HEADER TRANSPORT PROTEIN 08-SEP-19 6U9E
TITLE STRUCTURE OF PDPA-VGRG COMPLEX, LIDLESS
COMPND MOL_ID: 1;
COMPND 2 MOLECULE: PDPA;
COMPND 3 CHAIN: A, C, E;
COMPND 4 ENGINEERED: YES;
COMPND 5 MOL_ID: 2;
COMPND 6 MOLECULE: VGRG;
COMPND 7 CHAIN: B, D, F;
COMPND 8 ENGINEERED: YES
SOURCE MOL_ID: 1;
SOURCE 2 ORGANISM_SCIENTIFIC: FRANCISELLA NOVICIDA;
SOURCE 3 ORGANISM_TAXID: 264;
SOURCE 4 GENE: PDPA;
SOURCE 5 EXPRESSION_SYSTEM: ESCHERICHIA COLI;
SOURCE 6 EXPRESSION_SYSTEM_TAXID: 562;
SOURCE 7 MOL_ID: 2;
SOURCE 8 ORGANISM_SCIENTIFIC: FRANCISELLA NOVICIDA;
SOURCE 9 ORGANISM_TAXID: 264;
SOURCE 10 GENE: B4919_03525;
SOURCE 11 EXPRESSION_SYSTEM: ESCHERICHIA COLI;
SOURCE 12 EXPRESSION_SYSTEM_TAXID: 562
KEYWDS T6SS CENTRAL SPIKE, COMPLEX, TRANSPORT PROTEIN
EXPDTA ELECTRON MICROSCOPY
AUTHOR X.YANG,D.L.CLEMENS,B.-Y.LEE,Y.CUI,Z.H.ZHOU,M.A.HORWITZ
REVDAT 3 20-MAR-24 6U9E 1 REMARK
REVDAT 2 05-MAY-21 6U9E 1 JRNL
REVDAT 1 23-OCT-19 6U9E 0
JRNL AUTH X.YANG,D.L.CLEMENS,B.Y.LEE,Y.CUI,Z.H.ZHOU,M.A.HORWITZ
JRNL TITL ATOMIC STRUCTURE OF THE FRANCISELLA T6SS CENTRAL SPIKE
JRNL TITL 2 REVEALS A UNIQUE ALPHA-HELICAL LID AND A PUTATIVE CARGO.
JRNL REF STRUCTURE V. 27 1811 2019
JRNL REFN ISSN 0969-2126
JRNL PMID 31677891
JRNL DOI 10.1016/J.STR.2019.10.007
REMARK 2
REMARK 2 RESOLUTION. 4.21 ANGSTROMS.
REMARK 3
REMARK 3 REFINEMENT.
REMARK 3 SOFTWARE PACKAGES : NULL
REMARK 3 RECONSTRUCTION SCHEMA : NULL
REMARK 3
REMARK 3 EM MAP-MODEL FITTING AND REFINEMENT
REMARK 3 PDB ENTRY : NULL
REMARK 3 REFINEMENT SPACE : REAL
REMARK 3 REFINEMENT PROTOCOL : AB INITIO MODEL
REMARK 3 REFINEMENT TARGET : NULL
REMARK 3 OVERALL ANISOTROPIC B VALUE : NULL
REMARK 3
REMARK 3 FITTING PROCEDURE : NULL
REMARK 3
REMARK 3 EM IMAGE RECONSTRUCTION STATISTICS
REMARK 3 NOMINAL PIXEL SIZE (ANGSTROMS) : NULL
REMARK 3 ACTUAL PIXEL SIZE (ANGSTROMS) : NULL
REMARK 3 EFFECTIVE RESOLUTION (ANGSTROMS) : 4.210
REMARK 3 NUMBER OF PARTICLES : 16889
REMARK 3 CTF CORRECTION METHOD : PHASE FLIPPING ONLY
REMARK 3
REMARK 3 EM RECONSTRUCTION MAGNIFICATION CALIBRATION: NULL
REMARK 3
REMARK 3 OTHER DETAILS: NULL
REMARK 4
REMARK 4 6U9E COMPLIES WITH FORMAT V. 3.30, 13-JUL-11
REMARK 100
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 09-SEP-19.
REMARK 100 THE DEPOSITION ID IS D_1000244231.
REMARK 245
REMARK 245 EXPERIMENTAL DETAILS
REMARK 245 RECONSTRUCTION METHOD : SINGLE PARTICLE
REMARK 245 SPECIMEN TYPE : NULL
REMARK 245
REMARK 245 ELECTRON MICROSCOPE SAMPLE
REMARK 245 SAMPLE TYPE : PARTICLE
REMARK 245 PARTICLE TYPE : POINT
REMARK 245 NAME OF SAMPLE : PDPA-VGRG COMPLEX
REMARK 245 SAMPLE CONCENTRATION (MG ML-1) : NULL
REMARK 245 SAMPLE SUPPORT DETAILS : UNSPECIFIED
REMARK 245 SAMPLE VITRIFICATION DETAILS : NULL
REMARK 245 SAMPLE BUFFER : NULL
REMARK 245 PH : 7.50
REMARK 245 SAMPLE DETAILS : NULL
REMARK 245
REMARK 245 DATA ACQUISITION
REMARK 245 DATE OF EXPERIMENT : NULL
REMARK 245 NUMBER OF MICROGRAPHS-IMAGES : NULL
REMARK 245 TEMPERATURE (KELVIN) : NULL
REMARK 245 MICROSCOPE MODEL : FEI TITAN KRIOS
REMARK 245 DETECTOR TYPE : GATAN K2 SUMMIT (4K X 4K)
REMARK 245 MINIMUM DEFOCUS (NM) : NULL
REMARK 245 MAXIMUM DEFOCUS (NM) : NULL
REMARK 245 MINIMUM TILT ANGLE (DEGREES) : NULL
REMARK 245 MAXIMUM TILT ANGLE (DEGREES) : NULL
REMARK 245 NOMINAL CS : NULL
REMARK 245 IMAGING MODE : BRIGHT FIELD
REMARK 245 ELECTRON DOSE (ELECTRONS NM**-2) : 4700.00
REMARK 245 ILLUMINATION MODE : FLOOD BEAM
REMARK 245 NOMINAL MAGNIFICATION : NULL
REMARK 245 CALIBRATED MAGNIFICATION : NULL
REMARK 245 SOURCE : FIELD EMISSION GUN
REMARK 245 ACCELERATION VOLTAGE (KV) : 300
REMARK 245 IMAGING DETAILS : NULL
REMARK 247
REMARK 247 ELECTRON MICROSCOPY
REMARK 247 THE COORDINATES IN THIS ENTRY WERE GENERATED FROM ELECTRON
REMARK 247 MICROSCOPY DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE
REMARK 247 THAT CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES
REMARK 247 ON THESE RECORDS ARE MEANINGLESS EXCEPT FOR THE CALCULATION
REMARK 247 OF THE STRUCTURE FACTORS.
REMARK 300
REMARK 300 BIOMOLECULE: 1
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON
REMARK 300 BURIED SURFACE AREA.
REMARK 350
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS
REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.
REMARK 350
REMARK 350 BIOMOLECULE: 1
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: HEXAMERIC
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, C, E, B, D, F
REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000
REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000
REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000
REMARK 465
REMARK 465 MISSING RESIDUES
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)
REMARK 465
REMARK 465 M RES C SSSEQI
REMARK 465 MET A 1
REMARK 465 ILE A 2
REMARK 465 ALA A 3
REMARK 465 VAL A 4
REMARK 465 LYS A 5
REMARK 465 ASP A 6
REMARK 465 ILE A 7
REMARK 465 THR A 8
REMARK 465 ASP A 9
REMARK 465 LEU A 10
REMARK 465 ASN A 11
REMARK 465 ILE A 12
REMARK 465 GLN A 13
REMARK 465 ASP A 14
REMARK 465 ILE A 15
REMARK 465 ILE A 16
REMARK 465 SER A 17
REMARK 465 GLN A 18
REMARK 465 LEU A 19
REMARK 465 THR A 20
REMARK 465 SER A 21
REMARK 465 GLU A 22
REMARK 465 VAL A 23
REMARK 465 ILE A 24
REMARK 465 ASN A 25
REMARK 465 GLY A 26
REMARK 465 ASP A 27
REMARK 465 THR A 28
REMARK 465 THR A 29
REMARK 465 PRO A 30
REMARK 465 SER A 31
REMARK 465 SER A 32
REMARK 465 ALA A 33
REMARK 465 LYS A 34
REMARK 465 PHE A 35
REMARK 465 ALA A 36
REMARK 465 CYS A 37
REMARK 465 GLU A 38
REMARK 465 ILE A 39
REMARK 465 ASN A 40
REMARK 465 SER A 41
REMARK 465 TYR A 42
REMARK 465 ILE A 43
REMARK 465 ILE A 44
REMARK 465 ASN A 45
REMARK 465 TYR A 46
REMARK 465 ASN A 47
REMARK 465 LEU A 48
REMARK 465 SER A 49
REMARK 465 ASN A 50
REMARK 465 ILE A 51
REMARK 465 ASN A 52
REMARK 465 LEU A 53
REMARK 465 ILE A 54
REMARK 465 ASN A 55
REMARK 465 THR A 56
REMARK 465 GLN A 57
REMARK 465 LEU A 58
REMARK 465 LYS A 59
REMARK 465 ASN A 60
REMARK 465 THR A 61
REMARK 465 LYS A 62
REMARK 465 ILE A 63
REMARK 465 LEU A 64
REMARK 465 TYR A 65
REMARK 465 ARG A 66
REMARK 465 LYS A 67
REMARK 465 GLY A 68
REMARK 465 LEU A 69
REMARK 465 ILE A 70
REMARK 465 SER A 71
REMARK 465 LYS A 72
REMARK 465 LEU A 73
REMARK 465 ASP A 74
REMARK 465 TYR A 75
REMARK 465 GLU A 76
REMARK 465 LYS A 77
REMARK 465 TYR A 78
REMARK 465 LYS A 79
REMARK 465 ARG A 80
REMARK 465 TYR A 81
REMARK 465 CYS A 82
REMARK 465 ILE A 83
REMARK 465 ILE A 84
REMARK 465 SER A 85
REMARK 465 ARG A 86
REMARK 465 PHE A 87
REMARK 465 LYS A 88
REMARK 465 ASN A 89
REMARK 465 ASN A 90
REMARK 465 ILE A 91
REMARK 465 ASP A 92
REMARK 465 GLU A 93
REMARK 465 PHE A 94
REMARK 465 ILE A 95
REMARK 465 LEU A 96
REMARK 465 TYR A 97
REMARK 465 PHE A 98
REMARK 465 SER A 99
REMARK 465 THR A 100
REMARK 465 ASN A 101
REMARK 465 TYR A 102
REMARK 465 LYS A 103
REMARK 465 ASP A 104
REMARK 465 SER A 105
REMARK 465 GLN A 106
REMARK 465 SER A 107
REMARK 465 LEU A 108
REMARK 465 LYS A 109
REMARK 465 ILE A 110
REMARK 465 ALA A 111
REMARK 465 ILE A 112
REMARK 465 LYS A 113
REMARK 465 GLU A 114
REMARK 465 LEU A 115
REMARK 465 GLN A 116
REMARK 465 ASN A 117
REMARK 465 SER A 118
REMARK 465 CYS A 119
REMARK 465 SER A 120
REMARK 465 SER A 121
REMARK 465 SER A 122
REMARK 465 LEU A 123
REMARK 465 ILE A 124
REMARK 465 LEU A 125
REMARK 465 GLU A 126
REMARK 465 LEU A 127
REMARK 465 PRO A 128
REMARK 465 HIS A 129
REMARK 465 ASP A 130
REMARK 465 TYR A 131
REMARK 465 ILE A 132
REMARK 465 ARG A 133
REMARK 465 LYS A 134
REMARK 465 ILE A 135
REMARK 465 ASP A 136
REMARK 465 VAL A 137
REMARK 465 LEU A 138
REMARK 465 LEU A 139
REMARK 465 THR A 140
REMARK 465 SER A 141
REMARK 465 ILE A 142
REMARK 465 ASP A 143
REMARK 465 SER A 144
REMARK 465 ALA A 145
REMARK 465 ILE A 146
REMARK 465 GLN A 147
REMARK 465 ARG A 148
REMARK 465 SER A 149
REMARK 465 SER A 150
REMARK 465 ASP A 151
REMARK 465 LEU A 152
REMARK 465 ASN A 153
REMARK 465 LYS A 154
REMARK 465 THR A 155
REMARK 465 ILE A 156
REMARK 465 ILE A 157
REMARK 465 LYS A 158
REMARK 465 GLN A 159
REMARK 465 LEU A 160
REMARK 465 ASN A 161
REMARK 465 LYS A 162
REMARK 465 LEU A 163
REMARK 465 ARG A 164
REMARK 465 SER A 165
REMARK 465 SER A 166
REMARK 465 LEU A 167
REMARK 465 SER A 168
REMARK 465 ARG A 169
REMARK 465 TYR A 170
REMARK 465 ILE A 171
REMARK 465 SER A 199
REMARK 465 PHE A 200
REMARK 465 VAL A 201
REMARK 465 SER A 202
REMARK 465 THR A 203
REMARK 465 ARG A 204
REMARK 465 ASN A 205
REMARK 465 LYS A 206
REMARK 465 GLN A 207
REMARK 465 TYR A 208
REMARK 465 PHE A 209
REMARK 465 LYS A 210
REMARK 465 ASN A 271
REMARK 465 PHE A 272
REMARK 465 TYR A 273
REMARK 465 LYS A 274
REMARK 465 LYS A 275
REMARK 465 GLU A 276
REMARK 465 SER A 277
REMARK 465 LYS A 278
REMARK 465 LYS A 279
REMARK 465 ASP A 280
REMARK 465 PHE A 304
REMARK 465 GLU A 305
REMARK 465 TYR A 306
REMARK 465 SER A 307
REMARK 465 ILE A 308
REMARK 465 TYR A 309
REMARK 465 SER A 310
REMARK 465 TYR A 311
REMARK 465 THR A 312
REMARK 465 LYS A 313
REMARK 465 ASN A 314
REMARK 465 VAL A 315
REMARK 465 SER A 316
REMARK 465 SER A 317
REMARK 465 LEU A 582
REMARK 465 HIS A 583
REMARK 465 ASN A 584
REMARK 465 PHE A 585
REMARK 465 HIS A 586
REMARK 465 TYR A 587
REMARK 465 LYS A 588
REMARK 465 SER A 589
REMARK 465 ASP A 590
REMARK 465 SER A 591
REMARK 465 GLU A 592
REMARK 465 SER A 593
REMARK 465 ASP A 594
REMARK 465 VAL A 595
REMARK 465 TYR A 596
REMARK 465 GLU A 597
REMARK 465 LYS A 598
REMARK 465 ILE A 599
REMARK 465 ALA A 600
REMARK 465 PHE A 601
REMARK 465 THR A 602
REMARK 465 LYS A 603
REMARK 465 TYR A 604
REMARK 465 PRO A 605
REMARK 465 SER A 606
REMARK 465 LEU A 607
REMARK 465 THR A 608
REMARK 465 LYS A 818
REMARK 465 GLY A 819
REMARK 465 ASN A 820
REMARK 465 MET C 1
REMARK 465 ILE C 2
REMARK 465 ALA C 3
REMARK 465 VAL C 4
REMARK 465 LYS C 5
REMARK 465 ASP C 6
REMARK 465 ILE C 7
REMARK 465 THR C 8
REMARK 465 ASP C 9
REMARK 465 LEU C 10
REMARK 465 ASN C 11
REMARK 465 ILE C 12
REMARK 465 GLN C 13
REMARK 465 ASP C 14
REMARK 465 ILE C 15
REMARK 465 ILE C 16
REMARK 465 SER C 17
REMARK 465 GLN C 18
REMARK 465 LEU C 19
REMARK 465 THR C 20
REMARK 465 SER C 21
REMARK 465 GLU C 22
REMARK 465 VAL C 23
REMARK 465 ILE C 24
REMARK 465 ASN C 25
REMARK 465 GLY C 26
REMARK 465 ASP C 27
REMARK 465 THR C 28
REMARK 465 THR C 29
REMARK 465 PRO C 30
REMARK 465 SER C 31
REMARK 465 SER C 32
REMARK 465 ALA C 33
REMARK 465 LYS C 34
REMARK 465 PHE C 35
REMARK 465 ALA C 36
REMARK 465 CYS C 37
REMARK 465 GLU C 38
REMARK 465 ILE C 39
REMARK 465 ASN C 40
REMARK 465 SER C 41
REMARK 465 TYR C 42
REMARK 465 ILE C 43
REMARK 465 ILE C 44
REMARK 465 ASN C 45
REMARK 465 TYR C 46
REMARK 465 ASN C 47
REMARK 465 LEU C 48
REMARK 465 SER C 49
REMARK 465 ASN C 50
REMARK 465 ILE C 51
REMARK 465 ASN C 52
REMARK 465 LEU C 53
REMARK 465 ILE C 54
REMARK 465 ASN C 55
REMARK 465 THR C 56
REMARK 465 GLN C 57
REMARK 465 LEU C 58
REMARK 465 LYS C 59
REMARK 465 ASN C 60
REMARK 465 THR C 61
REMARK 465 LYS C 62
REMARK 465 ILE C 63
REMARK 465 LEU C 64
REMARK 465 TYR C 65
REMARK 465 ARG C 66
REMARK 465 LYS C 67
REMARK 465 GLY C 68
REMARK 465 LEU C 69
REMARK 465 ILE C 70
REMARK 465 SER C 71
REMARK 465 LYS C 72
REMARK 465 LEU C 73
REMARK 465 ASP C 74
REMARK 465 TYR C 75
REMARK 465 GLU C 76
REMARK 465 LYS C 77
REMARK 465 TYR C 78
REMARK 465 LYS C 79
REMARK 465 ARG C 80
REMARK 465 TYR C 81
REMARK 465 CYS C 82
REMARK 465 ILE C 83
REMARK 465 ILE C 84
REMARK 465 SER C 85
REMARK 465 ARG C 86
REMARK 465 PHE C 87
REMARK 465 LYS C 88
REMARK 465 ASN C 89
REMARK 465 ASN C 90
REMARK 465 ILE C 91
REMARK 465 ASP C 92
REMARK 465 GLU C 93
REMARK 465 PHE C 94
REMARK 465 ILE C 95
REMARK 465 LEU C 96
REMARK 465 TYR C 97
REMARK 465 PHE C 98
REMARK 465 SER C 99
REMARK 465 THR C 100
REMARK 465 ASN C 101
REMARK 465 TYR C 102
REMARK 465 LYS C 103
REMARK 465 ASP C 104
REMARK 465 SER C 105
REMARK 465 GLN C 106
REMARK 465 SER C 107
REMARK 465 LEU C 108
REMARK 465 LYS C 109
REMARK 465 ILE C 110
REMARK 465 ALA C 111
REMARK 465 ILE C 112
REMARK 465 LYS C 113
REMARK 465 GLU C 114
REMARK 465 LEU C 115
REMARK 465 GLN C 116
REMARK 465 ASN C 117
REMARK 465 SER C 118
REMARK 465 CYS C 119
REMARK 465 SER C 120
REMARK 465 SER C 121
REMARK 465 SER C 122
REMARK 465 LEU C 123
REMARK 465 ILE C 124
REMARK 465 LEU C 125
REMARK 465 GLU C 126
REMARK 465 LEU C 127
REMARK 465 PRO C 128
REMARK 465 HIS C 129
REMARK 465 ASP C 130
REMARK 465 TYR C 131
REMARK 465 ILE C 132
REMARK 465 ARG C 133
REMARK 465 LYS C 134
REMARK 465 ILE C 135
REMARK 465 ASP C 136
REMARK 465 VAL C 137
REMARK 465 LEU C 138
REMARK 465 LEU C 139
REMARK 465 THR C 140
REMARK 465 SER C 141
REMARK 465 ILE C 142
REMARK 465 ASP C 143
REMARK 465 SER C 144
REMARK 465 ALA C 145
REMARK 465 ILE C 146
REMARK 465 GLN C 147
REMARK 465 ARG C 148
REMARK 465 SER C 149
REMARK 465 SER C 150
REMARK 465 ASP C 151
REMARK 465 LEU C 152
REMARK 465 ASN C 153
REMARK 465 LYS C 154
REMARK 465 THR C 155
REMARK 465 ILE C 156
REMARK 465 ILE C 157
REMARK 465 LYS C 158
REMARK 465 GLN C 159
REMARK 465 LEU C 160
REMARK 465 ASN C 161
REMARK 465 LYS C 162
REMARK 465 LEU C 163
REMARK 465 ARG C 164
REMARK 465 SER C 165
REMARK 465 SER C 166
REMARK 465 LEU C 167
REMARK 465 SER C 168
REMARK 465 ARG C 169
REMARK 465 TYR C 170
REMARK 465 ILE C 171
REMARK 465 SER C 199
REMARK 465 PHE C 200
REMARK 465 VAL C 201
REMARK 465 SER C 202
REMARK 465 THR C 203
REMARK 465 ARG C 204
REMARK 465 ASN C 205
REMARK 465 LYS C 206
REMARK 465 GLN C 207
REMARK 465 TYR C 208
REMARK 465 PHE C 209
REMARK 465 LYS C 210
REMARK 465 ASN C 271
REMARK 465 PHE C 272
REMARK 465 TYR C 273
REMARK 465 LYS C 274
REMARK 465 LYS C 275
REMARK 465 GLU C 276
REMARK 465 SER C 277
REMARK 465 LYS C 278
REMARK 465 LYS C 279
REMARK 465 ASP C 280
REMARK 465 PHE C 304
REMARK 465 GLU C 305
REMARK 465 TYR C 306
REMARK 465 SER C 307
REMARK 465 ILE C 308
REMARK 465 TYR C 309
REMARK 465 SER C 310
REMARK 465 TYR C 311
REMARK 465 THR C 312
REMARK 465 LYS C 313
REMARK 465 ASN C 314
REMARK 465 VAL C 315
REMARK 465 SER C 316
REMARK 465 SER C 317
REMARK 465 LEU C 582
REMARK 465 HIS C 583
REMARK 465 ASN C 584
REMARK 465 PHE C 585
REMARK 465 HIS C 586
REMARK 465 TYR C 587
REMARK 465 LYS C 588
REMARK 465 SER C 589
REMARK 465 ASP C 590
REMARK 465 SER C 591
REMARK 465 GLU C 592
REMARK 465 SER C 593
REMARK 465 ASP C 594
REMARK 465 VAL C 595
REMARK 465 TYR C 596
REMARK 465 GLU C 597
REMARK 465 LYS C 598
REMARK 465 ILE C 599
REMARK 465 ALA C 600
REMARK 465 PHE C 601
REMARK 465 THR C 602
REMARK 465 LYS C 603
REMARK 465 TYR C 604
REMARK 465 PRO C 605
REMARK 465 SER C 606
REMARK 465 LEU C 607
REMARK 465 THR C 608
REMARK 465 LYS C 818
REMARK 465 GLY C 819
REMARK 465 ASN C 820
REMARK 465 MET E 1
REMARK 465 ILE E 2
REMARK 465 ALA E 3
REMARK 465 VAL E 4
REMARK 465 LYS E 5
REMARK 465 ASP E 6
REMARK 465 ILE E 7
REMARK 465 THR E 8
REMARK 465 ASP E 9
REMARK 465 LEU E 10
REMARK 465 ASN E 11
REMARK 465 ILE E 12
REMARK 465 GLN E 13
REMARK 465 ASP E 14
REMARK 465 ILE E 15
REMARK 465 ILE E 16
REMARK 465 SER E 17
REMARK 465 GLN E 18
REMARK 465 LEU E 19
REMARK 465 THR E 20
REMARK 465 SER E 21
REMARK 465 GLU E 22
REMARK 465 VAL E 23
REMARK 465 ILE E 24
REMARK 465 ASN E 25
REMARK 465 GLY E 26
REMARK 465 ASP E 27
REMARK 465 THR E 28
REMARK 465 THR E 29
REMARK 465 PRO E 30
REMARK 465 SER E 31
REMARK 465 SER E 32
REMARK 465 ALA E 33
REMARK 465 LYS E 34
REMARK 465 PHE E 35
REMARK 465 ALA E 36
REMARK 465 CYS E 37
REMARK 465 GLU E 38
REMARK 465 ILE E 39
REMARK 465 ASN E 40
REMARK 465 SER E 41
REMARK 465 TYR E 42
REMARK 465 ILE E 43
REMARK 465 ILE E 44
REMARK 465 ASN E 45
REMARK 465 TYR E 46
REMARK 465 ASN E 47
REMARK 465 LEU E 48
REMARK 465 SER E 49
REMARK 465 ASN E 50
REMARK 465 ILE E 51
REMARK 465 ASN E 52
REMARK 465 LEU E 53
REMARK 465 ILE E 54
REMARK 465 ASN E 55
REMARK 465 THR E 56
REMARK 465 GLN E 57
REMARK 465 LEU E 58
REMARK 465 LYS E 59
REMARK 465 ASN E 60
REMARK 465 THR E 61
REMARK 465 LYS E 62
REMARK 465 ILE E 63
REMARK 465 LEU E 64
REMARK 465 TYR E 65
REMARK 465 ARG E 66
REMARK 465 LYS E 67
REMARK 465 GLY E 68
REMARK 465 LEU E 69
REMARK 465 ILE E 70
REMARK 465 SER E 71
REMARK 465 LYS E 72
REMARK 465 LEU E 73
REMARK 465 ASP E 74
REMARK 465 TYR E 75
REMARK 465 GLU E 76
REMARK 465 LYS E 77
REMARK 465 TYR E 78
REMARK 465 LYS E 79
REMARK 465 ARG E 80
REMARK 465 TYR E 81
REMARK 465 CYS E 82
REMARK 465 ILE E 83
REMARK 465 ILE E 84
REMARK 465 SER E 85
REMARK 465 ARG E 86
REMARK 465 PHE E 87
REMARK 465 LYS E 88
REMARK 465 ASN E 89
REMARK 465 ASN E 90
REMARK 465 ILE E 91
REMARK 465 ASP E 92
REMARK 465 GLU E 93
REMARK 465 PHE E 94
REMARK 465 ILE E 95
REMARK 465 LEU E 96
REMARK 465 TYR E 97
REMARK 465 PHE E 98
REMARK 465 SER E 99
REMARK 465 THR E 100
REMARK 465 ASN E 101
REMARK 465 TYR E 102
REMARK 465 LYS E 103
REMARK 465 ASP E 104
REMARK 465 SER E 105
REMARK 465 GLN E 106
REMARK 465 SER E 107
REMARK 465 LEU E 108
REMARK 465 LYS E 109
REMARK 465 ILE E 110
REMARK 465 ALA E 111
REMARK 465 ILE E 112
REMARK 465 LYS E 113
REMARK 465 GLU E 114
REMARK 465 LEU E 115
REMARK 465 GLN E 116
REMARK 465 ASN E 117
REMARK 465 SER E 118
REMARK 465 CYS E 119
REMARK 465 SER E 120
REMARK 465 SER E 121
REMARK 465 SER E 122
REMARK 465 LEU E 123
REMARK 465 ILE E 124
REMARK 465 LEU E 125
REMARK 465 GLU E 126
REMARK 465 LEU E 127
REMARK 465 PRO E 128
REMARK 465 HIS E 129
REMARK 465 ASP E 130
REMARK 465 TYR E 131
REMARK 465 ILE E 132
REMARK 465 ARG E 133
REMARK 465 LYS E 134
REMARK 465 ILE E 135
REMARK 465 ASP E 136
REMARK 465 VAL E 137
REMARK 465 LEU E 138
REMARK 465 LEU E 139
REMARK 465 THR E 140
REMARK 465 SER E 141
REMARK 465 ILE E 142
REMARK 465 ASP E 143
REMARK 465 SER E 144
REMARK 465 ALA E 145
REMARK 465 ILE E 146
REMARK 465 GLN E 147
REMARK 465 ARG E 148
REMARK 465 SER E 149
REMARK 465 SER E 150
REMARK 465 ASP E 151
REMARK 465 LEU E 152
REMARK 465 ASN E 153
REMARK 465 LYS E 154
REMARK 465 THR E 155
REMARK 465 ILE E 156
REMARK 465 ILE E 157
REMARK 465 LYS E 158
REMARK 465 GLN E 159
REMARK 465 LEU E 160
REMARK 465 ASN E 161
REMARK 465 LYS E 162
REMARK 465 LEU E 163
REMARK 465 ARG E 164
REMARK 465 SER E 165
REMARK 465 SER E 166
REMARK 465 LEU E 167
REMARK 465 SER E 168
REMARK 465 ARG E 169
REMARK 465 TYR E 170
REMARK 465 ILE E 171
REMARK 465 SER E 199
REMARK 465 PHE E 200
REMARK 465 VAL E 201
REMARK 465 SER E 202
REMARK 465 THR E 203
REMARK 465 ARG E 204
REMARK 465 ASN E 205
REMARK 465 LYS E 206
REMARK 465 GLN E 207
REMARK 465 TYR E 208
REMARK 465 PHE E 209
REMARK 465 LYS E 210
REMARK 465 ASN E 271
REMARK 465 PHE E 272
REMARK 465 TYR E 273
REMARK 465 LYS E 274
REMARK 465 LYS E 275
REMARK 465 GLU E 276
REMARK 465 SER E 277
REMARK 465 LYS E 278
REMARK 465 LYS E 279
REMARK 465 ASP E 280
REMARK 465 PHE E 304
REMARK 465 GLU E 305
REMARK 465 TYR E 306
REMARK 465 SER E 307
REMARK 465 ILE E 308
REMARK 465 TYR E 309
REMARK 465 SER E 310
REMARK 465 TYR E 311
REMARK 465 THR E 312
REMARK 465 LYS E 313
REMARK 465 ASN E 314
REMARK 465 VAL E 315
REMARK 465 SER E 316
REMARK 465 SER E 317
REMARK 465 LEU E 582
REMARK 465 HIS E 583
REMARK 465 ASN E 584
REMARK 465 PHE E 585
REMARK 465 HIS E 586
REMARK 465 TYR E 587
REMARK 465 LYS E 588
REMARK 465 SER E 589
REMARK 465 ASP E 590
REMARK 465 SER E 591
REMARK 465 GLU E 592
REMARK 465 SER E 593
REMARK 465 ASP E 594
REMARK 465 VAL E 595
REMARK 465 TYR E 596
REMARK 465 GLU E 597
REMARK 465 LYS E 598
REMARK 465 ILE E 599
REMARK 465 ALA E 600
REMARK 465 PHE E 601
REMARK 465 THR E 602
REMARK 465 LYS E 603
REMARK 465 TYR E 604
REMARK 465 PRO E 605
REMARK 465 SER E 606
REMARK 465 LEU E 607
REMARK 465 THR E 608
REMARK 465 LYS E 818
REMARK 465 GLY E 819
REMARK 465 ASN E 820
REMARK 465 MET B -24
REMARK 465 ASP B -23
REMARK 465 TYR B -22
REMARK 465 LYS B -21
REMARK 465 ASP B -20
REMARK 465 ASP B -19
REMARK 465 ASP B -18
REMARK 465 ASP B -17
REMARK 465 LYS B -16
REMARK 465 ASP B -15
REMARK 465 TYR B -14
REMARK 465 LYS B -13
REMARK 465 ASP B -12
REMARK 465 ASP B -11
REMARK 465 ASP B -10
REMARK 465 ASP B -9
REMARK 465 LYS B -8
REMARK 465 ASP B -7
REMARK 465 TYR B -6
REMARK 465 LYS B -5
REMARK 465 ASP B -4
REMARK 465 ASP B -3
REMARK 465 ASP B -2
REMARK 465 ASP B -1
REMARK 465 LYS B 0
REMARK 465 GLY B 1
REMARK 465 SER B 2
REMARK 465 VAL B 136
REMARK 465 ASN B 137
REMARK 465 LEU B 138
REMARK 465 ASN B 139
REMARK 465 ALA B 140
REMARK 465 GLU B 141
REMARK 465 GLY B 142
REMARK 465 LEU B 143
REMARK 465 ASP B 144
REMARK 465 VAL B 145
REMARK 465 ASN B 146
REMARK 465 ILE B 147
REMARK 465 LYS B 148
REMARK 465 GLY B 149
REMARK 465 SER B 150
REMARK 465 VAL B 151
REMARK 465 THR B 152
REMARK 465 ALA B 153
REMARK 465 SER B 154
REMARK 465 ILE B 155
REMARK 465 LYS B 156
REMARK 465 GLY B 157
REMARK 465 SER B 158
REMARK 465 ALA B 159
REMARK 465 ALA B 160
REMARK 465 THR B 161
REMARK 465 MET B 162
REMARK 465 VAL B 163
REMARK 465 GLY B 164
REMARK 465 MET D -24
REMARK 465 ASP D -23
REMARK 465 TYR D -22
REMARK 465 LYS D -21
REMARK 465 ASP D -20
REMARK 465 ASP D -19
REMARK 465 ASP D -18
REMARK 465 ASP D -17
REMARK 465 LYS D -16
REMARK 465 ASP D -15
REMARK 465 TYR D -14
REMARK 465 LYS D -13
REMARK 465 ASP D -12
REMARK 465 ASP D -11
REMARK 465 ASP D -10
REMARK 465 ASP D -9
REMARK 465 LYS D -8
REMARK 465 ASP D -7
REMARK 465 TYR D -6
REMARK 465 LYS D -5
REMARK 465 ASP D -4
REMARK 465 ASP D -3
REMARK 465 ASP D -2
REMARK 465 ASP D -1
REMARK 465 LYS D 0
REMARK 465 GLY D 1
REMARK 465 SER D 2
REMARK 465 VAL D 136
REMARK 465 ASN D 137
REMARK 465 LEU D 138
REMARK 465 ASN D 139
REMARK 465 ALA D 140
REMARK 465 GLU D 141
REMARK 465 GLY D 142
REMARK 465 LEU D 143
REMARK 465 ASP D 144
REMARK 465 VAL D 145
REMARK 465 ASN D 146
REMARK 465 ILE D 147
REMARK 465 LYS D 148
REMARK 465 GLY D 149
REMARK 465 SER D 150
REMARK 465 VAL D 151
REMARK 465 THR D 152
REMARK 465 ALA D 153
REMARK 465 SER D 154
REMARK 465 ILE D 155
REMARK 465 LYS D 156
REMARK 465 GLY D 157
REMARK 465 SER D 158
REMARK 465 ALA D 159
REMARK 465 ALA D 160
REMARK 465 THR D 161
REMARK 465 MET D 162
REMARK 465 VAL D 163
REMARK 465 GLY D 164
REMARK 465 MET F -24
REMARK 465 ASP F -23
REMARK 465 TYR F -22
REMARK 465 LYS F -21
REMARK 465 ASP F -20
REMARK 465 ASP F -19
REMARK 465 ASP F -18
REMARK 465 ASP F -17
REMARK 465 LYS F -16
REMARK 465 ASP F -15
REMARK 465 TYR F -14
REMARK 465 LYS F -13
REMARK 465 ASP F -12
REMARK 465 ASP F -11
REMARK 465 ASP F -10
REMARK 465 ASP F -9
REMARK 465 LYS F -8
REMARK 465 ASP F -7
REMARK 465 TYR F -6
REMARK 465 LYS F -5
REMARK 465 ASP F -4
REMARK 465 ASP F -3
REMARK 465 ASP F -2
REMARK 465 ASP F -1
REMARK 465 LYS F 0
REMARK 465 GLY F 1
REMARK 465 SER F 2
REMARK 465 VAL F 136
REMARK 465 ASN F 137
REMARK 465 LEU F 138
REMARK 465 ASN F 139
REMARK 465 ALA F 140
REMARK 465 GLU F 141
REMARK 465 GLY F 142
REMARK 465 LEU F 143
REMARK 465 ASP F 144
REMARK 465 VAL F 145
REMARK 465 ASN F 146
REMARK 465 ILE F 147
REMARK 465 LYS F 148
REMARK 465 GLY F 149
REMARK 465 SER F 150
REMARK 465 VAL F 151
REMARK 465 THR F 152
REMARK 465 ALA F 153
REMARK 465 SER F 154
REMARK 465 ILE F 155
REMARK 465 LYS F 156
REMARK 465 GLY F 157
REMARK 465 SER F 158
REMARK 465 ALA F 159
REMARK 465 ALA F 160
REMARK 465 THR F 161
REMARK 465 MET F 162
REMARK 465 VAL F 163
REMARK 465 GLY F 164
REMARK 470
REMARK 470 MISSING ATOM
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;
REMARK 470 I=INSERTION CODE):
REMARK 470 M RES CSSEQI ATOMS
REMARK 470 TYR A 173 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 ASN A 174 CG OD1 ND2
REMARK 470 ASN A 175 CG OD1 ND2
REMARK 470 ILE A 198 CG1 CG2 CD1
REMARK 470 TYR A 243 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 ILE A 244 CG1 CG2 CD1
REMARK 470 HIS A 281 CG ND1 CD2 CE1 NE2
REMARK 470 ASN A 510 CG OD1 ND2
REMARK 470 ASP A 511 CG OD1 OD2
REMARK 470 ASP A 512 CG OD1 OD2
REMARK 470 LYS A 513 CG CD CE NZ
REMARK 470 HIS A 609 CG ND1 CD2 CE1 NE2
REMARK 470 TYR C 173 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 ASN C 174 CG OD1 ND2
REMARK 470 ASN C 175 CG OD1 ND2
REMARK 470 ILE C 198 CG1 CG2 CD1
REMARK 470 TYR C 243 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 ILE C 244 CG1 CG2 CD1
REMARK 470 HIS C 281 CG ND1 CD2 CE1 NE2
REMARK 470 ASN C 510 CG OD1 ND2
REMARK 470 ASP C 511 CG OD1 OD2
REMARK 470 ASP C 512 CG OD1 OD2
REMARK 470 LYS C 513 CG CD CE NZ
REMARK 470 HIS C 609 CG ND1 CD2 CE1 NE2
REMARK 470 TYR E 173 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 ASN E 174 CG OD1 ND2
REMARK 470 ASN E 175 CG OD1 ND2
REMARK 470 ILE E 198 CG1 CG2 CD1
REMARK 470 TYR E 243 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 ILE E 244 CG1 CG2 CD1
REMARK 470 HIS E 281 CG ND1 CD2 CE1 NE2
REMARK 470 ASN E 510 CG OD1 ND2
REMARK 470 ASP E 511 CG OD1 OD2
REMARK 470 ASP E 512 CG OD1 OD2
REMARK 470 LYS E 513 CG CD CE NZ
REMARK 470 HIS E 609 CG ND1 CD2 CE1 NE2
REMARK 470 ASP B 82 CG OD1 OD2
REMARK 470 ASN B 130 CG OD1 ND2
REMARK 470 ILE B 132 CG1 CG2 CD1
REMARK 470 LYS B 133 CG CD CE NZ
REMARK 470 ASP B 135 CG OD1 OD2
REMARK 470 ASP D 82 CG OD1 OD2
REMARK 470 ASN D 130 CG OD1 ND2
REMARK 470 ILE D 132 CG1 CG2 CD1
REMARK 470 LYS D 133 CG CD CE NZ
REMARK 470 ASP D 135 CG OD1 OD2
REMARK 470 ASP F 82 CG OD1 OD2
REMARK 470 ASN F 130 CG OD1 ND2
REMARK 470 ILE F 132 CG1 CG2 CD1
REMARK 470 LYS F 133 CG CD CE NZ
REMARK 470 ASP F 135 CG OD1 OD2
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: TORSION ANGLES
REMARK 500
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)
REMARK 500
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400
REMARK 500
REMARK 500 M RES CSSEQI PSI PHI
REMARK 500 ASN A 212 14.11 59.98
REMARK 500 LYS A 217 -158.16 -146.19
REMARK 500 ASN A 218 109.82 -41.92
REMARK 500 LYS A 336 52.59 -95.00
REMARK 500 PHE A 357 71.35 -117.53
REMARK 500 ARG A 386 -168.93 -126.30
REMARK 500 GLN A 421 -169.02 -126.01
REMARK 500 PRO A 443 47.61 -74.85
REMARK 500 PHE A 492 -168.10 -79.92
REMARK 500 PHE A 521 117.08 -163.55
REMARK 500 LEU A 534 -169.47 -124.79
REMARK 500 THR A 536 49.74 -91.73
REMARK 500 SER A 541 -168.92 -127.01
REMARK 500 ASN A 548 30.09 -94.88
REMARK 500 ASP A 555 34.36 -98.61
REMARK 500 LYS A 557 -158.65 -85.94
REMARK 500 SER A 558 151.79 -47.08
REMARK 500 SER A 652 40.46 -104.88
REMARK 500 ALA A 655 -168.94 -125.64
REMARK 500 ASN A 661 48.41 -142.12
REMARK 500 GLU A 671 -3.41 66.98
REMARK 500 GLN A 673 65.33 29.62
REMARK 500 SER A 686 71.04 57.04
REMARK 500 ASP A 689 17.91 59.13
REMARK 500 SER A 706 51.76 -94.25
REMARK 500 ILE A 719 -63.46 -121.66
REMARK 500 ASN A 720 46.73 -88.99
REMARK 500 SER A 721 -165.12 -164.92
REMARK 500 ALA A 722 -159.56 -148.99
REMARK 500 ALA A 761 18.70 59.49
REMARK 500 LYS A 774 -6.61 72.90
REMARK 500 ASN A 776 50.55 -96.95
REMARK 500 MET A 779 62.96 -101.33
REMARK 500 ASN C 212 14.13 59.95
REMARK 500 LYS C 217 -158.11 -146.18
REMARK 500 ASN C 218 109.73 -41.90
REMARK 500 LYS C 336 52.65 -95.08
REMARK 500 PHE C 357 71.39 -117.51
REMARK 500 ARG C 386 -168.91 -126.31
REMARK 500 GLN C 421 -168.98 -125.99
REMARK 500 PRO C 443 47.70 -74.91
REMARK 500 PHE C 492 -168.10 -79.95
REMARK 500 PHE C 521 117.08 -163.57
REMARK 500 LEU C 534 -169.50 -124.82
REMARK 500 THR C 536 49.72 -91.71
REMARK 500 SER C 541 -168.84 -127.12
REMARK 500 ASN C 548 30.05 -94.82
REMARK 500 ASP C 555 34.33 -98.54
REMARK 500 LYS C 557 -158.62 -85.88
REMARK 500 SER C 558 151.75 -47.13
REMARK 500
REMARK 500 THIS ENTRY HAS 126 RAMACHANDRAN OUTLIERS.
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: NON-CIS, NON-TRANS
REMARK 500
REMARK 500 THE FOLLOWING PEPTIDE BONDS DEVIATE SIGNIFICANTLY FROM BOTH
REMARK 500 CIS AND TRANS CONFORMATION. CIS BONDS, IF ANY, ARE LISTED
REMARK 500 ON CISPEP RECORDS. TRANS IS DEFINED AS 180 +/- 30 AND
REMARK 500 CIS IS DEFINED AS 0 +/- 30 DEGREES.
REMARK 500 MODEL OMEGA
REMARK 500 ASN A 218 PRO A 219 -141.81
REMARK 500 PHE A 672 GLN A 673 149.22
REMARK 500 GLU A 674 ASN A 675 -145.71
REMARK 500 ASN A 675 GLY A 676 146.45
REMARK 500 LEU A 715 LYS A 716 145.87
REMARK 500 ASN C 218 PRO C 219 -141.75
REMARK 500 PHE C 672 GLN C 673 149.19
REMARK 500 GLU C 674 ASN C 675 -145.65
REMARK 500 ASN C 675 GLY C 676 146.38
REMARK 500 LEU C 715 LYS C 716 145.83
REMARK 500 ASN E 218 PRO E 219 -141.80
REMARK 500 PHE E 672 GLN E 673 149.19
REMARK 500 GLU E 674 ASN E 675 -145.67
REMARK 500 ASN E 675 GLY E 676 146.46
REMARK 500 LEU E 715 LYS E 716 145.88
REMARK 500 LYS B 87 ILE B 88 149.11
REMARK 500 LYS D 87 ILE D 88 149.02
REMARK 500 LYS F 87 ILE F 88 149.11
REMARK 500
REMARK 500 REMARK: NULL
REMARK 900
REMARK 900 RELATED ENTRIES
REMARK 900 RELATED ID: EMD-20695 RELATED DB: EMDB
REMARK 900 RELATED ID: EMD-20696 RELATED DB: EMDB
REMARK 900 RELATED ID: EMD-20698 RELATED DB: EMDB
DBREF 6U9E A 1 820 UNP Q7X3I9 Q7X3I9_FRANO 1 820
DBREF 6U9E C 1 820 UNP Q7X3I9 Q7X3I9_FRANO 1 820
DBREF 6U9E E 1 820 UNP Q7X3I9 Q7X3I9_FRANO 1 820
DBREF 6U9E B 2 164 UNP Q7X3I8 Q7X3I8_FRANO 2 164
DBREF 6U9E D 2 164 UNP Q7X3I8 Q7X3I8_FRANO 2 164
DBREF 6U9E F 2 164 UNP Q7X3I8 Q7X3I8_FRANO 2 164
SEQADV 6U9E MET B -24 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP B -23 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E TYR B -22 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E LYS B -21 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP B -20 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP B -19 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP B -18 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP B -17 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E LYS B -16 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP B -15 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E TYR B -14 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E LYS B -13 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP B -12 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP B -11 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP B -10 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP B -9 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E LYS B -8 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP B -7 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E TYR B -6 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E LYS B -5 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP B -4 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP B -3 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP B -2 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP B -1 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E LYS B 0 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E GLY B 1 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E MET D -24 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP D -23 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E TYR D -22 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E LYS D -21 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP D -20 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP D -19 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP D -18 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP D -17 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E LYS D -16 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP D -15 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E TYR D -14 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E LYS D -13 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP D -12 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP D -11 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP D -10 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP D -9 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E LYS D -8 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP D -7 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E TYR D -6 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E LYS D -5 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP D -4 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP D -3 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP D -2 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP D -1 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E LYS D 0 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E GLY D 1 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E MET F -24 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP F -23 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E TYR F -22 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E LYS F -21 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP F -20 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP F -19 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP F -18 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP F -17 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E LYS F -16 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP F -15 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E TYR F -14 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E LYS F -13 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP F -12 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP F -11 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP F -10 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP F -9 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E LYS F -8 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP F -7 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E TYR F -6 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E LYS F -5 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP F -4 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP F -3 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP F -2 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E ASP F -1 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E LYS F 0 UNP Q7X3I8 EXPRESSION TAG
SEQADV 6U9E GLY F 1 UNP Q7X3I8 EXPRESSION TAG
SEQRES 1 A 820 MET ILE ALA VAL LYS ASP ILE THR ASP LEU ASN ILE GLN
SEQRES 2 A 820 ASP ILE ILE SER GLN LEU THR SER GLU VAL ILE ASN GLY
SEQRES 3 A 820 ASP THR THR PRO SER SER ALA LYS PHE ALA CYS GLU ILE
SEQRES 4 A 820 ASN SER TYR ILE ILE ASN TYR ASN LEU SER ASN ILE ASN
SEQRES 5 A 820 LEU ILE ASN THR GLN LEU LYS ASN THR LYS ILE LEU TYR
SEQRES 6 A 820 ARG LYS GLY LEU ILE SER LYS LEU ASP TYR GLU LYS TYR
SEQRES 7 A 820 LYS ARG TYR CYS ILE ILE SER ARG PHE LYS ASN ASN ILE
SEQRES 8 A 820 ASP GLU PHE ILE LEU TYR PHE SER THR ASN TYR LYS ASP
SEQRES 9 A 820 SER GLN SER LEU LYS ILE ALA ILE LYS GLU LEU GLN ASN
SEQRES 10 A 820 SER CYS SER SER SER LEU ILE LEU GLU LEU PRO HIS ASP
SEQRES 11 A 820 TYR ILE ARG LYS ILE ASP VAL LEU LEU THR SER ILE ASP
SEQRES 12 A 820 SER ALA ILE GLN ARG SER SER ASP LEU ASN LYS THR ILE
SEQRES 13 A 820 ILE LYS GLN LEU ASN LYS LEU ARG SER SER LEU SER ARG
SEQRES 14 A 820 TYR ILE GLY TYR ASN ASN VAL LEU GLN LYS GLN GLU ILE
SEQRES 15 A 820 THR ILE ASN ILE LYS PRO ILE ASN LYS ASN PHE GLU LEU
SEQRES 16 A 820 GLU ASP ILE SER PHE VAL SER THR ARG ASN LYS GLN TYR
SEQRES 17 A 820 PHE LYS HIS ASN SER LEU THR LEU LYS ASN PRO HIS ILE
SEQRES 18 A 820 GLU LYS LEU GLU VAL CYS GLU ASN ILE TYR GLY ILE ASN
SEQRES 19 A 820 GLY TRP LEU THR PHE ASP LEU ALA TYR ILE ASN ASN HIS
SEQRES 20 A 820 LYS ASP PHE ASN PHE LEU LEU SER PRO ASN GLN PRO ILE
SEQRES 21 A 820 LEU LEU ASP ILE GLN ILE ASN ASP SER PHE ASN PHE TYR
SEQRES 22 A 820 LYS LYS GLU SER LYS LYS ASP HIS HIS LYS ARG THR THR
SEQRES 23 A 820 ARG PHE ILE ALA ILE GLY PHE ASN SER ASN SER ILE ASP
SEQRES 24 A 820 ILE HIS GLU ASN PHE GLU TYR SER ILE TYR SER TYR THR
SEQRES 25 A 820 LYS ASN VAL SER SER GLY VAL LYS LYS PHE LYS ILE GLN
SEQRES 26 A 820 PHE HIS ASP PRO LEU LYS ALA LEU TRP THR LYS HIS LYS
SEQRES 27 A 820 PRO SER TYR ILE ALA LEU ASN LYS SER LEU ASP ASP ILE
SEQRES 28 A 820 PHE LYS ASP ASN PHE PHE PHE ASP SER LEU PHE SER LEU
SEQRES 29 A 820 ASP THR ASN LYS SER ASN ASN LEU LYS ILE ARG ILE PRO
SEQRES 30 A 820 GLN ALA PHE ILE SER THR VAL ASN ARG ASN PHE TYR ASP
SEQRES 31 A 820 PHE PHE ILE GLN GLN LEU GLU GLN ASN LYS CYS TYR LEU
SEQRES 32 A 820 LYS TYR PHE CYS ASP LYS LYS SER GLY LYS VAL SER TYR
SEQRES 33 A 820 HIS VAL VAL ASP GLN VAL ASP ASN ASP LEU GLN ARG ASN
SEQRES 34 A 820 ILE VAL ASN SER ASP GLU ASP LEU LYS ASP LYS LEU SER
SEQRES 35 A 820 PRO TYR ASP ILE SER CYS PHE LYS LYS GLN ILE LEU ILE
SEQRES 36 A 820 SER ASN LYS SER ASN PHE TYR VAL LYS GLU LYS ASN ILE
SEQRES 37 A 820 CYS PRO ASP VAL THR LEU ASN THR GLN ARG LYS GLU ASP
SEQRES 38 A 820 ARG LYS ILE SER ASP THR LEU VAL LYS PRO PHE SER SER
SEQRES 39 A 820 ILE LEU LYS ASP ASN LEU GLN SER VAL GLU TYR ILE GLN
SEQRES 40 A 820 SER ASN ASN ASP ASP LYS GLN GLU ILE ILE THR THR GLY
SEQRES 41 A 820 PHE GLU ILE LEU LEU THR SER ARG ASN THR LEU PRO PHE
SEQRES 42 A 820 LEU ASP THR GLU ILE THR LEU SER LYS LEU ASP ASN ASP
SEQRES 43 A 820 GLN ASN TYR LEU LEU GLY ALA THR ASP ILE LYS SER LEU
SEQRES 44 A 820 TYR ILE SER GLN ARG LYS LEU LEU PHE LYS ARG SER LYS
SEQRES 45 A 820 TYR CYS SER LYS GLN LEU TYR GLU ASN LEU HIS ASN PHE
SEQRES 46 A 820 HIS TYR LYS SER ASP SER GLU SER ASP VAL TYR GLU LYS
SEQRES 47 A 820 ILE ALA PHE THR LYS TYR PRO SER LEU THR HIS ASP ASN
SEQRES 48 A 820 SER ILE THR TYR LYS ILE LYS ASP TYR SER ASN LEU THR
SEQRES 49 A 820 PRO GLU TYR PRO LYS TYR LYS SER PHE SER ASN PHE TYR
SEQRES 50 A 820 ILE ASN GLY ARG ILE THR ILE GLY GLU ASN VAL ASN ASN
SEQRES 51 A 820 ASP SER LYS LYS ALA TYR LYS PHE PHE LYS ASN HIS LYS
SEQRES 52 A 820 PRO GLU GLU SER SER ILE ALA GLU PHE GLN GLU ASN GLY
SEQRES 53 A 820 GLU LYS GLY THR SER ALA ILE LEU ASN SER LYS ALA ASP
SEQRES 54 A 820 ILE LEU TYR ALA ILE GLU ILE ALA LYS GLU MET LEU SER
SEQRES 55 A 820 ASP LYS SER SER ASP LYS PRO ILE ILE TYR LEU PRO LEU
SEQRES 56 A 820 LYS VAL ASN ILE ASN SER ALA ASN ASN GLN PHE ILE PRO
SEQRES 57 A 820 LEU ARG ASN ASP ASP ILE ILE LEU ILE GLU ILE GLN SER
SEQRES 58 A 820 PHE THR LYS GLY GLU ILE ILE GLU LEU ILE SER ASN SER
SEQRES 59 A 820 ALA ILE SER THR LYS LYS ALA GLN GLN GLN LEU LEU GLN
SEQRES 60 A 820 ARG GLN LEU LEU GLY SER LYS GLU ASN CYS GLU MET ALA
SEQRES 61 A 820 TYR THR GLN THR SER ASP SER GLU THR PHE SER LEU THR
SEQRES 62 A 820 GLN VAL ASN GLU ASP CYS GLU ASN SER PHE LEU ILE ASN
SEQRES 63 A 820 ASP LYS LYS GLY ILE PHE LEU ARG TYR LYS SER LYS GLY
SEQRES 64 A 820 ASN
SEQRES 1 C 820 MET ILE ALA VAL LYS ASP ILE THR ASP LEU ASN ILE GLN
SEQRES 2 C 820 ASP ILE ILE SER GLN LEU THR SER GLU VAL ILE ASN GLY
SEQRES 3 C 820 ASP THR THR PRO SER SER ALA LYS PHE ALA CYS GLU ILE
SEQRES 4 C 820 ASN SER TYR ILE ILE ASN TYR ASN LEU SER ASN ILE ASN
SEQRES 5 C 820 LEU ILE ASN THR GLN LEU LYS ASN THR LYS ILE LEU TYR
SEQRES 6 C 820 ARG LYS GLY LEU ILE SER LYS LEU ASP TYR GLU LYS TYR
SEQRES 7 C 820 LYS ARG TYR CYS ILE ILE SER ARG PHE LYS ASN ASN ILE
SEQRES 8 C 820 ASP GLU PHE ILE LEU TYR PHE SER THR ASN TYR LYS ASP
SEQRES 9 C 820 SER GLN SER LEU LYS ILE ALA ILE LYS GLU LEU GLN ASN
SEQRES 10 C 820 SER CYS SER SER SER LEU ILE LEU GLU LEU PRO HIS ASP
SEQRES 11 C 820 TYR ILE ARG LYS ILE ASP VAL LEU LEU THR SER ILE ASP
SEQRES 12 C 820 SER ALA ILE GLN ARG SER SER ASP LEU ASN LYS THR ILE
SEQRES 13 C 820 ILE LYS GLN LEU ASN LYS LEU ARG SER SER LEU SER ARG
SEQRES 14 C 820 TYR ILE GLY TYR ASN ASN VAL LEU GLN LYS GLN GLU ILE
SEQRES 15 C 820 THR ILE ASN ILE LYS PRO ILE ASN LYS ASN PHE GLU LEU
SEQRES 16 C 820 GLU ASP ILE SER PHE VAL SER THR ARG ASN LYS GLN TYR
SEQRES 17 C 820 PHE LYS HIS ASN SER LEU THR LEU LYS ASN PRO HIS ILE
SEQRES 18 C 820 GLU LYS LEU GLU VAL CYS GLU ASN ILE TYR GLY ILE ASN
SEQRES 19 C 820 GLY TRP LEU THR PHE ASP LEU ALA TYR ILE ASN ASN HIS
SEQRES 20 C 820 LYS ASP PHE ASN PHE LEU LEU SER PRO ASN GLN PRO ILE
SEQRES 21 C 820 LEU LEU ASP ILE GLN ILE ASN ASP SER PHE ASN PHE TYR
SEQRES 22 C 820 LYS LYS GLU SER LYS LYS ASP HIS HIS LYS ARG THR THR
SEQRES 23 C 820 ARG PHE ILE ALA ILE GLY PHE ASN SER ASN SER ILE ASP
SEQRES 24 C 820 ILE HIS GLU ASN PHE GLU TYR SER ILE TYR SER TYR THR
SEQRES 25 C 820 LYS ASN VAL SER SER GLY VAL LYS LYS PHE LYS ILE GLN
SEQRES 26 C 820 PHE HIS ASP PRO LEU LYS ALA LEU TRP THR LYS HIS LYS
SEQRES 27 C 820 PRO SER TYR ILE ALA LEU ASN LYS SER LEU ASP ASP ILE
SEQRES 28 C 820 PHE LYS ASP ASN PHE PHE PHE ASP SER LEU PHE SER LEU
SEQRES 29 C 820 ASP THR ASN LYS SER ASN ASN LEU LYS ILE ARG ILE PRO
SEQRES 30 C 820 GLN ALA PHE ILE SER THR VAL ASN ARG ASN PHE TYR ASP
SEQRES 31 C 820 PHE PHE ILE GLN GLN LEU GLU GLN ASN LYS CYS TYR LEU
SEQRES 32 C 820 LYS TYR PHE CYS ASP LYS LYS SER GLY LYS VAL SER TYR
SEQRES 33 C 820 HIS VAL VAL ASP GLN VAL ASP ASN ASP LEU GLN ARG ASN
SEQRES 34 C 820 ILE VAL ASN SER ASP GLU ASP LEU LYS ASP LYS LEU SER
SEQRES 35 C 820 PRO TYR ASP ILE SER CYS PHE LYS LYS GLN ILE LEU ILE
SEQRES 36 C 820 SER ASN LYS SER ASN PHE TYR VAL LYS GLU LYS ASN ILE
SEQRES 37 C 820 CYS PRO ASP VAL THR LEU ASN THR GLN ARG LYS GLU ASP
SEQRES 38 C 820 ARG LYS ILE SER ASP THR LEU VAL LYS PRO PHE SER SER
SEQRES 39 C 820 ILE LEU LYS ASP ASN LEU GLN SER VAL GLU TYR ILE GLN
SEQRES 40 C 820 SER ASN ASN ASP ASP LYS GLN GLU ILE ILE THR THR GLY
SEQRES 41 C 820 PHE GLU ILE LEU LEU THR SER ARG ASN THR LEU PRO PHE
SEQRES 42 C 820 LEU ASP THR GLU ILE THR LEU SER LYS LEU ASP ASN ASP
SEQRES 43 C 820 GLN ASN TYR LEU LEU GLY ALA THR ASP ILE LYS SER LEU
SEQRES 44 C 820 TYR ILE SER GLN ARG LYS LEU LEU PHE LYS ARG SER LYS
SEQRES 45 C 820 TYR CYS SER LYS GLN LEU TYR GLU ASN LEU HIS ASN PHE
SEQRES 46 C 820 HIS TYR LYS SER ASP SER GLU SER ASP VAL TYR GLU LYS
SEQRES 47 C 820 ILE ALA PHE THR LYS TYR PRO SER LEU THR HIS ASP ASN
SEQRES 48 C 820 SER ILE THR TYR LYS ILE LYS ASP TYR SER ASN LEU THR
SEQRES 49 C 820 PRO GLU TYR PRO LYS TYR LYS SER PHE SER ASN PHE TYR
SEQRES 50 C 820 ILE ASN GLY ARG ILE THR ILE GLY GLU ASN VAL ASN ASN
SEQRES 51 C 820 ASP SER LYS LYS ALA TYR LYS PHE PHE LYS ASN HIS LYS
SEQRES 52 C 820 PRO GLU GLU SER SER ILE ALA GLU PHE GLN GLU ASN GLY
SEQRES 53 C 820 GLU LYS GLY THR SER ALA ILE LEU ASN SER LYS ALA ASP
SEQRES 54 C 820 ILE LEU TYR ALA ILE GLU ILE ALA LYS GLU MET LEU SER
SEQRES 55 C 820 ASP LYS SER SER ASP LYS PRO ILE ILE TYR LEU PRO LEU
SEQRES 56 C 820 LYS VAL ASN ILE ASN SER ALA ASN ASN GLN PHE ILE PRO
SEQRES 57 C 820 LEU ARG ASN ASP ASP ILE ILE LEU ILE GLU ILE GLN SER
SEQRES 58 C 820 PHE THR LYS GLY GLU ILE ILE GLU LEU ILE SER ASN SER
SEQRES 59 C 820 ALA ILE SER THR LYS LYS ALA GLN GLN GLN LEU LEU GLN
SEQRES 60 C 820 ARG GLN LEU LEU GLY SER LYS GLU ASN CYS GLU MET ALA
SEQRES 61 C 820 TYR THR GLN THR SER ASP SER GLU THR PHE SER LEU THR
SEQRES 62 C 820 GLN VAL ASN GLU ASP CYS GLU ASN SER PHE LEU ILE ASN
SEQRES 63 C 820 ASP LYS LYS GLY ILE PHE LEU ARG TYR LYS SER LYS GLY
SEQRES 64 C 820 ASN
SEQRES 1 E 820 MET ILE ALA VAL LYS ASP ILE THR ASP LEU ASN ILE GLN
SEQRES 2 E 820 ASP ILE ILE SER GLN LEU THR SER GLU VAL ILE ASN GLY
SEQRES 3 E 820 ASP THR THR PRO SER SER ALA LYS PHE ALA CYS GLU ILE
SEQRES 4 E 820 ASN SER TYR ILE ILE ASN TYR ASN LEU SER ASN ILE ASN
SEQRES 5 E 820 LEU ILE ASN THR GLN LEU LYS ASN THR LYS ILE LEU TYR
SEQRES 6 E 820 ARG LYS GLY LEU ILE SER LYS LEU ASP TYR GLU LYS TYR
SEQRES 7 E 820 LYS ARG TYR CYS ILE ILE SER ARG PHE LYS ASN ASN ILE
SEQRES 8 E 820 ASP GLU PHE ILE LEU TYR PHE SER THR ASN TYR LYS ASP
SEQRES 9 E 820 SER GLN SER LEU LYS ILE ALA ILE LYS GLU LEU GLN ASN
SEQRES 10 E 820 SER CYS SER SER SER LEU ILE LEU GLU LEU PRO HIS ASP
SEQRES 11 E 820 TYR ILE ARG LYS ILE ASP VAL LEU LEU THR SER ILE ASP
SEQRES 12 E 820 SER ALA ILE GLN ARG SER SER ASP LEU ASN LYS THR ILE
SEQRES 13 E 820 ILE LYS GLN LEU ASN LYS LEU ARG SER SER LEU SER ARG
SEQRES 14 E 820 TYR ILE GLY TYR ASN ASN VAL LEU GLN LYS GLN GLU ILE
SEQRES 15 E 820 THR ILE ASN ILE LYS PRO ILE ASN LYS ASN PHE GLU LEU
SEQRES 16 E 820 GLU ASP ILE SER PHE VAL SER THR ARG ASN LYS GLN TYR
SEQRES 17 E 820 PHE LYS HIS ASN SER LEU THR LEU LYS ASN PRO HIS ILE
SEQRES 18 E 820 GLU LYS LEU GLU VAL CYS GLU ASN ILE TYR GLY ILE ASN
SEQRES 19 E 820 GLY TRP LEU THR PHE ASP LEU ALA TYR ILE ASN ASN HIS
SEQRES 20 E 820 LYS ASP PHE ASN PHE LEU LEU SER PRO ASN GLN PRO ILE
SEQRES 21 E 820 LEU LEU ASP ILE GLN ILE ASN ASP SER PHE ASN PHE TYR
SEQRES 22 E 820 LYS LYS GLU SER LYS LYS ASP HIS HIS LYS ARG THR THR
SEQRES 23 E 820 ARG PHE ILE ALA ILE GLY PHE ASN SER ASN SER ILE ASP
SEQRES 24 E 820 ILE HIS GLU ASN PHE GLU TYR SER ILE TYR SER TYR THR
SEQRES 25 E 820 LYS ASN VAL SER SER GLY VAL LYS LYS PHE LYS ILE GLN
SEQRES 26 E 820 PHE HIS ASP PRO LEU LYS ALA LEU TRP THR LYS HIS LYS
SEQRES 27 E 820 PRO SER TYR ILE ALA LEU ASN LYS SER LEU ASP ASP ILE
SEQRES 28 E 820 PHE LYS ASP ASN PHE PHE PHE ASP SER LEU PHE SER LEU
SEQRES 29 E 820 ASP THR ASN LYS SER ASN ASN LEU LYS ILE ARG ILE PRO
SEQRES 30 E 820 GLN ALA PHE ILE SER THR VAL ASN ARG ASN PHE TYR ASP
SEQRES 31 E 820 PHE PHE ILE GLN GLN LEU GLU GLN ASN LYS CYS TYR LEU
SEQRES 32 E 820 LYS TYR PHE CYS ASP LYS LYS SER GLY LYS VAL SER TYR
SEQRES 33 E 820 HIS VAL VAL ASP GLN VAL ASP ASN ASP LEU GLN ARG ASN
SEQRES 34 E 820 ILE VAL ASN SER ASP GLU ASP LEU LYS ASP LYS LEU SER
SEQRES 35 E 820 PRO TYR ASP ILE SER CYS PHE LYS LYS GLN ILE LEU ILE
SEQRES 36 E 820 SER ASN LYS SER ASN PHE TYR VAL LYS GLU LYS ASN ILE
SEQRES 37 E 820 CYS PRO ASP VAL THR LEU ASN THR GLN ARG LYS GLU ASP
SEQRES 38 E 820 ARG LYS ILE SER ASP THR LEU VAL LYS PRO PHE SER SER
SEQRES 39 E 820 ILE LEU LYS ASP ASN LEU GLN SER VAL GLU TYR ILE GLN
SEQRES 40 E 820 SER ASN ASN ASP ASP LYS GLN GLU ILE ILE THR THR GLY
SEQRES 41 E 820 PHE GLU ILE LEU LEU THR SER ARG ASN THR LEU PRO PHE
SEQRES 42 E 820 LEU ASP THR GLU ILE THR LEU SER LYS LEU ASP ASN ASP
SEQRES 43 E 820 GLN ASN TYR LEU LEU GLY ALA THR ASP ILE LYS SER LEU
SEQRES 44 E 820 TYR ILE SER GLN ARG LYS LEU LEU PHE LYS ARG SER LYS
SEQRES 45 E 820 TYR CYS SER LYS GLN LEU TYR GLU ASN LEU HIS ASN PHE
SEQRES 46 E 820 HIS TYR LYS SER ASP SER GLU SER ASP VAL TYR GLU LYS
SEQRES 47 E 820 ILE ALA PHE THR LYS TYR PRO SER LEU THR HIS ASP ASN
SEQRES 48 E 820 SER ILE THR TYR LYS ILE LYS ASP TYR SER ASN LEU THR
SEQRES 49 E 820 PRO GLU TYR PRO LYS TYR LYS SER PHE SER ASN PHE TYR
SEQRES 50 E 820 ILE ASN GLY ARG ILE THR ILE GLY GLU ASN VAL ASN ASN
SEQRES 51 E 820 ASP SER LYS LYS ALA TYR LYS PHE PHE LYS ASN HIS LYS
SEQRES 52 E 820 PRO GLU GLU SER SER ILE ALA GLU PHE GLN GLU ASN GLY
SEQRES 53 E 820 GLU LYS GLY THR SER ALA ILE LEU ASN SER LYS ALA ASP
SEQRES 54 E 820 ILE LEU TYR ALA ILE GLU ILE ALA LYS GLU MET LEU SER
SEQRES 55 E 820 ASP LYS SER SER ASP LYS PRO ILE ILE TYR LEU PRO LEU
SEQRES 56 E 820 LYS VAL ASN ILE ASN SER ALA ASN ASN GLN PHE ILE PRO
SEQRES 57 E 820 LEU ARG ASN ASP ASP ILE ILE LEU ILE GLU ILE GLN SER
SEQRES 58 E 820 PHE THR LYS GLY GLU ILE ILE GLU LEU ILE SER ASN SER
SEQRES 59 E 820 ALA ILE SER THR LYS LYS ALA GLN GLN GLN LEU LEU GLN
SEQRES 60 E 820 ARG GLN LEU LEU GLY SER LYS GLU ASN CYS GLU MET ALA
SEQRES 61 E 820 TYR THR GLN THR SER ASP SER GLU THR PHE SER LEU THR
SEQRES 62 E 820 GLN VAL ASN GLU ASP CYS GLU ASN SER PHE LEU ILE ASN
SEQRES 63 E 820 ASP LYS LYS GLY ILE PHE LEU ARG TYR LYS SER LYS GLY
SEQRES 64 E 820 ASN
SEQRES 1 B 189 MET ASP TYR LYS ASP ASP ASP ASP LYS ASP TYR LYS ASP
SEQRES 2 B 189 ASP ASP ASP LYS ASP TYR LYS ASP ASP ASP ASP LYS GLY
SEQRES 3 B 189 SER LYS ALA ASP HIS ILE PHE ASN LEU GLU GLU GLN GLY
SEQRES 4 B 189 LEU LEU ILE ASP ILE LYS ASP ASP SER LYS GLY CYS THR
SEQRES 5 B 189 THR LYS LEU GLU SER SER GLY LYS ILE THR HIS ASN ALA
SEQRES 6 B 189 THR GLU SER ILE GLU SER SER ALA ASP LYS GLN ILE ILE
SEQRES 7 B 189 GLU ASN VAL LYS ASP SER LYS ILE SER ILE THR GLU LYS
SEQRES 8 B 189 GLU ILE LEU LEU ALA THR LYS LYS SER SER ILE MET LEU
SEQRES 9 B 189 SER GLU ASP LYS ILE VAL ILE LYS ILE GLY ASN SER LEU
SEQRES 10 B 189 ILE ILE LEU ASP ASP SER ASN ILE SER LEU GLU SER ALA
SEQRES 11 B 189 THR ILE ASN ILE LYS SER SER ALA ASN ILE ASN ILE GLN
SEQRES 12 B 189 ALA SER GLN ASN ILE ASP ILE LYS SER LEU ASN ASN SER
SEQRES 13 B 189 ILE LYS ALA ASP VAL ASN LEU ASN ALA GLU GLY LEU ASP
SEQRES 14 B 189 VAL ASN ILE LYS GLY SER VAL THR ALA SER ILE LYS GLY
SEQRES 15 B 189 SER ALA ALA THR MET VAL GLY
SEQRES 1 D 189 MET ASP TYR LYS ASP ASP ASP ASP LYS ASP TYR LYS ASP
SEQRES 2 D 189 ASP ASP ASP LYS ASP TYR LYS ASP ASP ASP ASP LYS GLY
SEQRES 3 D 189 SER LYS ALA ASP HIS ILE PHE ASN LEU GLU GLU GLN GLY
SEQRES 4 D 189 LEU LEU ILE ASP ILE LYS ASP ASP SER LYS GLY CYS THR
SEQRES 5 D 189 THR LYS LEU GLU SER SER GLY LYS ILE THR HIS ASN ALA
SEQRES 6 D 189 THR GLU SER ILE GLU SER SER ALA ASP LYS GLN ILE ILE
SEQRES 7 D 189 GLU ASN VAL LYS ASP SER LYS ILE SER ILE THR GLU LYS
SEQRES 8 D 189 GLU ILE LEU LEU ALA THR LYS LYS SER SER ILE MET LEU
SEQRES 9 D 189 SER GLU ASP LYS ILE VAL ILE LYS ILE GLY ASN SER LEU
SEQRES 10 D 189 ILE ILE LEU ASP ASP SER ASN ILE SER LEU GLU SER ALA
SEQRES 11 D 189 THR ILE ASN ILE LYS SER SER ALA ASN ILE ASN ILE GLN
SEQRES 12 D 189 ALA SER GLN ASN ILE ASP ILE LYS SER LEU ASN ASN SER
SEQRES 13 D 189 ILE LYS ALA ASP VAL ASN LEU ASN ALA GLU GLY LEU ASP
SEQRES 14 D 189 VAL ASN ILE LYS GLY SER VAL THR ALA SER ILE LYS GLY
SEQRES 15 D 189 SER ALA ALA THR MET VAL GLY
SEQRES 1 F 189 MET ASP TYR LYS ASP ASP ASP ASP LYS ASP TYR LYS ASP
SEQRES 2 F 189 ASP ASP ASP LYS ASP TYR LYS ASP ASP ASP ASP LYS GLY
SEQRES 3 F 189 SER LYS ALA ASP HIS ILE PHE ASN LEU GLU GLU GLN GLY
SEQRES 4 F 189 LEU LEU ILE ASP ILE LYS ASP ASP SER LYS GLY CYS THR
SEQRES 5 F 189 THR LYS LEU GLU SER SER GLY LYS ILE THR HIS ASN ALA
SEQRES 6 F 189 THR GLU SER ILE GLU SER SER ALA ASP LYS GLN ILE ILE
SEQRES 7 F 189 GLU ASN VAL LYS ASP SER LYS ILE SER ILE THR GLU LYS
SEQRES 8 F 189 GLU ILE LEU LEU ALA THR LYS LYS SER SER ILE MET LEU
SEQRES 9 F 189 SER GLU ASP LYS ILE VAL ILE LYS ILE GLY ASN SER LEU
SEQRES 10 F 189 ILE ILE LEU ASP ASP SER ASN ILE SER LEU GLU SER ALA
SEQRES 11 F 189 THR ILE ASN ILE LYS SER SER ALA ASN ILE ASN ILE GLN
SEQRES 12 F 189 ALA SER GLN ASN ILE ASP ILE LYS SER LEU ASN ASN SER
SEQRES 13 F 189 ILE LYS ALA ASP VAL ASN LEU ASN ALA GLU GLY LEU ASP
SEQRES 14 F 189 VAL ASN ILE LYS GLY SER VAL THR ALA SER ILE LYS GLY
SEQRES 15 F 189 SER ALA ALA THR MET VAL GLY
HELIX 1 AA1 ASP A 249 LEU A 254 1 6
HELIX 2 AA2 ASP A 328 THR A 335 1 8
HELIX 3 AA3 SER A 347 LYS A 353 1 7
HELIX 4 AA4 ASN A 387 GLN A 398 1 12
HELIX 5 AA5 ASP A 423 ARG A 428 1 6
HELIX 6 AA6 SER A 571 ASN A 581 1 11
HELIX 7 AA7 SER A 621 LEU A 623 5 3
HELIX 8 AA8 ALA A 697 LEU A 701 5 5
HELIX 9 AA9 GLY A 772 ASN A 776 5 5
HELIX 10 AB1 ASP C 249 LEU C 254 1 6
HELIX 11 AB2 ASP C 328 THR C 335 1 8
HELIX 12 AB3 SER C 347 LYS C 353 1 7
HELIX 13 AB4 ASN C 387 GLN C 398 1 12
HELIX 14 AB5 ASP C 423 ARG C 428 1 6
HELIX 15 AB6 SER C 571 ASN C 581 1 11
HELIX 16 AB7 SER C 621 LEU C 623 5 3
HELIX 17 AB8 ALA C 697 LEU C 701 5 5
HELIX 18 AB9 GLY C 772 ASN C 776 5 5
HELIX 19 AC1 ASP E 249 LEU E 254 1 6
HELIX 20 AC2 ASP E 328 THR E 335 1 8
HELIX 21 AC3 SER E 347 LYS E 353 1 7
HELIX 22 AC4 ASN E 387 GLN E 398 1 12
HELIX 23 AC5 ASP E 423 ARG E 428 1 6
HELIX 24 AC6 SER E 571 ASN E 581 1 11
HELIX 25 AC7 SER E 621 LEU E 623 5 3
HELIX 26 AC8 ALA E 697 LEU E 701 5 5
HELIX 27 AC9 GLY E 772 ASN E 776 5 5
SHEET 1 AA1 3 LYS A 179 PRO A 188 0
SHEET 2 AA1 3 ILE A 260 SER A 269 -1 O ASP A 263 N ASN A 185
SHEET 3 AA1 3 LYS A 283 ILE A 291 -1 O THR A 286 N ILE A 266
SHEET 1 AA2 5 ILE A 233 ASN A 234 0
SHEET 2 AA2 5 LYS A 223 GLU A 228 -1 N CYS A 227 O ASN A 234
SHEET 3 AA2 5 TRP A 236 LEU A 241 -1 O TRP A 236 N GLU A 225
SHEET 4 AA2 5 LYS A 320 GLN A 325 -1 O LYS A 320 N LEU A 241
SHEET 5 AA2 5 ILE A 300 HIS A 301 -1 N HIS A 301 O LYS A 321
SHEET 1 AA3 6 ILE A 233 ASN A 234 0
SHEET 2 AA3 6 LYS A 223 GLU A 228 -1 N CYS A 227 O ASN A 234
SHEET 3 AA3 6 LEU A 559 LYS A 569 -1 O PHE A 568 N LEU A 224
SHEET 4 AA3 6 ILE A 613 ASP A 619 -1 O LYS A 616 N SER A 562
SHEET 5 AA3 6 ILE A 523 THR A 526 -1 N ILE A 523 O ILE A 617
SHEET 6 AA3 6 LYS A 451 LEU A 454 -1 N ILE A 453 O LEU A 524
SHEET 1 AA4 2 ILE A 342 LEU A 344 0
SHEET 2 AA4 2 GLN A 378 PHE A 380 -1 O ALA A 379 N ALA A 343
SHEET 1 AA5 2 SER A 363 ASP A 365 0
SHEET 2 AA5 2 SER A 415 HIS A 417 1 O TYR A 416 N ASP A 365
SHEET 1 AA6 2 PHE A 461 TYR A 462 0
SHEET 2 AA6 2 LYS A 490 PRO A 491 1 O LYS A 490 N TYR A 462
SHEET 1 AA7 3 GLU A 480 ASP A 481 0
SHEET 2 AA7 3 LYS A 466 ILE A 468 -1 N ASN A 467 O GLU A 480
SHEET 3 AA7 3 ASN A 499 LEU A 500 1 O ASN A 499 N LYS A 466
SHEET 1 AA8 3 TYR A 637 GLY A 640 0
SHEET 2 AA8 3 ILE A 735 SER A 741 -1 O ILE A 737 N ILE A 638
SHEET 3 AA8 3 LYS A 744 LEU A 750 -1 O GLU A 746 N GLU A 738
SHEET 1 AA9 2 TYR A 692 GLU A 695 0
SHEET 2 AA9 2 ILE A 710 LEU A 713 -1 O ILE A 711 N ILE A 694
SHEET 1 AB1 2 TYR A 781 GLN A 783 0
SHEET 2 AB1 2 GLU A 788 PHE A 790 -1 O THR A 789 N THR A 782
SHEET 1 AB2 2 GLU A 800 SER A 802 0
SHEET 2 AB2 2 ARG A 814 LYS A 816 -1 O LYS A 816 N GLU A 800
SHEET 1 AB3 3 LYS C 179 PRO C 188 0
SHEET 2 AB3 3 ILE C 260 SER C 269 -1 O ASP C 263 N ASN C 185
SHEET 3 AB3 3 LYS C 283 ILE C 291 -1 O THR C 286 N ILE C 266
SHEET 1 AB4 8 ILE C 300 HIS C 301 0
SHEET 2 AB4 8 LYS C 320 GLN C 325 -1 O LYS C 321 N HIS C 301
SHEET 3 AB4 8 ILE C 233 LEU C 241 -1 N LEU C 241 O LYS C 320
SHEET 4 AB4 8 LYS C 223 GLU C 228 -1 N GLU C 225 O TRP C 236
SHEET 5 AB4 8 LEU C 559 LYS C 569 -1 O PHE C 568 N LEU C 224
SHEET 6 AB4 8 ILE C 613 ASP C 619 -1 O LYS C 616 N SER C 562
SHEET 7 AB4 8 ILE C 523 THR C 526 -1 N ILE C 523 O ILE C 617
SHEET 8 AB4 8 LYS C 451 LEU C 454 -1 N ILE C 453 O LEU C 524
SHEET 1 AB5 2 ILE C 342 LEU C 344 0
SHEET 2 AB5 2 GLN C 378 PHE C 380 -1 O ALA C 379 N ALA C 343
SHEET 1 AB6 2 SER C 363 ASP C 365 0
SHEET 2 AB6 2 SER C 415 HIS C 417 1 O TYR C 416 N ASP C 365
SHEET 1 AB7 2 PHE C 461 TYR C 462 0
SHEET 2 AB7 2 LYS C 490 PRO C 491 1 O LYS C 490 N TYR C 462
SHEET 1 AB8 3 GLU C 480 ASP C 481 0
SHEET 2 AB8 3 LYS C 466 ILE C 468 -1 N ASN C 467 O GLU C 480
SHEET 3 AB8 3 ASN C 499 LEU C 500 1 O ASN C 499 N LYS C 466
SHEET 1 AB9 3 TYR C 637 GLY C 640 0
SHEET 2 AB9 3 ILE C 735 SER C 741 -1 O ILE C 737 N ILE C 638
SHEET 3 AB9 3 LYS C 744 LEU C 750 -1 O GLU C 746 N GLU C 738
SHEET 1 AC1 2 TYR C 692 GLU C 695 0
SHEET 2 AC1 2 ILE C 710 LEU C 713 -1 O ILE C 711 N ILE C 694
SHEET 1 AC2 2 TYR C 781 GLN C 783 0
SHEET 2 AC2 2 GLU C 788 PHE C 790 -1 O THR C 789 N THR C 782
SHEET 1 AC3 2 GLU C 800 SER C 802 0
SHEET 2 AC3 2 ARG C 814 LYS C 816 -1 O LYS C 816 N GLU C 800
SHEET 1 AC4 3 LYS E 179 PRO E 188 0
SHEET 2 AC4 3 ILE E 260 SER E 269 -1 O ASP E 263 N ASN E 185
SHEET 3 AC4 3 LYS E 283 ILE E 291 -1 O THR E 286 N ILE E 266
SHEET 1 AC5 8 ILE E 300 HIS E 301 0
SHEET 2 AC5 8 LYS E 320 GLN E 325 -1 O LYS E 321 N HIS E 301
SHEET 3 AC5 8 ILE E 233 LEU E 241 -1 N LEU E 241 O LYS E 320
SHEET 4 AC5 8 LYS E 223 GLU E 228 -1 N GLU E 225 O TRP E 236
SHEET 5 AC5 8 LEU E 559 LYS E 569 -1 O PHE E 568 N LEU E 224
SHEET 6 AC5 8 ILE E 613 ASP E 619 -1 O LYS E 616 N SER E 562
SHEET 7 AC5 8 ILE E 523 THR E 526 -1 N ILE E 523 O ILE E 617
SHEET 8 AC5 8 LYS E 451 LEU E 454 -1 N ILE E 453 O LEU E 524
SHEET 1 AC6 2 ILE E 342 LEU E 344 0
SHEET 2 AC6 2 GLN E 378 PHE E 380 -1 O ALA E 379 N ALA E 343
SHEET 1 AC7 2 SER E 363 ASP E 365 0
SHEET 2 AC7 2 SER E 415 HIS E 417 1 O TYR E 416 N ASP E 365
SHEET 1 AC8 2 PHE E 461 TYR E 462 0
SHEET 2 AC8 2 LYS E 490 PRO E 491 1 O LYS E 490 N TYR E 462
SHEET 1 AC9 3 GLU E 480 ASP E 481 0
SHEET 2 AC9 3 LYS E 466 ILE E 468 -1 N ASN E 467 O GLU E 480
SHEET 3 AC9 3 ASN E 499 LEU E 500 1 O ASN E 499 N LYS E 466
SHEET 1 AD1 3 TYR E 637 GLY E 640 0
SHEET 2 AD1 3 ILE E 735 SER E 741 -1 O ILE E 737 N ILE E 638
SHEET 3 AD1 3 LYS E 744 LEU E 750 -1 O GLU E 746 N GLU E 738
SHEET 1 AD2 2 TYR E 692 GLU E 695 0
SHEET 2 AD2 2 ILE E 710 LEU E 713 -1 O ILE E 711 N ILE E 694
SHEET 1 AD3 2 TYR E 781 GLN E 783 0
SHEET 2 AD3 2 GLU E 788 PHE E 790 -1 O THR E 789 N THR E 782
SHEET 1 AD4 2 GLU E 800 SER E 802 0
SHEET 2 AD4 2 ARG E 814 LYS E 816 -1 O LYS E 816 N GLU E 800
SHEET 1 AD5 3 ASP B 5 HIS B 6 0
SHEET 2 AD5 3 GLY B 14 LYS B 20 -1 O LYS B 20 N ASP B 5
SHEET 3 AD5 3 GLY B 25 GLU B 31 -1 O THR B 28 N ILE B 17
SHEET 1 AD6 5 LYS D 35 ILE D 36 0
SHEET 2 AD6 5 SER B 43 SER B 47 1 N GLU B 45 O ILE D 36
SHEET 3 AD6 5 GLN F 51 ASN F 55 1 O ILE F 53 N ILE B 44
SHEET 4 AD6 5 LYS F 60 ILE F 63 -1 O ILE F 61 N GLU F 54
SHEET 5 AD6 5 ILE F 68 ALA F 71 -1 O LEU F 69 N SER F 62
SHEET 1 AD7 5 ILE B 68 ALA B 71 0
SHEET 2 AD7 5 LYS B 60 ILE B 63 -1 N SER B 62 O LEU B 69
SHEET 3 AD7 5 GLN B 51 ASN B 55 -1 N GLU B 54 O ILE B 61
SHEET 4 AD7 5 SER D 43 SER D 47 1 O ILE D 44 N ILE B 53
SHEET 5 AD7 5 LYS F 35 ILE F 36 1 O ILE F 36 N GLU D 45
SHEET 1 AD8 8 SER B 76 LEU B 79 0
SHEET 2 AD8 8 ILE B 84 LYS B 87 -1 O LYS B 87 N SER B 76
SHEET 3 AD8 8 LEU B 92 LEU B 95 -1 O LEU B 95 N ILE B 84
SHEET 4 AD8 8 ASN B 99 GLU B 103 -1 O SER B 101 N ILE B 94
SHEET 5 AD8 8 THR F 106 ILE F 109 1 O ASN F 108 N ILE B 100
SHEET 6 AD8 8 ILE D 115 ILE D 117 1 N ASN D 116 O ILE F 109
SHEET 7 AD8 8 ILE B 123 ILE B 125 1 N ASP B 124 O ILE D 117
SHEET 8 AD8 8 SER F 131 ILE F 132 1 O ILE F 132 N ILE B 123
SHEET 1 AD9 8 SER B 131 ILE B 132 0
SHEET 2 AD9 8 ILE D 123 ILE D 125 1 O ILE D 123 N ILE B 132
SHEET 3 AD9 8 ILE F 115 ILE F 117 1 O ILE F 117 N ASP D 124
SHEET 4 AD9 8 THR B 106 ILE B 109 1 N ILE B 107 O ASN F 116
SHEET 5 AD9 8 ASN D 99 GLU D 103 1 O ILE D 100 N ASN B 108
SHEET 6 AD9 8 LEU D 92 LEU D 95 -1 N ILE D 94 O SER D 101
SHEET 7 AD9 8 ILE D 84 LYS D 87 -1 N ILE D 84 O LEU D 95
SHEET 8 AD9 8 SER D 76 LEU D 79 -1 N SER D 76 O LYS D 87
SHEET 1 AE1 8 SER D 131 ILE D 132 0
SHEET 2 AE1 8 ILE F 123 ILE F 125 1 O ILE F 123 N ILE D 132
SHEET 3 AE1 8 ILE B 115 ILE B 117 1 N ILE B 117 O ASP F 124
SHEET 4 AE1 8 THR D 106 ILE D 109 1 O ILE D 109 N ASN B 116
SHEET 5 AE1 8 ASN F 99 GLU F 103 1 O ILE F 100 N ASN D 108
SHEET 6 AE1 8 LEU F 92 LEU F 95 -1 N ILE F 94 O SER F 101
SHEET 7 AE1 8 ILE F 84 LYS F 87 -1 N ILE F 84 O LEU F 95
SHEET 8 AE1 8 SER F 76 LEU F 79 -1 N SER F 76 O LYS F 87
SHEET 1 AE2 3 ASP D 5 HIS D 6 0
SHEET 2 AE2 3 GLY D 14 LYS D 20 -1 O LYS D 20 N ASP D 5
SHEET 3 AE2 3 GLY D 25 GLU D 31 -1 O THR D 28 N ILE D 17
SHEET 1 AE3 4 ILE D 68 ALA D 71 0
SHEET 2 AE3 4 LYS D 60 ILE D 63 -1 N SER D 62 O LEU D 69
SHEET 3 AE3 4 GLN D 51 ASN D 55 -1 N GLU D 54 O ILE D 61
SHEET 4 AE3 4 SER F 43 SER F 47 1 O SER F 46 N ILE D 53
SHEET 1 AE4 3 ASP F 5 HIS F 6 0
SHEET 2 AE4 3 GLY F 14 LYS F 20 -1 O LYS F 20 N ASP F 5
SHEET 3 AE4 3 GLY F 25 GLU F 31 -1 O THR F 28 N ILE F 17
CISPEP 1 ASN A 175 VAL A 176 0 13.23
CISPEP 2 ALA A 242 TYR A 243 0 3.84
CISPEP 3 ILE A 244 ASN A 245 0 -3.73
CISPEP 4 LYS A 410 SER A 411 0 -7.14
CISPEP 5 ASN A 510 ASP A 511 0 -3.42
CISPEP 6 LYS A 678 GLY A 679 0 -19.70
CISPEP 7 ASN C 175 VAL C 176 0 13.10
CISPEP 8 ALA C 242 TYR C 243 0 3.81
CISPEP 9 ILE C 244 ASN C 245 0 -3.77
CISPEP 10 LYS C 410 SER C 411 0 -7.13
CISPEP 11 ASN C 510 ASP C 511 0 -3.52
CISPEP 12 LYS C 678 GLY C 679 0 -19.63
CISPEP 13 ASN E 175 VAL E 176 0 13.22
CISPEP 14 ALA E 242 TYR E 243 0 3.91
CISPEP 15 ILE E 244 ASN E 245 0 -3.71
CISPEP 16 LYS E 410 SER E 411 0 -7.11
CISPEP 17 ASN E 510 ASP E 511 0 -3.52
CISPEP 18 LYS E 678 GLY E 679 0 -19.77
CISPEP 19 GLY B 89 ASN B 90 0 4.67
CISPEP 20 GLY D 89 ASN D 90 0 4.60
CISPEP 21 GLY F 89 ASN F 90 0 4.60
CRYST1 1.000 1.000 1.000 90.00 90.00 90.00 P 1
ORIGX1 1.000000 0.000000 0.000000 0.00000
ORIGX2 0.000000 1.000000 0.000000 0.00000
ORIGX3 0.000000 0.000000 1.000000 0.00000
SCALE1 1.000000 0.000000 0.000000 0.00000
SCALE2 0.000000 1.000000 0.000000 0.00000
SCALE3 0.000000 0.000000 1.000000 0.00000
(ATOM LINES ARE NOT SHOWN.)
END
