HEADER VIRAL PROTEIN 02-MAR-18 6CM3
TITLE BG505 SOSIP IN COMPLEX WITH SCD4, 17B, 8ANC195
COMPND MOL_ID: 1;
COMPND 2 MOLECULE: ENVELOPE GLYCOPROTEIN GP160;
COMPND 3 CHAIN: A, B, C;
COMPND 4 SYNONYM: ENV POLYPROTEIN;
COMPND 5 ENGINEERED: YES;
COMPND 6 MOL_ID: 2;
COMPND 7 MOLECULE: ENVELOPE GLYCOPROTEIN GP160;
COMPND 8 CHAIN: D, E, F;
COMPND 9 SYNONYM: ENV POLYPROTEIN;
COMPND 10 ENGINEERED: YES;
COMPND 11 MOL_ID: 3;
COMPND 12 MOLECULE: T-CELL SURFACE GLYCOPROTEIN CD4;
COMPND 13 CHAIN: G, H, I;
COMPND 14 SYNONYM: T-CELL SURFACE ANTIGEN T4/LEU-3;
COMPND 15 ENGINEERED: YES;
COMPND 16 MOL_ID: 4;
COMPND 17 MOLECULE: 17B FAB LIGHT CHAIN;
COMPND 18 CHAIN: J, L, N;
COMPND 19 ENGINEERED: YES;
COMPND 20 MOL_ID: 5;
COMPND 21 MOLECULE: 17B FAB HEAVY CHAIN;
COMPND 22 CHAIN: K, M, O;
COMPND 23 ENGINEERED: YES;
COMPND 24 MOL_ID: 6;
COMPND 25 MOLECULE: 8ANC195 FAB HEAVY CHAIN;
COMPND 26 CHAIN: P, R, T;
COMPND 27 ENGINEERED: YES;
COMPND 28 MOL_ID: 7;
COMPND 29 MOLECULE: 8ANC195 FAB LIGHT CHAIN;
COMPND 30 CHAIN: Q, S, U;
COMPND 31 ENGINEERED: YES
SOURCE MOL_ID: 1;
SOURCE 2 ORGANISM_SCIENTIFIC: HUMAN IMMUNODEFICIENCY VIRUS 1;
SOURCE 3 ORGANISM_TAXID: 11676;
SOURCE 4 GENE: ENV;
SOURCE 5 EXPRESSION_SYSTEM: HOMO SAPIENS;
SOURCE 6 EXPRESSION_SYSTEM_COMMON: HUMAN;
SOURCE 7 EXPRESSION_SYSTEM_TAXID: 9606;
SOURCE 8 MOL_ID: 2;
SOURCE 9 ORGANISM_SCIENTIFIC: HUMAN IMMUNODEFICIENCY VIRUS 1;
SOURCE 10 ORGANISM_TAXID: 11676;
SOURCE 11 GENE: ENV;
SOURCE 12 EXPRESSION_SYSTEM: HOMO SAPIENS;
SOURCE 13 EXPRESSION_SYSTEM_COMMON: HUMAN;
SOURCE 14 EXPRESSION_SYSTEM_TAXID: 9606;
SOURCE 15 MOL_ID: 3;
SOURCE 16 ORGANISM_SCIENTIFIC: HOMO SAPIENS;
SOURCE 17 ORGANISM_COMMON: HUMAN;
SOURCE 18 ORGANISM_TAXID: 9606;
SOURCE 19 GENE: CD4;
SOURCE 20 EXPRESSION_SYSTEM: HOMO SAPIENS;
SOURCE 21 EXPRESSION_SYSTEM_COMMON: HUMAN;
SOURCE 22 EXPRESSION_SYSTEM_TAXID: 9606;
SOURCE 23 MOL_ID: 4;
SOURCE 24 ORGANISM_SCIENTIFIC: HOMO SAPIENS;
SOURCE 25 ORGANISM_COMMON: HUMAN;
SOURCE 26 ORGANISM_TAXID: 9606;
SOURCE 27 EXPRESSION_SYSTEM: HOMO SAPIENS;
SOURCE 28 EXPRESSION_SYSTEM_COMMON: HUMAN;
SOURCE 29 EXPRESSION_SYSTEM_TAXID: 9606;
SOURCE 30 MOL_ID: 5;
SOURCE 31 ORGANISM_SCIENTIFIC: HOMO SAPIENS;
SOURCE 32 ORGANISM_COMMON: HUMAN;
SOURCE 33 ORGANISM_TAXID: 9606;
SOURCE 34 EXPRESSION_SYSTEM: HOMO SAPIENS;
SOURCE 35 EXPRESSION_SYSTEM_COMMON: HUMAN;
SOURCE 36 EXPRESSION_SYSTEM_TAXID: 9606;
SOURCE 37 MOL_ID: 6;
SOURCE 38 ORGANISM_SCIENTIFIC: HOMO SAPIENS;
SOURCE 39 ORGANISM_COMMON: HUMAN;
SOURCE 40 ORGANISM_TAXID: 9606;
SOURCE 41 EXPRESSION_SYSTEM: HOMO SAPIENS;
SOURCE 42 EXPRESSION_SYSTEM_COMMON: HUMAN;
SOURCE 43 EXPRESSION_SYSTEM_TAXID: 9606;
SOURCE 44 MOL_ID: 7;
SOURCE 45 ORGANISM_SCIENTIFIC: HOMO SAPIENS;
SOURCE 46 ORGANISM_COMMON: HUMAN;
SOURCE 47 ORGANISM_TAXID: 9606;
SOURCE 48 EXPRESSION_SYSTEM: HOMO SAPIENS;
SOURCE 49 EXPRESSION_SYSTEM_COMMON: HUMAN;
SOURCE 50 EXPRESSION_SYSTEM_TAXID: 9606
KEYWDS HIV-1 ENV, VIRAL PROTEIN
EXPDTA ELECTRON MICROSCOPY
AUTHOR H.WANG,P.J.BJORKMAN
REVDAT 4 29-JUL-20 6CM3 1 COMPND REMARK HETNAM LINK
REVDAT 4 2 1 SITE ATOM
REVDAT 3 18-DEC-19 6CM3 1 CRYST1 SCALE
REVDAT 2 24-OCT-18 6CM3 1 JRNL
REVDAT 1 17-OCT-18 6CM3 0
JRNL AUTH H.WANG,C.O.BARNES,Z.YANG,M.C.NUSSENZWEIG,P.J.BJORKMAN
JRNL TITL PARTIALLY OPEN HIV-1 ENVELOPE STRUCTURES EXHIBIT
JRNL TITL 2 CONFORMATIONAL CHANGES RELEVANT FOR CORECEPTOR BINDING AND
JRNL TITL 3 FUSION.
JRNL REF CELL HOST MICROBE V. 24 579 2018
JRNL REFN ESSN 1934-6069
JRNL PMID 30308160
JRNL DOI 10.1016/J.CHOM.2018.09.003
REMARK 2
REMARK 2 RESOLUTION. 3.54 ANGSTROMS.
REMARK 3
REMARK 3 REFINEMENT.
REMARK 3 SOFTWARE PACKAGES : NULL
REMARK 3 RECONSTRUCTION SCHEMA : NULL
REMARK 3
REMARK 3 EM MAP-MODEL FITTING AND REFINEMENT
REMARK 3 PDB ENTRY : NULL
REMARK 3 REFINEMENT SPACE : NULL
REMARK 3 REFINEMENT PROTOCOL : NULL
REMARK 3 REFINEMENT TARGET : NULL
REMARK 3 OVERALL ANISOTROPIC B VALUE : NULL
REMARK 3
REMARK 3 FITTING PROCEDURE : NULL
REMARK 3
REMARK 3 EM IMAGE RECONSTRUCTION STATISTICS
REMARK 3 NOMINAL PIXEL SIZE (ANGSTROMS) : NULL
REMARK 3 ACTUAL PIXEL SIZE (ANGSTROMS) : NULL
REMARK 3 EFFECTIVE RESOLUTION (ANGSTROMS) : 3.540
REMARK 3 NUMBER OF PARTICLES : 143099
REMARK 3 CTF CORRECTION METHOD : PHASE FLIPPING AND AMPLITUDE
REMARK 3 CORRECTION
REMARK 3
REMARK 3 EM RECONSTRUCTION MAGNIFICATION CALIBRATION: NULL
REMARK 3
REMARK 3 OTHER DETAILS: NULL
REMARK 4
REMARK 4 6CM3 COMPLIES WITH FORMAT V. 3.30, 13-JUL-11
REMARK 100
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 05-MAR-18.
REMARK 100 THE DEPOSITION ID IS D_1000232981.
REMARK 245
REMARK 245 EXPERIMENTAL DETAILS
REMARK 245 RECONSTRUCTION METHOD : SINGLE PARTICLE
REMARK 245 SPECIMEN TYPE : NULL
REMARK 245
REMARK 245 ELECTRON MICROSCOPE SAMPLE
REMARK 245 SAMPLE TYPE : PARTICLE
REMARK 245 PARTICLE TYPE : POINT
REMARK 245 NAME OF SAMPLE : BG505 SOSIP IN COMPLEX WITH
REMARK 245 SCD4, 17B, 8ANC195
REMARK 245 SAMPLE CONCENTRATION (MG ML-1) : NULL
REMARK 245 SAMPLE SUPPORT DETAILS : NULL
REMARK 245 SAMPLE VITRIFICATION DETAILS : NULL
REMARK 245 SAMPLE BUFFER : NULL
REMARK 245 PH : 8.00
REMARK 245 SAMPLE DETAILS : NULL
REMARK 245
REMARK 245 DATA ACQUISITION
REMARK 245 DATE OF EXPERIMENT : NULL
REMARK 245 NUMBER OF MICROGRAPHS-IMAGES : NULL
REMARK 245 TEMPERATURE (KELVIN) : NULL
REMARK 245 MICROSCOPE MODEL : FEI TITAN KRIOS
REMARK 245 DETECTOR TYPE : GATAN K2 SUMMIT (4K X 4K)
REMARK 245 MINIMUM DEFOCUS (NM) : NULL
REMARK 245 MAXIMUM DEFOCUS (NM) : NULL
REMARK 245 MINIMUM TILT ANGLE (DEGREES) : NULL
REMARK 245 MAXIMUM TILT ANGLE (DEGREES) : NULL
REMARK 245 NOMINAL CS : NULL
REMARK 245 IMAGING MODE : BRIGHT FIELD
REMARK 245 ELECTRON DOSE (ELECTRONS NM**-2) : 87.50
REMARK 245 ILLUMINATION MODE : FLOOD BEAM
REMARK 245 NOMINAL MAGNIFICATION : NULL
REMARK 245 CALIBRATED MAGNIFICATION : NULL
REMARK 245 SOURCE : FIELD EMISSION GUN
REMARK 245 ACCELERATION VOLTAGE (KV) : 300
REMARK 245 IMAGING DETAILS : NULL
REMARK 247
REMARK 247 ELECTRON MICROSCOPY
REMARK 247 THE COORDINATES IN THIS ENTRY WERE GENERATED FROM ELECTRON
REMARK 247 MICROSCOPY DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE
REMARK 247 THAT CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES
REMARK 247 ON THESE RECORDS ARE MEANINGLESS EXCEPT FOR THE CALCULATION
REMARK 247 OF THE STRUCTURE FACTORS.
REMARK 300
REMARK 300 BIOMOLECULE: 1
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON
REMARK 300 BURIED SURFACE AREA.
REMARK 350
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS
REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.
REMARK 350
REMARK 350 BIOMOLECULE: 1
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: 21-MERIC
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B, C, D, E, F, G, H, I, J,
REMARK 350 AND CHAINS: K, L, M, N, O, P, Q, R, S,
REMARK 350 AND CHAINS: T, U, V, W, X, Y, Z, a, b, c,
REMARK 350 AND CHAINS: d, e, f, g, h, i, j
REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000
REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000
REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000
REMARK 465
REMARK 465 MISSING RESIDUES
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)
REMARK 465
REMARK 465 M RES C SSSEQI
REMARK 465 ALA A 512
REMARK 465 VAL A 513
REMARK 465 GLY A 514
REMARK 465 ILE A 515
REMARK 465 SER A 546
REMARK 465 GLY A 547
REMARK 465 ILE A 548
REMARK 465 VAL A 549
REMARK 465 GLN A 550
REMARK 465 GLN A 551
REMARK 465 GLN A 552
REMARK 465 SER A 553
REMARK 465 ASN A 554
REMARK 465 LEU A 555
REMARK 465 LEU A 556
REMARK 465 ARG A 557
REMARK 465 ALA A 558
REMARK 465 PRO A 559
REMARK 465 GLU A 560
REMARK 465 ALA A 561
REMARK 465 GLN A 562
REMARK 465 GLN A 563
REMARK 465 GLN A 652
REMARK 465 GLN A 653
REMARK 465 GLU A 654
REMARK 465 LYS A 655
REMARK 465 ASN A 656
REMARK 465 GLU A 657
REMARK 465 GLN A 658
REMARK 465 ASP A 659
REMARK 465 LEU A 660
REMARK 465 LEU A 661
REMARK 465 ALA A 662
REMARK 465 LEU A 663
REMARK 465 ASP A 664
REMARK 465 ALA B 512
REMARK 465 VAL B 513
REMARK 465 GLY B 514
REMARK 465 ILE B 515
REMARK 465 SER B 546
REMARK 465 GLY B 547
REMARK 465 ILE B 548
REMARK 465 VAL B 549
REMARK 465 GLN B 550
REMARK 465 GLN B 551
REMARK 465 GLN B 552
REMARK 465 SER B 553
REMARK 465 ASN B 554
REMARK 465 LEU B 555
REMARK 465 LEU B 556
REMARK 465 ARG B 557
REMARK 465 ALA B 558
REMARK 465 PRO B 559
REMARK 465 GLU B 560
REMARK 465 ALA B 561
REMARK 465 GLN B 562
REMARK 465 GLN B 563
REMARK 465 GLN B 652
REMARK 465 GLN B 653
REMARK 465 GLU B 654
REMARK 465 LYS B 655
REMARK 465 ASN B 656
REMARK 465 GLU B 657
REMARK 465 GLN B 658
REMARK 465 ASP B 659
REMARK 465 LEU B 660
REMARK 465 LEU B 661
REMARK 465 ALA B 662
REMARK 465 LEU B 663
REMARK 465 ASP B 664
REMARK 465 ALA C 512
REMARK 465 VAL C 513
REMARK 465 GLY C 514
REMARK 465 ILE C 515
REMARK 465 SER C 546
REMARK 465 GLY C 547
REMARK 465 ILE C 548
REMARK 465 VAL C 549
REMARK 465 GLN C 550
REMARK 465 GLN C 551
REMARK 465 GLN C 552
REMARK 465 SER C 553
REMARK 465 ASN C 554
REMARK 465 LEU C 555
REMARK 465 LEU C 556
REMARK 465 ARG C 557
REMARK 465 ALA C 558
REMARK 465 PRO C 559
REMARK 465 GLU C 560
REMARK 465 ALA C 561
REMARK 465 GLN C 562
REMARK 465 GLN C 563
REMARK 465 GLN C 652
REMARK 465 GLN C 653
REMARK 465 GLU C 654
REMARK 465 LYS C 655
REMARK 465 ASN C 656
REMARK 465 GLU C 657
REMARK 465 GLN C 658
REMARK 465 ASP C 659
REMARK 465 LEU C 660
REMARK 465 LEU C 661
REMARK 465 ALA C 662
REMARK 465 LEU C 663
REMARK 465 ASP C 664
REMARK 465 ALA D 31
REMARK 465 GLU D 32
REMARK 465 LEU D 129
REMARK 465 GLN D 130
REMARK 465 CYS D 131
REMARK 465 THR D 132
REMARK 465 ASN D 133
REMARK 465 VAL D 134
REMARK 465 THR D 135
REMARK 465 ASN D 136
REMARK 465 ASN D 137
REMARK 465 ILE D 138
REMARK 465 THR D 139
REMARK 465 ASP D 140
REMARK 465 ASP D 141
REMARK 465 MET D 142
REMARK 465 ARG D 143
REMARK 465 GLY D 144
REMARK 465 GLU D 145
REMARK 465 LEU D 146
REMARK 465 LYS D 147
REMARK 465 ASN D 148
REMARK 465 CYS D 149
REMARK 465 SER D 150
REMARK 465 PHE D 151
REMARK 465 ASN D 152
REMARK 465 MET D 153
REMARK 465 THR D 154
REMARK 465 THR D 155
REMARK 465 GLU D 156
REMARK 465 LEU D 157
REMARK 465 ARG D 158
REMARK 465 ASP D 159
REMARK 465 LYS D 160
REMARK 465 LYS D 161
REMARK 465 GLN D 162
REMARK 465 LYS D 163
REMARK 465 VAL D 164
REMARK 465 TYR D 165
REMARK 465 SER D 166
REMARK 465 LEU D 167
REMARK 465 PHE D 168
REMARK 465 TYR D 169
REMARK 465 ARG D 170
REMARK 465 LEU D 171
REMARK 465 ASP D 172
REMARK 465 VAL D 173
REMARK 465 VAL D 174
REMARK 465 GLN D 175
REMARK 465 ILE D 176
REMARK 465 ASN D 177
REMARK 465 GLU D 178
REMARK 465 ASN D 179
REMARK 465 GLN D 180
REMARK 465 GLY D 181
REMARK 465 ASN D 182
REMARK 465 ARG D 183
REMARK 465 SER D 184
REMARK 465 ASN D 185
REMARK 465 ASN D 186
REMARK 465 SER D 187
REMARK 465 ASN D 188
REMARK 465 ASN D 302
REMARK 465 ASN D 303
REMARK 465 THR D 304
REMARK 465 ARG D 305
REMARK 465 LYS D 306
REMARK 465 SER D 307
REMARK 465 ILE D 308
REMARK 465 ARG D 309
REMARK 465 ILE D 310
REMARK 465 GLY D 311
REMARK 465 PRO D 312
REMARK 465 GLY D 313
REMARK 465 GLN D 314
REMARK 465 ALA D 315
REMARK 465 PHE D 316
REMARK 465 TYR D 317
REMARK 465 ALA D 318
REMARK 465 THR D 319
REMARK 465 GLY D 320
REMARK 465 ASP D 321
REMARK 465 ILE D 322
REMARK 465 ASN D 399
REMARK 465 THR D 400
REMARK 465 SER D 401
REMARK 465 VAL D 402
REMARK 465 GLN D 403
REMARK 465 GLY D 404
REMARK 465 SER D 405
REMARK 465 ASN D 406
REMARK 465 SER D 407
REMARK 465 THR D 408
REMARK 465 GLY D 409
REMARK 465 SER D 410
REMARK 465 ASN D 411
REMARK 465 ASN D 462
REMARK 465 LYS D 502
REMARK 465 ARG D 503
REMARK 465 ARG D 504
REMARK 465 VAL D 505
REMARK 465 VAL D 506
REMARK 465 GLY D 507
REMARK 465 ARG D 508
REMARK 465 ARG D 509
REMARK 465 ARG D 510
REMARK 465 ARG D 511
REMARK 465 ARG D 512
REMARK 465 ARG D 513
REMARK 465 ALA E 31
REMARK 465 GLU E 32
REMARK 465 LEU E 129
REMARK 465 GLN E 130
REMARK 465 CYS E 131
REMARK 465 THR E 132
REMARK 465 ASN E 133
REMARK 465 VAL E 134
REMARK 465 THR E 135
REMARK 465 ASN E 136
REMARK 465 ASN E 137
REMARK 465 ILE E 138
REMARK 465 THR E 139
REMARK 465 ASP E 140
REMARK 465 ASP E 141
REMARK 465 MET E 142
REMARK 465 ARG E 143
REMARK 465 GLY E 144
REMARK 465 GLU E 145
REMARK 465 LEU E 146
REMARK 465 LYS E 147
REMARK 465 ASN E 148
REMARK 465 CYS E 149
REMARK 465 SER E 150
REMARK 465 PHE E 151
REMARK 465 ASN E 152
REMARK 465 MET E 153
REMARK 465 THR E 154
REMARK 465 THR E 155
REMARK 465 GLU E 156
REMARK 465 LEU E 157
REMARK 465 ARG E 158
REMARK 465 ASP E 159
REMARK 465 LYS E 160
REMARK 465 LYS E 161
REMARK 465 GLN E 162
REMARK 465 LYS E 163
REMARK 465 VAL E 164
REMARK 465 TYR E 165
REMARK 465 SER E 166
REMARK 465 LEU E 167
REMARK 465 PHE E 168
REMARK 465 TYR E 169
REMARK 465 ARG E 170
REMARK 465 LEU E 171
REMARK 465 ASP E 172
REMARK 465 VAL E 173
REMARK 465 VAL E 174
REMARK 465 GLN E 175
REMARK 465 ILE E 176
REMARK 465 ASN E 177
REMARK 465 GLU E 178
REMARK 465 ASN E 179
REMARK 465 GLN E 180
REMARK 465 GLY E 181
REMARK 465 ASN E 182
REMARK 465 ARG E 183
REMARK 465 SER E 184
REMARK 465 ASN E 185
REMARK 465 ASN E 186
REMARK 465 SER E 187
REMARK 465 ASN E 188
REMARK 465 ASN E 302
REMARK 465 ASN E 303
REMARK 465 THR E 304
REMARK 465 ARG E 305
REMARK 465 LYS E 306
REMARK 465 SER E 307
REMARK 465 ILE E 308
REMARK 465 ARG E 309
REMARK 465 ILE E 310
REMARK 465 GLY E 311
REMARK 465 PRO E 312
REMARK 465 GLY E 313
REMARK 465 GLN E 314
REMARK 465 ALA E 315
REMARK 465 PHE E 316
REMARK 465 TYR E 317
REMARK 465 ALA E 318
REMARK 465 THR E 319
REMARK 465 GLY E 320
REMARK 465 ASP E 321
REMARK 465 ILE E 322
REMARK 465 ASN E 399
REMARK 465 THR E 400
REMARK 465 SER E 401
REMARK 465 VAL E 402
REMARK 465 GLN E 403
REMARK 465 GLY E 404
REMARK 465 SER E 405
REMARK 465 ASN E 406
REMARK 465 SER E 407
REMARK 465 THR E 408
REMARK 465 GLY E 409
REMARK 465 SER E 410
REMARK 465 ASN E 411
REMARK 465 ASN E 462
REMARK 465 LYS E 502
REMARK 465 ARG E 503
REMARK 465 ARG E 504
REMARK 465 VAL E 505
REMARK 465 VAL E 506
REMARK 465 GLY E 507
REMARK 465 ARG E 508
REMARK 465 ARG E 509
REMARK 465 ARG E 510
REMARK 465 ARG E 511
REMARK 465 ARG E 512
REMARK 465 ARG E 513
REMARK 465 ALA F 31
REMARK 465 GLU F 32
REMARK 465 LEU F 129
REMARK 465 GLN F 130
REMARK 465 CYS F 131
REMARK 465 THR F 132
REMARK 465 ASN F 133
REMARK 465 VAL F 134
REMARK 465 THR F 135
REMARK 465 ASN F 136
REMARK 465 ASN F 137
REMARK 465 ILE F 138
REMARK 465 THR F 139
REMARK 465 ASP F 140
REMARK 465 ASP F 141
REMARK 465 MET F 142
REMARK 465 ARG F 143
REMARK 465 GLY F 144
REMARK 465 GLU F 145
REMARK 465 LEU F 146
REMARK 465 LYS F 147
REMARK 465 ASN F 148
REMARK 465 CYS F 149
REMARK 465 SER F 150
REMARK 465 PHE F 151
REMARK 465 ASN F 152
REMARK 465 MET F 153
REMARK 465 THR F 154
REMARK 465 THR F 155
REMARK 465 GLU F 156
REMARK 465 LEU F 157
REMARK 465 ARG F 158
REMARK 465 ASP F 159
REMARK 465 LYS F 160
REMARK 465 LYS F 161
REMARK 465 GLN F 162
REMARK 465 LYS F 163
REMARK 465 VAL F 164
REMARK 465 TYR F 165
REMARK 465 SER F 166
REMARK 465 LEU F 167
REMARK 465 PHE F 168
REMARK 465 TYR F 169
REMARK 465 ARG F 170
REMARK 465 LEU F 171
REMARK 465 ASP F 172
REMARK 465 VAL F 173
REMARK 465 VAL F 174
REMARK 465 GLN F 175
REMARK 465 ILE F 176
REMARK 465 ASN F 177
REMARK 465 GLU F 178
REMARK 465 ASN F 179
REMARK 465 GLN F 180
REMARK 465 GLY F 181
REMARK 465 ASN F 182
REMARK 465 ARG F 183
REMARK 465 SER F 184
REMARK 465 ASN F 185
REMARK 465 ASN F 186
REMARK 465 SER F 187
REMARK 465 ASN F 188
REMARK 465 ASN F 302
REMARK 465 ASN F 303
REMARK 465 THR F 304
REMARK 465 ARG F 305
REMARK 465 LYS F 306
REMARK 465 SER F 307
REMARK 465 ILE F 308
REMARK 465 ARG F 309
REMARK 465 ILE F 310
REMARK 465 GLY F 311
REMARK 465 PRO F 312
REMARK 465 GLY F 313
REMARK 465 GLN F 314
REMARK 465 ALA F 315
REMARK 465 PHE F 316
REMARK 465 TYR F 317
REMARK 465 ALA F 318
REMARK 465 THR F 319
REMARK 465 GLY F 320
REMARK 465 ASP F 321
REMARK 465 ILE F 322
REMARK 465 ASN F 399
REMARK 465 THR F 400
REMARK 465 SER F 401
REMARK 465 VAL F 402
REMARK 465 GLN F 403
REMARK 465 GLY F 404
REMARK 465 SER F 405
REMARK 465 ASN F 406
REMARK 465 SER F 407
REMARK 465 THR F 408
REMARK 465 GLY F 409
REMARK 465 SER F 410
REMARK 465 ASN F 411
REMARK 465 ASN F 462
REMARK 465 LYS F 502
REMARK 465 ARG F 503
REMARK 465 ARG F 504
REMARK 465 VAL F 505
REMARK 465 VAL F 506
REMARK 465 GLY F 507
REMARK 465 ARG F 508
REMARK 465 ARG F 509
REMARK 465 ARG F 510
REMARK 465 ARG F 511
REMARK 465 ARG F 512
REMARK 465 ARG F 513
REMARK 465 PHE G 98
REMARK 465 GLY G 99
REMARK 465 LEU G 100
REMARK 465 THR G 101
REMARK 465 ALA G 102
REMARK 465 ASN G 103
REMARK 465 SER G 104
REMARK 465 ASP G 105
REMARK 465 THR G 106
REMARK 465 HIS G 107
REMARK 465 LEU G 108
REMARK 465 LEU G 109
REMARK 465 GLN G 110
REMARK 465 GLY G 111
REMARK 465 GLN G 112
REMARK 465 SER G 113
REMARK 465 LEU G 114
REMARK 465 THR G 115
REMARK 465 LEU G 116
REMARK 465 THR G 117
REMARK 465 LEU G 118
REMARK 465 GLU G 119
REMARK 465 SER G 120
REMARK 465 PRO G 121
REMARK 465 PRO G 122
REMARK 465 GLY G 123
REMARK 465 SER G 124
REMARK 465 SER G 125
REMARK 465 PRO G 126
REMARK 465 SER G 127
REMARK 465 VAL G 128
REMARK 465 GLN G 129
REMARK 465 CYS G 130
REMARK 465 ARG G 131
REMARK 465 SER G 132
REMARK 465 PRO G 133
REMARK 465 ARG G 134
REMARK 465 GLY G 135
REMARK 465 LYS G 136
REMARK 465 ASN G 137
REMARK 465 ILE G 138
REMARK 465 GLN G 139
REMARK 465 GLY G 140
REMARK 465 GLY G 141
REMARK 465 LYS G 142
REMARK 465 THR G 143
REMARK 465 LEU G 144
REMARK 465 SER G 145
REMARK 465 VAL G 146
REMARK 465 SER G 147
REMARK 465 GLN G 148
REMARK 465 LEU G 149
REMARK 465 GLU G 150
REMARK 465 LEU G 151
REMARK 465 GLN G 152
REMARK 465 ASP G 153
REMARK 465 SER G 154
REMARK 465 GLY G 155
REMARK 465 THR G 156
REMARK 465 TRP G 157
REMARK 465 THR G 158
REMARK 465 CYS G 159
REMARK 465 THR G 160
REMARK 465 VAL G 161
REMARK 465 LEU G 162
REMARK 465 GLN G 163
REMARK 465 ASN G 164
REMARK 465 GLN G 165
REMARK 465 LYS G 166
REMARK 465 LYS G 167
REMARK 465 VAL G 168
REMARK 465 GLU G 169
REMARK 465 PHE G 170
REMARK 465 LYS G 171
REMARK 465 ILE G 172
REMARK 465 ASP G 173
REMARK 465 ILE G 174
REMARK 465 VAL G 175
REMARK 465 VAL G 176
REMARK 465 LEU G 177
REMARK 465 ALA G 178
REMARK 465 PHE G 179
REMARK 465 GLN G 180
REMARK 465 LYS G 181
REMARK 465 ALA G 182
REMARK 465 ILE G 183
REMARK 465 ASP G 184
REMARK 465 GLY G 185
REMARK 465 ARG G 186
REMARK 465 HIS G 187
REMARK 465 HIS G 188
REMARK 465 HIS G 189
REMARK 465 HIS G 190
REMARK 465 HIS G 191
REMARK 465 HIS G 192
REMARK 465 PHE H 98
REMARK 465 GLY H 99
REMARK 465 LEU H 100
REMARK 465 THR H 101
REMARK 465 ALA H 102
REMARK 465 ASN H 103
REMARK 465 SER H 104
REMARK 465 ASP H 105
REMARK 465 THR H 106
REMARK 465 HIS H 107
REMARK 465 LEU H 108
REMARK 465 LEU H 109
REMARK 465 GLN H 110
REMARK 465 GLY H 111
REMARK 465 GLN H 112
REMARK 465 SER H 113
REMARK 465 LEU H 114
REMARK 465 THR H 115
REMARK 465 LEU H 116
REMARK 465 THR H 117
REMARK 465 LEU H 118
REMARK 465 GLU H 119
REMARK 465 SER H 120
REMARK 465 PRO H 121
REMARK 465 PRO H 122
REMARK 465 GLY H 123
REMARK 465 SER H 124
REMARK 465 SER H 125
REMARK 465 PRO H 126
REMARK 465 SER H 127
REMARK 465 VAL H 128
REMARK 465 GLN H 129
REMARK 465 CYS H 130
REMARK 465 ARG H 131
REMARK 465 SER H 132
REMARK 465 PRO H 133
REMARK 465 ARG H 134
REMARK 465 GLY H 135
REMARK 465 LYS H 136
REMARK 465 ASN H 137
REMARK 465 ILE H 138
REMARK 465 GLN H 139
REMARK 465 GLY H 140
REMARK 465 GLY H 141
REMARK 465 LYS H 142
REMARK 465 THR H 143
REMARK 465 LEU H 144
REMARK 465 SER H 145
REMARK 465 VAL H 146
REMARK 465 SER H 147
REMARK 465 GLN H 148
REMARK 465 LEU H 149
REMARK 465 GLU H 150
REMARK 465 LEU H 151
REMARK 465 GLN H 152
REMARK 465 ASP H 153
REMARK 465 SER H 154
REMARK 465 GLY H 155
REMARK 465 THR H 156
REMARK 465 TRP H 157
REMARK 465 THR H 158
REMARK 465 CYS H 159
REMARK 465 THR H 160
REMARK 465 VAL H 161
REMARK 465 LEU H 162
REMARK 465 GLN H 163
REMARK 465 ASN H 164
REMARK 465 GLN H 165
REMARK 465 LYS H 166
REMARK 465 LYS H 167
REMARK 465 VAL H 168
REMARK 465 GLU H 169
REMARK 465 PHE H 170
REMARK 465 LYS H 171
REMARK 465 ILE H 172
REMARK 465 ASP H 173
REMARK 465 ILE H 174
REMARK 465 VAL H 175
REMARK 465 VAL H 176
REMARK 465 LEU H 177
REMARK 465 ALA H 178
REMARK 465 PHE H 179
REMARK 465 GLN H 180
REMARK 465 LYS H 181
REMARK 465 ALA H 182
REMARK 465 ILE H 183
REMARK 465 ASP H 184
REMARK 465 GLY H 185
REMARK 465 ARG H 186
REMARK 465 HIS H 187
REMARK 465 HIS H 188
REMARK 465 HIS H 189
REMARK 465 HIS H 190
REMARK 465 HIS H 191
REMARK 465 HIS H 192
REMARK 465 PHE I 98
REMARK 465 GLY I 99
REMARK 465 LEU I 100
REMARK 465 THR I 101
REMARK 465 ALA I 102
REMARK 465 ASN I 103
REMARK 465 SER I 104
REMARK 465 ASP I 105
REMARK 465 THR I 106
REMARK 465 HIS I 107
REMARK 465 LEU I 108
REMARK 465 LEU I 109
REMARK 465 GLN I 110
REMARK 465 GLY I 111
REMARK 465 GLN I 112
REMARK 465 SER I 113
REMARK 465 LEU I 114
REMARK 465 THR I 115
REMARK 465 LEU I 116
REMARK 465 THR I 117
REMARK 465 LEU I 118
REMARK 465 GLU I 119
REMARK 465 SER I 120
REMARK 465 PRO I 121
REMARK 465 PRO I 122
REMARK 465 GLY I 123
REMARK 465 SER I 124
REMARK 465 SER I 125
REMARK 465 PRO I 126
REMARK 465 SER I 127
REMARK 465 VAL I 128
REMARK 465 GLN I 129
REMARK 465 CYS I 130
REMARK 465 ARG I 131
REMARK 465 SER I 132
REMARK 465 PRO I 133
REMARK 465 ARG I 134
REMARK 465 GLY I 135
REMARK 465 LYS I 136
REMARK 465 ASN I 137
REMARK 465 ILE I 138
REMARK 465 GLN I 139
REMARK 465 GLY I 140
REMARK 465 GLY I 141
REMARK 465 LYS I 142
REMARK 465 THR I 143
REMARK 465 LEU I 144
REMARK 465 SER I 145
REMARK 465 VAL I 146
REMARK 465 SER I 147
REMARK 465 GLN I 148
REMARK 465 LEU I 149
REMARK 465 GLU I 150
REMARK 465 LEU I 151
REMARK 465 GLN I 152
REMARK 465 ASP I 153
REMARK 465 SER I 154
REMARK 465 GLY I 155
REMARK 465 THR I 156
REMARK 465 TRP I 157
REMARK 465 THR I 158
REMARK 465 CYS I 159
REMARK 465 THR I 160
REMARK 465 VAL I 161
REMARK 465 LEU I 162
REMARK 465 GLN I 163
REMARK 465 ASN I 164
REMARK 465 GLN I 165
REMARK 465 LYS I 166
REMARK 465 LYS I 167
REMARK 465 VAL I 168
REMARK 465 GLU I 169
REMARK 465 PHE I 170
REMARK 465 LYS I 171
REMARK 465 ILE I 172
REMARK 465 ASP I 173
REMARK 465 ILE I 174
REMARK 465 VAL I 175
REMARK 465 VAL I 176
REMARK 465 LEU I 177
REMARK 465 ALA I 178
REMARK 465 PHE I 179
REMARK 465 GLN I 180
REMARK 465 LYS I 181
REMARK 465 ALA I 182
REMARK 465 ILE I 183
REMARK 465 ASP I 184
REMARK 465 GLY I 185
REMARK 465 ARG I 186
REMARK 465 HIS I 187
REMARK 465 HIS I 188
REMARK 465 HIS I 189
REMARK 465 HIS I 190
REMARK 465 HIS I 191
REMARK 465 HIS I 192
REMARK 465 VAL J 3
REMARK 465 LYS J 109
REMARK 465 ARG J 110
REMARK 465 THR J 111
REMARK 465 VAL J 112
REMARK 465 ALA J 113
REMARK 465 ALA J 114
REMARK 465 PRO J 115
REMARK 465 SER J 116
REMARK 465 VAL J 117
REMARK 465 PHE J 118
REMARK 465 ILE J 119
REMARK 465 PHE J 120
REMARK 465 PRO J 121
REMARK 465 PRO J 122
REMARK 465 SER J 123
REMARK 465 ASP J 124
REMARK 465 GLU J 125
REMARK 465 GLN J 126
REMARK 465 LEU J 127
REMARK 465 LYS J 128
REMARK 465 SER J 129
REMARK 465 GLY J 130
REMARK 465 THR J 131
REMARK 465 ALA J 132
REMARK 465 SER J 133
REMARK 465 VAL J 134
REMARK 465 VAL J 135
REMARK 465 CYS J 136
REMARK 465 LEU J 137
REMARK 465 LEU J 138
REMARK 465 ASN J 139
REMARK 465 ASN J 140
REMARK 465 PHE J 141
REMARK 465 TYR J 142
REMARK 465 PRO J 143
REMARK 465 ARG J 144
REMARK 465 GLU J 145
REMARK 465 ALA J 146
REMARK 465 LYS J 147
REMARK 465 VAL J 148
REMARK 465 GLN J 149
REMARK 465 TRP J 150
REMARK 465 LYS J 151
REMARK 465 VAL J 152
REMARK 465 ASP J 153
REMARK 465 ASN J 154
REMARK 465 ALA J 155
REMARK 465 LEU J 156
REMARK 465 GLN J 157
REMARK 465 SER J 158
REMARK 465 GLY J 159
REMARK 465 ASN J 160
REMARK 465 SER J 161
REMARK 465 GLN J 162
REMARK 465 GLU J 163
REMARK 465 SER J 164
REMARK 465 VAL J 165
REMARK 465 THR J 166
REMARK 465 GLU J 167
REMARK 465 GLN J 168
REMARK 465 ASP J 169
REMARK 465 SER J 170
REMARK 465 LYS J 171
REMARK 465 ASP J 172
REMARK 465 SER J 173
REMARK 465 THR J 174
REMARK 465 TYR J 175
REMARK 465 SER J 176
REMARK 465 LEU J 177
REMARK 465 SER J 178
REMARK 465 SER J 179
REMARK 465 THR J 180
REMARK 465 LEU J 181
REMARK 465 THR J 182
REMARK 465 LEU J 183
REMARK 465 SER J 184
REMARK 465 LYS J 185
REMARK 465 ALA J 186
REMARK 465 ASP J 187
REMARK 465 TYR J 188
REMARK 465 GLU J 189
REMARK 465 LYS J 190
REMARK 465 HIS J 191
REMARK 465 LYS J 192
REMARK 465 VAL J 193
REMARK 465 TYR J 194
REMARK 465 ALA J 195
REMARK 465 CYS J 196
REMARK 465 GLU J 197
REMARK 465 VAL J 198
REMARK 465 THR J 199
REMARK 465 HIS J 200
REMARK 465 GLN J 201
REMARK 465 GLY J 202
REMARK 465 LEU J 203
REMARK 465 SER J 204
REMARK 465 SER J 205
REMARK 465 PRO J 206
REMARK 465 VAL J 207
REMARK 465 THR J 208
REMARK 465 LYS J 209
REMARK 465 SER J 210
REMARK 465 PHE J 211
REMARK 465 ASN J 212
REMARK 465 ARG J 213
REMARK 465 GLY J 214
REMARK 465 SER K 128
REMARK 465 ALA K 129
REMARK 465 SER K 130
REMARK 465 THR K 131
REMARK 465 LYS K 132
REMARK 465 GLY K 133
REMARK 465 PRO K 134
REMARK 465 SER K 135
REMARK 465 VAL K 136
REMARK 465 PHE K 137
REMARK 465 PRO K 138
REMARK 465 LEU K 139
REMARK 465 ALA K 140
REMARK 465 PRO K 141
REMARK 465 SER K 142
REMARK 465 SER K 143
REMARK 465 LYS K 144
REMARK 465 SER K 145
REMARK 465 THR K 146
REMARK 465 SER K 147
REMARK 465 GLY K 148
REMARK 465 GLY K 149
REMARK 465 THR K 150
REMARK 465 ALA K 151
REMARK 465 ALA K 152
REMARK 465 LEU K 153
REMARK 465 GLY K 154
REMARK 465 CYS K 155
REMARK 465 LEU K 156
REMARK 465 VAL K 157
REMARK 465 LYS K 158
REMARK 465 ASP K 159
REMARK 465 TYR K 160
REMARK 465 PHE K 161
REMARK 465 PRO K 162
REMARK 465 GLU K 163
REMARK 465 PRO K 164
REMARK 465 VAL K 165
REMARK 465 THR K 166
REMARK 465 VAL K 167
REMARK 465 SER K 168
REMARK 465 TRP K 169
REMARK 465 ASN K 170
REMARK 465 SER K 171
REMARK 465 GLY K 172
REMARK 465 ALA K 173
REMARK 465 LEU K 174
REMARK 465 THR K 175
REMARK 465 SER K 176
REMARK 465 GLY K 177
REMARK 465 VAL K 178
REMARK 465 HIS K 179
REMARK 465 THR K 180
REMARK 465 PHE K 181
REMARK 465 PRO K 182
REMARK 465 ALA K 183
REMARK 465 VAL K 184
REMARK 465 LEU K 185
REMARK 465 GLN K 186
REMARK 465 SER K 187
REMARK 465 SER K 188
REMARK 465 GLY K 189
REMARK 465 LEU K 190
REMARK 465 TYR K 191
REMARK 465 SER K 192
REMARK 465 LEU K 193
REMARK 465 SER K 194
REMARK 465 SER K 195
REMARK 465 VAL K 196
REMARK 465 VAL K 197
REMARK 465 THR K 198
REMARK 465 VAL K 199
REMARK 465 PRO K 200
REMARK 465 SER K 201
REMARK 465 SER K 202
REMARK 465 SER K 203
REMARK 465 LEU K 204
REMARK 465 GLY K 205
REMARK 465 THR K 206
REMARK 465 GLN K 207
REMARK 465 THR K 208
REMARK 465 TYR K 209
REMARK 465 ILE K 210
REMARK 465 CYS K 211
REMARK 465 ASN K 212
REMARK 465 VAL K 213
REMARK 465 ASN K 214
REMARK 465 HIS K 215
REMARK 465 LYS K 216
REMARK 465 PRO K 217
REMARK 465 SER K 218
REMARK 465 ASN K 219
REMARK 465 THR K 220
REMARK 465 LYS K 221
REMARK 465 VAL K 222
REMARK 465 ASP K 223
REMARK 465 LYS K 224
REMARK 465 LYS K 225
REMARK 465 VAL K 226
REMARK 465 GLU K 227
REMARK 465 PRO K 228
REMARK 465 LYS K 229
REMARK 465 VAL L 3
REMARK 465 LYS L 109
REMARK 465 ARG L 110
REMARK 465 THR L 111
REMARK 465 VAL L 112
REMARK 465 ALA L 113
REMARK 465 ALA L 114
REMARK 465 PRO L 115
REMARK 465 SER L 116
REMARK 465 VAL L 117
REMARK 465 PHE L 118
REMARK 465 ILE L 119
REMARK 465 PHE L 120
REMARK 465 PRO L 121
REMARK 465 PRO L 122
REMARK 465 SER L 123
REMARK 465 ASP L 124
REMARK 465 GLU L 125
REMARK 465 GLN L 126
REMARK 465 LEU L 127
REMARK 465 LYS L 128
REMARK 465 SER L 129
REMARK 465 GLY L 130
REMARK 465 THR L 131
REMARK 465 ALA L 132
REMARK 465 SER L 133
REMARK 465 VAL L 134
REMARK 465 VAL L 135
REMARK 465 CYS L 136
REMARK 465 LEU L 137
REMARK 465 LEU L 138
REMARK 465 ASN L 139
REMARK 465 ASN L 140
REMARK 465 PHE L 141
REMARK 465 TYR L 142
REMARK 465 PRO L 143
REMARK 465 ARG L 144
REMARK 465 GLU L 145
REMARK 465 ALA L 146
REMARK 465 LYS L 147
REMARK 465 VAL L 148
REMARK 465 GLN L 149
REMARK 465 TRP L 150
REMARK 465 LYS L 151
REMARK 465 VAL L 152
REMARK 465 ASP L 153
REMARK 465 ASN L 154
REMARK 465 ALA L 155
REMARK 465 LEU L 156
REMARK 465 GLN L 157
REMARK 465 SER L 158
REMARK 465 GLY L 159
REMARK 465 ASN L 160
REMARK 465 SER L 161
REMARK 465 GLN L 162
REMARK 465 GLU L 163
REMARK 465 SER L 164
REMARK 465 VAL L 165
REMARK 465 THR L 166
REMARK 465 GLU L 167
REMARK 465 GLN L 168
REMARK 465 ASP L 169
REMARK 465 SER L 170
REMARK 465 LYS L 171
REMARK 465 ASP L 172
REMARK 465 SER L 173
REMARK 465 THR L 174
REMARK 465 TYR L 175
REMARK 465 SER L 176
REMARK 465 LEU L 177
REMARK 465 SER L 178
REMARK 465 SER L 179
REMARK 465 THR L 180
REMARK 465 LEU L 181
REMARK 465 THR L 182
REMARK 465 LEU L 183
REMARK 465 SER L 184
REMARK 465 LYS L 185
REMARK 465 ALA L 186
REMARK 465 ASP L 187
REMARK 465 TYR L 188
REMARK 465 GLU L 189
REMARK 465 LYS L 190
REMARK 465 HIS L 191
REMARK 465 LYS L 192
REMARK 465 VAL L 193
REMARK 465 TYR L 194
REMARK 465 ALA L 195
REMARK 465 CYS L 196
REMARK 465 GLU L 197
REMARK 465 VAL L 198
REMARK 465 THR L 199
REMARK 465 HIS L 200
REMARK 465 GLN L 201
REMARK 465 GLY L 202
REMARK 465 LEU L 203
REMARK 465 SER L 204
REMARK 465 SER L 205
REMARK 465 PRO L 206
REMARK 465 VAL L 207
REMARK 465 THR L 208
REMARK 465 LYS L 209
REMARK 465 SER L 210
REMARK 465 PHE L 211
REMARK 465 ASN L 212
REMARK 465 ARG L 213
REMARK 465 GLY L 214
REMARK 465 SER M 128
REMARK 465 ALA M 129
REMARK 465 SER M 130
REMARK 465 THR M 131
REMARK 465 LYS M 132
REMARK 465 GLY M 133
REMARK 465 PRO M 134
REMARK 465 SER M 135
REMARK 465 VAL M 136
REMARK 465 PHE M 137
REMARK 465 PRO M 138
REMARK 465 LEU M 139
REMARK 465 ALA M 140
REMARK 465 PRO M 141
REMARK 465 SER M 142
REMARK 465 SER M 143
REMARK 465 LYS M 144
REMARK 465 SER M 145
REMARK 465 THR M 146
REMARK 465 SER M 147
REMARK 465 GLY M 148
REMARK 465 GLY M 149
REMARK 465 THR M 150
REMARK 465 ALA M 151
REMARK 465 ALA M 152
REMARK 465 LEU M 153
REMARK 465 GLY M 154
REMARK 465 CYS M 155
REMARK 465 LEU M 156
REMARK 465 VAL M 157
REMARK 465 LYS M 158
REMARK 465 ASP M 159
REMARK 465 TYR M 160
REMARK 465 PHE M 161
REMARK 465 PRO M 162
REMARK 465 GLU M 163
REMARK 465 PRO M 164
REMARK 465 VAL M 165
REMARK 465 THR M 166
REMARK 465 VAL M 167
REMARK 465 SER M 168
REMARK 465 TRP M 169
REMARK 465 ASN M 170
REMARK 465 SER M 171
REMARK 465 GLY M 172
REMARK 465 ALA M 173
REMARK 465 LEU M 174
REMARK 465 THR M 175
REMARK 465 SER M 176
REMARK 465 GLY M 177
REMARK 465 VAL M 178
REMARK 465 HIS M 179
REMARK 465 THR M 180
REMARK 465 PHE M 181
REMARK 465 PRO M 182
REMARK 465 ALA M 183
REMARK 465 VAL M 184
REMARK 465 LEU M 185
REMARK 465 GLN M 186
REMARK 465 SER M 187
REMARK 465 SER M 188
REMARK 465 GLY M 189
REMARK 465 LEU M 190
REMARK 465 TYR M 191
REMARK 465 SER M 192
REMARK 465 LEU M 193
REMARK 465 SER M 194
REMARK 465 SER M 195
REMARK 465 VAL M 196
REMARK 465 VAL M 197
REMARK 465 THR M 198
REMARK 465 VAL M 199
REMARK 465 PRO M 200
REMARK 465 SER M 201
REMARK 465 SER M 202
REMARK 465 SER M 203
REMARK 465 LEU M 204
REMARK 465 GLY M 205
REMARK 465 THR M 206
REMARK 465 GLN M 207
REMARK 465 THR M 208
REMARK 465 TYR M 209
REMARK 465 ILE M 210
REMARK 465 CYS M 211
REMARK 465 ASN M 212
REMARK 465 VAL M 213
REMARK 465 ASN M 214
REMARK 465 HIS M 215
REMARK 465 LYS M 216
REMARK 465 PRO M 217
REMARK 465 SER M 218
REMARK 465 ASN M 219
REMARK 465 THR M 220
REMARK 465 LYS M 221
REMARK 465 VAL M 222
REMARK 465 ASP M 223
REMARK 465 LYS M 224
REMARK 465 LYS M 225
REMARK 465 VAL M 226
REMARK 465 GLU M 227
REMARK 465 PRO M 228
REMARK 465 LYS M 229
REMARK 465 VAL N 3
REMARK 465 LYS N 109
REMARK 465 ARG N 110
REMARK 465 THR N 111
REMARK 465 VAL N 112
REMARK 465 ALA N 113
REMARK 465 ALA N 114
REMARK 465 PRO N 115
REMARK 465 SER N 116
REMARK 465 VAL N 117
REMARK 465 PHE N 118
REMARK 465 ILE N 119
REMARK 465 PHE N 120
REMARK 465 PRO N 121
REMARK 465 PRO N 122
REMARK 465 SER N 123
REMARK 465 ASP N 124
REMARK 465 GLU N 125
REMARK 465 GLN N 126
REMARK 465 LEU N 127
REMARK 465 LYS N 128
REMARK 465 SER N 129
REMARK 465 GLY N 130
REMARK 465 THR N 131
REMARK 465 ALA N 132
REMARK 465 SER N 133
REMARK 465 VAL N 134
REMARK 465 VAL N 135
REMARK 465 CYS N 136
REMARK 465 LEU N 137
REMARK 465 LEU N 138
REMARK 465 ASN N 139
REMARK 465 ASN N 140
REMARK 465 PHE N 141
REMARK 465 TYR N 142
REMARK 465 PRO N 143
REMARK 465 ARG N 144
REMARK 465 GLU N 145
REMARK 465 ALA N 146
REMARK 465 LYS N 147
REMARK 465 VAL N 148
REMARK 465 GLN N 149
REMARK 465 TRP N 150
REMARK 465 LYS N 151
REMARK 465 VAL N 152
REMARK 465 ASP N 153
REMARK 465 ASN N 154
REMARK 465 ALA N 155
REMARK 465 LEU N 156
REMARK 465 GLN N 157
REMARK 465 SER N 158
REMARK 465 GLY N 159
REMARK 465 ASN N 160
REMARK 465 SER N 161
REMARK 465 GLN N 162
REMARK 465 GLU N 163
REMARK 465 SER N 164
REMARK 465 VAL N 165
REMARK 465 THR N 166
REMARK 465 GLU N 167
REMARK 465 GLN N 168
REMARK 465 ASP N 169
REMARK 465 SER N 170
REMARK 465 LYS N 171
REMARK 465 ASP N 172
REMARK 465 SER N 173
REMARK 465 THR N 174
REMARK 465 TYR N 175
REMARK 465 SER N 176
REMARK 465 LEU N 177
REMARK 465 SER N 178
REMARK 465 SER N 179
REMARK 465 THR N 180
REMARK 465 LEU N 181
REMARK 465 THR N 182
REMARK 465 LEU N 183
REMARK 465 SER N 184
REMARK 465 LYS N 185
REMARK 465 ALA N 186
REMARK 465 ASP N 187
REMARK 465 TYR N 188
REMARK 465 GLU N 189
REMARK 465 LYS N 190
REMARK 465 HIS N 191
REMARK 465 LYS N 192
REMARK 465 VAL N 193
REMARK 465 TYR N 194
REMARK 465 ALA N 195
REMARK 465 CYS N 196
REMARK 465 GLU N 197
REMARK 465 VAL N 198
REMARK 465 THR N 199
REMARK 465 HIS N 200
REMARK 465 GLN N 201
REMARK 465 GLY N 202
REMARK 465 LEU N 203
REMARK 465 SER N 204
REMARK 465 SER N 205
REMARK 465 PRO N 206
REMARK 465 VAL N 207
REMARK 465 THR N 208
REMARK 465 LYS N 209
REMARK 465 SER N 210
REMARK 465 PHE N 211
REMARK 465 ASN N 212
REMARK 465 ARG N 213
REMARK 465 GLY N 214
REMARK 465 SER O 128
REMARK 465 ALA O 129
REMARK 465 SER O 130
REMARK 465 THR O 131
REMARK 465 LYS O 132
REMARK 465 GLY O 133
REMARK 465 PRO O 134
REMARK 465 SER O 135
REMARK 465 VAL O 136
REMARK 465 PHE O 137
REMARK 465 PRO O 138
REMARK 465 LEU O 139
REMARK 465 ALA O 140
REMARK 465 PRO O 141
REMARK 465 SER O 142
REMARK 465 SER O 143
REMARK 465 LYS O 144
REMARK 465 SER O 145
REMARK 465 THR O 146
REMARK 465 SER O 147
REMARK 465 GLY O 148
REMARK 465 GLY O 149
REMARK 465 THR O 150
REMARK 465 ALA O 151
REMARK 465 ALA O 152
REMARK 465 LEU O 153
REMARK 465 GLY O 154
REMARK 465 CYS O 155
REMARK 465 LEU O 156
REMARK 465 VAL O 157
REMARK 465 LYS O 158
REMARK 465 ASP O 159
REMARK 465 TYR O 160
REMARK 465 PHE O 161
REMARK 465 PRO O 162
REMARK 465 GLU O 163
REMARK 465 PRO O 164
REMARK 465 VAL O 165
REMARK 465 THR O 166
REMARK 465 VAL O 167
REMARK 465 SER O 168
REMARK 465 TRP O 169
REMARK 465 ASN O 170
REMARK 465 SER O 171
REMARK 465 GLY O 172
REMARK 465 ALA O 173
REMARK 465 LEU O 174
REMARK 465 THR O 175
REMARK 465 SER O 176
REMARK 465 GLY O 177
REMARK 465 VAL O 178
REMARK 465 HIS O 179
REMARK 465 THR O 180
REMARK 465 PHE O 181
REMARK 465 PRO O 182
REMARK 465 ALA O 183
REMARK 465 VAL O 184
REMARK 465 LEU O 185
REMARK 465 GLN O 186
REMARK 465 SER O 187
REMARK 465 SER O 188
REMARK 465 GLY O 189
REMARK 465 LEU O 190
REMARK 465 TYR O 191
REMARK 465 SER O 192
REMARK 465 LEU O 193
REMARK 465 SER O 194
REMARK 465 SER O 195
REMARK 465 VAL O 196
REMARK 465 VAL O 197
REMARK 465 THR O 198
REMARK 465 VAL O 199
REMARK 465 PRO O 200
REMARK 465 SER O 201
REMARK 465 SER O 202
REMARK 465 SER O 203
REMARK 465 LEU O 204
REMARK 465 GLY O 205
REMARK 465 THR O 206
REMARK 465 GLN O 207
REMARK 465 THR O 208
REMARK 465 TYR O 209
REMARK 465 ILE O 210
REMARK 465 CYS O 211
REMARK 465 ASN O 212
REMARK 465 VAL O 213
REMARK 465 ASN O 214
REMARK 465 HIS O 215
REMARK 465 LYS O 216
REMARK 465 PRO O 217
REMARK 465 SER O 218
REMARK 465 ASN O 219
REMARK 465 THR O 220
REMARK 465 LYS O 221
REMARK 465 VAL O 222
REMARK 465 ASP O 223
REMARK 465 LYS O 224
REMARK 465 LYS O 225
REMARK 465 VAL O 226
REMARK 465 GLU O 227
REMARK 465 PRO O 228
REMARK 465 LYS O 229
REMARK 465 ALA P 132
REMARK 465 ALA P 133
REMARK 465 SER P 134
REMARK 465 THR P 135
REMARK 465 LYS P 136
REMARK 465 GLY P 137
REMARK 465 PRO P 138
REMARK 465 SER P 139
REMARK 465 VAL P 140
REMARK 465 PHE P 141
REMARK 465 PRO P 142
REMARK 465 LEU P 143
REMARK 465 ALA P 144
REMARK 465 PRO P 145
REMARK 465 SER P 146
REMARK 465 SER P 147
REMARK 465 LYS P 148
REMARK 465 SER P 149
REMARK 465 THR P 150
REMARK 465 SER P 151
REMARK 465 GLY P 152
REMARK 465 GLY P 153
REMARK 465 THR P 154
REMARK 465 ALA P 155
REMARK 465 ALA P 156
REMARK 465 LEU P 157
REMARK 465 GLY P 158
REMARK 465 CYS P 159
REMARK 465 LEU P 160
REMARK 465 VAL P 161
REMARK 465 LYS P 162
REMARK 465 ASP P 163
REMARK 465 TYR P 164
REMARK 465 PHE P 165
REMARK 465 PRO P 166
REMARK 465 GLU P 167
REMARK 465 PRO P 168
REMARK 465 VAL P 169
REMARK 465 THR P 170
REMARK 465 VAL P 171
REMARK 465 SER P 172
REMARK 465 TRP P 173
REMARK 465 ASN P 174
REMARK 465 SER P 175
REMARK 465 GLY P 176
REMARK 465 ALA P 177
REMARK 465 LEU P 178
REMARK 465 THR P 179
REMARK 465 SER P 180
REMARK 465 GLY P 181
REMARK 465 VAL P 182
REMARK 465 HIS P 183
REMARK 465 THR P 184
REMARK 465 PHE P 185
REMARK 465 PRO P 186
REMARK 465 ALA P 187
REMARK 465 VAL P 188
REMARK 465 LEU P 189
REMARK 465 GLN P 190
REMARK 465 SER P 191
REMARK 465 SER P 192
REMARK 465 GLY P 193
REMARK 465 LEU P 194
REMARK 465 TYR P 195
REMARK 465 SER P 196
REMARK 465 LEU P 197
REMARK 465 SER P 198
REMARK 465 SER P 199
REMARK 465 VAL P 200
REMARK 465 VAL P 201
REMARK 465 THR P 202
REMARK 465 VAL P 203
REMARK 465 PRO P 204
REMARK 465 SER P 205
REMARK 465 SER P 206
REMARK 465 SER P 207
REMARK 465 LEU P 208
REMARK 465 GLY P 209
REMARK 465 THR P 210
REMARK 465 GLN P 211
REMARK 465 THR P 212
REMARK 465 TYR P 213
REMARK 465 ILE P 214
REMARK 465 CYS P 215
REMARK 465 ASN P 216
REMARK 465 VAL P 217
REMARK 465 ASN P 218
REMARK 465 HIS P 219
REMARK 465 LYS P 220
REMARK 465 PRO P 221
REMARK 465 SER P 222
REMARK 465 ASN P 223
REMARK 465 THR P 224
REMARK 465 LYS P 225
REMARK 465 VAL P 226
REMARK 465 ASP P 227
REMARK 465 LYS P 228
REMARK 465 ARG P 229
REMARK 465 VAL P 230
REMARK 465 GLU P 231
REMARK 465 PRO P 232
REMARK 465 LYS P 233
REMARK 465 SER P 234
REMARK 465 CYS P 235
REMARK 465 ASP P 236
REMARK 465 LYS P 237
REMARK 465 THR P 238
REMARK 465 HIS P 239
REMARK 465 HIS P 240
REMARK 465 HIS P 241
REMARK 465 HIS P 242
REMARK 465 HIS P 243
REMARK 465 HIS P 244
REMARK 465 LYS Q 108
REMARK 465 ARG Q 109
REMARK 465 THR Q 110
REMARK 465 VAL Q 111
REMARK 465 ALA Q 112
REMARK 465 ALA Q 113
REMARK 465 PRO Q 114
REMARK 465 SER Q 115
REMARK 465 VAL Q 116
REMARK 465 PHE Q 117
REMARK 465 ILE Q 118
REMARK 465 PHE Q 119
REMARK 465 PRO Q 120
REMARK 465 PRO Q 121
REMARK 465 SER Q 122
REMARK 465 ASP Q 123
REMARK 465 GLU Q 124
REMARK 465 GLN Q 125
REMARK 465 LEU Q 126
REMARK 465 LYS Q 127
REMARK 465 SER Q 128
REMARK 465 GLY Q 129
REMARK 465 THR Q 130
REMARK 465 ALA Q 131
REMARK 465 SER Q 132
REMARK 465 VAL Q 133
REMARK 465 VAL Q 134
REMARK 465 CYS Q 135
REMARK 465 LEU Q 136
REMARK 465 LEU Q 137
REMARK 465 ASN Q 138
REMARK 465 ASN Q 139
REMARK 465 PHE Q 140
REMARK 465 TYR Q 141
REMARK 465 PRO Q 142
REMARK 465 ARG Q 143
REMARK 465 GLU Q 144
REMARK 465 ALA Q 145
REMARK 465 LYS Q 146
REMARK 465 VAL Q 147
REMARK 465 GLN Q 148
REMARK 465 TRP Q 149
REMARK 465 LYS Q 150
REMARK 465 VAL Q 151
REMARK 465 ASP Q 152
REMARK 465 ASN Q 153
REMARK 465 ALA Q 154
REMARK 465 LEU Q 155
REMARK 465 GLN Q 156
REMARK 465 SER Q 157
REMARK 465 GLY Q 158
REMARK 465 ASN Q 159
REMARK 465 SER Q 160
REMARK 465 GLN Q 161
REMARK 465 GLU Q 162
REMARK 465 SER Q 163
REMARK 465 VAL Q 164
REMARK 465 THR Q 165
REMARK 465 GLU Q 166
REMARK 465 GLN Q 167
REMARK 465 ASP Q 168
REMARK 465 SER Q 169
REMARK 465 LYS Q 170
REMARK 465 ASP Q 171
REMARK 465 SER Q 172
REMARK 465 THR Q 173
REMARK 465 TYR Q 174
REMARK 465 SER Q 175
REMARK 465 LEU Q 176
REMARK 465 SER Q 177
REMARK 465 SER Q 178
REMARK 465 THR Q 179
REMARK 465 LEU Q 180
REMARK 465 THR Q 181
REMARK 465 LEU Q 182
REMARK 465 SER Q 183
REMARK 465 LYS Q 184
REMARK 465 ALA Q 185
REMARK 465 ASP Q 186
REMARK 465 TYR Q 187
REMARK 465 GLU Q 188
REMARK 465 LYS Q 189
REMARK 465 HIS Q 190
REMARK 465 LYS Q 191
REMARK 465 VAL Q 192
REMARK 465 TYR Q 193
REMARK 465 ALA Q 194
REMARK 465 CYS Q 195
REMARK 465 GLU Q 196
REMARK 465 VAL Q 197
REMARK 465 THR Q 198
REMARK 465 HIS Q 199
REMARK 465 GLN Q 200
REMARK 465 GLY Q 201
REMARK 465 LEU Q 202
REMARK 465 SER Q 203
REMARK 465 SER Q 204
REMARK 465 PRO Q 205
REMARK 465 VAL Q 206
REMARK 465 THR Q 207
REMARK 465 LYS Q 208
REMARK 465 SER Q 209
REMARK 465 PHE Q 210
REMARK 465 ASN Q 211
REMARK 465 ARG Q 212
REMARK 465 GLY Q 213
REMARK 465 GLU Q 214
REMARK 465 CYS Q 215
REMARK 465 ALA R 132
REMARK 465 ALA R 133
REMARK 465 SER R 134
REMARK 465 THR R 135
REMARK 465 LYS R 136
REMARK 465 GLY R 137
REMARK 465 PRO R 138
REMARK 465 SER R 139
REMARK 465 VAL R 140
REMARK 465 PHE R 141
REMARK 465 PRO R 142
REMARK 465 LEU R 143
REMARK 465 ALA R 144
REMARK 465 PRO R 145
REMARK 465 SER R 146
REMARK 465 SER R 147
REMARK 465 LYS R 148
REMARK 465 SER R 149
REMARK 465 THR R 150
REMARK 465 SER R 151
REMARK 465 GLY R 152
REMARK 465 GLY R 153
REMARK 465 THR R 154
REMARK 465 ALA R 155
REMARK 465 ALA R 156
REMARK 465 LEU R 157
REMARK 465 GLY R 158
REMARK 465 CYS R 159
REMARK 465 LEU R 160
REMARK 465 VAL R 161
REMARK 465 LYS R 162
REMARK 465 ASP R 163
REMARK 465 TYR R 164
REMARK 465 PHE R 165
REMARK 465 PRO R 166
REMARK 465 GLU R 167
REMARK 465 PRO R 168
REMARK 465 VAL R 169
REMARK 465 THR R 170
REMARK 465 VAL R 171
REMARK 465 SER R 172
REMARK 465 TRP R 173
REMARK 465 ASN R 174
REMARK 465 SER R 175
REMARK 465 GLY R 176
REMARK 465 ALA R 177
REMARK 465 LEU R 178
REMARK 465 THR R 179
REMARK 465 SER R 180
REMARK 465 GLY R 181
REMARK 465 VAL R 182
REMARK 465 HIS R 183
REMARK 465 THR R 184
REMARK 465 PHE R 185
REMARK 465 PRO R 186
REMARK 465 ALA R 187
REMARK 465 VAL R 188
REMARK 465 LEU R 189
REMARK 465 GLN R 190
REMARK 465 SER R 191
REMARK 465 SER R 192
REMARK 465 GLY R 193
REMARK 465 LEU R 194
REMARK 465 TYR R 195
REMARK 465 SER R 196
REMARK 465 LEU R 197
REMARK 465 SER R 198
REMARK 465 SER R 199
REMARK 465 VAL R 200
REMARK 465 VAL R 201
REMARK 465 THR R 202
REMARK 465 VAL R 203
REMARK 465 PRO R 204
REMARK 465 SER R 205
REMARK 465 SER R 206
REMARK 465 SER R 207
REMARK 465 LEU R 208
REMARK 465 GLY R 209
REMARK 465 THR R 210
REMARK 465 GLN R 211
REMARK 465 THR R 212
REMARK 465 TYR R 213
REMARK 465 ILE R 214
REMARK 465 CYS R 215
REMARK 465 ASN R 216
REMARK 465 VAL R 217
REMARK 465 ASN R 218
REMARK 465 HIS R 219
REMARK 465 LYS R 220
REMARK 465 PRO R 221
REMARK 465 SER R 222
REMARK 465 ASN R 223
REMARK 465 THR R 224
REMARK 465 LYS R 225
REMARK 465 VAL R 226
REMARK 465 ASP R 227
REMARK 465 LYS R 228
REMARK 465 ARG R 229
REMARK 465 VAL R 230
REMARK 465 GLU R 231
REMARK 465 PRO R 232
REMARK 465 LYS R 233
REMARK 465 SER R 234
REMARK 465 CYS R 235
REMARK 465 ASP R 236
REMARK 465 LYS R 237
REMARK 465 THR R 238
REMARK 465 HIS R 239
REMARK 465 HIS R 240
REMARK 465 HIS R 241
REMARK 465 HIS R 242
REMARK 465 HIS R 243
REMARK 465 HIS R 244
REMARK 465 LYS S 108
REMARK 465 ARG S 109
REMARK 465 THR S 110
REMARK 465 VAL S 111
REMARK 465 ALA S 112
REMARK 465 ALA S 113
REMARK 465 PRO S 114
REMARK 465 SER S 115
REMARK 465 VAL S 116
REMARK 465 PHE S 117
REMARK 465 ILE S 118
REMARK 465 PHE S 119
REMARK 465 PRO S 120
REMARK 465 PRO S 121
REMARK 465 SER S 122
REMARK 465 ASP S 123
REMARK 465 GLU S 124
REMARK 465 GLN S 125
REMARK 465 LEU S 126
REMARK 465 LYS S 127
REMARK 465 SER S 128
REMARK 465 GLY S 129
REMARK 465 THR S 130
REMARK 465 ALA S 131
REMARK 465 SER S 132
REMARK 465 VAL S 133
REMARK 465 VAL S 134
REMARK 465 CYS S 135
REMARK 465 LEU S 136
REMARK 465 LEU S 137
REMARK 465 ASN S 138
REMARK 465 ASN S 139
REMARK 465 PHE S 140
REMARK 465 TYR S 141
REMARK 465 PRO S 142
REMARK 465 ARG S 143
REMARK 465 GLU S 144
REMARK 465 ALA S 145
REMARK 465 LYS S 146
REMARK 465 VAL S 147
REMARK 465 GLN S 148
REMARK 465 TRP S 149
REMARK 465 LYS S 150
REMARK 465 VAL S 151
REMARK 465 ASP S 152
REMARK 465 ASN S 153
REMARK 465 ALA S 154
REMARK 465 LEU S 155
REMARK 465 GLN S 156
REMARK 465 SER S 157
REMARK 465 GLY S 158
REMARK 465 ASN S 159
REMARK 465 SER S 160
REMARK 465 GLN S 161
REMARK 465 GLU S 162
REMARK 465 SER S 163
REMARK 465 VAL S 164
REMARK 465 THR S 165
REMARK 465 GLU S 166
REMARK 465 GLN S 167
REMARK 465 ASP S 168
REMARK 465 SER S 169
REMARK 465 LYS S 170
REMARK 465 ASP S 171
REMARK 465 SER S 172
REMARK 465 THR S 173
REMARK 465 TYR S 174
REMARK 465 SER S 175
REMARK 465 LEU S 176
REMARK 465 SER S 177
REMARK 465 SER S 178
REMARK 465 THR S 179
REMARK 465 LEU S 180
REMARK 465 THR S 181
REMARK 465 LEU S 182
REMARK 465 SER S 183
REMARK 465 LYS S 184
REMARK 465 ALA S 185
REMARK 465 ASP S 186
REMARK 465 TYR S 187
REMARK 465 GLU S 188
REMARK 465 LYS S 189
REMARK 465 HIS S 190
REMARK 465 LYS S 191
REMARK 465 VAL S 192
REMARK 465 TYR S 193
REMARK 465 ALA S 194
REMARK 465 CYS S 195
REMARK 465 GLU S 196
REMARK 465 VAL S 197
REMARK 465 THR S 198
REMARK 465 HIS S 199
REMARK 465 GLN S 200
REMARK 465 GLY S 201
REMARK 465 LEU S 202
REMARK 465 SER S 203
REMARK 465 SER S 204
REMARK 465 PRO S 205
REMARK 465 VAL S 206
REMARK 465 THR S 207
REMARK 465 LYS S 208
REMARK 465 SER S 209
REMARK 465 PHE S 210
REMARK 465 ASN S 211
REMARK 465 ARG S 212
REMARK 465 GLY S 213
REMARK 465 GLU S 214
REMARK 465 CYS S 215
REMARK 465 ALA T 132
REMARK 465 ALA T 133
REMARK 465 SER T 134
REMARK 465 THR T 135
REMARK 465 LYS T 136
REMARK 465 GLY T 137
REMARK 465 PRO T 138
REMARK 465 SER T 139
REMARK 465 VAL T 140
REMARK 465 PHE T 141
REMARK 465 PRO T 142
REMARK 465 LEU T 143
REMARK 465 ALA T 144
REMARK 465 PRO T 145
REMARK 465 SER T 146
REMARK 465 SER T 147
REMARK 465 LYS T 148
REMARK 465 SER T 149
REMARK 465 THR T 150
REMARK 465 SER T 151
REMARK 465 GLY T 152
REMARK 465 GLY T 153
REMARK 465 THR T 154
REMARK 465 ALA T 155
REMARK 465 ALA T 156
REMARK 465 LEU T 157
REMARK 465 GLY T 158
REMARK 465 CYS T 159
REMARK 465 LEU T 160
REMARK 465 VAL T 161
REMARK 465 LYS T 162
REMARK 465 ASP T 163
REMARK 465 TYR T 164
REMARK 465 PHE T 165
REMARK 465 PRO T 166
REMARK 465 GLU T 167
REMARK 465 PRO T 168
REMARK 465 VAL T 169
REMARK 465 THR T 170
REMARK 465 VAL T 171
REMARK 465 SER T 172
REMARK 465 TRP T 173
REMARK 465 ASN T 174
REMARK 465 SER T 175
REMARK 465 GLY T 176
REMARK 465 ALA T 177
REMARK 465 LEU T 178
REMARK 465 THR T 179
REMARK 465 SER T 180
REMARK 465 GLY T 181
REMARK 465 VAL T 182
REMARK 465 HIS T 183
REMARK 465 THR T 184
REMARK 465 PHE T 185
REMARK 465 PRO T 186
REMARK 465 ALA T 187
REMARK 465 VAL T 188
REMARK 465 LEU T 189
REMARK 465 GLN T 190
REMARK 465 SER T 191
REMARK 465 SER T 192
REMARK 465 GLY T 193
REMARK 465 LEU T 194
REMARK 465 TYR T 195
REMARK 465 SER T 196
REMARK 465 LEU T 197
REMARK 465 SER T 198
REMARK 465 SER T 199
REMARK 465 VAL T 200
REMARK 465 VAL T 201
REMARK 465 THR T 202
REMARK 465 VAL T 203
REMARK 465 PRO T 204
REMARK 465 SER T 205
REMARK 465 SER T 206
REMARK 465 SER T 207
REMARK 465 LEU T 208
REMARK 465 GLY T 209
REMARK 465 THR T 210
REMARK 465 GLN T 211
REMARK 465 THR T 212
REMARK 465 TYR T 213
REMARK 465 ILE T 214
REMARK 465 CYS T 215
REMARK 465 ASN T 216
REMARK 465 VAL T 217
REMARK 465 ASN T 218
REMARK 465 HIS T 219
REMARK 465 LYS T 220
REMARK 465 PRO T 221
REMARK 465 SER T 222
REMARK 465 ASN T 223
REMARK 465 THR T 224
REMARK 465 LYS T 225
REMARK 465 VAL T 226
REMARK 465 ASP T 227
REMARK 465 LYS T 228
REMARK 465 ARG T 229
REMARK 465 VAL T 230
REMARK 465 GLU T 231
REMARK 465 PRO T 232
REMARK 465 LYS T 233
REMARK 465 SER T 234
REMARK 465 CYS T 235
REMARK 465 ASP T 236
REMARK 465 LYS T 237
REMARK 465 THR T 238
REMARK 465 HIS T 239
REMARK 465 HIS T 240
REMARK 465 HIS T 241
REMARK 465 HIS T 242
REMARK 465 HIS T 243
REMARK 465 HIS T 244
REMARK 465 LYS U 108
REMARK 465 ARG U 109
REMARK 465 THR U 110
REMARK 465 VAL U 111
REMARK 465 ALA U 112
REMARK 465 ALA U 113
REMARK 465 PRO U 114
REMARK 465 SER U 115
REMARK 465 VAL U 116
REMARK 465 PHE U 117
REMARK 465 ILE U 118
REMARK 465 PHE U 119
REMARK 465 PRO U 120
REMARK 465 PRO U 121
REMARK 465 SER U 122
REMARK 465 ASP U 123
REMARK 465 GLU U 124
REMARK 465 GLN U 125
REMARK 465 LEU U 126
REMARK 465 LYS U 127
REMARK 465 SER U 128
REMARK 465 GLY U 129
REMARK 465 THR U 130
REMARK 465 ALA U 131
REMARK 465 SER U 132
REMARK 465 VAL U 133
REMARK 465 VAL U 134
REMARK 465 CYS U 135
REMARK 465 LEU U 136
REMARK 465 LEU U 137
REMARK 465 ASN U 138
REMARK 465 ASN U 139
REMARK 465 PHE U 140
REMARK 465 TYR U 141
REMARK 465 PRO U 142
REMARK 465 ARG U 143
REMARK 465 GLU U 144
REMARK 465 ALA U 145
REMARK 465 LYS U 146
REMARK 465 VAL U 147
REMARK 465 GLN U 148
REMARK 465 TRP U 149
REMARK 465 LYS U 150
REMARK 465 VAL U 151
REMARK 465 ASP U 152
REMARK 465 ASN U 153
REMARK 465 ALA U 154
REMARK 465 LEU U 155
REMARK 465 GLN U 156
REMARK 465 SER U 157
REMARK 465 GLY U 158
REMARK 465 ASN U 159
REMARK 465 SER U 160
REMARK 465 GLN U 161
REMARK 465 GLU U 162
REMARK 465 SER U 163
REMARK 465 VAL U 164
REMARK 465 THR U 165
REMARK 465 GLU U 166
REMARK 465 GLN U 167
REMARK 465 ASP U 168
REMARK 465 SER U 169
REMARK 465 LYS U 170
REMARK 465 ASP U 171
REMARK 465 SER U 172
REMARK 465 THR U 173
REMARK 465 TYR U 174
REMARK 465 SER U 175
REMARK 465 LEU U 176
REMARK 465 SER U 177
REMARK 465 SER U 178
REMARK 465 THR U 179
REMARK 465 LEU U 180
REMARK 465 THR U 181
REMARK 465 LEU U 182
REMARK 465 SER U 183
REMARK 465 LYS U 184
REMARK 465 ALA U 185
REMARK 465 ASP U 186
REMARK 465 TYR U 187
REMARK 465 GLU U 188
REMARK 465 LYS U 189
REMARK 465 HIS U 190
REMARK 465 LYS U 191
REMARK 465 VAL U 192
REMARK 465 TYR U 193
REMARK 465 ALA U 194
REMARK 465 CYS U 195
REMARK 465 GLU U 196
REMARK 465 VAL U 197
REMARK 465 THR U 198
REMARK 465 HIS U 199
REMARK 465 GLN U 200
REMARK 465 GLY U 201
REMARK 465 LEU U 202
REMARK 465 SER U 203
REMARK 465 SER U 204
REMARK 465 PRO U 205
REMARK 465 VAL U 206
REMARK 465 THR U 207
REMARK 465 LYS U 208
REMARK 465 SER U 209
REMARK 465 PHE U 210
REMARK 465 ASN U 211
REMARK 465 ARG U 212
REMARK 465 GLY U 213
REMARK 465 GLU U 214
REMARK 465 CYS U 215
REMARK 470
REMARK 470 MISSING ATOM
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;
REMARK 470 I=INSERTION CODE):
REMARK 470 M RES CSSEQI ATOMS
REMARK 470 VAL A 518 CG1 CG2
REMARK 470 MET A 535 CG SD CE
REMARK 470 GLN A 540 CG CD OE1 NE2
REMARK 470 ARG A 542 CG CD NE CZ NH1 NH2
REMARK 470 LEU A 544 CG CD1 CD2
REMARK 470 HIS A 564 CG ND1 CD2 CE1 NE2
REMARK 470 LYS A 567 CG CD CE NZ
REMARK 470 GLU A 621 CG CD OE1 OE2
REMARK 470 GLU A 648 CG CD OE1 OE2
REMARK 470 GLN A 650 CG CD OE1 NE2
REMARK 470 VAL B 518 CG1 CG2
REMARK 470 MET B 535 CG SD CE
REMARK 470 GLN B 540 CG CD OE1 NE2
REMARK 470 ARG B 542 CG CD NE CZ NH1 NH2
REMARK 470 LEU B 544 CG CD1 CD2
REMARK 470 HIS B 564 CG ND1 CD2 CE1 NE2
REMARK 470 LYS B 567 CG CD CE NZ
REMARK 470 GLU B 621 CG CD OE1 OE2
REMARK 470 GLU B 648 CG CD OE1 OE2
REMARK 470 GLN B 650 CG CD OE1 NE2
REMARK 470 VAL C 518 CG1 CG2
REMARK 470 MET C 535 CG SD CE
REMARK 470 GLN C 540 CG CD OE1 NE2
REMARK 470 ARG C 542 CG CD NE CZ NH1 NH2
REMARK 470 LEU C 544 CG CD1 CD2
REMARK 470 HIS C 564 CG ND1 CD2 CE1 NE2
REMARK 470 LYS C 567 CG CD CE NZ
REMARK 470 GLU C 621 CG CD OE1 OE2
REMARK 470 GLU C 648 CG CD OE1 OE2
REMARK 470 GLN C 650 CG CD OE1 NE2
REMARK 470 GLU D 49 CG CD OE1 OE2
REMARK 470 LYS D 59 CG CD CE NZ
REMARK 470 HIS D 72 CG ND1 CD2 CE1 NE2
REMARK 470 GLU D 87 CG CD OE1 OE2
REMARK 470 LYS D 97 CG CD CE NZ
REMARK 470 LYS D 117 CG CD CE NZ
REMARK 470 GLN D 203 CG CD OE1 NE2
REMARK 470 LYS D 207 CG CD CE NZ
REMARK 470 VAL D 208 CG1 CG2
REMARK 470 GLU D 211 CG CD OE1 OE2
REMARK 470 LYS D 231 CG CD CE NZ
REMARK 470 LYS D 232 CG CD CE NZ
REMARK 470 GLU D 267 CG CD OE1 OE2
REMARK 470 GLU D 268 CG CD OE1 OE2
REMARK 470 GLU D 269 CG CD OE1 OE2
REMARK 470 GLU D 275 CG CD OE1 OE2
REMARK 470 ILE D 359 CG1 CG2 CD1
REMARK 470 ARG D 360 CG CD NE CZ NH1 NH2
REMARK 470 GLU D 370 CG CD OE1 OE2
REMARK 470 GLU D 381 CG CD OE1 OE2
REMARK 470 ILE D 396 CG1 CG2 CD1
REMARK 470 ARG D 419 CG CD NE CZ NH1 NH2
REMARK 470 ASP D 474 CG OD1 OD2
REMARK 470 ARG D 500 CG CD NE CZ NH1 NH2
REMARK 470 GLU E 49 CG CD OE1 OE2
REMARK 470 LYS E 59 CG CD CE NZ
REMARK 470 HIS E 72 CG ND1 CD2 CE1 NE2
REMARK 470 GLU E 87 CG CD OE1 OE2
REMARK 470 LYS E 97 CG CD CE NZ
REMARK 470 LYS E 117 CG CD CE NZ
REMARK 470 GLN E 203 CG CD OE1 NE2
REMARK 470 LYS E 207 CG CD CE NZ
REMARK 470 VAL E 208 CG1 CG2
REMARK 470 GLU E 211 CG CD OE1 OE2
REMARK 470 LYS E 231 CG CD CE NZ
REMARK 470 LYS E 232 CG CD CE NZ
REMARK 470 GLU E 267 CG CD OE1 OE2
REMARK 470 GLU E 268 CG CD OE1 OE2
REMARK 470 GLU E 269 CG CD OE1 OE2
REMARK 470 GLU E 275 CG CD OE1 OE2
REMARK 470 ILE E 359 CG1 CG2 CD1
REMARK 470 ARG E 360 CG CD NE CZ NH1 NH2
REMARK 470 GLU E 370 CG CD OE1 OE2
REMARK 470 GLU E 381 CG CD OE1 OE2
REMARK 470 ILE E 396 CG1 CG2 CD1
REMARK 470 ARG E 419 CG CD NE CZ NH1 NH2
REMARK 470 ASP E 474 CG OD1 OD2
REMARK 470 ARG E 500 CG CD NE CZ NH1 NH2
REMARK 470 GLU F 49 CG CD OE1 OE2
REMARK 470 LYS F 59 CG CD CE NZ
REMARK 470 HIS F 72 CG ND1 CD2 CE1 NE2
REMARK 470 GLU F 87 CG CD OE1 OE2
REMARK 470 LYS F 97 CG CD CE NZ
REMARK 470 LYS F 117 CG CD CE NZ
REMARK 470 GLN F 203 CG CD OE1 NE2
REMARK 470 LYS F 207 CG CD CE NZ
REMARK 470 VAL F 208 CG1 CG2
REMARK 470 GLU F 211 CG CD OE1 OE2
REMARK 470 LYS F 231 CG CD CE NZ
REMARK 470 LYS F 232 CG CD CE NZ
REMARK 470 GLU F 267 CG CD OE1 OE2
REMARK 470 GLU F 268 CG CD OE1 OE2
REMARK 470 GLU F 269 CG CD OE1 OE2
REMARK 470 GLU F 275 CG CD OE1 OE2
REMARK 470 ILE F 359 CG1 CG2 CD1
REMARK 470 ARG F 360 CG CD NE CZ NH1 NH2
REMARK 470 GLU F 370 CG CD OE1 OE2
REMARK 470 GLU F 381 CG CD OE1 OE2
REMARK 470 ILE F 396 CG1 CG2 CD1
REMARK 470 ARG F 419 CG CD NE CZ NH1 NH2
REMARK 470 ASP F 474 CG OD1 OD2
REMARK 470 ARG F 500 CG CD NE CZ NH1 NH2
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT
REMARK 500
REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT.
REMARK 500
REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI DISTANCE
REMARK 500 OE1 GLN E 440 O4 MAN d 5 1.80
REMARK 500 OE1 GLN F 440 O4 MAN h 5 1.80
REMARK 500 OE1 GLN D 440 O4 MAN Z 5 1.80
REMARK 500 OG SER L 22 OE2 GLU L 70 2.04
REMARK 500 OG SER N 22 OE2 GLU N 70 2.04
REMARK 500 OG SER J 22 OE2 GLU J 70 2.05
REMARK 500 OD2 ASP A 632 NE1 TRP R 108 2.12
REMARK 500 OD2 ASP B 632 NE1 TRP P 108 2.17
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: TORSION ANGLES
REMARK 500
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)
REMARK 500
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400
REMARK 500
REMARK 500 M RES CSSEQI PSI PHI
REMARK 500 ALA D 55 -156.70 -153.80
REMARK 500 ALA D 73 10.79 -141.99
REMARK 500 GLU D 87 -159.01 -80.14
REMARK 500 ASN D 88 65.99 -69.97
REMARK 500 SER D 115 -62.36 -93.64
REMARK 500 LEU D 193 46.78 -102.95
REMARK 500 PHE D 210 111.88 -160.02
REMARK 500 GLN D 258 -7.88 66.87
REMARK 500 THR D 278 -0.87 82.10
REMARK 500 ASN D 280 19.56 59.18
REMARK 500 ALA D 281 11.19 -142.43
REMARK 500 ASP D 325 70.46 56.99
REMARK 500 ARG D 327 33.30 -96.26
REMARK 500 ALA D 336 -4.09 67.95
REMARK 500 PRO D 438 -177.88 -67.04
REMARK 500 THR D 455 -169.54 -127.77
REMARK 500 THR D 464 -166.04 -125.59
REMARK 500 ALA E 55 -156.76 -153.76
REMARK 500 ALA E 73 10.83 -142.00
REMARK 500 GLU E 87 -159.00 -80.15
REMARK 500 SER E 115 -62.30 -93.65
REMARK 500 LEU E 193 46.75 -102.95
REMARK 500 PHE E 210 111.80 -160.04
REMARK 500 GLN E 258 -7.87 66.88
REMARK 500 THR E 278 -0.90 82.13
REMARK 500 ASN E 280 19.53 59.23
REMARK 500 ALA E 281 11.14 -142.40
REMARK 500 ASP E 325 70.39 57.05
REMARK 500 ARG E 327 33.34 -96.30
REMARK 500 ALA E 336 -4.11 67.97
REMARK 500 PRO E 438 -177.85 -67.06
REMARK 500 THR E 455 -169.57 -127.79
REMARK 500 THR E 464 -166.03 -125.60
REMARK 500 ALA F 55 -156.74 -153.81
REMARK 500 ALA F 73 10.85 -142.00
REMARK 500 GLU F 87 -158.96 -80.16
REMARK 500 ASN F 88 66.06 -69.99
REMARK 500 SER F 115 -62.38 -93.56
REMARK 500 LEU F 193 46.77 -102.93
REMARK 500 PHE F 210 111.82 -160.06
REMARK 500 GLN F 258 -7.78 66.77
REMARK 500 THR F 278 -0.86 82.11
REMARK 500 ASN F 280 19.52 59.26
REMARK 500 ALA F 281 11.14 -142.42
REMARK 500 ASP F 325 70.42 56.92
REMARK 500 ARG F 327 33.34 -96.27
REMARK 500 ALA F 336 -4.05 67.95
REMARK 500 PRO F 438 -177.88 -67.10
REMARK 500 THR F 455 -169.56 -127.76
REMARK 500 THR F 464 -166.03 -125.52
REMARK 500
REMARK 500 THIS ENTRY HAS 98 RAMACHANDRAN OUTLIERS.
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: NON-CIS, NON-TRANS
REMARK 500
REMARK 500 THE FOLLOWING PEPTIDE BONDS DEVIATE SIGNIFICANTLY FROM BOTH
REMARK 500 CIS AND TRANS CONFORMATION. CIS BONDS, IF ANY, ARE LISTED
REMARK 500 ON CISPEP RECORDS. TRANS IS DEFINED AS 180 +/- 30 AND
REMARK 500 CIS IS DEFINED AS 0 +/- 30 DEGREES.
REMARK 500 MODEL OMEGA
REMARK 500 TRP A 610 ASN A 611 149.97
REMARK 500 TRP B 610 ASN B 611 149.96
REMARK 500 TRP C 610 ASN C 611 149.99
REMARK 500
REMARK 500 REMARK: NULL
REMARK 900
REMARK 900 RELATED ENTRIES
REMARK 900 RELATED ID: EMD-8407 RELATED DB: EMDB
REMARK 900 RELATED ID: EMD-7516 RELATED DB: EMDB
REMARK 900 BG505 SOSIP IN COMPLEX WITH SCD4, 17B, 8ANC195
DBREF 6CM3 A 512 664 UNP Q2N0S7 Q2N0S7_9HIV1 509 661
DBREF 6CM3 B 512 664 UNP Q2N0S7 Q2N0S7_9HIV1 509 661
DBREF 6CM3 C 512 664 UNP Q2N0S7 Q2N0S7_9HIV1 509 661
DBREF 6CM3 D 31 511 UNP Q2N0S5 Q2N0S5_9HIV1 30 508
DBREF 6CM3 E 31 511 UNP Q2N0S5 Q2N0S5_9HIV1 30 508
DBREF 6CM3 F 31 511 UNP Q2N0S5 Q2N0S5_9HIV1 30 508
DBREF 6CM3 G 1 182 UNP P01730 CD4_HUMAN 26 207
DBREF 6CM3 H 1 182 UNP P01730 CD4_HUMAN 26 207
DBREF 6CM3 I 1 182 UNP P01730 CD4_HUMAN 26 207
DBREF 6CM3 J 1 214 PDB 6CM3 6CM3 1 214
DBREF 6CM3 K 1 229 PDB 6CM3 6CM3 1 229
DBREF 6CM3 L 1 214 PDB 6CM3 6CM3 1 214
DBREF 6CM3 M 1 229 PDB 6CM3 6CM3 1 229
DBREF 6CM3 N 1 214 PDB 6CM3 6CM3 1 214
DBREF 6CM3 O 1 229 PDB 6CM3 6CM3 1 229
DBREF 6CM3 P 1 244 PDB 6CM3 6CM3 1 244
DBREF 6CM3 Q 1 215 PDB 6CM3 6CM3 1 215
DBREF 6CM3 R 1 244 PDB 6CM3 6CM3 1 244
DBREF 6CM3 S 1 215 PDB 6CM3 6CM3 1 215
DBREF 6CM3 T 1 244 PDB 6CM3 6CM3 1 244
DBREF 6CM3 U 1 215 PDB 6CM3 6CM3 1 215
SEQADV 6CM3 PRO A 559 UNP Q2N0S7 ILE 556 CONFLICT
SEQADV 6CM3 CYS A 605 UNP Q2N0S7 THR 602 CONFLICT
SEQADV 6CM3 PRO B 559 UNP Q2N0S7 ILE 556 CONFLICT
SEQADV 6CM3 CYS B 605 UNP Q2N0S7 THR 602 CONFLICT
SEQADV 6CM3 PRO C 559 UNP Q2N0S7 ILE 556 CONFLICT
SEQADV 6CM3 CYS C 605 UNP Q2N0S7 THR 602 CONFLICT
SEQADV 6CM3 ASN D 332 UNP Q2N0S5 THR 330 CONFLICT
SEQADV 6CM3 CYS D 501 UNP Q2N0S5 ALA 498 CONFLICT
SEQADV 6CM3 ARG D 509 UNP Q2N0S5 GLU 506 CONFLICT
SEQADV 6CM3 ARG D 510 UNP Q2N0S5 LYS 507 CONFLICT
SEQADV 6CM3 ARG D 512 UNP Q2N0S5 EXPRESSION TAG
SEQADV 6CM3 ARG D 513 UNP Q2N0S5 EXPRESSION TAG
SEQADV 6CM3 ASN E 332 UNP Q2N0S5 THR 330 CONFLICT
SEQADV 6CM3 CYS E 501 UNP Q2N0S5 ALA 498 CONFLICT
SEQADV 6CM3 ARG E 509 UNP Q2N0S5 GLU 506 CONFLICT
SEQADV 6CM3 ARG E 510 UNP Q2N0S5 LYS 507 CONFLICT
SEQADV 6CM3 ARG E 512 UNP Q2N0S5 EXPRESSION TAG
SEQADV 6CM3 ARG E 513 UNP Q2N0S5 EXPRESSION TAG
SEQADV 6CM3 ASN F 332 UNP Q2N0S5 THR 330 CONFLICT
SEQADV 6CM3 CYS F 501 UNP Q2N0S5 ALA 498 CONFLICT
SEQADV 6CM3 ARG F 509 UNP Q2N0S5 GLU 506 CONFLICT
SEQADV 6CM3 ARG F 510 UNP Q2N0S5 LYS 507 CONFLICT
SEQADV 6CM3 ARG F 512 UNP Q2N0S5 EXPRESSION TAG
SEQADV 6CM3 ARG F 513 UNP Q2N0S5 EXPRESSION TAG
SEQADV 6CM3 ILE G 183 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 ASP G 184 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 GLY G 185 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 ARG G 186 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 HIS G 187 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 HIS G 188 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 HIS G 189 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 HIS G 190 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 HIS G 191 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 HIS G 192 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 ILE H 183 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 ASP H 184 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 GLY H 185 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 ARG H 186 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 HIS H 187 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 HIS H 188 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 HIS H 189 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 HIS H 190 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 HIS H 191 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 HIS H 192 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 ILE I 183 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 ASP I 184 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 GLY I 185 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 ARG I 186 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 HIS I 187 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 HIS I 188 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 HIS I 189 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 HIS I 190 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 HIS I 191 UNP P01730 EXPRESSION TAG
SEQADV 6CM3 HIS I 192 UNP P01730 EXPRESSION TAG
SEQRES 1 A 153 ALA VAL GLY ILE GLY ALA VAL PHE LEU GLY PHE LEU GLY
SEQRES 2 A 153 ALA ALA GLY SER THR MET GLY ALA ALA SER MET THR LEU
SEQRES 3 A 153 THR VAL GLN ALA ARG ASN LEU LEU SER GLY ILE VAL GLN
SEQRES 4 A 153 GLN GLN SER ASN LEU LEU ARG ALA PRO GLU ALA GLN GLN
SEQRES 5 A 153 HIS LEU LEU LYS LEU THR VAL TRP GLY ILE LYS GLN LEU
SEQRES 6 A 153 GLN ALA ARG VAL LEU ALA VAL GLU ARG TYR LEU ARG ASP
SEQRES 7 A 153 GLN GLN LEU LEU GLY ILE TRP GLY CYS SER GLY LYS LEU
SEQRES 8 A 153 ILE CYS CYS THR ASN VAL PRO TRP ASN SER SER TRP SER
SEQRES 9 A 153 ASN ARG ASN LEU SER GLU ILE TRP ASP ASN MET THR TRP
SEQRES 10 A 153 LEU GLN TRP ASP LYS GLU ILE SER ASN TYR THR GLN ILE
SEQRES 11 A 153 ILE TYR GLY LEU LEU GLU GLU SER GLN ASN GLN GLN GLU
SEQRES 12 A 153 LYS ASN GLU GLN ASP LEU LEU ALA LEU ASP
SEQRES 1 B 153 ALA VAL GLY ILE GLY ALA VAL PHE LEU GLY PHE LEU GLY
SEQRES 2 B 153 ALA ALA GLY SER THR MET GLY ALA ALA SER MET THR LEU
SEQRES 3 B 153 THR VAL GLN ALA ARG ASN LEU LEU SER GLY ILE VAL GLN
SEQRES 4 B 153 GLN GLN SER ASN LEU LEU ARG ALA PRO GLU ALA GLN GLN
SEQRES 5 B 153 HIS LEU LEU LYS LEU THR VAL TRP GLY ILE LYS GLN LEU
SEQRES 6 B 153 GLN ALA ARG VAL LEU ALA VAL GLU ARG TYR LEU ARG ASP
SEQRES 7 B 153 GLN GLN LEU LEU GLY ILE TRP GLY CYS SER GLY LYS LEU
SEQRES 8 B 153 ILE CYS CYS THR ASN VAL PRO TRP ASN SER SER TRP SER
SEQRES 9 B 153 ASN ARG ASN LEU SER GLU ILE TRP ASP ASN MET THR TRP
SEQRES 10 B 153 LEU GLN TRP ASP LYS GLU ILE SER ASN TYR THR GLN ILE
SEQRES 11 B 153 ILE TYR GLY LEU LEU GLU GLU SER GLN ASN GLN GLN GLU
SEQRES 12 B 153 LYS ASN GLU GLN ASP LEU LEU ALA LEU ASP
SEQRES 1 C 153 ALA VAL GLY ILE GLY ALA VAL PHE LEU GLY PHE LEU GLY
SEQRES 2 C 153 ALA ALA GLY SER THR MET GLY ALA ALA SER MET THR LEU
SEQRES 3 C 153 THR VAL GLN ALA ARG ASN LEU LEU SER GLY ILE VAL GLN
SEQRES 4 C 153 GLN GLN SER ASN LEU LEU ARG ALA PRO GLU ALA GLN GLN
SEQRES 5 C 153 HIS LEU LEU LYS LEU THR VAL TRP GLY ILE LYS GLN LEU
SEQRES 6 C 153 GLN ALA ARG VAL LEU ALA VAL GLU ARG TYR LEU ARG ASP
SEQRES 7 C 153 GLN GLN LEU LEU GLY ILE TRP GLY CYS SER GLY LYS LEU
SEQRES 8 C 153 ILE CYS CYS THR ASN VAL PRO TRP ASN SER SER TRP SER
SEQRES 9 C 153 ASN ARG ASN LEU SER GLU ILE TRP ASP ASN MET THR TRP
SEQRES 10 C 153 LEU GLN TRP ASP LYS GLU ILE SER ASN TYR THR GLN ILE
SEQRES 11 C 153 ILE TYR GLY LEU LEU GLU GLU SER GLN ASN GLN GLN GLU
SEQRES 12 C 153 LYS ASN GLU GLN ASP LEU LEU ALA LEU ASP
SEQRES 1 D 481 ALA GLU ASN LEU TRP VAL THR VAL TYR TYR GLY VAL PRO
SEQRES 2 D 481 VAL TRP LYS ASP ALA GLU THR THR LEU PHE CYS ALA SER
SEQRES 3 D 481 ASP ALA LYS ALA TYR GLU THR GLU LYS HIS ASN VAL TRP
SEQRES 4 D 481 ALA THR HIS ALA CYS VAL PRO THR ASP PRO ASN PRO GLN
SEQRES 5 D 481 GLU ILE HIS LEU GLU ASN VAL THR GLU GLU PHE ASN MET
SEQRES 6 D 481 TRP LYS ASN ASN MET VAL GLU GLN MET HIS THR ASP ILE
SEQRES 7 D 481 ILE SER LEU TRP ASP GLN SER LEU LYS PRO CYS VAL LYS
SEQRES 8 D 481 LEU THR PRO LEU CYS VAL THR LEU GLN CYS THR ASN VAL
SEQRES 9 D 481 THR ASN ASN ILE THR ASP ASP MET ARG GLY GLU LEU LYS
SEQRES 10 D 481 ASN CYS SER PHE ASN MET THR THR GLU LEU ARG ASP LYS
SEQRES 11 D 481 LYS GLN LYS VAL TYR SER LEU PHE TYR ARG LEU ASP VAL
SEQRES 12 D 481 VAL GLN ILE ASN GLU ASN GLN GLY ASN ARG SER ASN ASN
SEQRES 13 D 481 SER ASN LYS GLU TYR ARG LEU ILE ASN CYS ASN THR SER
SEQRES 14 D 481 ALA ILE THR GLN ALA CYS PRO LYS VAL SER PHE GLU PRO
SEQRES 15 D 481 ILE PRO ILE HIS TYR CYS ALA PRO ALA GLY PHE ALA ILE
SEQRES 16 D 481 LEU LYS CYS LYS ASP LYS LYS PHE ASN GLY THR GLY PRO
SEQRES 17 D 481 CYS PRO SER VAL SER THR VAL GLN CYS THR HIS GLY ILE
SEQRES 18 D 481 LYS PRO VAL VAL SER THR GLN LEU LEU LEU ASN GLY SER
SEQRES 19 D 481 LEU ALA GLU GLU GLU VAL MET ILE ARG SER GLU ASN ILE
SEQRES 20 D 481 THR ASN ASN ALA LYS ASN ILE LEU VAL GLN PHE ASN THR
SEQRES 21 D 481 PRO VAL GLN ILE ASN CYS THR ARG PRO ASN ASN ASN THR
SEQRES 22 D 481 ARG LYS SER ILE ARG ILE GLY PRO GLY GLN ALA PHE TYR
SEQRES 23 D 481 ALA THR GLY ASP ILE ILE GLY ASP ILE ARG GLN ALA HIS
SEQRES 24 D 481 CYS ASN VAL SER LYS ALA THR TRP ASN GLU THR LEU GLY
SEQRES 25 D 481 LYS VAL VAL LYS GLN LEU ARG LYS HIS PHE GLY ASN ASN
SEQRES 26 D 481 THR ILE ILE ARG PHE ALA ASN SER SER GLY GLY ASP LEU
SEQRES 27 D 481 GLU VAL THR THR HIS SER PHE ASN CYS GLY GLY GLU PHE
SEQRES 28 D 481 PHE TYR CYS ASN THR SER GLY LEU PHE ASN SER THR TRP
SEQRES 29 D 481 ILE SER ASN THR SER VAL GLN GLY SER ASN SER THR GLY
SEQRES 30 D 481 SER ASN ASP SER ILE THR LEU PRO CYS ARG ILE LYS GLN
SEQRES 31 D 481 ILE ILE ASN MET TRP GLN ARG ILE GLY GLN ALA MET TYR
SEQRES 32 D 481 ALA PRO PRO ILE GLN GLY VAL ILE ARG CYS VAL SER ASN
SEQRES 33 D 481 ILE THR GLY LEU ILE LEU THR ARG ASP GLY GLY SER THR
SEQRES 34 D 481 ASN SER THR THR GLU THR PHE ARG PRO GLY GLY GLY ASP
SEQRES 35 D 481 MET ARG ASP ASN TRP ARG SER GLU LEU TYR LYS TYR LYS
SEQRES 36 D 481 VAL VAL LYS ILE GLU PRO LEU GLY VAL ALA PRO THR ARG
SEQRES 37 D 481 CYS LYS ARG ARG VAL VAL GLY ARG ARG ARG ARG ARG ARG
SEQRES 1 E 481 ALA GLU ASN LEU TRP VAL THR VAL TYR TYR GLY VAL PRO
SEQRES 2 E 481 VAL TRP LYS ASP ALA GLU THR THR LEU PHE CYS ALA SER
SEQRES 3 E 481 ASP ALA LYS ALA TYR GLU THR GLU LYS HIS ASN VAL TRP
SEQRES 4 E 481 ALA THR HIS ALA CYS VAL PRO THR ASP PRO ASN PRO GLN
SEQRES 5 E 481 GLU ILE HIS LEU GLU ASN VAL THR GLU GLU PHE ASN MET
SEQRES 6 E 481 TRP LYS ASN ASN MET VAL GLU GLN MET HIS THR ASP ILE
SEQRES 7 E 481 ILE SER LEU TRP ASP GLN SER LEU LYS PRO CYS VAL LYS
SEQRES 8 E 481 LEU THR PRO LEU CYS VAL THR LEU GLN CYS THR ASN VAL
SEQRES 9 E 481 THR ASN ASN ILE THR ASP ASP MET ARG GLY GLU LEU LYS
SEQRES 10 E 481 ASN CYS SER PHE ASN MET THR THR GLU LEU ARG ASP LYS
SEQRES 11 E 481 LYS GLN LYS VAL TYR SER LEU PHE TYR ARG LEU ASP VAL
SEQRES 12 E 481 VAL GLN ILE ASN GLU ASN GLN GLY ASN ARG SER ASN ASN
SEQRES 13 E 481 SER ASN LYS GLU TYR ARG LEU ILE ASN CYS ASN THR SER
SEQRES 14 E 481 ALA ILE THR GLN ALA CYS PRO LYS VAL SER PHE GLU PRO
SEQRES 15 E 481 ILE PRO ILE HIS TYR CYS ALA PRO ALA GLY PHE ALA ILE
SEQRES 16 E 481 LEU LYS CYS LYS ASP LYS LYS PHE ASN GLY THR GLY PRO
SEQRES 17 E 481 CYS PRO SER VAL SER THR VAL GLN CYS THR HIS GLY ILE
SEQRES 18 E 481 LYS PRO VAL VAL SER THR GLN LEU LEU LEU ASN GLY SER
SEQRES 19 E 481 LEU ALA GLU GLU GLU VAL MET ILE ARG SER GLU ASN ILE
SEQRES 20 E 481 THR ASN ASN ALA LYS ASN ILE LEU VAL GLN PHE ASN THR
SEQRES 21 E 481 PRO VAL GLN ILE ASN CYS THR ARG PRO ASN ASN ASN THR
SEQRES 22 E 481 ARG LYS SER ILE ARG ILE GLY PRO GLY GLN ALA PHE TYR
SEQRES 23 E 481 ALA THR GLY ASP ILE ILE GLY ASP ILE ARG GLN ALA HIS
SEQRES 24 E 481 CYS ASN VAL SER LYS ALA THR TRP ASN GLU THR LEU GLY
SEQRES 25 E 481 LYS VAL VAL LYS GLN LEU ARG LYS HIS PHE GLY ASN ASN
SEQRES 26 E 481 THR ILE ILE ARG PHE ALA ASN SER SER GLY GLY ASP LEU
SEQRES 27 E 481 GLU VAL THR THR HIS SER PHE ASN CYS GLY GLY GLU PHE
SEQRES 28 E 481 PHE TYR CYS ASN THR SER GLY LEU PHE ASN SER THR TRP
SEQRES 29 E 481 ILE SER ASN THR SER VAL GLN GLY SER ASN SER THR GLY
SEQRES 30 E 481 SER ASN ASP SER ILE THR LEU PRO CYS ARG ILE LYS GLN
SEQRES 31 E 481 ILE ILE ASN MET TRP GLN ARG ILE GLY GLN ALA MET TYR
SEQRES 32 E 481 ALA PRO PRO ILE GLN GLY VAL ILE ARG CYS VAL SER ASN
SEQRES 33 E 481 ILE THR GLY LEU ILE LEU THR ARG ASP GLY GLY SER THR
SEQRES 34 E 481 ASN SER THR THR GLU THR PHE ARG PRO GLY GLY GLY ASP
SEQRES 35 E 481 MET ARG ASP ASN TRP ARG SER GLU LEU TYR LYS TYR LYS
SEQRES 36 E 481 VAL VAL LYS ILE GLU PRO LEU GLY VAL ALA PRO THR ARG
SEQRES 37 E 481 CYS LYS ARG ARG VAL VAL GLY ARG ARG ARG ARG ARG ARG
SEQRES 1 F 481 ALA GLU ASN LEU TRP VAL THR VAL TYR TYR GLY VAL PRO
SEQRES 2 F 481 VAL TRP LYS ASP ALA GLU THR THR LEU PHE CYS ALA SER
SEQRES 3 F 481 ASP ALA LYS ALA TYR GLU THR GLU LYS HIS ASN VAL TRP
SEQRES 4 F 481 ALA THR HIS ALA CYS VAL PRO THR ASP PRO ASN PRO GLN
SEQRES 5 F 481 GLU ILE HIS LEU GLU ASN VAL THR GLU GLU PHE ASN MET
SEQRES 6 F 481 TRP LYS ASN ASN MET VAL GLU GLN MET HIS THR ASP ILE
SEQRES 7 F 481 ILE SER LEU TRP ASP GLN SER LEU LYS PRO CYS VAL LYS
SEQRES 8 F 481 LEU THR PRO LEU CYS VAL THR LEU GLN CYS THR ASN VAL
SEQRES 9 F 481 THR ASN ASN ILE THR ASP ASP MET ARG GLY GLU LEU LYS
SEQRES 10 F 481 ASN CYS SER PHE ASN MET THR THR GLU LEU ARG ASP LYS
SEQRES 11 F 481 LYS GLN LYS VAL TYR SER LEU PHE TYR ARG LEU ASP VAL
SEQRES 12 F 481 VAL GLN ILE ASN GLU ASN GLN GLY ASN ARG SER ASN ASN
SEQRES 13 F 481 SER ASN LYS GLU TYR ARG LEU ILE ASN CYS ASN THR SER
SEQRES 14 F 481 ALA ILE THR GLN ALA CYS PRO LYS VAL SER PHE GLU PRO
SEQRES 15 F 481 ILE PRO ILE HIS TYR CYS ALA PRO ALA GLY PHE ALA ILE
SEQRES 16 F 481 LEU LYS CYS LYS ASP LYS LYS PHE ASN GLY THR GLY PRO
SEQRES 17 F 481 CYS PRO SER VAL SER THR VAL GLN CYS THR HIS GLY ILE
SEQRES 18 F 481 LYS PRO VAL VAL SER THR GLN LEU LEU LEU ASN GLY SER
SEQRES 19 F 481 LEU ALA GLU GLU GLU VAL MET ILE ARG SER GLU ASN ILE
SEQRES 20 F 481 THR ASN ASN ALA LYS ASN ILE LEU VAL GLN PHE ASN THR
SEQRES 21 F 481 PRO VAL GLN ILE ASN CYS THR ARG PRO ASN ASN ASN THR
SEQRES 22 F 481 ARG LYS SER ILE ARG ILE GLY PRO GLY GLN ALA PHE TYR
SEQRES 23 F 481 ALA THR GLY ASP ILE ILE GLY ASP ILE ARG GLN ALA HIS
SEQRES 24 F 481 CYS ASN VAL SER LYS ALA THR TRP ASN GLU THR LEU GLY
SEQRES 25 F 481 LYS VAL VAL LYS GLN LEU ARG LYS HIS PHE GLY ASN ASN
SEQRES 26 F 481 THR ILE ILE ARG PHE ALA ASN SER SER GLY GLY ASP LEU
SEQRES 27 F 481 GLU VAL THR THR HIS SER PHE ASN CYS GLY GLY GLU PHE
SEQRES 28 F 481 PHE TYR CYS ASN THR SER GLY LEU PHE ASN SER THR TRP
SEQRES 29 F 481 ILE SER ASN THR SER VAL GLN GLY SER ASN SER THR GLY
SEQRES 30 F 481 SER ASN ASP SER ILE THR LEU PRO CYS ARG ILE LYS GLN
SEQRES 31 F 481 ILE ILE ASN MET TRP GLN ARG ILE GLY GLN ALA MET TYR
SEQRES 32 F 481 ALA PRO PRO ILE GLN GLY VAL ILE ARG CYS VAL SER ASN
SEQRES 33 F 481 ILE THR GLY LEU ILE LEU THR ARG ASP GLY GLY SER THR
SEQRES 34 F 481 ASN SER THR THR GLU THR PHE ARG PRO GLY GLY GLY ASP
SEQRES 35 F 481 MET ARG ASP ASN TRP ARG SER GLU LEU TYR LYS TYR LYS
SEQRES 36 F 481 VAL VAL LYS ILE GLU PRO LEU GLY VAL ALA PRO THR ARG
SEQRES 37 F 481 CYS LYS ARG ARG VAL VAL GLY ARG ARG ARG ARG ARG ARG
SEQRES 1 G 192 LYS LYS VAL VAL LEU GLY LYS LYS GLY ASP THR VAL GLU
SEQRES 2 G 192 LEU THR CYS THR ALA SER GLN LYS LYS SER ILE GLN PHE
SEQRES 3 G 192 HIS TRP LYS ASN SER ASN GLN ILE LYS ILE LEU GLY ASN
SEQRES 4 G 192 GLN GLY SER PHE LEU THR LYS GLY PRO SER LYS LEU ASN
SEQRES 5 G 192 ASP ARG ALA ASP SER ARG ARG SER LEU TRP ASP GLN GLY
SEQRES 6 G 192 ASN PHE PRO LEU ILE ILE LYS ASN LEU LYS ILE GLU ASP
SEQRES 7 G 192 SER ASP THR TYR ILE CYS GLU VAL GLU ASP GLN LYS GLU
SEQRES 8 G 192 GLU VAL GLN LEU LEU VAL PHE GLY LEU THR ALA ASN SER
SEQRES 9 G 192 ASP THR HIS LEU LEU GLN GLY GLN SER LEU THR LEU THR
SEQRES 10 G 192 LEU GLU SER PRO PRO GLY SER SER PRO SER VAL GLN CYS
SEQRES 11 G 192 ARG SER PRO ARG GLY LYS ASN ILE GLN GLY GLY LYS THR
SEQRES 12 G 192 LEU SER VAL SER GLN LEU GLU LEU GLN ASP SER GLY THR
SEQRES 13 G 192 TRP THR CYS THR VAL LEU GLN ASN GLN LYS LYS VAL GLU
SEQRES 14 G 192 PHE LYS ILE ASP ILE VAL VAL LEU ALA PHE GLN LYS ALA
SEQRES 15 G 192 ILE ASP GLY ARG HIS HIS HIS HIS HIS HIS
SEQRES 1 H 192 LYS LYS VAL VAL LEU GLY LYS LYS GLY ASP THR VAL GLU
SEQRES 2 H 192 LEU THR CYS THR ALA SER GLN LYS LYS SER ILE GLN PHE
SEQRES 3 H 192 HIS TRP LYS ASN SER ASN GLN ILE LYS ILE LEU GLY ASN
SEQRES 4 H 192 GLN GLY SER PHE LEU THR LYS GLY PRO SER LYS LEU ASN
SEQRES 5 H 192 ASP ARG ALA ASP SER ARG ARG SER LEU TRP ASP GLN GLY
SEQRES 6 H 192 ASN PHE PRO LEU ILE ILE LYS ASN LEU LYS ILE GLU ASP
SEQRES 7 H 192 SER ASP THR TYR ILE CYS GLU VAL GLU ASP GLN LYS GLU
SEQRES 8 H 192 GLU VAL GLN LEU LEU VAL PHE GLY LEU THR ALA ASN SER
SEQRES 9 H 192 ASP THR HIS LEU LEU GLN GLY GLN SER LEU THR LEU THR
SEQRES 10 H 192 LEU GLU SER PRO PRO GLY SER SER PRO SER VAL GLN CYS
SEQRES 11 H 192 ARG SER PRO ARG GLY LYS ASN ILE GLN GLY GLY LYS THR
SEQRES 12 H 192 LEU SER VAL SER GLN LEU GLU LEU GLN ASP SER GLY THR
SEQRES 13 H 192 TRP THR CYS THR VAL LEU GLN ASN GLN LYS LYS VAL GLU
SEQRES 14 H 192 PHE LYS ILE ASP ILE VAL VAL LEU ALA PHE GLN LYS ALA
SEQRES 15 H 192 ILE ASP GLY ARG HIS HIS HIS HIS HIS HIS
SEQRES 1 I 192 LYS LYS VAL VAL LEU GLY LYS LYS GLY ASP THR VAL GLU
SEQRES 2 I 192 LEU THR CYS THR ALA SER GLN LYS LYS SER ILE GLN PHE
SEQRES 3 I 192 HIS TRP LYS ASN SER ASN GLN ILE LYS ILE LEU GLY ASN
SEQRES 4 I 192 GLN GLY SER PHE LEU THR LYS GLY PRO SER LYS LEU ASN
SEQRES 5 I 192 ASP ARG ALA ASP SER ARG ARG SER LEU TRP ASP GLN GLY
SEQRES 6 I 192 ASN PHE PRO LEU ILE ILE LYS ASN LEU LYS ILE GLU ASP
SEQRES 7 I 192 SER ASP THR TYR ILE CYS GLU VAL GLU ASP GLN LYS GLU
SEQRES 8 I 192 GLU VAL GLN LEU LEU VAL PHE GLY LEU THR ALA ASN SER
SEQRES 9 I 192 ASP THR HIS LEU LEU GLN GLY GLN SER LEU THR LEU THR
SEQRES 10 I 192 LEU GLU SER PRO PRO GLY SER SER PRO SER VAL GLN CYS
SEQRES 11 I 192 ARG SER PRO ARG GLY LYS ASN ILE GLN GLY GLY LYS THR
SEQRES 12 I 192 LEU SER VAL SER GLN LEU GLU LEU GLN ASP SER GLY THR
SEQRES 13 I 192 TRP THR CYS THR VAL LEU GLN ASN GLN LYS LYS VAL GLU
SEQRES 14 I 192 PHE LYS ILE ASP ILE VAL VAL LEU ALA PHE GLN LYS ALA
SEQRES 15 I 192 ILE ASP GLY ARG HIS HIS HIS HIS HIS HIS
SEQRES 1 J 214 ASP ILE VAL MET THR GLN SER PRO ALA THR LEU SER VAL
SEQRES 2 J 214 SER PRO GLY GLU ARG ALA THR LEU SER CYS ARG ALA SER
SEQRES 3 J 214 GLU SER VAL SER SER ASP LEU ALA TRP TYR GLN GLN LYS
SEQRES 4 J 214 PRO GLY GLN ALA PRO ARG LEU LEU ILE TYR GLY ALA SER
SEQRES 5 J 214 THR ARG ALA THR GLY VAL PRO ALA ARG PHE SER GLY SER
SEQRES 6 J 214 GLY SER GLY ALA GLU PHE THR LEU THR ILE SER SER LEU
SEQRES 7 J 214 GLN SER GLU ASP PHE ALA VAL TYR TYR CYS GLN GLN TYR
SEQRES 8 J 214 ASN ASN TRP PRO PRO ARG TYR THR PHE GLY GLN GLY THR
SEQRES 9 J 214 ARG LEU GLU ILE LYS ARG THR VAL ALA ALA PRO SER VAL
SEQRES 10 J 214 PHE ILE PHE PRO PRO SER ASP GLU GLN LEU LYS SER GLY
SEQRES 11 J 214 THR ALA SER VAL VAL CYS LEU LEU ASN ASN PHE TYR PRO
SEQRES 12 J 214 ARG GLU ALA LYS VAL GLN TRP LYS VAL ASP ASN ALA LEU
SEQRES 13 J 214 GLN SER GLY ASN SER GLN GLU SER VAL THR GLU GLN ASP
SEQRES 14 J 214 SER LYS ASP SER THR TYR SER LEU SER SER THR LEU THR
SEQRES 15 J 214 LEU SER LYS ALA ASP TYR GLU LYS HIS LYS VAL TYR ALA
SEQRES 16 J 214 CYS GLU VAL THR HIS GLN GLY LEU SER SER PRO VAL THR
SEQRES 17 J 214 LYS SER PHE ASN ARG GLY
SEQRES 1 K 229 GLU VAL GLN LEU VAL GLU SER GLY ALA GLU VAL LYS LYS
SEQRES 2 K 229 PRO GLY SER SER VAL LYS VAL SER CYS LYS ALA SER GLY
SEQRES 3 K 229 ASP THR PHE ILE ARG TYR SER PHE THR TRP VAL ARG GLN
SEQRES 4 K 229 ALA PRO GLY GLN GLY LEU GLU TRP MET GLY ARG ILE ILE
SEQRES 5 K 229 THR ILE LEU ASP VAL ALA HIS TYR ALA PRO HIS LEU GLN
SEQRES 6 K 229 GLY ARG VAL THR ILE THR ALA ASP LYS SER THR SER THR
SEQRES 7 K 229 VAL TYR LEU GLU LEU ARG ASN LEU ARG SER ASP ASP THR
SEQRES 8 K 229 ALA VAL TYR PHE CYS ALA GLY VAL TYR GLU GLY GLU ALA
SEQRES 9 K 229 ASP GLU GLY GLU TYR ASP ASN ASN GLY PHE LEU LYS HIS
SEQRES 10 K 229 TRP GLY GLN GLY THR LEU VAL THR VAL SER SER ALA SER
SEQRES 11 K 229 THR LYS GLY PRO SER VAL PHE PRO LEU ALA PRO SER SER
SEQRES 12 K 229 LYS SER THR SER GLY GLY THR ALA ALA LEU GLY CYS LEU
SEQRES 13 K 229 VAL LYS ASP TYR PHE PRO GLU PRO VAL THR VAL SER TRP
SEQRES 14 K 229 ASN SER GLY ALA LEU THR SER GLY VAL HIS THR PHE PRO
SEQRES 15 K 229 ALA VAL LEU GLN SER SER GLY LEU TYR SER LEU SER SER
SEQRES 16 K 229 VAL VAL THR VAL PRO SER SER SER LEU GLY THR GLN THR
SEQRES 17 K 229 TYR ILE CYS ASN VAL ASN HIS LYS PRO SER ASN THR LYS
SEQRES 18 K 229 VAL ASP LYS LYS VAL GLU PRO LYS
SEQRES 1 L 214 ASP ILE VAL MET THR GLN SER PRO ALA THR LEU SER VAL
SEQRES 2 L 214 SER PRO GLY GLU ARG ALA THR LEU SER CYS ARG ALA SER
SEQRES 3 L 214 GLU SER VAL SER SER ASP LEU ALA TRP TYR GLN GLN LYS
SEQRES 4 L 214 PRO GLY GLN ALA PRO ARG LEU LEU ILE TYR GLY ALA SER
SEQRES 5 L 214 THR ARG ALA THR GLY VAL PRO ALA ARG PHE SER GLY SER
SEQRES 6 L 214 GLY SER GLY ALA GLU PHE THR LEU THR ILE SER SER LEU
SEQRES 7 L 214 GLN SER GLU ASP PHE ALA VAL TYR TYR CYS GLN GLN TYR
SEQRES 8 L 214 ASN ASN TRP PRO PRO ARG TYR THR PHE GLY GLN GLY THR
SEQRES 9 L 214 ARG LEU GLU ILE LYS ARG THR VAL ALA ALA PRO SER VAL
SEQRES 10 L 214 PHE ILE PHE PRO PRO SER ASP GLU GLN LEU LYS SER GLY
SEQRES 11 L 214 THR ALA SER VAL VAL CYS LEU LEU ASN ASN PHE TYR PRO
SEQRES 12 L 214 ARG GLU ALA LYS VAL GLN TRP LYS VAL ASP ASN ALA LEU
SEQRES 13 L 214 GLN SER GLY ASN SER GLN GLU SER VAL THR GLU GLN ASP
SEQRES 14 L 214 SER LYS ASP SER THR TYR SER LEU SER SER THR LEU THR
SEQRES 15 L 214 LEU SER LYS ALA ASP TYR GLU LYS HIS LYS VAL TYR ALA
SEQRES 16 L 214 CYS GLU VAL THR HIS GLN GLY LEU SER SER PRO VAL THR
SEQRES 17 L 214 LYS SER PHE ASN ARG GLY
SEQRES 1 M 229 GLU VAL GLN LEU VAL GLU SER GLY ALA GLU VAL LYS LYS
SEQRES 2 M 229 PRO GLY SER SER VAL LYS VAL SER CYS LYS ALA SER GLY
SEQRES 3 M 229 ASP THR PHE ILE ARG TYR SER PHE THR TRP VAL ARG GLN
SEQRES 4 M 229 ALA PRO GLY GLN GLY LEU GLU TRP MET GLY ARG ILE ILE
SEQRES 5 M 229 THR ILE LEU ASP VAL ALA HIS TYR ALA PRO HIS LEU GLN
SEQRES 6 M 229 GLY ARG VAL THR ILE THR ALA ASP LYS SER THR SER THR
SEQRES 7 M 229 VAL TYR LEU GLU LEU ARG ASN LEU ARG SER ASP ASP THR
SEQRES 8 M 229 ALA VAL TYR PHE CYS ALA GLY VAL TYR GLU GLY GLU ALA
SEQRES 9 M 229 ASP GLU GLY GLU TYR ASP ASN ASN GLY PHE LEU LYS HIS
SEQRES 10 M 229 TRP GLY GLN GLY THR LEU VAL THR VAL SER SER ALA SER
SEQRES 11 M 229 THR LYS GLY PRO SER VAL PHE PRO LEU ALA PRO SER SER
SEQRES 12 M 229 LYS SER THR SER GLY GLY THR ALA ALA LEU GLY CYS LEU
SEQRES 13 M 229 VAL LYS ASP TYR PHE PRO GLU PRO VAL THR VAL SER TRP
SEQRES 14 M 229 ASN SER GLY ALA LEU THR SER GLY VAL HIS THR PHE PRO
SEQRES 15 M 229 ALA VAL LEU GLN SER SER GLY LEU TYR SER LEU SER SER
SEQRES 16 M 229 VAL VAL THR VAL PRO SER SER SER LEU GLY THR GLN THR
SEQRES 17 M 229 TYR ILE CYS ASN VAL ASN HIS LYS PRO SER ASN THR LYS
SEQRES 18 M 229 VAL ASP LYS LYS VAL GLU PRO LYS
SEQRES 1 N 214 ASP ILE VAL MET THR GLN SER PRO ALA THR LEU SER VAL
SEQRES 2 N 214 SER PRO GLY GLU ARG ALA THR LEU SER CYS ARG ALA SER
SEQRES 3 N 214 GLU SER VAL SER SER ASP LEU ALA TRP TYR GLN GLN LYS
SEQRES 4 N 214 PRO GLY GLN ALA PRO ARG LEU LEU ILE TYR GLY ALA SER
SEQRES 5 N 214 THR ARG ALA THR GLY VAL PRO ALA ARG PHE SER GLY SER
SEQRES 6 N 214 GLY SER GLY ALA GLU PHE THR LEU THR ILE SER SER LEU
SEQRES 7 N 214 GLN SER GLU ASP PHE ALA VAL TYR TYR CYS GLN GLN TYR
SEQRES 8 N 214 ASN ASN TRP PRO PRO ARG TYR THR PHE GLY GLN GLY THR
SEQRES 9 N 214 ARG LEU GLU ILE LYS ARG THR VAL ALA ALA PRO SER VAL
SEQRES 10 N 214 PHE ILE PHE PRO PRO SER ASP GLU GLN LEU LYS SER GLY
SEQRES 11 N 214 THR ALA SER VAL VAL CYS LEU LEU ASN ASN PHE TYR PRO
SEQRES 12 N 214 ARG GLU ALA LYS VAL GLN TRP LYS VAL ASP ASN ALA LEU
SEQRES 13 N 214 GLN SER GLY ASN SER GLN GLU SER VAL THR GLU GLN ASP
SEQRES 14 N 214 SER LYS ASP SER THR TYR SER LEU SER SER THR LEU THR
SEQRES 15 N 214 LEU SER LYS ALA ASP TYR GLU LYS HIS LYS VAL TYR ALA
SEQRES 16 N 214 CYS GLU VAL THR HIS GLN GLY LEU SER SER PRO VAL THR
SEQRES 17 N 214 LYS SER PHE ASN ARG GLY
SEQRES 1 O 229 GLU VAL GLN LEU VAL GLU SER GLY ALA GLU VAL LYS LYS
SEQRES 2 O 229 PRO GLY SER SER VAL LYS VAL SER CYS LYS ALA SER GLY
SEQRES 3 O 229 ASP THR PHE ILE ARG TYR SER PHE THR TRP VAL ARG GLN
SEQRES 4 O 229 ALA PRO GLY GLN GLY LEU GLU TRP MET GLY ARG ILE ILE
SEQRES 5 O 229 THR ILE LEU ASP VAL ALA HIS TYR ALA PRO HIS LEU GLN
SEQRES 6 O 229 GLY ARG VAL THR ILE THR ALA ASP LYS SER THR SER THR
SEQRES 7 O 229 VAL TYR LEU GLU LEU ARG ASN LEU ARG SER ASP ASP THR
SEQRES 8 O 229 ALA VAL TYR PHE CYS ALA GLY VAL TYR GLU GLY GLU ALA
SEQRES 9 O 229 ASP GLU GLY GLU TYR ASP ASN ASN GLY PHE LEU LYS HIS
SEQRES 10 O 229 TRP GLY GLN GLY THR LEU VAL THR VAL SER SER ALA SER
SEQRES 11 O 229 THR LYS GLY PRO SER VAL PHE PRO LEU ALA PRO SER SER
SEQRES 12 O 229 LYS SER THR SER GLY GLY THR ALA ALA LEU GLY CYS LEU
SEQRES 13 O 229 VAL LYS ASP TYR PHE PRO GLU PRO VAL THR VAL SER TRP
SEQRES 14 O 229 ASN SER GLY ALA LEU THR SER GLY VAL HIS THR PHE PRO
SEQRES 15 O 229 ALA VAL LEU GLN SER SER GLY LEU TYR SER LEU SER SER
SEQRES 16 O 229 VAL VAL THR VAL PRO SER SER SER LEU GLY THR GLN THR
SEQRES 17 O 229 TYR ILE CYS ASN VAL ASN HIS LYS PRO SER ASN THR LYS
SEQRES 18 O 229 VAL ASP LYS LYS VAL GLU PRO LYS
SEQRES 1 P 244 GLN ILE HIS LEU VAL GLN SER GLY THR GLU VAL LYS LYS
SEQRES 2 P 244 PRO GLY SER SER VAL THR VAL SER CYS LYS ALA TYR GLY
SEQRES 3 P 244 VAL ASN THR PHE GLY LEU TYR ALA VAL ASN TRP VAL ARG
SEQRES 4 P 244 GLN ALA PRO GLY GLN SER LEU GLU TYR ILE GLY GLN ILE
SEQRES 5 P 244 TRP ARG TRP LYS SER SER ALA SER HIS HIS PHE ARG GLY
SEQRES 6 P 244 ARG VAL LEU ILE SER ALA VAL ASP LEU THR GLY SER SER
SEQRES 7 P 244 PRO PRO ILE SER SER LEU GLU ILE LYS ASN LEU THR SER
SEQRES 8 P 244 ASP ASP THR ALA VAL TYR PHE CYS THR THR THR SER THR
SEQRES 9 P 244 TYR ASP LYS TRP SER GLY LEU HIS HIS ASP GLY VAL MET
SEQRES 10 P 244 ALA PHE SER SER TRP GLY GLN GLY THR LEU ILE SER VAL
SEQRES 11 P 244 SER ALA ALA SER THR LYS GLY PRO SER VAL PHE PRO LEU
SEQRES 12 P 244 ALA PRO SER SER LYS SER THR SER GLY GLY THR ALA ALA
SEQRES 13 P 244 LEU GLY CYS LEU VAL LYS ASP TYR PHE PRO GLU PRO VAL
SEQRES 14 P 244 THR VAL SER TRP ASN SER GLY ALA LEU THR SER GLY VAL
SEQRES 15 P 244 HIS THR PHE PRO ALA VAL LEU GLN SER SER GLY LEU TYR
SEQRES 16 P 244 SER LEU SER SER VAL VAL THR VAL PRO SER SER SER LEU
SEQRES 17 P 244 GLY THR GLN THR TYR ILE CYS ASN VAL ASN HIS LYS PRO
SEQRES 18 P 244 SER ASN THR LYS VAL ASP LYS ARG VAL GLU PRO LYS SER
SEQRES 19 P 244 CYS ASP LYS THR HIS HIS HIS HIS HIS HIS
SEQRES 1 Q 215 ASP ILE GLN MET THR GLN SER PRO SER THR LEU SER ALA
SEQRES 2 Q 215 SER ILE GLY ASP THR VAL ARG ILE SER CYS ARG ALA SER
SEQRES 3 Q 215 GLN SER ILE THR GLY ASN TRP VAL ALA TRP TYR GLN GLN
SEQRES 4 Q 215 ARG PRO GLY LYS ALA PRO ARG LEU LEU ILE TYR ARG GLY
SEQRES 5 Q 215 ALA ALA LEU LEU GLY GLY VAL PRO SER ARG PHE SER GLY
SEQRES 6 Q 215 SER ALA ALA GLY THR ASP PHE THR LEU THR ILE GLY ASN
SEQRES 7 Q 215 LEU GLN ALA GLU ASP PHE GLY THR PHE TYR CYS GLN GLN
SEQRES 8 Q 215 TYR ASP THR TYR PRO GLY THR PHE GLY GLN GLY THR LYS
SEQRES 9 Q 215 VAL GLU VAL LYS ARG THR VAL ALA ALA PRO SER VAL PHE
SEQRES 10 Q 215 ILE PHE PRO PRO SER ASP GLU GLN LEU LYS SER GLY THR
SEQRES 11 Q 215 ALA SER VAL VAL CYS LEU LEU ASN ASN PHE TYR PRO ARG
SEQRES 12 Q 215 GLU ALA LYS VAL GLN TRP LYS VAL ASP ASN ALA LEU GLN
SEQRES 13 Q 215 SER GLY ASN SER GLN GLU SER VAL THR GLU GLN ASP SER
SEQRES 14 Q 215 LYS ASP SER THR TYR SER LEU SER SER THR LEU THR LEU
SEQRES 15 Q 215 SER LYS ALA ASP TYR GLU LYS HIS LYS VAL TYR ALA CYS
SEQRES 16 Q 215 GLU VAL THR HIS GLN GLY LEU SER SER PRO VAL THR LYS
SEQRES 17 Q 215 SER PHE ASN ARG GLY GLU CYS
SEQRES 1 R 244 GLN ILE HIS LEU VAL GLN SER GLY THR GLU VAL LYS LYS
SEQRES 2 R 244 PRO GLY SER SER VAL THR VAL SER CYS LYS ALA TYR GLY
SEQRES 3 R 244 VAL ASN THR PHE GLY LEU TYR ALA VAL ASN TRP VAL ARG
SEQRES 4 R 244 GLN ALA PRO GLY GLN SER LEU GLU TYR ILE GLY GLN ILE
SEQRES 5 R 244 TRP ARG TRP LYS SER SER ALA SER HIS HIS PHE ARG GLY
SEQRES 6 R 244 ARG VAL LEU ILE SER ALA VAL ASP LEU THR GLY SER SER
SEQRES 7 R 244 PRO PRO ILE SER SER LEU GLU ILE LYS ASN LEU THR SER
SEQRES 8 R 244 ASP ASP THR ALA VAL TYR PHE CYS THR THR THR SER THR
SEQRES 9 R 244 TYR ASP LYS TRP SER GLY LEU HIS HIS ASP GLY VAL MET
SEQRES 10 R 244 ALA PHE SER SER TRP GLY GLN GLY THR LEU ILE SER VAL
SEQRES 11 R 244 SER ALA ALA SER THR LYS GLY PRO SER VAL PHE PRO LEU
SEQRES 12 R 244 ALA PRO SER SER LYS SER THR SER GLY GLY THR ALA ALA
SEQRES 13 R 244 LEU GLY CYS LEU VAL LYS ASP TYR PHE PRO GLU PRO VAL
SEQRES 14 R 244 THR VAL SER TRP ASN SER GLY ALA LEU THR SER GLY VAL
SEQRES 15 R 244 HIS THR PHE PRO ALA VAL LEU GLN SER SER GLY LEU TYR
SEQRES 16 R 244 SER LEU SER SER VAL VAL THR VAL PRO SER SER SER LEU
SEQRES 17 R 244 GLY THR GLN THR TYR ILE CYS ASN VAL ASN HIS LYS PRO
SEQRES 18 R 244 SER ASN THR LYS VAL ASP LYS ARG VAL GLU PRO LYS SER
SEQRES 19 R 244 CYS ASP LYS THR HIS HIS HIS HIS HIS HIS
SEQRES 1 S 215 ASP ILE GLN MET THR GLN SER PRO SER THR LEU SER ALA
SEQRES 2 S 215 SER ILE GLY ASP THR VAL ARG ILE SER CYS ARG ALA SER
SEQRES 3 S 215 GLN SER ILE THR GLY ASN TRP VAL ALA TRP TYR GLN GLN
SEQRES 4 S 215 ARG PRO GLY LYS ALA PRO ARG LEU LEU ILE TYR ARG GLY
SEQRES 5 S 215 ALA ALA LEU LEU GLY GLY VAL PRO SER ARG PHE SER GLY
SEQRES 6 S 215 SER ALA ALA GLY THR ASP PHE THR LEU THR ILE GLY ASN
SEQRES 7 S 215 LEU GLN ALA GLU ASP PHE GLY THR PHE TYR CYS GLN GLN
SEQRES 8 S 215 TYR ASP THR TYR PRO GLY THR PHE GLY GLN GLY THR LYS
SEQRES 9 S 215 VAL GLU VAL LYS ARG THR VAL ALA ALA PRO SER VAL PHE
SEQRES 10 S 215 ILE PHE PRO PRO SER ASP GLU GLN LEU LYS SER GLY THR
SEQRES 11 S 215 ALA SER VAL VAL CYS LEU LEU ASN ASN PHE TYR PRO ARG
SEQRES 12 S 215 GLU ALA LYS VAL GLN TRP LYS VAL ASP ASN ALA LEU GLN
SEQRES 13 S 215 SER GLY ASN SER GLN GLU SER VAL THR GLU GLN ASP SER
SEQRES 14 S 215 LYS ASP SER THR TYR SER LEU SER SER THR LEU THR LEU
SEQRES 15 S 215 SER LYS ALA ASP TYR GLU LYS HIS LYS VAL TYR ALA CYS
SEQRES 16 S 215 GLU VAL THR HIS GLN GLY LEU SER SER PRO VAL THR LYS
SEQRES 17 S 215 SER PHE ASN ARG GLY GLU CYS
SEQRES 1 T 244 GLN ILE HIS LEU VAL GLN SER GLY THR GLU VAL LYS LYS
SEQRES 2 T 244 PRO GLY SER SER VAL THR VAL SER CYS LYS ALA TYR GLY
SEQRES 3 T 244 VAL ASN THR PHE GLY LEU TYR ALA VAL ASN TRP VAL ARG
SEQRES 4 T 244 GLN ALA PRO GLY GLN SER LEU GLU TYR ILE GLY GLN ILE
SEQRES 5 T 244 TRP ARG TRP LYS SER SER ALA SER HIS HIS PHE ARG GLY
SEQRES 6 T 244 ARG VAL LEU ILE SER ALA VAL ASP LEU THR GLY SER SER
SEQRES 7 T 244 PRO PRO ILE SER SER LEU GLU ILE LYS ASN LEU THR SER
SEQRES 8 T 244 ASP ASP THR ALA VAL TYR PHE CYS THR THR THR SER THR
SEQRES 9 T 244 TYR ASP LYS TRP SER GLY LEU HIS HIS ASP GLY VAL MET
SEQRES 10 T 244 ALA PHE SER SER TRP GLY GLN GLY THR LEU ILE SER VAL
SEQRES 11 T 244 SER ALA ALA SER THR LYS GLY PRO SER VAL PHE PRO LEU
SEQRES 12 T 244 ALA PRO SER SER LYS SER THR SER GLY GLY THR ALA ALA
SEQRES 13 T 244 LEU GLY CYS LEU VAL LYS ASP TYR PHE PRO GLU PRO VAL
SEQRES 14 T 244 THR VAL SER TRP ASN SER GLY ALA LEU THR SER GLY VAL
SEQRES 15 T 244 HIS THR PHE PRO ALA VAL LEU GLN SER SER GLY LEU TYR
SEQRES 16 T 244 SER LEU SER SER VAL VAL THR VAL PRO SER SER SER LEU
SEQRES 17 T 244 GLY THR GLN THR TYR ILE CYS ASN VAL ASN HIS LYS PRO
SEQRES 18 T 244 SER ASN THR LYS VAL ASP LYS ARG VAL GLU PRO LYS SER
SEQRES 19 T 244 CYS ASP LYS THR HIS HIS HIS HIS HIS HIS
SEQRES 1 U 215 ASP ILE GLN MET THR GLN SER PRO SER THR LEU SER ALA
SEQRES 2 U 215 SER ILE GLY ASP THR VAL ARG ILE SER CYS ARG ALA SER
SEQRES 3 U 215 GLN SER ILE THR GLY ASN TRP VAL ALA TRP TYR GLN GLN
SEQRES 4 U 215 ARG PRO GLY LYS ALA PRO ARG LEU LEU ILE TYR ARG GLY
SEQRES 5 U 215 ALA ALA LEU LEU GLY GLY VAL PRO SER ARG PHE SER GLY
SEQRES 6 U 215 SER ALA ALA GLY THR ASP PHE THR LEU THR ILE GLY ASN
SEQRES 7 U 215 LEU GLN ALA GLU ASP PHE GLY THR PHE TYR CYS GLN GLN
SEQRES 8 U 215 TYR ASP THR TYR PRO GLY THR PHE GLY GLN GLY THR LYS
SEQRES 9 U 215 VAL GLU VAL LYS ARG THR VAL ALA ALA PRO SER VAL PHE
SEQRES 10 U 215 ILE PHE PRO PRO SER ASP GLU GLN LEU LYS SER GLY THR
SEQRES 11 U 215 ALA SER VAL VAL CYS LEU LEU ASN ASN PHE TYR PRO ARG
SEQRES 12 U 215 GLU ALA LYS VAL GLN TRP LYS VAL ASP ASN ALA LEU GLN
SEQRES 13 U 215 SER GLY ASN SER GLN GLU SER VAL THR GLU GLN ASP SER
SEQRES 14 U 215 LYS ASP SER THR TYR SER LEU SER SER THR LEU THR LEU
SEQRES 15 U 215 SER LYS ALA ASP TYR GLU LYS HIS LYS VAL TYR ALA CYS
SEQRES 16 U 215 GLU VAL THR HIS GLN GLY LEU SER SER PRO VAL THR LYS
SEQRES 17 U 215 SER PHE ASN ARG GLY GLU CYS
HET NAG V 1 14
HET NAG V 2 14
HET NAG W 1 14
HET NAG W 2 14
HET NAG X 1 14
HET NAG X 2 14
HET NAG Y 1 14
HET NAG Y 2 14
HET BMA Y 3 11
HET MAN Y 4 11
HET MAN Y 5 11
HET MAN Y 6 11
HET MAN Y 7 11
HET MAN Y 8 11
HET MAN Y 9 11
HET MAN Y 10 11
HET NAG Z 1 14
HET NAG Z 2 14
HET BMA Z 3 11
HET MAN Z 4 11
HET MAN Z 5 11
HET NAG a 1 14
HET NAG a 2 14
HET BMA a 3 11
HET MAN a 4 11
HET MAN a 5 11
HET NAG b 1 14
HET NAG b 2 14
HET NAG c 1 14
HET NAG c 2 14
HET BMA c 3 11
HET MAN c 4 11
HET MAN c 5 11
HET MAN c 6 11
HET MAN c 7 11
HET MAN c 8 11
HET MAN c 9 11
HET MAN c 10 11
HET NAG d 1 14
HET NAG d 2 14
HET BMA d 3 11
HET MAN d 4 11
HET MAN d 5 11
HET NAG e 1 14
HET NAG e 2 14
HET BMA e 3 11
HET MAN e 4 11
HET MAN e 5 11
HET NAG f 1 14
HET NAG f 2 14
HET NAG g 1 14
HET NAG g 2 14
HET BMA g 3 11
HET MAN g 4 11
HET MAN g 5 11
HET MAN g 6 11
HET MAN g 7 11
HET MAN g 8 11
HET MAN g 9 11
HET MAN g 10 11
HET NAG h 1 14
HET NAG h 2 14
HET BMA h 3 11
HET MAN h 4 11
HET MAN h 5 11
HET NAG i 1 14
HET NAG i 2 14
HET BMA i 3 11
HET MAN i 4 11
HET MAN i 5 11
HET NAG j 1 14
HET NAG j 2 14
HET NAG D 621 14
HET NAG D 622 14
HET NAG D 623 14
HET NAG D 624 14
HET NAG D 627 14
HET NAG D 628 14
HET NAG E 621 14
HET NAG E 622 14
HET NAG E 623 14
HET NAG E 624 14
HET NAG E 627 14
HET NAG E 628 14
HET NAG F 621 14
HET NAG F 622 14
HET NAG F 623 14
HET NAG F 624 14
HET NAG F 627 14
HET NAG F 628 14
HETNAM NAG 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE
HETNAM BMA BETA-D-MANNOPYRANOSE
HETNAM MAN ALPHA-D-MANNOPYRANOSE
FORMUL 22 NAG 48(C8 H15 N O6)
FORMUL 25 BMA 9(C6 H12 O6)
FORMUL 25 MAN 33(C6 H12 O6)
HELIX 1 AA1 LEU A 520 ALA A 526 5 7
HELIX 2 AA2 THR A 529 LEU A 544 1 16
HELIX 3 AA3 LEU A 565 LEU A 593 1 29
HELIX 4 AA4 ASN A 618 MET A 626 1 9
HELIX 5 AA5 THR A 627 ILE A 635 1 9
HELIX 6 AA6 TYR A 638 SER A 649 1 12
HELIX 7 AA7 LEU B 520 ALA B 526 5 7
HELIX 8 AA8 THR B 529 LEU B 544 1 16
HELIX 9 AA9 LEU B 565 LEU B 593 1 29
HELIX 10 AB1 ASN B 618 MET B 626 1 9
HELIX 11 AB2 THR B 627 ILE B 635 1 9
HELIX 12 AB3 TYR B 638 SER B 649 1 12
HELIX 13 AB4 LEU C 520 ALA C 526 5 7
HELIX 14 AB5 THR C 529 LEU C 544 1 16
HELIX 15 AB6 LEU C 565 LEU C 593 1 29
HELIX 16 AB7 ASN C 618 MET C 626 1 9
HELIX 17 AB8 THR C 627 ILE C 635 1 9
HELIX 18 AB9 TYR C 638 SER C 649 1 12
HELIX 19 AC1 GLU D 64 CYS D 74 1 11
HELIX 20 AC2 ASN D 94 ASN D 98 5 5
HELIX 21 AC3 MET D 100 LEU D 116 1 17
HELIX 22 AC4 THR D 337 GLY D 354 1 18
HELIX 23 AC5 ASP D 368 THR D 373 1 6
HELIX 24 AC6 MET D 475 ARG D 480 1 6
HELIX 25 AC7 GLU E 64 CYS E 74 1 11
HELIX 26 AC8 ASN E 94 ASN E 98 5 5
HELIX 27 AC9 MET E 100 LEU E 116 1 17
HELIX 28 AD1 THR E 337 GLY E 354 1 18
HELIX 29 AD2 ASP E 368 THR E 373 1 6
HELIX 30 AD3 MET E 475 ARG E 480 1 6
HELIX 31 AD4 GLU F 64 CYS F 74 1 11
HELIX 32 AD5 ASN F 94 ASN F 98 5 5
HELIX 33 AD6 MET F 100 LEU F 116 1 17
HELIX 34 AD7 THR F 337 GLY F 354 1 18
HELIX 35 AD8 ASP F 368 THR F 373 1 6
HELIX 36 AD9 MET F 475 ARG F 480 1 6
HELIX 37 AE1 ARG G 58 GLN G 64 5 7
HELIX 38 AE2 ARG H 58 GLN H 64 5 7
HELIX 39 AE3 ARG I 58 GLN I 64 5 7
HELIX 40 AE4 THR K 28 ILE K 30 5 3
HELIX 41 AE5 ARG K 87 THR K 91 5 5
HELIX 42 AE6 THR M 28 ILE M 30 5 3
HELIX 43 AE7 ARG M 87 THR M 91 5 5
HELIX 44 AE8 THR O 28 ILE O 30 5 3
HELIX 45 AE9 ARG O 87 THR O 91 5 5
HELIX 46 AF1 TRP P 53 LYS P 56 5 4
HELIX 47 AF2 TRP R 53 LYS R 56 5 4
HELIX 48 AF3 TRP T 53 LYS T 56 5 4
SHEET 1 AA1 4 ILE D 84 HIS D 85 0
SHEET 2 AA1 4 VAL D 242 VAL D 245 -1 O THR D 244 N ILE D 84
SHEET 3 AA1 4 PHE D 223 CYS D 228 -1 N ILE D 225 O VAL D 245
SHEET 4 AA1 4 TYR D 486 LYS D 490 -1 O VAL D 489 N ALA D 224
SHEET 1 AA2 2 GLU D 91 GLU D 92 0
SHEET 2 AA2 2 PRO D 238 CYS D 239 -1 O CYS D 239 N GLU D 91
SHEET 1 AA3 4 SER D 199 THR D 202 0
SHEET 2 AA3 4 VAL D 120 THR D 123 -1 N LYS D 121 O ILE D 201
SHEET 3 AA3 4 GLN D 432 MET D 434 -1 O GLN D 432 N LEU D 122
SHEET 4 AA3 4 ILE D 423 ASN D 425 -1 N ILE D 424 O ALA D 433
SHEET 1 AA4 4 LEU D 259 LEU D 261 0
SHEET 2 AA4 4 ILE D 443 LEU D 454 -1 O THR D 450 N LEU D 260
SHEET 3 AA4 4 ILE D 284 ARG D 298 -1 N VAL D 292 O ILE D 449
SHEET 4 AA4 4 MET D 271 ARG D 273 -1 N ARG D 273 O LEU D 285
SHEET 1 AA5 7 LEU D 259 LEU D 261 0
SHEET 2 AA5 7 ILE D 443 LEU D 454 -1 O THR D 450 N LEU D 260
SHEET 3 AA5 7 ILE D 284 ARG D 298 -1 N VAL D 292 O ILE D 449
SHEET 4 AA5 7 ALA D 329 VAL D 333 -1 O HIS D 330 N THR D 297
SHEET 5 AA5 7 ILE D 414 ILE D 420 -1 O LEU D 416 N CYS D 331
SHEET 6 AA5 7 GLU D 381 TYR D 384 -1 N TYR D 384 O ARG D 419
SHEET 7 AA5 7 SER D 375 CYS D 378 -1 N CYS D 378 O GLU D 381
SHEET 1 AA6 4 ILE E 84 HIS E 85 0
SHEET 2 AA6 4 VAL E 242 VAL E 245 -1 O THR E 244 N ILE E 84
SHEET 3 AA6 4 PHE E 223 CYS E 228 -1 N ILE E 225 O VAL E 245
SHEET 4 AA6 4 TYR E 486 LYS E 490 -1 O VAL E 489 N ALA E 224
SHEET 1 AA7 2 GLU E 91 GLU E 92 0
SHEET 2 AA7 2 PRO E 238 CYS E 239 -1 O CYS E 239 N GLU E 91
SHEET 1 AA8 4 SER E 199 THR E 202 0
SHEET 2 AA8 4 VAL E 120 THR E 123 -1 N LYS E 121 O ILE E 201
SHEET 3 AA8 4 GLN E 432 MET E 434 -1 O GLN E 432 N LEU E 122
SHEET 4 AA8 4 ILE E 423 ASN E 425 -1 N ILE E 424 O ALA E 433
SHEET 1 AA9 4 LEU E 259 LEU E 261 0
SHEET 2 AA9 4 ILE E 443 LEU E 454 -1 O THR E 450 N LEU E 260
SHEET 3 AA9 4 ILE E 284 ARG E 298 -1 N VAL E 292 O ILE E 449
SHEET 4 AA9 4 MET E 271 ARG E 273 -1 N ARG E 273 O LEU E 285
SHEET 1 AB1 7 LEU E 259 LEU E 261 0
SHEET 2 AB1 7 ILE E 443 LEU E 454 -1 O THR E 450 N LEU E 260
SHEET 3 AB1 7 ILE E 284 ARG E 298 -1 N VAL E 292 O ILE E 449
SHEET 4 AB1 7 ALA E 329 VAL E 333 -1 O HIS E 330 N THR E 297
SHEET 5 AB1 7 ILE E 414 ILE E 420 -1 O LEU E 416 N CYS E 331
SHEET 6 AB1 7 GLU E 381 TYR E 384 -1 N TYR E 384 O ARG E 419
SHEET 7 AB1 7 SER E 375 CYS E 378 -1 N CYS E 378 O GLU E 381
SHEET 1 AB2 4 ILE F 84 HIS F 85 0
SHEET 2 AB2 4 VAL F 242 VAL F 245 -1 O THR F 244 N ILE F 84
SHEET 3 AB2 4 PHE F 223 CYS F 228 -1 N ILE F 225 O VAL F 245
SHEET 4 AB2 4 TYR F 486 LYS F 490 -1 O VAL F 489 N ALA F 224
SHEET 1 AB3 2 GLU F 91 GLU F 92 0
SHEET 2 AB3 2 PRO F 238 CYS F 239 -1 O CYS F 239 N GLU F 91
SHEET 1 AB4 4 SER F 199 THR F 202 0
SHEET 2 AB4 4 VAL F 120 THR F 123 -1 N LYS F 121 O ILE F 201
SHEET 3 AB4 4 GLN F 432 MET F 434 -1 O GLN F 432 N LEU F 122
SHEET 4 AB4 4 ILE F 423 ASN F 425 -1 N ILE F 424 O ALA F 433
SHEET 1 AB5 4 LEU F 259 LEU F 261 0
SHEET 2 AB5 4 ILE F 443 LEU F 454 -1 O THR F 450 N LEU F 260
SHEET 3 AB5 4 ILE F 284 ARG F 298 -1 N VAL F 292 O ILE F 449
SHEET 4 AB5 4 MET F 271 ARG F 273 -1 N ARG F 273 O LEU F 285
SHEET 1 AB6 7 LEU F 259 LEU F 261 0
SHEET 2 AB6 7 ILE F 443 LEU F 454 -1 O THR F 450 N LEU F 260
SHEET 3 AB6 7 ILE F 284 ARG F 298 -1 N VAL F 292 O ILE F 449
SHEET 4 AB6 7 ALA F 329 VAL F 333 -1 O HIS F 330 N THR F 297
SHEET 5 AB6 7 ILE F 414 ILE F 420 -1 O LEU F 416 N CYS F 331
SHEET 6 AB6 7 GLU F 381 TYR F 384 -1 N TYR F 384 O ARG F 419
SHEET 7 AB6 7 SER F 375 CYS F 378 -1 N CYS F 378 O GLU F 381
SHEET 1 AB7 6 LYS G 2 LEU G 5 0
SHEET 2 AB7 6 GLU G 91 LEU G 96 1 O GLN G 94 N VAL G 4
SHEET 3 AB7 6 THR G 81 GLU G 85 -1 N TYR G 82 O VAL G 93
SHEET 4 AB7 6 HIS G 27 LYS G 29 -1 N LYS G 29 O ILE G 83
SHEET 5 AB7 6 LYS G 35 GLN G 40 -1 O ILE G 36 N TRP G 28
SHEET 6 AB7 6 PHE G 43 THR G 45 -1 O PHE G 43 N GLN G 40
SHEET 1 AB8 3 VAL G 12 THR G 17 0
SHEET 2 AB8 3 ASN G 66 ILE G 71 -1 O LEU G 69 N LEU G 14
SHEET 3 AB8 3 ALA G 55 ASP G 56 -1 N ASP G 56 O ILE G 70
SHEET 1 AB9 6 LYS H 2 LEU H 5 0
SHEET 2 AB9 6 GLU H 91 LEU H 96 1 O GLN H 94 N VAL H 4
SHEET 3 AB9 6 THR H 81 GLU H 85 -1 N TYR H 82 O VAL H 93
SHEET 4 AB9 6 HIS H 27 LYS H 29 -1 N LYS H 29 O ILE H 83
SHEET 5 AB9 6 LYS H 35 GLN H 40 -1 O ILE H 36 N TRP H 28
SHEET 6 AB9 6 PHE H 43 THR H 45 -1 O PHE H 43 N GLN H 40
SHEET 1 AC1 3 VAL H 12 THR H 17 0
SHEET 2 AC1 3 ASN H 66 ILE H 71 -1 O LEU H 69 N LEU H 14
SHEET 3 AC1 3 ALA H 55 ASP H 56 -1 N ASP H 56 O ILE H 70
SHEET 1 AC2 6 LYS I 2 LEU I 5 0
SHEET 2 AC2 6 GLU I 91 LEU I 96 1 O GLN I 94 N VAL I 4
SHEET 3 AC2 6 THR I 81 GLU I 85 -1 N TYR I 82 O VAL I 93
SHEET 4 AC2 6 HIS I 27 LYS I 29 -1 N LYS I 29 O ILE I 83
SHEET 5 AC2 6 LYS I 35 GLN I 40 -1 O ILE I 36 N TRP I 28
SHEET 6 AC2 6 PHE I 43 THR I 45 -1 O PHE I 43 N GLN I 40
SHEET 1 AC3 3 VAL I 12 THR I 17 0
SHEET 2 AC3 3 ASN I 66 ILE I 71 -1 O LEU I 69 N LEU I 14
SHEET 3 AC3 3 ALA I 55 ASP I 56 -1 N ASP I 56 O ILE I 70
SHEET 1 AC4 4 THR J 5 GLN J 6 0
SHEET 2 AC4 4 LEU J 21 ARG J 24 -1 O ARG J 24 N THR J 5
SHEET 3 AC4 4 GLU J 70 ILE J 75 -1 O PHE J 71 N CYS J 23
SHEET 4 AC4 4 PHE J 62 SER J 67 -1 N SER J 65 O THR J 72
SHEET 1 AC5 5 THR J 53 ARG J 54 0
SHEET 2 AC5 5 ARG J 45 TYR J 49 -1 N TYR J 49 O THR J 53
SHEET 3 AC5 5 LEU J 33 GLN J 38 -1 N TRP J 35 O LEU J 47
SHEET 4 AC5 5 VAL J 85 GLN J 90 -1 O VAL J 85 N GLN J 38
SHEET 5 AC5 5 THR J 104 ARG J 105 -1 O THR J 104 N TYR J 86
SHEET 1 AC6 2 GLN K 3 GLU K 6 0
SHEET 2 AC6 2 CYS K 22 SER K 25 -1 O SER K 25 N GLN K 3
SHEET 1 AC7 6 GLU K 10 LYS K 12 0
SHEET 2 AC7 6 THR K 122 VAL K 126 1 O THR K 125 N LYS K 12
SHEET 3 AC7 6 ALA K 92 TYR K 100 -1 N ALA K 92 O VAL K 124
SHEET 4 AC7 6 TYR K 32 GLN K 39 -1 N GLN K 39 O VAL K 93
SHEET 5 AC7 6 LEU K 45 ILE K 52 -1 O GLU K 46 N ARG K 38
SHEET 6 AC7 6 VAL K 57 TYR K 60 -1 O VAL K 57 N ILE K 52
SHEET 1 AC8 4 GLU K 10 LYS K 12 0
SHEET 2 AC8 4 THR K 122 VAL K 126 1 O THR K 125 N LYS K 12
SHEET 3 AC8 4 ALA K 92 TYR K 100 -1 N ALA K 92 O VAL K 124
SHEET 4 AC8 4 HIS K 117 TRP K 118 -1 O HIS K 117 N GLY K 98
SHEET 1 AC9 3 VAL K 18 VAL K 20 0
SHEET 2 AC9 3 THR K 78 LEU K 83 -1 O LEU K 83 N VAL K 18
SHEET 3 AC9 3 VAL K 68 ASP K 73 -1 N ASP K 73 O THR K 78
SHEET 1 AD1 4 THR L 5 GLN L 6 0
SHEET 2 AD1 4 LEU L 21 ARG L 24 -1 O ARG L 24 N THR L 5
SHEET 3 AD1 4 GLU L 70 ILE L 75 -1 O PHE L 71 N CYS L 23
SHEET 4 AD1 4 PHE L 62 SER L 67 -1 N SER L 65 O THR L 72
SHEET 1 AD2 5 THR L 53 ARG L 54 0
SHEET 2 AD2 5 ARG L 45 TYR L 49 -1 N TYR L 49 O THR L 53
SHEET 3 AD2 5 LEU L 33 GLN L 38 -1 N TRP L 35 O LEU L 47
SHEET 4 AD2 5 VAL L 85 GLN L 90 -1 O VAL L 85 N GLN L 38
SHEET 5 AD2 5 THR L 104 ARG L 105 -1 O THR L 104 N TYR L 86
SHEET 1 AD3 2 GLN M 3 GLU M 6 0
SHEET 2 AD3 2 CYS M 22 SER M 25 -1 O SER M 25 N GLN M 3
SHEET 1 AD4 6 GLU M 10 LYS M 12 0
SHEET 2 AD4 6 THR M 122 VAL M 126 1 O THR M 125 N LYS M 12
SHEET 3 AD4 6 ALA M 92 TYR M 100 -1 N ALA M 92 O VAL M 124
SHEET 4 AD4 6 TYR M 32 GLN M 39 -1 N GLN M 39 O VAL M 93
SHEET 5 AD4 6 LEU M 45 ILE M 52 -1 O GLU M 46 N ARG M 38
SHEET 6 AD4 6 VAL M 57 TYR M 60 -1 O VAL M 57 N ILE M 52
SHEET 1 AD5 4 GLU M 10 LYS M 12 0
SHEET 2 AD5 4 THR M 122 VAL M 126 1 O THR M 125 N LYS M 12
SHEET 3 AD5 4 ALA M 92 TYR M 100 -1 N ALA M 92 O VAL M 124
SHEET 4 AD5 4 HIS M 117 TRP M 118 -1 O HIS M 117 N GLY M 98
SHEET 1 AD6 3 VAL M 18 VAL M 20 0
SHEET 2 AD6 3 THR M 78 LEU M 83 -1 O LEU M 83 N VAL M 18
SHEET 3 AD6 3 VAL M 68 ASP M 73 -1 N ASP M 73 O THR M 78
SHEET 1 AD7 4 THR N 5 GLN N 6 0
SHEET 2 AD7 4 LEU N 21 ARG N 24 -1 O ARG N 24 N THR N 5
SHEET 3 AD7 4 GLU N 70 ILE N 75 -1 O PHE N 71 N CYS N 23
SHEET 4 AD7 4 PHE N 62 SER N 67 -1 N SER N 65 O THR N 72
SHEET 1 AD8 5 THR N 53 ARG N 54 0
SHEET 2 AD8 5 ARG N 45 TYR N 49 -1 N TYR N 49 O THR N 53
SHEET 3 AD8 5 LEU N 33 GLN N 38 -1 N TRP N 35 O LEU N 47
SHEET 4 AD8 5 VAL N 85 GLN N 90 -1 O VAL N 85 N GLN N 38
SHEET 5 AD8 5 THR N 104 ARG N 105 -1 O THR N 104 N TYR N 86
SHEET 1 AD9 2 GLN O 3 GLU O 6 0
SHEET 2 AD9 2 CYS O 22 SER O 25 -1 O SER O 25 N GLN O 3
SHEET 1 AE1 6 GLU O 10 LYS O 12 0
SHEET 2 AE1 6 THR O 122 VAL O 126 1 O THR O 125 N LYS O 12
SHEET 3 AE1 6 ALA O 92 TYR O 100 -1 N ALA O 92 O VAL O 124
SHEET 4 AE1 6 TYR O 32 GLN O 39 -1 N GLN O 39 O VAL O 93
SHEET 5 AE1 6 LEU O 45 ILE O 52 -1 O GLU O 46 N ARG O 38
SHEET 6 AE1 6 VAL O 57 TYR O 60 -1 O VAL O 57 N ILE O 52
SHEET 1 AE2 4 GLU O 10 LYS O 12 0
SHEET 2 AE2 4 THR O 122 VAL O 126 1 O THR O 125 N LYS O 12
SHEET 3 AE2 4 ALA O 92 TYR O 100 -1 N ALA O 92 O VAL O 124
SHEET 4 AE2 4 HIS O 117 TRP O 118 -1 O HIS O 117 N GLY O 98
SHEET 1 AE3 3 VAL O 18 VAL O 20 0
SHEET 2 AE3 3 THR O 78 LEU O 83 -1 O LEU O 83 N VAL O 18
SHEET 3 AE3 3 VAL O 68 ASP O 73 -1 N ASP O 73 O THR O 78
SHEET 1 AE4 4 VAL P 5 GLN P 6 0
SHEET 2 AE4 4 VAL P 18 LYS P 23 -1 O LYS P 23 N VAL P 5
SHEET 3 AE4 4 ILE P 81 ILE P 86 -1 O SER P 82 N CYS P 22
SHEET 4 AE4 4 VAL P 67 VAL P 72 -1 N LEU P 68 O GLU P 85
SHEET 1 AE5 6 GLU P 10 LYS P 12 0
SHEET 2 AE5 6 THR P 126 VAL P 130 1 O LEU P 127 N GLU P 10
SHEET 3 AE5 6 ALA P 95 SER P 103 -1 N ALA P 95 O ILE P 128
SHEET 4 AE5 6 TYR P 33 GLN P 40 -1 N GLN P 40 O VAL P 96
SHEET 5 AE5 6 LEU P 46 GLN P 51 -1 O GLU P 47 N ARG P 39
SHEET 6 AE5 6 SER P 58 ALA P 59 -1 O SER P 58 N GLN P 51
SHEET 1 AE6 4 GLU P 10 LYS P 12 0
SHEET 2 AE6 4 THR P 126 VAL P 130 1 O LEU P 127 N GLU P 10
SHEET 3 AE6 4 ALA P 95 SER P 103 -1 N ALA P 95 O ILE P 128
SHEET 4 AE6 4 SER P 121 TRP P 122 -1 O SER P 121 N THR P 101
SHEET 1 AE7 2 HIS P 112 HIS P 113 0
SHEET 2 AE7 2 VAL P 116 MET P 117 -1 O VAL P 116 N HIS P 113
SHEET 1 AE8 4 MET Q 4 SER Q 7 0
SHEET 2 AE8 4 VAL Q 19 ALA Q 25 -1 O ARG Q 24 N THR Q 5
SHEET 3 AE8 4 ASP Q 71 ILE Q 76 -1 O LEU Q 74 N ILE Q 21
SHEET 4 AE8 4 PHE Q 63 ALA Q 67 -1 N SER Q 64 O THR Q 75
SHEET 1 AE9 5 ALA Q 54 LEU Q 55 0
SHEET 2 AE9 5 ARG Q 46 TYR Q 50 -1 N TYR Q 50 O ALA Q 54
SHEET 3 AE9 5 VAL Q 34 GLN Q 39 -1 N TRP Q 36 O LEU Q 48
SHEET 4 AE9 5 THR Q 86 GLN Q 91 -1 O THR Q 86 N GLN Q 39
SHEET 5 AE9 5 THR Q 98 PHE Q 99 -1 O THR Q 98 N GLN Q 91
SHEET 1 AF1 5 ALA Q 54 LEU Q 55 0
SHEET 2 AF1 5 ARG Q 46 TYR Q 50 -1 N TYR Q 50 O ALA Q 54
SHEET 3 AF1 5 VAL Q 34 GLN Q 39 -1 N TRP Q 36 O LEU Q 48
SHEET 4 AF1 5 THR Q 86 GLN Q 91 -1 O THR Q 86 N GLN Q 39
SHEET 5 AF1 5 THR Q 103 LYS Q 104 -1 O THR Q 103 N PHE Q 87
SHEET 1 AF2 4 VAL R 5 GLN R 6 0
SHEET 2 AF2 4 VAL R 18 LYS R 23 -1 O LYS R 23 N VAL R 5
SHEET 3 AF2 4 ILE R 81 ILE R 86 -1 O SER R 82 N CYS R 22
SHEET 4 AF2 4 VAL R 67 VAL R 72 -1 N LEU R 68 O GLU R 85
SHEET 1 AF3 6 GLU R 10 LYS R 12 0
SHEET 2 AF3 6 THR R 126 VAL R 130 1 O LEU R 127 N GLU R 10
SHEET 3 AF3 6 ALA R 95 SER R 103 -1 N ALA R 95 O ILE R 128
SHEET 4 AF3 6 TYR R 33 GLN R 40 -1 N GLN R 40 O VAL R 96
SHEET 5 AF3 6 LEU R 46 GLN R 51 -1 O GLU R 47 N ARG R 39
SHEET 6 AF3 6 SER R 58 ALA R 59 -1 O SER R 58 N GLN R 51
SHEET 1 AF4 4 GLU R 10 LYS R 12 0
SHEET 2 AF4 4 THR R 126 VAL R 130 1 O LEU R 127 N GLU R 10
SHEET 3 AF4 4 ALA R 95 SER R 103 -1 N ALA R 95 O ILE R 128
SHEET 4 AF4 4 SER R 121 TRP R 122 -1 O SER R 121 N THR R 101
SHEET 1 AF5 2 HIS R 112 HIS R 113 0
SHEET 2 AF5 2 VAL R 116 MET R 117 -1 O VAL R 116 N HIS R 113
SHEET 1 AF6 4 MET S 4 SER S 7 0
SHEET 2 AF6 4 VAL S 19 ALA S 25 -1 O ARG S 24 N THR S 5
SHEET 3 AF6 4 ASP S 71 ILE S 76 -1 O LEU S 74 N ILE S 21
SHEET 4 AF6 4 PHE S 63 ALA S 67 -1 N SER S 64 O THR S 75
SHEET 1 AF7 5 ALA S 54 LEU S 55 0
SHEET 2 AF7 5 ARG S 46 TYR S 50 -1 N TYR S 50 O ALA S 54
SHEET 3 AF7 5 VAL S 34 GLN S 39 -1 N TRP S 36 O LEU S 48
SHEET 4 AF7 5 THR S 86 GLN S 91 -1 O THR S 86 N GLN S 39
SHEET 5 AF7 5 THR S 98 PHE S 99 -1 O THR S 98 N GLN S 91
SHEET 1 AF8 5 ALA S 54 LEU S 55 0
SHEET 2 AF8 5 ARG S 46 TYR S 50 -1 N TYR S 50 O ALA S 54
SHEET 3 AF8 5 VAL S 34 GLN S 39 -1 N TRP S 36 O LEU S 48
SHEET 4 AF8 5 THR S 86 GLN S 91 -1 O THR S 86 N GLN S 39
SHEET 5 AF8 5 THR S 103 LYS S 104 -1 O THR S 103 N PHE S 87
SHEET 1 AF9 4 VAL T 5 GLN T 6 0
SHEET 2 AF9 4 VAL T 18 LYS T 23 -1 O LYS T 23 N VAL T 5
SHEET 3 AF9 4 ILE T 81 ILE T 86 -1 O SER T 82 N CYS T 22
SHEET 4 AF9 4 VAL T 67 VAL T 72 -1 N LEU T 68 O GLU T 85
SHEET 1 AG1 6 GLU T 10 LYS T 12 0
SHEET 2 AG1 6 THR T 126 VAL T 130 1 O LEU T 127 N GLU T 10
SHEET 3 AG1 6 ALA T 95 SER T 103 -1 N ALA T 95 O ILE T 128
SHEET 4 AG1 6 TYR T 33 GLN T 40 -1 N GLN T 40 O VAL T 96
SHEET 5 AG1 6 LEU T 46 GLN T 51 -1 O GLU T 47 N ARG T 39
SHEET 6 AG1 6 SER T 58 ALA T 59 -1 O SER T 58 N GLN T 51
SHEET 1 AG2 4 GLU T 10 LYS T 12 0
SHEET 2 AG2 4 THR T 126 VAL T 130 1 O LEU T 127 N GLU T 10
SHEET 3 AG2 4 ALA T 95 SER T 103 -1 N ALA T 95 O ILE T 128
SHEET 4 AG2 4 SER T 121 TRP T 122 -1 O SER T 121 N THR T 101
SHEET 1 AG3 2 HIS T 112 HIS T 113 0
SHEET 2 AG3 2 VAL T 116 MET T 117 -1 O VAL T 116 N HIS T 113
SHEET 1 AG4 4 MET U 4 SER U 7 0
SHEET 2 AG4 4 VAL U 19 ALA U 25 -1 O ARG U 24 N THR U 5
SHEET 3 AG4 4 ASP U 71 ILE U 76 -1 O LEU U 74 N ILE U 21
SHEET 4 AG4 4 PHE U 63 ALA U 67 -1 N SER U 64 O THR U 75
SHEET 1 AG5 5 ALA U 54 LEU U 55 0
SHEET 2 AG5 5 ARG U 46 TYR U 50 -1 N TYR U 50 O ALA U 54
SHEET 3 AG5 5 VAL U 34 GLN U 39 -1 N TRP U 36 O LEU U 48
SHEET 4 AG5 5 THR U 86 GLN U 91 -1 O THR U 86 N GLN U 39
SHEET 5 AG5 5 THR U 98 PHE U 99 -1 O THR U 98 N GLN U 91
SHEET 1 AG6 5 ALA U 54 LEU U 55 0
SHEET 2 AG6 5 ARG U 46 TYR U 50 -1 N TYR U 50 O ALA U 54
SHEET 3 AG6 5 VAL U 34 GLN U 39 -1 N TRP U 36 O LEU U 48
SHEET 4 AG6 5 THR U 86 GLN U 91 -1 O THR U 86 N GLN U 39
SHEET 5 AG6 5 THR U 103 LYS U 104 -1 O THR U 103 N PHE U 87
SSBOND 1 CYS A 598 CYS A 604 1555 1555 2.02
SSBOND 2 CYS A 605 CYS E 501 1555 1555 1.97
SSBOND 3 CYS B 598 CYS B 604 1555 1555 2.02
SSBOND 4 CYS B 605 CYS D 501 1555 1555 2.02
SSBOND 5 CYS C 598 CYS C 604 1555 1555 2.02
SSBOND 6 CYS C 605 CYS F 501 1555 1555 2.10
SSBOND 7 CYS D 54 CYS D 74 1555 1555 2.04
SSBOND 8 CYS D 119 CYS D 205 1555 1555 2.03
SSBOND 9 CYS D 126 CYS D 196 1555 1555 2.03
SSBOND 10 CYS D 218 CYS D 247 1555 1555 2.03
SSBOND 11 CYS D 228 CYS D 239 1555 1555 2.03
SSBOND 12 CYS D 296 CYS D 331 1555 1555 2.03
SSBOND 13 CYS D 378 CYS D 445 1555 1555 2.02
SSBOND 14 CYS D 385 CYS D 418 1555 1555 2.05
SSBOND 15 CYS E 54 CYS E 74 1555 1555 2.04
SSBOND 16 CYS E 119 CYS E 205 1555 1555 2.03
SSBOND 17 CYS E 126 CYS E 196 1555 1555 2.03
SSBOND 18 CYS E 218 CYS E 247 1555 1555 2.03
SSBOND 19 CYS E 228 CYS E 239 1555 1555 2.03
SSBOND 20 CYS E 296 CYS E 331 1555 1555 2.03
SSBOND 21 CYS E 378 CYS E 445 1555 1555 2.02
SSBOND 22 CYS E 385 CYS E 418 1555 1555 2.05
SSBOND 23 CYS F 54 CYS F 74 1555 1555 2.04
SSBOND 24 CYS F 119 CYS F 205 1555 1555 2.03
SSBOND 25 CYS F 126 CYS F 196 1555 1555 2.03
SSBOND 26 CYS F 218 CYS F 247 1555 1555 2.03
SSBOND 27 CYS F 228 CYS F 239 1555 1555 2.03
SSBOND 28 CYS F 296 CYS F 331 1555 1555 2.03
SSBOND 29 CYS F 378 CYS F 445 1555 1555 2.02
SSBOND 30 CYS F 385 CYS F 418 1555 1555 2.05
SSBOND 31 CYS G 16 CYS G 84 1555 1555 2.02
SSBOND 32 CYS H 16 CYS H 84 1555 1555 2.02
SSBOND 33 CYS I 16 CYS I 84 1555 1555 2.02
SSBOND 34 CYS J 23 CYS J 88 1555 1555 2.04
SSBOND 35 CYS K 22 CYS K 96 1555 1555 2.03
SSBOND 36 CYS L 23 CYS L 88 1555 1555 2.04
SSBOND 37 CYS M 22 CYS M 96 1555 1555 2.03
SSBOND 38 CYS N 23 CYS N 88 1555 1555 2.04
SSBOND 39 CYS O 22 CYS O 96 1555 1555 2.03
SSBOND 40 CYS P 22 CYS P 99 1555 1555 2.02
SSBOND 41 CYS Q 23 CYS Q 89 1555 1555 2.04
SSBOND 42 CYS R 22 CYS R 99 1555 1555 2.02
SSBOND 43 CYS S 23 CYS S 89 1555 1555 2.04
SSBOND 44 CYS T 22 CYS T 99 1555 1555 2.02
SSBOND 45 CYS U 23 CYS U 89 1555 1555 2.04
LINK ND2 ASN A 637 C1 NAG V 1 1555 1555 1.44
LINK ND2 ASN B 637 C1 NAG W 1 1555 1555 1.45
LINK ND2 ASN C 637 C1 NAG X 1 1555 1555 1.45
LINK ND2 ASN D 234 C1 NAG Y 1 1555 1555 1.43
LINK ND2 ASN D 262 C1 NAG Z 1 1555 1555 1.43
LINK ND2 ASN D 276 C1 NAG a 1 1555 1555 1.44
LINK ND2 ASN D 295 C1 NAG D 621 1555 1555 1.43
LINK ND2 ASN D 332 C1 NAG D 622 1555 1555 1.43
LINK ND2 ASN D 339 C1 NAG D 623 1555 1555 1.43
LINK ND2 ASN D 363 C1 NAG D 624 1555 1555 1.44
LINK ND2 ASN D 386 C1 NAG b 1 1555 1555 1.44
LINK ND2 ASN D 392 C1 NAG D 627 1555 1555 1.44
LINK OE1 GLN D 440 C4 MAN Z 5 1555 1555 1.38
LINK ND2 ASN D 448 C1 NAG D 628 1555 1555 1.43
LINK ND2 ASN E 234 C1 NAG c 1 1555 1555 1.43
LINK ND2 ASN E 262 C1 NAG d 1 1555 1555 1.43
LINK ND2 ASN E 276 C1 NAG e 1 1555 1555 1.43
LINK ND2 ASN E 295 C1 NAG E 621 1555 1555 1.43
LINK ND2 ASN E 332 C1 NAG E 622 1555 1555 1.43
LINK ND2 ASN E 339 C1 NAG E 623 1555 1555 1.43
LINK ND2 ASN E 363 C1 NAG E 624 1555 1555 1.44
LINK ND2 ASN E 386 C1 NAG f 1 1555 1555 1.44
LINK ND2 ASN E 392 C1 NAG E 627 1555 1555 1.44
LINK OE1 GLN E 440 C4 MAN d 5 1555 1555 1.38
LINK ND2 ASN E 448 C1 NAG E 628 1555 1555 1.43
LINK ND2 ASN F 234 C1 NAG g 1 1555 1555 1.43
LINK ND2 ASN F 262 C1 NAG h 1 1555 1555 1.43
LINK ND2 ASN F 276 C1 NAG i 1 1555 1555 1.44
LINK ND2 ASN F 295 C1 NAG F 621 1555 1555 1.43
LINK ND2 ASN F 332 C1 NAG F 622 1555 1555 1.43
LINK ND2 ASN F 339 C1 NAG F 623 1555 1555 1.44
LINK ND2 ASN F 363 C1 NAG F 624 1555 1555 1.44
LINK ND2 ASN F 386 C1 NAG j 1 1555 1555 1.44
LINK ND2 ASN F 392 C1 NAG F 627 1555 1555 1.44
LINK OE1 GLN F 440 C4 MAN h 5 1555 1555 1.38
LINK ND2 ASN F 448 C1 NAG F 628 1555 1555 1.42
LINK O4 NAG V 1 C1 NAG V 2 1555 1555 1.43
LINK O4 NAG W 1 C1 NAG W 2 1555 1555 1.44
LINK O4 NAG X 1 C1 NAG X 2 1555 1555 1.44
LINK O4 NAG Y 1 C1 NAG Y 2 1555 1555 1.43
LINK O4 NAG Y 2 C1 BMA Y 3 1555 1555 1.43
LINK O3 BMA Y 3 C1 MAN Y 4 1555 1555 1.44
LINK O6 BMA Y 3 C1 MAN Y 7 1555 1555 1.42
LINK O2 MAN Y 4 C1 MAN Y 5 1555 1555 1.44
LINK O2 MAN Y 5 C1 MAN Y 6 1555 1555 1.44
LINK O6 MAN Y 7 C1 MAN Y 8 1555 1555 1.43
LINK O3 MAN Y 7 C1 MAN Y 10 1555 1555 1.44
LINK O2 MAN Y 8 C1 MAN Y 9 1555 1555 1.44
LINK O4 NAG Z 1 C1 NAG Z 2 1555 1555 1.44
LINK O4 NAG Z 2 C1 BMA Z 3 1555 1555 1.44
LINK O3 BMA Z 3 C1 MAN Z 4 1555 1555 1.43
LINK O2 MAN Z 4 C1 MAN Z 5 1555 1555 1.43
LINK O4 NAG a 1 C1 NAG a 2 1555 1555 1.44
LINK O4 NAG a 2 C1 BMA a 3 1555 1555 1.44
LINK O3 BMA a 3 C1 MAN a 4 1555 1555 1.43
LINK O6 BMA a 3 C1 MAN a 5 1555 1555 1.44
LINK O4 NAG b 1 C1 NAG b 2 1555 1555 1.46
LINK O4 NAG c 1 C1 NAG c 2 1555 1555 1.43
LINK O4 NAG c 2 C1 BMA c 3 1555 1555 1.43
LINK O3 BMA c 3 C1 MAN c 4 1555 1555 1.44
LINK O6 BMA c 3 C1 MAN c 7 1555 1555 1.43
LINK O2 MAN c 4 C1 MAN c 5 1555 1555 1.44
LINK O2 MAN c 5 C1 MAN c 6 1555 1555 1.44
LINK O6 MAN c 7 C1 MAN c 8 1555 1555 1.43
LINK O3 MAN c 7 C1 MAN c 10 1555 1555 1.44
LINK O2 MAN c 8 C1 MAN c 9 1555 1555 1.44
LINK O4 NAG d 1 C1 NAG d 2 1555 1555 1.44
LINK O4 NAG d 2 C1 BMA d 3 1555 1555 1.44
LINK O3 BMA d 3 C1 MAN d 4 1555 1555 1.43
LINK O2 MAN d 4 C1 MAN d 5 1555 1555 1.43
LINK O4 NAG e 1 C1 NAG e 2 1555 1555 1.44
LINK O4 NAG e 2 C1 BMA e 3 1555 1555 1.44
LINK O3 BMA e 3 C1 MAN e 4 1555 1555 1.43
LINK O6 BMA e 3 C1 MAN e 5 1555 1555 1.44
LINK O4 NAG f 1 C1 NAG f 2 1555 1555 1.46
LINK O4 NAG g 1 C1 NAG g 2 1555 1555 1.43
LINK O4 NAG g 2 C1 BMA g 3 1555 1555 1.43
LINK O3 BMA g 3 C1 MAN g 4 1555 1555 1.44
LINK O6 BMA g 3 C1 MAN g 7 1555 1555 1.43
LINK O2 MAN g 4 C1 MAN g 5 1555 1555 1.44
LINK O2 MAN g 5 C1 MAN g 6 1555 1555 1.44
LINK O6 MAN g 7 C1 MAN g 8 1555 1555 1.43
LINK O3 MAN g 7 C1 MAN g 10 1555 1555 1.44
LINK O2 MAN g 8 C1 MAN g 9 1555 1555 1.44
LINK O4 NAG h 1 C1 NAG h 2 1555 1555 1.44
LINK O4 NAG h 2 C1 BMA h 3 1555 1555 1.44
LINK O3 BMA h 3 C1 MAN h 4 1555 1555 1.43
LINK O2 MAN h 4 C1 MAN h 5 1555 1555 1.43
LINK O4 NAG i 1 C1 NAG i 2 1555 1555 1.44
LINK O4 NAG i 2 C1 BMA i 3 1555 1555 1.44
LINK O3 BMA i 3 C1 MAN i 4 1555 1555 1.43
LINK O6 BMA i 3 C1 MAN i 5 1555 1555 1.44
LINK O4 NAG j 1 C1 NAG j 2 1555 1555 1.46
CISPEP 1 CYS D 54 ALA D 55 0 -2.70
CISPEP 2 LYS D 189 GLU D 190 0 -2.48
CISPEP 3 GLU D 190 TYR D 191 0 -9.32
CISPEP 4 ILE D 323 GLY D 324 0 -3.30
CISPEP 5 ILE D 359 ARG D 360 0 0.92
CISPEP 6 GLY D 459 SER D 460 0 -0.89
CISPEP 7 SER D 463 THR D 464 0 11.32
CISPEP 8 CYS E 54 ALA E 55 0 -2.71
CISPEP 9 LYS E 189 GLU E 190 0 -2.42
CISPEP 10 GLU E 190 TYR E 191 0 -9.34
CISPEP 11 ILE E 323 GLY E 324 0 -3.30
CISPEP 12 ILE E 359 ARG E 360 0 0.89
CISPEP 13 GLY E 459 SER E 460 0 -0.97
CISPEP 14 SER E 463 THR E 464 0 11.34
CISPEP 15 CYS F 54 ALA F 55 0 -2.62
CISPEP 16 LYS F 189 GLU F 190 0 -2.51
CISPEP 17 GLU F 190 TYR F 191 0 -9.28
CISPEP 18 ILE F 323 GLY F 324 0 -3.39
CISPEP 19 ILE F 359 ARG F 360 0 0.87
CISPEP 20 GLY F 459 SER F 460 0 -0.97
CISPEP 21 SER F 463 THR F 464 0 11.24
CISPEP 22 TRP J 94 PRO J 95 0 -2.86
CISPEP 23 TRP L 94 PRO L 95 0 -2.98
CISPEP 24 TRP N 94 PRO N 95 0 -2.90
CISPEP 25 SER Q 7 PRO Q 8 0 -6.61
CISPEP 26 TYR Q 95 PRO Q 96 0 -5.49
CISPEP 27 SER S 7 PRO S 8 0 -6.65
CISPEP 28 TYR S 95 PRO S 96 0 -5.50
CISPEP 29 SER U 7 PRO U 8 0 -6.67
CISPEP 30 TYR U 95 PRO U 96 0 -5.37
CRYST1 1.000 1.000 1.000 90.00 90.00 90.00 P 1 1
ORIGX1 1.000000 0.000000 0.000000 0.00000
ORIGX2 0.000000 1.000000 0.000000 0.00000
ORIGX3 0.000000 0.000000 1.000000 0.00000
SCALE1 1.000000 0.000000 0.000000 0.00000
SCALE2 0.000000 1.000000 0.000000 0.00000
SCALE3 0.000000 0.000000 1.000000 0.00000
(ATOM LINES ARE NOT SHOWN.)
END
