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Database: PDB
Entry: 6AVR
LinkDB: 6AVR
Original site: 6AVR 
HEADER    SIGNALING PROTEIN                       04-SEP-17   6AVR              
TITLE     HUMAN ALPHA-V BETA-3 INTEGRIN (INTERMEDIATE CONFORMATION) IN COMPLEX  
TITLE    2 WITH THE THERAPEUTIC ANTIBODY LM609                                  
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: INTEGRIN ALPHA-V;                                          
COMPND   3 CHAIN: A;                                                            
COMPND   4 FRAGMENT: UNP RESIDUES 31-987;                                       
COMPND   5 SYNONYM: VITRONECTIN RECEPTOR,VITRONECTIN RECEPTOR SUBUNIT ALPHA;    
COMPND   6 ENGINEERED: YES;                                                     
COMPND   7 MOL_ID: 2;                                                           
COMPND   8 MOLECULE: INTEGRIN BETA-3;                                           
COMPND   9 CHAIN: B;                                                            
COMPND  10 FRAGMENT: UNP RESIDUES 27-718;                                       
COMPND  11 SYNONYM: PLATELET MEMBRANE GLYCOPROTEIN IIIA,GPIIIA;                 
COMPND  12 ENGINEERED: YES;                                                     
COMPND  13 MOL_ID: 3;                                                           
COMPND  14 MOLECULE: FAB LM609 HEAVY CHAIN;                                     
COMPND  15 CHAIN: H;                                                            
COMPND  16 ENGINEERED: YES;                                                     
COMPND  17 MOL_ID: 4;                                                           
COMPND  18 MOLECULE: FAB LM609 LIGHT CHAIN;                                     
COMPND  19 CHAIN: L;                                                            
COMPND  20 ENGINEERED: YES                                                      
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE   3 ORGANISM_COMMON: HUMAN;                                              
SOURCE   4 ORGANISM_TAXID: 9606;                                                
SOURCE   5 GENE: ITGAV, MSK8, VNRA, VTNR;                                       
SOURCE   6 EXPRESSION_SYSTEM: DROSOPHILA MELANOGASTER;                          
SOURCE   7 EXPRESSION_SYSTEM_TAXID: 7227;                                       
SOURCE   8 MOL_ID: 2;                                                           
SOURCE   9 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  10 ORGANISM_COMMON: HUMAN;                                              
SOURCE  11 ORGANISM_TAXID: 9606;                                                
SOURCE  12 GENE: ITGB3, GP3A;                                                   
SOURCE  13 EXPRESSION_SYSTEM: DROSOPHILA MELANOGASTER;                          
SOURCE  14 EXPRESSION_SYSTEM_TAXID: 7227;                                       
SOURCE  15 MOL_ID: 3;                                                           
SOURCE  16 ORGANISM_SCIENTIFIC: MUS MUSCULUS;                                   
SOURCE  17 ORGANISM_TAXID: 10090;                                               
SOURCE  18 EXPRESSION_SYSTEM: DROSOPHILA MELANOGASTER;                          
SOURCE  19 EXPRESSION_SYSTEM_TAXID: 7227;                                       
SOURCE  20 MOL_ID: 4;                                                           
SOURCE  21 ORGANISM_SCIENTIFIC: MUS MUSCULUS;                                   
SOURCE  22 ORGANISM_TAXID: 10090;                                               
SOURCE  23 EXPRESSION_SYSTEM: DROSOPHILA MELANOGASTER;                          
SOURCE  24 EXPRESSION_SYSTEM_TAXID: 7227                                        
KEYWDS    ALPHA-V BETA-3 INTEGRIN, LM609, VITAXIN, ABEGRIN, SIGNALING PROTEIN   
EXPDTA    ELECTRON MICROSCOPY                                                   
AUTHOR    A.J.BORST,Z.N.JAMES,W.N.ZAGOTTA,M.GINSBERG,F.A.REY,F.DIMAIO,          
AUTHOR   2 M.BACKOVIC,D.VEESLER                                                 
REVDAT   3   18-JUL-18 6AVR    1       REMARK                                   
REVDAT   2   15-NOV-17 6AVR    1       JRNL                                     
REVDAT   1   01-NOV-17 6AVR    0                                                
JRNL        AUTH   A.J.BORST,Z.M.JAMES,W.N.ZAGOTTA,M.GINSBERG,F.A.REY,F.DIMAIO, 
JRNL        AUTH 2 M.BACKOVIC,D.VEESLER                                         
JRNL        TITL   THE THERAPEUTIC ANTIBODY LM609 SELECTIVELY INHIBITS LIGAND   
JRNL        TITL 2 BINDING TO HUMAN ALPHA V BETA 3 INTEGRIN VIA STERIC          
JRNL        TITL 3 HINDRANCE.                                                   
JRNL        REF    STRUCTURE                     V.  25  1732 2017              
JRNL        REFN                   ISSN 1878-4186                               
JRNL        PMID   29033288                                                     
JRNL        DOI    10.1016/J.STR.2017.09.007                                    
REMARK   2                                                                      
REMARK   2 RESOLUTION.   35.00 ANGSTROMS.                                       
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   SOFTWARE PACKAGES      : UCSF CHIMERA, ROSETTA                     
REMARK   3   RECONSTRUCTION SCHEMA  : NULL                                      
REMARK   3                                                                      
REMARK   3 EM MAP-MODEL FITTING AND REFINEMENT                                  
REMARK   3   PDB ENTRY                    : NULL                                
REMARK   3   REFINEMENT SPACE             : REAL                                
REMARK   3   REFINEMENT PROTOCOL          : FLEXIBLE FIT                        
REMARK   3   REFINEMENT TARGET            : NULL                                
REMARK   3   OVERALL ANISOTROPIC B VALUE  : NULL                                
REMARK   3                                                                      
REMARK   3 FITTING PROCEDURE : NULL                                             
REMARK   3                                                                      
REMARK   3 EM IMAGE RECONSTRUCTION STATISTICS                                   
REMARK   3   NOMINAL PIXEL SIZE (ANGSTROMS)    : NULL                           
REMARK   3   ACTUAL PIXEL SIZE  (ANGSTROMS)    : NULL                           
REMARK   3   EFFECTIVE RESOLUTION (ANGSTROMS)  : 35.00                          
REMARK   3   NUMBER OF PARTICLES               : 650                            
REMARK   3   CTF CORRECTION METHOD             : NONE                           
REMARK   3                                                                      
REMARK   3 EM RECONSTRUCTION MAGNIFICATION CALIBRATION: NULL                    
REMARK   3                                                                      
REMARK   3 OTHER DETAILS: NULL                                                  
REMARK   4                                                                      
REMARK   4 6AVR COMPLIES WITH FORMAT V. 3.30, 13-JUL-11                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 08-SEP-17.                  
REMARK 100 THE DEPOSITION ID IS D_1000229908.                                   
REMARK 245                                                                      
REMARK 245 EXPERIMENTAL DETAILS                                                 
REMARK 245   RECONSTRUCTION METHOD          : SINGLE PARTICLE                   
REMARK 245   SPECIMEN TYPE                  : NULL                              
REMARK 245                                                                      
REMARK 245 ELECTRON MICROSCOPE SAMPLE                                           
REMARK 245   SAMPLE TYPE                    : PARTICLE                          
REMARK 245   PARTICLE TYPE                  : POINT                             
REMARK 245   NAME OF SAMPLE                 : QUATERNARY COMPLEX OF HUMAN       
REMARK 245                                    ALPHA-V BETA-3 INTEGRIN WITH      
REMARK 245                                    THE FAB LM609                     
REMARK 245   SAMPLE CONCENTRATION (MG ML-1) : NULL                              
REMARK 245   SAMPLE SUPPORT DETAILS         : NULL                              
REMARK 245   SAMPLE VITRIFICATION DETAILS   : NULL                              
REMARK 245   SAMPLE BUFFER                  : NULL                              
REMARK 245   PH                             : 8.00                              
REMARK 245   SAMPLE DETAILS                 : NULL                              
REMARK 245                                                                      
REMARK 245 DATA ACQUISITION                                                     
REMARK 245   DATE OF EXPERIMENT                : NULL                           
REMARK 245   NUMBER OF MICROGRAPHS-IMAGES      : NULL                           
REMARK 245   TEMPERATURE (KELVIN)              : NULL                           
REMARK 245   MICROSCOPE MODEL                  : FEI TECNAI 12                  
REMARK 245   DETECTOR TYPE                     : GATAN ULTRASCAN 4000 (4K X     
REMARK 245                                       4K)                            
REMARK 245   MINIMUM DEFOCUS (NM)              : NULL                           
REMARK 245   MAXIMUM DEFOCUS (NM)              : NULL                           
REMARK 245   MINIMUM TILT ANGLE (DEGREES)      : NULL                           
REMARK 245   MAXIMUM TILT ANGLE (DEGREES)      : NULL                           
REMARK 245   NOMINAL CS                        : NULL                           
REMARK 245   IMAGING MODE                      : BRIGHT FIELD                   
REMARK 245   ELECTRON DOSE (ELECTRONS NM**-2)  : 30.00                          
REMARK 245   ILLUMINATION MODE                 : FLOOD BEAM                     
REMARK 245   NOMINAL MAGNIFICATION             : NULL                           
REMARK 245   CALIBRATED MAGNIFICATION          : NULL                           
REMARK 245   SOURCE                            : LAB6                           
REMARK 245   ACCELERATION VOLTAGE (KV)         : 120                            
REMARK 245   IMAGING DETAILS                   : NULL                           
REMARK 247                                                                      
REMARK 247 ELECTRON MICROSCOPY                                                  
REMARK 247  THE COORDINATES IN THIS ENTRY WERE GENERATED FROM ELECTRON          
REMARK 247  MICROSCOPY DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE              
REMARK 247  THAT CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES           
REMARK 247  ON THESE RECORDS ARE MEANINGLESS EXCEPT FOR THE CALCULATION         
REMARK 247  OF THE STRUCTURE FACTORS.                                           
REMARK 300                                                                      
REMARK 300 BIOMOLECULE: 1                                                       
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM                
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN                  
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON               
REMARK 300 BURIED SURFACE AREA.                                                 
REMARK 350                                                                      
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN           
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE                
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS          
REMARK 350 GIVEN BELOW.  BOTH NON-CRYSTALLOGRAPHIC AND                          
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.                               
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 1                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TETRAMERIC                        
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B, H, L                            
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 465                                                                      
REMARK 465 MISSING RESIDUES                                                     
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE                       
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)                
REMARK 465                                                                      
REMARK 465   M RES C SSSEQI                                                     
REMARK 465     GLN A   839                                                      
REMARK 465     THR A   840                                                      
REMARK 465     THR A   841                                                      
REMARK 465     GLU A   842                                                      
REMARK 465     LYS A   843                                                      
REMARK 465     ASN A   844                                                      
REMARK 465     ASP A   845                                                      
REMARK 465     THR A   846                                                      
REMARK 465     VAL A   847                                                      
REMARK 465     ALA A   848                                                      
REMARK 465     GLY A   849                                                      
REMARK 465     GLN A   850                                                      
REMARK 465     GLY A   851                                                      
REMARK 465     GLU A   852                                                      
REMARK 465     ARG A   853                                                      
REMARK 465     ASP A   854                                                      
REMARK 465     HIS A   855                                                      
REMARK 465     LEU A   856                                                      
REMARK 465     ILE A   857                                                      
REMARK 465     THR A   858                                                      
REMARK 465     LYS A   859                                                      
REMARK 465     ARG A   860                                                      
REMARK 465     ASP A   861                                                      
REMARK 465     LEU A   862                                                      
REMARK 465     ALA A   863                                                      
REMARK 465     LEU A   864                                                      
REMARK 465     SER A   865                                                      
REMARK 465     GLU A   866                                                      
REMARK 465     GLY A   867                                                      
REMARK 465     GLY A   954                                                      
REMARK 465     ILE A   955                                                      
REMARK 465     GLN A   956                                                      
REMARK 465     PRO A   957                                                      
REMARK 465     GLU B   686                                                      
REMARK 465     CYS B   687                                                      
REMARK 465     PRO B   688                                                      
REMARK 465     LYS B   689                                                      
REMARK 465     GLY B   690                                                      
REMARK 465     PRO B   691                                                      
REMARK 465     ASP B   692                                                      
REMARK 465     ALA H   133                                                      
REMARK 465     ALA H   134                                                      
REMARK 465     GLN H   135                                                      
REMARK 465     ASP H   218                                                      
REMARK 465     CYS H   219                                                      
REMARK 465     GLY H   220                                                      
REMARK 465     ALA H   221                                                      
REMARK 465     SER H   222                                                      
REMARK 465     ASP H   223                                                      
REMARK 465     ASP H   224                                                      
REMARK 465     ASP H   225                                                      
REMARK 465     ASP H   226                                                      
REMARK 465     LYS H   227                                                      
REMARK 465     ALA H   228                                                      
REMARK 465     GLY H   229                                                      
REMARK 465     TRP H   230                                                      
REMARK 465     SER H   231                                                      
REMARK 465     HIS H   232                                                      
REMARK 465     PRO H   233                                                      
REMARK 465     GLN H   234                                                      
REMARK 465     PHE H   235                                                      
REMARK 465     GLU H   236                                                      
REMARK 465     LYS H   237                                                      
REMARK 465     GLY H   238                                                      
REMARK 465     GLY H   239                                                      
REMARK 465     GLY H   240                                                      
REMARK 465     SER H   241                                                      
REMARK 465     GLY H   242                                                      
REMARK 465     GLY H   243                                                      
REMARK 465     GLY H   244                                                      
REMARK 465     SER H   245                                                      
REMARK 465     GLY H   246                                                      
REMARK 465     GLY H   247                                                      
REMARK 465     GLY H   248                                                      
REMARK 465     SER H   249                                                      
REMARK 465     TRP H   250                                                      
REMARK 465     SER H   251                                                      
REMARK 465     HIS H   252                                                      
REMARK 465     PRO H   253                                                      
REMARK 465     GLN H   254                                                      
REMARK 465     PHE H   255                                                      
REMARK 465     GLU H   256                                                      
REMARK 465     LYS H   257                                                      
REMARK 465     GLU L     1                                                      
REMARK 465     THR L   202                                                      
REMARK 465     CYS L   214                                                      
REMARK 470                                                                      
REMARK 470 MISSING ATOM                                                         
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;           
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;          
REMARK 470 I=INSERTION CODE):                                                   
REMARK 470   M RES CSSEQI  ATOMS                                                
REMARK 470     PHE A   1    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASN A   2    CG   OD1  ND2                                       
REMARK 470     LEU A   3    CG   CD1  CD2                                       
REMARK 470     ASP A   4    CG   OD1  OD2                                       
REMARK 470     VAL A   5    CG1  CG2                                            
REMARK 470     ASP A   6    CG   OD1  OD2                                       
REMARK 470     SER A   7    OG                                                  
REMARK 470     PRO A   8    CG   CD                                             
REMARK 470     GLU A  10    CG   CD   OE1  OE2                                  
REMARK 470     TYR A  11    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     SER A  12    OG                                                  
REMARK 470     PRO A  14    CG   CD                                             
REMARK 470     GLU A  15    CG   CD   OE1  OE2                                  
REMARK 470     SER A  17    OG                                                  
REMARK 470     TYR A  18    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     PHE A  19    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     PHE A  21    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     VAL A  23    CG1  CG2                                            
REMARK 470     ASP A  24    CG   OD1  OD2                                       
REMARK 470     PHE A  25    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     PHE A  26    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     VAL A  27    CG1  CG2                                            
REMARK 470     PRO A  28    CG   CD                                             
REMARK 470     SER A  29    OG                                                  
REMARK 470     SER A  31    OG                                                  
REMARK 470     SER A  32    OG                                                  
REMARK 470     ARG A  33    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     MET A  34    CG   SD   CE                                        
REMARK 470     PHE A  35    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     LEU A  36    CG   CD1  CD2                                       
REMARK 470     LEU A  37    CG   CD1  CD2                                       
REMARK 470     VAL A  38    CG1  CG2                                            
REMARK 470     PRO A  41    CG   CD                                             
REMARK 470     LYS A  42    CG   CD   CE   NZ                                   
REMARK 470     ASN A  44    CG   OD1  ND2                                       
REMARK 470     THR A  45    OG1  CG2                                            
REMARK 470     THR A  46    OG1  CG2                                            
REMARK 470     GLN A  47    CG   CD   OE1  NE2                                  
REMARK 470     PRO A  48    CG   CD                                             
REMARK 470     ILE A  50    CG1  CG2  CD1                                       
REMARK 470     VAL A  51    CG1  CG2                                            
REMARK 470     GLU A  52    CG   CD   OE1  OE2                                  
REMARK 470     GLN A  55    CG   CD   OE1  NE2                                  
REMARK 470     VAL A  56    CG1  CG2                                            
REMARK 470     LEU A  57    CG   CD1  CD2                                       
REMARK 470     LYS A  58    CG   CD   CE   NZ                                   
REMARK 470     CYS A  59    SG                                                  
REMARK 470     ASP A  60    CG   OD1  OD2                                       
REMARK 470     TRP A  61    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP A  61    CZ3  CH2                                            
REMARK 470     SER A  62    OG                                                  
REMARK 470     SER A  63    OG                                                  
REMARK 470     THR A  64    OG1  CG2                                            
REMARK 470     ARG A  65    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG A  66    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     CYS A  67    SG                                                  
REMARK 470     GLN A  68    CG   CD   OE1  NE2                                  
REMARK 470     PRO A  69    CG   CD                                             
REMARK 470     ILE A  70    CG1  CG2  CD1                                       
REMARK 470     GLU A  71    CG   CD   OE1  OE2                                  
REMARK 470     PHE A  72    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASP A  73    CG   OD1  OD2                                       
REMARK 470     THR A  75    OG1  CG2                                            
REMARK 470     ASN A  77    CG   OD1  ND2                                       
REMARK 470     ARG A  78    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP A  79    CG   OD1  OD2                                       
REMARK 470     TYR A  80    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LYS A  82    CG   CD   CE   NZ                                   
REMARK 470     ASP A  83    CG   OD1  OD2                                       
REMARK 470     ASP A  84    CG   OD1  OD2                                       
REMARK 470     PRO A  85    CG   CD                                             
REMARK 470     LEU A  86    CG   CD1  CD2                                       
REMARK 470     GLU A  87    CG   CD   OE1  OE2                                  
REMARK 470     PHE A  88    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     LYS A  89    CG   CD   CE   NZ                                   
REMARK 470     SER A  90    OG                                                  
REMARK 470     HIS A  91    CG   ND1  CD2  CE1  NE2                             
REMARK 470     GLN A  92    CG   CD   OE1  NE2                                  
REMARK 470     TRP A  93    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP A  93    CZ3  CH2                                            
REMARK 470     PHE A  94    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     SER A  97    OG                                                  
REMARK 470     VAL A  98    CG1  CG2                                            
REMARK 470     ARG A  99    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     SER A 100    OG                                                  
REMARK 470     LYS A 101    CG   CD   CE   NZ                                   
REMARK 470     GLN A 102    CG   CD   OE1  NE2                                  
REMARK 470     ASP A 103    CG   OD1  OD2                                       
REMARK 470     LYS A 104    CG   CD   CE   NZ                                   
REMARK 470     ILE A 105    CG1  CG2  CD1                                       
REMARK 470     LEU A 106    CG   CD1  CD2                                       
REMARK 470     CYS A 108    SG                                                  
REMARK 470     PRO A 110    CG   CD                                             
REMARK 470     LEU A 111    CG   CD1  CD2                                       
REMARK 470     TYR A 112    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     HIS A 113    CG   ND1  CD2  CE1  NE2                             
REMARK 470     TRP A 114    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP A 114    CZ3  CH2                                            
REMARK 470     ARG A 115    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     THR A 116    OG1  CG2                                            
REMARK 470     GLU A 117    CG   CD   OE1  OE2                                  
REMARK 470     MET A 118    CG   SD   CE                                        
REMARK 470     LYS A 119    CG   CD   CE   NZ                                   
REMARK 470     GLN A 120    CG   CD   OE1  NE2                                  
REMARK 470     GLU A 121    CG   CD   OE1  OE2                                  
REMARK 470     ARG A 122    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU A 123    CG   CD   OE1  OE2                                  
REMARK 470     PRO A 124    CG   CD                                             
REMARK 470     VAL A 125    CG1  CG2                                            
REMARK 470     THR A 127    OG1  CG2                                            
REMARK 470     CYS A 128    SG                                                  
REMARK 470     PHE A 129    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     LEU A 130    CG   CD1  CD2                                       
REMARK 470     GLN A 131    CG   CD   OE1  NE2                                  
REMARK 470     ASP A 132    CG   OD1  OD2                                       
REMARK 470     THR A 134    OG1  CG2                                            
REMARK 470     LYS A 135    CG   CD   CE   NZ                                   
REMARK 470     THR A 136    OG1  CG2                                            
REMARK 470     VAL A 137    CG1  CG2                                            
REMARK 470     GLU A 138    CG   CD   OE1  OE2                                  
REMARK 470     TYR A 139    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     PRO A 141    CG   CD                                             
REMARK 470     CYS A 142    SG                                                  
REMARK 470     ARG A 143    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     SER A 144    OG                                                  
REMARK 470     GLN A 145    CG   CD   OE1  NE2                                  
REMARK 470     ASP A 146    CG   OD1  OD2                                       
REMARK 470     ILE A 147    CG1  CG2  CD1                                       
REMARK 470     ASP A 148    CG   OD1  OD2                                       
REMARK 470     ASP A 150    CG   OD1  OD2                                       
REMARK 470     GLN A 152    CG   CD   OE1  NE2                                  
REMARK 470     PHE A 154    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     CYS A 155    SG                                                  
REMARK 470     GLN A 156    CG   CD   OE1  NE2                                  
REMARK 470     PHE A 159    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     SER A 160    OG                                                  
REMARK 470     ILE A 161    CG1  CG2  CD1                                       
REMARK 470     ASP A 162    CG   OD1  OD2                                       
REMARK 470     PHE A 163    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     THR A 164    OG1  CG2                                            
REMARK 470     LYS A 165    CG   CD   CE   NZ                                   
REMARK 470     ASP A 167    CG   OD1  OD2                                       
REMARK 470     ARG A 168    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     VAL A 169    CG1  CG2                                            
REMARK 470     LEU A 170    CG   CD1  CD2                                       
REMARK 470     LEU A 171    CG   CD1  CD2                                       
REMARK 470     PRO A 174    CG   CD                                             
REMARK 470     SER A 176    OG                                                  
REMARK 470     PHE A 177    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     TYR A 178    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     TRP A 179    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP A 179    CZ3  CH2                                            
REMARK 470     GLN A 180    CG   CD   OE1  NE2                                  
REMARK 470     GLN A 182    CG   CD   OE1  NE2                                  
REMARK 470     LEU A 183    CG   CD1  CD2                                       
REMARK 470     ILE A 184    CG1  CG2  CD1                                       
REMARK 470     SER A 185    OG                                                  
REMARK 470     ASP A 186    CG   OD1  OD2                                       
REMARK 470     GLN A 187    CG   CD   OE1  NE2                                  
REMARK 470     VAL A 188    CG1  CG2                                            
REMARK 470     GLU A 190    CG   CD   OE1  OE2                                  
REMARK 470     ILE A 191    CG1  CG2  CD1                                       
REMARK 470     VAL A 192    CG1  CG2                                            
REMARK 470     SER A 193    OG                                                  
REMARK 470     LYS A 194    CG   CD   CE   NZ                                   
REMARK 470     TYR A 195    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ASP A 196    CG   OD1  OD2                                       
REMARK 470     PRO A 197    CG   CD                                             
REMARK 470     ASN A 198    CG   OD1  ND2                                       
REMARK 470     VAL A 199    CG1  CG2                                            
REMARK 470     TYR A 200    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     SER A 201    OG                                                  
REMARK 470     ILE A 202    CG1  CG2  CD1                                       
REMARK 470     LYS A 203    CG   CD   CE   NZ                                   
REMARK 470     TYR A 204    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ASN A 205    CG   OD1  ND2                                       
REMARK 470     ASN A 206    CG   OD1  ND2                                       
REMARK 470     GLN A 207    CG   CD   OE1  NE2                                  
REMARK 470     LEU A 208    CG   CD1  CD2                                       
REMARK 470     THR A 210    OG1  CG2                                            
REMARK 470     ARG A 211    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     THR A 212    OG1  CG2                                            
REMARK 470     GLN A 214    CG   CD   OE1  NE2                                  
REMARK 470     ILE A 216    CG1  CG2  CD1                                       
REMARK 470     PHE A 217    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASP A 218    CG   OD1  OD2                                       
REMARK 470     ASP A 219    CG   OD1  OD2                                       
REMARK 470     SER A 220    OG                                                  
REMARK 470     TYR A 221    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LEU A 222    CG   CD1  CD2                                       
REMARK 470     TYR A 224    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     SER A 225    OG                                                  
REMARK 470     VAL A 226    CG1  CG2                                            
REMARK 470     VAL A 228    CG1  CG2                                            
REMARK 470     ASP A 230    CG   OD1  OD2                                       
REMARK 470     PHE A 231    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASN A 232    CG   OD1  ND2                                       
REMARK 470     ASP A 234    CG   OD1  OD2                                       
REMARK 470     ILE A 236    CG1  CG2  CD1                                       
REMARK 470     ASP A 237    CG   OD1  OD2                                       
REMARK 470     ASP A 238    CG   OD1  OD2                                       
REMARK 470     PHE A 239    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     VAL A 240    CG1  CG2                                            
REMARK 470     SER A 241    OG                                                  
REMARK 470     VAL A 243    CG1  CG2                                            
REMARK 470     PRO A 244    CG   CD                                             
REMARK 470     ARG A 245    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG A 248    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     THR A 249    OG1  CG2                                            
REMARK 470     LEU A 250    CG   CD1  CD2                                       
REMARK 470     MET A 252    CG   SD   CE                                        
REMARK 470     VAL A 253    CG1  CG2                                            
REMARK 470     TYR A 254    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ILE A 255    CG1  CG2  CD1                                       
REMARK 470     TYR A 256    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ASP A 257    CG   OD1  OD2                                       
REMARK 470     LYS A 259    CG   CD   CE   NZ                                   
REMARK 470     ASN A 260    CG   OD1  ND2                                       
REMARK 470     MET A 261    CG   SD   CE                                        
REMARK 470     SER A 262    OG                                                  
REMARK 470     SER A 263    OG                                                  
REMARK 470     LEU A 264    CG   CD1  CD2                                       
REMARK 470     TYR A 265    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ASN A 266    CG   OD1  ND2                                       
REMARK 470     PHE A 267    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     THR A 268    OG1  CG2                                            
REMARK 470     GLU A 270    CG   CD   OE1  OE2                                  
REMARK 470     GLN A 271    CG   CD   OE1  NE2                                  
REMARK 470     MET A 272    CG   SD   CE                                        
REMARK 470     TYR A 275    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     PHE A 276    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     PHE A 278    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     SER A 279    OG                                                  
REMARK 470     VAL A 280    CG1  CG2                                            
REMARK 470     THR A 283    OG1  CG2                                            
REMARK 470     ASP A 284    CG   OD1  OD2                                       
REMARK 470     ILE A 285    CG1  CG2  CD1                                       
REMARK 470     ASN A 286    CG   OD1  ND2                                       
REMARK 470     ASP A 288    CG   OD1  OD2                                       
REMARK 470     ASP A 289    CG   OD1  OD2                                       
REMARK 470     TYR A 290    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ASP A 292    CG   OD1  OD2                                       
REMARK 470     VAL A 293    CG1  CG2                                            
REMARK 470     PHE A 294    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ILE A 295    CG1  CG2  CD1                                       
REMARK 470     PRO A 298    CG   CD                                             
REMARK 470     LEU A 299    CG   CD1  CD2                                       
REMARK 470     PHE A 300    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     MET A 301    CG   SD   CE                                        
REMARK 470     ASP A 302    CG   OD1  OD2                                       
REMARK 470     ARG A 303    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     SER A 305    OG                                                  
REMARK 470     ASP A 306    CG   OD1  OD2                                       
REMARK 470     LYS A 308    CG   CD   CE   NZ                                   
REMARK 470     LEU A 309    CG   CD1  CD2                                       
REMARK 470     GLN A 310    CG   CD   OE1  NE2                                  
REMARK 470     GLU A 311    CG   CD   OE1  OE2                                  
REMARK 470     VAL A 312    CG1  CG2                                            
REMARK 470     GLN A 314    CG   CD   OE1  NE2                                  
REMARK 470     VAL A 315    CG1  CG2                                            
REMARK 470     SER A 316    OG                                                  
REMARK 470     VAL A 317    CG1  CG2                                            
REMARK 470     SER A 318    OG                                                  
REMARK 470     LEU A 319    CG   CD1  CD2                                       
REMARK 470     GLN A 320    CG   CD   OE1  NE2                                  
REMARK 470     ARG A 321    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     SER A 323    OG                                                  
REMARK 470     ASP A 325    CG   OD1  OD2                                       
REMARK 470     PHE A 326    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLN A 327    CG   CD   OE1  NE2                                  
REMARK 470     THR A 328    OG1  CG2                                            
REMARK 470     THR A 329    OG1  CG2                                            
REMARK 470     LYS A 330    CG   CD   CE   NZ                                   
REMARK 470     LEU A 331    CG   CD1  CD2                                       
REMARK 470     ASN A 332    CG   OD1  ND2                                       
REMARK 470     PHE A 334    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLU A 335    CG   CD   OE1  OE2                                  
REMARK 470     VAL A 336    CG1  CG2                                            
REMARK 470     PHE A 337    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ARG A 339    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     PHE A 340    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     SER A 342    OG                                                  
REMARK 470     ILE A 344    CG1  CG2  CD1                                       
REMARK 470     PRO A 346    CG   CD                                             
REMARK 470     LEU A 347    CG   CD1  CD2                                       
REMARK 470     ASP A 349    CG   OD1  OD2                                       
REMARK 470     LEU A 350    CG   CD1  CD2                                       
REMARK 470     ASP A 351    CG   OD1  OD2                                       
REMARK 470     GLN A 352    CG   CD   OE1  NE2                                  
REMARK 470     ASP A 353    CG   OD1  OD2                                       
REMARK 470     PHE A 355    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASN A 356    CG   OD1  ND2                                       
REMARK 470     ASP A 357    CG   OD1  OD2                                       
REMARK 470     ILE A 358    CG1  CG2  CD1                                       
REMARK 470     ILE A 360    CG1  CG2  CD1                                       
REMARK 470     PRO A 363    CG   CD                                             
REMARK 470     TYR A 364    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     GLU A 367    CG   CD   OE1  OE2                                  
REMARK 470     ASP A 368    CG   OD1  OD2                                       
REMARK 470     LYS A 369    CG   CD   CE   NZ                                   
REMARK 470     LYS A 370    CG   CD   CE   NZ                                   
REMARK 470     ILE A 372    CG1  CG2  CD1                                       
REMARK 470     VAL A 373    CG1  CG2                                            
REMARK 470     TYR A 374    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ILE A 375    CG1  CG2  CD1                                       
REMARK 470     PHE A 376    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASN A 377    CG   OD1  ND2                                       
REMARK 470     ARG A 379    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     SER A 380    OG                                                  
REMARK 470     THR A 381    OG1  CG2                                            
REMARK 470     LEU A 383    CG   CD1  CD2                                       
REMARK 470     ASN A 384    CG   OD1  ND2                                       
REMARK 470     VAL A 386    CG1  CG2                                            
REMARK 470     PRO A 387    CG   CD                                             
REMARK 470     SER A 388    OG                                                  
REMARK 470     GLN A 389    CG   CD   OE1  NE2                                  
REMARK 470     ILE A 390    CG1  CG2  CD1                                       
REMARK 470     LEU A 391    CG   CD1  CD2                                       
REMARK 470     GLU A 392    CG   CD   OE1  OE2                                  
REMARK 470     GLN A 394    CG   CD   OE1  NE2                                  
REMARK 470     TRP A 395    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP A 395    CZ3  CH2                                            
REMARK 470     ARG A 398    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     SER A 399    OG                                                  
REMARK 470     MET A 400    CG   SD   CE                                        
REMARK 470     PRO A 401    CG   CD                                             
REMARK 470     PRO A 402    CG   CD                                             
REMARK 470     SER A 403    OG                                                  
REMARK 470     PHE A 404    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     TYR A 406    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     SER A 407    OG                                                  
REMARK 470     MET A 408    CG   SD   CE                                        
REMARK 470     LYS A 409    CG   CD   CE   NZ                                   
REMARK 470     THR A 412    OG1  CG2                                            
REMARK 470     ASP A 413    CG   OD1  OD2                                       
REMARK 470     ILE A 414    CG1  CG2  CD1                                       
REMARK 470     ASP A 415    CG   OD1  OD2                                       
REMARK 470     LYS A 416    CG   CD   CE   NZ                                   
REMARK 470     ASN A 417    CG   OD1  ND2                                       
REMARK 470     TYR A 419    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     PRO A 420    CG   CD                                             
REMARK 470     ASP A 421    CG   OD1  OD2                                       
REMARK 470     LEU A 422    CG   CD1  CD2                                       
REMARK 470     ILE A 423    CG1  CG2  CD1                                       
REMARK 470     VAL A 424    CG1  CG2                                            
REMARK 470     PHE A 427    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     VAL A 429    CG1  CG2                                            
REMARK 470     ASP A 430    CG   OD1  OD2                                       
REMARK 470     ARG A 431    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ILE A 433    CG1  CG2  CD1                                       
REMARK 470     LEU A 434    CG   CD1  CD2                                       
REMARK 470     TYR A 435    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ARG A 436    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG A 438    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     PRO A 439    CG   CD                                             
REMARK 470     VAL A 440    CG1  CG2                                            
REMARK 470     ILE A 441    CG1  CG2  CD1                                       
REMARK 470     THR A 442    OG1  CG2                                            
REMARK 470     VAL A 443    CG1  CG2                                            
REMARK 470     ASN A 444    CG   OD1  ND2                                       
REMARK 470     LEU A 447    CG   CD1  CD2                                       
REMARK 470     GLU A 448    CG   CD   OE1  OE2                                  
REMARK 470     VAL A 449    CG1  CG2                                            
REMARK 470     TYR A 450    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     PRO A 451    CG   CD                                             
REMARK 470     SER A 452    OG                                                  
REMARK 470     ILE A 453    CG1  CG2  CD1                                       
REMARK 470     LEU A 454    CG   CD1  CD2                                       
REMARK 470     ASN A 455    CG   OD1  ND2                                       
REMARK 470     GLN A 456    CG   CD   OE1  NE2                                  
REMARK 470     ASP A 457    CG   OD1  OD2                                       
REMARK 470     ASN A 458    CG   OD1  ND2                                       
REMARK 470     LYS A 459    CG   CD   CE   NZ                                   
REMARK 470     THR A 460    OG1  CG2                                            
REMARK 470     CYS A 461    SG                                                  
REMARK 470     SER A 462    OG                                                  
REMARK 470     LEU A 463    CG   CD1  CD2                                       
REMARK 470     PRO A 464    CG   CD                                             
REMARK 470     THR A 466    OG1  CG2                                            
REMARK 470     LEU A 468    CG   CD1  CD2                                       
REMARK 470     LYS A 469    CG   CD   CE   NZ                                   
REMARK 470     VAL A 470    CG1  CG2                                            
REMARK 470     SER A 471    OG                                                  
REMARK 470     CYS A 472    SG                                                  
REMARK 470     PHE A 473    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASN A 474    CG   OD1  ND2                                       
REMARK 470     VAL A 475    CG1  CG2                                            
REMARK 470     ARG A 476    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     PHE A 477    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     CYS A 478    SG                                                  
REMARK 470     LEU A 479    CG   CD1  CD2                                       
REMARK 470     LYS A 480    CG   CD   CE   NZ                                   
REMARK 470     ASP A 482    CG   OD1  OD2                                       
REMARK 470     LYS A 484    CG   CD   CE   NZ                                   
REMARK 470     VAL A 486    CG1  CG2                                            
REMARK 470     LEU A 487    CG   CD1  CD2                                       
REMARK 470     PRO A 488    CG   CD                                             
REMARK 470     ARG A 489    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS A 490    CG   CD   CE   NZ                                   
REMARK 470     LEU A 491    CG   CD1  CD2                                       
REMARK 470     ASN A 492    CG   OD1  ND2                                       
REMARK 470     PHE A 493    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLN A 494    CG   CD   OE1  NE2                                  
REMARK 470     VAL A 495    CG1  CG2                                            
REMARK 470     GLU A 496    CG   CD   OE1  OE2                                  
REMARK 470     LEU A 497    CG   CD1  CD2                                       
REMARK 470     LEU A 498    CG   CD1  CD2                                       
REMARK 470     LEU A 499    CG   CD1  CD2                                       
REMARK 470     ASP A 500    CG   OD1  OD2                                       
REMARK 470     LYS A 501    CG   CD   CE   NZ                                   
REMARK 470     LEU A 502    CG   CD1  CD2                                       
REMARK 470     LYS A 503    CG   CD   CE   NZ                                   
REMARK 470     GLN A 504    CG   CD   OE1  NE2                                  
REMARK 470     LYS A 505    CG   CD   CE   NZ                                   
REMARK 470     ILE A 508    CG1  CG2  CD1                                       
REMARK 470     ARG A 509    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG A 510    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU A 512    CG   CD1  CD2                                       
REMARK 470     PHE A 513    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     LEU A 514    CG   CD1  CD2                                       
REMARK 470     TYR A 515    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     SER A 516    OG                                                  
REMARK 470     ARG A 517    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     SER A 518    OG                                                  
REMARK 470     PRO A 519    CG   CD                                             
REMARK 470     SER A 520    OG                                                  
REMARK 470     HIS A 521    CG   ND1  CD2  CE1  NE2                             
REMARK 470     SER A 522    OG                                                  
REMARK 470     LYS A 523    CG   CD   CE   NZ                                   
REMARK 470     ASN A 524    CG   OD1  ND2                                       
REMARK 470     MET A 525    CG   SD   CE                                        
REMARK 470     THR A 526    OG1  CG2                                            
REMARK 470     ILE A 527    CG1  CG2  CD1                                       
REMARK 470     SER A 528    OG                                                  
REMARK 470     ARG A 529    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU A 532    CG   CD1  CD2                                       
REMARK 470     MET A 533    CG   SD   CE                                        
REMARK 470     GLN A 534    CG   CD   OE1  NE2                                  
REMARK 470     CYS A 535    SG                                                  
REMARK 470     GLU A 536    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 537    CG   CD   OE1  OE2                                  
REMARK 470     LEU A 538    CG   CD1  CD2                                       
REMARK 470     ILE A 539    CG1  CG2  CD1                                       
REMARK 470     TYR A 541    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LEU A 542    CG   CD1  CD2                                       
REMARK 470     ARG A 543    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP A 544    CG   OD1  OD2                                       
REMARK 470     GLU A 545    CG   CD   OE1  OE2                                  
REMARK 470     SER A 546    OG                                                  
REMARK 470     GLU A 547    CG   CD   OE1  OE2                                  
REMARK 470     PHE A 548    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ARG A 549    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP A 550    CG   OD1  OD2                                       
REMARK 470     LYS A 551    CG   CD   CE   NZ                                   
REMARK 470     LEU A 552    CG   CD1  CD2                                       
REMARK 470     THR A 553    OG1  CG2                                            
REMARK 470     PRO A 554    CG   CD                                             
REMARK 470     ILE A 555    CG1  CG2  CD1                                       
REMARK 470     THR A 556    OG1  CG2                                            
REMARK 470     ILE A 557    CG1  CG2  CD1                                       
REMARK 470     PHE A 558    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     MET A 559    CG   SD   CE                                        
REMARK 470     GLU A 560    CG   CD   OE1  OE2                                  
REMARK 470     TYR A 561    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ARG A 562    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU A 563    CG   CD1  CD2                                       
REMARK 470     ASP A 564    CG   OD1  OD2                                       
REMARK 470     TYR A 565    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ARG A 566    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     THR A 567    OG1  CG2                                            
REMARK 470     ASP A 570    CG   OD1  OD2                                       
REMARK 470     THR A 571    OG1  CG2                                            
REMARK 470     THR A 572    OG1  CG2                                            
REMARK 470     LEU A 574    CG   CD1  CD2                                       
REMARK 470     GLN A 575    CG   CD   OE1  NE2                                  
REMARK 470     PRO A 576    CG   CD                                             
REMARK 470     ILE A 577    CG1  CG2  CD1                                       
REMARK 470     LEU A 578    CG   CD1  CD2                                       
REMARK 470     ASN A 579    CG   OD1  ND2                                       
REMARK 470     GLN A 580    CG   CD   OE1  NE2                                  
REMARK 470     PHE A 581    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     THR A 582    OG1  CG2                                            
REMARK 470     PRO A 583    CG   CD                                             
REMARK 470     ASN A 585    CG   OD1  ND2                                       
REMARK 470     ILE A 586    CG1  CG2  CD1                                       
REMARK 470     SER A 587    OG                                                  
REMARK 470     ARG A 588    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLN A 589    CG   CD   OE1  NE2                                  
REMARK 470     HIS A 591    CG   ND1  CD2  CE1  NE2                             
REMARK 470     ILE A 592    CG1  CG2  CD1                                       
REMARK 470     LEU A 593    CG   CD1  CD2                                       
REMARK 470     LEU A 594    CG   CD1  CD2                                       
REMARK 470     ASP A 595    CG   OD1  OD2                                       
REMARK 470     CYS A 596    SG                                                  
REMARK 470     GLU A 598    CG   CD   OE1  OE2                                  
REMARK 470     ASP A 599    CG   OD1  OD2                                       
REMARK 470     ASN A 600    CG   OD1  ND2                                       
REMARK 470     VAL A 601    CG1  CG2                                            
REMARK 470     CYS A 602    SG                                                  
REMARK 470     LYS A 603    CG   CD   CE   NZ                                   
REMARK 470     PRO A 604    CG   CD                                             
REMARK 470     LYS A 605    CG   CD   CE   NZ                                   
REMARK 470     LEU A 606    CG   CD1  CD2                                       
REMARK 470     GLU A 607    CG   CD   OE1  OE2                                  
REMARK 470     VAL A 608    CG1  CG2                                            
REMARK 470     SER A 609    OG                                                  
REMARK 470     VAL A 610    CG1  CG2                                            
REMARK 470     ASP A 611    CG   OD1  OD2                                       
REMARK 470     SER A 612    OG                                                  
REMARK 470     ASP A 613    CG   OD1  OD2                                       
REMARK 470     GLN A 614    CG   CD   OE1  NE2                                  
REMARK 470     LYS A 615    CG   CD   CE   NZ                                   
REMARK 470     LYS A 616    CG   CD   CE   NZ                                   
REMARK 470     ILE A 617    CG1  CG2  CD1                                       
REMARK 470     TYR A 618    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ILE A 619    CG1  CG2  CD1                                       
REMARK 470     ASP A 621    CG   OD1  OD2                                       
REMARK 470     ASP A 622    CG   OD1  OD2                                       
REMARK 470     ASN A 623    CG   OD1  ND2                                       
REMARK 470     PRO A 624    CG   CD                                             
REMARK 470     LEU A 625    CG   CD1  CD2                                       
REMARK 470     THR A 626    OG1  CG2                                            
REMARK 470     LEU A 627    CG   CD1  CD2                                       
REMARK 470     ILE A 628    CG1  CG2  CD1                                       
REMARK 470     VAL A 629    CG1  CG2                                            
REMARK 470     LYS A 630    CG   CD   CE   NZ                                   
REMARK 470     GLN A 632    CG   CD   OE1  NE2                                  
REMARK 470     ASN A 633    CG   OD1  ND2                                       
REMARK 470     GLN A 634    CG   CD   OE1  NE2                                  
REMARK 470     GLU A 636    CG   CD   OE1  OE2                                  
REMARK 470     TYR A 639    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     GLU A 640    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 642    CG   CD   OE1  OE2                                  
REMARK 470     LEU A 643    CG   CD1  CD2                                       
REMARK 470     ILE A 644    CG1  CG2  CD1                                       
REMARK 470     VAL A 645    CG1  CG2                                            
REMARK 470     SER A 646    OG                                                  
REMARK 470     ILE A 647    CG1  CG2  CD1                                       
REMARK 470     PRO A 648    CG   CD                                             
REMARK 470     LEU A 649    CG   CD1  CD2                                       
REMARK 470     GLN A 650    CG   CD   OE1  NE2                                  
REMARK 470     ASP A 652    CG   OD1  OD2                                       
REMARK 470     PHE A 653    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ILE A 654    CG1  CG2  CD1                                       
REMARK 470     VAL A 656    CG1  CG2                                            
REMARK 470     VAL A 657    CG1  CG2                                            
REMARK 470     ARG A 658    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASN A 659    CG   OD1  ND2                                       
REMARK 470     ASN A 660    CG   OD1  ND2                                       
REMARK 470     GLU A 661    CG   CD   OE1  OE2                                  
REMARK 470     LEU A 663    CG   CD1  CD2                                       
REMARK 470     ARG A 665    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU A 666    CG   CD1  CD2                                       
REMARK 470     SER A 667    OG                                                  
REMARK 470     CYS A 668    SG                                                  
REMARK 470     PHE A 670    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     LYS A 671    CG   CD   CE   NZ                                   
REMARK 470     THR A 672    OG1  CG2                                            
REMARK 470     GLU A 673    CG   CD   OE1  OE2                                  
REMARK 470     ASN A 674    CG   OD1  ND2                                       
REMARK 470     GLN A 675    CG   CD   OE1  NE2                                  
REMARK 470     THR A 676    OG1  CG2                                            
REMARK 470     ARG A 677    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLN A 678    CG   CD   OE1  NE2                                  
REMARK 470     VAL A 679    CG1  CG2                                            
REMARK 470     VAL A 680    CG1  CG2                                            
REMARK 470     CYS A 681    SG                                                  
REMARK 470     ASP A 682    CG   OD1  OD2                                       
REMARK 470     LEU A 683    CG   CD1  CD2                                       
REMARK 470     ASN A 685    CG   OD1  ND2                                       
REMARK 470     PRO A 686    CG   CD                                             
REMARK 470     MET A 687    CG   SD   CE                                        
REMARK 470     LYS A 688    CG   CD   CE   NZ                                   
REMARK 470     THR A 691    OG1  CG2                                            
REMARK 470     GLN A 692    CG   CD   OE1  NE2                                  
REMARK 470     LEU A 693    CG   CD1  CD2                                       
REMARK 470     LEU A 694    CG   CD1  CD2                                       
REMARK 470     LEU A 697    CG   CD1  CD2                                       
REMARK 470     ARG A 698    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     PHE A 699    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     SER A 700    OG                                                  
REMARK 470     VAL A 701    CG1  CG2                                            
REMARK 470     HIS A 702    CG   ND1  CD2  CE1  NE2                             
REMARK 470     GLN A 703    CG   CD   OE1  NE2                                  
REMARK 470     GLN A 704    CG   CD   OE1  NE2                                  
REMARK 470     SER A 705    OG                                                  
REMARK 470     GLU A 706    CG   CD   OE1  OE2                                  
REMARK 470     MET A 707    CG   SD   CE                                        
REMARK 470     ASP A 708    CG   OD1  OD2                                       
REMARK 470     THR A 709    OG1  CG2                                            
REMARK 470     SER A 710    OG                                                  
REMARK 470     VAL A 711    CG1  CG2                                            
REMARK 470     LYS A 712    CG   CD   CE   NZ                                   
REMARK 470     PHE A 713    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASP A 714    CG   OD1  OD2                                       
REMARK 470     LEU A 715    CG   CD1  CD2                                       
REMARK 470     GLN A 716    CG   CD   OE1  NE2                                  
REMARK 470     ILE A 717    CG1  CG2  CD1                                       
REMARK 470     GLN A 718    CG   CD   OE1  NE2                                  
REMARK 470     SER A 719    OG                                                  
REMARK 470     SER A 720    OG                                                  
REMARK 470     ASN A 721    CG   OD1  ND2                                       
REMARK 470     LEU A 722    CG   CD1  CD2                                       
REMARK 470     PHE A 723    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASP A 724    CG   OD1  OD2                                       
REMARK 470     LYS A 725    CG   CD   CE   NZ                                   
REMARK 470     VAL A 726    CG1  CG2                                            
REMARK 470     SER A 727    OG                                                  
REMARK 470     PRO A 728    CG   CD                                             
REMARK 470     VAL A 729    CG1  CG2                                            
REMARK 470     VAL A 730    CG1  CG2                                            
REMARK 470     SER A 731    OG                                                  
REMARK 470     HIS A 732    CG   ND1  CD2  CE1  NE2                             
REMARK 470     LYS A 733    CG   CD   CE   NZ                                   
REMARK 470     VAL A 734    CG1  CG2                                            
REMARK 470     ASP A 735    CG   OD1  OD2                                       
REMARK 470     LEU A 736    CG   CD1  CD2                                       
REMARK 470     VAL A 738    CG1  CG2                                            
REMARK 470     LEU A 739    CG   CD1  CD2                                       
REMARK 470     VAL A 742    CG1  CG2                                            
REMARK 470     GLU A 743    CG   CD   OE1  OE2                                  
REMARK 470     ILE A 744    CG1  CG2  CD1                                       
REMARK 470     ARG A 745    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     VAL A 747    CG1  CG2                                            
REMARK 470     SER A 748    OG                                                  
REMARK 470     SER A 749    OG                                                  
REMARK 470     PRO A 750    CG   CD                                             
REMARK 470     ASP A 751    CG   OD1  OD2                                       
REMARK 470     HIS A 752    CG   ND1  CD2  CE1  NE2                             
REMARK 470     ILE A 753    CG1  CG2  CD1                                       
REMARK 470     PHE A 754    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     LEU A 755    CG   CD1  CD2                                       
REMARK 470     PRO A 756    CG   CD                                             
REMARK 470     ILE A 757    CG1  CG2  CD1                                       
REMARK 470     PRO A 758    CG   CD                                             
REMARK 470     ASN A 759    CG   OD1  ND2                                       
REMARK 470     TRP A 760    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP A 760    CZ3  CH2                                            
REMARK 470     GLU A 761    CG   CD   OE1  OE2                                  
REMARK 470     HIS A 762    CG   ND1  CD2  CE1  NE2                             
REMARK 470     LYS A 763    CG   CD   CE   NZ                                   
REMARK 470     GLU A 764    CG   CD   OE1  OE2                                  
REMARK 470     ASN A 765    CG   OD1  ND2                                       
REMARK 470     PRO A 766    CG   CD                                             
REMARK 470     GLU A 767    CG   CD   OE1  OE2                                  
REMARK 470     THR A 768    OG1  CG2                                            
REMARK 470     GLU A 769    CG   CD   OE1  OE2                                  
REMARK 470     GLU A 770    CG   CD   OE1  OE2                                  
REMARK 470     ASP A 771    CG   OD1  OD2                                       
REMARK 470     VAL A 772    CG1  CG2                                            
REMARK 470     PRO A 774    CG   CD                                             
REMARK 470     VAL A 775    CG1  CG2                                            
REMARK 470     VAL A 776    CG1  CG2                                            
REMARK 470     GLN A 777    CG   CD   OE1  NE2                                  
REMARK 470     HIS A 778    CG   ND1  CD2  CE1  NE2                             
REMARK 470     ILE A 779    CG1  CG2  CD1                                       
REMARK 470     TYR A 780    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     GLU A 781    CG   CD   OE1  OE2                                  
REMARK 470     LEU A 782    CG   CD1  CD2                                       
REMARK 470     ARG A 783    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASN A 784    CG   OD1  ND2                                       
REMARK 470     ASN A 785    CG   OD1  ND2                                       
REMARK 470     PRO A 787    CG   CD                                             
REMARK 470     SER A 788    OG                                                  
REMARK 470     SER A 789    OG                                                  
REMARK 470     PHE A 790    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     SER A 791    OG                                                  
REMARK 470     LYS A 792    CG   CD   CE   NZ                                   
REMARK 470     MET A 794    CG   SD   CE                                        
REMARK 470     LEU A 795    CG   CD1  CD2                                       
REMARK 470     HIS A 796    CG   ND1  CD2  CE1  NE2                             
REMARK 470     LEU A 797    CG   CD1  CD2                                       
REMARK 470     GLN A 798    CG   CD   OE1  NE2                                  
REMARK 470     TRP A 799    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP A 799    CZ3  CH2                                            
REMARK 470     PRO A 800    CG   CD                                             
REMARK 470     TYR A 801    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LYS A 802    CG   CD   CE   NZ                                   
REMARK 470     TYR A 803    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ASN A 804    CG   OD1  ND2                                       
REMARK 470     ASN A 805    CG   OD1  ND2                                       
REMARK 470     ASN A 806    CG   OD1  ND2                                       
REMARK 470     THR A 807    OG1  CG2                                            
REMARK 470     LEU A 808    CG   CD1  CD2                                       
REMARK 470     LEU A 809    CG   CD1  CD2                                       
REMARK 470     TYR A 810    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ILE A 811    CG1  CG2  CD1                                       
REMARK 470     LEU A 812    CG   CD1  CD2                                       
REMARK 470     HIS A 813    CG   ND1  CD2  CE1  NE2                             
REMARK 470     TYR A 814    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ASP A 815    CG   OD1  OD2                                       
REMARK 470     ILE A 816    CG1  CG2  CD1                                       
REMARK 470     ASP A 817    CG   OD1  OD2                                       
REMARK 470     PRO A 819    CG   CD                                             
REMARK 470     MET A 820    CG   SD   CE                                        
REMARK 470     ASN A 821    CG   OD1  ND2                                       
REMARK 470     CYS A 822    SG                                                  
REMARK 470     THR A 823    OG1  CG2                                            
REMARK 470     SER A 824    OG                                                  
REMARK 470     ASP A 825    CG   OD1  OD2                                       
REMARK 470     MET A 826    CG   SD   CE                                        
REMARK 470     GLU A 827    CG   CD   OE1  OE2                                  
REMARK 470     ILE A 828    CG1  CG2  CD1                                       
REMARK 470     ASN A 829    CG   OD1  ND2                                       
REMARK 470     PRO A 830    CG   CD                                             
REMARK 470     LEU A 831    CG   CD1  CD2                                       
REMARK 470     ARG A 832    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ILE A 833    CG1  CG2  CD1                                       
REMARK 470     LYS A 834    CG   CD   CE   NZ                                   
REMARK 470     ILE A 835    CG1  CG2  CD1                                       
REMARK 470     SER A 836    OG                                                  
REMARK 470     SER A 837    OG                                                  
REMARK 470     LEU A 838    CG   CD1  CD2                                       
REMARK 470     ASP A 868    CG   OD1  OD2                                       
REMARK 470     ILE A 869    CG1  CG2  CD1                                       
REMARK 470     HIS A 870    CG   ND1  CD2  CE1  NE2                             
REMARK 470     THR A 871    OG1  CG2                                            
REMARK 470     LEU A 872    CG   CD1  CD2                                       
REMARK 470     CYS A 874    SG                                                  
REMARK 470     VAL A 876    CG1  CG2                                            
REMARK 470     GLN A 878    CG   CD   OE1  NE2                                  
REMARK 470     CYS A 879    SG                                                  
REMARK 470     LEU A 880    CG   CD1  CD2                                       
REMARK 470     LYS A 881    CG   CD   CE   NZ                                   
REMARK 470     ILE A 882    CG1  CG2  CD1                                       
REMARK 470     VAL A 883    CG1  CG2                                            
REMARK 470     CYS A 884    SG                                                  
REMARK 470     GLN A 885    CG   CD   OE1  NE2                                  
REMARK 470     VAL A 886    CG1  CG2                                            
REMARK 470     ARG A 888    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU A 889    CG   CD1  CD2                                       
REMARK 470     ASP A 890    CG   OD1  OD2                                       
REMARK 470     ARG A 891    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS A 893    CG   CD   CE   NZ                                   
REMARK 470     SER A 894    OG                                                  
REMARK 470     ILE A 896    CG1  CG2  CD1                                       
REMARK 470     LEU A 897    CG   CD1  CD2                                       
REMARK 470     TYR A 898    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     VAL A 899    CG1  CG2                                            
REMARK 470     LYS A 900    CG   CD   CE   NZ                                   
REMARK 470     SER A 901    OG                                                  
REMARK 470     LEU A 902    CG   CD1  CD2                                       
REMARK 470     LEU A 903    CG   CD1  CD2                                       
REMARK 470     TRP A 904    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP A 904    CZ3  CH2                                            
REMARK 470     THR A 905    OG1  CG2                                            
REMARK 470     GLU A 906    CG   CD   OE1  OE2                                  
REMARK 470     THR A 907    OG1  CG2                                            
REMARK 470     PHE A 908    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     MET A 909    CG   SD   CE                                        
REMARK 470     ASN A 910    CG   OD1  ND2                                       
REMARK 470     LYS A 911    CG   CD   CE   NZ                                   
REMARK 470     GLU A 912    CG   CD   OE1  OE2                                  
REMARK 470     ASN A 913    CG   OD1  ND2                                       
REMARK 470     GLN A 914    CG   CD   OE1  NE2                                  
REMARK 470     ASN A 915    CG   OD1  ND2                                       
REMARK 470     HIS A 916    CG   ND1  CD2  CE1  NE2                             
REMARK 470     SER A 917    OG                                                  
REMARK 470     TYR A 918    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     SER A 919    OG                                                  
REMARK 470     LEU A 920    CG   CD1  CD2                                       
REMARK 470     LYS A 921    CG   CD   CE   NZ                                   
REMARK 470     SER A 922    OG                                                  
REMARK 470     SER A 923    OG                                                  
REMARK 470     SER A 925    OG                                                  
REMARK 470     PHE A 926    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASN A 927    CG   OD1  ND2                                       
REMARK 470     VAL A 928    CG1  CG2                                            
REMARK 470     ILE A 929    CG1  CG2  CD1                                       
REMARK 470     GLU A 930    CG   CD   OE1  OE2                                  
REMARK 470     PHE A 931    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     PRO A 932    CG   CD                                             
REMARK 470     TYR A 933    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LYS A 934    CG   CD   CE   NZ                                   
REMARK 470     ASN A 935    CG   OD1  ND2                                       
REMARK 470     LEU A 936    CG   CD1  CD2                                       
REMARK 470     PRO A 937    CG   CD                                             
REMARK 470     ILE A 938    CG1  CG2  CD1                                       
REMARK 470     GLU A 939    CG   CD   OE1  OE2                                  
REMARK 470     ASP A 940    CG   OD1  OD2                                       
REMARK 470     ILE A 941    CG1  CG2  CD1                                       
REMARK 470     THR A 942    OG1  CG2                                            
REMARK 470     ASN A 943    CG   OD1  ND2                                       
REMARK 470     SER A 944    OG                                                  
REMARK 470     THR A 945    OG1  CG2                                            
REMARK 470     LEU A 946    CG   CD1  CD2                                       
REMARK 470     VAL A 947    CG1  CG2                                            
REMARK 470     THR A 948    OG1  CG2                                            
REMARK 470     THR A 949    OG1  CG2                                            
REMARK 470     ASN A 950    CG   OD1  ND2                                       
REMARK 470     VAL A 951    CG1  CG2                                            
REMARK 470     THR A 952    OG1  CG2                                            
REMARK 470     TRP A 953    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP A 953    CZ3  CH2                                            
REMARK 470     PRO B   2    CG   CD                                             
REMARK 470     ASN B   3    CG   OD1  ND2                                       
REMARK 470     ILE B   4    CG1  CG2  CD1                                       
REMARK 470     CYS B   5    SG                                                  
REMARK 470     THR B   6    OG1  CG2                                            
REMARK 470     THR B   7    OG1  CG2                                            
REMARK 470     ARG B   8    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     VAL B  10    CG1  CG2                                            
REMARK 470     SER B  11    OG                                                  
REMARK 470     SER B  12    OG                                                  
REMARK 470     CYS B  13    SG                                                  
REMARK 470     GLN B  14    CG   CD   OE1  NE2                                  
REMARK 470     GLN B  15    CG   CD   OE1  NE2                                  
REMARK 470     CYS B  16    SG                                                  
REMARK 470     LEU B  17    CG   CD1  CD2                                       
REMARK 470     VAL B  19    CG1  CG2                                            
REMARK 470     SER B  20    OG                                                  
REMARK 470     PRO B  21    CG   CD                                             
REMARK 470     MET B  22    CG   SD   CE                                        
REMARK 470     CYS B  23    SG                                                  
REMARK 470     TRP B  25    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP B  25    CZ3  CH2                                            
REMARK 470     CYS B  26    SG                                                  
REMARK 470     SER B  27    OG                                                  
REMARK 470     ASP B  28    CG   OD1  OD2                                       
REMARK 470     GLU B  29    CG   CD   OE1  OE2                                  
REMARK 470     LEU B  31    CG   CD1  CD2                                       
REMARK 470     PRO B  32    CG   CD                                             
REMARK 470     LEU B  33    CG   CD1  CD2                                       
REMARK 470     SER B  35    OG                                                  
REMARK 470     PRO B  36    CG   CD                                             
REMARK 470     ARG B  37    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     CYS B  38    SG                                                  
REMARK 470     ASP B  39    CG   OD1  OD2                                       
REMARK 470     LEU B  40    CG   CD1  CD2                                       
REMARK 470     LYS B  41    CG   CD   CE   NZ                                   
REMARK 470     GLU B  42    CG   CD   OE1  OE2                                  
REMARK 470     ASN B  43    CG   OD1  ND2                                       
REMARK 470     LEU B  44    CG   CD1  CD2                                       
REMARK 470     LEU B  45    CG   CD1  CD2                                       
REMARK 470     LYS B  46    CG   CD   CE   NZ                                   
REMARK 470     ASP B  47    CG   OD1  OD2                                       
REMARK 470     ASN B  48    CG   OD1  ND2                                       
REMARK 470     CYS B  49    SG                                                  
REMARK 470     PRO B  51    CG   CD                                             
REMARK 470     GLU B  52    CG   CD   OE1  OE2                                  
REMARK 470     SER B  53    OG                                                  
REMARK 470     ILE B  54    CG1  CG2  CD1                                       
REMARK 470     GLU B  55    CG   CD   OE1  OE2                                  
REMARK 470     PHE B  56    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     PRO B  57    CG   CD                                             
REMARK 470     VAL B  58    CG1  CG2                                            
REMARK 470     SER B  59    OG                                                  
REMARK 470     GLU B  60    CG   CD   OE1  OE2                                  
REMARK 470     ARG B  62    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     VAL B  63    CG1  CG2                                            
REMARK 470     LEU B  64    CG   CD1  CD2                                       
REMARK 470     GLU B  65    CG   CD   OE1  OE2                                  
REMARK 470     ASP B  66    CG   OD1  OD2                                       
REMARK 470     ARG B  67    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     PRO B  68    CG   CD                                             
REMARK 470     LEU B  69    CG   CD1  CD2                                       
REMARK 470     SER B  70    OG                                                  
REMARK 470     ASP B  71    CG   OD1  OD2                                       
REMARK 470     LYS B  72    CG   CD   CE   NZ                                   
REMARK 470     SER B  74    OG                                                  
REMARK 470     ASP B  76    CG   OD1  OD2                                       
REMARK 470     SER B  77    OG                                                  
REMARK 470     SER B  78    OG                                                  
REMARK 470     GLN B  79    CG   CD   OE1  NE2                                  
REMARK 470     VAL B  80    CG1  CG2                                            
REMARK 470     THR B  81    OG1  CG2                                            
REMARK 470     GLN B  82    CG   CD   OE1  NE2                                  
REMARK 470     VAL B  83    CG1  CG2                                            
REMARK 470     SER B  84    OG                                                  
REMARK 470     PRO B  85    CG   CD                                             
REMARK 470     GLN B  86    CG   CD   OE1  NE2                                  
REMARK 470     ARG B  87    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ILE B  88    CG1  CG2  CD1                                       
REMARK 470     LEU B  90    CG   CD1  CD2                                       
REMARK 470     ARG B  91    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU B  92    CG   CD1  CD2                                       
REMARK 470     ARG B  93    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     PRO B  94    CG   CD                                             
REMARK 470     ASP B  95    CG   OD1  OD2                                       
REMARK 470     ASP B  96    CG   OD1  OD2                                       
REMARK 470     SER B  97    OG                                                  
REMARK 470     LYS B  98    CG   CD   CE   NZ                                   
REMARK 470     ASN B  99    CG   OD1  ND2                                       
REMARK 470     PHE B 100    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     SER B 101    OG                                                  
REMARK 470     ILE B 102    CG1  CG2  CD1                                       
REMARK 470     GLN B 103    CG   CD   OE1  NE2                                  
REMARK 470     VAL B 104    CG1  CG2                                            
REMARK 470     ARG B 105    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLN B 106    CG   CD   OE1  NE2                                  
REMARK 470     VAL B 107    CG1  CG2                                            
REMARK 470     GLU B 108    CG   CD   OE1  OE2                                  
REMARK 470     ASP B 109    CG   OD1  OD2                                       
REMARK 470     TYR B 110    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     PRO B 111    CG   CD                                             
REMARK 470     VAL B 112    CG1  CG2                                            
REMARK 470     ASP B 113    CG   OD1  OD2                                       
REMARK 470     ILE B 114    CG1  CG2  CD1                                       
REMARK 470     TYR B 115    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     TYR B 116    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LEU B 117    CG   CD1  CD2                                       
REMARK 470     MET B 118    CG   SD   CE                                        
REMARK 470     ASP B 119    CG   OD1  OD2                                       
REMARK 470     LEU B 120    CG   CD1  CD2                                       
REMARK 470     SER B 121    OG                                                  
REMARK 470     TYR B 122    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     SER B 123    OG                                                  
REMARK 470     MET B 124    CG   SD   CE                                        
REMARK 470     LYS B 125    CG   CD   CE   NZ                                   
REMARK 470     ASP B 126    CG   OD1  OD2                                       
REMARK 470     ASP B 127    CG   OD1  OD2                                       
REMARK 470     LEU B 128    CG   CD1  CD2                                       
REMARK 470     TRP B 129    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP B 129    CZ3  CH2                                            
REMARK 470     SER B 130    OG                                                  
REMARK 470     ILE B 131    CG1  CG2  CD1                                       
REMARK 470     GLN B 132    CG   CD   OE1  NE2                                  
REMARK 470     ASN B 133    CG   OD1  ND2                                       
REMARK 470     LEU B 134    CG   CD1  CD2                                       
REMARK 470     THR B 136    OG1  CG2                                            
REMARK 470     LYS B 137    CG   CD   CE   NZ                                   
REMARK 470     LEU B 138    CG   CD1  CD2                                       
REMARK 470     THR B 140    OG1  CG2                                            
REMARK 470     GLN B 141    CG   CD   OE1  NE2                                  
REMARK 470     MET B 142    CG   SD   CE                                        
REMARK 470     ARG B 143    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS B 144    CG   CD   CE   NZ                                   
REMARK 470     LEU B 145    CG   CD1  CD2                                       
REMARK 470     THR B 146    OG1  CG2                                            
REMARK 470     SER B 147    OG                                                  
REMARK 470     ASN B 148    CG   OD1  ND2                                       
REMARK 470     LEU B 149    CG   CD1  CD2                                       
REMARK 470     ARG B 150    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ILE B 151    CG1  CG2  CD1                                       
REMARK 470     PHE B 153    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     PHE B 156    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     VAL B 157    CG1  CG2                                            
REMARK 470     ASP B 158    CG   OD1  OD2                                       
REMARK 470     LYS B 159    CG   CD   CE   NZ                                   
REMARK 470     PRO B 160    CG   CD                                             
REMARK 470     VAL B 161    CG1  CG2                                            
REMARK 470     SER B 162    OG                                                  
REMARK 470     PRO B 163    CG   CD                                             
REMARK 470     TYR B 164    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     MET B 165    CG   SD   CE                                        
REMARK 470     TYR B 166    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ILE B 167    CG1  CG2  CD1                                       
REMARK 470     SER B 168    OG                                                  
REMARK 470     PRO B 169    CG   CD                                             
REMARK 470     PRO B 170    CG   CD                                             
REMARK 470     GLU B 171    CG   CD   OE1  OE2                                  
REMARK 470     LEU B 173    CG   CD1  CD2                                       
REMARK 470     GLU B 174    CG   CD   OE1  OE2                                  
REMARK 470     ASN B 175    CG   OD1  ND2                                       
REMARK 470     PRO B 176    CG   CD                                             
REMARK 470     CYS B 177    SG                                                  
REMARK 470     TYR B 178    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ASP B 179    CG   OD1  OD2                                       
REMARK 470     MET B 180    CG   SD   CE                                        
REMARK 470     LYS B 181    CG   CD   CE   NZ                                   
REMARK 470     THR B 182    OG1  CG2                                            
REMARK 470     THR B 183    OG1  CG2                                            
REMARK 470     CYS B 184    SG                                                  
REMARK 470     LEU B 185    CG   CD1  CD2                                       
REMARK 470     PRO B 186    CG   CD                                             
REMARK 470     MET B 187    CG   SD   CE                                        
REMARK 470     PHE B 188    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     TYR B 190    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LYS B 191    CG   CD   CE   NZ                                   
REMARK 470     HIS B 192    CG   ND1  CD2  CE1  NE2                             
REMARK 470     VAL B 193    CG1  CG2                                            
REMARK 470     LEU B 194    CG   CD1  CD2                                       
REMARK 470     THR B 195    OG1  CG2                                            
REMARK 470     LEU B 196    CG   CD1  CD2                                       
REMARK 470     THR B 197    OG1  CG2                                            
REMARK 470     ASP B 198    CG   OD1  OD2                                       
REMARK 470     GLN B 199    CG   CD   OE1  NE2                                  
REMARK 470     VAL B 200    CG1  CG2                                            
REMARK 470     THR B 201    OG1  CG2                                            
REMARK 470     ARG B 202    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     PHE B 203    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASN B 204    CG   OD1  ND2                                       
REMARK 470     GLU B 205    CG   CD   OE1  OE2                                  
REMARK 470     GLU B 206    CG   CD   OE1  OE2                                  
REMARK 470     VAL B 207    CG1  CG2                                            
REMARK 470     LYS B 208    CG   CD   CE   NZ                                   
REMARK 470     LYS B 209    CG   CD   CE   NZ                                   
REMARK 470     GLN B 210    CG   CD   OE1  NE2                                  
REMARK 470     SER B 211    OG                                                  
REMARK 470     VAL B 212    CG1  CG2                                            
REMARK 470     SER B 213    OG                                                  
REMARK 470     ARG B 214    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASN B 215    CG   OD1  ND2                                       
REMARK 470     ARG B 216    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP B 217    CG   OD1  OD2                                       
REMARK 470     PRO B 219    CG   CD                                             
REMARK 470     GLU B 220    CG   CD   OE1  OE2                                  
REMARK 470     PHE B 223    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASP B 224    CG   OD1  OD2                                       
REMARK 470     ILE B 226    CG1  CG2  CD1                                       
REMARK 470     MET B 227    CG   SD   CE                                        
REMARK 470     GLN B 228    CG   CD   OE1  NE2                                  
REMARK 470     THR B 230    OG1  CG2                                            
REMARK 470     VAL B 231    CG1  CG2                                            
REMARK 470     CYS B 232    SG                                                  
REMARK 470     ASP B 233    CG   OD1  OD2                                       
REMARK 470     GLU B 234    CG   CD   OE1  OE2                                  
REMARK 470     LYS B 235    CG   CD   CE   NZ                                   
REMARK 470     ILE B 236    CG1  CG2  CD1                                       
REMARK 470     TRP B 238    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP B 238    CZ3  CH2                                            
REMARK 470     ARG B 239    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASN B 240    CG   OD1  ND2                                       
REMARK 470     ASP B 241    CG   OD1  OD2                                       
REMARK 470     SER B 243    OG                                                  
REMARK 470     HIS B 244    CG   ND1  CD2  CE1  NE2                             
REMARK 470     LEU B 245    CG   CD1  CD2                                       
REMARK 470     LEU B 246    CG   CD1  CD2                                       
REMARK 470     VAL B 247    CG1  CG2                                            
REMARK 470     PHE B 248    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     THR B 249    OG1  CG2                                            
REMARK 470     THR B 250    OG1  CG2                                            
REMARK 470     ASP B 251    CG   OD1  OD2                                       
REMARK 470     LYS B 253    CG   CD   CE   NZ                                   
REMARK 470     THR B 254    OG1  CG2                                            
REMARK 470     HIS B 255    CG   ND1  CD2  CE1  NE2                             
REMARK 470     ILE B 256    CG1  CG2  CD1                                       
REMARK 470     LEU B 258    CG   CD1  CD2                                       
REMARK 470     ASP B 259    CG   OD1  OD2                                       
REMARK 470     ARG B 261    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU B 262    CG   CD1  CD2                                       
REMARK 470     ILE B 265    CG1  CG2  CD1                                       
REMARK 470     VAL B 266    CG1  CG2                                            
REMARK 470     GLN B 267    CG   CD   OE1  NE2                                  
REMARK 470     PRO B 268    CG   CD                                             
REMARK 470     ASN B 269    CG   OD1  ND2                                       
REMARK 470     ASP B 270    CG   OD1  OD2                                       
REMARK 470     GLN B 272    CG   CD   OE1  NE2                                  
REMARK 470     CYS B 273    SG                                                  
REMARK 470     HIS B 274    CG   ND1  CD2  CE1  NE2                             
REMARK 470     VAL B 275    CG1  CG2                                            
REMARK 470     SER B 277    OG                                                  
REMARK 470     ASP B 278    CG   OD1  OD2                                       
REMARK 470     ASN B 279    CG   OD1  ND2                                       
REMARK 470     HIS B 280    CG   ND1  CD2  CE1  NE2                             
REMARK 470     TYR B 281    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     SER B 282    OG                                                  
REMARK 470     SER B 284    OG                                                  
REMARK 470     THR B 285    OG1  CG2                                            
REMARK 470     THR B 286    OG1  CG2                                            
REMARK 470     MET B 287    CG   SD   CE                                        
REMARK 470     ASP B 288    CG   OD1  OD2                                       
REMARK 470     TYR B 289    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     PRO B 290    CG   CD                                             
REMARK 470     SER B 291    OG                                                  
REMARK 470     LEU B 292    CG   CD1  CD2                                       
REMARK 470     LEU B 294    CG   CD1  CD2                                       
REMARK 470     MET B 295    CG   SD   CE                                        
REMARK 470     THR B 296    OG1  CG2                                            
REMARK 470     GLU B 297    CG   CD   OE1  OE2                                  
REMARK 470     LYS B 298    CG   CD   CE   NZ                                   
REMARK 470     LEU B 299    CG   CD1  CD2                                       
REMARK 470     SER B 300    OG                                                  
REMARK 470     GLN B 301    CG   CD   OE1  NE2                                  
REMARK 470     LYS B 302    CG   CD   CE   NZ                                   
REMARK 470     ASN B 303    CG   OD1  ND2                                       
REMARK 470     ILE B 304    CG1  CG2  CD1                                       
REMARK 470     ASN B 305    CG   OD1  ND2                                       
REMARK 470     LEU B 306    CG   CD1  CD2                                       
REMARK 470     ILE B 307    CG1  CG2  CD1                                       
REMARK 470     PHE B 308    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     VAL B 310    CG1  CG2                                            
REMARK 470     THR B 311    OG1  CG2                                            
REMARK 470     GLU B 312    CG   CD   OE1  OE2                                  
REMARK 470     ASN B 313    CG   OD1  ND2                                       
REMARK 470     VAL B 314    CG1  CG2                                            
REMARK 470     VAL B 315    CG1  CG2                                            
REMARK 470     ASN B 316    CG   OD1  ND2                                       
REMARK 470     LEU B 317    CG   CD1  CD2                                       
REMARK 470     TYR B 318    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     GLN B 319    CG   CD   OE1  NE2                                  
REMARK 470     ASN B 320    CG   OD1  ND2                                       
REMARK 470     TYR B 321    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     SER B 322    OG                                                  
REMARK 470     GLU B 323    CG   CD   OE1  OE2                                  
REMARK 470     LEU B 324    CG   CD1  CD2                                       
REMARK 470     ILE B 325    CG1  CG2  CD1                                       
REMARK 470     PRO B 326    CG   CD                                             
REMARK 470     THR B 328    OG1  CG2                                            
REMARK 470     THR B 329    OG1  CG2                                            
REMARK 470     VAL B 330    CG1  CG2                                            
REMARK 470     VAL B 332    CG1  CG2                                            
REMARK 470     LEU B 333    CG   CD1  CD2                                       
REMARK 470     SER B 334    OG                                                  
REMARK 470     MET B 335    CG   SD   CE                                        
REMARK 470     ASP B 336    CG   OD1  OD2                                       
REMARK 470     SER B 337    OG                                                  
REMARK 470     SER B 338    OG                                                  
REMARK 470     ASN B 339    CG   OD1  ND2                                       
REMARK 470     VAL B 340    CG1  CG2                                            
REMARK 470     LEU B 341    CG   CD1  CD2                                       
REMARK 470     GLN B 342    CG   CD   OE1  NE2                                  
REMARK 470     LEU B 343    CG   CD1  CD2                                       
REMARK 470     ILE B 344    CG1  CG2  CD1                                       
REMARK 470     VAL B 345    CG1  CG2                                            
REMARK 470     ASP B 346    CG   OD1  OD2                                       
REMARK 470     TYR B 348    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LYS B 350    CG   CD   CE   NZ                                   
REMARK 470     ILE B 351    CG1  CG2  CD1                                       
REMARK 470     ARG B 352    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     SER B 353    OG                                                  
REMARK 470     LYS B 354    CG   CD   CE   NZ                                   
REMARK 470     VAL B 355    CG1  CG2                                            
REMARK 470     GLU B 356    CG   CD   OE1  OE2                                  
REMARK 470     LEU B 357    CG   CD1  CD2                                       
REMARK 470     GLU B 358    CG   CD   OE1  OE2                                  
REMARK 470     VAL B 359    CG1  CG2                                            
REMARK 470     ARG B 360    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP B 361    CG   OD1  OD2                                       
REMARK 470     LEU B 362    CG   CD1  CD2                                       
REMARK 470     PRO B 363    CG   CD                                             
REMARK 470     GLU B 364    CG   CD   OE1  OE2                                  
REMARK 470     GLU B 365    CG   CD   OE1  OE2                                  
REMARK 470     LEU B 366    CG   CD1  CD2                                       
REMARK 470     SER B 367    OG                                                  
REMARK 470     LEU B 368    CG   CD1  CD2                                       
REMARK 470     SER B 369    OG                                                  
REMARK 470     PHE B 370    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASN B 371    CG   OD1  ND2                                       
REMARK 470     THR B 373    OG1  CG2                                            
REMARK 470     CYS B 374    SG                                                  
REMARK 470     LEU B 375    CG   CD1  CD2                                       
REMARK 470     ASN B 376    CG   OD1  ND2                                       
REMARK 470     ASN B 377    CG   OD1  ND2                                       
REMARK 470     GLU B 378    CG   CD   OE1  OE2                                  
REMARK 470     VAL B 379    CG1  CG2                                            
REMARK 470     ILE B 380    CG1  CG2  CD1                                       
REMARK 470     PRO B 381    CG   CD                                             
REMARK 470     LEU B 383    CG   CD1  CD2                                       
REMARK 470     LYS B 384    CG   CD   CE   NZ                                   
REMARK 470     SER B 385    OG                                                  
REMARK 470     CYS B 386    SG                                                  
REMARK 470     MET B 387    CG   SD   CE                                        
REMARK 470     LEU B 389    CG   CD1  CD2                                       
REMARK 470     LYS B 390    CG   CD   CE   NZ                                   
REMARK 470     ILE B 391    CG1  CG2  CD1                                       
REMARK 470     ASP B 393    CG   OD1  OD2                                       
REMARK 470     THR B 394    OG1  CG2                                            
REMARK 470     VAL B 395    CG1  CG2                                            
REMARK 470     SER B 396    OG                                                  
REMARK 470     PHE B 397    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     SER B 398    OG                                                  
REMARK 470     ILE B 399    CG1  CG2  CD1                                       
REMARK 470     GLU B 400    CG   CD   OE1  OE2                                  
REMARK 470     LYS B 402    CG   CD   CE   NZ                                   
REMARK 470     VAL B 403    CG1  CG2                                            
REMARK 470     ARG B 404    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     CYS B 406    SG                                                  
REMARK 470     PRO B 407    CG   CD                                             
REMARK 470     GLN B 408    CG   CD   OE1  NE2                                  
REMARK 470     GLU B 409    CG   CD   OE1  OE2                                  
REMARK 470     LYS B 410    CG   CD   CE   NZ                                   
REMARK 470     GLU B 411    CG   CD   OE1  OE2                                  
REMARK 470     LYS B 412    CG   CD   CE   NZ                                   
REMARK 470     SER B 413    OG                                                  
REMARK 470     PHE B 414    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     THR B 415    OG1  CG2                                            
REMARK 470     ILE B 416    CG1  CG2  CD1                                       
REMARK 470     LYS B 417    CG   CD   CE   NZ                                   
REMARK 470     PRO B 418    CG   CD                                             
REMARK 470     VAL B 419    CG1  CG2                                            
REMARK 470     PHE B 421    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     LYS B 422    CG   CD   CE   NZ                                   
REMARK 470     ASP B 423    CG   OD1  OD2                                       
REMARK 470     SER B 424    OG                                                  
REMARK 470     LEU B 425    CG   CD1  CD2                                       
REMARK 470     ILE B 426    CG1  CG2  CD1                                       
REMARK 470     VAL B 427    CG1  CG2                                            
REMARK 470     GLN B 428    CG   CD   OE1  NE2                                  
REMARK 470     VAL B 429    CG1  CG2                                            
REMARK 470     THR B 430    OG1  CG2                                            
REMARK 470     PHE B 431    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASP B 432    CG   OD1  OD2                                       
REMARK 470     CYS B 433    SG                                                  
REMARK 470     ASP B 434    CG   OD1  OD2                                       
REMARK 470     CYS B 435    SG                                                  
REMARK 470     CYS B 437    SG                                                  
REMARK 470     GLN B 438    CG   CD   OE1  NE2                                  
REMARK 470     GLN B 440    CG   CD   OE1  NE2                                  
REMARK 470     GLU B 442    CG   CD   OE1  OE2                                  
REMARK 470     PRO B 443    CG   CD                                             
REMARK 470     ASN B 444    CG   OD1  ND2                                       
REMARK 470     SER B 445    OG                                                  
REMARK 470     HIS B 446    CG   ND1  CD2  CE1  NE2                             
REMARK 470     ARG B 447    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     CYS B 448    SG                                                  
REMARK 470     ASN B 449    CG   OD1  ND2                                       
REMARK 470     ASN B 450    CG   OD1  ND2                                       
REMARK 470     ASN B 452    CG   OD1  ND2                                       
REMARK 470     THR B 454    OG1  CG2                                            
REMARK 470     PHE B 455    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLU B 456    CG   CD   OE1  OE2                                  
REMARK 470     CYS B 457    SG                                                  
REMARK 470     VAL B 459    CG1  CG2                                            
REMARK 470     CYS B 460    SG                                                  
REMARK 470     ARG B 461    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     CYS B 462    SG                                                  
REMARK 470     PRO B 464    CG   CD                                             
REMARK 470     TRP B 466    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP B 466    CZ3  CH2                                            
REMARK 470     LEU B 467    CG   CD1  CD2                                       
REMARK 470     SER B 469    OG                                                  
REMARK 470     GLN B 470    CG   CD   OE1  NE2                                  
REMARK 470     CYS B 471    SG                                                  
REMARK 470     GLU B 472    CG   CD   OE1  OE2                                  
REMARK 470     CYS B 473    SG                                                  
REMARK 470     SER B 474    OG                                                  
REMARK 470     GLU B 475    CG   CD   OE1  OE2                                  
REMARK 470     GLU B 476    CG   CD   OE1  OE2                                  
REMARK 470     ASP B 477    CG   OD1  OD2                                       
REMARK 470     TYR B 478    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ARG B 479    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     PRO B 480    CG   CD                                             
REMARK 470     SER B 481    OG                                                  
REMARK 470     GLN B 482    CG   CD   OE1  NE2                                  
REMARK 470     GLN B 483    CG   CD   OE1  NE2                                  
REMARK 470     ASP B 484    CG   OD1  OD2                                       
REMARK 470     GLU B 485    CG   CD   OE1  OE2                                  
REMARK 470     CYS B 486    SG                                                  
REMARK 470     SER B 487    OG                                                  
REMARK 470     PRO B 488    CG   CD                                             
REMARK 470     ARG B 489    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU B 490    CG   CD   OE1  OE2                                  
REMARK 470     GLN B 492    CG   CD   OE1  NE2                                  
REMARK 470     PRO B 493    CG   CD                                             
REMARK 470     VAL B 494    CG1  CG2                                            
REMARK 470     CYS B 495    SG                                                  
REMARK 470     SER B 496    OG                                                  
REMARK 470     GLN B 497    CG   CD   OE1  NE2                                  
REMARK 470     ARG B 498    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU B 500    CG   CD   OE1  OE2                                  
REMARK 470     CYS B 501    SG                                                  
REMARK 470     LEU B 502    CG   CD1  CD2                                       
REMARK 470     CYS B 503    SG                                                  
REMARK 470     GLN B 505    CG   CD   OE1  NE2                                  
REMARK 470     CYS B 506    SG                                                  
REMARK 470     VAL B 507    CG1  CG2                                            
REMARK 470     CYS B 508    SG                                                  
REMARK 470     HIS B 509    CG   ND1  CD2  CE1  NE2                             
REMARK 470     SER B 510    OG                                                  
REMARK 470     SER B 511    OG                                                  
REMARK 470     ASP B 512    CG   OD1  OD2                                       
REMARK 470     PHE B 513    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     LYS B 515    CG   CD   CE   NZ                                   
REMARK 470     ILE B 516    CG1  CG2  CD1                                       
REMARK 470     THR B 517    OG1  CG2                                            
REMARK 470     LYS B 519    CG   CD   CE   NZ                                   
REMARK 470     TYR B 520    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     CYS B 521    SG                                                  
REMARK 470     GLU B 522    CG   CD   OE1  OE2                                  
REMARK 470     CYS B 523    SG                                                  
REMARK 470     ASP B 524    CG   OD1  OD2                                       
REMARK 470     ASP B 525    CG   OD1  OD2                                       
REMARK 470     PHE B 526    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     SER B 527    OG                                                  
REMARK 470     CYS B 528    SG                                                  
REMARK 470     VAL B 529    CG1  CG2                                            
REMARK 470     ARG B 530    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     TYR B 531    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LYS B 532    CG   CD   CE   NZ                                   
REMARK 470     GLU B 534    CG   CD   OE1  OE2                                  
REMARK 470     MET B 535    CG   SD   CE                                        
REMARK 470     CYS B 536    SG                                                  
REMARK 470     SER B 537    OG                                                  
REMARK 470     HIS B 539    CG   ND1  CD2  CE1  NE2                             
REMARK 470     GLN B 541    CG   CD   OE1  NE2                                  
REMARK 470     CYS B 542    SG                                                  
REMARK 470     SER B 543    OG                                                  
REMARK 470     CYS B 544    SG                                                  
REMARK 470     ASP B 546    CG   OD1  OD2                                       
REMARK 470     CYS B 547    SG                                                  
REMARK 470     LEU B 548    CG   CD1  CD2                                       
REMARK 470     CYS B 549    SG                                                  
REMARK 470     ASP B 550    CG   OD1  OD2                                       
REMARK 470     SER B 551    OG                                                  
REMARK 470     ASP B 552    CG   OD1  OD2                                       
REMARK 470     TRP B 553    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP B 553    CZ3  CH2                                            
REMARK 470     THR B 554    OG1  CG2                                            
REMARK 470     TYR B 556    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     TYR B 557    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     CYS B 558    SG                                                  
REMARK 470     ASN B 559    CG   OD1  ND2                                       
REMARK 470     CYS B 560    SG                                                  
REMARK 470     THR B 561    OG1  CG2                                            
REMARK 470     THR B 562    OG1  CG2                                            
REMARK 470     ARG B 563    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     THR B 564    OG1  CG2                                            
REMARK 470     ASP B 565    CG   OD1  OD2                                       
REMARK 470     THR B 566    OG1  CG2                                            
REMARK 470     CYS B 567    SG                                                  
REMARK 470     MET B 568    CG   SD   CE                                        
REMARK 470     SER B 569    OG                                                  
REMARK 470     SER B 570    OG                                                  
REMARK 470     ASN B 571    CG   OD1  ND2                                       
REMARK 470     LEU B 573    CG   CD1  CD2                                       
REMARK 470     LEU B 574    CG   CD1  CD2                                       
REMARK 470     CYS B 575    SG                                                  
REMARK 470     SER B 576    OG                                                  
REMARK 470     ARG B 578    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS B 580    CG   CD   CE   NZ                                   
REMARK 470     CYS B 581    SG                                                  
REMARK 470     GLU B 582    CG   CD   OE1  OE2                                  
REMARK 470     CYS B 583    SG                                                  
REMARK 470     SER B 585    OG                                                  
REMARK 470     CYS B 586    SG                                                  
REMARK 470     VAL B 587    CG1  CG2                                            
REMARK 470     CYS B 588    SG                                                  
REMARK 470     ILE B 589    CG1  CG2  CD1                                       
REMARK 470     GLN B 590    CG   CD   OE1  NE2                                  
REMARK 470     PRO B 591    CG   CD                                             
REMARK 470     SER B 593    OG                                                  
REMARK 470     TYR B 594    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ASP B 596    CG   OD1  OD2                                       
REMARK 470     THR B 597    OG1  CG2                                            
REMARK 470     CYS B 598    SG                                                  
REMARK 470     GLU B 599    CG   CD   OE1  OE2                                  
REMARK 470     LYS B 600    CG   CD   CE   NZ                                   
REMARK 470     CYS B 601    SG                                                  
REMARK 470     PRO B 602    CG   CD                                             
REMARK 470     THR B 603    OG1  CG2                                            
REMARK 470     CYS B 604    SG                                                  
REMARK 470     PRO B 605    CG   CD                                             
REMARK 470     ASP B 606    CG   OD1  OD2                                       
REMARK 470     CYS B 608    SG                                                  
REMARK 470     THR B 609    OG1  CG2                                            
REMARK 470     PHE B 610    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     LYS B 611    CG   CD   CE   NZ                                   
REMARK 470     LYS B 612    CG   CD   CE   NZ                                   
REMARK 470     GLU B 613    CG   CD   OE1  OE2                                  
REMARK 470     CYS B 614    SG                                                  
REMARK 470     VAL B 615    CG1  CG2                                            
REMARK 470     GLU B 616    CG   CD   OE1  OE2                                  
REMARK 470     CYS B 617    SG                                                  
REMARK 470     LYS B 618    CG   CD   CE   NZ                                   
REMARK 470     LYS B 619    CG   CD   CE   NZ                                   
REMARK 470     PHE B 620    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASP B 621    CG   OD1  OD2                                       
REMARK 470     ARG B 622    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU B 625    CG   CD1  CD2                                       
REMARK 470     HIS B 626    CG   ND1  CD2  CE1  NE2                             
REMARK 470     ASP B 627    CG   OD1  OD2                                       
REMARK 470     GLU B 628    CG   CD   OE1  OE2                                  
REMARK 470     ASN B 629    CG   OD1  ND2                                       
REMARK 470     THR B 630    OG1  CG2                                            
REMARK 470     CYS B 631    SG                                                  
REMARK 470     ASN B 632    CG   OD1  ND2                                       
REMARK 470     ARG B 633    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     TYR B 634    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     CYS B 635    SG                                                  
REMARK 470     ARG B 636    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP B 637    CG   OD1  OD2                                       
REMARK 470     GLU B 638    CG   CD   OE1  OE2                                  
REMARK 470     ILE B 639    CG1  CG2  CD1                                       
REMARK 470     GLU B 640    CG   CD   OE1  OE2                                  
REMARK 470     SER B 641    OG                                                  
REMARK 470     VAL B 642    CG1  CG2                                            
REMARK 470     LYS B 643    CG   CD   CE   NZ                                   
REMARK 470     GLU B 644    CG   CD   OE1  OE2                                  
REMARK 470     LEU B 645    CG   CD1  CD2                                       
REMARK 470     LYS B 646    CG   CD   CE   NZ                                   
REMARK 470     ASP B 647    CG   OD1  OD2                                       
REMARK 470     THR B 648    OG1  CG2                                            
REMARK 470     LYS B 650    CG   CD   CE   NZ                                   
REMARK 470     ASP B 651    CG   OD1  OD2                                       
REMARK 470     VAL B 653    CG1  CG2                                            
REMARK 470     ASN B 654    CG   OD1  ND2                                       
REMARK 470     CYS B 655    SG                                                  
REMARK 470     THR B 656    OG1  CG2                                            
REMARK 470     TYR B 657    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LYS B 658    CG   CD   CE   NZ                                   
REMARK 470     ASN B 659    CG   OD1  ND2                                       
REMARK 470     GLU B 660    CG   CD   OE1  OE2                                  
REMARK 470     ASP B 661    CG   OD1  OD2                                       
REMARK 470     ASP B 662    CG   OD1  OD2                                       
REMARK 470     CYS B 663    SG                                                  
REMARK 470     VAL B 664    CG1  CG2                                            
REMARK 470     VAL B 665    CG1  CG2                                            
REMARK 470     ARG B 666    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     PHE B 667    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLN B 668    CG   CD   OE1  NE2                                  
REMARK 470     TYR B 669    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     TYR B 670    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     GLU B 671    CG   CD   OE1  OE2                                  
REMARK 470     ASP B 672    CG   OD1  OD2                                       
REMARK 470     SER B 673    OG                                                  
REMARK 470     SER B 674    OG                                                  
REMARK 470     LYS B 676    CG   CD   CE   NZ                                   
REMARK 470     SER B 677    OG                                                  
REMARK 470     ILE B 678    CG1  CG2  CD1                                       
REMARK 470     LEU B 679    CG   CD1  CD2                                       
REMARK 470     TYR B 680    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     VAL B 681    CG1  CG2                                            
REMARK 470     VAL B 682    CG1  CG2                                            
REMARK 470     GLU B 683    CG   CD   OE1  OE2                                  
REMARK 470     GLU B 684    CG   CD   OE1  OE2                                  
REMARK 470     PRO B 685    CG   CD                                             
REMARK 470     GLU H   1    CG   CD   OE1  OE2                                  
REMARK 470     VAL H   2    CG1  CG2                                            
REMARK 470     GLN H   3    CG   CD   OE1  NE2                                  
REMARK 470     LEU H   4    CG   CD1  CD2                                       
REMARK 470     GLU H   5    CG   CD   OE1  OE2                                  
REMARK 470     GLU H   6    CG   CD   OE1  OE2                                  
REMARK 470     SER H   7    OG                                                  
REMARK 470     LEU H  11    CG   CD1  CD2                                       
REMARK 470     VAL H  12    CG1  CG2                                            
REMARK 470     LYS H  13    CG   CD   CE   NZ                                   
REMARK 470     PRO H  14    CG   CD                                             
REMARK 470     SER H  17    OG                                                  
REMARK 470     LEU H  18    CG   CD1  CD2                                       
REMARK 470     LYS H  19    CG   CD   CE   NZ                                   
REMARK 470     LEU H  20    CG   CD1  CD2                                       
REMARK 470     SER H  21    OG                                                  
REMARK 470     CYS H  22    SG                                                  
REMARK 470     SER H  25    OG                                                  
REMARK 470     PHE H  27    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     PHE H  29    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     SER H  30    OG                                                  
REMARK 470     SER H  31    OG                                                  
REMARK 470     TYR H  32    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     ASP H  33    CG   OD1  OD2                                       
REMARK 470     MET H  34    CG   SD   CE                                        
REMARK 470     SER H  35    OG                                                  
REMARK 470     TRP H  36    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP H  36    CZ3  CH2                                            
REMARK 470     VAL H  37    CG1  CG2                                            
REMARK 470     ARG H  38    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLN H  39    CG   CD   OE1  NE2                                  
REMARK 470     ILE H  40    CG1  CG2  CD1                                       
REMARK 470     PRO H  41    CG   CD                                             
REMARK 470     GLU H  42    CG   CD   OE1  OE2                                  
REMARK 470     LYS H  43    CG   CD   CE   NZ                                   
REMARK 470     ARG H  44    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU H  45    CG   CD1  CD2                                       
REMARK 470     GLU H  46    CG   CD   OE1  OE2                                  
REMARK 470     TRP H  47    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP H  47    CZ3  CH2                                            
REMARK 470     VAL H  48    CG1  CG2                                            
REMARK 470     LYS H  50    CG   CD   CE   NZ                                   
REMARK 470     VAL H  51    CG1  CG2                                            
REMARK 470     SER H  52    OG                                                  
REMARK 470     SER H  53    OG                                                  
REMARK 470     SER H  57    OG                                                  
REMARK 470     THR H  58    OG1  CG2                                            
REMARK 470     TYR H  59    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     TYR H  60    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LEU H  61    CG   CD1  CD2                                       
REMARK 470     ASP H  62    CG   OD1  OD2                                       
REMARK 470     THR H  63    OG1  CG2                                            
REMARK 470     VAL H  64    CG1  CG2                                            
REMARK 470     GLN H  65    CG   CD   OE1  NE2                                  
REMARK 470     ARG H  67    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     PHE H  68    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     THR H  69    OG1  CG2                                            
REMARK 470     ILE H  70    CG1  CG2  CD1                                       
REMARK 470     SER H  71    OG                                                  
REMARK 470     ARG H  72    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP H  73    CG   OD1  OD2                                       
REMARK 470     ASN H  74    CG   OD1  ND2                                       
REMARK 470     LYS H  76    CG   CD   CE   NZ                                   
REMARK 470     ASN H  77    CG   OD1  ND2                                       
REMARK 470     THR H  78    OG1  CG2                                            
REMARK 470     LEU H  79    CG   CD1  CD2                                       
REMARK 470     TYR H  80    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LEU H  81    CG   CD1  CD2                                       
REMARK 470     GLN H  82    CG   CD   OE1  NE2                                  
REMARK 470     MET H  83    CG   SD   CE                                        
REMARK 470     SER H  84    OG                                                  
REMARK 470     SER H  85    OG                                                  
REMARK 470     LEU H  86    CG   CD1  CD2                                       
REMARK 470     ASN H  87    CG   OD1  ND2                                       
REMARK 470     SER H  88    OG                                                  
REMARK 470     GLU H  89    CG   CD   OE1  OE2                                  
REMARK 470     ASP H  90    CG   OD1  OD2                                       
REMARK 470     THR H  91    OG1  CG2                                            
REMARK 470     MET H  93    CG   SD   CE                                        
REMARK 470     TYR H  94    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     TYR H  95    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     CYS H  96    SG                                                  
REMARK 470     ARG H  98    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     HIS H  99    CG   ND1  CD2  CE1  NE2                             
REMARK 470     ASN H 100    CG   OD1  ND2                                       
REMARK 470     TYR H 101    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     SER H 103    OG                                                  
REMARK 470     PHE H 104    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     TYR H 106    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     TRP H 107    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP H 107    CZ3  CH2                                            
REMARK 470     GLN H 109    CG   CD   OE1  NE2                                  
REMARK 470     THR H 111    OG1  CG2                                            
REMARK 470     LEU H 112    CG   CD1  CD2                                       
REMARK 470     VAL H 113    CG1  CG2                                            
REMARK 470     THR H 114    OG1  CG2                                            
REMARK 470     VAL H 115    CG1  CG2                                            
REMARK 470     SER H 116    OG                                                  
REMARK 470     LYS H 119    CG   CD   CE   NZ                                   
REMARK 470     THR H 120    OG1  CG2                                            
REMARK 470     THR H 121    OG1  CG2                                            
REMARK 470     PRO H 122    CG   CD                                             
REMARK 470     PRO H 123    CG   CD                                             
REMARK 470     SER H 124    OG                                                  
REMARK 470     VAL H 125    CG1  CG2                                            
REMARK 470     TYR H 126    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     PRO H 127    CG   CD                                             
REMARK 470     LEU H 128    CG   CD1  CD2                                       
REMARK 470     PRO H 130    CG   CD                                             
REMARK 470     SER H 132    OG                                                  
REMARK 470     THR H 136    OG1  CG2                                            
REMARK 470     ASN H 137    CG   OD1  ND2                                       
REMARK 470     SER H 138    OG                                                  
REMARK 470     MET H 139    CG   SD   CE                                        
REMARK 470     VAL H 140    CG1  CG2                                            
REMARK 470     THR H 141    OG1  CG2                                            
REMARK 470     LEU H 142    CG   CD1  CD2                                       
REMARK 470     CYS H 144    SG                                                  
REMARK 470     LEU H 145    CG   CD1  CD2                                       
REMARK 470     VAL H 146    CG1  CG2                                            
REMARK 470     LYS H 147    CG   CD   CE   NZ                                   
REMARK 470     TYR H 149    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     PHE H 150    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     PRO H 151    CG   CD                                             
REMARK 470     GLU H 152    CG   CD   OE1  OE2                                  
REMARK 470     PRO H 153    CG   CD                                             
REMARK 470     VAL H 154    CG1  CG2                                            
REMARK 470     THR H 155    OG1  CG2                                            
REMARK 470     VAL H 156    CG1  CG2                                            
REMARK 470     THR H 157    OG1  CG2                                            
REMARK 470     TRP H 158    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP H 158    CZ3  CH2                                            
REMARK 470     ASN H 159    CG   OD1  ND2                                       
REMARK 470     SER H 160    OG                                                  
REMARK 470     SER H 162    OG                                                  
REMARK 470     LEU H 163    CG   CD1  CD2                                       
REMARK 470     SER H 164    OG                                                  
REMARK 470     SER H 165    OG                                                  
REMARK 470     VAL H 167    CG1  CG2                                            
REMARK 470     HIS H 168    CG   ND1  CD2  CE1  NE2                             
REMARK 470     THR H 169    OG1  CG2                                            
REMARK 470     PHE H 170    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     PRO H 171    CG   CD                                             
REMARK 470     VAL H 173    CG1  CG2                                            
REMARK 470     LEU H 174    CG   CD1  CD2                                       
REMARK 470     GLN H 175    CG   CD   OE1  NE2                                  
REMARK 470     SER H 176    OG                                                  
REMARK 470     ASP H 177    CG   OD1  OD2                                       
REMARK 470     LEU H 178    CG   CD1  CD2                                       
REMARK 470     TYR H 179    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     THR H 180    OG1  CG2                                            
REMARK 470     LEU H 181    CG   CD1  CD2                                       
REMARK 470     SER H 182    OG                                                  
REMARK 470     SER H 183    OG                                                  
REMARK 470     SER H 184    OG                                                  
REMARK 470     VAL H 185    CG1  CG2                                            
REMARK 470     THR H 186    OG1  CG2                                            
REMARK 470     VAL H 187    CG1  CG2                                            
REMARK 470     PRO H 188    CG   CD                                             
REMARK 470     SER H 189    OG                                                  
REMARK 470     SER H 190    OG                                                  
REMARK 470     THR H 191    OG1  CG2                                            
REMARK 470     TRP H 192    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP H 192    CZ3  CH2                                            
REMARK 470     PRO H 193    CG   CD                                             
REMARK 470     SER H 194    OG                                                  
REMARK 470     GLU H 195    CG   CD   OE1  OE2                                  
REMARK 470     THR H 196    OG1  CG2                                            
REMARK 470     VAL H 197    CG1  CG2                                            
REMARK 470     THR H 198    OG1  CG2                                            
REMARK 470     CYS H 199    SG                                                  
REMARK 470     ASN H 200    CG   OD1  ND2                                       
REMARK 470     VAL H 201    CG1  CG2                                            
REMARK 470     HIS H 203    CG   ND1  CD2  CE1  NE2                             
REMARK 470     PRO H 204    CG   CD                                             
REMARK 470     SER H 206    OG                                                  
REMARK 470     SER H 207    OG                                                  
REMARK 470     THR H 208    OG1  CG2                                            
REMARK 470     LYS H 209    CG   CD   CE   NZ                                   
REMARK 470     VAL H 210    CG1  CG2                                            
REMARK 470     ASP H 211    CG   OD1  OD2                                       
REMARK 470     LYS H 212    CG   CD   CE   NZ                                   
REMARK 470     LYS H 213    CG   CD   CE   NZ                                   
REMARK 470     ILE H 214    CG1  CG2  CD1                                       
REMARK 470     VAL H 215    CG1  CG2                                            
REMARK 470     PRO H 216    CG   CD                                             
REMARK 470     ARG H 217    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU L   2    CG   CD1  CD2                                       
REMARK 470     VAL L   3    CG1  CG2                                            
REMARK 470     MET L   4    CG   SD   CE                                        
REMARK 470     THR L   5    OG1  CG2                                            
REMARK 470     GLN L   6    CG   CD   OE1  NE2                                  
REMARK 470     THR L   7    OG1  CG2                                            
REMARK 470     PRO L   8    CG   CD                                             
REMARK 470     THR L  10    OG1  CG2                                            
REMARK 470     LEU L  11    CG   CD1  CD2                                       
REMARK 470     SER L  12    OG                                                  
REMARK 470     VAL L  13    CG1  CG2                                            
REMARK 470     THR L  14    OG1  CG2                                            
REMARK 470     PRO L  15    CG   CD                                             
REMARK 470     ASP L  17    CG   OD1  OD2                                       
REMARK 470     SER L  18    OG                                                  
REMARK 470     VAL L  19    CG1  CG2                                            
REMARK 470     SER L  20    OG                                                  
REMARK 470     LEU L  21    CG   CD1  CD2                                       
REMARK 470     SER L  22    OG                                                  
REMARK 470     CYS L  23    SG                                                  
REMARK 470     ARG L  24    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     SER L  26    OG                                                  
REMARK 470     GLN L  27    CG   CD   OE1  NE2                                  
REMARK 470     SER L  28    OG                                                  
REMARK 470     ILE L  29    CG1  CG2  CD1                                       
REMARK 470     SER L  30    OG                                                  
REMARK 470     ASN L  31    CG   OD1  ND2                                       
REMARK 470     HIS L  32    CG   ND1  CD2  CE1  NE2                             
REMARK 470     LEU L  33    CG   CD1  CD2                                       
REMARK 470     HIS L  34    CG   ND1  CD2  CE1  NE2                             
REMARK 470     TRP L  35    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP L  35    CZ3  CH2                                            
REMARK 470     TYR L  36    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     GLN L  37    CG   CD   OE1  NE2                                  
REMARK 470     GLN L  38    CG   CD   OE1  NE2                                  
REMARK 470     LYS L  39    CG   CD   CE   NZ                                   
REMARK 470     SER L  40    OG                                                  
REMARK 470     HIS L  41    CG   ND1  CD2  CE1  NE2                             
REMARK 470     GLU L  42    CG   CD   OE1  OE2                                  
REMARK 470     SER L  43    OG                                                  
REMARK 470     PRO L  44    CG   CD                                             
REMARK 470     ARG L  45    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU L  46    CG   CD1  CD2                                       
REMARK 470     LEU L  47    CG   CD1  CD2                                       
REMARK 470     ILE L  48    CG1  CG2  CD1                                       
REMARK 470     LYS L  49    CG   CD   CE   NZ                                   
REMARK 470     TYR L  50    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     SER L  52    OG                                                  
REMARK 470     GLN L  53    CG   CD   OE1  NE2                                  
REMARK 470     SER L  54    OG                                                  
REMARK 470     ILE L  55    CG1  CG2  CD1                                       
REMARK 470     SER L  56    OG                                                  
REMARK 470     ILE L  58    CG1  CG2  CD1                                       
REMARK 470     PRO L  59    CG   CD                                             
REMARK 470     SER L  60    OG                                                  
REMARK 470     ARG L  61    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     PHE L  62    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     SER L  63    OG                                                  
REMARK 470     SER L  65    OG                                                  
REMARK 470     SER L  67    OG                                                  
REMARK 470     THR L  69    OG1  CG2                                            
REMARK 470     ASP L  70    CG   OD1  OD2                                       
REMARK 470     PHE L  71    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     THR L  72    OG1  CG2                                            
REMARK 470     LEU L  73    CG   CD1  CD2                                       
REMARK 470     SER L  74    OG                                                  
REMARK 470     ILE L  75    CG1  CG2  CD1                                       
REMARK 470     ASN L  76    CG   OD1  ND2                                       
REMARK 470     SER L  77    OG                                                  
REMARK 470     VAL L  78    CG1  CG2                                            
REMARK 470     GLU L  79    CG   CD   OE1  OE2                                  
REMARK 470     THR L  80    OG1  CG2                                            
REMARK 470     GLU L  81    CG   CD   OE1  OE2                                  
REMARK 470     ASP L  82    CG   OD1  OD2                                       
REMARK 470     PHE L  83    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     MET L  85    CG   SD   CE                                        
REMARK 470     TYR L  86    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     PHE L  87    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     CYS L  88    SG                                                  
REMARK 470     GLN L  89    CG   CD   OE1  NE2                                  
REMARK 470     GLN L  90    CG   CD   OE1  NE2                                  
REMARK 470     SER L  91    OG                                                  
REMARK 470     ASN L  92    CG   OD1  ND2                                       
REMARK 470     SER L  93    OG                                                  
REMARK 470     TRP L  94    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP L  94    CZ3  CH2                                            
REMARK 470     PRO L  95    CG   CD                                             
REMARK 470     HIS L  96    CG   ND1  CD2  CE1  NE2                             
REMARK 470     THR L  97    OG1  CG2                                            
REMARK 470     PHE L  98    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     THR L 102    OG1  CG2                                            
REMARK 470     LYS L 103    CG   CD   CE   NZ                                   
REMARK 470     LEU L 104    CG   CD1  CD2                                       
REMARK 470     GLU L 105    CG   CD   OE1  OE2                                  
REMARK 470     ILE L 106    CG1  CG2  CD1                                       
REMARK 470     LYS L 107    CG   CD   CE   NZ                                   
REMARK 470     ARG L 108    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASP L 110    CG   OD1  OD2                                       
REMARK 470     PRO L 113    CG   CD                                             
REMARK 470     THR L 114    OG1  CG2                                            
REMARK 470     VAL L 115    CG1  CG2                                            
REMARK 470     SER L 116    OG                                                  
REMARK 470     ILE L 117    CG1  CG2  CD1                                       
REMARK 470     PHE L 118    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     PRO L 119    CG   CD                                             
REMARK 470     PRO L 120    CG   CD                                             
REMARK 470     SER L 121    OG                                                  
REMARK 470     SER L 122    OG                                                  
REMARK 470     GLU L 123    CG   CD   OE1  OE2                                  
REMARK 470     GLN L 124    CG   CD   OE1  NE2                                  
REMARK 470     LEU L 125    CG   CD1  CD2                                       
REMARK 470     THR L 126    OG1  CG2                                            
REMARK 470     SER L 127    OG                                                  
REMARK 470     SER L 131    OG                                                  
REMARK 470     VAL L 132    CG1  CG2                                            
REMARK 470     VAL L 133    CG1  CG2                                            
REMARK 470     CYS L 134    SG                                                  
REMARK 470     PHE L 135    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     LEU L 136    CG   CD1  CD2                                       
REMARK 470     ASN L 137    CG   OD1  ND2                                       
REMARK 470     ASN L 138    CG   OD1  ND2                                       
REMARK 470     PHE L 139    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     TYR L 140    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     PRO L 141    CG   CD                                             
REMARK 470     LYS L 142    CG   CD   CE   NZ                                   
REMARK 470     ASP L 143    CG   OD1  OD2                                       
REMARK 470     ILE L 144    CG1  CG2  CD1                                       
REMARK 470     ASN L 145    CG   OD1  ND2                                       
REMARK 470     VAL L 146    CG1  CG2                                            
REMARK 470     LYS L 147    CG   CD   CE   NZ                                   
REMARK 470     TRP L 148    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP L 148    CZ3  CH2                                            
REMARK 470     LYS L 149    CG   CD   CE   NZ                                   
REMARK 470     ILE L 150    CG1  CG2  CD1                                       
REMARK 470     ASP L 151    CG   OD1  OD2                                       
REMARK 470     SER L 153    OG                                                  
REMARK 470     GLU L 154    CG   CD   OE1  OE2                                  
REMARK 470     ARG L 155    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLN L 156    CG   CD   OE1  NE2                                  
REMARK 470     ASN L 157    CG   OD1  ND2                                       
REMARK 470     VAL L 159    CG1  CG2                                            
REMARK 470     LEU L 160    CG   CD1  CD2                                       
REMARK 470     ASN L 161    CG   OD1  ND2                                       
REMARK 470     SER L 162    OG                                                  
REMARK 470     TRP L 163    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP L 163    CZ3  CH2                                            
REMARK 470     THR L 164    OG1  CG2                                            
REMARK 470     ASP L 165    CG   OD1  OD2                                       
REMARK 470     GLN L 166    CG   CD   OE1  NE2                                  
REMARK 470     ASP L 167    CG   OD1  OD2                                       
REMARK 470     SER L 168    OG                                                  
REMARK 470     LYS L 169    CG   CD   CE   NZ                                   
REMARK 470     ASP L 170    CG   OD1  OD2                                       
REMARK 470     SER L 171    OG                                                  
REMARK 470     THR L 172    OG1  CG2                                            
REMARK 470     TYR L 173    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     SER L 174    OG                                                  
REMARK 470     MET L 175    CG   SD   CE                                        
REMARK 470     SER L 176    OG                                                  
REMARK 470     SER L 177    OG                                                  
REMARK 470     THR L 178    OG1  CG2                                            
REMARK 470     LEU L 179    CG   CD1  CD2                                       
REMARK 470     THR L 180    OG1  CG2                                            
REMARK 470     LEU L 181    CG   CD1  CD2                                       
REMARK 470     THR L 182    OG1  CG2                                            
REMARK 470     LYS L 183    CG   CD   CE   NZ                                   
REMARK 470     ASP L 184    CG   OD1  OD2                                       
REMARK 470     GLU L 185    CG   CD   OE1  OE2                                  
REMARK 470     TYR L 186    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     GLU L 187    CG   CD   OE1  OE2                                  
REMARK 470     ARG L 188    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     HIS L 189    CG   ND1  CD2  CE1  NE2                             
REMARK 470     ASN L 190    CG   OD1  ND2                                       
REMARK 470     SER L 191    OG                                                  
REMARK 470     TYR L 192    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     THR L 193    OG1  CG2                                            
REMARK 470     CYS L 194    SG                                                  
REMARK 470     GLU L 195    CG   CD   OE1  OE2                                  
REMARK 470     THR L 197    OG1  CG2                                            
REMARK 470     HIS L 198    CG   ND1  CD2  CE1  NE2                             
REMARK 470     LYS L 199    CG   CD   CE   NZ                                   
REMARK 470     THR L 200    OG1  CG2                                            
REMARK 470     SER L 201    OG                                                  
REMARK 470     SER L 203    OG                                                  
REMARK 470     PRO L 204    CG   CD                                             
REMARK 470     ILE L 205    CG1  CG2  CD1                                       
REMARK 470     VAL L 206    CG1  CG2                                            
REMARK 470     LYS L 207    CG   CD   CE   NZ                                   
REMARK 470     SER L 208    OG                                                  
REMARK 470     PHE L 209    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASN L 210    CG   OD1  ND2                                       
REMARK 470     ARG L 211    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ASN L 212    CG   OD1  ND2                                       
REMARK 470     GLU L 213    CG   CD   OE1  OE2                                  
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES                                       
REMARK 500                                                                      
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES              
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE               
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                 
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)              
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999                        
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996                     
REMARK 500                                                                      
REMARK 500  M RES CSSEQI ATM1   ATM2   ATM3                                     
REMARK 500    PRO A  41   C   -  N   -  CA  ANGL. DEV. =  10.2 DEGREES          
REMARK 500    ALA A  81   N   -  CA  -  CB  ANGL. DEV. =   8.5 DEGREES          
REMARK 500    PRO A 363   C   -  N   -  CA  ANGL. DEV. =  10.1 DEGREES          
REMARK 500    ALA A 432   N   -  CA  -  CB  ANGL. DEV. =   8.6 DEGREES          
REMARK 500    SER A 894   N   -  CA  -  CB  ANGL. DEV. = -12.2 DEGREES          
REMARK 500    PRO B 176   C   -  N   -  CA  ANGL. DEV. =  11.5 DEGREES          
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: TORSION ANGLES                                             
REMARK 500                                                                      
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:            
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)                    
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-           
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400            
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        PSI       PHI                                   
REMARK 500    GLN A  47      109.06    -44.27                                   
REMARK 500    SER A  63     -138.48     47.46                                   
REMARK 500    ALA A  74      -16.55   -150.14                                   
REMARK 500    TYR A  80      -70.65   -145.48                                   
REMARK 500    GLN A 102     -121.78     47.87                                   
REMARK 500    ALA A 140       62.39   -152.24                                   
REMARK 500    ASP A 148     -159.02   -128.83                                   
REMARK 500    ALA A 166     -113.27     75.33                                   
REMARK 500    ASP A 167       22.75   -141.47                                   
REMARK 500    THR A 249       -3.66     75.40                                   
REMARK 500    TYR A 275       57.28     74.55                                   
REMARK 500    ARG A 339       75.18    -61.91                                   
REMARK 500    ASP A 368       79.68     72.31                                   
REMARK 500    LYS A 369       72.64    -65.51                                   
REMARK 500    SER A 399      -85.22   -145.47                                   
REMARK 500    ALA A 426       65.50   -150.86                                   
REMARK 500    ARG A 529      -28.98     65.41                                   
REMARK 500    LYS A 551      -31.05   -131.26                                   
REMARK 500    TYR A 565      -58.10   -123.93                                   
REMARK 500    ASP A 595     -118.76     64.51                                   
REMARK 500    GLN A 703       49.79     30.17                                   
REMARK 500    ALA A 740       52.58   -141.35                                   
REMARK 500    SER A 749      -72.42    -39.86                                   
REMARK 500    THR A 768      157.48     60.44                                   
REMARK 500    TYR A 801      -55.56   -132.67                                   
REMARK 500    ASN A 804     -115.01     55.79                                   
REMARK 500    LYS A 834       66.18   -101.90                                   
REMARK 500    SER A 836     -141.01     44.10                                   
REMARK 500    VAL A 876      -58.69   -120.48                                   
REMARK 500    ASN A 913       92.49   -166.53                                   
REMARK 500    GLN A 914     -121.47     49.26                                   
REMARK 500    PRO B   2       99.23    -66.96                                   
REMARK 500    ILE B   4      -70.72     56.99                                   
REMARK 500    SER B  35      -71.52    178.70                                   
REMARK 500    CYS B  38      -68.88     66.14                                   
REMARK 500    ASP B  39     -122.00     34.05                                   
REMARK 500    ASP B  76     -161.30    -76.80                                   
REMARK 500    SER B  77     -108.33     73.51                                   
REMARK 500    SER B  84      -76.08    -83.69                                   
REMARK 500    ASP B 158      158.36     83.59                                   
REMARK 500    SER B 162      -66.64    -21.82                                   
REMARK 500    ILE B 167        2.08    -40.27                                   
REMARK 500    ASN B 175       77.73   -150.50                                   
REMARK 500    PRO B 176     -179.95    -61.80                                   
REMARK 500    SER B 337       19.52     48.04                                   
REMARK 500    ASN B 376     -115.79     52.03                                   
REMARK 500    GLU B 409       57.07    -69.56                                   
REMARK 500    SER B 445      -90.50     59.92                                   
REMARK 500    HIS B 446     -177.50    -63.97                                   
REMARK 500    ARG B 447      -26.34     91.81                                   
REMARK 500                                                                      
REMARK 500 THIS ENTRY HAS      76 RAMACHANDRAN OUTLIERS.                        
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 900                                                                      
REMARK 900 RELATED ENTRIES                                                      
REMARK 900 RELATED ID: 5OPY   RELATED DB: PDB                                   
REMARK 900 LM609 CRYSTAL STRUCTURE                                              
REMARK 900 RELATED ID: 6AVQ   RELATED DB: PDB                                   
REMARK 900 PSEUDO-ATOMIC MODEL OF ?V?3 INTEGRIN BENT STATE BOUND TO LM609 FAB   
REMARK 900 RELATED ID: EMD-7011   RELATED DB: EMDB                              
REMARK 900 EM DENSITY MAP OF ?V?3 INTEGRIN BENT STATE BOUND TO LM609 FAB        
REMARK 900 RELATED ID: EMD-7012   RELATED DB: EMDB                              
REMARK 900 HUMAN ALPHA-V BETA-3 INTEGRIN (INTERMEDIATE CONFORMATION) IN         
REMARK 900 COMPLEX WITH THE THERAPEUTIC ANTIBODY LM609                          
REMARK 900 RELATED ID: EMD-7013   RELATED DB: EMDB                              
REMARK 900 HUMAN ALPHA-V BETA-3 INTEGRIN (OPEN CONFORMATION) IN COMPLEX WITH    
REMARK 900 THE THERAPEUTIC ANTIBODY LM609                                       
DBREF  6AVR A    1   957  UNP    P06756   ITAV_HUMAN      31    987             
DBREF  6AVR B    1   692  UNP    P05106   ITB3_HUMAN      27    718             
DBREF  6AVR H    1   257  PDB    6AVR     6AVR             1    257             
DBREF  6AVR L    1   214  PDB    6AVR     6AVR             1    214             
SEQADV 6AVR ILE A  753  UNP  P06756    VAL   783 CONFLICT                       
SEQRES   1 A  957  PHE ASN LEU ASP VAL ASP SER PRO ALA GLU TYR SER GLY          
SEQRES   2 A  957  PRO GLU GLY SER TYR PHE GLY PHE ALA VAL ASP PHE PHE          
SEQRES   3 A  957  VAL PRO SER ALA SER SER ARG MET PHE LEU LEU VAL GLY          
SEQRES   4 A  957  ALA PRO LYS ALA ASN THR THR GLN PRO GLY ILE VAL GLU          
SEQRES   5 A  957  GLY GLY GLN VAL LEU LYS CYS ASP TRP SER SER THR ARG          
SEQRES   6 A  957  ARG CYS GLN PRO ILE GLU PHE ASP ALA THR GLY ASN ARG          
SEQRES   7 A  957  ASP TYR ALA LYS ASP ASP PRO LEU GLU PHE LYS SER HIS          
SEQRES   8 A  957  GLN TRP PHE GLY ALA SER VAL ARG SER LYS GLN ASP LYS          
SEQRES   9 A  957  ILE LEU ALA CYS ALA PRO LEU TYR HIS TRP ARG THR GLU          
SEQRES  10 A  957  MET LYS GLN GLU ARG GLU PRO VAL GLY THR CYS PHE LEU          
SEQRES  11 A  957  GLN ASP GLY THR LYS THR VAL GLU TYR ALA PRO CYS ARG          
SEQRES  12 A  957  SER GLN ASP ILE ASP ALA ASP GLY GLN GLY PHE CYS GLN          
SEQRES  13 A  957  GLY GLY PHE SER ILE ASP PHE THR LYS ALA ASP ARG VAL          
SEQRES  14 A  957  LEU LEU GLY GLY PRO GLY SER PHE TYR TRP GLN GLY GLN          
SEQRES  15 A  957  LEU ILE SER ASP GLN VAL ALA GLU ILE VAL SER LYS TYR          
SEQRES  16 A  957  ASP PRO ASN VAL TYR SER ILE LYS TYR ASN ASN GLN LEU          
SEQRES  17 A  957  ALA THR ARG THR ALA GLN ALA ILE PHE ASP ASP SER TYR          
SEQRES  18 A  957  LEU GLY TYR SER VAL ALA VAL GLY ASP PHE ASN GLY ASP          
SEQRES  19 A  957  GLY ILE ASP ASP PHE VAL SER GLY VAL PRO ARG ALA ALA          
SEQRES  20 A  957  ARG THR LEU GLY MET VAL TYR ILE TYR ASP GLY LYS ASN          
SEQRES  21 A  957  MET SER SER LEU TYR ASN PHE THR GLY GLU GLN MET ALA          
SEQRES  22 A  957  ALA TYR PHE GLY PHE SER VAL ALA ALA THR ASP ILE ASN          
SEQRES  23 A  957  GLY ASP ASP TYR ALA ASP VAL PHE ILE GLY ALA PRO LEU          
SEQRES  24 A  957  PHE MET ASP ARG GLY SER ASP GLY LYS LEU GLN GLU VAL          
SEQRES  25 A  957  GLY GLN VAL SER VAL SER LEU GLN ARG ALA SER GLY ASP          
SEQRES  26 A  957  PHE GLN THR THR LYS LEU ASN GLY PHE GLU VAL PHE ALA          
SEQRES  27 A  957  ARG PHE GLY SER ALA ILE ALA PRO LEU GLY ASP LEU ASP          
SEQRES  28 A  957  GLN ASP GLY PHE ASN ASP ILE ALA ILE ALA ALA PRO TYR          
SEQRES  29 A  957  GLY GLY GLU ASP LYS LYS GLY ILE VAL TYR ILE PHE ASN          
SEQRES  30 A  957  GLY ARG SER THR GLY LEU ASN ALA VAL PRO SER GLN ILE          
SEQRES  31 A  957  LEU GLU GLY GLN TRP ALA ALA ARG SER MET PRO PRO SER          
SEQRES  32 A  957  PHE GLY TYR SER MET LYS GLY ALA THR ASP ILE ASP LYS          
SEQRES  33 A  957  ASN GLY TYR PRO ASP LEU ILE VAL GLY ALA PHE GLY VAL          
SEQRES  34 A  957  ASP ARG ALA ILE LEU TYR ARG ALA ARG PRO VAL ILE THR          
SEQRES  35 A  957  VAL ASN ALA GLY LEU GLU VAL TYR PRO SER ILE LEU ASN          
SEQRES  36 A  957  GLN ASP ASN LYS THR CYS SER LEU PRO GLY THR ALA LEU          
SEQRES  37 A  957  LYS VAL SER CYS PHE ASN VAL ARG PHE CYS LEU LYS ALA          
SEQRES  38 A  957  ASP GLY LYS GLY VAL LEU PRO ARG LYS LEU ASN PHE GLN          
SEQRES  39 A  957  VAL GLU LEU LEU LEU ASP LYS LEU LYS GLN LYS GLY ALA          
SEQRES  40 A  957  ILE ARG ARG ALA LEU PHE LEU TYR SER ARG SER PRO SER          
SEQRES  41 A  957  HIS SER LYS ASN MET THR ILE SER ARG GLY GLY LEU MET          
SEQRES  42 A  957  GLN CYS GLU GLU LEU ILE ALA TYR LEU ARG ASP GLU SER          
SEQRES  43 A  957  GLU PHE ARG ASP LYS LEU THR PRO ILE THR ILE PHE MET          
SEQRES  44 A  957  GLU TYR ARG LEU ASP TYR ARG THR ALA ALA ASP THR THR          
SEQRES  45 A  957  GLY LEU GLN PRO ILE LEU ASN GLN PHE THR PRO ALA ASN          
SEQRES  46 A  957  ILE SER ARG GLN ALA HIS ILE LEU LEU ASP CYS GLY GLU          
SEQRES  47 A  957  ASP ASN VAL CYS LYS PRO LYS LEU GLU VAL SER VAL ASP          
SEQRES  48 A  957  SER ASP GLN LYS LYS ILE TYR ILE GLY ASP ASP ASN PRO          
SEQRES  49 A  957  LEU THR LEU ILE VAL LYS ALA GLN ASN GLN GLY GLU GLY          
SEQRES  50 A  957  ALA TYR GLU ALA GLU LEU ILE VAL SER ILE PRO LEU GLN          
SEQRES  51 A  957  ALA ASP PHE ILE GLY VAL VAL ARG ASN ASN GLU ALA LEU          
SEQRES  52 A  957  ALA ARG LEU SER CYS ALA PHE LYS THR GLU ASN GLN THR          
SEQRES  53 A  957  ARG GLN VAL VAL CYS ASP LEU GLY ASN PRO MET LYS ALA          
SEQRES  54 A  957  GLY THR GLN LEU LEU ALA GLY LEU ARG PHE SER VAL HIS          
SEQRES  55 A  957  GLN GLN SER GLU MET ASP THR SER VAL LYS PHE ASP LEU          
SEQRES  56 A  957  GLN ILE GLN SER SER ASN LEU PHE ASP LYS VAL SER PRO          
SEQRES  57 A  957  VAL VAL SER HIS LYS VAL ASP LEU ALA VAL LEU ALA ALA          
SEQRES  58 A  957  VAL GLU ILE ARG GLY VAL SER SER PRO ASP HIS ILE PHE          
SEQRES  59 A  957  LEU PRO ILE PRO ASN TRP GLU HIS LYS GLU ASN PRO GLU          
SEQRES  60 A  957  THR GLU GLU ASP VAL GLY PRO VAL VAL GLN HIS ILE TYR          
SEQRES  61 A  957  GLU LEU ARG ASN ASN GLY PRO SER SER PHE SER LYS ALA          
SEQRES  62 A  957  MET LEU HIS LEU GLN TRP PRO TYR LYS TYR ASN ASN ASN          
SEQRES  63 A  957  THR LEU LEU TYR ILE LEU HIS TYR ASP ILE ASP GLY PRO          
SEQRES  64 A  957  MET ASN CYS THR SER ASP MET GLU ILE ASN PRO LEU ARG          
SEQRES  65 A  957  ILE LYS ILE SER SER LEU GLN THR THR GLU LYS ASN ASP          
SEQRES  66 A  957  THR VAL ALA GLY GLN GLY GLU ARG ASP HIS LEU ILE THR          
SEQRES  67 A  957  LYS ARG ASP LEU ALA LEU SER GLU GLY ASP ILE HIS THR          
SEQRES  68 A  957  LEU GLY CYS GLY VAL ALA GLN CYS LEU LYS ILE VAL CYS          
SEQRES  69 A  957  GLN VAL GLY ARG LEU ASP ARG GLY LYS SER ALA ILE LEU          
SEQRES  70 A  957  TYR VAL LYS SER LEU LEU TRP THR GLU THR PHE MET ASN          
SEQRES  71 A  957  LYS GLU ASN GLN ASN HIS SER TYR SER LEU LYS SER SER          
SEQRES  72 A  957  ALA SER PHE ASN VAL ILE GLU PHE PRO TYR LYS ASN LEU          
SEQRES  73 A  957  PRO ILE GLU ASP ILE THR ASN SER THR LEU VAL THR THR          
SEQRES  74 A  957  ASN VAL THR TRP GLY ILE GLN PRO                              
SEQRES   1 B  692  GLY PRO ASN ILE CYS THR THR ARG GLY VAL SER SER CYS          
SEQRES   2 B  692  GLN GLN CYS LEU ALA VAL SER PRO MET CYS ALA TRP CYS          
SEQRES   3 B  692  SER ASP GLU ALA LEU PRO LEU GLY SER PRO ARG CYS ASP          
SEQRES   4 B  692  LEU LYS GLU ASN LEU LEU LYS ASP ASN CYS ALA PRO GLU          
SEQRES   5 B  692  SER ILE GLU PHE PRO VAL SER GLU ALA ARG VAL LEU GLU          
SEQRES   6 B  692  ASP ARG PRO LEU SER ASP LYS GLY SER GLY ASP SER SER          
SEQRES   7 B  692  GLN VAL THR GLN VAL SER PRO GLN ARG ILE ALA LEU ARG          
SEQRES   8 B  692  LEU ARG PRO ASP ASP SER LYS ASN PHE SER ILE GLN VAL          
SEQRES   9 B  692  ARG GLN VAL GLU ASP TYR PRO VAL ASP ILE TYR TYR LEU          
SEQRES  10 B  692  MET ASP LEU SER TYR SER MET LYS ASP ASP LEU TRP SER          
SEQRES  11 B  692  ILE GLN ASN LEU GLY THR LYS LEU ALA THR GLN MET ARG          
SEQRES  12 B  692  LYS LEU THR SER ASN LEU ARG ILE GLY PHE GLY ALA PHE          
SEQRES  13 B  692  VAL ASP LYS PRO VAL SER PRO TYR MET TYR ILE SER PRO          
SEQRES  14 B  692  PRO GLU ALA LEU GLU ASN PRO CYS TYR ASP MET LYS THR          
SEQRES  15 B  692  THR CYS LEU PRO MET PHE GLY TYR LYS HIS VAL LEU THR          
SEQRES  16 B  692  LEU THR ASP GLN VAL THR ARG PHE ASN GLU GLU VAL LYS          
SEQRES  17 B  692  LYS GLN SER VAL SER ARG ASN ARG ASP ALA PRO GLU GLY          
SEQRES  18 B  692  GLY PHE ASP ALA ILE MET GLN ALA THR VAL CYS ASP GLU          
SEQRES  19 B  692  LYS ILE GLY TRP ARG ASN ASP ALA SER HIS LEU LEU VAL          
SEQRES  20 B  692  PHE THR THR ASP ALA LYS THR HIS ILE ALA LEU ASP GLY          
SEQRES  21 B  692  ARG LEU ALA GLY ILE VAL GLN PRO ASN ASP GLY GLN CYS          
SEQRES  22 B  692  HIS VAL GLY SER ASP ASN HIS TYR SER ALA SER THR THR          
SEQRES  23 B  692  MET ASP TYR PRO SER LEU GLY LEU MET THR GLU LYS LEU          
SEQRES  24 B  692  SER GLN LYS ASN ILE ASN LEU ILE PHE ALA VAL THR GLU          
SEQRES  25 B  692  ASN VAL VAL ASN LEU TYR GLN ASN TYR SER GLU LEU ILE          
SEQRES  26 B  692  PRO GLY THR THR VAL GLY VAL LEU SER MET ASP SER SER          
SEQRES  27 B  692  ASN VAL LEU GLN LEU ILE VAL ASP ALA TYR GLY LYS ILE          
SEQRES  28 B  692  ARG SER LYS VAL GLU LEU GLU VAL ARG ASP LEU PRO GLU          
SEQRES  29 B  692  GLU LEU SER LEU SER PHE ASN ALA THR CYS LEU ASN ASN          
SEQRES  30 B  692  GLU VAL ILE PRO GLY LEU LYS SER CYS MET GLY LEU LYS          
SEQRES  31 B  692  ILE GLY ASP THR VAL SER PHE SER ILE GLU ALA LYS VAL          
SEQRES  32 B  692  ARG GLY CYS PRO GLN GLU LYS GLU LYS SER PHE THR ILE          
SEQRES  33 B  692  LYS PRO VAL GLY PHE LYS ASP SER LEU ILE VAL GLN VAL          
SEQRES  34 B  692  THR PHE ASP CYS ASP CYS ALA CYS GLN ALA GLN ALA GLU          
SEQRES  35 B  692  PRO ASN SER HIS ARG CYS ASN ASN GLY ASN GLY THR PHE          
SEQRES  36 B  692  GLU CYS GLY VAL CYS ARG CYS GLY PRO GLY TRP LEU GLY          
SEQRES  37 B  692  SER GLN CYS GLU CYS SER GLU GLU ASP TYR ARG PRO SER          
SEQRES  38 B  692  GLN GLN ASP GLU CYS SER PRO ARG GLU GLY GLN PRO VAL          
SEQRES  39 B  692  CYS SER GLN ARG GLY GLU CYS LEU CYS GLY GLN CYS VAL          
SEQRES  40 B  692  CYS HIS SER SER ASP PHE GLY LYS ILE THR GLY LYS TYR          
SEQRES  41 B  692  CYS GLU CYS ASP ASP PHE SER CYS VAL ARG TYR LYS GLY          
SEQRES  42 B  692  GLU MET CYS SER GLY HIS GLY GLN CYS SER CYS GLY ASP          
SEQRES  43 B  692  CYS LEU CYS ASP SER ASP TRP THR GLY TYR TYR CYS ASN          
SEQRES  44 B  692  CYS THR THR ARG THR ASP THR CYS MET SER SER ASN GLY          
SEQRES  45 B  692  LEU LEU CYS SER GLY ARG GLY LYS CYS GLU CYS GLY SER          
SEQRES  46 B  692  CYS VAL CYS ILE GLN PRO GLY SER TYR GLY ASP THR CYS          
SEQRES  47 B  692  GLU LYS CYS PRO THR CYS PRO ASP ALA CYS THR PHE LYS          
SEQRES  48 B  692  LYS GLU CYS VAL GLU CYS LYS LYS PHE ASP ARG GLY ALA          
SEQRES  49 B  692  LEU HIS ASP GLU ASN THR CYS ASN ARG TYR CYS ARG ASP          
SEQRES  50 B  692  GLU ILE GLU SER VAL LYS GLU LEU LYS ASP THR GLY LYS          
SEQRES  51 B  692  ASP ALA VAL ASN CYS THR TYR LYS ASN GLU ASP ASP CYS          
SEQRES  52 B  692  VAL VAL ARG PHE GLN TYR TYR GLU ASP SER SER GLY LYS          
SEQRES  53 B  692  SER ILE LEU TYR VAL VAL GLU GLU PRO GLU CYS PRO LYS          
SEQRES  54 B  692  GLY PRO ASP                                                  
SEQRES   1 H  257  GLU VAL GLN LEU GLU GLU SER GLY GLY GLY LEU VAL LYS          
SEQRES   2 H  257  PRO GLY GLY SER LEU LYS LEU SER CYS ALA ALA SER GLY          
SEQRES   3 H  257  PHE ALA PHE SER SER TYR ASP MET SER TRP VAL ARG GLN          
SEQRES   4 H  257  ILE PRO GLU LYS ARG LEU GLU TRP VAL ALA LYS VAL SER          
SEQRES   5 H  257  SER GLY GLY GLY SER THR TYR TYR LEU ASP THR VAL GLN          
SEQRES   6 H  257  GLY ARG PHE THR ILE SER ARG ASP ASN ALA LYS ASN THR          
SEQRES   7 H  257  LEU TYR LEU GLN MET SER SER LEU ASN SER GLU ASP THR          
SEQRES   8 H  257  ALA MET TYR TYR CYS ALA ARG HIS ASN TYR GLY SER PHE          
SEQRES   9 H  257  ALA TYR TRP GLY GLN GLY THR LEU VAL THR VAL SER ALA          
SEQRES  10 H  257  ALA LYS THR THR PRO PRO SER VAL TYR PRO LEU ALA PRO          
SEQRES  11 H  257  GLY SER ALA ALA GLN THR ASN SER MET VAL THR LEU GLY          
SEQRES  12 H  257  CYS LEU VAL LYS GLY TYR PHE PRO GLU PRO VAL THR VAL          
SEQRES  13 H  257  THR TRP ASN SER GLY SER LEU SER SER GLY VAL HIS THR          
SEQRES  14 H  257  PHE PRO ALA VAL LEU GLN SER ASP LEU TYR THR LEU SER          
SEQRES  15 H  257  SER SER VAL THR VAL PRO SER SER THR TRP PRO SER GLU          
SEQRES  16 H  257  THR VAL THR CYS ASN VAL ALA HIS PRO ALA SER SER THR          
SEQRES  17 H  257  LYS VAL ASP LYS LYS ILE VAL PRO ARG ASP CYS GLY ALA          
SEQRES  18 H  257  SER ASP ASP ASP ASP LYS ALA GLY TRP SER HIS PRO GLN          
SEQRES  19 H  257  PHE GLU LYS GLY GLY GLY SER GLY GLY GLY SER GLY GLY          
SEQRES  20 H  257  GLY SER TRP SER HIS PRO GLN PHE GLU LYS                      
SEQRES   1 L  214  GLU LEU VAL MET THR GLN THR PRO ALA THR LEU SER VAL          
SEQRES   2 L  214  THR PRO GLY ASP SER VAL SER LEU SER CYS ARG ALA SER          
SEQRES   3 L  214  GLN SER ILE SER ASN HIS LEU HIS TRP TYR GLN GLN LYS          
SEQRES   4 L  214  SER HIS GLU SER PRO ARG LEU LEU ILE LYS TYR ALA SER          
SEQRES   5 L  214  GLN SER ILE SER GLY ILE PRO SER ARG PHE SER GLY SER          
SEQRES   6 L  214  GLY SER GLY THR ASP PHE THR LEU SER ILE ASN SER VAL          
SEQRES   7 L  214  GLU THR GLU ASP PHE GLY MET TYR PHE CYS GLN GLN SER          
SEQRES   8 L  214  ASN SER TRP PRO HIS THR PHE GLY GLY GLY THR LYS LEU          
SEQRES   9 L  214  GLU ILE LYS ARG ALA ASP ALA ALA PRO THR VAL SER ILE          
SEQRES  10 L  214  PHE PRO PRO SER SER GLU GLN LEU THR SER GLY GLY ALA          
SEQRES  11 L  214  SER VAL VAL CYS PHE LEU ASN ASN PHE TYR PRO LYS ASP          
SEQRES  12 L  214  ILE ASN VAL LYS TRP LYS ILE ASP GLY SER GLU ARG GLN          
SEQRES  13 L  214  ASN GLY VAL LEU ASN SER TRP THR ASP GLN ASP SER LYS          
SEQRES  14 L  214  ASP SER THR TYR SER MET SER SER THR LEU THR LEU THR          
SEQRES  15 L  214  LYS ASP GLU TYR GLU ARG HIS ASN SER TYR THR CYS GLU          
SEQRES  16 L  214  ALA THR HIS LYS THR SER THR SER PRO ILE VAL LYS SER          
SEQRES  17 L  214  PHE ASN ARG ASN GLU CYS                                      
HELIX    1 AA1 GLY A  175  GLN A  180  1                                   6    
HELIX    2 AA2 VAL A  188  LYS A  194  1                                   7    
HELIX    3 AA3 GLN A  214  ASP A  218  5                                   5    
HELIX    4 AA4 PHE A  427  VAL A  429  5                                   3    
HELIX    5 AA5 TYR A  565  ALA A  569  5                                   5    
HELIX    6 AA6 THR A  768  VAL A  772  5                                   5    
HELIX    7 AA7 THR A  905  PHE A  908  5                                   4    
HELIX    8 AA8 ILE B    4  GLY B    9  1                                   6    
HELIX    9 AA9 SER B   12  SER B   20  1                                   9    
HELIX   10 AB1 LEU B   40  ASP B   47  1                                   8    
HELIX   11 AB2 SER B  121  SER B  123  5                                   3    
HELIX   12 AB3 MET B  124  ILE B  131  1                                   8    
HELIX   13 AB4 GLN B  132  LEU B  134  5                                   3    
HELIX   14 AB5 GLY B  135  ARG B  143  1                                   9    
HELIX   15 AB6 PRO B  170  GLU B  174  5                                   5    
HELIX   16 AB7 CYS B  177  LYS B  181  5                                   5    
HELIX   17 AB8 VAL B  200  LYS B  209  1                                  10    
HELIX   18 AB9 GLY B  221  CYS B  232  1                                  12    
HELIX   19 AC1 CYS B  232  GLY B  237  1                                   6    
HELIX   20 AC2 LEU B  258  GLY B  264  5                                   7    
HELIX   21 AC3 TYR B  281  THR B  286  5                                   6    
HELIX   22 AC4 SER B  291  LYS B  302  1                                  12    
HELIX   23 AC5 VAL B  314  LEU B  324  1                                  11    
HELIX   24 AC6 ASN B  339  ARG B  352  1                                  14    
HELIX   25 AC7 CYS B  435  GLN B  440  1                                   6    
HELIX   26 AC8 SER B  487  GLY B  491  5                                   5    
HELIX   27 AC9 GLU B  534  GLY B  538  5                                   5    
HELIX   28 AD1 LEU B  573  ARG B  578  5                                   6    
HELIX   29 AD2 ALA B  607  LYS B  619  1                                  13    
HELIX   30 AD3 GLY B  623  GLU B  628  1                                   6    
HELIX   31 AD4 THR B  630  CYS B  635  1                                   6    
HELIX   32 AD5 ALA H   28  TYR H   32  5                                   5    
HELIX   33 AD6 ASN H   87  THR H   91  5                                   5    
HELIX   34 AD7 SER H  160  SER H  162  5                                   3    
HELIX   35 AD8 SER H  190  TRP H  192  5                                   3    
HELIX   36 AD9 PRO H  204  SER H  207  5                                   4    
HELIX   37 AE1 GLU L   79  PHE L   83  5                                   5    
HELIX   38 AE2 SER L  121  SER L  127  1                                   7    
HELIX   39 AE3 LYS L  183  GLU L  187  1                                   5    
SHEET    1 AA1 4 ALA A   9  SER A  12  0                                        
SHEET    2 AA1 4 ARG A 431  TYR A 435 -1  O  LEU A 434   N  ALA A   9           
SHEET    3 AA1 4 LEU A 422  ALA A 426 -1  N  VAL A 424   O  ILE A 433           
SHEET    4 AA1 4 MET A 408  GLY A 410 -1  N  LYS A 409   O  ILE A 423           
SHEET    1 AA2 4 VAL A  23  PHE A  26  0                                        
SHEET    2 AA2 4 PHE A  35  ALA A  40 -1  O  PHE A  35   N  PHE A  26           
SHEET    3 AA2 4 GLN A  55  ASP A  60 -1  O  CYS A  59   N  LEU A  36           
SHEET    4 AA2 4 CYS A  67  PRO A  69 -1  O  GLN A  68   N  LYS A  58           
SHEET    1 AA3 3 GLU A  87  PHE A  88  0                                        
SHEET    2 AA3 3 HIS A 113  THR A 116 -1  O  HIS A 113   N  PHE A  88           
SHEET    3 AA3 3 LYS A 119  PRO A 124 -1  O  GLU A 123   N  TRP A 114           
SHEET    1 AA4 4 VAL A  98  LYS A 101  0                                        
SHEET    2 AA4 4 LYS A 104  ALA A 109 -1  O  LEU A 106   N  ARG A  99           
SHEET    3 AA4 4 THR A 127  ASP A 132 -1  O  GLN A 131   N  ILE A 105           
SHEET    4 AA4 4 LYS A 135  TYR A 139 -1  O  LYS A 135   N  ASP A 132           
SHEET    1 AA5 4 ILE A 161  PHE A 163  0                                        
SHEET    2 AA5 4 ARG A 168  GLY A 172 -1  O  LEU A 170   N  ASP A 162           
SHEET    3 AA5 4 LEU A 183  GLN A 187 -1  O  ASP A 186   N  VAL A 169           
SHEET    4 AA5 4 LEU A 208  ALA A 209 -1  O  LEU A 208   N  SER A 185           
SHEET    1 AA6 4 VAL A 226  GLY A 229  0                                        
SHEET    2 AA6 4 ASP A 238  VAL A 243 -1  O  VAL A 240   N  ALA A 227           
SHEET    3 AA6 4 MET A 252  ASP A 257 -1  O  TYR A 254   N  SER A 241           
SHEET    4 AA6 4 ASN A 260  THR A 268 -1  O  LEU A 264   N  ILE A 255           
SHEET    1 AA7 4 SER A 279  THR A 283  0                                        
SHEET    2 AA7 4 ASP A 292  ALA A 297 -1  O  GLY A 296   N  SER A 279           
SHEET    3 AA7 4 GLN A 314  LEU A 319 -1  O  GLN A 314   N  ALA A 297           
SHEET    4 AA7 4 GLN A 327  ASN A 332 -1  O  GLN A 327   N  LEU A 319           
SHEET    1 AA8 2 MET A 301  ARG A 303  0                                        
SHEET    2 AA8 2 LEU A 309  GLU A 311 -1  O  GLN A 310   N  ASP A 302           
SHEET    1 AA9 4 ALA A 343  GLY A 348  0                                        
SHEET    2 AA9 4 ASP A 357  ALA A 362 -1  O  ASP A 357   N  LEU A 347           
SHEET    3 AA9 4 ILE A 372  ILE A 375 -1  O  TYR A 374   N  ILE A 360           
SHEET    4 AA9 4 GLN A 389  GLU A 392 -1  O  LEU A 391   N  VAL A 373           
SHEET    1 AB1 2 GLY A 378  ARG A 379  0                                        
SHEET    2 AB1 2 GLY A 382  LEU A 383 -1  O  GLY A 382   N  ARG A 379           
SHEET    1 AB2 4 LYS A 459  SER A 462  0                                        
SHEET    2 AB2 4 LYS A 469  GLY A 483 -1  O  VAL A 470   N  CYS A 461           
SHEET    3 AB2 4 GLN A 534  LEU A 542 -1  O  LEU A 538   N  VAL A 475           
SHEET    4 AB2 4 ALA A 511  PHE A 513 -1  N  LEU A 512   O  TYR A 541           
SHEET    1 AB3 4 LYS A 459  SER A 462  0                                        
SHEET    2 AB3 4 LYS A 469  GLY A 483 -1  O  VAL A 470   N  CYS A 461           
SHEET    3 AB3 4 VAL A 440  VAL A 449 -1  N  GLU A 448   O  ARG A 476           
SHEET    4 AB3 4 ILE A 577  LEU A 578  1  O  ILE A 577   N  ILE A 441           
SHEET    1 AB4 5 ILE A 453  LEU A 454  0                                        
SHEET    2 AB4 5 ASN A 585  ILE A 592  1  O  HIS A 591   N  LEU A 454           
SHEET    3 AB4 5 ILE A 555  LEU A 563 -1  N  MET A 559   O  ILE A 586           
SHEET    4 AB4 5 LYS A 490  LEU A 499 -1  N  LEU A 498   O  PHE A 558           
SHEET    5 AB4 5 SER A 520  SER A 528 -1  O  HIS A 521   N  LEU A 497           
SHEET    1 AB5 4 LEU A 606  SER A 612  0                                        
SHEET    2 AB5 4 ASN A 623  ASN A 633 -1  O  GLN A 632   N  GLU A 607           
SHEET    3 AB5 4 LEU A 693  VAL A 701 -1  O  LEU A 693   N  ALA A 631           
SHEET    4 AB5 4 ALA A 651  VAL A 656 -1  N  ILE A 654   O  ARG A 698           
SHEET    1 AB6 6 LYS A 616  TYR A 618  0                                        
SHEET    2 AB6 6 VAL A 730  ALA A 737  1  O  ALA A 737   N  ILE A 617           
SHEET    3 AB6 6 SER A 710  GLN A 718 -1  N  PHE A 713   O  HIS A 732           
SHEET    4 AB6 6 GLU A 642  SER A 646 -1  N  ILE A 644   O  GLN A 716           
SHEET    5 AB6 6 GLN A 678  ASP A 682 -1  O  VAL A 679   N  VAL A 645           
SHEET    6 AB6 6 CYS A 668  LYS A 671 -1  N  LYS A 671   O  GLN A 678           
SHEET    1 AB7 4 VAL A 742  SER A 748  0                                        
SHEET    2 AB7 4 VAL A 775  ASN A 784 -1  O  GLU A 781   N  ARG A 745           
SHEET    3 AB7 4 SER A 894  LEU A 903 -1  O  VAL A 899   N  HIS A 778           
SHEET    4 AB7 4 LEU A 809  ILE A 816 -1  N  TYR A 810   O  LEU A 902           
SHEET    1 AB8 6 HIS A 752  PHE A 754  0                                        
SHEET    2 AB8 6 ILE A 941  THR A 952  1  O  THR A 952   N  ILE A 753           
SHEET    3 AB8 6 TYR A 918  GLU A 930 -1  N  TYR A 918   O  VAL A 951           
SHEET    4 AB8 6 LYS A 792  TYR A 803 -1  N  HIS A 796   O  SER A 925           
SHEET    5 AB8 6 GLN A 878  VAL A 886 -1  O  ILE A 882   N  LEU A 797           
SHEET    6 AB8 6 MET A 820  SER A 824 -1  N  ASN A 821   O  GLN A 885           
SHEET    1 AB9 4 ASN A 806  THR A 807  0                                        
SHEET    2 AB9 4 LYS A 792  TYR A 803 -1  N  TYR A 803   O  ASN A 806           
SHEET    3 AB9 4 TYR A 918  GLU A 930 -1  O  SER A 925   N  HIS A 796           
SHEET    4 AB9 4 THR A 871  LEU A 872  1  N  LEU A 872   O  SER A 919           
SHEET    1 AC1 6 GLU B  60  GLU B  65  0                                        
SHEET    2 AC1 6 ARG B  87  LEU B  92 -1  O  ALA B  89   N  ARG B  62           
SHEET    3 AC1 6 LEU B 425  PHE B 431  1  O  GLN B 428   N  ILE B  88           
SHEET    4 AC1 6 LYS B 412  PRO B 418 -1  N  LYS B 412   O  VAL B 429           
SHEET    5 AC1 6 VAL B 355  ARG B 360 -1  N  GLU B 358   O  LYS B 417           
SHEET    6 AC1 6 SER B 385  CYS B 386 -1  O  CYS B 386   N  VAL B 355           
SHEET    1 AC2 4 ASP B  96  ARG B 105  0                                        
SHEET    2 AC2 4 THR B 394  VAL B 403 -1  O  ALA B 401   N  LYS B  98           
SHEET    3 AC2 4 LEU B 366  LEU B 375 -1  N  ASN B 371   O  SER B 398           
SHEET    4 AC2 4 GLU B 378  PRO B 381 -1  O  ILE B 380   N  ALA B 372           
SHEET    1 AC3 6 GLY B 189  THR B 197  0                                        
SHEET    2 AC3 6 LEU B 149  ASP B 158 -1  N  ALA B 155   O  LYS B 191           
SHEET    3 AC3 6 VAL B 112  ASP B 119  1  N  MET B 118   O  GLY B 154           
SHEET    4 AC3 6 SER B 243  THR B 250  1  O  SER B 243   N  ASP B 113           
SHEET    5 AC3 6 ILE B 304  THR B 311  1  O  ILE B 307   N  PHE B 248           
SHEET    6 AC3 6 THR B 329  LEU B 333  1  O  THR B 329   N  PHE B 308           
SHEET    1 AC4 2 THR B 454  GLU B 456  0                                        
SHEET    2 AC4 2 VAL B 459  ARG B 461 -1  O  ARG B 461   N  THR B 454           
SHEET    1 AC5 2 GLU B 500  LEU B 502  0                                        
SHEET    2 AC5 2 GLN B 505  VAL B 507 -1  O  GLN B 505   N  LEU B 502           
SHEET    1 AC6 2 ILE B 516  THR B 517  0                                        
SHEET    2 AC6 2 CYS B 523  ASP B 524 -1  O  CYS B 523   N  THR B 517           
SHEET    1 AC7 2 GLY B 540  SER B 543  0                                        
SHEET    2 AC7 2 ASP B 546  CYS B 549 -1  O  LEU B 548   N  GLN B 541           
SHEET    1 AC8 2 TRP B 553  THR B 554  0                                        
SHEET    2 AC8 2 CYS B 560  THR B 561 -1  O  CYS B 560   N  THR B 554           
SHEET    1 AC9 2 LYS B 580  GLU B 582  0                                        
SHEET    2 AC9 2 SER B 585  VAL B 587 -1  O  VAL B 587   N  LYS B 580           
SHEET    1 AD1 4 GLU B 638  VAL B 642  0                                        
SHEET    2 AD1 4 LYS B 676  VAL B 682  1  O  LEU B 679   N  GLU B 638           
SHEET    3 AD1 4 VAL B 664  SER B 673 -1  N  TYR B 670   O  ILE B 678           
SHEET    4 AD1 4 ALA B 652  LYS B 658 -1  N  VAL B 653   O  TYR B 669           
SHEET    1 AD2 4 GLN H   3  SER H   7  0                                        
SHEET    2 AD2 4 LEU H  18  SER H  25 -1  O  SER H  25   N  GLN H   3           
SHEET    3 AD2 4 THR H  78  MET H  83 -1  O  LEU H  81   N  LEU H  20           
SHEET    4 AD2 4 THR H  69  ASP H  73 -1  N  SER H  71   O  TYR H  80           
SHEET    1 AD3 6 LEU H  11  VAL H  12  0                                        
SHEET    2 AD3 6 THR H 111  VAL H 115  1  O  THR H 114   N  VAL H  12           
SHEET    3 AD3 6 ALA H  92  ASN H 100 -1  N  TYR H  94   O  THR H 111           
SHEET    4 AD3 6 MET H  34  GLN H  39 -1  N  VAL H  37   O  TYR H  95           
SHEET    5 AD3 6 LEU H  45  VAL H  51 -1  O  GLU H  46   N  ARG H  38           
SHEET    6 AD3 6 THR H  58  TYR H  60 -1  O  TYR H  59   N  LYS H  50           
SHEET    1 AD4 4 LEU H  11  VAL H  12  0                                        
SHEET    2 AD4 4 THR H 111  VAL H 115  1  O  THR H 114   N  VAL H  12           
SHEET    3 AD4 4 ALA H  92  ASN H 100 -1  N  TYR H  94   O  THR H 111           
SHEET    4 AD4 4 SER H 103  TRP H 107 -1  O  TYR H 106   N  ARG H  98           
SHEET    1 AD5 4 SER H 124  LEU H 128  0                                        
SHEET    2 AD5 4 MET H 139  TYR H 149 -1  O  LEU H 145   N  TYR H 126           
SHEET    3 AD5 4 LEU H 178  PRO H 188 -1  O  LEU H 181   N  VAL H 146           
SHEET    4 AD5 4 VAL H 167  THR H 169 -1  N  HIS H 168   O  SER H 184           
SHEET    1 AD6 4 SER H 124  LEU H 128  0                                        
SHEET    2 AD6 4 MET H 139  TYR H 149 -1  O  LEU H 145   N  TYR H 126           
SHEET    3 AD6 4 LEU H 178  PRO H 188 -1  O  LEU H 181   N  VAL H 146           
SHEET    4 AD6 4 VAL H 173  GLN H 175 -1  N  GLN H 175   O  LEU H 178           
SHEET    1 AD7 3 THR H 155  TRP H 158  0                                        
SHEET    2 AD7 3 THR H 198  HIS H 203 -1  O  ASN H 200   N  THR H 157           
SHEET    3 AD7 3 THR H 208  LYS H 213 -1  O  LYS H 212   N  CYS H 199           
SHEET    1 AD8 4 MET L   4  THR L   7  0                                        
SHEET    2 AD8 4 VAL L  19  ALA L  25 -1  O  SER L  22   N  THR L   7           
SHEET    3 AD8 4 ASP L  70  ILE L  75 -1  O  PHE L  71   N  CYS L  23           
SHEET    4 AD8 4 PHE L  62  SER L  67 -1  N  SER L  65   O  THR L  72           
SHEET    1 AD9 6 THR L  10  VAL L  13  0                                        
SHEET    2 AD9 6 THR L 102  ILE L 106  1  O  GLU L 105   N  LEU L  11           
SHEET    3 AD9 6 GLY L  84  GLN L  90 -1  N  GLY L  84   O  LEU L 104           
SHEET    4 AD9 6 LEU L  33  GLN L  38 -1  N  GLN L  38   O  MET L  85           
SHEET    5 AD9 6 ARG L  45  LYS L  49 -1  O  LEU L  47   N  TRP L  35           
SHEET    6 AD9 6 GLN L  53  SER L  54 -1  O  GLN L  53   N  LYS L  49           
SHEET    1 AE1 4 THR L  10  VAL L  13  0                                        
SHEET    2 AE1 4 THR L 102  ILE L 106  1  O  GLU L 105   N  LEU L  11           
SHEET    3 AE1 4 GLY L  84  GLN L  90 -1  N  GLY L  84   O  LEU L 104           
SHEET    4 AE1 4 THR L  97  PHE L  98 -1  O  THR L  97   N  GLN L  90           
SHEET    1 AE2 4 THR L 114  PHE L 118  0                                        
SHEET    2 AE2 4 GLY L 129  PHE L 139 -1  O  VAL L 133   N  PHE L 118           
SHEET    3 AE2 4 TYR L 173  THR L 182 -1  O  LEU L 181   N  ALA L 130           
SHEET    4 AE2 4 VAL L 159  TRP L 163 -1  N  LEU L 160   O  THR L 178           
SHEET    1 AE3 4 SER L 153  ARG L 155  0                                        
SHEET    2 AE3 4 ASN L 145  ILE L 150 -1  N  ILE L 150   O  SER L 153           
SHEET    3 AE3 4 SER L 191  THR L 197 -1  O  GLU L 195   N  LYS L 147           
SHEET    4 AE3 4 ILE L 205  ASN L 210 -1  O  PHE L 209   N  TYR L 192           
CISPEP   1 PHE H  150    PRO H  151          0        -2.74                     
CISPEP   2 GLU H  152    PRO H  153          0        -3.23                     
CISPEP   3 TRP H  192    PRO H  193          0        12.79                     
CISPEP   4 THR L    7    PRO L    8          0        -7.23                     
CISPEP   5 TRP L   94    PRO L   95          0        -4.72                     
CISPEP   6 TYR L  140    PRO L  141          0        -4.03                     
CRYST1    1.000    1.000    1.000  90.00  90.00  90.00 P 1           1          
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      1.000000  0.000000  0.000000        0.00000                         
SCALE2      0.000000  1.000000  0.000000        0.00000                         
SCALE3      0.000000  0.000000  1.000000        0.00000                         
(ATOM LINES ARE NOT SHOWN.)
END                                                                             
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