166 AS4 GLY D  811  GLY D  835  1                                  25    
HELIX  167 AS5 SER D  851  LEU D  860  1                                  10    
HELIX  168 AS6 ASP D  862  THR D  884  1                                  23    
HELIX  169 AS7 LEU D  887  ARG D  905  1                                  19    
HELIX  170 AS8 LEU D  906  VAL D  912  5                                   7    
HELIX  171 AS9 LEU D  916  LYS D  925  1                                  10    
HELIX  172 AT1 ASP D  929  ARG D  953  1                                  25    
HELIX  173 AT2 ASP D  958  LEU D  972  1                                  15    
HELIX  174 AT3 ASN D 1017  LEU D 1034  1                                  18    
HELIX  175 AT4 LEU D 1034  GLN D 1061  1                                  28    
HELIX  176 AT5 GLN D 1061  ARG D 1072  1                                  12    
HELIX  177 AT6 PHE D 1079  LEU D 1088  1                                  10    
HELIX  178 AT7 SER D 1114  GLU D 1142  1                                  29    
HELIX  179 AT8 GLU D 1146  GLY D 1163  1                                  18    
HELIX  180 AT9 ILE D 1165  ALA D 1192  1                                  28    
SHEET    1 AA1 2 LYS A  16  LYS A  17  0                                        
SHEET    2 AA1 2 LYS A  70  PRO A  71 -1  O  LYS A  70   N  LYS A  17           
SHEET    1 AA2 8 TYR A  75  LEU A  78  0                                        
SHEET    2 AA2 8 SER A  88  SER A  94 -1  O  SER A  88   N  LEU A  78           
SHEET    3 AA2 8 ALA A 231  ASP A 236  1  O  LEU A 234   N  LEU A  91           
SHEET    4 AA2 8 MET A 186  PRO A 190  1  N  GLY A 187   O  PHE A 233           
SHEET    5 AA2 8 ALA A 151  GLY A 156  1  N  ILE A 153   O  MET A 186           
SHEET    6 AA2 8 LEU A 117  VAL A 121  1  N  LEU A 117   O  TRP A 152           
SHEET    7 AA2 8 VAL A 273  LEU A 277  1  O  LEU A 274   N  VAL A 118           
SHEET    8 AA2 8 CYS A 298  VAL A 301  1  O  LEU A 300   N  LEU A 277           
SHEET    1 AA3 2 ARG A 645  CYS A 646  0                                        
SHEET    2 AA3 2 ALA A 652  THR A 653 -1  O  ALA A 652   N  CYS A 646           
SHEET    1 AA4 2 TRP A1000  ALA A1001  0                                        
SHEET    2 AA4 2 VAL A1012  SER A1013 -1  O  VAL A1012   N  ALA A1001           
SHEET    1 AA5 2 LYS B  16  LYS B  17  0                                        
SHEET    2 AA5 2 LYS B  70  PRO B  71 -1  O  LYS B  70   N  LYS B  17           
SHEET    1 AA6 8 TYR B  75  LEU B  78  0                                        
SHEET    2 AA6 8 SER B  88  SER B  94 -1  O  SER B  88   N  LEU B  78           
SHEET    3 AA6 8 ALA B 231  ASP B 236  1  O  LEU B 234   N  LEU B  91           
SHEET    4 AA6 8 MET B 186  PRO B 190  1  N  GLY B 187   O  PHE B 233           
SHEET    5 AA6 8 ALA B 151  GLY B 156  1  N  ILE B 153   O  MET B 186           
SHEET    6 AA6 8 LEU B 117  VAL B 121  1  N  LEU B 117   O  TRP B 152           
SHEET    7 AA6 8 VAL B 273  LEU B 277  1  O  LEU B 274   N  VAL B 118           
SHEET    8 AA6 8 CYS B 298  VAL B 301  1  O  LEU B 300   N  LEU B 277           
SHEET    1 AA7 2 ARG B 645  CYS B 646  0                                        
SHEET    2 AA7 2 ALA B 652  THR B 653 -1  O  ALA B 652   N  CYS B 646           
SHEET    1 AA8 2 TRP B1000  ALA B1001  0                                        
SHEET    2 AA8 2 VAL B1012  SER B1013 -1  O  VAL B1012   N  ALA B1001           
SHEET    1 AA9 2 LYS C  16  LYS C  17  0                                        
SHEET    2 AA9 2 LYS C  70  PRO C  71 -1  O  LYS C  70   N  LYS C  17           
SHEET    1 AB1 8 TYR C  75  LEU C  78  0                                        
SHEET    2 AB1 8 SER C  88  SER C  94 -1  O  SER C  88   N  LEU C  78           
SHEET    3 AB1 8 ALA C 231  ASP C 236  1  O  LEU C 234   N  LEU C  91           
SHEET    4 AB1 8 MET C 186  PRO C 190  1  N  GLY C 187   O  PHE C 233           
SHEET    5 AB1 8 ALA C 151  GLY C 156  1  N  ILE C 153   O  MET C 186           
SHEET    6 AB1 8 LEU C 117  VAL C 121  1  N  LEU C 117   O  TRP C 152           
SHEET    7 AB1 8 VAL C 273  LEU C 277  1  O  LEU C 274   N  VAL C 118           
SHEET    8 AB1 8 CYS C 298  VAL C 301  1  O  LEU C 300   N  LEU C 277           
SHEET    1 AB2 2 ARG C 645  CYS C 646  0                                        
SHEET    2 AB2 2 ALA C 652  THR C 653 -1  O  ALA C 652   N  CYS C 646           
SHEET    1 AB3 2 TRP C1000  ALA C1001  0                                        
SHEET    2 AB3 2 VAL C1012  SER C1013 -1  O  VAL C1012   N  ALA C1001           
SHEET    1 AB4 2 LYS D  16  LYS D  17  0                                        
SHEET    2 AB4 2 LYS D  70  PRO D  71 -1  O  LYS D  70   N  LYS D  17           
SHEET    1 AB5 8 TYR D  75  LEU D  78  0                                        
SHEET    2 AB5 8 SER D  88  SER D  94 -1  O  SER D  88   N  LEU D  78           
SHEET    3 AB5 8 ALA D 231  ASP D 236  1  O  LEU D 234   N  LEU D  91           
SHEET    4 AB5 8 MET D 186  PRO D 190  1  N  GLY D 187   O  PHE D 233           
SHEET    5 AB5 8 ALA D 151  GLY D 156  1  N  ILE D 153   O  MET D 186           
SHEET    6 AB5 8 LEU D 117  VAL D 121  1  N  LEU D 117   O  TRP D 152           
SHEET    7 AB5 8 VAL D 273  LEU D 277  1  O  LEU D 274   N  VAL D 118           
SHEET    8 AB5 8 CYS D 298  VAL D 301  1  O  LEU D 300   N  LEU D 277           
SHEET    1 AB6 2 ARG D 645  CYS D 646  0                                        
SHEET    2 AB6 2 ALA D 652  THR D 653 -1  O  ALA D 652   N  CYS D 646           
SHEET    1 AB7 2 TRP D1000  ALA D1001  0                                        
SHEET    2 AB7 2 VAL D1012  SER D1013 -1  O  VAL D1012   N  ALA D1001           
SITE     1 AC1  5 ARG A1138  ARG A1141  ARG A1147  LYS A1154                    
SITE     2 AC1  5 LYS D1149                                                     
SITE     1 AC2  4 ARG A 421  PHE A 423  THR D 160  ARG D 214                    
SITE     1 AC3  5 LYS A1149  ARG B1138  ARG B1141  ARG B1147                    
SITE     2 AC3  5 LYS B1154                                                     
SITE     1 AC4  4 THR A 160  ARG A 214  ARG B 421  PHE B 423                    
SITE     1 AC5  5 LYS B1149  ARG C1138  ARG C1141  ARG C1147                    
SITE     2 AC5  5 LYS C1154                                                     
SITE     1 AC6  4 THR B 160  ARG B 214  ARG C 421  PHE C 423                    
SITE     1 AC7  5 LYS C1149  ARG D1138  ARG D1141  ARG D1147                    
SITE     2 AC7  5 LYS D1154                                                     
SITE     1 AC8  4 THR C 160  ARG C 214  ARG D 421  PHE D 423                    
CRYST1    1.000    1.000    1.000  90.00  90.00  90.00 P 1                      
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      1.000000  0.000000  0.000000        0.00000                         
SCALE2      0.000000  1.000000  0.000000        0.00000                         
SCALE3      0.000000  0.000000  1.000000        0.00000                         
(ATOM LINES ARE NOT SHOWN.)
END                                                                             
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