HEADER MOTOR PROTEIN 23-NOV-17 6F1Z
TITLE ROADBLOCK-1 REGION OF THE DYNEIN TAIL/DYNACTIN/BICDR1 COMPLEX
COMPND MOL_ID: 1;
COMPND 2 MOLECULE: CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN 2;
COMPND 3 CHAIN: o, p;
COMPND 4 SYNONYM: CYTOPLASMIC DYNEIN INTERMEDIATE CHAIN 2,DYNEIN INTERMEDIATE
COMPND 5 CHAIN 2,CYTOSOLIC,DH IC-2;
COMPND 6 ENGINEERED: YES;
COMPND 7 MOL_ID: 2;
COMPND 8 MOLECULE: DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 1;
COMPND 9 CHAIN: s, t;
COMPND 10 SYNONYM: BITHORAXOID-LIKE PROTEIN,BLP,DYNEIN LIGHT CHAIN 2A,
COMPND 11 CYTOPLASMIC,DYNEIN-ASSOCIATED PROTEIN KM23,ROADBLOCK DOMAIN-
COMPND 12 CONTAINING PROTEIN 1;
COMPND 13 ENGINEERED: YES
SOURCE MOL_ID: 1;
SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS;
SOURCE 3 ORGANISM_COMMON: HUMAN;
SOURCE 4 ORGANISM_TAXID: 9606;
SOURCE 5 GENE: DYNC1I2, DNCI2, DNCIC2;
SOURCE 6 EXPRESSION_SYSTEM: SPODOPTERA FRUGIPERDA;
SOURCE 7 EXPRESSION_SYSTEM_TAXID: 7108;
SOURCE 8 MOL_ID: 2;
SOURCE 9 ORGANISM_SCIENTIFIC: HOMO SAPIENS;
SOURCE 10 ORGANISM_COMMON: HUMAN;
SOURCE 11 ORGANISM_TAXID: 9606;
SOURCE 12 GENE: DYNLRB1, BITH, DNCL2A, DNLC2A, ROBLD1, HSPC162;
SOURCE 13 EXPRESSION_SYSTEM: SPODOPTERA FRUGIPERDA;
SOURCE 14 EXPRESSION_SYSTEM_TAXID: 7108;
SOURCE 15 EXPRESSION_SYSTEM_CELL_LINE: SF9
KEYWDS CRYO-EM, COMPLEX, MOTOR PROTEIN
EXPDTA ELECTRON MICROSCOPY
AUTHOR L.URNAVICIUS,C.K.LAU,M.M.ELSHENAWY,E.MORALES-RIOS,C.MOTZ,A.YILDIZ,
AUTHOR 2 A.P.CARTER
REVDAT 5 10-FEB-21 6F1Z 1 REMARK
REVDAT 4 11-DEC-19 6F1Z 1 SCALE
REVDAT 3 21-FEB-18 6F1Z 1 JRNL
REVDAT 2 31-JAN-18 6F1Z 1 JRNL REMARK
REVDAT 1 17-JAN-18 6F1Z 0
JRNL AUTH L.URNAVICIUS,C.K.LAU,M.M.ELSHENAWY,E.MORALES-RIOS,C.MOTZ,
JRNL AUTH 2 A.YILDIZ,A.P.CARTER
JRNL TITL CRYO-EM SHOWS HOW DYNACTIN RECRUITS TWO DYNEINS FOR FASTER
JRNL TITL 2 MOVEMENT.
JRNL REF NATURE V. 554 202 2018
JRNL REFN ESSN 1476-4687
JRNL PMID 29420470
JRNL DOI 10.1038/NATURE25462
REMARK 2
REMARK 2 RESOLUTION. 3.40 ANGSTROMS.
REMARK 3
REMARK 3 REFINEMENT.
REMARK 3 SOFTWARE PACKAGES : RELION, CTFFIND, COOT, RELION, RELION,
REMARK 3 RELION, RELION, PHENIX
REMARK 3 RECONSTRUCTION SCHEMA : NULL
REMARK 3
REMARK 3 EM MAP-MODEL FITTING AND REFINEMENT
REMARK 3 PDB ENTRY : NULL
REMARK 3 REFINEMENT SPACE : REAL
REMARK 3 REFINEMENT PROTOCOL : FLEXIBLE FIT
REMARK 3 REFINEMENT TARGET : CROSS-CORRELATION COEFFICIENT
REMARK 3 OVERALL ANISOTROPIC B VALUE : NULL
REMARK 3
REMARK 3 FITTING PROCEDURE : NULL
REMARK 3
REMARK 3 EM IMAGE RECONSTRUCTION STATISTICS
REMARK 3 NOMINAL PIXEL SIZE (ANGSTROMS) : NULL
REMARK 3 ACTUAL PIXEL SIZE (ANGSTROMS) : NULL
REMARK 3 EFFECTIVE RESOLUTION (ANGSTROMS) : 3.400
REMARK 3 NUMBER OF PARTICLES : 77136
REMARK 3 CTF CORRECTION METHOD : PHASE FLIPPING AND AMPLITUDE
REMARK 3 CORRECTION
REMARK 3
REMARK 3 EM RECONSTRUCTION MAGNIFICATION CALIBRATION: NULL
REMARK 3
REMARK 3 OTHER DETAILS: NULL
REMARK 4
REMARK 4 6F1Z COMPLIES WITH FORMAT V. 3.30, 13-JUL-11
REMARK 100
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBE ON 23-NOV-17.
REMARK 100 THE DEPOSITION ID IS D_1200007575.
REMARK 245
REMARK 245 EXPERIMENTAL DETAILS
REMARK 245 RECONSTRUCTION METHOD : SINGLE PARTICLE
REMARK 245 SPECIMEN TYPE : NULL
REMARK 245
REMARK 245 ELECTRON MICROSCOPE SAMPLE
REMARK 245 SAMPLE TYPE : PARTICLE
REMARK 245 PARTICLE TYPE : POINT
REMARK 245 NAME OF SAMPLE : TWO DYNEIN TAIL DOMAINS,
REMARK 245 DYNACTIN AND BICDR1
REMARK 245 SAMPLE CONCENTRATION (MG ML-1) : NULL
REMARK 245 SAMPLE SUPPORT DETAILS : NULL
REMARK 245 SAMPLE VITRIFICATION DETAILS : NULL
REMARK 245 SAMPLE BUFFER : NULL
REMARK 245 PH : 7.40
REMARK 245 SAMPLE DETAILS : NULL
REMARK 245
REMARK 245 DATA ACQUISITION
REMARK 245 DATE OF EXPERIMENT : NULL
REMARK 245 NUMBER OF MICROGRAPHS-IMAGES : NULL
REMARK 245 TEMPERATURE (KELVIN) : NULL
REMARK 245 MICROSCOPE MODEL : FEI TITAN KRIOS
REMARK 245 DETECTOR TYPE : FEI FALCON II (4K X 4K)
REMARK 245 MINIMUM DEFOCUS (NM) : NULL
REMARK 245 MAXIMUM DEFOCUS (NM) : NULL
REMARK 245 MINIMUM TILT ANGLE (DEGREES) : NULL
REMARK 245 MAXIMUM TILT ANGLE (DEGREES) : NULL
REMARK 245 NOMINAL CS : NULL
REMARK 245 IMAGING MODE : BRIGHT FIELD
REMARK 245 ELECTRON DOSE (ELECTRONS NM**-2) : 52.00
REMARK 245 ILLUMINATION MODE : FLOOD BEAM
REMARK 245 NOMINAL MAGNIFICATION : NULL
REMARK 245 CALIBRATED MAGNIFICATION : NULL
REMARK 245 SOURCE : FIELD EMISSION GUN
REMARK 245 ACCELERATION VOLTAGE (KV) : 300
REMARK 245 IMAGING DETAILS : NULL
REMARK 247
REMARK 247 ELECTRON MICROSCOPY
REMARK 247 THE COORDINATES IN THIS ENTRY WERE GENERATED FROM ELECTRON
REMARK 247 MICROSCOPY DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE
REMARK 247 THAT CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES
REMARK 247 ON THESE RECORDS ARE MEANINGLESS EXCEPT FOR THE CALCULATION
REMARK 247 OF THE STRUCTURE FACTORS.
REMARK 300
REMARK 300 BIOMOLECULE: 1
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON
REMARK 300 BURIED SURFACE AREA.
REMARK 350
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS
REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.
REMARK 350
REMARK 350 BIOMOLECULE: 1
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TETRAMERIC
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TETRAMERIC
REMARK 350 SOFTWARE USED: PISA
REMARK 350 TOTAL BURIED SURFACE AREA: 6640 ANGSTROM**2
REMARK 350 SURFACE AREA OF THE COMPLEX: 15790 ANGSTROM**2
REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -39.0 KCAL/MOL
REMARK 350 APPLY THE FOLLOWING TO CHAINS: o, p, s, t
REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000
REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000
REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000
REMARK 465
REMARK 465 MISSING RESIDUES
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)
REMARK 465
REMARK 465 M RES C SSSEQI
REMARK 465 MET o 1
REMARK 465 SER o 2
REMARK 465 ASP o 3
REMARK 465 LYS o 4
REMARK 465 SER o 5
REMARK 465 GLU o 6
REMARK 465 LEU o 7
REMARK 465 LYS o 8
REMARK 465 ALA o 9
REMARK 465 GLU o 10
REMARK 465 LEU o 11
REMARK 465 GLU o 12
REMARK 465 ARG o 13
REMARK 465 LYS o 14
REMARK 465 LYS o 15
REMARK 465 GLN o 16
REMARK 465 ARG o 17
REMARK 465 LEU o 18
REMARK 465 ALA o 19
REMARK 465 GLN o 20
REMARK 465 ILE o 21
REMARK 465 ARG o 22
REMARK 465 GLU o 23
REMARK 465 GLU o 24
REMARK 465 LYS o 25
REMARK 465 LYS o 26
REMARK 465 ARG o 27
REMARK 465 LYS o 28
REMARK 465 GLU o 29
REMARK 465 GLU o 30
REMARK 465 GLU o 31
REMARK 465 ARG o 32
REMARK 465 LYS o 33
REMARK 465 LYS o 34
REMARK 465 LYS o 35
REMARK 465 GLU o 36
REMARK 465 THR o 37
REMARK 465 ASP o 38
REMARK 465 GLN o 39
REMARK 465 LYS o 40
REMARK 465 LYS o 41
REMARK 465 GLU o 42
REMARK 465 ALA o 43
REMARK 465 VAL o 44
REMARK 465 ALA o 45
REMARK 465 PRO o 46
REMARK 465 VAL o 47
REMARK 465 GLN o 48
REMARK 465 GLU o 49
REMARK 465 GLU o 50
REMARK 465 SER o 51
REMARK 465 ASP o 52
REMARK 465 LEU o 53
REMARK 465 GLU o 54
REMARK 465 LYS o 55
REMARK 465 LYS o 56
REMARK 465 ARG o 57
REMARK 465 ARG o 58
REMARK 465 GLU o 59
REMARK 465 ALA o 60
REMARK 465 GLU o 61
REMARK 465 ALA o 62
REMARK 465 LEU o 63
REMARK 465 LEU o 64
REMARK 465 GLN o 65
REMARK 465 SER o 66
REMARK 465 MET o 67
REMARK 465 GLY o 68
REMARK 465 LEU o 69
REMARK 465 THR o 70
REMARK 465 PRO o 71
REMARK 465 GLU o 72
REMARK 465 SER o 73
REMARK 465 PRO o 74
REMARK 465 ILE o 75
REMARK 465 VAL o 76
REMARK 465 PRO o 77
REMARK 465 PRO o 78
REMARK 465 PRO o 79
REMARK 465 MET o 80
REMARK 465 SER o 81
REMARK 465 PRO o 82
REMARK 465 SER o 83
REMARK 465 SER o 84
REMARK 465 LYS o 85
REMARK 465 SER o 86
REMARK 465 VAL o 87
REMARK 465 SER o 88
REMARK 465 THR o 89
REMARK 465 PRO o 90
REMARK 465 SER o 91
REMARK 465 GLU o 92
REMARK 465 ALA o 93
REMARK 465 GLY o 94
REMARK 465 SER o 95
REMARK 465 GLN o 96
REMARK 465 ASP o 97
REMARK 465 SER o 98
REMARK 465 GLY o 99
REMARK 465 ASP o 100
REMARK 465 GLY o 101
REMARK 465 ALA o 102
REMARK 465 VAL o 103
REMARK 465 GLY o 104
REMARK 465 SER o 105
REMARK 465 ARG o 106
REMARK 465 ARG o 107
REMARK 465 GLY o 108
REMARK 465 PRO o 109
REMARK 465 ILE o 110
REMARK 465 LYS o 111
REMARK 465 LEU o 112
REMARK 465 GLY o 113
REMARK 465 MET o 114
REMARK 465 ALA o 115
REMARK 465 LYS o 116
REMARK 465 ILE o 117
REMARK 465 THR o 118
REMARK 465 GLN o 119
REMARK 465 VAL o 120
REMARK 465 ASP o 121
REMARK 465 PHE o 122
REMARK 465 PRO o 123
REMARK 465 PRO o 124
REMARK 465 ARG o 125
REMARK 465 GLU o 126
REMARK 465 ILE o 127
REMARK 465 VAL o 128
REMARK 465 THR o 129
REMARK 465 TYR o 130
REMARK 465 THR o 131
REMARK 465 LYS o 132
REMARK 465 GLU o 133
REMARK 465 THR o 134
REMARK 465 GLN o 135
REMARK 465 THR o 136
REMARK 465 PRO o 137
REMARK 465 VAL o 138
REMARK 465 MET o 139
REMARK 465 ALA o 140
REMARK 465 GLN o 141
REMARK 465 PRO o 142
REMARK 465 LYS o 143
REMARK 465 GLU o 144
REMARK 465 ASP o 145
REMARK 465 GLU o 146
REMARK 465 GLU o 147
REMARK 465 GLU o 148
REMARK 465 ASP o 149
REMARK 465 ASP o 150
REMARK 465 ASP o 151
REMARK 465 VAL o 152
REMARK 465 VAL o 153
REMARK 465 ALA o 154
REMARK 465 PRO o 155
REMARK 465 LYS o 156
REMARK 465 PRO o 157
REMARK 465 PRO o 158
REMARK 465 ILE o 159
REMARK 465 GLU o 160
REMARK 465 PRO o 161
REMARK 465 GLU o 162
REMARK 465 GLU o 163
REMARK 465 GLU o 164
REMARK 465 LYS o 165
REMARK 465 THR o 166
REMARK 465 LEU o 167
REMARK 465 LYS o 168
REMARK 465 LYS o 169
REMARK 465 ASP o 170
REMARK 465 GLU o 171
REMARK 465 GLU o 172
REMARK 465 ASN o 173
REMARK 465 ASP o 174
REMARK 465 SER o 175
REMARK 465 LYS o 176
REMARK 465 ALA o 177
REMARK 465 PRO o 178
REMARK 465 PRO o 179
REMARK 465 HIS o 180
REMARK 465 GLU o 181
REMARK 465 PHE o 218
REMARK 465 PHE o 219
REMARK 465 ASP o 220
REMARK 465 TYR o 221
REMARK 465 SER o 222
REMARK 465 GLY o 223
REMARK 465 ARG o 224
REMARK 465 ASP o 225
REMARK 465 LEU o 226
REMARK 465 GLU o 227
REMARK 465 ASP o 228
REMARK 465 LYS o 229
REMARK 465 GLU o 230
REMARK 465 GLY o 231
REMARK 465 GLU o 232
REMARK 465 ILE o 233
REMARK 465 GLN o 234
REMARK 465 ALA o 235
REMARK 465 GLY o 236
REMARK 465 ALA o 237
REMARK 465 LYS o 238
REMARK 465 LEU o 239
REMARK 465 SER o 240
REMARK 465 LEU o 241
REMARK 465 ASN o 242
REMARK 465 ARG o 243
REMARK 465 GLN o 244
REMARK 465 PHE o 245
REMARK 465 PHE o 246
REMARK 465 ASP o 247
REMARK 465 GLU o 248
REMARK 465 ARG o 249
REMARK 465 TRP o 250
REMARK 465 SER o 251
REMARK 465 LYS o 252
REMARK 465 HIS o 253
REMARK 465 ARG o 254
REMARK 465 VAL o 255
REMARK 465 VAL o 256
REMARK 465 SER o 257
REMARK 465 CYS o 258
REMARK 465 LEU o 259
REMARK 465 ASP o 260
REMARK 465 TRP o 261
REMARK 465 SER o 262
REMARK 465 SER o 263
REMARK 465 GLN o 264
REMARK 465 TYR o 265
REMARK 465 PRO o 266
REMARK 465 GLU o 267
REMARK 465 LEU o 268
REMARK 465 LEU o 269
REMARK 465 VAL o 270
REMARK 465 ALA o 271
REMARK 465 SER o 272
REMARK 465 TYR o 273
REMARK 465 ASN o 274
REMARK 465 ASN o 275
REMARK 465 ASN o 276
REMARK 465 GLU o 277
REMARK 465 ASP o 278
REMARK 465 ALA o 279
REMARK 465 PRO o 280
REMARK 465 HIS o 281
REMARK 465 GLU o 282
REMARK 465 PRO o 283
REMARK 465 ASP o 284
REMARK 465 GLY o 285
REMARK 465 VAL o 286
REMARK 465 ALA o 287
REMARK 465 LEU o 288
REMARK 465 VAL o 289
REMARK 465 TRP o 290
REMARK 465 ASN o 291
REMARK 465 MET o 292
REMARK 465 LYS o 293
REMARK 465 TYR o 294
REMARK 465 LYS o 295
REMARK 465 LYS o 296
REMARK 465 THR o 297
REMARK 465 THR o 298
REMARK 465 PRO o 299
REMARK 465 GLU o 300
REMARK 465 TYR o 301
REMARK 465 VAL o 302
REMARK 465 PHE o 303
REMARK 465 HIS o 304
REMARK 465 CYS o 305
REMARK 465 GLN o 306
REMARK 465 SER o 307
REMARK 465 ALA o 308
REMARK 465 VAL o 309
REMARK 465 MET o 310
REMARK 465 SER o 311
REMARK 465 ALA o 312
REMARK 465 THR o 313
REMARK 465 PHE o 314
REMARK 465 ALA o 315
REMARK 465 LYS o 316
REMARK 465 PHE o 317
REMARK 465 HIS o 318
REMARK 465 PRO o 319
REMARK 465 ASN o 320
REMARK 465 LEU o 321
REMARK 465 VAL o 322
REMARK 465 VAL o 323
REMARK 465 GLY o 324
REMARK 465 GLY o 325
REMARK 465 THR o 326
REMARK 465 TYR o 327
REMARK 465 SER o 328
REMARK 465 GLY o 329
REMARK 465 GLN o 330
REMARK 465 ILE o 331
REMARK 465 VAL o 332
REMARK 465 LEU o 333
REMARK 465 TRP o 334
REMARK 465 ASP o 335
REMARK 465 ASN o 336
REMARK 465 ARG o 337
REMARK 465 SER o 338
REMARK 465 ASN o 339
REMARK 465 LYS o 340
REMARK 465 ARG o 341
REMARK 465 THR o 342
REMARK 465 PRO o 343
REMARK 465 VAL o 344
REMARK 465 GLN o 345
REMARK 465 ARG o 346
REMARK 465 THR o 347
REMARK 465 PRO o 348
REMARK 465 LEU o 349
REMARK 465 SER o 350
REMARK 465 ALA o 351
REMARK 465 ALA o 352
REMARK 465 ALA o 353
REMARK 465 HIS o 354
REMARK 465 THR o 355
REMARK 465 HIS o 356
REMARK 465 PRO o 357
REMARK 465 VAL o 358
REMARK 465 TYR o 359
REMARK 465 CYS o 360
REMARK 465 VAL o 361
REMARK 465 ASN o 362
REMARK 465 VAL o 363
REMARK 465 VAL o 364
REMARK 465 GLY o 365
REMARK 465 THR o 366
REMARK 465 GLN o 367
REMARK 465 ASN o 368
REMARK 465 ALA o 369
REMARK 465 HIS o 370
REMARK 465 ASN o 371
REMARK 465 LEU o 372
REMARK 465 ILE o 373
REMARK 465 SER o 374
REMARK 465 ILE o 375
REMARK 465 SER o 376
REMARK 465 THR o 377
REMARK 465 ASP o 378
REMARK 465 GLY o 379
REMARK 465 LYS o 380
REMARK 465 ILE o 381
REMARK 465 CYS o 382
REMARK 465 SER o 383
REMARK 465 TRP o 384
REMARK 465 SER o 385
REMARK 465 LEU o 386
REMARK 465 ASP o 387
REMARK 465 MET o 388
REMARK 465 LEU o 389
REMARK 465 SER o 390
REMARK 465 HIS o 391
REMARK 465 PRO o 392
REMARK 465 GLN o 393
REMARK 465 ASP o 394
REMARK 465 SER o 395
REMARK 465 MET o 396
REMARK 465 GLU o 397
REMARK 465 LEU o 398
REMARK 465 VAL o 399
REMARK 465 HIS o 400
REMARK 465 LYS o 401
REMARK 465 GLN o 402
REMARK 465 SER o 403
REMARK 465 LYS o 404
REMARK 465 ALA o 405
REMARK 465 VAL o 406
REMARK 465 ALA o 407
REMARK 465 VAL o 408
REMARK 465 THR o 409
REMARK 465 SER o 410
REMARK 465 MET o 411
REMARK 465 SER o 412
REMARK 465 PHE o 413
REMARK 465 PRO o 414
REMARK 465 VAL o 415
REMARK 465 GLY o 416
REMARK 465 ASP o 417
REMARK 465 VAL o 418
REMARK 465 ASN o 419
REMARK 465 ASN o 420
REMARK 465 PHE o 421
REMARK 465 VAL o 422
REMARK 465 VAL o 423
REMARK 465 GLY o 424
REMARK 465 SER o 425
REMARK 465 GLU o 426
REMARK 465 GLU o 427
REMARK 465 GLY o 428
REMARK 465 SER o 429
REMARK 465 VAL o 430
REMARK 465 TYR o 431
REMARK 465 THR o 432
REMARK 465 ALA o 433
REMARK 465 CYS o 434
REMARK 465 ARG o 435
REMARK 465 HIS o 436
REMARK 465 GLY o 437
REMARK 465 SER o 438
REMARK 465 LYS o 439
REMARK 465 ALA o 440
REMARK 465 GLY o 441
REMARK 465 ILE o 442
REMARK 465 SER o 443
REMARK 465 GLU o 444
REMARK 465 MET o 445
REMARK 465 PHE o 446
REMARK 465 GLU o 447
REMARK 465 GLY o 448
REMARK 465 HIS o 449
REMARK 465 GLN o 450
REMARK 465 GLY o 451
REMARK 465 PRO o 452
REMARK 465 ILE o 453
REMARK 465 THR o 454
REMARK 465 GLY o 455
REMARK 465 ILE o 456
REMARK 465 HIS o 457
REMARK 465 CYS o 458
REMARK 465 HIS o 459
REMARK 465 ALA o 460
REMARK 465 ALA o 461
REMARK 465 VAL o 462
REMARK 465 GLY o 463
REMARK 465 ALA o 464
REMARK 465 VAL o 465
REMARK 465 ASP o 466
REMARK 465 PHE o 467
REMARK 465 SER o 468
REMARK 465 HIS o 469
REMARK 465 LEU o 470
REMARK 465 PHE o 471
REMARK 465 VAL o 472
REMARK 465 THR o 473
REMARK 465 SER o 474
REMARK 465 SER o 475
REMARK 465 PHE o 476
REMARK 465 ASP o 477
REMARK 465 TRP o 478
REMARK 465 THR o 479
REMARK 465 VAL o 480
REMARK 465 LYS o 481
REMARK 465 LEU o 482
REMARK 465 TRP o 483
REMARK 465 SER o 484
REMARK 465 THR o 485
REMARK 465 LYS o 486
REMARK 465 ASN o 487
REMARK 465 ASN o 488
REMARK 465 LYS o 489
REMARK 465 PRO o 490
REMARK 465 LEU o 491
REMARK 465 TYR o 492
REMARK 465 SER o 493
REMARK 465 PHE o 494
REMARK 465 GLU o 495
REMARK 465 ASP o 496
REMARK 465 ASN o 497
REMARK 465 ALA o 498
REMARK 465 GLY o 499
REMARK 465 TYR o 500
REMARK 465 VAL o 501
REMARK 465 TYR o 502
REMARK 465 ASP o 503
REMARK 465 VAL o 504
REMARK 465 MET o 505
REMARK 465 TRP o 506
REMARK 465 SER o 507
REMARK 465 PRO o 508
REMARK 465 THR o 509
REMARK 465 HIS o 510
REMARK 465 PRO o 511
REMARK 465 ALA o 512
REMARK 465 LEU o 513
REMARK 465 PHE o 514
REMARK 465 ALA o 515
REMARK 465 CYS o 516
REMARK 465 VAL o 517
REMARK 465 ASP o 518
REMARK 465 GLY o 519
REMARK 465 MET o 520
REMARK 465 GLY o 521
REMARK 465 ARG o 522
REMARK 465 LEU o 523
REMARK 465 ASP o 524
REMARK 465 LEU o 525
REMARK 465 TRP o 526
REMARK 465 ASN o 527
REMARK 465 LEU o 528
REMARK 465 ASN o 529
REMARK 465 ASN o 530
REMARK 465 ASP o 531
REMARK 465 THR o 532
REMARK 465 GLU o 533
REMARK 465 VAL o 534
REMARK 465 PRO o 535
REMARK 465 THR o 536
REMARK 465 ALA o 537
REMARK 465 SER o 538
REMARK 465 ILE o 539
REMARK 465 SER o 540
REMARK 465 VAL o 541
REMARK 465 GLU o 542
REMARK 465 GLY o 543
REMARK 465 ASN o 544
REMARK 465 PRO o 545
REMARK 465 ALA o 546
REMARK 465 LEU o 547
REMARK 465 ASN o 548
REMARK 465 ARG o 549
REMARK 465 VAL o 550
REMARK 465 ARG o 551
REMARK 465 TRP o 552
REMARK 465 THR o 553
REMARK 465 HIS o 554
REMARK 465 SER o 555
REMARK 465 GLY o 556
REMARK 465 ARG o 557
REMARK 465 GLU o 558
REMARK 465 ILE o 559
REMARK 465 ALA o 560
REMARK 465 VAL o 561
REMARK 465 GLY o 562
REMARK 465 ASP o 563
REMARK 465 SER o 564
REMARK 465 GLU o 565
REMARK 465 GLY o 566
REMARK 465 GLN o 567
REMARK 465 ILE o 568
REMARK 465 VAL o 569
REMARK 465 ILE o 570
REMARK 465 TYR o 571
REMARK 465 ASP o 572
REMARK 465 VAL o 573
REMARK 465 GLY o 574
REMARK 465 GLU o 575
REMARK 465 GLN o 576
REMARK 465 ILE o 577
REMARK 465 ALA o 578
REMARK 465 VAL o 579
REMARK 465 PRO o 580
REMARK 465 ARG o 581
REMARK 465 ASN o 582
REMARK 465 ASP o 583
REMARK 465 GLU o 584
REMARK 465 TRP o 585
REMARK 465 ALA o 586
REMARK 465 ARG o 587
REMARK 465 PHE o 588
REMARK 465 GLY o 589
REMARK 465 ARG o 590
REMARK 465 THR o 591
REMARK 465 LEU o 592
REMARK 465 ALA o 593
REMARK 465 GLU o 594
REMARK 465 ILE o 595
REMARK 465 ASN o 596
REMARK 465 ALA o 597
REMARK 465 ASN o 598
REMARK 465 ARG o 599
REMARK 465 ALA o 600
REMARK 465 ASP o 601
REMARK 465 ALA o 602
REMARK 465 GLU o 603
REMARK 465 GLU o 604
REMARK 465 GLU o 605
REMARK 465 ALA o 606
REMARK 465 ALA o 607
REMARK 465 THR o 608
REMARK 465 ARG o 609
REMARK 465 ILE o 610
REMARK 465 PRO o 611
REMARK 465 ALA o 612
REMARK 465 MET p 1
REMARK 465 SER p 2
REMARK 465 ASP p 3
REMARK 465 LYS p 4
REMARK 465 SER p 5
REMARK 465 GLU p 6
REMARK 465 LEU p 7
REMARK 465 LYS p 8
REMARK 465 ALA p 9
REMARK 465 GLU p 10
REMARK 465 LEU p 11
REMARK 465 GLU p 12
REMARK 465 ARG p 13
REMARK 465 LYS p 14
REMARK 465 LYS p 15
REMARK 465 GLN p 16
REMARK 465 ARG p 17
REMARK 465 LEU p 18
REMARK 465 ALA p 19
REMARK 465 GLN p 20
REMARK 465 ILE p 21
REMARK 465 ARG p 22
REMARK 465 GLU p 23
REMARK 465 GLU p 24
REMARK 465 LYS p 25
REMARK 465 LYS p 26
REMARK 465 ARG p 27
REMARK 465 LYS p 28
REMARK 465 GLU p 29
REMARK 465 GLU p 30
REMARK 465 GLU p 31
REMARK 465 ARG p 32
REMARK 465 LYS p 33
REMARK 465 LYS p 34
REMARK 465 LYS p 35
REMARK 465 GLU p 36
REMARK 465 THR p 37
REMARK 465 ASP p 38
REMARK 465 GLN p 39
REMARK 465 LYS p 40
REMARK 465 LYS p 41
REMARK 465 GLU p 42
REMARK 465 ALA p 43
REMARK 465 VAL p 44
REMARK 465 ALA p 45
REMARK 465 PRO p 46
REMARK 465 VAL p 47
REMARK 465 GLN p 48
REMARK 465 GLU p 49
REMARK 465 GLU p 50
REMARK 465 SER p 51
REMARK 465 ASP p 52
REMARK 465 LEU p 53
REMARK 465 GLU p 54
REMARK 465 LYS p 55
REMARK 465 LYS p 56
REMARK 465 ARG p 57
REMARK 465 ARG p 58
REMARK 465 GLU p 59
REMARK 465 ALA p 60
REMARK 465 GLU p 61
REMARK 465 ALA p 62
REMARK 465 LEU p 63
REMARK 465 LEU p 64
REMARK 465 GLN p 65
REMARK 465 SER p 66
REMARK 465 MET p 67
REMARK 465 GLY p 68
REMARK 465 LEU p 69
REMARK 465 THR p 70
REMARK 465 PRO p 71
REMARK 465 GLU p 72
REMARK 465 SER p 73
REMARK 465 PRO p 74
REMARK 465 ILE p 75
REMARK 465 VAL p 76
REMARK 465 PRO p 77
REMARK 465 PRO p 78
REMARK 465 PRO p 79
REMARK 465 MET p 80
REMARK 465 SER p 81
REMARK 465 PRO p 82
REMARK 465 SER p 83
REMARK 465 SER p 84
REMARK 465 LYS p 85
REMARK 465 SER p 86
REMARK 465 VAL p 87
REMARK 465 SER p 88
REMARK 465 THR p 89
REMARK 465 PRO p 90
REMARK 465 SER p 91
REMARK 465 GLU p 92
REMARK 465 ALA p 93
REMARK 465 GLY p 94
REMARK 465 SER p 95
REMARK 465 GLN p 96
REMARK 465 ASP p 97
REMARK 465 SER p 98
REMARK 465 GLY p 99
REMARK 465 ASP p 100
REMARK 465 GLY p 101
REMARK 465 ALA p 102
REMARK 465 VAL p 103
REMARK 465 GLY p 104
REMARK 465 SER p 105
REMARK 465 ARG p 106
REMARK 465 ARG p 107
REMARK 465 GLY p 108
REMARK 465 PRO p 109
REMARK 465 ILE p 110
REMARK 465 LYS p 111
REMARK 465 LEU p 112
REMARK 465 GLY p 113
REMARK 465 MET p 114
REMARK 465 ALA p 115
REMARK 465 LYS p 116
REMARK 465 ILE p 117
REMARK 465 THR p 118
REMARK 465 GLN p 119
REMARK 465 VAL p 120
REMARK 465 ASP p 121
REMARK 465 PHE p 122
REMARK 465 PRO p 123
REMARK 465 PRO p 124
REMARK 465 ARG p 125
REMARK 465 GLU p 126
REMARK 465 ILE p 127
REMARK 465 VAL p 128
REMARK 465 THR p 129
REMARK 465 TYR p 130
REMARK 465 THR p 131
REMARK 465 LYS p 132
REMARK 465 GLU p 133
REMARK 465 THR p 134
REMARK 465 GLN p 135
REMARK 465 THR p 136
REMARK 465 PRO p 137
REMARK 465 VAL p 138
REMARK 465 MET p 139
REMARK 465 ALA p 140
REMARK 465 GLN p 141
REMARK 465 PRO p 142
REMARK 465 LYS p 143
REMARK 465 GLU p 144
REMARK 465 ASP p 145
REMARK 465 GLU p 146
REMARK 465 GLU p 147
REMARK 465 GLU p 148
REMARK 465 ASP p 149
REMARK 465 ASP p 150
REMARK 465 ASP p 151
REMARK 465 VAL p 152
REMARK 465 VAL p 153
REMARK 465 ALA p 154
REMARK 465 PRO p 155
REMARK 465 LYS p 156
REMARK 465 PRO p 157
REMARK 465 PRO p 158
REMARK 465 ILE p 159
REMARK 465 GLU p 160
REMARK 465 PRO p 161
REMARK 465 GLU p 162
REMARK 465 GLU p 163
REMARK 465 GLU p 164
REMARK 465 LYS p 165
REMARK 465 THR p 166
REMARK 465 LEU p 167
REMARK 465 LYS p 168
REMARK 465 LYS p 169
REMARK 465 ASP p 170
REMARK 465 GLU p 171
REMARK 465 GLU p 172
REMARK 465 ASN p 173
REMARK 465 ASP p 174
REMARK 465 SER p 175
REMARK 465 LYS p 176
REMARK 465 ALA p 177
REMARK 465 PRO p 178
REMARK 465 PRO p 179
REMARK 465 HIS p 180
REMARK 465 GLU p 181
REMARK 465 ASP p 225
REMARK 465 LEU p 226
REMARK 465 GLU p 227
REMARK 465 ASP p 228
REMARK 465 LYS p 229
REMARK 465 GLU p 230
REMARK 465 GLY p 231
REMARK 465 GLU p 232
REMARK 465 ILE p 233
REMARK 465 GLN p 234
REMARK 465 ALA p 235
REMARK 465 GLY p 236
REMARK 465 ALA p 237
REMARK 465 LYS p 238
REMARK 465 LEU p 239
REMARK 465 SER p 240
REMARK 465 LEU p 241
REMARK 465 ASN p 242
REMARK 465 ARG p 243
REMARK 465 GLN p 244
REMARK 465 PHE p 245
REMARK 465 PHE p 246
REMARK 465 ASP p 247
REMARK 465 GLU p 248
REMARK 465 ARG p 249
REMARK 465 TRP p 250
REMARK 465 SER p 251
REMARK 465 LYS p 252
REMARK 465 HIS p 253
REMARK 465 ARG p 254
REMARK 465 VAL p 255
REMARK 465 VAL p 256
REMARK 465 SER p 257
REMARK 465 CYS p 258
REMARK 465 LEU p 259
REMARK 465 ASP p 260
REMARK 465 TRP p 261
REMARK 465 SER p 262
REMARK 465 SER p 263
REMARK 465 GLN p 264
REMARK 465 TYR p 265
REMARK 465 PRO p 266
REMARK 465 GLU p 267
REMARK 465 LEU p 268
REMARK 465 LEU p 269
REMARK 465 VAL p 270
REMARK 465 ALA p 271
REMARK 465 SER p 272
REMARK 465 TYR p 273
REMARK 465 ASN p 274
REMARK 465 ASN p 275
REMARK 465 ASN p 276
REMARK 465 GLU p 277
REMARK 465 ASP p 278
REMARK 465 ALA p 279
REMARK 465 PRO p 280
REMARK 465 HIS p 281
REMARK 465 GLU p 282
REMARK 465 PRO p 283
REMARK 465 ASP p 284
REMARK 465 GLY p 285
REMARK 465 VAL p 286
REMARK 465 ALA p 287
REMARK 465 LEU p 288
REMARK 465 VAL p 289
REMARK 465 TRP p 290
REMARK 465 ASN p 291
REMARK 465 MET p 292
REMARK 465 LYS p 293
REMARK 465 TYR p 294
REMARK 465 LYS p 295
REMARK 465 LYS p 296
REMARK 465 THR p 297
REMARK 465 THR p 298
REMARK 465 PRO p 299
REMARK 465 GLU p 300
REMARK 465 TYR p 301
REMARK 465 VAL p 302
REMARK 465 PHE p 303
REMARK 465 HIS p 304
REMARK 465 CYS p 305
REMARK 465 GLN p 306
REMARK 465 SER p 307
REMARK 465 ALA p 308
REMARK 465 VAL p 309
REMARK 465 MET p 310
REMARK 465 SER p 311
REMARK 465 ALA p 312
REMARK 465 THR p 313
REMARK 465 PHE p 314
REMARK 465 ALA p 315
REMARK 465 LYS p 316
REMARK 465 PHE p 317
REMARK 465 HIS p 318
REMARK 465 PRO p 319
REMARK 465 ASN p 320
REMARK 465 LEU p 321
REMARK 465 VAL p 322
REMARK 465 VAL p 323
REMARK 465 GLY p 324
REMARK 465 GLY p 325
REMARK 465 THR p 326
REMARK 465 TYR p 327
REMARK 465 SER p 328
REMARK 465 GLY p 329
REMARK 465 GLN p 330
REMARK 465 ILE p 331
REMARK 465 VAL p 332
REMARK 465 LEU p 333
REMARK 465 TRP p 334
REMARK 465 ASP p 335
REMARK 465 ASN p 336
REMARK 465 ARG p 337
REMARK 465 SER p 338
REMARK 465 ASN p 339
REMARK 465 LYS p 340
REMARK 465 ARG p 341
REMARK 465 THR p 342
REMARK 465 PRO p 343
REMARK 465 VAL p 344
REMARK 465 GLN p 345
REMARK 465 ARG p 346
REMARK 465 THR p 347
REMARK 465 PRO p 348
REMARK 465 LEU p 349
REMARK 465 SER p 350
REMARK 465 ALA p 351
REMARK 465 ALA p 352
REMARK 465 ALA p 353
REMARK 465 HIS p 354
REMARK 465 THR p 355
REMARK 465 HIS p 356
REMARK 465 PRO p 357
REMARK 465 VAL p 358
REMARK 465 TYR p 359
REMARK 465 CYS p 360
REMARK 465 VAL p 361
REMARK 465 ASN p 362
REMARK 465 VAL p 363
REMARK 465 VAL p 364
REMARK 465 GLY p 365
REMARK 465 THR p 366
REMARK 465 GLN p 367
REMARK 465 ASN p 368
REMARK 465 ALA p 369
REMARK 465 HIS p 370
REMARK 465 ASN p 371
REMARK 465 LEU p 372
REMARK 465 ILE p 373
REMARK 465 SER p 374
REMARK 465 ILE p 375
REMARK 465 SER p 376
REMARK 465 THR p 377
REMARK 465 ASP p 378
REMARK 465 GLY p 379
REMARK 465 LYS p 380
REMARK 465 ILE p 381
REMARK 465 CYS p 382
REMARK 465 SER p 383
REMARK 465 TRP p 384
REMARK 465 SER p 385
REMARK 465 LEU p 386
REMARK 465 ASP p 387
REMARK 465 MET p 388
REMARK 465 LEU p 389
REMARK 465 SER p 390
REMARK 465 HIS p 391
REMARK 465 PRO p 392
REMARK 465 GLN p 393
REMARK 465 ASP p 394
REMARK 465 SER p 395
REMARK 465 MET p 396
REMARK 465 GLU p 397
REMARK 465 LEU p 398
REMARK 465 VAL p 399
REMARK 465 HIS p 400
REMARK 465 LYS p 401
REMARK 465 GLN p 402
REMARK 465 SER p 403
REMARK 465 LYS p 404
REMARK 465 ALA p 405
REMARK 465 VAL p 406
REMARK 465 ALA p 407
REMARK 465 VAL p 408
REMARK 465 THR p 409
REMARK 465 SER p 410
REMARK 465 MET p 411
REMARK 465 SER p 412
REMARK 465 PHE p 413
REMARK 465 PRO p 414
REMARK 465 VAL p 415
REMARK 465 GLY p 416
REMARK 465 ASP p 417
REMARK 465 VAL p 418
REMARK 465 ASN p 419
REMARK 465 ASN p 420
REMARK 465 PHE p 421
REMARK 465 VAL p 422
REMARK 465 VAL p 423
REMARK 465 GLY p 424
REMARK 465 SER p 425
REMARK 465 GLU p 426
REMARK 465 GLU p 427
REMARK 465 GLY p 428
REMARK 465 SER p 429
REMARK 465 VAL p 430
REMARK 465 TYR p 431
REMARK 465 THR p 432
REMARK 465 ALA p 433
REMARK 465 CYS p 434
REMARK 465 ARG p 435
REMARK 465 HIS p 436
REMARK 465 GLY p 437
REMARK 465 SER p 438
REMARK 465 LYS p 439
REMARK 465 ALA p 440
REMARK 465 GLY p 441
REMARK 465 ILE p 442
REMARK 465 SER p 443
REMARK 465 GLU p 444
REMARK 465 MET p 445
REMARK 465 PHE p 446
REMARK 465 GLU p 447
REMARK 465 GLY p 448
REMARK 465 HIS p 449
REMARK 465 GLN p 450
REMARK 465 GLY p 451
REMARK 465 PRO p 452
REMARK 465 ILE p 453
REMARK 465 THR p 454
REMARK 465 GLY p 455
REMARK 465 ILE p 456
REMARK 465 HIS p 457
REMARK 465 CYS p 458
REMARK 465 HIS p 459
REMARK 465 ALA p 460
REMARK 465 ALA p 461
REMARK 465 VAL p 462
REMARK 465 GLY p 463
REMARK 465 ALA p 464
REMARK 465 VAL p 465
REMARK 465 ASP p 466
REMARK 465 PHE p 467
REMARK 465 SER p 468
REMARK 465 HIS p 469
REMARK 465 LEU p 470
REMARK 465 PHE p 471
REMARK 465 VAL p 472
REMARK 465 THR p 473
REMARK 465 SER p 474
REMARK 465 SER p 475
REMARK 465 PHE p 476
REMARK 465 ASP p 477
REMARK 465 TRP p 478
REMARK 465 THR p 479
REMARK 465 VAL p 480
REMARK 465 LYS p 481
REMARK 465 LEU p 482
REMARK 465 TRP p 483
REMARK 465 SER p 484
REMARK 465 THR p 485
REMARK 465 LYS p 486
REMARK 465 ASN p 487
REMARK 465 ASN p 488
REMARK 465 LYS p 489
REMARK 465 PRO p 490
REMARK 465 LEU p 491
REMARK 465 TYR p 492
REMARK 465 SER p 493
REMARK 465 PHE p 494
REMARK 465 GLU p 495
REMARK 465 ASP p 496
REMARK 465 ASN p 497
REMARK 465 ALA p 498
REMARK 465 GLY p 499
REMARK 465 TYR p 500
REMARK 465 VAL p 501
REMARK 465 TYR p 502
REMARK 465 ASP p 503
REMARK 465 VAL p 504
REMARK 465 MET p 505
REMARK 465 TRP p 506
REMARK 465 SER p 507
REMARK 465 PRO p 508
REMARK 465 THR p 509
REMARK 465 HIS p 510
REMARK 465 PRO p 511
REMARK 465 ALA p 512
REMARK 465 LEU p 513
REMARK 465 PHE p 514
REMARK 465 ALA p 515
REMARK 465 CYS p 516
REMARK 465 VAL p 517
REMARK 465 ASP p 518
REMARK 465 GLY p 519
REMARK 465 MET p 520
REMARK 465 GLY p 521
REMARK 465 ARG p 522
REMARK 465 LEU p 523
REMARK 465 ASP p 524
REMARK 465 LEU p 525
REMARK 465 TRP p 526
REMARK 465 ASN p 527
REMARK 465 LEU p 528
REMARK 465 ASN p 529
REMARK 465 ASN p 530
REMARK 465 ASP p 531
REMARK 465 THR p 532
REMARK 465 GLU p 533
REMARK 465 VAL p 534
REMARK 465 PRO p 535
REMARK 465 THR p 536
REMARK 465 ALA p 537
REMARK 465 SER p 538
REMARK 465 ILE p 539
REMARK 465 SER p 540
REMARK 465 VAL p 541
REMARK 465 GLU p 542
REMARK 465 GLY p 543
REMARK 465 ASN p 544
REMARK 465 PRO p 545
REMARK 465 ALA p 546
REMARK 465 LEU p 547
REMARK 465 ASN p 548
REMARK 465 ARG p 549
REMARK 465 VAL p 550
REMARK 465 ARG p 551
REMARK 465 TRP p 552
REMARK 465 THR p 553
REMARK 465 HIS p 554
REMARK 465 SER p 555
REMARK 465 GLY p 556
REMARK 465 ARG p 557
REMARK 465 GLU p 558
REMARK 465 ILE p 559
REMARK 465 ALA p 560
REMARK 465 VAL p 561
REMARK 465 GLY p 562
REMARK 465 ASP p 563
REMARK 465 SER p 564
REMARK 465 GLU p 565
REMARK 465 GLY p 566
REMARK 465 GLN p 567
REMARK 465 ILE p 568
REMARK 465 VAL p 569
REMARK 465 ILE p 570
REMARK 465 TYR p 571
REMARK 465 ASP p 572
REMARK 465 VAL p 573
REMARK 465 GLY p 574
REMARK 465 GLU p 575
REMARK 465 GLN p 576
REMARK 465 ILE p 577
REMARK 465 ALA p 578
REMARK 465 VAL p 579
REMARK 465 PRO p 580
REMARK 465 ARG p 581
REMARK 465 ASN p 582
REMARK 465 ASP p 583
REMARK 465 GLU p 584
REMARK 465 TRP p 585
REMARK 465 ALA p 586
REMARK 465 ARG p 587
REMARK 465 PHE p 588
REMARK 465 GLY p 589
REMARK 465 ARG p 590
REMARK 465 THR p 591
REMARK 465 LEU p 592
REMARK 465 ALA p 593
REMARK 465 GLU p 594
REMARK 465 ILE p 595
REMARK 465 ASN p 596
REMARK 465 ALA p 597
REMARK 465 ASN p 598
REMARK 465 ARG p 599
REMARK 465 ALA p 600
REMARK 465 ASP p 601
REMARK 465 ALA p 602
REMARK 465 GLU p 603
REMARK 465 GLU p 604
REMARK 465 GLU p 605
REMARK 465 ALA p 606
REMARK 465 ALA p 607
REMARK 465 THR p 608
REMARK 465 ARG p 609
REMARK 465 ILE p 610
REMARK 465 PRO p 611
REMARK 465 ALA p 612
REMARK 465 MET s 1
REMARK 465 ALA s 2
REMARK 465 GLU s 96
REMARK 465 MET t 1
REMARK 465 ALA t 2
REMARK 465 GLU t 96
REMARK 470
REMARK 470 MISSING ATOM
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;
REMARK 470 I=INSERTION CODE):
REMARK 470 M RES CSSEQI ATOMS
REMARK 470 ASP p 220 CG OD1 OD2
REMARK 470 TYR p 221 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 SER p 222 OG
REMARK 470 ARG p 224 CG CD NE CZ NH1 NH2
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: TORSION ANGLES
REMARK 500
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)
REMARK 500
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400
REMARK 500
REMARK 500 M RES CSSEQI PSI PHI
REMARK 500 GLU o 194 48.75 -92.78
REMARK 500 GLU o 195 -37.33 -130.05
REMARK 500 SER p 193 -169.00 -77.71
REMARK 500 PRO t 29 77.92 -68.74
REMARK 500 MET t 34 -167.16 -119.17
REMARK 500
REMARK 500 REMARK: NULL
REMARK 900
REMARK 900 RELATED ENTRIES
REMARK 900 RELATED ID: EMD-4168 RELATED DB: EMDB
REMARK 900 OVERALL COMPLEX MAP
REMARK 900 RELATED ID: 6F1T RELATED DB: PDB
REMARK 900 OVERALL COMPLEX COORDINATES
REMARK 900 RELATED ID: EMD-4169 RELATED DB: EMDB
REMARK 900 MAP SHOWING DIFFERENT REGION OF SAME COMPLEX.
REMARK 900 RELATED ID: 6F1U RELATED DB: PDB
REMARK 900 COORDINATES OF DIFFERENT REGION OF SAME COMPLEX
REMARK 900 RELATED ID: EMD-4170 RELATED DB: EMDB
REMARK 900 MAP SHOWING SAME REGION, BUT FOCUSSED AND CLASSIFIED ON A DIFFERENT
REMARK 900 AREA OF THE MAP
REMARK 900 RELATED ID: 6F1V RELATED DB: PDB
REMARK 900 COORDINATES OF DIFFERENT REGION OF THE COMPLEX
REMARK 900 RELATED ID: EMD-4171 RELATED DB: EMDB
REMARK 900 MAP OF THE SAME REGION, FOCUSSED AND CLASSIFIED USING A DIFFERENT
REMARK 900 AREA OF THE MAP
REMARK 900 RELATED ID: 6F1Y RELATED DB: PDB
REMARK 900 COORDINATES FOR DIFFERENT PART OF THE COMPLEX
REMARK 900 RELATED ID: EMD-4172 RELATED DB: EMDB
REMARK 900 ROADBLOCK-1 REGION OF THE DYNEIN TAIL/DYNACTIN/BICDR1 COMPLEX
DBREF 6F1Z o 1 612 UNP Q13409 DC1I2_HUMAN 1 612
DBREF 6F1Z p 1 612 UNP Q13409 DC1I2_HUMAN 1 612
DBREF 6F1Z s 1 96 UNP Q9NP97 DLRB1_HUMAN 1 96
DBREF 6F1Z t 1 96 UNP Q9NP97 DLRB1_HUMAN 1 96
SEQADV 6F1Z SER o 484 UNP Q13409 THR 484 CONFLICT
SEQADV 6F1Z GLY o 499 UNP Q13409 ASP 499 CONFLICT
SEQADV 6F1Z SER p 484 UNP Q13409 THR 484 CONFLICT
SEQADV 6F1Z GLY p 499 UNP Q13409 ASP 499 CONFLICT
SEQRES 1 o 612 MET SER ASP LYS SER GLU LEU LYS ALA GLU LEU GLU ARG
SEQRES 2 o 612 LYS LYS GLN ARG LEU ALA GLN ILE ARG GLU GLU LYS LYS
SEQRES 3 o 612 ARG LYS GLU GLU GLU ARG LYS LYS LYS GLU THR ASP GLN
SEQRES 4 o 612 LYS LYS GLU ALA VAL ALA PRO VAL GLN GLU GLU SER ASP
SEQRES 5 o 612 LEU GLU LYS LYS ARG ARG GLU ALA GLU ALA LEU LEU GLN
SEQRES 6 o 612 SER MET GLY LEU THR PRO GLU SER PRO ILE VAL PRO PRO
SEQRES 7 o 612 PRO MET SER PRO SER SER LYS SER VAL SER THR PRO SER
SEQRES 8 o 612 GLU ALA GLY SER GLN ASP SER GLY ASP GLY ALA VAL GLY
SEQRES 9 o 612 SER ARG ARG GLY PRO ILE LYS LEU GLY MET ALA LYS ILE
SEQRES 10 o 612 THR GLN VAL ASP PHE PRO PRO ARG GLU ILE VAL THR TYR
SEQRES 11 o 612 THR LYS GLU THR GLN THR PRO VAL MET ALA GLN PRO LYS
SEQRES 12 o 612 GLU ASP GLU GLU GLU ASP ASP ASP VAL VAL ALA PRO LYS
SEQRES 13 o 612 PRO PRO ILE GLU PRO GLU GLU GLU LYS THR LEU LYS LYS
SEQRES 14 o 612 ASP GLU GLU ASN ASP SER LYS ALA PRO PRO HIS GLU LEU
SEQRES 15 o 612 THR GLU GLU GLU LYS GLN GLN ILE LEU HIS SER GLU GLU
SEQRES 16 o 612 PHE LEU SER PHE PHE ASP HIS SER THR ARG ILE VAL GLU
SEQRES 17 o 612 ARG ALA LEU SER GLU GLN ILE ASN ILE PHE PHE ASP TYR
SEQRES 18 o 612 SER GLY ARG ASP LEU GLU ASP LYS GLU GLY GLU ILE GLN
SEQRES 19 o 612 ALA GLY ALA LYS LEU SER LEU ASN ARG GLN PHE PHE ASP
SEQRES 20 o 612 GLU ARG TRP SER LYS HIS ARG VAL VAL SER CYS LEU ASP
SEQRES 21 o 612 TRP SER SER GLN TYR PRO GLU LEU LEU VAL ALA SER TYR
SEQRES 22 o 612 ASN ASN ASN GLU ASP ALA PRO HIS GLU PRO ASP GLY VAL
SEQRES 23 o 612 ALA LEU VAL TRP ASN MET LYS TYR LYS LYS THR THR PRO
SEQRES 24 o 612 GLU TYR VAL PHE HIS CYS GLN SER ALA VAL MET SER ALA
SEQRES 25 o 612 THR PHE ALA LYS PHE HIS PRO ASN LEU VAL VAL GLY GLY
SEQRES 26 o 612 THR TYR SER GLY GLN ILE VAL LEU TRP ASP ASN ARG SER
SEQRES 27 o 612 ASN LYS ARG THR PRO VAL GLN ARG THR PRO LEU SER ALA
SEQRES 28 o 612 ALA ALA HIS THR HIS PRO VAL TYR CYS VAL ASN VAL VAL
SEQRES 29 o 612 GLY THR GLN ASN ALA HIS ASN LEU ILE SER ILE SER THR
SEQRES 30 o 612 ASP GLY LYS ILE CYS SER TRP SER LEU ASP MET LEU SER
SEQRES 31 o 612 HIS PRO GLN ASP SER MET GLU LEU VAL HIS LYS GLN SER
SEQRES 32 o 612 LYS ALA VAL ALA VAL THR SER MET SER PHE PRO VAL GLY
SEQRES 33 o 612 ASP VAL ASN ASN PHE VAL VAL GLY SER GLU GLU GLY SER
SEQRES 34 o 612 VAL TYR THR ALA CYS ARG HIS GLY SER LYS ALA GLY ILE
SEQRES 35 o 612 SER GLU MET PHE GLU GLY HIS GLN GLY PRO ILE THR GLY
SEQRES 36 o 612 ILE HIS CYS HIS ALA ALA VAL GLY ALA VAL ASP PHE SER
SEQRES 37 o 612 HIS LEU PHE VAL THR SER SER PHE ASP TRP THR VAL LYS
SEQRES 38 o 612 LEU TRP SER THR LYS ASN ASN LYS PRO LEU TYR SER PHE
SEQRES 39 o 612 GLU ASP ASN ALA GLY TYR VAL TYR ASP VAL MET TRP SER
SEQRES 40 o 612 PRO THR HIS PRO ALA LEU PHE ALA CYS VAL ASP GLY MET
SEQRES 41 o 612 GLY ARG LEU ASP LEU TRP ASN LEU ASN ASN ASP THR GLU
SEQRES 42 o 612 VAL PRO THR ALA SER ILE SER VAL GLU GLY ASN PRO ALA
SEQRES 43 o 612 LEU ASN ARG VAL ARG TRP THR HIS SER GLY ARG GLU ILE
SEQRES 44 o 612 ALA VAL GLY ASP SER GLU GLY GLN ILE VAL ILE TYR ASP
SEQRES 45 o 612 VAL GLY GLU GLN ILE ALA VAL PRO ARG ASN ASP GLU TRP
SEQRES 46 o 612 ALA ARG PHE GLY ARG THR LEU ALA GLU ILE ASN ALA ASN
SEQRES 47 o 612 ARG ALA ASP ALA GLU GLU GLU ALA ALA THR ARG ILE PRO
SEQRES 48 o 612 ALA
SEQRES 1 p 612 MET SER ASP LYS SER GLU LEU LYS ALA GLU LEU GLU ARG
SEQRES 2 p 612 LYS LYS GLN ARG LEU ALA GLN ILE ARG GLU GLU LYS LYS
SEQRES 3 p 612 ARG LYS GLU GLU GLU ARG LYS LYS LYS GLU THR ASP GLN
SEQRES 4 p 612 LYS LYS GLU ALA VAL ALA PRO VAL GLN GLU GLU SER ASP
SEQRES 5 p 612 LEU GLU LYS LYS ARG ARG GLU ALA GLU ALA LEU LEU GLN
SEQRES 6 p 612 SER MET GLY LEU THR PRO GLU SER PRO ILE VAL PRO PRO
SEQRES 7 p 612 PRO MET SER PRO SER SER LYS SER VAL SER THR PRO SER
SEQRES 8 p 612 GLU ALA GLY SER GLN ASP SER GLY ASP GLY ALA VAL GLY
SEQRES 9 p 612 SER ARG ARG GLY PRO ILE LYS LEU GLY MET ALA LYS ILE
SEQRES 10 p 612 THR GLN VAL ASP PHE PRO PRO ARG GLU ILE VAL THR TYR
SEQRES 11 p 612 THR LYS GLU THR GLN THR PRO VAL MET ALA GLN PRO LYS
SEQRES 12 p 612 GLU ASP GLU GLU GLU ASP ASP ASP VAL VAL ALA PRO LYS
SEQRES 13 p 612 PRO PRO ILE GLU PRO GLU GLU GLU LYS THR LEU LYS LYS
SEQRES 14 p 612 ASP GLU GLU ASN ASP SER LYS ALA PRO PRO HIS GLU LEU
SEQRES 15 p 612 THR GLU GLU GLU LYS GLN GLN ILE LEU HIS SER GLU GLU
SEQRES 16 p 612 PHE LEU SER PHE PHE ASP HIS SER THR ARG ILE VAL GLU
SEQRES 17 p 612 ARG ALA LEU SER GLU GLN ILE ASN ILE PHE PHE ASP TYR
SEQRES 18 p 612 SER GLY ARG ASP LEU GLU ASP LYS GLU GLY GLU ILE GLN
SEQRES 19 p 612 ALA GLY ALA LYS LEU SER LEU ASN ARG GLN PHE PHE ASP
SEQRES 20 p 612 GLU ARG TRP SER LYS HIS ARG VAL VAL SER CYS LEU ASP
SEQRES 21 p 612 TRP SER SER GLN TYR PRO GLU LEU LEU VAL ALA SER TYR
SEQRES 22 p 612 ASN ASN ASN GLU ASP ALA PRO HIS GLU PRO ASP GLY VAL
SEQRES 23 p 612 ALA LEU VAL TRP ASN MET LYS TYR LYS LYS THR THR PRO
SEQRES 24 p 612 GLU TYR VAL PHE HIS CYS GLN SER ALA VAL MET SER ALA
SEQRES 25 p 612 THR PHE ALA LYS PHE HIS PRO ASN LEU VAL VAL GLY GLY
SEQRES 26 p 612 THR TYR SER GLY GLN ILE VAL LEU TRP ASP ASN ARG SER
SEQRES 27 p 612 ASN LYS ARG THR PRO VAL GLN ARG THR PRO LEU SER ALA
SEQRES 28 p 612 ALA ALA HIS THR HIS PRO VAL TYR CYS VAL ASN VAL VAL
SEQRES 29 p 612 GLY THR GLN ASN ALA HIS ASN LEU ILE SER ILE SER THR
SEQRES 30 p 612 ASP GLY LYS ILE CYS SER TRP SER LEU ASP MET LEU SER
SEQRES 31 p 612 HIS PRO GLN ASP SER MET GLU LEU VAL HIS LYS GLN SER
SEQRES 32 p 612 LYS ALA VAL ALA VAL THR SER MET SER PHE PRO VAL GLY
SEQRES 33 p 612 ASP VAL ASN ASN PHE VAL VAL GLY SER GLU GLU GLY SER
SEQRES 34 p 612 VAL TYR THR ALA CYS ARG HIS GLY SER LYS ALA GLY ILE
SEQRES 35 p 612 SER GLU MET PHE GLU GLY HIS GLN GLY PRO ILE THR GLY
SEQRES 36 p 612 ILE HIS CYS HIS ALA ALA VAL GLY ALA VAL ASP PHE SER
SEQRES 37 p 612 HIS LEU PHE VAL THR SER SER PHE ASP TRP THR VAL LYS
SEQRES 38 p 612 LEU TRP SER THR LYS ASN ASN LYS PRO LEU TYR SER PHE
SEQRES 39 p 612 GLU ASP ASN ALA GLY TYR VAL TYR ASP VAL MET TRP SER
SEQRES 40 p 612 PRO THR HIS PRO ALA LEU PHE ALA CYS VAL ASP GLY MET
SEQRES 41 p 612 GLY ARG LEU ASP LEU TRP ASN LEU ASN ASN ASP THR GLU
SEQRES 42 p 612 VAL PRO THR ALA SER ILE SER VAL GLU GLY ASN PRO ALA
SEQRES 43 p 612 LEU ASN ARG VAL ARG TRP THR HIS SER GLY ARG GLU ILE
SEQRES 44 p 612 ALA VAL GLY ASP SER GLU GLY GLN ILE VAL ILE TYR ASP
SEQRES 45 p 612 VAL GLY GLU GLN ILE ALA VAL PRO ARG ASN ASP GLU TRP
SEQRES 46 p 612 ALA ARG PHE GLY ARG THR LEU ALA GLU ILE ASN ALA ASN
SEQRES 47 p 612 ARG ALA ASP ALA GLU GLU GLU ALA ALA THR ARG ILE PRO
SEQRES 48 p 612 ALA
SEQRES 1 s 96 MET ALA GLU VAL GLU GLU THR LEU LYS ARG LEU GLN SER
SEQRES 2 s 96 GLN LYS GLY VAL GLN GLY ILE ILE VAL VAL ASN THR GLU
SEQRES 3 s 96 GLY ILE PRO ILE LYS SER THR MET ASP ASN PRO THR THR
SEQRES 4 s 96 THR GLN TYR ALA SER LEU MET HIS SER PHE ILE LEU LYS
SEQRES 5 s 96 ALA ARG SER THR VAL ARG ASP ILE ASP PRO GLN ASN ASP
SEQRES 6 s 96 LEU THR PHE LEU ARG ILE ARG SER LYS LYS ASN GLU ILE
SEQRES 7 s 96 MET VAL ALA PRO ASP LYS ASP TYR PHE LEU ILE VAL ILE
SEQRES 8 s 96 GLN ASN PRO THR GLU
SEQRES 1 t 96 MET ALA GLU VAL GLU GLU THR LEU LYS ARG LEU GLN SER
SEQRES 2 t 96 GLN LYS GLY VAL GLN GLY ILE ILE VAL VAL ASN THR GLU
SEQRES 3 t 96 GLY ILE PRO ILE LYS SER THR MET ASP ASN PRO THR THR
SEQRES 4 t 96 THR GLN TYR ALA SER LEU MET HIS SER PHE ILE LEU LYS
SEQRES 5 t 96 ALA ARG SER THR VAL ARG ASP ILE ASP PRO GLN ASN ASP
SEQRES 6 t 96 LEU THR PHE LEU ARG ILE ARG SER LYS LYS ASN GLU ILE
SEQRES 7 t 96 MET VAL ALA PRO ASP LYS ASP TYR PHE LEU ILE VAL ILE
SEQRES 8 t 96 GLN ASN PRO THR GLU
HELIX 1 AA1 THR o 183 HIS o 192 1 10
HELIX 2 AA2 GLU o 195 ALA o 210 1 16
HELIX 3 AA3 LYS p 187 SER p 193 1 7
HELIX 4 AA4 GLU p 195 LEU p 211 1 17
HELIX 5 AA5 VAL s 4 LEU s 11 1 8
HELIX 6 AA6 ASP s 35 ASP s 61 1 27
HELIX 7 AA7 VAL t 4 SER t 13 1 10
HELIX 8 AA8 ASP t 35 ASP t 61 1 27
SHEET 1 AA1 8 VAL s 17 ILE s 20 0
SHEET 2 AA1 8 PHE s 87 GLN s 92 -1 O ILE s 91 N GLY s 19
SHEET 3 AA1 8 GLU s 77 PRO s 82 -1 N GLU s 77 O GLN s 92
SHEET 4 AA1 8 LEU s 66 SER s 73 -1 N LEU s 69 O VAL s 80
SHEET 5 AA1 8 LEU t 66 SER t 73 -1 O ARG t 72 N PHE s 68
SHEET 6 AA1 8 GLU t 77 VAL t 80 -1 O VAL t 80 N LEU t 69
SHEET 7 AA1 8 ILE t 89 GLN t 92 -1 O GLN t 92 N GLU t 77
SHEET 8 AA1 8 VAL t 17 GLY t 19 -1 N GLN t 18 O ILE t 91
CRYST1 1.000 1.000 1.000 90.00 90.00 90.00 P 1 1
ORIGX1 1.000000 0.000000 0.000000 0.00000
ORIGX2 0.000000 1.000000 0.000000 0.00000
ORIGX3 0.000000 0.000000 1.000000 0.00000
SCALE1 1.000000 0.000000 0.000000 0.00000
SCALE2 0.000000 1.000000 0.000000 0.00000
SCALE3 0.000000 0.000000 1.000000 0.00000
(ATOM LINES ARE NOT SHOWN.)
END
