HEADER MEMBRANE PROTEIN 20-JUN-18 6DU8
TITLE HUMAN POLYCSYTIN 2-L1
COMPND MOL_ID: 1;
COMPND 2 MOLECULE: POLYCYSTIC KIDNEY DISEASE 2-LIKE 1 PROTEIN;
COMPND 3 CHAIN: A, B, C, D;
COMPND 4 SYNONYM: POLYCYSTIN-2 HOMOLOG,POLYCYSTIN-2L1,POLYCYSTIN-L,POLYCYSTIN-
COMPND 5 L1;
COMPND 6 ENGINEERED: YES
SOURCE MOL_ID: 1;
SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS;
SOURCE 3 ORGANISM_COMMON: HUMAN;
SOURCE 4 ORGANISM_TAXID: 9606;
SOURCE 5 GENE: PKD2L1, PKD2L, PKDL, TRPP3;
SOURCE 6 EXPRESSION_SYSTEM: HOMO SAPIENS;
SOURCE 7 EXPRESSION_SYSTEM_COMMON: HUMAN;
SOURCE 8 EXPRESSION_SYSTEM_TAXID: 9606;
SOURCE 9 EXPRESSION_SYSTEM_CELL_LINE: HEK293S;
SOURCE 10 EXPRESSION_SYSTEM_ATCC_NUMBER: CRL-3022;
SOURCE 11 EXPRESSION_SYSTEM_CELL: HEK-293S GNTL;
SOURCE 12 EXPRESSION_SYSTEM_PLASMID: PEG
KEYWDS POLYCYSTIC 2-L1, PC2L1, PKD2L1, TRPP2, MEMBRANE PROTEIN
EXPDTA ELECTRON MICROSCOPY
AUTHOR R.E.HULSE,D.E.CLAPHAM,Z.LI,R.K.HUANG,J.ZHANG
REVDAT 4 29-JUL-20 6DU8 1 COMPND REMARK HETNAM LINK
REVDAT 4 2 1 SITE
REVDAT 3 18-DEC-19 6DU8 1 CRYST1 SCALE
REVDAT 2 20-NOV-19 6DU8 1 REMARK
REVDAT 1 25-JUL-18 6DU8 0
JRNL AUTH R.E.HULSE,Z.LI,R.K.HUANG,J.ZHANG,D.E.CLAPHAM
JRNL TITL CRYO-EM STRUCTURE OF THE POLYCYSTIN 2-L1 ION CHANNEL.
JRNL REF ELIFE V. 7 2018
JRNL REFN ESSN 2050-084X
JRNL PMID 30004384
JRNL DOI 10.7554/ELIFE.36931
REMARK 2
REMARK 2 RESOLUTION. 3.11 ANGSTROMS.
REMARK 3
REMARK 3 REFINEMENT.
REMARK 3 SOFTWARE PACKAGES : NULL
REMARK 3 RECONSTRUCTION SCHEMA : NULL
REMARK 3
REMARK 3 EM MAP-MODEL FITTING AND REFINEMENT
REMARK 3 PDB ENTRY : NULL
REMARK 3 REFINEMENT SPACE : NULL
REMARK 3 REFINEMENT PROTOCOL : NULL
REMARK 3 REFINEMENT TARGET : NULL
REMARK 3 OVERALL ANISOTROPIC B VALUE : NULL
REMARK 3
REMARK 3 FITTING PROCEDURE : NULL
REMARK 3
REMARK 3 EM IMAGE RECONSTRUCTION STATISTICS
REMARK 3 NOMINAL PIXEL SIZE (ANGSTROMS) : NULL
REMARK 3 ACTUAL PIXEL SIZE (ANGSTROMS) : NULL
REMARK 3 EFFECTIVE RESOLUTION (ANGSTROMS) : 3.110
REMARK 3 NUMBER OF PARTICLES : 119334
REMARK 3 CTF CORRECTION METHOD : PHASE FLIPPING AND AMPLITUDE
REMARK 3 CORRECTION
REMARK 3
REMARK 3 EM RECONSTRUCTION MAGNIFICATION CALIBRATION: NULL
REMARK 3
REMARK 3 OTHER DETAILS: NULL
REMARK 4
REMARK 4 6DU8 COMPLIES WITH FORMAT V. 3.30, 13-JUL-11
REMARK 100
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 21-JUN-18.
REMARK 100 THE DEPOSITION ID IS D_1000233422.
REMARK 245
REMARK 245 EXPERIMENTAL DETAILS
REMARK 245 RECONSTRUCTION METHOD : SINGLE PARTICLE
REMARK 245 SPECIMEN TYPE : NULL
REMARK 245
REMARK 245 ELECTRON MICROSCOPE SAMPLE
REMARK 245 SAMPLE TYPE : 3D ARRAY
REMARK 245 PARTICLE TYPE : POINT
REMARK 245 NAME OF SAMPLE : HUMAN POLYCYSTIC 2-L
REMARK 245 SAMPLE CONCENTRATION (MG ML-1) : 3.50
REMARK 245 SAMPLE SUPPORT DETAILS : NULL
REMARK 245 SAMPLE VITRIFICATION DETAILS : NULL
REMARK 245 SAMPLE BUFFER : NULL
REMARK 245 PH : 7.50
REMARK 245 SAMPLE DETAILS : HOMOTETRAMERIC ASSEMBLY OF
REMARK 245 POLYCYSTIC 2-L1
REMARK 245
REMARK 245 DATA ACQUISITION
REMARK 245 DATE OF EXPERIMENT : NULL
REMARK 245 NUMBER OF MICROGRAPHS-IMAGES : NULL
REMARK 245 TEMPERATURE (KELVIN) : NULL
REMARK 245 MICROSCOPE MODEL : FEI TITAN KRIOS
REMARK 245 DETECTOR TYPE : GATAN K2 SUMMIT (4K X 4K)
REMARK 245 MINIMUM DEFOCUS (NM) : NULL
REMARK 245 MAXIMUM DEFOCUS (NM) : NULL
REMARK 245 MINIMUM TILT ANGLE (DEGREES) : NULL
REMARK 245 MAXIMUM TILT ANGLE (DEGREES) : NULL
REMARK 245 NOMINAL CS : NULL
REMARK 245 IMAGING MODE : OTHER
REMARK 245 ELECTRON DOSE (ELECTRONS NM**-2) : 60.00
REMARK 245 ILLUMINATION MODE : OTHER
REMARK 245 NOMINAL MAGNIFICATION : NULL
REMARK 245 CALIBRATED MAGNIFICATION : NULL
REMARK 245 SOURCE : FIELD EMISSION GUN
REMARK 245 ACCELERATION VOLTAGE (KV) : 300
REMARK 245 IMAGING DETAILS : NULL
REMARK 247
REMARK 247 ELECTRON MICROSCOPY
REMARK 247 THE COORDINATES IN THIS ENTRY WERE GENERATED FROM ELECTRON
REMARK 247 MICROSCOPY DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE
REMARK 247 THAT CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES
REMARK 247 ON THESE RECORDS ARE MEANINGLESS EXCEPT FOR THE CALCULATION
REMARK 247 OF THE STRUCTURE FACTORS.
REMARK 300
REMARK 300 BIOMOLECULE: 1
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON
REMARK 300 BURIED SURFACE AREA.
REMARK 350
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS
REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.
REMARK 350
REMARK 350 BIOMOLECULE: 1
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TETRAMERIC
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B, C, D
REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000
REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000
REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000
REMARK 465
REMARK 465 MISSING RESIDUES
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)
REMARK 465
REMARK 465 M RES C SSSEQI
REMARK 465 MET A 1
REMARK 465 ASN A 2
REMARK 465 ALA A 3
REMARK 465 VAL A 4
REMARK 465 GLY A 5
REMARK 465 SER A 6
REMARK 465 PRO A 7
REMARK 465 GLU A 8
REMARK 465 GLY A 9
REMARK 465 GLN A 10
REMARK 465 GLU A 11
REMARK 465 LEU A 12
REMARK 465 GLN A 13
REMARK 465 LYS A 14
REMARK 465 LEU A 15
REMARK 465 GLY A 16
REMARK 465 SER A 17
REMARK 465 GLY A 18
REMARK 465 ALA A 19
REMARK 465 TRP A 20
REMARK 465 ASP A 21
REMARK 465 ASN A 22
REMARK 465 PRO A 23
REMARK 465 ALA A 24
REMARK 465 TYR A 25
REMARK 465 SER A 26
REMARK 465 GLY A 27
REMARK 465 PRO A 28
REMARK 465 PRO A 29
REMARK 465 SER A 30
REMARK 465 PRO A 31
REMARK 465 HIS A 32
REMARK 465 GLY A 33
REMARK 465 THR A 34
REMARK 465 LEU A 35
REMARK 465 ARG A 36
REMARK 465 VAL A 37
REMARK 465 CYS A 38
REMARK 465 THR A 39
REMARK 465 ILE A 40
REMARK 465 SER A 41
REMARK 465 SER A 42
REMARK 465 THR A 43
REMARK 465 GLY A 44
REMARK 465 PRO A 45
REMARK 465 LEU A 46
REMARK 465 GLN A 47
REMARK 465 PRO A 48
REMARK 465 GLN A 49
REMARK 465 PRO A 50
REMARK 465 LYS A 51
REMARK 465 LYS A 52
REMARK 465 PRO A 53
REMARK 465 GLU A 54
REMARK 465 ASP A 55
REMARK 465 GLU A 56
REMARK 465 PRO A 57
REMARK 465 GLN A 58
REMARK 465 GLU A 59
REMARK 465 THR A 60
REMARK 465 ALA A 61
REMARK 465 TYR A 62
REMARK 465 ARG A 63
REMARK 465 THR A 64
REMARK 465 GLN A 65
REMARK 465 VAL A 66
REMARK 465 SER A 67
REMARK 465 SER A 68
REMARK 465 CYS A 69
REMARK 465 CYS A 70
REMARK 465 LEU A 71
REMARK 465 HIS A 72
REMARK 465 ILE A 73
REMARK 465 CYS A 74
REMARK 465 GLN A 75
REMARK 465 GLY A 76
REMARK 465 ILE A 77
REMARK 465 ARG A 78
REMARK 465 GLY A 79
REMARK 465 LEU A 80
REMARK 465 TRP A 81
REMARK 465 GLY A 82
REMARK 465 THR A 83
REMARK 465 THR A 84
REMARK 465 LEU A 85
REMARK 465 THR A 86
REMARK 465 GLU A 87
REMARK 465 ASN A 88
REMARK 465 THR A 89
REMARK 465 ALA A 90
REMARK 465 GLU A 91
REMARK 465 ASN A 92
REMARK 465 ARG A 93
REMARK 465 GLU A 94
REMARK 465 LEU A 95
REMARK 465 TYR A 96
REMARK 465 ILE A 97
REMARK 465 LYS A 98
REMARK 465 THR A 99
REMARK 465 THR A 100
REMARK 465 LYS A 173
REMARK 465 TRP A 174
REMARK 465 TYR A 175
REMARK 465 ASN A 176
REMARK 465 ASN A 177
REMARK 465 GLN A 178
REMARK 465 SER A 179
REMARK 465 LEU A 180
REMARK 465 TYR A 344
REMARK 465 VAL A 345
REMARK 465 SER A 346
REMARK 465 ASN A 347
REMARK 465 TRP A 348
REMARK 465 ASP A 349
REMARK 465 PHE A 350
REMARK 465 LEU A 382
REMARK 465 SER A 383
REMARK 465 ILE A 457
REMARK 465 SER A 458
REMARK 465 PHE A 459
REMARK 465 ASN A 460
REMARK 465 LYS A 461
REMARK 465 THR A 462
REMARK 465 MET A 463
REMARK 465 THR A 464
REMARK 465 GLN A 465
REMARK 465 LEU A 466
REMARK 465 SER A 467
REMARK 465 SER A 468
REMARK 465 THR A 469
REMARK 465 LEU A 470
REMARK 465 ALA A 471
REMARK 465 ARG A 472
REMARK 465 CYS A 473
REMARK 465 ALA A 474
REMARK 465 LYS A 475
REMARK 465 ASP A 476
REMARK 465 ILE A 477
REMARK 465 LEU A 478
REMARK 465 GLY A 479
REMARK 465 ASP A 562
REMARK 465 THR A 563
REMARK 465 TYR A 564
REMARK 465 SER A 565
REMARK 465 GLU A 566
REMARK 465 VAL A 567
REMARK 465 LYS A 568
REMARK 465 GLU A 569
REMARK 465 GLU A 570
REMARK 465 LEU A 571
REMARK 465 ALA A 572
REMARK 465 GLY A 573
REMARK 465 GLN A 574
REMARK 465 LYS A 575
REMARK 465 ASP A 576
REMARK 465 GLU A 577
REMARK 465 LEU A 578
REMARK 465 GLN A 579
REMARK 465 LEU A 580
REMARK 465 SER A 581
REMARK 465 ASP A 582
REMARK 465 LEU A 583
REMARK 465 LEU A 584
REMARK 465 LYS A 585
REMARK 465 GLN A 586
REMARK 465 GLY A 587
REMARK 465 TYR A 588
REMARK 465 ASN A 589
REMARK 465 LYS A 590
REMARK 465 THR A 591
REMARK 465 LEU A 592
REMARK 465 LEU A 593
REMARK 465 ARG A 594
REMARK 465 LEU A 595
REMARK 465 ARG A 596
REMARK 465 LEU A 597
REMARK 465 ARG A 598
REMARK 465 LYS A 599
REMARK 465 GLU A 600
REMARK 465 ARG A 601
REMARK 465 VAL A 602
REMARK 465 SER A 603
REMARK 465 ASP A 604
REMARK 465 VAL A 605
REMARK 465 GLN A 606
REMARK 465 LYS A 607
REMARK 465 VAL A 608
REMARK 465 LEU A 609
REMARK 465 GLN A 610
REMARK 465 GLY A 611
REMARK 465 GLY A 612
REMARK 465 GLU A 613
REMARK 465 GLN A 614
REMARK 465 GLU A 615
REMARK 465 ILE A 616
REMARK 465 GLN A 617
REMARK 465 PHE A 618
REMARK 465 GLU A 619
REMARK 465 ASP A 620
REMARK 465 PHE A 621
REMARK 465 THR A 622
REMARK 465 ASN A 623
REMARK 465 THR A 624
REMARK 465 LEU A 625
REMARK 465 ARG A 626
REMARK 465 GLU A 627
REMARK 465 LEU A 628
REMARK 465 GLY A 629
REMARK 465 HIS A 630
REMARK 465 ALA A 631
REMARK 465 GLU A 632
REMARK 465 HIS A 633
REMARK 465 GLU A 634
REMARK 465 ILE A 635
REMARK 465 THR A 636
REMARK 465 GLU A 637
REMARK 465 LEU A 638
REMARK 465 THR A 639
REMARK 465 ALA A 640
REMARK 465 THR A 641
REMARK 465 PHE A 642
REMARK 465 THR A 643
REMARK 465 LYS A 644
REMARK 465 PHE A 645
REMARK 465 ASP A 646
REMARK 465 ARG A 647
REMARK 465 ASP A 648
REMARK 465 GLY A 649
REMARK 465 ASN A 650
REMARK 465 ARG A 651
REMARK 465 ILE A 652
REMARK 465 LEU A 653
REMARK 465 ASP A 654
REMARK 465 GLU A 655
REMARK 465 LYS A 656
REMARK 465 GLU A 657
REMARK 465 GLN A 658
REMARK 465 GLU A 659
REMARK 465 LYS A 660
REMARK 465 MET A 661
REMARK 465 ARG A 662
REMARK 465 GLN A 663
REMARK 465 ASP A 664
REMARK 465 LEU A 665
REMARK 465 GLU A 666
REMARK 465 GLU A 667
REMARK 465 GLU A 668
REMARK 465 ARG A 669
REMARK 465 VAL A 670
REMARK 465 ALA A 671
REMARK 465 LEU A 672
REMARK 465 ASN A 673
REMARK 465 THR A 674
REMARK 465 GLU A 675
REMARK 465 ILE A 676
REMARK 465 GLU A 677
REMARK 465 LYS A 678
REMARK 465 LEU A 679
REMARK 465 GLY A 680
REMARK 465 ARG A 681
REMARK 465 SER A 682
REMARK 465 ILE A 683
REMARK 465 VAL A 684
REMARK 465 SER A 685
REMARK 465 SER A 686
REMARK 465 PRO A 687
REMARK 465 GLN A 688
REMARK 465 GLY A 689
REMARK 465 LYS A 690
REMARK 465 SER A 691
REMARK 465 GLY A 692
REMARK 465 PRO A 693
REMARK 465 GLU A 694
REMARK 465 ALA A 695
REMARK 465 ALA A 696
REMARK 465 ARG A 697
REMARK 465 ALA A 698
REMARK 465 GLY A 699
REMARK 465 GLY A 700
REMARK 465 TRP A 701
REMARK 465 VAL A 702
REMARK 465 SER A 703
REMARK 465 GLY A 704
REMARK 465 GLU A 705
REMARK 465 GLU A 706
REMARK 465 PHE A 707
REMARK 465 TYR A 708
REMARK 465 MET A 709
REMARK 465 LEU A 710
REMARK 465 THR A 711
REMARK 465 ARG A 712
REMARK 465 ARG A 713
REMARK 465 VAL A 714
REMARK 465 LEU A 715
REMARK 465 GLN A 716
REMARK 465 LEU A 717
REMARK 465 GLU A 718
REMARK 465 THR A 719
REMARK 465 VAL A 720
REMARK 465 LEU A 721
REMARK 465 GLU A 722
REMARK 465 GLY A 723
REMARK 465 VAL A 724
REMARK 465 VAL A 725
REMARK 465 SER A 726
REMARK 465 GLN A 727
REMARK 465 ILE A 728
REMARK 465 ASP A 729
REMARK 465 ALA A 730
REMARK 465 VAL A 731
REMARK 465 GLY A 732
REMARK 465 SER A 733
REMARK 465 LYS A 734
REMARK 465 LEU A 735
REMARK 465 LYS A 736
REMARK 465 MET A 737
REMARK 465 LEU A 738
REMARK 465 GLU A 739
REMARK 465 ARG A 740
REMARK 465 LYS A 741
REMARK 465 GLY A 742
REMARK 465 TRP A 743
REMARK 465 LEU A 744
REMARK 465 ALA A 745
REMARK 465 PRO A 746
REMARK 465 SER A 747
REMARK 465 PRO A 748
REMARK 465 GLY A 749
REMARK 465 VAL A 750
REMARK 465 LYS A 751
REMARK 465 GLU A 752
REMARK 465 GLN A 753
REMARK 465 ALA A 754
REMARK 465 ILE A 755
REMARK 465 TRP A 756
REMARK 465 LYS A 757
REMARK 465 HIS A 758
REMARK 465 PRO A 759
REMARK 465 GLN A 760
REMARK 465 PRO A 761
REMARK 465 ALA A 762
REMARK 465 PRO A 763
REMARK 465 ALA A 764
REMARK 465 VAL A 765
REMARK 465 THR A 766
REMARK 465 PRO A 767
REMARK 465 ASP A 768
REMARK 465 PRO A 769
REMARK 465 TRP A 770
REMARK 465 GLY A 771
REMARK 465 VAL A 772
REMARK 465 GLN A 773
REMARK 465 GLY A 774
REMARK 465 GLY A 775
REMARK 465 GLN A 776
REMARK 465 GLU A 777
REMARK 465 SER A 778
REMARK 465 GLU A 779
REMARK 465 VAL A 780
REMARK 465 PRO A 781
REMARK 465 TYR A 782
REMARK 465 LYS A 783
REMARK 465 ARG A 784
REMARK 465 GLU A 785
REMARK 465 GLU A 786
REMARK 465 GLU A 787
REMARK 465 ALA A 788
REMARK 465 LEU A 789
REMARK 465 GLU A 790
REMARK 465 GLU A 791
REMARK 465 ARG A 792
REMARK 465 ARG A 793
REMARK 465 LEU A 794
REMARK 465 SER A 795
REMARK 465 ARG A 796
REMARK 465 GLY A 797
REMARK 465 GLU A 798
REMARK 465 ILE A 799
REMARK 465 PRO A 800
REMARK 465 THR A 801
REMARK 465 LEU A 802
REMARK 465 GLN A 803
REMARK 465 ARG A 804
REMARK 465 SER A 805
REMARK 465 MET B 1
REMARK 465 ASN B 2
REMARK 465 ALA B 3
REMARK 465 VAL B 4
REMARK 465 GLY B 5
REMARK 465 SER B 6
REMARK 465 PRO B 7
REMARK 465 GLU B 8
REMARK 465 GLY B 9
REMARK 465 GLN B 10
REMARK 465 GLU B 11
REMARK 465 LEU B 12
REMARK 465 GLN B 13
REMARK 465 LYS B 14
REMARK 465 LEU B 15
REMARK 465 GLY B 16
REMARK 465 SER B 17
REMARK 465 GLY B 18
REMARK 465 ALA B 19
REMARK 465 TRP B 20
REMARK 465 ASP B 21
REMARK 465 ASN B 22
REMARK 465 PRO B 23
REMARK 465 ALA B 24
REMARK 465 TYR B 25
REMARK 465 SER B 26
REMARK 465 GLY B 27
REMARK 465 PRO B 28
REMARK 465 PRO B 29
REMARK 465 SER B 30
REMARK 465 PRO B 31
REMARK 465 HIS B 32
REMARK 465 GLY B 33
REMARK 465 THR B 34
REMARK 465 LEU B 35
REMARK 465 ARG B 36
REMARK 465 VAL B 37
REMARK 465 CYS B 38
REMARK 465 THR B 39
REMARK 465 ILE B 40
REMARK 465 SER B 41
REMARK 465 SER B 42
REMARK 465 THR B 43
REMARK 465 GLY B 44
REMARK 465 PRO B 45
REMARK 465 LEU B 46
REMARK 465 GLN B 47
REMARK 465 PRO B 48
REMARK 465 GLN B 49
REMARK 465 PRO B 50
REMARK 465 LYS B 51
REMARK 465 LYS B 52
REMARK 465 PRO B 53
REMARK 465 GLU B 54
REMARK 465 ASP B 55
REMARK 465 GLU B 56
REMARK 465 PRO B 57
REMARK 465 GLN B 58
REMARK 465 GLU B 59
REMARK 465 THR B 60
REMARK 465 ALA B 61
REMARK 465 TYR B 62
REMARK 465 ARG B 63
REMARK 465 THR B 64
REMARK 465 GLN B 65
REMARK 465 VAL B 66
REMARK 465 SER B 67
REMARK 465 SER B 68
REMARK 465 CYS B 69
REMARK 465 CYS B 70
REMARK 465 LEU B 71
REMARK 465 HIS B 72
REMARK 465 ILE B 73
REMARK 465 CYS B 74
REMARK 465 GLN B 75
REMARK 465 GLY B 76
REMARK 465 ILE B 77
REMARK 465 ARG B 78
REMARK 465 GLY B 79
REMARK 465 LEU B 80
REMARK 465 TRP B 81
REMARK 465 GLY B 82
REMARK 465 THR B 83
REMARK 465 THR B 84
REMARK 465 LEU B 85
REMARK 465 THR B 86
REMARK 465 GLU B 87
REMARK 465 ASN B 88
REMARK 465 THR B 89
REMARK 465 ALA B 90
REMARK 465 GLU B 91
REMARK 465 ASN B 92
REMARK 465 ARG B 93
REMARK 465 GLU B 94
REMARK 465 LEU B 95
REMARK 465 TYR B 96
REMARK 465 ILE B 97
REMARK 465 LYS B 98
REMARK 465 THR B 99
REMARK 465 THR B 100
REMARK 465 LYS B 173
REMARK 465 TRP B 174
REMARK 465 TYR B 175
REMARK 465 ASN B 176
REMARK 465 ASN B 177
REMARK 465 GLN B 178
REMARK 465 SER B 179
REMARK 465 LEU B 180
REMARK 465 TYR B 344
REMARK 465 VAL B 345
REMARK 465 SER B 346
REMARK 465 ASN B 347
REMARK 465 TRP B 348
REMARK 465 ASP B 349
REMARK 465 PHE B 350
REMARK 465 LEU B 382
REMARK 465 SER B 383
REMARK 465 ILE B 457
REMARK 465 SER B 458
REMARK 465 PHE B 459
REMARK 465 ASN B 460
REMARK 465 LYS B 461
REMARK 465 THR B 462
REMARK 465 MET B 463
REMARK 465 THR B 464
REMARK 465 GLN B 465
REMARK 465 LEU B 466
REMARK 465 SER B 467
REMARK 465 SER B 468
REMARK 465 THR B 469
REMARK 465 LEU B 470
REMARK 465 ALA B 471
REMARK 465 ARG B 472
REMARK 465 CYS B 473
REMARK 465 ALA B 474
REMARK 465 LYS B 475
REMARK 465 ASP B 476
REMARK 465 ILE B 477
REMARK 465 LEU B 478
REMARK 465 GLY B 479
REMARK 465 ASP B 562
REMARK 465 THR B 563
REMARK 465 TYR B 564
REMARK 465 SER B 565
REMARK 465 GLU B 566
REMARK 465 VAL B 567
REMARK 465 LYS B 568
REMARK 465 GLU B 569
REMARK 465 GLU B 570
REMARK 465 LEU B 571
REMARK 465 ALA B 572
REMARK 465 GLY B 573
REMARK 465 GLN B 574
REMARK 465 LYS B 575
REMARK 465 ASP B 576
REMARK 465 GLU B 577
REMARK 465 LEU B 578
REMARK 465 GLN B 579
REMARK 465 LEU B 580
REMARK 465 SER B 581
REMARK 465 ASP B 582
REMARK 465 LEU B 583
REMARK 465 LEU B 584
REMARK 465 LYS B 585
REMARK 465 GLN B 586
REMARK 465 GLY B 587
REMARK 465 TYR B 588
REMARK 465 ASN B 589
REMARK 465 LYS B 590
REMARK 465 THR B 591
REMARK 465 LEU B 592
REMARK 465 LEU B 593
REMARK 465 ARG B 594
REMARK 465 LEU B 595
REMARK 465 ARG B 596
REMARK 465 LEU B 597
REMARK 465 ARG B 598
REMARK 465 LYS B 599
REMARK 465 GLU B 600
REMARK 465 ARG B 601
REMARK 465 VAL B 602
REMARK 465 SER B 603
REMARK 465 ASP B 604
REMARK 465 VAL B 605
REMARK 465 GLN B 606
REMARK 465 LYS B 607
REMARK 465 VAL B 608
REMARK 465 LEU B 609
REMARK 465 GLN B 610
REMARK 465 GLY B 611
REMARK 465 GLY B 612
REMARK 465 GLU B 613
REMARK 465 GLN B 614
REMARK 465 GLU B 615
REMARK 465 ILE B 616
REMARK 465 GLN B 617
REMARK 465 PHE B 618
REMARK 465 GLU B 619
REMARK 465 ASP B 620
REMARK 465 PHE B 621
REMARK 465 THR B 622
REMARK 465 ASN B 623
REMARK 465 THR B 624
REMARK 465 LEU B 625
REMARK 465 ARG B 626
REMARK 465 GLU B 627
REMARK 465 LEU B 628
REMARK 465 GLY B 629
REMARK 465 HIS B 630
REMARK 465 ALA B 631
REMARK 465 GLU B 632
REMARK 465 HIS B 633
REMARK 465 GLU B 634
REMARK 465 ILE B 635
REMARK 465 THR B 636
REMARK 465 GLU B 637
REMARK 465 LEU B 638
REMARK 465 THR B 639
REMARK 465 ALA B 640
REMARK 465 THR B 641
REMARK 465 PHE B 642
REMARK 465 THR B 643
REMARK 465 LYS B 644
REMARK 465 PHE B 645
REMARK 465 ASP B 646
REMARK 465 ARG B 647
REMARK 465 ASP B 648
REMARK 465 GLY B 649
REMARK 465 ASN B 650
REMARK 465 ARG B 651
REMARK 465 ILE B 652
REMARK 465 LEU B 653
REMARK 465 ASP B 654
REMARK 465 GLU B 655
REMARK 465 LYS B 656
REMARK 465 GLU B 657
REMARK 465 GLN B 658
REMARK 465 GLU B 659
REMARK 465 LYS B 660
REMARK 465 MET B 661
REMARK 465 ARG B 662
REMARK 465 GLN B 663
REMARK 465 ASP B 664
REMARK 465 LEU B 665
REMARK 465 GLU B 666
REMARK 465 GLU B 667
REMARK 465 GLU B 668
REMARK 465 ARG B 669
REMARK 465 VAL B 670
REMARK 465 ALA B 671
REMARK 465 LEU B 672
REMARK 465 ASN B 673
REMARK 465 THR B 674
REMARK 465 GLU B 675
REMARK 465 ILE B 676
REMARK 465 GLU B 677
REMARK 465 LYS B 678
REMARK 465 LEU B 679
REMARK 465 GLY B 680
REMARK 465 ARG B 681
REMARK 465 SER B 682
REMARK 465 ILE B 683
REMARK 465 VAL B 684
REMARK 465 SER B 685
REMARK 465 SER B 686
REMARK 465 PRO B 687
REMARK 465 GLN B 688
REMARK 465 GLY B 689
REMARK 465 LYS B 690
REMARK 465 SER B 691
REMARK 465 GLY B 692
REMARK 465 PRO B 693
REMARK 465 GLU B 694
REMARK 465 ALA B 695
REMARK 465 ALA B 696
REMARK 465 ARG B 697
REMARK 465 ALA B 698
REMARK 465 GLY B 699
REMARK 465 GLY B 700
REMARK 465 TRP B 701
REMARK 465 VAL B 702
REMARK 465 SER B 703
REMARK 465 GLY B 704
REMARK 465 GLU B 705
REMARK 465 GLU B 706
REMARK 465 PHE B 707
REMARK 465 TYR B 708
REMARK 465 MET B 709
REMARK 465 LEU B 710
REMARK 465 THR B 711
REMARK 465 ARG B 712
REMARK 465 ARG B 713
REMARK 465 VAL B 714
REMARK 465 LEU B 715
REMARK 465 GLN B 716
REMARK 465 LEU B 717
REMARK 465 GLU B 718
REMARK 465 THR B 719
REMARK 465 VAL B 720
REMARK 465 LEU B 721
REMARK 465 GLU B 722
REMARK 465 GLY B 723
REMARK 465 VAL B 724
REMARK 465 VAL B 725
REMARK 465 SER B 726
REMARK 465 GLN B 727
REMARK 465 ILE B 728
REMARK 465 ASP B 729
REMARK 465 ALA B 730
REMARK 465 VAL B 731
REMARK 465 GLY B 732
REMARK 465 SER B 733
REMARK 465 LYS B 734
REMARK 465 LEU B 735
REMARK 465 LYS B 736
REMARK 465 MET B 737
REMARK 465 LEU B 738
REMARK 465 GLU B 739
REMARK 465 ARG B 740
REMARK 465 LYS B 741
REMARK 465 GLY B 742
REMARK 465 TRP B 743
REMARK 465 LEU B 744
REMARK 465 ALA B 745
REMARK 465 PRO B 746
REMARK 465 SER B 747
REMARK 465 PRO B 748
REMARK 465 GLY B 749
REMARK 465 VAL B 750
REMARK 465 LYS B 751
REMARK 465 GLU B 752
REMARK 465 GLN B 753
REMARK 465 ALA B 754
REMARK 465 ILE B 755
REMARK 465 TRP B 756
REMARK 465 LYS B 757
REMARK 465 HIS B 758
REMARK 465 PRO B 759
REMARK 465 GLN B 760
REMARK 465 PRO B 761
REMARK 465 ALA B 762
REMARK 465 PRO B 763
REMARK 465 ALA B 764
REMARK 465 VAL B 765
REMARK 465 THR B 766
REMARK 465 PRO B 767
REMARK 465 ASP B 768
REMARK 465 PRO B 769
REMARK 465 TRP B 770
REMARK 465 GLY B 771
REMARK 465 VAL B 772
REMARK 465 GLN B 773
REMARK 465 GLY B 774
REMARK 465 GLY B 775
REMARK 465 GLN B 776
REMARK 465 GLU B 777
REMARK 465 SER B 778
REMARK 465 GLU B 779
REMARK 465 VAL B 780
REMARK 465 PRO B 781
REMARK 465 TYR B 782
REMARK 465 LYS B 783
REMARK 465 ARG B 784
REMARK 465 GLU B 785
REMARK 465 GLU B 786
REMARK 465 GLU B 787
REMARK 465 ALA B 788
REMARK 465 LEU B 789
REMARK 465 GLU B 790
REMARK 465 GLU B 791
REMARK 465 ARG B 792
REMARK 465 ARG B 793
REMARK 465 LEU B 794
REMARK 465 SER B 795
REMARK 465 ARG B 796
REMARK 465 GLY B 797
REMARK 465 GLU B 798
REMARK 465 ILE B 799
REMARK 465 PRO B 800
REMARK 465 THR B 801
REMARK 465 LEU B 802
REMARK 465 GLN B 803
REMARK 465 ARG B 804
REMARK 465 SER B 805
REMARK 465 MET C 1
REMARK 465 ASN C 2
REMARK 465 ALA C 3
REMARK 465 VAL C 4
REMARK 465 GLY C 5
REMARK 465 SER C 6
REMARK 465 PRO C 7
REMARK 465 GLU C 8
REMARK 465 GLY C 9
REMARK 465 GLN C 10
REMARK 465 GLU C 11
REMARK 465 LEU C 12
REMARK 465 GLN C 13
REMARK 465 LYS C 14
REMARK 465 LEU C 15
REMARK 465 GLY C 16
REMARK 465 SER C 17
REMARK 465 GLY C 18
REMARK 465 ALA C 19
REMARK 465 TRP C 20
REMARK 465 ASP C 21
REMARK 465 ASN C 22
REMARK 465 PRO C 23
REMARK 465 ALA C 24
REMARK 465 TYR C 25
REMARK 465 SER C 26
REMARK 465 GLY C 27
REMARK 465 PRO C 28
REMARK 465 PRO C 29
REMARK 465 SER C 30
REMARK 465 PRO C 31
REMARK 465 HIS C 32
REMARK 465 GLY C 33
REMARK 465 THR C 34
REMARK 465 LEU C 35
REMARK 465 ARG C 36
REMARK 465 VAL C 37
REMARK 465 CYS C 38
REMARK 465 THR C 39
REMARK 465 ILE C 40
REMARK 465 SER C 41
REMARK 465 SER C 42
REMARK 465 THR C 43
REMARK 465 GLY C 44
REMARK 465 PRO C 45
REMARK 465 LEU C 46
REMARK 465 GLN C 47
REMARK 465 PRO C 48
REMARK 465 GLN C 49
REMARK 465 PRO C 50
REMARK 465 LYS C 51
REMARK 465 LYS C 52
REMARK 465 PRO C 53
REMARK 465 GLU C 54
REMARK 465 ASP C 55
REMARK 465 GLU C 56
REMARK 465 PRO C 57
REMARK 465 GLN C 58
REMARK 465 GLU C 59
REMARK 465 THR C 60
REMARK 465 ALA C 61
REMARK 465 TYR C 62
REMARK 465 ARG C 63
REMARK 465 THR C 64
REMARK 465 GLN C 65
REMARK 465 VAL C 66
REMARK 465 SER C 67
REMARK 465 SER C 68
REMARK 465 CYS C 69
REMARK 465 CYS C 70
REMARK 465 LEU C 71
REMARK 465 HIS C 72
REMARK 465 ILE C 73
REMARK 465 CYS C 74
REMARK 465 GLN C 75
REMARK 465 GLY C 76
REMARK 465 ILE C 77
REMARK 465 ARG C 78
REMARK 465 GLY C 79
REMARK 465 LEU C 80
REMARK 465 TRP C 81
REMARK 465 GLY C 82
REMARK 465 THR C 83
REMARK 465 THR C 84
REMARK 465 LEU C 85
REMARK 465 THR C 86
REMARK 465 GLU C 87
REMARK 465 ASN C 88
REMARK 465 THR C 89
REMARK 465 ALA C 90
REMARK 465 GLU C 91
REMARK 465 ASN C 92
REMARK 465 ARG C 93
REMARK 465 GLU C 94
REMARK 465 LEU C 95
REMARK 465 TYR C 96
REMARK 465 ILE C 97
REMARK 465 LYS C 98
REMARK 465 THR C 99
REMARK 465 THR C 100
REMARK 465 LYS C 173
REMARK 465 TRP C 174
REMARK 465 TYR C 175
REMARK 465 ASN C 176
REMARK 465 ASN C 177
REMARK 465 GLN C 178
REMARK 465 SER C 179
REMARK 465 LEU C 180
REMARK 465 TYR C 344
REMARK 465 VAL C 345
REMARK 465 SER C 346
REMARK 465 ASN C 347
REMARK 465 TRP C 348
REMARK 465 ASP C 349
REMARK 465 PHE C 350
REMARK 465 LEU C 382
REMARK 465 SER C 383
REMARK 465 ILE C 457
REMARK 465 SER C 458
REMARK 465 PHE C 459
REMARK 465 ASN C 460
REMARK 465 LYS C 461
REMARK 465 THR C 462
REMARK 465 MET C 463
REMARK 465 THR C 464
REMARK 465 GLN C 465
REMARK 465 LEU C 466
REMARK 465 SER C 467
REMARK 465 SER C 468
REMARK 465 THR C 469
REMARK 465 LEU C 470
REMARK 465 ALA C 471
REMARK 465 ARG C 472
REMARK 465 CYS C 473
REMARK 465 ALA C 474
REMARK 465 LYS C 475
REMARK 465 ASP C 476
REMARK 465 ILE C 477
REMARK 465 LEU C 478
REMARK 465 GLY C 479
REMARK 465 ASP C 562
REMARK 465 THR C 563
REMARK 465 TYR C 564
REMARK 465 SER C 565
REMARK 465 GLU C 566
REMARK 465 VAL C 567
REMARK 465 LYS C 568
REMARK 465 GLU C 569
REMARK 465 GLU C 570
REMARK 465 LEU C 571
REMARK 465 ALA C 572
REMARK 465 GLY C 573
REMARK 465 GLN C 574
REMARK 465 LYS C 575
REMARK 465 ASP C 576
REMARK 465 GLU C 577
REMARK 465 LEU C 578
REMARK 465 GLN C 579
REMARK 465 LEU C 580
REMARK 465 SER C 581
REMARK 465 ASP C 582
REMARK 465 LEU C 583
REMARK 465 LEU C 584
REMARK 465 LYS C 585
REMARK 465 GLN C 586
REMARK 465 GLY C 587
REMARK 465 TYR C 588
REMARK 465 ASN C 589
REMARK 465 LYS C 590
REMARK 465 THR C 591
REMARK 465 LEU C 592
REMARK 465 LEU C 593
REMARK 465 ARG C 594
REMARK 465 LEU C 595
REMARK 465 ARG C 596
REMARK 465 LEU C 597
REMARK 465 ARG C 598
REMARK 465 LYS C 599
REMARK 465 GLU C 600
REMARK 465 ARG C 601
REMARK 465 VAL C 602
REMARK 465 SER C 603
REMARK 465 ASP C 604
REMARK 465 VAL C 605
REMARK 465 GLN C 606
REMARK 465 LYS C 607
REMARK 465 VAL C 608
REMARK 465 LEU C 609
REMARK 465 GLN C 610
REMARK 465 GLY C 611
REMARK 465 GLY C 612
REMARK 465 GLU C 613
REMARK 465 GLN C 614
REMARK 465 GLU C 615
REMARK 465 ILE C 616
REMARK 465 GLN C 617
REMARK 465 PHE C 618
REMARK 465 GLU C 619
REMARK 465 ASP C 620
REMARK 465 PHE C 621
REMARK 465 THR C 622
REMARK 465 ASN C 623
REMARK 465 THR C 624
REMARK 465 LEU C 625
REMARK 465 ARG C 626
REMARK 465 GLU C 627
REMARK 465 LEU C 628
REMARK 465 GLY C 629
REMARK 465 HIS C 630
REMARK 465 ALA C 631
REMARK 465 GLU C 632
REMARK 465 HIS C 633
REMARK 465 GLU C 634
REMARK 465 ILE C 635
REMARK 465 THR C 636
REMARK 465 GLU C 637
REMARK 465 LEU C 638
REMARK 465 THR C 639
REMARK 465 ALA C 640
REMARK 465 THR C 641
REMARK 465 PHE C 642
REMARK 465 THR C 643
REMARK 465 LYS C 644
REMARK 465 PHE C 645
REMARK 465 ASP C 646
REMARK 465 ARG C 647
REMARK 465 ASP C 648
REMARK 465 GLY C 649
REMARK 465 ASN C 650
REMARK 465 ARG C 651
REMARK 465 ILE C 652
REMARK 465 LEU C 653
REMARK 465 ASP C 654
REMARK 465 GLU C 655
REMARK 465 LYS C 656
REMARK 465 GLU C 657
REMARK 465 GLN C 658
REMARK 465 GLU C 659
REMARK 465 LYS C 660
REMARK 465 MET C 661
REMARK 465 ARG C 662
REMARK 465 GLN C 663
REMARK 465 ASP C 664
REMARK 465 LEU C 665
REMARK 465 GLU C 666
REMARK 465 GLU C 667
REMARK 465 GLU C 668
REMARK 465 ARG C 669
REMARK 465 VAL C 670
REMARK 465 ALA C 671
REMARK 465 LEU C 672
REMARK 465 ASN C 673
REMARK 465 THR C 674
REMARK 465 GLU C 675
REMARK 465 ILE C 676
REMARK 465 GLU C 677
REMARK 465 LYS C 678
REMARK 465 LEU C 679
REMARK 465 GLY C 680
REMARK 465 ARG C 681
REMARK 465 SER C 682
REMARK 465 ILE C 683
REMARK 465 VAL C 684
REMARK 465 SER C 685
REMARK 465 SER C 686
REMARK 465 PRO C 687
REMARK 465 GLN C 688
REMARK 465 GLY C 689
REMARK 465 LYS C 690
REMARK 465 SER C 691
REMARK 465 GLY C 692
REMARK 465 PRO C 693
REMARK 465 GLU C 694
REMARK 465 ALA C 695
REMARK 465 ALA C 696
REMARK 465 ARG C 697
REMARK 465 ALA C 698
REMARK 465 GLY C 699
REMARK 465 GLY C 700
REMARK 465 TRP C 701
REMARK 465 VAL C 702
REMARK 465 SER C 703
REMARK 465 GLY C 704
REMARK 465 GLU C 705
REMARK 465 GLU C 706
REMARK 465 PHE C 707
REMARK 465 TYR C 708
REMARK 465 MET C 709
REMARK 465 LEU C 710
REMARK 465 THR C 711
REMARK 465 ARG C 712
REMARK 465 ARG C 713
REMARK 465 VAL C 714
REMARK 465 LEU C 715
REMARK 465 GLN C 716
REMARK 465 LEU C 717
REMARK 465 GLU C 718
REMARK 465 THR C 719
REMARK 465 VAL C 720
REMARK 465 LEU C 721
REMARK 465 GLU C 722
REMARK 465 GLY C 723
REMARK 465 VAL C 724
REMARK 465 VAL C 725
REMARK 465 SER C 726
REMARK 465 GLN C 727
REMARK 465 ILE C 728
REMARK 465 ASP C 729
REMARK 465 ALA C 730
REMARK 465 VAL C 731
REMARK 465 GLY C 732
REMARK 465 SER C 733
REMARK 465 LYS C 734
REMARK 465 LEU C 735
REMARK 465 LYS C 736
REMARK 465 MET C 737
REMARK 465 LEU C 738
REMARK 465 GLU C 739
REMARK 465 ARG C 740
REMARK 465 LYS C 741
REMARK 465 GLY C 742
REMARK 465 TRP C 743
REMARK 465 LEU C 744
REMARK 465 ALA C 745
REMARK 465 PRO C 746
REMARK 465 SER C 747
REMARK 465 PRO C 748
REMARK 465 GLY C 749
REMARK 465 VAL C 750
REMARK 465 LYS C 751
REMARK 465 GLU C 752
REMARK 465 GLN C 753
REMARK 465 ALA C 754
REMARK 465 ILE C 755
REMARK 465 TRP C 756
REMARK 465 LYS C 757
REMARK 465 HIS C 758
REMARK 465 PRO C 759
REMARK 465 GLN C 760
REMARK 465 PRO C 761
REMARK 465 ALA C 762
REMARK 465 PRO C 763
REMARK 465 ALA C 764
REMARK 465 VAL C 765
REMARK 465 THR C 766
REMARK 465 PRO C 767
REMARK 465 ASP C 768
REMARK 465 PRO C 769
REMARK 465 TRP C 770
REMARK 465 GLY C 771
REMARK 465 VAL C 772
REMARK 465 GLN C 773
REMARK 465 GLY C 774
REMARK 465 GLY C 775
REMARK 465 GLN C 776
REMARK 465 GLU C 777
REMARK 465 SER C 778
REMARK 465 GLU C 779
REMARK 465 VAL C 780
REMARK 465 PRO C 781
REMARK 465 TYR C 782
REMARK 465 LYS C 783
REMARK 465 ARG C 784
REMARK 465 GLU C 785
REMARK 465 GLU C 786
REMARK 465 GLU C 787
REMARK 465 ALA C 788
REMARK 465 LEU C 789
REMARK 465 GLU C 790
REMARK 465 GLU C 791
REMARK 465 ARG C 792
REMARK 465 ARG C 793
REMARK 465 LEU C 794
REMARK 465 SER C 795
REMARK 465 ARG C 796
REMARK 465 GLY C 797
REMARK 465 GLU C 798
REMARK 465 ILE C 799
REMARK 465 PRO C 800
REMARK 465 THR C 801
REMARK 465 LEU C 802
REMARK 465 GLN C 803
REMARK 465 ARG C 804
REMARK 465 SER C 805
REMARK 465 MET D 1
REMARK 465 ASN D 2
REMARK 465 ALA D 3
REMARK 465 VAL D 4
REMARK 465 GLY D 5
REMARK 465 SER D 6
REMARK 465 PRO D 7
REMARK 465 GLU D 8
REMARK 465 GLY D 9
REMARK 465 GLN D 10
REMARK 465 GLU D 11
REMARK 465 LEU D 12
REMARK 465 GLN D 13
REMARK 465 LYS D 14
REMARK 465 LEU D 15
REMARK 465 GLY D 16
REMARK 465 SER D 17
REMARK 465 GLY D 18
REMARK 465 ALA D 19
REMARK 465 TRP D 20
REMARK 465 ASP D 21
REMARK 465 ASN D 22
REMARK 465 PRO D 23
REMARK 465 ALA D 24
REMARK 465 TYR D 25
REMARK 465 SER D 26
REMARK 465 GLY D 27
REMARK 465 PRO D 28
REMARK 465 PRO D 29
REMARK 465 SER D 30
REMARK 465 PRO D 31
REMARK 465 HIS D 32
REMARK 465 GLY D 33
REMARK 465 THR D 34
REMARK 465 LEU D 35
REMARK 465 ARG D 36
REMARK 465 VAL D 37
REMARK 465 CYS D 38
REMARK 465 THR D 39
REMARK 465 ILE D 40
REMARK 465 SER D 41
REMARK 465 SER D 42
REMARK 465 THR D 43
REMARK 465 GLY D 44
REMARK 465 PRO D 45
REMARK 465 LEU D 46
REMARK 465 GLN D 47
REMARK 465 PRO D 48
REMARK 465 GLN D 49
REMARK 465 PRO D 50
REMARK 465 LYS D 51
REMARK 465 LYS D 52
REMARK 465 PRO D 53
REMARK 465 GLU D 54
REMARK 465 ASP D 55
REMARK 465 GLU D 56
REMARK 465 PRO D 57
REMARK 465 GLN D 58
REMARK 465 GLU D 59
REMARK 465 THR D 60
REMARK 465 ALA D 61
REMARK 465 TYR D 62
REMARK 465 ARG D 63
REMARK 465 THR D 64
REMARK 465 GLN D 65
REMARK 465 VAL D 66
REMARK 465 SER D 67
REMARK 465 SER D 68
REMARK 465 CYS D 69
REMARK 465 CYS D 70
REMARK 465 LEU D 71
REMARK 465 HIS D 72
REMARK 465 ILE D 73
REMARK 465 CYS D 74
REMARK 465 GLN D 75
REMARK 465 GLY D 76
REMARK 465 ILE D 77
REMARK 465 ARG D 78
REMARK 465 GLY D 79
REMARK 465 LEU D 80
REMARK 465 TRP D 81
REMARK 465 GLY D 82
REMARK 465 THR D 83
REMARK 465 THR D 84
REMARK 465 LEU D 85
REMARK 465 THR D 86
REMARK 465 GLU D 87
REMARK 465 ASN D 88
REMARK 465 THR D 89
REMARK 465 ALA D 90
REMARK 465 GLU D 91
REMARK 465 ASN D 92
REMARK 465 ARG D 93
REMARK 465 GLU D 94
REMARK 465 LEU D 95
REMARK 465 TYR D 96
REMARK 465 ILE D 97
REMARK 465 LYS D 98
REMARK 465 THR D 99
REMARK 465 THR D 100
REMARK 465 LYS D 173
REMARK 465 TRP D 174
REMARK 465 TYR D 175
REMARK 465 ASN D 176
REMARK 465 ASN D 177
REMARK 465 GLN D 178
REMARK 465 SER D 179
REMARK 465 LEU D 180
REMARK 465 TYR D 344
REMARK 465 VAL D 345
REMARK 465 SER D 346
REMARK 465 ASN D 347
REMARK 465 TRP D 348
REMARK 465 ASP D 349
REMARK 465 PHE D 350
REMARK 465 LEU D 382
REMARK 465 SER D 383
REMARK 465 ILE D 457
REMARK 465 SER D 458
REMARK 465 PHE D 459
REMARK 465 ASN D 460
REMARK 465 LYS D 461
REMARK 465 THR D 462
REMARK 465 MET D 463
REMARK 465 THR D 464
REMARK 465 GLN D 465
REMARK 465 LEU D 466
REMARK 465 SER D 467
REMARK 465 SER D 468
REMARK 465 THR D 469
REMARK 465 LEU D 470
REMARK 465 ALA D 471
REMARK 465 ARG D 472
REMARK 465 CYS D 473
REMARK 465 ALA D 474
REMARK 465 LYS D 475
REMARK 465 ASP D 476
REMARK 465 ILE D 477
REMARK 465 LEU D 478
REMARK 465 GLY D 479
REMARK 465 ASP D 562
REMARK 465 THR D 563
REMARK 465 TYR D 564
REMARK 465 SER D 565
REMARK 465 GLU D 566
REMARK 465 VAL D 567
REMARK 465 LYS D 568
REMARK 465 GLU D 569
REMARK 465 GLU D 570
REMARK 465 LEU D 571
REMARK 465 ALA D 572
REMARK 465 GLY D 573
REMARK 465 GLN D 574
REMARK 465 LYS D 575
REMARK 465 ASP D 576
REMARK 465 GLU D 577
REMARK 465 LEU D 578
REMARK 465 GLN D 579
REMARK 465 LEU D 580
REMARK 465 SER D 581
REMARK 465 ASP D 582
REMARK 465 LEU D 583
REMARK 465 LEU D 584
REMARK 465 LYS D 585
REMARK 465 GLN D 586
REMARK 465 GLY D 587
REMARK 465 TYR D 588
REMARK 465 ASN D 589
REMARK 465 LYS D 590
REMARK 465 THR D 591
REMARK 465 LEU D 592
REMARK 465 LEU D 593
REMARK 465 ARG D 594
REMARK 465 LEU D 595
REMARK 465 ARG D 596
REMARK 465 LEU D 597
REMARK 465 ARG D 598
REMARK 465 LYS D 599
REMARK 465 GLU D 600
REMARK 465 ARG D 601
REMARK 465 VAL D 602
REMARK 465 SER D 603
REMARK 465 ASP D 604
REMARK 465 VAL D 605
REMARK 465 GLN D 606
REMARK 465 LYS D 607
REMARK 465 VAL D 608
REMARK 465 LEU D 609
REMARK 465 GLN D 610
REMARK 465 GLY D 611
REMARK 465 GLY D 612
REMARK 465 GLU D 613
REMARK 465 GLN D 614
REMARK 465 GLU D 615
REMARK 465 ILE D 616
REMARK 465 GLN D 617
REMARK 465 PHE D 618
REMARK 465 GLU D 619
REMARK 465 ASP D 620
REMARK 465 PHE D 621
REMARK 465 THR D 622
REMARK 465 ASN D 623
REMARK 465 THR D 624
REMARK 465 LEU D 625
REMARK 465 ARG D 626
REMARK 465 GLU D 627
REMARK 465 LEU D 628
REMARK 465 GLY D 629
REMARK 465 HIS D 630
REMARK 465 ALA D 631
REMARK 465 GLU D 632
REMARK 465 HIS D 633
REMARK 465 GLU D 634
REMARK 465 ILE D 635
REMARK 465 THR D 636
REMARK 465 GLU D 637
REMARK 465 LEU D 638
REMARK 465 THR D 639
REMARK 465 ALA D 640
REMARK 465 THR D 641
REMARK 465 PHE D 642
REMARK 465 THR D 643
REMARK 465 LYS D 644
REMARK 465 PHE D 645
REMARK 465 ASP D 646
REMARK 465 ARG D 647
REMARK 465 ASP D 648
REMARK 465 GLY D 649
REMARK 465 ASN D 650
REMARK 465 ARG D 651
REMARK 465 ILE D 652
REMARK 465 LEU D 653
REMARK 465 ASP D 654
REMARK 465 GLU D 655
REMARK 465 LYS D 656
REMARK 465 GLU D 657
REMARK 465 GLN D 658
REMARK 465 GLU D 659
REMARK 465 LYS D 660
REMARK 465 MET D 661
REMARK 465 ARG D 662
REMARK 465 GLN D 663
REMARK 465 ASP D 664
REMARK 465 LEU D 665
REMARK 465 GLU D 666
REMARK 465 GLU D 667
REMARK 465 GLU D 668
REMARK 465 ARG D 669
REMARK 465 VAL D 670
REMARK 465 ALA D 671
REMARK 465 LEU D 672
REMARK 465 ASN D 673
REMARK 465 THR D 674
REMARK 465 GLU D 675
REMARK 465 ILE D 676
REMARK 465 GLU D 677
REMARK 465 LYS D 678
REMARK 465 LEU D 679
REMARK 465 GLY D 680
REMARK 465 ARG D 681
REMARK 465 SER D 682
REMARK 465 ILE D 683
REMARK 465 VAL D 684
REMARK 465 SER D 685
REMARK 465 SER D 686
REMARK 465 PRO D 687
REMARK 465 GLN D 688
REMARK 465 GLY D 689
REMARK 465 LYS D 690
REMARK 465 SER D 691
REMARK 465 GLY D 692
REMARK 465 PRO D 693
REMARK 465 GLU D 694
REMARK 465 ALA D 695
REMARK 465 ALA D 696
REMARK 465 ARG D 697
REMARK 465 ALA D 698
REMARK 465 GLY D 699
REMARK 465 GLY D 700
REMARK 465 TRP D 701
REMARK 465 VAL D 702
REMARK 465 SER D 703
REMARK 465 GLY D 704
REMARK 465 GLU D 705
REMARK 465 GLU D 706
REMARK 465 PHE D 707
REMARK 465 TYR D 708
REMARK 465 MET D 709
REMARK 465 LEU D 710
REMARK 465 THR D 711
REMARK 465 ARG D 712
REMARK 465 ARG D 713
REMARK 465 VAL D 714
REMARK 465 LEU D 715
REMARK 465 GLN D 716
REMARK 465 LEU D 717
REMARK 465 GLU D 718
REMARK 465 THR D 719
REMARK 465 VAL D 720
REMARK 465 LEU D 721
REMARK 465 GLU D 722
REMARK 465 GLY D 723
REMARK 465 VAL D 724
REMARK 465 VAL D 725
REMARK 465 SER D 726
REMARK 465 GLN D 727
REMARK 465 ILE D 728
REMARK 465 ASP D 729
REMARK 465 ALA D 730
REMARK 465 VAL D 731
REMARK 465 GLY D 732
REMARK 465 SER D 733
REMARK 465 LYS D 734
REMARK 465 LEU D 735
REMARK 465 LYS D 736
REMARK 465 MET D 737
REMARK 465 LEU D 738
REMARK 465 GLU D 739
REMARK 465 ARG D 740
REMARK 465 LYS D 741
REMARK 465 GLY D 742
REMARK 465 TRP D 743
REMARK 465 LEU D 744
REMARK 465 ALA D 745
REMARK 465 PRO D 746
REMARK 465 SER D 747
REMARK 465 PRO D 748
REMARK 465 GLY D 749
REMARK 465 VAL D 750
REMARK 465 LYS D 751
REMARK 465 GLU D 752
REMARK 465 GLN D 753
REMARK 465 ALA D 754
REMARK 465 ILE D 755
REMARK 465 TRP D 756
REMARK 465 LYS D 757
REMARK 465 HIS D 758
REMARK 465 PRO D 759
REMARK 465 GLN D 760
REMARK 465 PRO D 761
REMARK 465 ALA D 762
REMARK 465 PRO D 763
REMARK 465 ALA D 764
REMARK 465 VAL D 765
REMARK 465 THR D 766
REMARK 465 PRO D 767
REMARK 465 ASP D 768
REMARK 465 PRO D 769
REMARK 465 TRP D 770
REMARK 465 GLY D 771
REMARK 465 VAL D 772
REMARK 465 GLN D 773
REMARK 465 GLY D 774
REMARK 465 GLY D 775
REMARK 465 GLN D 776
REMARK 465 GLU D 777
REMARK 465 SER D 778
REMARK 465 GLU D 779
REMARK 465 VAL D 780
REMARK 465 PRO D 781
REMARK 465 TYR D 782
REMARK 465 LYS D 783
REMARK 465 ARG D 784
REMARK 465 GLU D 785
REMARK 465 GLU D 786
REMARK 465 GLU D 787
REMARK 465 ALA D 788
REMARK 465 LEU D 789
REMARK 465 GLU D 790
REMARK 465 GLU D 791
REMARK 465 ARG D 792
REMARK 465 ARG D 793
REMARK 465 LEU D 794
REMARK 465 SER D 795
REMARK 465 ARG D 796
REMARK 465 GLY D 797
REMARK 465 GLU D 798
REMARK 465 ILE D 799
REMARK 465 PRO D 800
REMARK 465 THR D 801
REMARK 465 LEU D 802
REMARK 465 GLN D 803
REMARK 465 ARG D 804
REMARK 465 SER D 805
REMARK 470
REMARK 470 MISSING ATOM
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;
REMARK 470 I=INSERTION CODE):
REMARK 470 M RES CSSEQI ATOMS
REMARK 470 LEU A 101 CG CD1 CD2
REMARK 470 ARG A 102 CG CD NE CZ NH1 NH2
REMARK 470 LEU A 105 CG CD1 CD2
REMARK 470 TYR A 107 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 ASP A 113 CG OD1 OD2
REMARK 470 LEU A 117 CG CD1 CD2
REMARK 470 MET A 121 CG SD CE
REMARK 470 GLU A 135 CG CD OE1 OE2
REMARK 470 ASP A 156 CG OD1 OD2
REMARK 470 ASP A 167 CG OD1 OD2
REMARK 470 GLU A 191 CG CD OE1 OE2
REMARK 470 GLU A 214 CG CD OE1 OE2
REMARK 470 ARG A 278 CG CD NE CZ NH1 NH2
REMARK 470 LEU A 292 CG CD1 CD2
REMARK 470 PHE A 315 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 ARG A 343 CG CD NE CZ NH1 NH2
REMARK 470 GLU A 369 CG CD OE1 OE2
REMARK 470 GLU A 370 CG CD OE1 OE2
REMARK 470 GLU A 373 CG CD OE1 OE2
REMARK 470 HIS A 375 CG ND1 CD2 CE1 NE2
REMARK 470 TYR A 381 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 ILE A 385 CG1 CG2 CD1
REMARK 470 ASN A 387 CG OD1 ND2
REMARK 470 LEU A 391 CG CD1 CD2
REMARK 470 GLU A 429 CG CD OE1 OE2
REMARK 470 MET A 441 CG SD CE
REMARK 470 ILE A 451 CG1 CG2 CD1
REMARK 470 LYS A 452 CG CD CE NZ
REMARK 470 LYS A 455 CG CD CE NZ
REMARK 470 TYR A 456 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 MET A 483 CG SD CE
REMARK 470 MET A 555 CG SD CE
REMARK 470 ILE A 559 CG1 CG2 CD1
REMARK 470 LEU B 101 CG CD1 CD2
REMARK 470 ARG B 102 CG CD NE CZ NH1 NH2
REMARK 470 LEU B 105 CG CD1 CD2
REMARK 470 TYR B 107 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 ASP B 113 CG OD1 OD2
REMARK 470 LEU B 117 CG CD1 CD2
REMARK 470 MET B 121 CG SD CE
REMARK 470 GLU B 135 CG CD OE1 OE2
REMARK 470 ASP B 156 CG OD1 OD2
REMARK 470 ASP B 167 CG OD1 OD2
REMARK 470 GLU B 191 CG CD OE1 OE2
REMARK 470 GLU B 214 CG CD OE1 OE2
REMARK 470 ARG B 278 CG CD NE CZ NH1 NH2
REMARK 470 LEU B 292 CG CD1 CD2
REMARK 470 PHE B 315 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 ARG B 343 CG CD NE CZ NH1 NH2
REMARK 470 GLU B 369 CG CD OE1 OE2
REMARK 470 GLU B 370 CG CD OE1 OE2
REMARK 470 GLU B 373 CG CD OE1 OE2
REMARK 470 HIS B 375 CG ND1 CD2 CE1 NE2
REMARK 470 TYR B 381 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 ILE B 385 CG1 CG2 CD1
REMARK 470 ASN B 387 CG OD1 ND2
REMARK 470 LEU B 391 CG CD1 CD2
REMARK 470 GLU B 429 CG CD OE1 OE2
REMARK 470 MET B 441 CG SD CE
REMARK 470 ILE B 451 CG1 CG2 CD1
REMARK 470 LYS B 452 CG CD CE NZ
REMARK 470 LYS B 455 CG CD CE NZ
REMARK 470 TYR B 456 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 MET B 483 CG SD CE
REMARK 470 MET B 555 CG SD CE
REMARK 470 ILE B 559 CG1 CG2 CD1
REMARK 470 LEU C 101 CG CD1 CD2
REMARK 470 ARG C 102 CG CD NE CZ NH1 NH2
REMARK 470 LEU C 105 CG CD1 CD2
REMARK 470 TYR C 107 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 ASP C 113 CG OD1 OD2
REMARK 470 LEU C 117 CG CD1 CD2
REMARK 470 MET C 121 CG SD CE
REMARK 470 GLU C 135 CG CD OE1 OE2
REMARK 470 ASP C 156 CG OD1 OD2
REMARK 470 ASP C 167 CG OD1 OD2
REMARK 470 GLU C 191 CG CD OE1 OE2
REMARK 470 GLU C 214 CG CD OE1 OE2
REMARK 470 ARG C 278 CG CD NE CZ NH1 NH2
REMARK 470 LEU C 292 CG CD1 CD2
REMARK 470 PHE C 315 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 ARG C 343 CG CD NE CZ NH1 NH2
REMARK 470 GLU C 369 CG CD OE1 OE2
REMARK 470 GLU C 370 CG CD OE1 OE2
REMARK 470 GLU C 373 CG CD OE1 OE2
REMARK 470 HIS C 375 CG ND1 CD2 CE1 NE2
REMARK 470 TYR C 381 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 ILE C 385 CG1 CG2 CD1
REMARK 470 ASN C 387 CG OD1 ND2
REMARK 470 LEU C 391 CG CD1 CD2
REMARK 470 GLU C 429 CG CD OE1 OE2
REMARK 470 MET C 441 CG SD CE
REMARK 470 ILE C 451 CG1 CG2 CD1
REMARK 470 LYS C 452 CG CD CE NZ
REMARK 470 LYS C 455 CG CD CE NZ
REMARK 470 TYR C 456 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 MET C 483 CG SD CE
REMARK 470 MET C 555 CG SD CE
REMARK 470 ILE C 559 CG1 CG2 CD1
REMARK 470 LEU D 101 CG CD1 CD2
REMARK 470 ARG D 102 CG CD NE CZ NH1 NH2
REMARK 470 LEU D 105 CG CD1 CD2
REMARK 470 TYR D 107 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 ASP D 113 CG OD1 OD2
REMARK 470 LEU D 117 CG CD1 CD2
REMARK 470 MET D 121 CG SD CE
REMARK 470 GLU D 135 CG CD OE1 OE2
REMARK 470 ASP D 156 CG OD1 OD2
REMARK 470 ASP D 167 CG OD1 OD2
REMARK 470 GLU D 191 CG CD OE1 OE2
REMARK 470 GLU D 214 CG CD OE1 OE2
REMARK 470 ARG D 278 CG CD NE CZ NH1 NH2
REMARK 470 LEU D 292 CG CD1 CD2
REMARK 470 PHE D 315 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 ARG D 343 CG CD NE CZ NH1 NH2
REMARK 470 GLU D 369 CG CD OE1 OE2
REMARK 470 GLU D 370 CG CD OE1 OE2
REMARK 470 GLU D 373 CG CD OE1 OE2
REMARK 470 HIS D 375 CG ND1 CD2 CE1 NE2
REMARK 470 TYR D 381 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 ILE D 385 CG1 CG2 CD1
REMARK 470 ASN D 387 CG OD1 ND2
REMARK 470 LEU D 391 CG CD1 CD2
REMARK 470 GLU D 429 CG CD OE1 OE2
REMARK 470 MET D 441 CG SD CE
REMARK 470 ILE D 451 CG1 CG2 CD1
REMARK 470 LYS D 452 CG CD CE NZ
REMARK 470 LYS D 455 CG CD CE NZ
REMARK 470 TYR D 456 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 MET D 483 CG SD CE
REMARK 470 MET D 555 CG SD CE
REMARK 470 ILE D 559 CG1 CG2 CD1
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT
REMARK 500
REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT.
REMARK 500
REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI DISTANCE
REMARK 500 CB PHE A 315 CD2 LEU A 341 2.05
REMARK 500 CB PHE C 315 CD2 LEU C 341 2.05
REMARK 500 CB PHE B 315 CD2 LEU B 341 2.05
REMARK 500 CB PHE D 315 CD2 LEU D 341 2.05
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES
REMARK 500
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)
REMARK 500
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996
REMARK 500
REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3
REMARK 500 LEU A 318 CA - CB - CG ANGL. DEV. = 14.7 DEGREES
REMARK 500 LEU B 318 CA - CB - CG ANGL. DEV. = 14.7 DEGREES
REMARK 500 LEU C 318 CA - CB - CG ANGL. DEV. = 14.7 DEGREES
REMARK 500 LEU D 318 CA - CB - CG ANGL. DEV. = 14.7 DEGREES
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: TORSION ANGLES
REMARK 500
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)
REMARK 500
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400
REMARK 500
REMARK 500 M RES CSSEQI PSI PHI
REMARK 500 SER A 184 24.30 -140.11
REMARK 500 SER A 186 66.05 60.10
REMARK 500 TYR A 190 8.24 84.60
REMARK 500 GLU A 218 -12.42 68.86
REMARK 500 THR A 243 -26.66 76.86
REMARK 500 LEU A 341 -44.85 76.35
REMARK 500 GLN A 421 71.49 51.50
REMARK 500 THR A 501 -169.32 -74.66
REMARK 500 GLN A 502 -7.44 71.91
REMARK 500 ARG A 534 -4.82 74.07
REMARK 500 SER B 184 24.30 -140.11
REMARK 500 SER B 186 66.05 60.10
REMARK 500 TYR B 190 8.24 84.60
REMARK 500 GLU B 218 -12.42 68.86
REMARK 500 THR B 243 -26.66 76.86
REMARK 500 LEU B 341 -44.85 76.35
REMARK 500 GLN B 421 71.49 51.50
REMARK 500 THR B 501 -169.32 -74.66
REMARK 500 GLN B 502 -7.44 71.91
REMARK 500 ARG B 534 -4.82 74.07
REMARK 500 SER C 184 24.30 -140.11
REMARK 500 SER C 186 66.05 60.10
REMARK 500 TYR C 190 8.24 84.60
REMARK 500 GLU C 218 -12.42 68.86
REMARK 500 THR C 243 -26.66 76.86
REMARK 500 LEU C 341 -44.85 76.35
REMARK 500 GLN C 421 71.49 51.50
REMARK 500 THR C 501 -169.32 -74.66
REMARK 500 GLN C 502 -7.44 71.91
REMARK 500 ARG C 534 -4.82 74.07
REMARK 500 SER D 184 24.30 -140.11
REMARK 500 SER D 186 66.05 60.10
REMARK 500 TYR D 190 8.24 84.60
REMARK 500 GLU D 218 -12.42 68.86
REMARK 500 THR D 243 -26.66 76.86
REMARK 500 LEU D 341 -44.85 76.35
REMARK 500 GLN D 421 71.49 51.50
REMARK 500 THR D 501 -169.32 -74.66
REMARK 500 GLN D 502 -7.44 71.91
REMARK 500 ARG D 534 -4.82 74.07
REMARK 500
REMARK 500 REMARK: NULL
REMARK 900
REMARK 900 RELATED ENTRIES
REMARK 900 RELATED ID: EMD-8912 RELATED DB: EMDB
REMARK 900 HUMAN POLYCSYTIN 2-L1
DBREF 6DU8 A 1 805 UNP Q9P0L9 PK2L1_HUMAN 1 805
DBREF 6DU8 B 1 805 UNP Q9P0L9 PK2L1_HUMAN 1 805
DBREF 6DU8 C 1 805 UNP Q9P0L9 PK2L1_HUMAN 1 805
DBREF 6DU8 D 1 805 UNP Q9P0L9 PK2L1_HUMAN 1 805
SEQRES 1 A 805 MET ASN ALA VAL GLY SER PRO GLU GLY GLN GLU LEU GLN
SEQRES 2 A 805 LYS LEU GLY SER GLY ALA TRP ASP ASN PRO ALA TYR SER
SEQRES 3 A 805 GLY PRO PRO SER PRO HIS GLY THR LEU ARG VAL CYS THR
SEQRES 4 A 805 ILE SER SER THR GLY PRO LEU GLN PRO GLN PRO LYS LYS
SEQRES 5 A 805 PRO GLU ASP GLU PRO GLN GLU THR ALA TYR ARG THR GLN
SEQRES 6 A 805 VAL SER SER CYS CYS LEU HIS ILE CYS GLN GLY ILE ARG
SEQRES 7 A 805 GLY LEU TRP GLY THR THR LEU THR GLU ASN THR ALA GLU
SEQRES 8 A 805 ASN ARG GLU LEU TYR ILE LYS THR THR LEU ARG GLU LEU
SEQRES 9 A 805 LEU VAL TYR ILE VAL PHE LEU VAL ASP ILE CYS LEU LEU
SEQRES 10 A 805 THR TYR GLY MET THR SER SER SER ALA TYR TYR TYR THR
SEQRES 11 A 805 LYS VAL MET SER GLU LEU PHE LEU HIS THR PRO SER ASP
SEQRES 12 A 805 THR GLY VAL SER PHE GLN ALA ILE SER SER MET ALA ASP
SEQRES 13 A 805 PHE TRP ASP PHE ALA GLN GLY PRO LEU LEU ASP SER LEU
SEQRES 14 A 805 TYR TRP THR LYS TRP TYR ASN ASN GLN SER LEU GLY HIS
SEQRES 15 A 805 GLY SER HIS SER PHE ILE TYR TYR GLU ASN MET LEU LEU
SEQRES 16 A 805 GLY VAL PRO ARG LEU ARG GLN LEU LYS VAL ARG ASN ASP
SEQRES 17 A 805 SER CYS VAL VAL HIS GLU ASP PHE ARG GLU ASP ILE LEU
SEQRES 18 A 805 SER CYS TYR ASP VAL TYR SER PRO ASP LYS GLU GLU GLN
SEQRES 19 A 805 LEU PRO PHE GLY PRO PHE ASN GLY THR ALA TRP THR TYR
SEQRES 20 A 805 HIS SER GLN ASP GLU LEU GLY GLY PHE SER HIS TRP GLY
SEQRES 21 A 805 ARG LEU THR SER TYR SER GLY GLY GLY TYR TYR LEU ASP
SEQRES 22 A 805 LEU PRO GLY SER ARG GLN GLY SER ALA GLU ALA LEU ARG
SEQRES 23 A 805 ALA LEU GLN GLU GLY LEU TRP LEU ASP ARG GLY THR ARG
SEQRES 24 A 805 VAL VAL PHE ILE ASP PHE SER VAL TYR ASN ALA ASN ILE
SEQRES 25 A 805 ASN LEU PHE CYS VAL LEU ARG LEU VAL VAL GLU PHE PRO
SEQRES 26 A 805 ALA THR GLY GLY ALA ILE PRO SER TRP GLN ILE ARG THR
SEQRES 27 A 805 VAL LYS LEU ILE ARG TYR VAL SER ASN TRP ASP PHE PHE
SEQRES 28 A 805 ILE VAL GLY CYS GLU VAL ILE PHE CYS VAL PHE ILE PHE
SEQRES 29 A 805 TYR TYR VAL VAL GLU GLU ILE LEU GLU LEU HIS ILE HIS
SEQRES 30 A 805 ARG LEU ARG TYR LEU SER SER ILE TRP ASN ILE LEU ASP
SEQRES 31 A 805 LEU VAL VAL ILE LEU LEU SER ILE VAL ALA VAL GLY PHE
SEQRES 32 A 805 HIS ILE PHE ARG THR LEU GLU VAL ASN ARG LEU MET GLY
SEQRES 33 A 805 LYS LEU LEU GLN GLN PRO ASN THR TYR ALA ASP PHE GLU
SEQRES 34 A 805 PHE LEU ALA PHE TRP GLN THR GLN TYR ASN ASN MET ASN
SEQRES 35 A 805 ALA VAL ASN LEU PHE PHE ALA TRP ILE LYS ILE PHE LYS
SEQRES 36 A 805 TYR ILE SER PHE ASN LYS THR MET THR GLN LEU SER SER
SEQRES 37 A 805 THR LEU ALA ARG CYS ALA LYS ASP ILE LEU GLY PHE ALA
SEQRES 38 A 805 VAL MET PHE PHE ILE VAL PHE PHE ALA TYR ALA GLN LEU
SEQRES 39 A 805 GLY TYR LEU LEU PHE GLY THR GLN VAL GLU ASN PHE SER
SEQRES 40 A 805 THR PHE ILE LYS CYS ILE PHE THR GLN PHE ARG ILE ILE
SEQRES 41 A 805 LEU GLY ASP PHE ASP TYR ASN ALA ILE ASP ASN ALA ASN
SEQRES 42 A 805 ARG ILE LEU GLY PRO ALA TYR PHE VAL THR TYR VAL PHE
SEQRES 43 A 805 PHE VAL PHE PHE VAL LEU LEU ASN MET PHE LEU ALA ILE
SEQRES 44 A 805 ILE ASN ASP THR TYR SER GLU VAL LYS GLU GLU LEU ALA
SEQRES 45 A 805 GLY GLN LYS ASP GLU LEU GLN LEU SER ASP LEU LEU LYS
SEQRES 46 A 805 GLN GLY TYR ASN LYS THR LEU LEU ARG LEU ARG LEU ARG
SEQRES 47 A 805 LYS GLU ARG VAL SER ASP VAL GLN LYS VAL LEU GLN GLY
SEQRES 48 A 805 GLY GLU GLN GLU ILE GLN PHE GLU ASP PHE THR ASN THR
SEQRES 49 A 805 LEU ARG GLU LEU GLY HIS ALA GLU HIS GLU ILE THR GLU
SEQRES 50 A 805 LEU THR ALA THR PHE THR LYS PHE ASP ARG ASP GLY ASN
SEQRES 51 A 805 ARG ILE LEU ASP GLU LYS GLU GLN GLU LYS MET ARG GLN
SEQRES 52 A 805 ASP LEU GLU GLU GLU ARG VAL ALA LEU ASN THR GLU ILE
SEQRES 53 A 805 GLU LYS LEU GLY ARG SER ILE VAL SER SER PRO GLN GLY
SEQRES 54 A 805 LYS SER GLY PRO GLU ALA ALA ARG ALA GLY GLY TRP VAL
SEQRES 55 A 805 SER GLY GLU GLU PHE TYR MET LEU THR ARG ARG VAL LEU
SEQRES 56 A 805 GLN LEU GLU THR VAL LEU GLU GLY VAL VAL SER GLN ILE
SEQRES 57 A 805 ASP ALA VAL GLY SER LYS LEU LYS MET LEU GLU ARG LYS
SEQRES 58 A 805 GLY TRP LEU ALA PRO SER PRO GLY VAL LYS GLU GLN ALA
SEQRES 59 A 805 ILE TRP LYS HIS PRO GLN PRO ALA PRO ALA VAL THR PRO
SEQRES 60 A 805 ASP PRO TRP GLY VAL GLN GLY GLY GLN GLU SER GLU VAL
SEQRES 61 A 805 PRO TYR LYS ARG GLU GLU GLU ALA LEU GLU GLU ARG ARG
SEQRES 62 A 805 LEU SER ARG GLY GLU ILE PRO THR LEU GLN ARG SER
SEQRES 1 B 805 MET ASN ALA VAL GLY SER PRO GLU GLY GLN GLU LEU GLN
SEQRES 2 B 805 LYS LEU GLY SER GLY ALA TRP ASP ASN PRO ALA TYR SER
SEQRES 3 B 805 GLY PRO PRO SER PRO HIS GLY THR LEU ARG VAL CYS THR
SEQRES 4 B 805 ILE SER SER THR GLY PRO LEU GLN PRO GLN PRO LYS LYS
SEQRES 5 B 805 PRO GLU ASP GLU PRO GLN GLU THR ALA TYR ARG THR GLN
SEQRES 6 B 805 VAL SER SER CYS CYS LEU HIS ILE CYS GLN GLY ILE ARG
SEQRES 7 B 805 GLY LEU TRP GLY THR THR LEU THR GLU ASN THR ALA GLU
SEQRES 8 B 805 ASN ARG GLU LEU TYR ILE LYS THR THR LEU ARG GLU LEU
SEQRES 9 B 805 LEU VAL TYR ILE VAL PHE LEU VAL ASP ILE CYS LEU LEU
SEQRES 10 B 805 THR TYR GLY MET THR SER SER SER ALA TYR TYR TYR THR
SEQRES 11 B 805 LYS VAL MET SER GLU LEU PHE LEU HIS THR PRO SER ASP
SEQRES 12 B 805 THR GLY VAL SER PHE GLN ALA ILE SER SER MET ALA ASP
SEQRES 13 B 805 PHE TRP ASP PHE ALA GLN GLY PRO LEU LEU ASP SER LEU
SEQRES 14 B 805 TYR TRP THR LYS TRP TYR ASN ASN GLN SER LEU GLY HIS
SEQRES 15 B 805 GLY SER HIS SER PHE ILE TYR TYR GLU ASN MET LEU LEU
SEQRES 16 B 805 GLY VAL PRO ARG LEU ARG GLN LEU LYS VAL ARG ASN ASP
SEQRES 17 B 805 SER CYS VAL VAL HIS GLU ASP PHE ARG GLU ASP ILE LEU
SEQRES 18 B 805 SER CYS TYR ASP VAL TYR SER PRO ASP LYS GLU GLU GLN
SEQRES 19 B 805 LEU PRO PHE GLY PRO PHE ASN GLY THR ALA TRP THR TYR
SEQRES 20 B 805 HIS SER GLN ASP GLU LEU GLY GLY PHE SER HIS TRP GLY
SEQRES 21 B 805 ARG LEU THR SER TYR SER GLY GLY GLY TYR TYR LEU ASP
SEQRES 22 B 805 LEU PRO GLY SER ARG GLN GLY SER ALA GLU ALA LEU ARG
SEQRES 23 B 805 ALA LEU GLN GLU GLY LEU TRP LEU ASP ARG GLY THR ARG
SEQRES 24 B 805 VAL VAL PHE ILE ASP PHE SER VAL TYR ASN ALA ASN ILE
SEQRES 25 B 805 ASN LEU PHE CYS VAL LEU ARG LEU VAL VAL GLU PHE PRO
SEQRES 26 B 805 ALA THR GLY GLY ALA ILE PRO SER TRP GLN ILE ARG THR
SEQRES 27 B 805 VAL LYS LEU ILE ARG TYR VAL SER ASN TRP ASP PHE PHE
SEQRES 28 B 805 ILE VAL GLY CYS GLU VAL ILE PHE CYS VAL PHE ILE PHE
SEQRES 29 B 805 TYR TYR VAL VAL GLU GLU ILE LEU GLU LEU HIS ILE HIS
SEQRES 30 B 805 ARG LEU ARG TYR LEU SER SER ILE TRP ASN ILE LEU ASP
SEQRES 31 B 805 LEU VAL VAL ILE LEU LEU SER ILE VAL ALA VAL GLY PHE
SEQRES 32 B 805 HIS ILE PHE ARG THR LEU GLU VAL ASN ARG LEU MET GLY
SEQRES 33 B 805 LYS LEU LEU GLN GLN PRO ASN THR TYR ALA ASP PHE GLU
SEQRES 34 B 805 PHE LEU ALA PHE TRP GLN THR GLN TYR ASN ASN MET ASN
SEQRES 35 B 805 ALA VAL ASN LEU PHE PHE ALA TRP ILE LYS ILE PHE LYS
SEQRES 36 B 805 TYR ILE SER PHE ASN LYS THR MET THR GLN LEU SER SER
SEQRES 37 B 805 THR LEU ALA ARG CYS ALA LYS ASP ILE LEU GLY PHE ALA
SEQRES 38 B 805 VAL MET PHE PHE ILE VAL PHE PHE ALA TYR ALA GLN LEU
SEQRES 39 B 805 GLY TYR LEU LEU PHE GLY THR GLN VAL GLU ASN PHE SER
SEQRES 40 B 805 THR PHE ILE LYS CYS ILE PHE THR GLN PHE ARG ILE ILE
SEQRES 41 B 805 LEU GLY ASP PHE ASP TYR ASN ALA ILE ASP ASN ALA ASN
SEQRES 42 B 805 ARG ILE LEU GLY PRO ALA TYR PHE VAL THR TYR VAL PHE
SEQRES 43 B 805 PHE VAL PHE PHE VAL LEU LEU ASN MET PHE LEU ALA ILE
SEQRES 44 B 805 ILE ASN ASP THR TYR SER GLU VAL LYS GLU GLU LEU ALA
SEQRES 45 B 805 GLY GLN LYS ASP GLU LEU GLN LEU SER ASP LEU LEU LYS
SEQRES 46 B 805 GLN GLY TYR ASN LYS THR LEU LEU ARG LEU ARG LEU ARG
SEQRES 47 B 805 LYS GLU ARG VAL SER ASP VAL GLN LYS VAL LEU GLN GLY
SEQRES 48 B 805 GLY GLU GLN GLU ILE GLN PHE GLU ASP PHE THR ASN THR
SEQRES 49 B 805 LEU ARG GLU LEU GLY HIS ALA GLU HIS GLU ILE THR GLU
SEQRES 50 B 805 LEU THR ALA THR PHE THR LYS PHE ASP ARG ASP GLY ASN
SEQRES 51 B 805 ARG ILE LEU ASP GLU LYS GLU GLN GLU LYS MET ARG GLN
SEQRES 52 B 805 ASP LEU GLU GLU GLU ARG VAL ALA LEU ASN THR GLU ILE
SEQRES 53 B 805 GLU LYS LEU GLY ARG SER ILE VAL SER SER PRO GLN GLY
SEQRES 54 B 805 LYS SER GLY PRO GLU ALA ALA ARG ALA GLY GLY TRP VAL
SEQRES 55 B 805 SER GLY GLU GLU PHE TYR MET LEU THR ARG ARG VAL LEU
SEQRES 56 B 805 GLN LEU GLU THR VAL LEU GLU GLY VAL VAL SER GLN ILE
SEQRES 57 B 805 ASP ALA VAL GLY SER LYS LEU LYS MET LEU GLU ARG LYS
SEQRES 58 B 805 GLY TRP LEU ALA PRO SER PRO GLY VAL LYS GLU GLN ALA
SEQRES 59 B 805 ILE TRP LYS HIS PRO GLN PRO ALA PRO ALA VAL THR PRO
SEQRES 60 B 805 ASP PRO TRP GLY VAL GLN GLY GLY GLN GLU SER GLU VAL
SEQRES 61 B 805 PRO TYR LYS ARG GLU GLU GLU ALA LEU GLU GLU ARG ARG
SEQRES 62 B 805 LEU SER ARG GLY GLU ILE PRO THR LEU GLN ARG SER
SEQRES 1 C 805 MET ASN ALA VAL GLY SER PRO GLU GLY GLN GLU LEU GLN
SEQRES 2 C 805 LYS LEU GLY SER GLY ALA TRP ASP ASN PRO ALA TYR SER
SEQRES 3 C 805 GLY PRO PRO SER PRO HIS GLY THR LEU ARG VAL CYS THR
SEQRES 4 C 805 ILE SER SER THR GLY PRO LEU GLN PRO GLN PRO LYS LYS
SEQRES 5 C 805 PRO GLU ASP GLU PRO GLN GLU THR ALA TYR ARG THR GLN
SEQRES 6 C 805 VAL SER SER CYS CYS LEU HIS ILE CYS GLN GLY ILE ARG
SEQRES 7 C 805 GLY LEU TRP GLY THR THR LEU THR GLU ASN THR ALA GLU
SEQRES 8 C 805 ASN ARG GLU LEU TYR ILE LYS THR THR LEU ARG GLU LEU
SEQRES 9 C 805 LEU VAL TYR ILE VAL PHE LEU VAL ASP ILE CYS LEU LEU
SEQRES 10 C 805 THR TYR GLY MET THR SER SER SER ALA TYR TYR TYR THR
SEQRES 11 C 805 LYS VAL MET SER GLU LEU PHE LEU HIS THR PRO SER ASP
SEQRES 12 C 805 THR GLY VAL SER PHE GLN ALA ILE SER SER MET ALA ASP
SEQRES 13 C 805 PHE TRP ASP PHE ALA GLN GLY PRO LEU LEU ASP SER LEU
SEQRES 14 C 805 TYR TRP THR LYS TRP TYR ASN ASN GLN SER LEU GLY HIS
SEQRES 15 C 805 GLY SER HIS SER PHE ILE TYR TYR GLU ASN MET LEU LEU
SEQRES 16 C 805 GLY VAL PRO ARG LEU ARG GLN LEU LYS VAL ARG ASN ASP
SEQRES 17 C 805 SER CYS VAL VAL HIS GLU ASP PHE ARG GLU ASP ILE LEU
SEQRES 18 C 805 SER CYS TYR ASP VAL TYR SER PRO ASP LYS GLU GLU GLN
SEQRES 19 C 805 LEU PRO PHE GLY PRO PHE ASN GLY THR ALA TRP THR TYR
SEQRES 20 C 805 HIS SER GLN ASP GLU LEU GLY GLY PHE SER HIS TRP GLY
SEQRES 21 C 805 ARG LEU THR SER TYR SER GLY GLY GLY TYR TYR LEU ASP
SEQRES 22 C 805 LEU PRO GLY SER ARG GLN GLY SER ALA GLU ALA LEU ARG
SEQRES 23 C 805 ALA LEU GLN GLU GLY LEU TRP LEU ASP ARG GLY THR ARG
SEQRES 24 C 805 VAL VAL PHE ILE ASP PHE SER VAL TYR ASN ALA ASN ILE
SEQRES 25 C 805 ASN LEU PHE CYS VAL LEU ARG LEU VAL VAL GLU PHE PRO
SEQRES 26 C 805 ALA THR GLY GLY ALA ILE PRO SER TRP GLN ILE ARG THR
SEQRES 27 C 805 VAL LYS LEU ILE ARG TYR VAL SER ASN TRP ASP PHE PHE
SEQRES 28 C 805 ILE VAL GLY CYS GLU VAL ILE PHE CYS VAL PHE ILE PHE
SEQRES 29 C 805 TYR TYR VAL VAL GLU GLU ILE LEU GLU LEU HIS ILE HIS
SEQRES 30 C 805 ARG LEU ARG TYR LEU SER SER ILE TRP ASN ILE LEU ASP
SEQRES 31 C 805 LEU VAL VAL ILE LEU LEU SER ILE VAL ALA VAL GLY PHE
SEQRES 32 C 805 HIS ILE PHE ARG THR LEU GLU VAL ASN ARG LEU MET GLY
SEQRES 33 C 805 LYS LEU LEU GLN GLN PRO ASN THR TYR ALA ASP PHE GLU
SEQRES 34 C 805 PHE LEU ALA PHE TRP GLN THR GLN TYR ASN ASN MET ASN
SEQRES 35 C 805 ALA VAL ASN LEU PHE PHE ALA TRP ILE LYS ILE PHE LYS
SEQRES 36 C 805 TYR ILE SER PHE ASN LYS THR MET THR GLN LEU SER SER
SEQRES 37 C 805 THR LEU ALA ARG CYS ALA LYS ASP ILE LEU GLY PHE ALA
SEQRES 38 C 805 VAL MET PHE PHE ILE VAL PHE PHE ALA TYR ALA GLN LEU
SEQRES 39 C 805 GLY TYR LEU LEU PHE GLY THR GLN VAL GLU ASN PHE SER
SEQRES 40 C 805 THR PHE ILE LYS CYS ILE PHE THR GLN PHE ARG ILE ILE
SEQRES 41 C 805 LEU GLY ASP PHE ASP TYR ASN ALA ILE ASP ASN ALA ASN
SEQRES 42 C 805 ARG ILE LEU GLY PRO ALA TYR PHE VAL THR TYR VAL PHE
SEQRES 43 C 805 PHE VAL PHE PHE VAL LEU LEU ASN MET PHE LEU ALA ILE
SEQRES 44 C 805 ILE ASN ASP THR TYR SER GLU VAL LYS GLU GLU LEU ALA
SEQRES 45 C 805 GLY GLN LYS ASP GLU LEU GLN LEU SER ASP LEU LEU LYS
SEQRES 46 C 805 GLN GLY TYR ASN LYS THR LEU LEU ARG LEU ARG LEU ARG
SEQRES 47 C 805 LYS GLU ARG VAL SER ASP VAL GLN LYS VAL LEU GLN GLY
SEQRES 48 C 805 GLY GLU GLN GLU ILE GLN PHE GLU ASP PHE THR ASN THR
SEQRES 49 C 805 LEU ARG GLU LEU GLY HIS ALA GLU HIS GLU ILE THR GLU
SEQRES 50 C 805 LEU THR ALA THR PHE THR LYS PHE ASP ARG ASP GLY ASN
SEQRES 51 C 805 ARG ILE LEU ASP GLU LYS GLU GLN GLU LYS MET ARG GLN
SEQRES 52 C 805 ASP LEU GLU GLU GLU ARG VAL ALA LEU ASN THR GLU ILE
SEQRES 53 C 805 GLU LYS LEU GLY ARG SER ILE VAL SER SER PRO GLN GLY
SEQRES 54 C 805 LYS SER GLY PRO GLU ALA ALA ARG ALA GLY GLY TRP VAL
SEQRES 55 C 805 SER GLY GLU GLU PHE TYR MET LEU THR ARG ARG VAL LEU
SEQRES 56 C 805 GLN LEU GLU THR VAL LEU GLU GLY VAL VAL SER GLN ILE
SEQRES 57 C 805 ASP ALA VAL GLY SER LYS LEU LYS MET LEU GLU ARG LYS
SEQRES 58 C 805 GLY TRP LEU ALA PRO SER PRO GLY VAL LYS GLU GLN ALA
SEQRES 59 C 805 ILE TRP LYS HIS PRO GLN PRO ALA PRO ALA VAL THR PRO
SEQRES 60 C 805 ASP PRO TRP GLY VAL GLN GLY GLY GLN GLU SER GLU VAL
SEQRES 61 C 805 PRO TYR LYS ARG GLU GLU GLU ALA LEU GLU GLU ARG ARG
SEQRES 62 C 805 LEU SER ARG GLY GLU ILE PRO THR LEU GLN ARG SER
SEQRES 1 D 805 MET ASN ALA VAL GLY SER PRO GLU GLY GLN GLU LEU GLN
SEQRES 2 D 805 LYS LEU GLY SER GLY ALA TRP ASP ASN PRO ALA TYR SER
SEQRES 3 D 805 GLY PRO PRO SER PRO HIS GLY THR LEU ARG VAL CYS THR
SEQRES 4 D 805 ILE SER SER THR GLY PRO LEU GLN PRO GLN PRO LYS LYS
SEQRES 5 D 805 PRO GLU ASP GLU PRO GLN GLU THR ALA TYR ARG THR GLN
SEQRES 6 D 805 VAL SER SER CYS CYS LEU HIS ILE CYS GLN GLY ILE ARG
SEQRES 7 D 805 GLY LEU TRP GLY THR THR LEU THR GLU ASN THR ALA GLU
SEQRES 8 D 805 ASN ARG GLU LEU TYR ILE LYS THR THR LEU ARG GLU LEU
SEQRES 9 D 805 LEU VAL TYR ILE VAL PHE LEU VAL ASP ILE CYS LEU LEU
SEQRES 10 D 805 THR TYR GLY MET THR SER SER SER ALA TYR TYR TYR THR
SEQRES 11 D 805 LYS VAL MET SER GLU LEU PHE LEU HIS THR PRO SER ASP
SEQRES 12 D 805 THR GLY VAL SER PHE GLN ALA ILE SER SER MET ALA ASP
SEQRES 13 D 805 PHE TRP ASP PHE ALA GLN GLY PRO LEU LEU ASP SER LEU
SEQRES 14 D 805 TYR TRP THR LYS TRP TYR ASN ASN GLN SER LEU GLY HIS
SEQRES 15 D 805 GLY SER HIS SER PHE ILE TYR TYR GLU ASN MET LEU LEU
SEQRES 16 D 805 GLY VAL PRO ARG LEU ARG GLN LEU LYS VAL ARG ASN ASP
SEQRES 17 D 805 SER CYS VAL VAL HIS GLU ASP PHE ARG GLU ASP ILE LEU
SEQRES 18 D 805 SER CYS TYR ASP VAL TYR SER PRO ASP LYS GLU GLU GLN
SEQRES 19 D 805 LEU PRO PHE GLY PRO PHE ASN GLY THR ALA TRP THR TYR
SEQRES 20 D 805 HIS SER GLN ASP GLU LEU GLY GLY PHE SER HIS TRP GLY
SEQRES 21 D 805 ARG LEU THR SER TYR SER GLY GLY GLY TYR TYR LEU ASP
SEQRES 22 D 805 LEU PRO GLY SER ARG GLN GLY SER ALA GLU ALA LEU ARG
SEQRES 23 D 805 ALA LEU GLN GLU GLY LEU TRP LEU ASP ARG GLY THR ARG
SEQRES 24 D 805 VAL VAL PHE ILE ASP PHE SER VAL TYR ASN ALA ASN ILE
SEQRES 25 D 805 ASN LEU PHE CYS VAL LEU ARG LEU VAL VAL GLU PHE PRO
SEQRES 26 D 805 ALA THR GLY GLY ALA ILE PRO SER TRP GLN ILE ARG THR
SEQRES 27 D 805 VAL LYS LEU ILE ARG TYR VAL SER ASN TRP ASP PHE PHE
SEQRES 28 D 805 ILE VAL GLY CYS GLU VAL ILE PHE CYS VAL PHE ILE PHE
SEQRES 29 D 805 TYR TYR VAL VAL GLU GLU ILE LEU GLU LEU HIS ILE HIS
SEQRES 30 D 805 ARG LEU ARG TYR LEU SER SER ILE TRP ASN ILE LEU ASP
SEQRES 31 D 805 LEU VAL VAL ILE LEU LEU SER ILE VAL ALA VAL GLY PHE
SEQRES 32 D 805 HIS ILE PHE ARG THR LEU GLU VAL ASN ARG LEU MET GLY
SEQRES 33 D 805 LYS LEU LEU GLN GLN PRO ASN THR TYR ALA ASP PHE GLU
SEQRES 34 D 805 PHE LEU ALA PHE TRP GLN THR GLN TYR ASN ASN MET ASN
SEQRES 35 D 805 ALA VAL ASN LEU PHE PHE ALA TRP ILE LYS ILE PHE LYS
SEQRES 36 D 805 TYR ILE SER PHE ASN LYS THR MET THR GLN LEU SER SER
SEQRES 37 D 805 THR LEU ALA ARG CYS ALA LYS ASP ILE LEU GLY PHE ALA
SEQRES 38 D 805 VAL MET PHE PHE ILE VAL PHE PHE ALA TYR ALA GLN LEU
SEQRES 39 D 805 GLY TYR LEU LEU PHE GLY THR GLN VAL GLU ASN PHE SER
SEQRES 40 D 805 THR PHE ILE LYS CYS ILE PHE THR GLN PHE ARG ILE ILE
SEQRES 41 D 805 LEU GLY ASP PHE ASP TYR ASN ALA ILE ASP ASN ALA ASN
SEQRES 42 D 805 ARG ILE LEU GLY PRO ALA TYR PHE VAL THR TYR VAL PHE
SEQRES 43 D 805 PHE VAL PHE PHE VAL LEU LEU ASN MET PHE LEU ALA ILE
SEQRES 44 D 805 ILE ASN ASP THR TYR SER GLU VAL LYS GLU GLU LEU ALA
SEQRES 45 D 805 GLY GLN LYS ASP GLU LEU GLN LEU SER ASP LEU LEU LYS
SEQRES 46 D 805 GLN GLY TYR ASN LYS THR LEU LEU ARG LEU ARG LEU ARG
SEQRES 47 D 805 LYS GLU ARG VAL SER ASP VAL GLN LYS VAL LEU GLN GLY
SEQRES 48 D 805 GLY GLU GLN GLU ILE GLN PHE GLU ASP PHE THR ASN THR
SEQRES 49 D 805 LEU ARG GLU LEU GLY HIS ALA GLU HIS GLU ILE THR GLU
SEQRES 50 D 805 LEU THR ALA THR PHE THR LYS PHE ASP ARG ASP GLY ASN
SEQRES 51 D 805 ARG ILE LEU ASP GLU LYS GLU GLN GLU LYS MET ARG GLN
SEQRES 52 D 805 ASP LEU GLU GLU GLU ARG VAL ALA LEU ASN THR GLU ILE
SEQRES 53 D 805 GLU LYS LEU GLY ARG SER ILE VAL SER SER PRO GLN GLY
SEQRES 54 D 805 LYS SER GLY PRO GLU ALA ALA ARG ALA GLY GLY TRP VAL
SEQRES 55 D 805 SER GLY GLU GLU PHE TYR MET LEU THR ARG ARG VAL LEU
SEQRES 56 D 805 GLN LEU GLU THR VAL LEU GLU GLY VAL VAL SER GLN ILE
SEQRES 57 D 805 ASP ALA VAL GLY SER LYS LEU LYS MET LEU GLU ARG LYS
SEQRES 58 D 805 GLY TRP LEU ALA PRO SER PRO GLY VAL LYS GLU GLN ALA
SEQRES 59 D 805 ILE TRP LYS HIS PRO GLN PRO ALA PRO ALA VAL THR PRO
SEQRES 60 D 805 ASP PRO TRP GLY VAL GLN GLY GLY GLN GLU SER GLU VAL
SEQRES 61 D 805 PRO TYR LYS ARG GLU GLU GLU ALA LEU GLU GLU ARG ARG
SEQRES 62 D 805 LEU SER ARG GLY GLU ILE PRO THR LEU GLN ARG SER
HET NAG A 901 14
HET NAG B 901 14
HET NAG C 901 14
HET NAG D 901 14
HETNAM NAG 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE
FORMUL 5 NAG 4(C8 H15 N O6)
HELIX 1 AA1 LEU A 104 TYR A 119 1 16
HELIX 2 AA2 ALA A 126 LEU A 138 1 13
HELIX 3 AA3 SER A 147 ILE A 151 5 5
HELIX 4 AA4 ASP A 156 ALA A 161 1 6
HELIX 5 AA5 SER A 249 GLY A 254 1 6
HELIX 6 AA6 SER A 277 GLY A 291 1 15
HELIX 7 AA7 CYS A 355 ILE A 376 1 22
HELIX 8 AA8 ILE A 385 GLN A 420 1 36
HELIX 9 AA9 PHE A 428 LYS A 452 1 25
HELIX 10 AB1 ILE A 453 LYS A 455 5 3
HELIX 11 AB2 ALA A 481 PHE A 499 1 19
HELIX 12 AB3 ILE A 510 GLY A 522 1 13
HELIX 13 AB4 LEU A 536 ILE A 560 1 25
HELIX 14 AB5 LEU B 104 TYR B 119 1 16
HELIX 15 AB6 ALA B 126 LEU B 138 1 13
HELIX 16 AB7 SER B 147 ILE B 151 5 5
HELIX 17 AB8 ASP B 156 ALA B 161 1 6
HELIX 18 AB9 SER B 249 GLY B 254 1 6
HELIX 19 AC1 SER B 277 GLY B 291 1 15
HELIX 20 AC2 CYS B 355 ILE B 376 1 22
HELIX 21 AC3 ILE B 385 GLN B 420 1 36
HELIX 22 AC4 PHE B 428 LYS B 452 1 25
HELIX 23 AC5 ILE B 453 LYS B 455 5 3
HELIX 24 AC6 ALA B 481 PHE B 499 1 19
HELIX 25 AC7 ILE B 510 GLY B 522 1 13
HELIX 26 AC8 LEU B 536 ILE B 560 1 25
HELIX 27 AC9 LEU C 104 TYR C 119 1 16
HELIX 28 AD1 ALA C 126 LEU C 138 1 13
HELIX 29 AD2 SER C 147 ILE C 151 5 5
HELIX 30 AD3 ASP C 156 ALA C 161 1 6
HELIX 31 AD4 SER C 249 GLY C 254 1 6
HELIX 32 AD5 SER C 277 GLY C 291 1 15
HELIX 33 AD6 CYS C 355 ILE C 376 1 22
HELIX 34 AD7 ILE C 385 GLN C 420 1 36
HELIX 35 AD8 PHE C 428 LYS C 452 1 25
HELIX 36 AD9 ILE C 453 LYS C 455 5 3
HELIX 37 AE1 ALA C 481 PHE C 499 1 19
HELIX 38 AE2 ILE C 510 GLY C 522 1 13
HELIX 39 AE3 LEU C 536 ILE C 560 1 25
HELIX 40 AE4 LEU D 104 TYR D 119 1 16
HELIX 41 AE5 ALA D 126 LEU D 138 1 13
HELIX 42 AE6 SER D 147 ILE D 151 5 5
HELIX 43 AE7 ASP D 156 ALA D 161 1 6
HELIX 44 AE8 SER D 249 GLY D 254 1 6
HELIX 45 AE9 SER D 277 GLY D 291 1 15
HELIX 46 AF1 CYS D 355 ILE D 376 1 22
HELIX 47 AF2 ILE D 385 GLN D 420 1 36
HELIX 48 AF3 PHE D 428 LYS D 452 1 25
HELIX 49 AF4 ILE D 453 LYS D 455 5 3
HELIX 50 AF5 ALA D 481 PHE D 499 1 19
HELIX 51 AF6 ILE D 510 GLY D 522 1 13
HELIX 52 AF7 LEU D 536 ILE D 560 1 25
SHEET 1 AA1 3 MET A 193 LEU A 194 0
SHEET 2 AA1 3 THR A 298 ASN A 309 -1 O TYR A 308 N MET A 193
SHEET 3 AA1 3 GLN A 202 LYS A 204 -1 N LEU A 203 O VAL A 300
SHEET 1 AA2 4 MET A 193 LEU A 194 0
SHEET 2 AA2 4 THR A 298 ASN A 309 -1 O TYR A 308 N MET A 193
SHEET 3 AA2 4 LEU A 314 GLU A 323 -1 O LEU A 318 N PHE A 305
SHEET 4 AA2 4 SER A 333 VAL A 339 -1 O ARG A 337 N VAL A 317
SHEET 1 AA3 3 MET B 193 LEU B 194 0
SHEET 2 AA3 3 THR B 298 ASN B 309 -1 O TYR B 308 N MET B 193
SHEET 3 AA3 3 GLN B 202 LYS B 204 -1 N LEU B 203 O VAL B 300
SHEET 1 AA4 4 MET B 193 LEU B 194 0
SHEET 2 AA4 4 THR B 298 ASN B 309 -1 O TYR B 308 N MET B 193
SHEET 3 AA4 4 LEU B 314 GLU B 323 -1 O LEU B 318 N PHE B 305
SHEET 4 AA4 4 SER B 333 VAL B 339 -1 O ARG B 337 N VAL B 317
SHEET 1 AA5 3 MET C 193 LEU C 194 0
SHEET 2 AA5 3 THR C 298 ASN C 309 -1 O TYR C 308 N MET C 193
SHEET 3 AA5 3 GLN C 202 LYS C 204 -1 N LEU C 203 O VAL C 300
SHEET 1 AA6 4 MET C 193 LEU C 194 0
SHEET 2 AA6 4 THR C 298 ASN C 309 -1 O TYR C 308 N MET C 193
SHEET 3 AA6 4 LEU C 314 GLU C 323 -1 O LEU C 318 N PHE C 305
SHEET 4 AA6 4 SER C 333 VAL C 339 -1 O ARG C 337 N VAL C 317
SHEET 1 AA7 3 MET D 193 LEU D 194 0
SHEET 2 AA7 3 THR D 298 ASN D 309 -1 O TYR D 308 N MET D 193
SHEET 3 AA7 3 GLN D 202 LYS D 204 -1 N LEU D 203 O VAL D 300
SHEET 1 AA8 4 MET D 193 LEU D 194 0
SHEET 2 AA8 4 THR D 298 ASN D 309 -1 O TYR D 308 N MET D 193
SHEET 3 AA8 4 LEU D 314 GLU D 323 -1 O LEU D 318 N PHE D 305
SHEET 4 AA8 4 SER D 333 VAL D 339 -1 O ARG D 337 N VAL D 317
LINK ND2 ASN A 207 C1 NAG A 901 1555 1555 1.44
LINK ND2 ASN A 207 O5 NAG A 901 1555 1555 1.49
LINK ND2 ASN B 207 C1 NAG B 901 1555 1555 1.44
LINK ND2 ASN B 207 O5 NAG B 901 1555 1555 1.49
LINK ND2 ASN C 207 C1 NAG C 901 1555 1555 1.44
LINK ND2 ASN C 207 O5 NAG C 901 1555 1555 1.49
LINK ND2 ASN D 207 C1 NAG D 901 1555 1555 1.44
LINK ND2 ASN D 207 O5 NAG D 901 1555 1555 1.49
CRYST1 1.000 1.000 1.000 90.00 90.00 90.00 P 1 1
ORIGX1 1.000000 0.000000 0.000000 0.00000
ORIGX2 0.000000 1.000000 0.000000 0.00000
ORIGX3 0.000000 0.000000 1.000000 0.00000
SCALE1 1.000000 0.000000 0.000000 0.00000
SCALE2 0.000000 1.000000 0.000000 0.00000
SCALE3 0.000000 0.000000 1.000000 0.00000
(ATOM LINES ARE NOT SHOWN.)
END
