HEADER CHAPERONE 04-MAR-20 6W1Z
TITLE CLPAP ENGAGED1 STATE BOUND TO REPA-GFP
COMPND MOL_ID: 1;
COMPND 2 MOLECULE: ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT;
COMPND 3 CHAIN: G, H, I, J, K, L, M, N, O, P, Q, R, S, T;
COMPND 4 SYNONYM: ENDOPEPTIDASE CLP;
COMPND 5 EC: 3.4.21.92;
COMPND 6 ENGINEERED: YES;
COMPND 7 MOL_ID: 2;
COMPND 8 MOLECULE: ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPA;
COMPND 9 CHAIN: A, B, C, D, E, F;
COMPND 10 ENGINEERED: YES;
COMPND 11 MOL_ID: 3;
COMPND 12 MOLECULE: REPA, GREEN FLUORESCENT PROTEIN FUSION;
COMPND 13 CHAIN: X;
COMPND 14 ENGINEERED: YES
SOURCE MOL_ID: 1;
SOURCE 2 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;
SOURCE 3 ORGANISM_TAXID: 562;
SOURCE 4 GENE: CLPP, A1WS_00920;
SOURCE 5 EXPRESSION_SYSTEM: ESCHERICHIA COLI;
SOURCE 6 EXPRESSION_SYSTEM_TAXID: 562;
SOURCE 7 MOL_ID: 2;
SOURCE 8 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI (STRAIN K12);
SOURCE 9 ORGANISM_TAXID: 83333;
SOURCE 10 STRAIN: K12;
SOURCE 11 GENE: CLPA, LOPD, B0882, JW0866;
SOURCE 12 EXPRESSION_SYSTEM: ESCHERICHIA COLI;
SOURCE 13 EXPRESSION_SYSTEM_TAXID: 562;
SOURCE 14 MOL_ID: 3;
SOURCE 15 ORGANISM_SCIENTIFIC: SYNTHETIC CONSTRUCT;
SOURCE 16 ORGANISM_TAXID: 32630;
SOURCE 17 EXPRESSION_SYSTEM: ESCHERICHIA COLI;
SOURCE 18 EXPRESSION_SYSTEM_TAXID: 562
KEYWDS AAA+, CHAPERONE, PROTEASE, HSP100, ATPASE
EXPDTA ELECTRON MICROSCOPY
AUTHOR K.L.LOPEZ,A.N.RIZO,E.TSE,J.LIN,N.W.SCULL,A.C.THWIN,A.L.LUCIUS,
AUTHOR 2 J.SHORTER,D.R.SOUTHWORTH
REVDAT 4 06-MAR-24 6W1Z 1 REMARK
REVDAT 3 27-MAY-20 6W1Z 1 JRNL
REVDAT 2 13-MAY-20 6W1Z 1 JRNL
REVDAT 1 06-MAY-20 6W1Z 0
JRNL AUTH K.E.LOPEZ,A.N.RIZO,E.TSE,J.LIN,N.W.SCULL,A.C.THWIN,
JRNL AUTH 2 A.L.LUCIUS,J.SHORTER,D.R.SOUTHWORTH
JRNL TITL CONFORMATIONAL PLASTICITY OF THE CLPAP AAA+ PROTEASE COUPLES
JRNL TITL 2 PROTEIN UNFOLDING AND PROTEOLYSIS.
JRNL REF NAT.STRUCT.MOL.BIOL. V. 27 406 2020
JRNL REFN ESSN 1545-9985
JRNL PMID 32313240
JRNL DOI 10.1038/S41594-020-0409-5
REMARK 2
REMARK 2 RESOLUTION. 2.70 ANGSTROMS.
REMARK 3
REMARK 3 REFINEMENT.
REMARK 3 SOFTWARE PACKAGES : CRYOSPARC
REMARK 3 RECONSTRUCTION SCHEMA : NULL
REMARK 3
REMARK 3 EM MAP-MODEL FITTING AND REFINEMENT
REMARK 3 PDB ENTRY : NULL
REMARK 3 REFINEMENT SPACE : NULL
REMARK 3 REFINEMENT PROTOCOL : NULL
REMARK 3 REFINEMENT TARGET : NULL
REMARK 3 OVERALL ANISOTROPIC B VALUE : NULL
REMARK 3
REMARK 3 FITTING PROCEDURE : NULL
REMARK 3
REMARK 3 EM IMAGE RECONSTRUCTION STATISTICS
REMARK 3 NOMINAL PIXEL SIZE (ANGSTROMS) : NULL
REMARK 3 ACTUAL PIXEL SIZE (ANGSTROMS) : NULL
REMARK 3 EFFECTIVE RESOLUTION (ANGSTROMS) : 2.700
REMARK 3 NUMBER OF PARTICLES : 176232
REMARK 3 CTF CORRECTION METHOD : PHASE FLIPPING AND AMPLITUDE
REMARK 3 CORRECTION
REMARK 3
REMARK 3 EM RECONSTRUCTION MAGNIFICATION CALIBRATION: NULL
REMARK 3
REMARK 3 OTHER DETAILS: NULL
REMARK 4
REMARK 4 6W1Z COMPLIES WITH FORMAT V. 3.30, 13-JUL-11
REMARK 100
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 05-MAR-20.
REMARK 100 THE DEPOSITION ID IS D_1000246018.
REMARK 245
REMARK 245 EXPERIMENTAL DETAILS
REMARK 245 RECONSTRUCTION METHOD : SINGLE PARTICLE
REMARK 245 SPECIMEN TYPE : NULL
REMARK 245
REMARK 245 ELECTRON MICROSCOPE SAMPLE
REMARK 245 SAMPLE TYPE : PARTICLE
REMARK 245 PARTICLE TYPE : POINT
REMARK 245 NAME OF SAMPLE : CLPAP; ATP-DEPENDENT CLP
REMARK 245 PROTEASE ATP-BINDING SUBUNIT
REMARK 245 CLPA; ATP-DEPENDENT CLP
REMARK 245 PROTEASE PROTEOLYTIC SUBUNIT;
REMARK 245 REPA, GREEN FLUORESCENT PROTEIN
REMARK 245 FUSION
REMARK 245 SAMPLE CONCENTRATION (MG ML-1) : NULL
REMARK 245 SAMPLE SUPPORT DETAILS : NULL
REMARK 245 SAMPLE VITRIFICATION DETAILS : NULL
REMARK 245 SAMPLE BUFFER : NULL
REMARK 245 PH : 7.50
REMARK 245 SAMPLE DETAILS : NULL
REMARK 245
REMARK 245 DATA ACQUISITION
REMARK 245 DATE OF EXPERIMENT : NULL
REMARK 245 NUMBER OF MICROGRAPHS-IMAGES : NULL
REMARK 245 TEMPERATURE (KELVIN) : NULL
REMARK 245 MICROSCOPE MODEL : FEI TITAN KRIOS
REMARK 245 DETECTOR TYPE : GATAN K3 BIOQUANTUM (6K X
REMARK 245 4K)
REMARK 245 MINIMUM DEFOCUS (NM) : 1000.00
REMARK 245 MAXIMUM DEFOCUS (NM) : 2000.00
REMARK 245 MINIMUM TILT ANGLE (DEGREES) : NULL
REMARK 245 MAXIMUM TILT ANGLE (DEGREES) : NULL
REMARK 245 NOMINAL CS : 2.70
REMARK 245 IMAGING MODE : BRIGHT FIELD
REMARK 245 ELECTRON DOSE (ELECTRONS NM**-2) : 6900.00
REMARK 245 ILLUMINATION MODE : FLOOD BEAM
REMARK 245 NOMINAL MAGNIFICATION : 105000
REMARK 245 CALIBRATED MAGNIFICATION : 58616
REMARK 245 SOURCE : FIELD EMISSION GUN
REMARK 245 ACCELERATION VOLTAGE (KV) : 300
REMARK 245 IMAGING DETAILS : NULL
REMARK 247
REMARK 247 ELECTRON MICROSCOPY
REMARK 247 THE COORDINATES IN THIS ENTRY WERE GENERATED FROM ELECTRON
REMARK 247 MICROSCOPY DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE
REMARK 247 THAT CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES
REMARK 247 ON THESE RECORDS ARE MEANINGLESS EXCEPT FOR THE CALCULATION
REMARK 247 OF THE STRUCTURE FACTORS.
REMARK 300
REMARK 300 BIOMOLECULE: 1
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON
REMARK 300 BURIED SURFACE AREA.
REMARK 350
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS
REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.
REMARK 350
REMARK 350 BIOMOLECULE: 1
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: 21-MERIC
REMARK 350 APPLY THE FOLLOWING TO CHAINS: G, H, I, J, K, L, M, N, O, P,
REMARK 350 AND CHAINS: Q, R, S, T, A, B, C, D, E,
REMARK 350 AND CHAINS: F, X
REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000
REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000
REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000
REMARK 465
REMARK 465 MISSING RESIDUES
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)
REMARK 465
REMARK 465 M RES C SSSEQI
REMARK 465 MET G 1
REMARK 465 SER G 2
REMARK 465 TYR G 3
REMARK 465 SER G 4
REMARK 465 GLY G 5
REMARK 465 GLU G 6
REMARK 465 ARG G 7
REMARK 465 ASP G 8
REMARK 465 ASN G 9
REMARK 465 PHE G 10
REMARK 465 ALA G 11
REMARK 465 PRO G 12
REMARK 465 HIS G 13
REMARK 465 MET G 14
REMARK 465 ASN G 207
REMARK 465 MET H 1
REMARK 465 SER H 2
REMARK 465 TYR H 3
REMARK 465 SER H 4
REMARK 465 GLY H 5
REMARK 465 GLU H 6
REMARK 465 ARG H 7
REMARK 465 ASP H 8
REMARK 465 ASN H 9
REMARK 465 PHE H 10
REMARK 465 ALA H 11
REMARK 465 PRO H 12
REMARK 465 HIS H 13
REMARK 465 MET H 14
REMARK 465 ASN H 207
REMARK 465 MET I 1
REMARK 465 SER I 2
REMARK 465 TYR I 3
REMARK 465 SER I 4
REMARK 465 GLY I 5
REMARK 465 GLU I 6
REMARK 465 ARG I 7
REMARK 465 ASP I 8
REMARK 465 ASN I 9
REMARK 465 PHE I 10
REMARK 465 ALA I 11
REMARK 465 PRO I 12
REMARK 465 HIS I 13
REMARK 465 MET I 14
REMARK 465 ASN I 207
REMARK 465 MET J 1
REMARK 465 SER J 2
REMARK 465 TYR J 3
REMARK 465 SER J 4
REMARK 465 GLY J 5
REMARK 465 GLU J 6
REMARK 465 ARG J 7
REMARK 465 ASP J 8
REMARK 465 ASN J 9
REMARK 465 PHE J 10
REMARK 465 ALA J 11
REMARK 465 PRO J 12
REMARK 465 HIS J 13
REMARK 465 MET J 14
REMARK 465 ASN J 207
REMARK 465 MET K 1
REMARK 465 SER K 2
REMARK 465 TYR K 3
REMARK 465 SER K 4
REMARK 465 GLY K 5
REMARK 465 GLU K 6
REMARK 465 ARG K 7
REMARK 465 ASP K 8
REMARK 465 ASN K 9
REMARK 465 PHE K 10
REMARK 465 ALA K 11
REMARK 465 PRO K 12
REMARK 465 HIS K 13
REMARK 465 MET K 14
REMARK 465 ASN K 207
REMARK 465 MET L 1
REMARK 465 SER L 2
REMARK 465 TYR L 3
REMARK 465 SER L 4
REMARK 465 GLY L 5
REMARK 465 GLU L 6
REMARK 465 ARG L 7
REMARK 465 ASP L 8
REMARK 465 ASN L 9
REMARK 465 PHE L 10
REMARK 465 ALA L 11
REMARK 465 PRO L 12
REMARK 465 HIS L 13
REMARK 465 MET L 14
REMARK 465 ASN L 207
REMARK 465 MET M 1
REMARK 465 SER M 2
REMARK 465 TYR M 3
REMARK 465 SER M 4
REMARK 465 GLY M 5
REMARK 465 GLU M 6
REMARK 465 ARG M 7
REMARK 465 ASP M 8
REMARK 465 ASN M 9
REMARK 465 PHE M 10
REMARK 465 ALA M 11
REMARK 465 PRO M 12
REMARK 465 HIS M 13
REMARK 465 MET M 14
REMARK 465 ASN M 207
REMARK 465 MET N 1
REMARK 465 SER N 2
REMARK 465 TYR N 3
REMARK 465 SER N 4
REMARK 465 GLY N 5
REMARK 465 GLU N 6
REMARK 465 ARG N 7
REMARK 465 ASP N 8
REMARK 465 ASN N 9
REMARK 465 PHE N 10
REMARK 465 ALA N 11
REMARK 465 PRO N 12
REMARK 465 HIS N 13
REMARK 465 MET N 14
REMARK 465 ASN N 207
REMARK 465 MET O 1
REMARK 465 SER O 2
REMARK 465 TYR O 3
REMARK 465 SER O 4
REMARK 465 GLY O 5
REMARK 465 GLU O 6
REMARK 465 ARG O 7
REMARK 465 ASP O 8
REMARK 465 ASN O 9
REMARK 465 PHE O 10
REMARK 465 ALA O 11
REMARK 465 PRO O 12
REMARK 465 HIS O 13
REMARK 465 MET O 14
REMARK 465 ASN O 207
REMARK 465 MET P 1
REMARK 465 SER P 2
REMARK 465 TYR P 3
REMARK 465 SER P 4
REMARK 465 GLY P 5
REMARK 465 GLU P 6
REMARK 465 ARG P 7
REMARK 465 ASP P 8
REMARK 465 ASN P 9
REMARK 465 PHE P 10
REMARK 465 ALA P 11
REMARK 465 PRO P 12
REMARK 465 HIS P 13
REMARK 465 MET P 14
REMARK 465 ASN P 207
REMARK 465 MET Q 1
REMARK 465 SER Q 2
REMARK 465 TYR Q 3
REMARK 465 SER Q 4
REMARK 465 GLY Q 5
REMARK 465 GLU Q 6
REMARK 465 ARG Q 7
REMARK 465 ASP Q 8
REMARK 465 ASN Q 9
REMARK 465 PHE Q 10
REMARK 465 ALA Q 11
REMARK 465 PRO Q 12
REMARK 465 HIS Q 13
REMARK 465 MET Q 14
REMARK 465 ASN Q 207
REMARK 465 MET R 1
REMARK 465 SER R 2
REMARK 465 TYR R 3
REMARK 465 SER R 4
REMARK 465 GLY R 5
REMARK 465 GLU R 6
REMARK 465 ARG R 7
REMARK 465 ASP R 8
REMARK 465 ASN R 9
REMARK 465 PHE R 10
REMARK 465 ALA R 11
REMARK 465 PRO R 12
REMARK 465 HIS R 13
REMARK 465 MET R 14
REMARK 465 ASN R 207
REMARK 465 MET S 1
REMARK 465 SER S 2
REMARK 465 TYR S 3
REMARK 465 SER S 4
REMARK 465 GLY S 5
REMARK 465 GLU S 6
REMARK 465 ARG S 7
REMARK 465 ASP S 8
REMARK 465 ASN S 9
REMARK 465 PHE S 10
REMARK 465 ALA S 11
REMARK 465 PRO S 12
REMARK 465 HIS S 13
REMARK 465 MET S 14
REMARK 465 ASN S 207
REMARK 465 MET T 1
REMARK 465 SER T 2
REMARK 465 TYR T 3
REMARK 465 SER T 4
REMARK 465 GLY T 5
REMARK 465 GLU T 6
REMARK 465 ARG T 7
REMARK 465 ASP T 8
REMARK 465 ASN T 9
REMARK 465 PHE T 10
REMARK 465 ALA T 11
REMARK 465 PRO T 12
REMARK 465 HIS T 13
REMARK 465 MET T 14
REMARK 465 ASN T 207
REMARK 465 MET A 1
REMARK 465 LEU A 2
REMARK 465 ASN A 3
REMARK 465 GLN A 4
REMARK 465 GLU A 5
REMARK 465 LEU A 6
REMARK 465 GLU A 7
REMARK 465 LEU A 8
REMARK 465 SER A 9
REMARK 465 LEU A 10
REMARK 465 ASN A 11
REMARK 465 MET A 12
REMARK 465 ALA A 13
REMARK 465 PHE A 14
REMARK 465 ALA A 15
REMARK 465 ARG A 16
REMARK 465 ALA A 17
REMARK 465 ARG A 18
REMARK 465 GLU A 19
REMARK 465 HIS A 20
REMARK 465 ARG A 21
REMARK 465 HIS A 22
REMARK 465 GLU A 23
REMARK 465 PHE A 24
REMARK 465 MET A 25
REMARK 465 THR A 26
REMARK 465 VAL A 27
REMARK 465 GLU A 28
REMARK 465 HIS A 29
REMARK 465 LEU A 30
REMARK 465 LEU A 31
REMARK 465 LEU A 32
REMARK 465 ALA A 33
REMARK 465 LEU A 34
REMARK 465 LEU A 35
REMARK 465 SER A 36
REMARK 465 ASN A 37
REMARK 465 PRO A 38
REMARK 465 SER A 39
REMARK 465 ALA A 40
REMARK 465 ARG A 41
REMARK 465 GLU A 42
REMARK 465 ALA A 43
REMARK 465 LEU A 44
REMARK 465 GLU A 45
REMARK 465 ALA A 46
REMARK 465 CYS A 47
REMARK 465 SER A 48
REMARK 465 VAL A 49
REMARK 465 ASP A 50
REMARK 465 LEU A 51
REMARK 465 VAL A 52
REMARK 465 ALA A 53
REMARK 465 LEU A 54
REMARK 465 ARG A 55
REMARK 465 GLN A 56
REMARK 465 GLU A 57
REMARK 465 LEU A 58
REMARK 465 GLU A 59
REMARK 465 ALA A 60
REMARK 465 PHE A 61
REMARK 465 ILE A 62
REMARK 465 GLU A 63
REMARK 465 GLN A 64
REMARK 465 THR A 65
REMARK 465 THR A 66
REMARK 465 PRO A 67
REMARK 465 VAL A 68
REMARK 465 LEU A 69
REMARK 465 PRO A 70
REMARK 465 ALA A 71
REMARK 465 SER A 72
REMARK 465 GLU A 73
REMARK 465 GLU A 74
REMARK 465 GLU A 75
REMARK 465 ARG A 76
REMARK 465 ASP A 77
REMARK 465 THR A 78
REMARK 465 GLN A 79
REMARK 465 PRO A 80
REMARK 465 THR A 81
REMARK 465 LEU A 82
REMARK 465 SER A 83
REMARK 465 PHE A 84
REMARK 465 GLN A 85
REMARK 465 ARG A 86
REMARK 465 VAL A 87
REMARK 465 LEU A 88
REMARK 465 GLN A 89
REMARK 465 ARG A 90
REMARK 465 ALA A 91
REMARK 465 VAL A 92
REMARK 465 PHE A 93
REMARK 465 HIS A 94
REMARK 465 VAL A 95
REMARK 465 GLN A 96
REMARK 465 SER A 97
REMARK 465 SER A 98
REMARK 465 GLY A 99
REMARK 465 ARG A 100
REMARK 465 ASN A 101
REMARK 465 GLU A 102
REMARK 465 VAL A 103
REMARK 465 THR A 104
REMARK 465 GLY A 105
REMARK 465 ALA A 106
REMARK 465 ASN A 107
REMARK 465 VAL A 108
REMARK 465 LEU A 109
REMARK 465 VAL A 110
REMARK 465 ALA A 111
REMARK 465 ILE A 112
REMARK 465 PHE A 113
REMARK 465 SER A 114
REMARK 465 GLU A 115
REMARK 465 GLN A 116
REMARK 465 GLU A 117
REMARK 465 SER A 118
REMARK 465 GLN A 119
REMARK 465 ALA A 120
REMARK 465 ALA A 121
REMARK 465 TYR A 122
REMARK 465 LEU A 123
REMARK 465 LEU A 124
REMARK 465 ARG A 125
REMARK 465 LYS A 126
REMARK 465 HIS A 127
REMARK 465 GLU A 128
REMARK 465 VAL A 129
REMARK 465 SER A 130
REMARK 465 ARG A 131
REMARK 465 LEU A 132
REMARK 465 ASP A 133
REMARK 465 VAL A 134
REMARK 465 VAL A 135
REMARK 465 ASN A 136
REMARK 465 PHE A 137
REMARK 465 ILE A 138
REMARK 465 SER A 139
REMARK 465 HIS A 140
REMARK 465 GLY A 141
REMARK 465 THR A 142
REMARK 465 ARG A 143
REMARK 465 LYS A 144
REMARK 465 ASP A 145
REMARK 465 GLU A 146
REMARK 465 PRO A 147
REMARK 465 THR A 148
REMARK 465 GLN A 149
REMARK 465 SER A 150
REMARK 465 SER A 151
REMARK 465 ASP A 152
REMARK 465 PRO A 153
REMARK 465 GLY A 154
REMARK 465 SER A 155
REMARK 465 GLN A 156
REMARK 465 PRO A 157
REMARK 465 ASN A 158
REMARK 465 SER A 159
REMARK 465 GLU A 160
REMARK 465 GLU A 161
REMARK 465 GLN A 162
REMARK 465 ALA A 163
REMARK 465 GLY A 164
REMARK 465 GLY A 165
REMARK 465 GLU A 166
REMARK 465 GLU A 167
REMARK 465 ARG A 168
REMARK 465 GLN A 747
REMARK 465 SER A 748
REMARK 465 ALA A 749
REMARK 465 GLN A 750
REMARK 465 LYS A 751
REMARK 465 HIS A 752
REMARK 465 LYS A 753
REMARK 465 ALA A 754
REMARK 465 GLU A 755
REMARK 465 ALA A 756
REMARK 465 ALA A 757
REMARK 465 HIS A 758
REMARK 465 MET B 1
REMARK 465 LEU B 2
REMARK 465 ASN B 3
REMARK 465 GLN B 4
REMARK 465 GLU B 5
REMARK 465 LEU B 6
REMARK 465 GLU B 7
REMARK 465 LEU B 8
REMARK 465 SER B 9
REMARK 465 LEU B 10
REMARK 465 ASN B 11
REMARK 465 MET B 12
REMARK 465 ALA B 13
REMARK 465 PHE B 14
REMARK 465 ALA B 15
REMARK 465 ARG B 16
REMARK 465 ALA B 17
REMARK 465 ARG B 18
REMARK 465 GLU B 19
REMARK 465 HIS B 20
REMARK 465 ARG B 21
REMARK 465 HIS B 22
REMARK 465 GLU B 23
REMARK 465 PHE B 24
REMARK 465 MET B 25
REMARK 465 THR B 26
REMARK 465 VAL B 27
REMARK 465 GLU B 28
REMARK 465 HIS B 29
REMARK 465 LEU B 30
REMARK 465 LEU B 31
REMARK 465 LEU B 32
REMARK 465 ALA B 33
REMARK 465 LEU B 34
REMARK 465 LEU B 35
REMARK 465 SER B 36
REMARK 465 ASN B 37
REMARK 465 PRO B 38
REMARK 465 SER B 39
REMARK 465 ALA B 40
REMARK 465 ARG B 41
REMARK 465 GLU B 42
REMARK 465 ALA B 43
REMARK 465 LEU B 44
REMARK 465 GLU B 45
REMARK 465 ALA B 46
REMARK 465 CYS B 47
REMARK 465 SER B 48
REMARK 465 VAL B 49
REMARK 465 ASP B 50
REMARK 465 LEU B 51
REMARK 465 VAL B 52
REMARK 465 ALA B 53
REMARK 465 LEU B 54
REMARK 465 ARG B 55
REMARK 465 GLN B 56
REMARK 465 GLU B 57
REMARK 465 LEU B 58
REMARK 465 GLU B 59
REMARK 465 ALA B 60
REMARK 465 PHE B 61
REMARK 465 ILE B 62
REMARK 465 GLU B 63
REMARK 465 GLN B 64
REMARK 465 THR B 65
REMARK 465 THR B 66
REMARK 465 PRO B 67
REMARK 465 VAL B 68
REMARK 465 LEU B 69
REMARK 465 PRO B 70
REMARK 465 ALA B 71
REMARK 465 SER B 72
REMARK 465 GLU B 73
REMARK 465 GLU B 74
REMARK 465 GLU B 75
REMARK 465 ARG B 76
REMARK 465 ASP B 77
REMARK 465 THR B 78
REMARK 465 GLN B 79
REMARK 465 PRO B 80
REMARK 465 THR B 81
REMARK 465 LEU B 82
REMARK 465 SER B 83
REMARK 465 PHE B 84
REMARK 465 GLN B 85
REMARK 465 ARG B 86
REMARK 465 VAL B 87
REMARK 465 LEU B 88
REMARK 465 GLN B 89
REMARK 465 ARG B 90
REMARK 465 ALA B 91
REMARK 465 VAL B 92
REMARK 465 PHE B 93
REMARK 465 HIS B 94
REMARK 465 VAL B 95
REMARK 465 GLN B 96
REMARK 465 SER B 97
REMARK 465 SER B 98
REMARK 465 GLY B 99
REMARK 465 ARG B 100
REMARK 465 ASN B 101
REMARK 465 GLU B 102
REMARK 465 VAL B 103
REMARK 465 THR B 104
REMARK 465 GLY B 105
REMARK 465 ALA B 106
REMARK 465 ASN B 107
REMARK 465 VAL B 108
REMARK 465 LEU B 109
REMARK 465 VAL B 110
REMARK 465 ALA B 111
REMARK 465 ILE B 112
REMARK 465 PHE B 113
REMARK 465 SER B 114
REMARK 465 GLU B 115
REMARK 465 GLN B 116
REMARK 465 GLU B 117
REMARK 465 SER B 118
REMARK 465 GLN B 119
REMARK 465 ALA B 120
REMARK 465 ALA B 121
REMARK 465 TYR B 122
REMARK 465 LEU B 123
REMARK 465 LEU B 124
REMARK 465 ARG B 125
REMARK 465 LYS B 126
REMARK 465 HIS B 127
REMARK 465 GLU B 128
REMARK 465 VAL B 129
REMARK 465 SER B 130
REMARK 465 ARG B 131
REMARK 465 LEU B 132
REMARK 465 ASP B 133
REMARK 465 VAL B 134
REMARK 465 VAL B 135
REMARK 465 ASN B 136
REMARK 465 PHE B 137
REMARK 465 ILE B 138
REMARK 465 SER B 139
REMARK 465 HIS B 140
REMARK 465 GLY B 141
REMARK 465 THR B 142
REMARK 465 ARG B 143
REMARK 465 LYS B 144
REMARK 465 ASP B 145
REMARK 465 GLU B 146
REMARK 465 PRO B 147
REMARK 465 THR B 148
REMARK 465 GLN B 149
REMARK 465 SER B 150
REMARK 465 SER B 151
REMARK 465 ASP B 152
REMARK 465 PRO B 153
REMARK 465 GLY B 154
REMARK 465 SER B 155
REMARK 465 GLN B 156
REMARK 465 PRO B 157
REMARK 465 ASN B 158
REMARK 465 SER B 159
REMARK 465 GLU B 160
REMARK 465 GLU B 161
REMARK 465 GLN B 162
REMARK 465 ALA B 163
REMARK 465 GLY B 164
REMARK 465 GLY B 165
REMARK 465 GLU B 166
REMARK 465 GLU B 167
REMARK 465 ARG B 168
REMARK 465 GLN B 747
REMARK 465 SER B 748
REMARK 465 ALA B 749
REMARK 465 GLN B 750
REMARK 465 LYS B 751
REMARK 465 HIS B 752
REMARK 465 LYS B 753
REMARK 465 ALA B 754
REMARK 465 GLU B 755
REMARK 465 ALA B 756
REMARK 465 ALA B 757
REMARK 465 HIS B 758
REMARK 465 MET C 1
REMARK 465 LEU C 2
REMARK 465 ASN C 3
REMARK 465 GLN C 4
REMARK 465 GLU C 5
REMARK 465 LEU C 6
REMARK 465 GLU C 7
REMARK 465 LEU C 8
REMARK 465 SER C 9
REMARK 465 LEU C 10
REMARK 465 ASN C 11
REMARK 465 MET C 12
REMARK 465 ALA C 13
REMARK 465 PHE C 14
REMARK 465 ALA C 15
REMARK 465 ARG C 16
REMARK 465 ALA C 17
REMARK 465 ARG C 18
REMARK 465 GLU C 19
REMARK 465 HIS C 20
REMARK 465 ARG C 21
REMARK 465 HIS C 22
REMARK 465 GLU C 23
REMARK 465 PHE C 24
REMARK 465 MET C 25
REMARK 465 THR C 26
REMARK 465 VAL C 27
REMARK 465 GLU C 28
REMARK 465 HIS C 29
REMARK 465 LEU C 30
REMARK 465 LEU C 31
REMARK 465 LEU C 32
REMARK 465 ALA C 33
REMARK 465 LEU C 34
REMARK 465 LEU C 35
REMARK 465 SER C 36
REMARK 465 ASN C 37
REMARK 465 PRO C 38
REMARK 465 SER C 39
REMARK 465 ALA C 40
REMARK 465 ARG C 41
REMARK 465 GLU C 42
REMARK 465 ALA C 43
REMARK 465 LEU C 44
REMARK 465 GLU C 45
REMARK 465 ALA C 46
REMARK 465 CYS C 47
REMARK 465 SER C 48
REMARK 465 VAL C 49
REMARK 465 ASP C 50
REMARK 465 LEU C 51
REMARK 465 VAL C 52
REMARK 465 ALA C 53
REMARK 465 LEU C 54
REMARK 465 ARG C 55
REMARK 465 GLN C 56
REMARK 465 GLU C 57
REMARK 465 LEU C 58
REMARK 465 GLU C 59
REMARK 465 ALA C 60
REMARK 465 PHE C 61
REMARK 465 ILE C 62
REMARK 465 GLU C 63
REMARK 465 GLN C 64
REMARK 465 THR C 65
REMARK 465 THR C 66
REMARK 465 PRO C 67
REMARK 465 VAL C 68
REMARK 465 LEU C 69
REMARK 465 PRO C 70
REMARK 465 ALA C 71
REMARK 465 SER C 72
REMARK 465 GLU C 73
REMARK 465 GLU C 74
REMARK 465 GLU C 75
REMARK 465 ARG C 76
REMARK 465 ASP C 77
REMARK 465 THR C 78
REMARK 465 GLN C 79
REMARK 465 PRO C 80
REMARK 465 THR C 81
REMARK 465 LEU C 82
REMARK 465 SER C 83
REMARK 465 PHE C 84
REMARK 465 GLN C 85
REMARK 465 ARG C 86
REMARK 465 VAL C 87
REMARK 465 LEU C 88
REMARK 465 GLN C 89
REMARK 465 ARG C 90
REMARK 465 ALA C 91
REMARK 465 VAL C 92
REMARK 465 PHE C 93
REMARK 465 HIS C 94
REMARK 465 VAL C 95
REMARK 465 GLN C 96
REMARK 465 SER C 97
REMARK 465 SER C 98
REMARK 465 GLY C 99
REMARK 465 ARG C 100
REMARK 465 ASN C 101
REMARK 465 GLU C 102
REMARK 465 VAL C 103
REMARK 465 THR C 104
REMARK 465 GLY C 105
REMARK 465 ALA C 106
REMARK 465 ASN C 107
REMARK 465 VAL C 108
REMARK 465 LEU C 109
REMARK 465 VAL C 110
REMARK 465 ALA C 111
REMARK 465 ILE C 112
REMARK 465 PHE C 113
REMARK 465 SER C 114
REMARK 465 GLU C 115
REMARK 465 GLN C 116
REMARK 465 GLU C 117
REMARK 465 SER C 118
REMARK 465 GLN C 119
REMARK 465 ALA C 120
REMARK 465 ALA C 121
REMARK 465 TYR C 122
REMARK 465 LEU C 123
REMARK 465 LEU C 124
REMARK 465 ARG C 125
REMARK 465 LYS C 126
REMARK 465 HIS C 127
REMARK 465 GLU C 128
REMARK 465 VAL C 129
REMARK 465 SER C 130
REMARK 465 ARG C 131
REMARK 465 LEU C 132
REMARK 465 ASP C 133
REMARK 465 VAL C 134
REMARK 465 VAL C 135
REMARK 465 ASN C 136
REMARK 465 PHE C 137
REMARK 465 ILE C 138
REMARK 465 SER C 139
REMARK 465 HIS C 140
REMARK 465 GLY C 141
REMARK 465 THR C 142
REMARK 465 ARG C 143
REMARK 465 LYS C 144
REMARK 465 ASP C 145
REMARK 465 GLU C 146
REMARK 465 PRO C 147
REMARK 465 THR C 148
REMARK 465 GLN C 149
REMARK 465 SER C 150
REMARK 465 SER C 151
REMARK 465 ASP C 152
REMARK 465 PRO C 153
REMARK 465 GLY C 154
REMARK 465 SER C 155
REMARK 465 GLN C 156
REMARK 465 PRO C 157
REMARK 465 ASN C 158
REMARK 465 SER C 159
REMARK 465 GLU C 160
REMARK 465 GLU C 161
REMARK 465 GLN C 162
REMARK 465 ALA C 163
REMARK 465 GLY C 164
REMARK 465 GLY C 165
REMARK 465 GLU C 166
REMARK 465 GLU C 167
REMARK 465 ARG C 168
REMARK 465 GLN C 747
REMARK 465 SER C 748
REMARK 465 ALA C 749
REMARK 465 GLN C 750
REMARK 465 LYS C 751
REMARK 465 HIS C 752
REMARK 465 LYS C 753
REMARK 465 ALA C 754
REMARK 465 GLU C 755
REMARK 465 ALA C 756
REMARK 465 ALA C 757
REMARK 465 HIS C 758
REMARK 465 MET D 1
REMARK 465 LEU D 2
REMARK 465 ASN D 3
REMARK 465 GLN D 4
REMARK 465 GLU D 5
REMARK 465 LEU D 6
REMARK 465 GLU D 7
REMARK 465 LEU D 8
REMARK 465 SER D 9
REMARK 465 LEU D 10
REMARK 465 ASN D 11
REMARK 465 MET D 12
REMARK 465 ALA D 13
REMARK 465 PHE D 14
REMARK 465 ALA D 15
REMARK 465 ARG D 16
REMARK 465 ALA D 17
REMARK 465 ARG D 18
REMARK 465 GLU D 19
REMARK 465 HIS D 20
REMARK 465 ARG D 21
REMARK 465 HIS D 22
REMARK 465 GLU D 23
REMARK 465 PHE D 24
REMARK 465 MET D 25
REMARK 465 THR D 26
REMARK 465 VAL D 27
REMARK 465 GLU D 28
REMARK 465 HIS D 29
REMARK 465 LEU D 30
REMARK 465 LEU D 31
REMARK 465 LEU D 32
REMARK 465 ALA D 33
REMARK 465 LEU D 34
REMARK 465 LEU D 35
REMARK 465 SER D 36
REMARK 465 ASN D 37
REMARK 465 PRO D 38
REMARK 465 SER D 39
REMARK 465 ALA D 40
REMARK 465 ARG D 41
REMARK 465 GLU D 42
REMARK 465 ALA D 43
REMARK 465 LEU D 44
REMARK 465 GLU D 45
REMARK 465 ALA D 46
REMARK 465 CYS D 47
REMARK 465 SER D 48
REMARK 465 VAL D 49
REMARK 465 ASP D 50
REMARK 465 LEU D 51
REMARK 465 VAL D 52
REMARK 465 ALA D 53
REMARK 465 LEU D 54
REMARK 465 ARG D 55
REMARK 465 GLN D 56
REMARK 465 GLU D 57
REMARK 465 LEU D 58
REMARK 465 GLU D 59
REMARK 465 ALA D 60
REMARK 465 PHE D 61
REMARK 465 ILE D 62
REMARK 465 GLU D 63
REMARK 465 GLN D 64
REMARK 465 THR D 65
REMARK 465 THR D 66
REMARK 465 PRO D 67
REMARK 465 VAL D 68
REMARK 465 LEU D 69
REMARK 465 PRO D 70
REMARK 465 ALA D 71
REMARK 465 SER D 72
REMARK 465 GLU D 73
REMARK 465 GLU D 74
REMARK 465 GLU D 75
REMARK 465 ARG D 76
REMARK 465 ASP D 77
REMARK 465 THR D 78
REMARK 465 GLN D 79
REMARK 465 PRO D 80
REMARK 465 THR D 81
REMARK 465 LEU D 82
REMARK 465 SER D 83
REMARK 465 PHE D 84
REMARK 465 GLN D 85
REMARK 465 ARG D 86
REMARK 465 VAL D 87
REMARK 465 LEU D 88
REMARK 465 GLN D 89
REMARK 465 ARG D 90
REMARK 465 ALA D 91
REMARK 465 VAL D 92
REMARK 465 PHE D 93
REMARK 465 HIS D 94
REMARK 465 VAL D 95
REMARK 465 GLN D 96
REMARK 465 SER D 97
REMARK 465 SER D 98
REMARK 465 GLY D 99
REMARK 465 ARG D 100
REMARK 465 ASN D 101
REMARK 465 GLU D 102
REMARK 465 VAL D 103
REMARK 465 THR D 104
REMARK 465 GLY D 105
REMARK 465 ALA D 106
REMARK 465 ASN D 107
REMARK 465 VAL D 108
REMARK 465 LEU D 109
REMARK 465 VAL D 110
REMARK 465 ALA D 111
REMARK 465 ILE D 112
REMARK 465 PHE D 113
REMARK 465 SER D 114
REMARK 465 GLU D 115
REMARK 465 GLN D 116
REMARK 465 GLU D 117
REMARK 465 SER D 118
REMARK 465 GLN D 119
REMARK 465 ALA D 120
REMARK 465 ALA D 121
REMARK 465 TYR D 122
REMARK 465 LEU D 123
REMARK 465 LEU D 124
REMARK 465 ARG D 125
REMARK 465 LYS D 126
REMARK 465 HIS D 127
REMARK 465 GLU D 128
REMARK 465 VAL D 129
REMARK 465 SER D 130
REMARK 465 ARG D 131
REMARK 465 LEU D 132
REMARK 465 ASP D 133
REMARK 465 VAL D 134
REMARK 465 VAL D 135
REMARK 465 ASN D 136
REMARK 465 PHE D 137
REMARK 465 ILE D 138
REMARK 465 SER D 139
REMARK 465 HIS D 140
REMARK 465 GLY D 141
REMARK 465 THR D 142
REMARK 465 ARG D 143
REMARK 465 LYS D 144
REMARK 465 ASP D 145
REMARK 465 GLU D 146
REMARK 465 PRO D 147
REMARK 465 THR D 148
REMARK 465 GLN D 149
REMARK 465 SER D 150
REMARK 465 SER D 151
REMARK 465 ASP D 152
REMARK 465 PRO D 153
REMARK 465 GLY D 154
REMARK 465 SER D 155
REMARK 465 GLN D 156
REMARK 465 PRO D 157
REMARK 465 ASN D 158
REMARK 465 SER D 159
REMARK 465 GLU D 160
REMARK 465 GLU D 161
REMARK 465 GLN D 162
REMARK 465 ALA D 163
REMARK 465 GLY D 164
REMARK 465 GLY D 165
REMARK 465 GLU D 166
REMARK 465 GLU D 167
REMARK 465 ARG D 168
REMARK 465 GLN D 747
REMARK 465 SER D 748
REMARK 465 ALA D 749
REMARK 465 GLN D 750
REMARK 465 LYS D 751
REMARK 465 HIS D 752
REMARK 465 LYS D 753
REMARK 465 ALA D 754
REMARK 465 GLU D 755
REMARK 465 ALA D 756
REMARK 465 ALA D 757
REMARK 465 HIS D 758
REMARK 465 MET E 1
REMARK 465 LEU E 2
REMARK 465 ASN E 3
REMARK 465 GLN E 4
REMARK 465 GLU E 5
REMARK 465 LEU E 6
REMARK 465 GLU E 7
REMARK 465 LEU E 8
REMARK 465 SER E 9
REMARK 465 LEU E 10
REMARK 465 ASN E 11
REMARK 465 MET E 12
REMARK 465 ALA E 13
REMARK 465 PHE E 14
REMARK 465 ALA E 15
REMARK 465 ARG E 16
REMARK 465 ALA E 17
REMARK 465 ARG E 18
REMARK 465 GLU E 19
REMARK 465 HIS E 20
REMARK 465 ARG E 21
REMARK 465 HIS E 22
REMARK 465 GLU E 23
REMARK 465 PHE E 24
REMARK 465 MET E 25
REMARK 465 THR E 26
REMARK 465 VAL E 27
REMARK 465 GLU E 28
REMARK 465 HIS E 29
REMARK 465 LEU E 30
REMARK 465 LEU E 31
REMARK 465 LEU E 32
REMARK 465 ALA E 33
REMARK 465 LEU E 34
REMARK 465 LEU E 35
REMARK 465 SER E 36
REMARK 465 ASN E 37
REMARK 465 PRO E 38
REMARK 465 SER E 39
REMARK 465 ALA E 40
REMARK 465 ARG E 41
REMARK 465 GLU E 42
REMARK 465 ALA E 43
REMARK 465 LEU E 44
REMARK 465 GLU E 45
REMARK 465 ALA E 46
REMARK 465 CYS E 47
REMARK 465 SER E 48
REMARK 465 VAL E 49
REMARK 465 ASP E 50
REMARK 465 LEU E 51
REMARK 465 VAL E 52
REMARK 465 ALA E 53
REMARK 465 LEU E 54
REMARK 465 ARG E 55
REMARK 465 GLN E 56
REMARK 465 GLU E 57
REMARK 465 LEU E 58
REMARK 465 GLU E 59
REMARK 465 ALA E 60
REMARK 465 PHE E 61
REMARK 465 ILE E 62
REMARK 465 GLU E 63
REMARK 465 GLN E 64
REMARK 465 THR E 65
REMARK 465 THR E 66
REMARK 465 PRO E 67
REMARK 465 VAL E 68
REMARK 465 LEU E 69
REMARK 465 PRO E 70
REMARK 465 ALA E 71
REMARK 465 SER E 72
REMARK 465 GLU E 73
REMARK 465 GLU E 74
REMARK 465 GLU E 75
REMARK 465 ARG E 76
REMARK 465 ASP E 77
REMARK 465 THR E 78
REMARK 465 GLN E 79
REMARK 465 PRO E 80
REMARK 465 THR E 81
REMARK 465 LEU E 82
REMARK 465 SER E 83
REMARK 465 PHE E 84
REMARK 465 GLN E 85
REMARK 465 ARG E 86
REMARK 465 VAL E 87
REMARK 465 LEU E 88
REMARK 465 GLN E 89
REMARK 465 ARG E 90
REMARK 465 ALA E 91
REMARK 465 VAL E 92
REMARK 465 PHE E 93
REMARK 465 HIS E 94
REMARK 465 VAL E 95
REMARK 465 GLN E 96
REMARK 465 SER E 97
REMARK 465 SER E 98
REMARK 465 GLY E 99
REMARK 465 ARG E 100
REMARK 465 ASN E 101
REMARK 465 GLU E 102
REMARK 465 VAL E 103
REMARK 465 THR E 104
REMARK 465 GLY E 105
REMARK 465 ALA E 106
REMARK 465 ASN E 107
REMARK 465 VAL E 108
REMARK 465 LEU E 109
REMARK 465 VAL E 110
REMARK 465 ALA E 111
REMARK 465 ILE E 112
REMARK 465 PHE E 113
REMARK 465 SER E 114
REMARK 465 GLU E 115
REMARK 465 GLN E 116
REMARK 465 GLU E 117
REMARK 465 SER E 118
REMARK 465 GLN E 119
REMARK 465 ALA E 120
REMARK 465 ALA E 121
REMARK 465 TYR E 122
REMARK 465 LEU E 123
REMARK 465 LEU E 124
REMARK 465 ARG E 125
REMARK 465 LYS E 126
REMARK 465 HIS E 127
REMARK 465 GLU E 128
REMARK 465 VAL E 129
REMARK 465 SER E 130
REMARK 465 ARG E 131
REMARK 465 LEU E 132
REMARK 465 ASP E 133
REMARK 465 VAL E 134
REMARK 465 VAL E 135
REMARK 465 ASN E 136
REMARK 465 PHE E 137
REMARK 465 ILE E 138
REMARK 465 SER E 139
REMARK 465 HIS E 140
REMARK 465 GLY E 141
REMARK 465 THR E 142
REMARK 465 ARG E 143
REMARK 465 LYS E 144
REMARK 465 ASP E 145
REMARK 465 GLU E 146
REMARK 465 PRO E 147
REMARK 465 THR E 148
REMARK 465 GLN E 149
REMARK 465 SER E 150
REMARK 465 SER E 151
REMARK 465 ASP E 152
REMARK 465 PRO E 153
REMARK 465 GLY E 154
REMARK 465 SER E 155
REMARK 465 GLN E 156
REMARK 465 PRO E 157
REMARK 465 ASN E 158
REMARK 465 SER E 159
REMARK 465 GLU E 160
REMARK 465 GLU E 161
REMARK 465 GLN E 162
REMARK 465 ALA E 163
REMARK 465 GLY E 164
REMARK 465 GLY E 165
REMARK 465 GLU E 166
REMARK 465 GLU E 167
REMARK 465 ARG E 168
REMARK 465 GLN E 747
REMARK 465 SER E 748
REMARK 465 ALA E 749
REMARK 465 GLN E 750
REMARK 465 LYS E 751
REMARK 465 HIS E 752
REMARK 465 LYS E 753
REMARK 465 ALA E 754
REMARK 465 GLU E 755
REMARK 465 ALA E 756
REMARK 465 ALA E 757
REMARK 465 HIS E 758
REMARK 465 MET F 1
REMARK 465 LEU F 2
REMARK 465 ASN F 3
REMARK 465 GLN F 4
REMARK 465 GLU F 5
REMARK 465 LEU F 6
REMARK 465 GLU F 7
REMARK 465 LEU F 8
REMARK 465 SER F 9
REMARK 465 LEU F 10
REMARK 465 ASN F 11
REMARK 465 MET F 12
REMARK 465 ALA F 13
REMARK 465 PHE F 14
REMARK 465 ALA F 15
REMARK 465 ARG F 16
REMARK 465 ALA F 17
REMARK 465 ARG F 18
REMARK 465 GLU F 19
REMARK 465 HIS F 20
REMARK 465 ARG F 21
REMARK 465 HIS F 22
REMARK 465 GLU F 23
REMARK 465 PHE F 24
REMARK 465 MET F 25
REMARK 465 THR F 26
REMARK 465 VAL F 27
REMARK 465 GLU F 28
REMARK 465 HIS F 29
REMARK 465 LEU F 30
REMARK 465 LEU F 31
REMARK 465 LEU F 32
REMARK 465 ALA F 33
REMARK 465 LEU F 34
REMARK 465 LEU F 35
REMARK 465 SER F 36
REMARK 465 ASN F 37
REMARK 465 PRO F 38
REMARK 465 SER F 39
REMARK 465 ALA F 40
REMARK 465 ARG F 41
REMARK 465 GLU F 42
REMARK 465 ALA F 43
REMARK 465 LEU F 44
REMARK 465 GLU F 45
REMARK 465 ALA F 46
REMARK 465 CYS F 47
REMARK 465 SER F 48
REMARK 465 VAL F 49
REMARK 465 ASP F 50
REMARK 465 LEU F 51
REMARK 465 VAL F 52
REMARK 465 ALA F 53
REMARK 465 LEU F 54
REMARK 465 ARG F 55
REMARK 465 GLN F 56
REMARK 465 GLU F 57
REMARK 465 LEU F 58
REMARK 465 GLU F 59
REMARK 465 ALA F 60
REMARK 465 PHE F 61
REMARK 465 ILE F 62
REMARK 465 GLU F 63
REMARK 465 GLN F 64
REMARK 465 THR F 65
REMARK 465 THR F 66
REMARK 465 PRO F 67
REMARK 465 VAL F 68
REMARK 465 LEU F 69
REMARK 465 PRO F 70
REMARK 465 ALA F 71
REMARK 465 SER F 72
REMARK 465 GLU F 73
REMARK 465 GLU F 74
REMARK 465 GLU F 75
REMARK 465 ARG F 76
REMARK 465 ASP F 77
REMARK 465 THR F 78
REMARK 465 GLN F 79
REMARK 465 PRO F 80
REMARK 465 THR F 81
REMARK 465 LEU F 82
REMARK 465 SER F 83
REMARK 465 PHE F 84
REMARK 465 GLN F 85
REMARK 465 ARG F 86
REMARK 465 VAL F 87
REMARK 465 LEU F 88
REMARK 465 GLN F 89
REMARK 465 ARG F 90
REMARK 465 ALA F 91
REMARK 465 VAL F 92
REMARK 465 PHE F 93
REMARK 465 HIS F 94
REMARK 465 VAL F 95
REMARK 465 GLN F 96
REMARK 465 SER F 97
REMARK 465 SER F 98
REMARK 465 GLY F 99
REMARK 465 ARG F 100
REMARK 465 ASN F 101
REMARK 465 GLU F 102
REMARK 465 VAL F 103
REMARK 465 THR F 104
REMARK 465 GLY F 105
REMARK 465 ALA F 106
REMARK 465 ASN F 107
REMARK 465 VAL F 108
REMARK 465 LEU F 109
REMARK 465 VAL F 110
REMARK 465 ALA F 111
REMARK 465 ILE F 112
REMARK 465 PHE F 113
REMARK 465 SER F 114
REMARK 465 GLU F 115
REMARK 465 GLN F 116
REMARK 465 GLU F 117
REMARK 465 SER F 118
REMARK 465 GLN F 119
REMARK 465 ALA F 120
REMARK 465 ALA F 121
REMARK 465 TYR F 122
REMARK 465 LEU F 123
REMARK 465 LEU F 124
REMARK 465 ARG F 125
REMARK 465 LYS F 126
REMARK 465 HIS F 127
REMARK 465 GLU F 128
REMARK 465 VAL F 129
REMARK 465 SER F 130
REMARK 465 ARG F 131
REMARK 465 LEU F 132
REMARK 465 ASP F 133
REMARK 465 VAL F 134
REMARK 465 VAL F 135
REMARK 465 ASN F 136
REMARK 465 PHE F 137
REMARK 465 ILE F 138
REMARK 465 SER F 139
REMARK 465 HIS F 140
REMARK 465 GLY F 141
REMARK 465 THR F 142
REMARK 465 ARG F 143
REMARK 465 LYS F 144
REMARK 465 ASP F 145
REMARK 465 GLU F 146
REMARK 465 PRO F 147
REMARK 465 THR F 148
REMARK 465 GLN F 149
REMARK 465 SER F 150
REMARK 465 SER F 151
REMARK 465 ASP F 152
REMARK 465 PRO F 153
REMARK 465 GLY F 154
REMARK 465 SER F 155
REMARK 465 GLN F 156
REMARK 465 PRO F 157
REMARK 465 ASN F 158
REMARK 465 SER F 159
REMARK 465 GLU F 160
REMARK 465 GLU F 161
REMARK 465 GLN F 162
REMARK 465 ALA F 163
REMARK 465 GLY F 164
REMARK 465 GLY F 165
REMARK 465 GLU F 166
REMARK 465 GLU F 167
REMARK 465 ARG F 168
REMARK 465 GLN F 747
REMARK 465 SER F 748
REMARK 465 ALA F 749
REMARK 465 GLN F 750
REMARK 465 LYS F 751
REMARK 465 HIS F 752
REMARK 465 LYS F 753
REMARK 465 ALA F 754
REMARK 465 GLU F 755
REMARK 465 ALA F 756
REMARK 465 ALA F 757
REMARK 465 HIS F 758
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: TORSION ANGLES
REMARK 500
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)
REMARK 500
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400
REMARK 500
REMARK 500 M RES CSSEQI PSI PHI
REMARK 500 THR G 24 -87.61 -118.41
REMARK 500 SER G 25 -79.43 -131.03
REMARK 500 SER G 111 -119.22 58.65
REMARK 500 THR G 204 -72.67 -125.86
REMARK 500 THR H 24 -86.29 -118.54
REMARK 500 SER H 25 -85.92 -102.04
REMARK 500 ARG H 29 80.04 44.39
REMARK 500 ASN H 68 94.60 -164.84
REMARK 500 SER H 111 -121.09 58.95
REMARK 500 THR H 204 -72.86 -126.18
REMARK 500 THR I 24 -96.51 -133.12
REMARK 500 ASN I 68 94.03 -164.84
REMARK 500 SER I 111 -119.96 59.04
REMARK 500 THR I 204 -71.32 -120.38
REMARK 500 THR J 24 -93.17 -131.11
REMARK 500 SER J 25 -73.61 -119.99
REMARK 500 ALA J 54 46.85 -86.62
REMARK 500 ASN J 55 -14.38 -145.59
REMARK 500 ASN J 68 94.16 -165.82
REMARK 500 SER J 111 -122.23 59.54
REMARK 500 HIS J 136 146.81 -171.93
REMARK 500 TYR J 142 134.45 -173.25
REMARK 500 THR J 204 -77.45 -115.03
REMARK 500 THR K 24 -95.80 -131.87
REMARK 500 SER K 25 -71.34 -118.87
REMARK 500 ASP K 72 150.60 -46.29
REMARK 500 SER K 111 -119.07 59.22
REMARK 500 TYR K 142 132.73 -172.61
REMARK 500 THR K 204 -75.84 -121.72
REMARK 500 THR L 24 -84.53 -127.99
REMARK 500 SER L 25 -77.27 -141.57
REMARK 500 ARG L 29 -160.04 47.47
REMARK 500 ASP L 32 43.31 -91.80
REMARK 500 ILE L 33 -58.67 69.10
REMARK 500 ASN L 68 94.68 -160.96
REMARK 500 SER L 111 -119.13 58.72
REMARK 500 THR L 204 -72.25 -125.52
REMARK 500 THR M 24 -90.05 -121.59
REMARK 500 SER M 25 -85.00 -110.57
REMARK 500 ASN M 68 94.57 -165.23
REMARK 500 SER M 111 -122.43 59.12
REMARK 500 THR M 204 -73.63 -119.74
REMARK 500 THR N 24 -88.38 -122.34
REMARK 500 SER N 25 -86.35 -106.04
REMARK 500 GLU N 50 -165.43 -120.33
REMARK 500 ASN N 68 92.15 -163.12
REMARK 500 ILE N 84 -58.86 69.66
REMARK 500 SER N 111 -115.70 59.95
REMARK 500 THR N 204 -77.02 -120.83
REMARK 500 THR O 24 -95.45 -132.39
REMARK 500
REMARK 500 THIS ENTRY HAS 153 RAMACHANDRAN OUTLIERS.
REMARK 500
REMARK 500 REMARK: NULL
REMARK 800
REMARK 800 SITE
REMARK 800 SITE_IDENTIFIER: AC1
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: binding site for residue ATP A 801
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC2
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: binding site for residue ADP A 802
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC3
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: binding site for residue ATP B 801
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC4
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: binding site for residue ATP B 802
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC5
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: binding site for residue ATP C 801
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC6
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: binding site for residue ATP C 802
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC7
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: binding site for residue ATP D 801
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC8
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: binding site for residue ATP D 802
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC9
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: binding site for residue ADP E 801
REMARK 800
REMARK 800 SITE_IDENTIFIER: AD1
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: binding site for residue ATP E 802
REMARK 800
REMARK 800 SITE_IDENTIFIER: AD2
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: binding site for residue ADP F 801
REMARK 800
REMARK 800 SITE_IDENTIFIER: AD3
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: binding site for residue ADP F 802
REMARK 900
REMARK 900 RELATED ENTRIES
REMARK 900 RELATED ID: EMD-21519 RELATED DB: EMDB
REMARK 900 CLPAP ENGAGED1 STATE BOUND TO REPA-GFP
DBREF 6W1Z G 1 207 UNP S1IIE7 S1IIE7_ECOLX 1 207
DBREF 6W1Z H 1 207 UNP S1IIE7 S1IIE7_ECOLX 1 207
DBREF 6W1Z I 1 207 UNP S1IIE7 S1IIE7_ECOLX 1 207
DBREF 6W1Z J 1 207 UNP S1IIE7 S1IIE7_ECOLX 1 207
DBREF 6W1Z K 1 207 UNP S1IIE7 S1IIE7_ECOLX 1 207
DBREF 6W1Z L 1 207 UNP S1IIE7 S1IIE7_ECOLX 1 207
DBREF 6W1Z M 1 207 UNP S1IIE7 S1IIE7_ECOLX 1 207
DBREF 6W1Z N 1 207 UNP S1IIE7 S1IIE7_ECOLX 1 207
DBREF 6W1Z O 1 207 UNP S1IIE7 S1IIE7_ECOLX 1 207
DBREF 6W1Z P 1 207 UNP S1IIE7 S1IIE7_ECOLX 1 207
DBREF 6W1Z Q 1 207 UNP S1IIE7 S1IIE7_ECOLX 1 207
DBREF 6W1Z R 1 207 UNP S1IIE7 S1IIE7_ECOLX 1 207
DBREF 6W1Z S 1 207 UNP S1IIE7 S1IIE7_ECOLX 1 207
DBREF 6W1Z T 1 207 UNP S1IIE7 S1IIE7_ECOLX 1 207
DBREF 6W1Z A 1 758 UNP P0ABH9 CLPA_ECOLI 1 758
DBREF 6W1Z B 1 758 UNP P0ABH9 CLPA_ECOLI 1 758
DBREF 6W1Z C 1 758 UNP P0ABH9 CLPA_ECOLI 1 758
DBREF 6W1Z D 1 758 UNP P0ABH9 CLPA_ECOLI 1 758
DBREF 6W1Z E 1 758 UNP P0ABH9 CLPA_ECOLI 1 758
DBREF 6W1Z F 1 758 UNP P0ABH9 CLPA_ECOLI 1 758
DBREF 6W1Z X 1 24 PDB 6W1Z 6W1Z 1 24
SEQRES 1 G 207 MET SER TYR SER GLY GLU ARG ASP ASN PHE ALA PRO HIS
SEQRES 2 G 207 MET ALA LEU VAL PRO MET VAL ILE GLU GLN THR SER ARG
SEQRES 3 G 207 GLY GLU ARG SER PHE ASP ILE TYR SER ARG LEU LEU LYS
SEQRES 4 G 207 GLU ARG VAL ILE PHE LEU THR GLY GLN VAL GLU ASP HIS
SEQRES 5 G 207 MET ALA ASN LEU ILE VAL ALA GLN MET LEU PHE LEU GLU
SEQRES 6 G 207 ALA GLU ASN PRO GLU LYS ASP ILE TYR LEU TYR ILE ASN
SEQRES 7 G 207 SER PRO GLY GLY VAL ILE THR ALA GLY MET SER ILE TYR
SEQRES 8 G 207 ASP THR MET GLN PHE ILE LYS PRO ASP VAL SER THR ILE
SEQRES 9 G 207 CYS MET GLY GLN ALA ALA SER MET GLY ALA PHE LEU LEU
SEQRES 10 G 207 THR ALA GLY ALA LYS GLY LYS ARG PHE CYS LEU PRO ASN
SEQRES 11 G 207 SER ARG VAL MET ILE HIS GLN PRO LEU GLY GLY TYR GLN
SEQRES 12 G 207 GLY GLN ALA THR ASP ILE GLU ILE HIS ALA ARG GLU ILE
SEQRES 13 G 207 LEU LYS VAL LYS GLY ARG MET ASN GLU LEU MET ALA LEU
SEQRES 14 G 207 HIS THR GLY GLN SER LEU GLU GLN ILE GLU ARG ASP THR
SEQRES 15 G 207 GLU ARG ASP ARG PHE LEU SER ALA PRO GLU ALA VAL GLU
SEQRES 16 G 207 TYR GLY LEU VAL ASP SER ILE LEU THR HIS ARG ASN
SEQRES 1 H 207 MET SER TYR SER GLY GLU ARG ASP ASN PHE ALA PRO HIS
SEQRES 2 H 207 MET ALA LEU VAL PRO MET VAL ILE GLU GLN THR SER ARG
SEQRES 3 H 207 GLY GLU ARG SER PHE ASP ILE TYR SER ARG LEU LEU LYS
SEQRES 4 H 207 GLU ARG VAL ILE PHE LEU THR GLY GLN VAL GLU ASP HIS
SEQRES 5 H 207 MET ALA ASN LEU ILE VAL ALA GLN MET LEU PHE LEU GLU
SEQRES 6 H 207 ALA GLU ASN PRO GLU LYS ASP ILE TYR LEU TYR ILE ASN
SEQRES 7 H 207 SER PRO GLY GLY VAL ILE THR ALA GLY MET SER ILE TYR
SEQRES 8 H 207 ASP THR MET GLN PHE ILE LYS PRO ASP VAL SER THR ILE
SEQRES 9 H 207 CYS MET GLY GLN ALA ALA SER MET GLY ALA PHE LEU LEU
SEQRES 10 H 207 THR ALA GLY ALA LYS GLY LYS ARG PHE CYS LEU PRO ASN
SEQRES 11 H 207 SER ARG VAL MET ILE HIS GLN PRO LEU GLY GLY TYR GLN
SEQRES 12 H 207 GLY GLN ALA THR ASP ILE GLU ILE HIS ALA ARG GLU ILE
SEQRES 13 H 207 LEU LYS VAL LYS GLY ARG MET ASN GLU LEU MET ALA LEU
SEQRES 14 H 207 HIS THR GLY GLN SER LEU GLU GLN ILE GLU ARG ASP THR
SEQRES 15 H 207 GLU ARG ASP ARG PHE LEU SER ALA PRO GLU ALA VAL GLU
SEQRES 16 H 207 TYR GLY LEU VAL ASP SER ILE LEU THR HIS ARG ASN
SEQRES 1 I 207 MET SER TYR SER GLY GLU ARG ASP ASN PHE ALA PRO HIS
SEQRES 2 I 207 MET ALA LEU VAL PRO MET VAL ILE GLU GLN THR SER ARG
SEQRES 3 I 207 GLY GLU ARG SER PHE ASP ILE TYR SER ARG LEU LEU LYS
SEQRES 4 I 207 GLU ARG VAL ILE PHE LEU THR GLY GLN VAL GLU ASP HIS
SEQRES 5 I 207 MET ALA ASN LEU ILE VAL ALA GLN MET LEU PHE LEU GLU
SEQRES 6 I 207 ALA GLU ASN PRO GLU LYS ASP ILE TYR LEU TYR ILE ASN
SEQRES 7 I 207 SER PRO GLY GLY VAL ILE THR ALA GLY MET SER ILE TYR
SEQRES 8 I 207 ASP THR MET GLN PHE ILE LYS PRO ASP VAL SER THR ILE
SEQRES 9 I 207 CYS MET GLY GLN ALA ALA SER MET GLY ALA PHE LEU LEU
SEQRES 10 I 207 THR ALA GLY ALA LYS GLY LYS ARG PHE CYS LEU PRO ASN
SEQRES 11 I 207 SER ARG VAL MET ILE HIS GLN PRO LEU GLY GLY TYR GLN
SEQRES 12 I 207 GLY GLN ALA THR ASP ILE GLU ILE HIS ALA ARG GLU ILE
SEQRES 13 I 207 LEU LYS VAL LYS GLY ARG MET ASN GLU LEU MET ALA LEU
SEQRES 14 I 207 HIS THR GLY GLN SER LEU GLU GLN ILE GLU ARG ASP THR
SEQRES 15 I 207 GLU ARG ASP ARG PHE LEU SER ALA PRO GLU ALA VAL GLU
SEQRES 16 I 207 TYR GLY LEU VAL ASP SER ILE LEU THR HIS ARG ASN
SEQRES 1 J 207 MET SER TYR SER GLY GLU ARG ASP ASN PHE ALA PRO HIS
SEQRES 2 J 207 MET ALA LEU VAL PRO MET VAL ILE GLU GLN THR SER ARG
SEQRES 3 J 207 GLY GLU ARG SER PHE ASP ILE TYR SER ARG LEU LEU LYS
SEQRES 4 J 207 GLU ARG VAL ILE PHE LEU THR GLY GLN VAL GLU ASP HIS
SEQRES 5 J 207 MET ALA ASN LEU ILE VAL ALA GLN MET LEU PHE LEU GLU
SEQRES 6 J 207 ALA GLU ASN PRO GLU LYS ASP ILE TYR LEU TYR ILE ASN
SEQRES 7 J 207 SER PRO GLY GLY VAL ILE THR ALA GLY MET SER ILE TYR
SEQRES 8 J 207 ASP THR MET GLN PHE ILE LYS PRO ASP VAL SER THR ILE
SEQRES 9 J 207 CYS MET GLY GLN ALA ALA SER MET GLY ALA PHE LEU LEU
SEQRES 10 J 207 THR ALA GLY ALA LYS GLY LYS ARG PHE CYS LEU PRO ASN
SEQRES 11 J 207 SER ARG VAL MET ILE HIS GLN PRO LEU GLY GLY TYR GLN
SEQRES 12 J 207 GLY GLN ALA THR ASP ILE GLU ILE HIS ALA ARG GLU ILE
SEQRES 13 J 207 LEU LYS VAL LYS GLY ARG MET ASN GLU LEU MET ALA LEU
SEQRES 14 J 207 HIS THR GLY GLN SER LEU GLU GLN ILE GLU ARG ASP THR
SEQRES 15 J 207 GLU ARG ASP ARG PHE LEU SER ALA PRO GLU ALA VAL GLU
SEQRES 16 J 207 TYR GLY LEU VAL ASP SER ILE LEU THR HIS ARG ASN
SEQRES 1 K 207 MET SER TYR SER GLY GLU ARG ASP ASN PHE ALA PRO HIS
SEQRES 2 K 207 MET ALA LEU VAL PRO MET VAL ILE GLU GLN THR SER ARG
SEQRES 3 K 207 GLY GLU ARG SER PHE ASP ILE TYR SER ARG LEU LEU LYS
SEQRES 4 K 207 GLU ARG VAL ILE PHE LEU THR GLY GLN VAL GLU ASP HIS
SEQRES 5 K 207 MET ALA ASN LEU ILE VAL ALA GLN MET LEU PHE LEU GLU
SEQRES 6 K 207 ALA GLU ASN PRO GLU LYS ASP ILE TYR LEU TYR ILE ASN
SEQRES 7 K 207 SER PRO GLY GLY VAL ILE THR ALA GLY MET SER ILE TYR
SEQRES 8 K 207 ASP THR MET GLN PHE ILE LYS PRO ASP VAL SER THR ILE
SEQRES 9 K 207 CYS MET GLY GLN ALA ALA SER MET GLY ALA PHE LEU LEU
SEQRES 10 K 207 THR ALA GLY ALA LYS GLY LYS ARG PHE CYS LEU PRO ASN
SEQRES 11 K 207 SER ARG VAL MET ILE HIS GLN PRO LEU GLY GLY TYR GLN
SEQRES 12 K 207 GLY GLN ALA THR ASP ILE GLU ILE HIS ALA ARG GLU ILE
SEQRES 13 K 207 LEU LYS VAL LYS GLY ARG MET ASN GLU LEU MET ALA LEU
SEQRES 14 K 207 HIS THR GLY GLN SER LEU GLU GLN ILE GLU ARG ASP THR
SEQRES 15 K 207 GLU ARG ASP ARG PHE LEU SER ALA PRO GLU ALA VAL GLU
SEQRES 16 K 207 TYR GLY LEU VAL ASP SER ILE LEU THR HIS ARG ASN
SEQRES 1 L 207 MET SER TYR SER GLY GLU ARG ASP ASN PHE ALA PRO HIS
SEQRES 2 L 207 MET ALA LEU VAL PRO MET VAL ILE GLU GLN THR SER ARG
SEQRES 3 L 207 GLY GLU ARG SER PHE ASP ILE TYR SER ARG LEU LEU LYS
SEQRES 4 L 207 GLU ARG VAL ILE PHE LEU THR GLY GLN VAL GLU ASP HIS
SEQRES 5 L 207 MET ALA ASN LEU ILE VAL ALA GLN MET LEU PHE LEU GLU
SEQRES 6 L 207 ALA GLU ASN PRO GLU LYS ASP ILE TYR LEU TYR ILE ASN
SEQRES 7 L 207 SER PRO GLY GLY VAL ILE THR ALA GLY MET SER ILE TYR
SEQRES 8 L 207 ASP THR MET GLN PHE ILE LYS PRO ASP VAL SER THR ILE
SEQRES 9 L 207 CYS MET GLY GLN ALA ALA SER MET GLY ALA PHE LEU LEU
SEQRES 10 L 207 THR ALA GLY ALA LYS GLY LYS ARG PHE CYS LEU PRO ASN
SEQRES 11 L 207 SER ARG VAL MET ILE HIS GLN PRO LEU GLY GLY TYR GLN
SEQRES 12 L 207 GLY GLN ALA THR ASP ILE GLU ILE HIS ALA ARG GLU ILE
SEQRES 13 L 207 LEU LYS VAL LYS GLY ARG MET ASN GLU LEU MET ALA LEU
SEQRES 14 L 207 HIS THR GLY GLN SER LEU GLU GLN ILE GLU ARG ASP THR
SEQRES 15 L 207 GLU ARG ASP ARG PHE LEU SER ALA PRO GLU ALA VAL GLU
SEQRES 16 L 207 TYR GLY LEU VAL ASP SER ILE LEU THR HIS ARG ASN
SEQRES 1 M 207 MET SER TYR SER GLY GLU ARG ASP ASN PHE ALA PRO HIS
SEQRES 2 M 207 MET ALA LEU VAL PRO MET VAL ILE GLU GLN THR SER ARG
SEQRES 3 M 207 GLY GLU ARG SER PHE ASP ILE TYR SER ARG LEU LEU LYS
SEQRES 4 M 207 GLU ARG VAL ILE PHE LEU THR GLY GLN VAL GLU ASP HIS
SEQRES 5 M 207 MET ALA ASN LEU ILE VAL ALA GLN MET LEU PHE LEU GLU
SEQRES 6 M 207 ALA GLU ASN PRO GLU LYS ASP ILE TYR LEU TYR ILE ASN
SEQRES 7 M 207 SER PRO GLY GLY VAL ILE THR ALA GLY MET SER ILE TYR
SEQRES 8 M 207 ASP THR MET GLN PHE ILE LYS PRO ASP VAL SER THR ILE
SEQRES 9 M 207 CYS MET GLY GLN ALA ALA SER MET GLY ALA PHE LEU LEU
SEQRES 10 M 207 THR ALA GLY ALA LYS GLY LYS ARG PHE CYS LEU PRO ASN
SEQRES 11 M 207 SER ARG VAL MET ILE HIS GLN PRO LEU GLY GLY TYR GLN
SEQRES 12 M 207 GLY GLN ALA THR ASP ILE GLU ILE HIS ALA ARG GLU ILE
SEQRES 13 M 207 LEU LYS VAL LYS GLY ARG MET ASN GLU LEU MET ALA LEU
SEQRES 14 M 207 HIS THR GLY GLN SER LEU GLU GLN ILE GLU ARG ASP THR
SEQRES 15 M 207 GLU ARG ASP ARG PHE LEU SER ALA PRO GLU ALA VAL GLU
SEQRES 16 M 207 TYR GLY LEU VAL ASP SER ILE LEU THR HIS ARG ASN
SEQRES 1 N 207 MET SER TYR SER GLY GLU ARG ASP ASN PHE ALA PRO HIS
SEQRES 2 N 207 MET ALA LEU VAL PRO MET VAL ILE GLU GLN THR SER ARG
SEQRES 3 N 207 GLY GLU ARG SER PHE ASP ILE TYR SER ARG LEU LEU LYS
SEQRES 4 N 207 GLU ARG VAL ILE PHE LEU THR GLY GLN VAL GLU ASP HIS
SEQRES 5 N 207 MET ALA ASN LEU ILE VAL ALA GLN MET LEU PHE LEU GLU
SEQRES 6 N 207 ALA GLU ASN PRO GLU LYS ASP ILE TYR LEU TYR ILE ASN
SEQRES 7 N 207 SER PRO GLY GLY VAL ILE THR ALA GLY MET SER ILE TYR
SEQRES 8 N 207 ASP THR MET GLN PHE ILE LYS PRO ASP VAL SER THR ILE
SEQRES 9 N 207 CYS MET GLY GLN ALA ALA SER MET GLY ALA PHE LEU LEU
SEQRES 10 N 207 THR ALA GLY ALA LYS GLY LYS ARG PHE CYS LEU PRO ASN
SEQRES 11 N 207 SER ARG VAL MET ILE HIS GLN PRO LEU GLY GLY TYR GLN
SEQRES 12 N 207 GLY GLN ALA THR ASP ILE GLU ILE HIS ALA ARG GLU ILE
SEQRES 13 N 207 LEU LYS VAL LYS GLY ARG MET ASN GLU LEU MET ALA LEU
SEQRES 14 N 207 HIS THR GLY GLN SER LEU GLU GLN ILE GLU ARG ASP THR
SEQRES 15 N 207 GLU ARG ASP ARG PHE LEU SER ALA PRO GLU ALA VAL GLU
SEQRES 16 N 207 TYR GLY LEU VAL ASP SER ILE LEU THR HIS ARG ASN
SEQRES 1 O 207 MET SER TYR SER GLY GLU ARG ASP ASN PHE ALA PRO HIS
SEQRES 2 O 207 MET ALA LEU VAL PRO MET VAL ILE GLU GLN THR SER ARG
SEQRES 3 O 207 GLY GLU ARG SER PHE ASP ILE TYR SER ARG LEU LEU LYS
SEQRES 4 O 207 GLU ARG VAL ILE PHE LEU THR GLY GLN VAL GLU ASP HIS
SEQRES 5 O 207 MET ALA ASN LEU ILE VAL ALA GLN MET LEU PHE LEU GLU
SEQRES 6 O 207 ALA GLU ASN PRO GLU LYS ASP ILE TYR LEU TYR ILE ASN
SEQRES 7 O 207 SER PRO GLY GLY VAL ILE THR ALA GLY MET SER ILE TYR
SEQRES 8 O 207 ASP THR MET GLN PHE ILE LYS PRO ASP VAL SER THR ILE
SEQRES 9 O 207 CYS MET GLY GLN ALA ALA SER MET GLY ALA PHE LEU LEU
SEQRES 10 O 207 THR ALA GLY ALA LYS GLY LYS ARG PHE CYS LEU PRO ASN
SEQRES 11 O 207 SER ARG VAL MET ILE HIS GLN PRO LEU GLY GLY TYR GLN
SEQRES 12 O 207 GLY GLN ALA THR ASP ILE GLU ILE HIS ALA ARG GLU ILE
SEQRES 13 O 207 LEU LYS VAL LYS GLY ARG MET ASN GLU LEU MET ALA LEU
SEQRES 14 O 207 HIS THR GLY GLN SER LEU GLU GLN ILE GLU ARG ASP THR
SEQRES 15 O 207 GLU ARG ASP ARG PHE LEU SER ALA PRO GLU ALA VAL GLU
SEQRES 16 O 207 TYR GLY LEU VAL ASP SER ILE LEU THR HIS ARG ASN
SEQRES 1 P 207 MET SER TYR SER GLY GLU ARG ASP ASN PHE ALA PRO HIS
SEQRES 2 P 207 MET ALA LEU VAL PRO MET VAL ILE GLU GLN THR SER ARG
SEQRES 3 P 207 GLY GLU ARG SER PHE ASP ILE TYR SER ARG LEU LEU LYS
SEQRES 4 P 207 GLU ARG VAL ILE PHE LEU THR GLY GLN VAL GLU ASP HIS
SEQRES 5 P 207 MET ALA ASN LEU ILE VAL ALA GLN MET LEU PHE LEU GLU
SEQRES 6 P 207 ALA GLU ASN PRO GLU LYS ASP ILE TYR LEU TYR ILE ASN
SEQRES 7 P 207 SER PRO GLY GLY VAL ILE THR ALA GLY MET SER ILE TYR
SEQRES 8 P 207 ASP THR MET GLN PHE ILE LYS PRO ASP VAL SER THR ILE
SEQRES 9 P 207 CYS MET GLY GLN ALA ALA SER MET GLY ALA PHE LEU LEU
SEQRES 10 P 207 THR ALA GLY ALA LYS GLY LYS ARG PHE CYS LEU PRO ASN
SEQRES 11 P 207 SER ARG VAL MET ILE HIS GLN PRO LEU GLY GLY TYR GLN
SEQRES 12 P 207 GLY GLN ALA THR ASP ILE GLU ILE HIS ALA ARG GLU ILE
SEQRES 13 P 207 LEU LYS VAL LYS GLY ARG MET ASN GLU LEU MET ALA LEU
SEQRES 14 P 207 HIS THR GLY GLN SER LEU GLU GLN ILE GLU ARG ASP THR
SEQRES 15 P 207 GLU ARG ASP ARG PHE LEU SER ALA PRO GLU ALA VAL GLU
SEQRES 16 P 207 TYR GLY LEU VAL ASP SER ILE LEU THR HIS ARG ASN
SEQRES 1 Q 207 MET SER TYR SER GLY GLU ARG ASP ASN PHE ALA PRO HIS
SEQRES 2 Q 207 MET ALA LEU VAL PRO MET VAL ILE GLU GLN THR SER ARG
SEQRES 3 Q 207 GLY GLU ARG SER PHE ASP ILE TYR SER ARG LEU LEU LYS
SEQRES 4 Q 207 GLU ARG VAL ILE PHE LEU THR GLY GLN VAL GLU ASP HIS
SEQRES 5 Q 207 MET ALA ASN LEU ILE VAL ALA GLN MET LEU PHE LEU GLU
SEQRES 6 Q 207 ALA GLU ASN PRO GLU LYS ASP ILE TYR LEU TYR ILE ASN
SEQRES 7 Q 207 SER PRO GLY GLY VAL ILE THR ALA GLY MET SER ILE TYR
SEQRES 8 Q 207 ASP THR MET GLN PHE ILE LYS PRO ASP VAL SER THR ILE
SEQRES 9 Q 207 CYS MET GLY GLN ALA ALA SER MET GLY ALA PHE LEU LEU
SEQRES 10 Q 207 THR ALA GLY ALA LYS GLY LYS ARG PHE CYS LEU PRO ASN
SEQRES 11 Q 207 SER ARG VAL MET ILE HIS GLN PRO LEU GLY GLY TYR GLN
SEQRES 12 Q 207 GLY GLN ALA THR ASP ILE GLU ILE HIS ALA ARG GLU ILE
SEQRES 13 Q 207 LEU LYS VAL LYS GLY ARG MET ASN GLU LEU MET ALA LEU
SEQRES 14 Q 207 HIS THR GLY GLN SER LEU GLU GLN ILE GLU ARG ASP THR
SEQRES 15 Q 207 GLU ARG ASP ARG PHE LEU SER ALA PRO GLU ALA VAL GLU
SEQRES 16 Q 207 TYR GLY LEU VAL ASP SER ILE LEU THR HIS ARG ASN
SEQRES 1 R 207 MET SER TYR SER GLY GLU ARG ASP ASN PHE ALA PRO HIS
SEQRES 2 R 207 MET ALA LEU VAL PRO MET VAL ILE GLU GLN THR SER ARG
SEQRES 3 R 207 GLY GLU ARG SER PHE ASP ILE TYR SER ARG LEU LEU LYS
SEQRES 4 R 207 GLU ARG VAL ILE PHE LEU THR GLY GLN VAL GLU ASP HIS
SEQRES 5 R 207 MET ALA ASN LEU ILE VAL ALA GLN MET LEU PHE LEU GLU
SEQRES 6 R 207 ALA GLU ASN PRO GLU LYS ASP ILE TYR LEU TYR ILE ASN
SEQRES 7 R 207 SER PRO GLY GLY VAL ILE THR ALA GLY MET SER ILE TYR
SEQRES 8 R 207 ASP THR MET GLN PHE ILE LYS PRO ASP VAL SER THR ILE
SEQRES 9 R 207 CYS MET GLY GLN ALA ALA SER MET GLY ALA PHE LEU LEU
SEQRES 10 R 207 THR ALA GLY ALA LYS GLY LYS ARG PHE CYS LEU PRO ASN
SEQRES 11 R 207 SER ARG VAL MET ILE HIS GLN PRO LEU GLY GLY TYR GLN
SEQRES 12 R 207 GLY GLN ALA THR ASP ILE GLU ILE HIS ALA ARG GLU ILE
SEQRES 13 R 207 LEU LYS VAL LYS GLY ARG MET ASN GLU LEU MET ALA LEU
SEQRES 14 R 207 HIS THR GLY GLN SER LEU GLU GLN ILE GLU ARG ASP THR
SEQRES 15 R 207 GLU ARG ASP ARG PHE LEU SER ALA PRO GLU ALA VAL GLU
SEQRES 16 R 207 TYR GLY LEU VAL ASP SER ILE LEU THR HIS ARG ASN
SEQRES 1 S 207 MET SER TYR SER GLY GLU ARG ASP ASN PHE ALA PRO HIS
SEQRES 2 S 207 MET ALA LEU VAL PRO MET VAL ILE GLU GLN THR SER ARG
SEQRES 3 S 207 GLY GLU ARG SER PHE ASP ILE TYR SER ARG LEU LEU LYS
SEQRES 4 S 207 GLU ARG VAL ILE PHE LEU THR GLY GLN VAL GLU ASP HIS
SEQRES 5 S 207 MET ALA ASN LEU ILE VAL ALA GLN MET LEU PHE LEU GLU
SEQRES 6 S 207 ALA GLU ASN PRO GLU LYS ASP ILE TYR LEU TYR ILE ASN
SEQRES 7 S 207 SER PRO GLY GLY VAL ILE THR ALA GLY MET SER ILE TYR
SEQRES 8 S 207 ASP THR MET GLN PHE ILE LYS PRO ASP VAL SER THR ILE
SEQRES 9 S 207 CYS MET GLY GLN ALA ALA SER MET GLY ALA PHE LEU LEU
SEQRES 10 S 207 THR ALA GLY ALA LYS GLY LYS ARG PHE CYS LEU PRO ASN
SEQRES 11 S 207 SER ARG VAL MET ILE HIS GLN PRO LEU GLY GLY TYR GLN
SEQRES 12 S 207 GLY GLN ALA THR ASP ILE GLU ILE HIS ALA ARG GLU ILE
SEQRES 13 S 207 LEU LYS VAL LYS GLY ARG MET ASN GLU LEU MET ALA LEU
SEQRES 14 S 207 HIS THR GLY GLN SER LEU GLU GLN ILE GLU ARG ASP THR
SEQRES 15 S 207 GLU ARG ASP ARG PHE LEU SER ALA PRO GLU ALA VAL GLU
SEQRES 16 S 207 TYR GLY LEU VAL ASP SER ILE LEU THR HIS ARG ASN
SEQRES 1 T 207 MET SER TYR SER GLY GLU ARG ASP ASN PHE ALA PRO HIS
SEQRES 2 T 207 MET ALA LEU VAL PRO MET VAL ILE GLU GLN THR SER ARG
SEQRES 3 T 207 GLY GLU ARG SER PHE ASP ILE TYR SER ARG LEU LEU LYS
SEQRES 4 T 207 GLU ARG VAL ILE PHE LEU THR GLY GLN VAL GLU ASP HIS
SEQRES 5 T 207 MET ALA ASN LEU ILE VAL ALA GLN MET LEU PHE LEU GLU
SEQRES 6 T 207 ALA GLU ASN PRO GLU LYS ASP ILE TYR LEU TYR ILE ASN
SEQRES 7 T 207 SER PRO GLY GLY VAL ILE THR ALA GLY MET SER ILE TYR
SEQRES 8 T 207 ASP THR MET GLN PHE ILE LYS PRO ASP VAL SER THR ILE
SEQRES 9 T 207 CYS MET GLY GLN ALA ALA SER MET GLY ALA PHE LEU LEU
SEQRES 10 T 207 THR ALA GLY ALA LYS GLY LYS ARG PHE CYS LEU PRO ASN
SEQRES 11 T 207 SER ARG VAL MET ILE HIS GLN PRO LEU GLY GLY TYR GLN
SEQRES 12 T 207 GLY GLN ALA THR ASP ILE GLU ILE HIS ALA ARG GLU ILE
SEQRES 13 T 207 LEU LYS VAL LYS GLY ARG MET ASN GLU LEU MET ALA LEU
SEQRES 14 T 207 HIS THR GLY GLN SER LEU GLU GLN ILE GLU ARG ASP THR
SEQRES 15 T 207 GLU ARG ASP ARG PHE LEU SER ALA PRO GLU ALA VAL GLU
SEQRES 16 T 207 TYR GLY LEU VAL ASP SER ILE LEU THR HIS ARG ASN
SEQRES 1 A 758 MET LEU ASN GLN GLU LEU GLU LEU SER LEU ASN MET ALA
SEQRES 2 A 758 PHE ALA ARG ALA ARG GLU HIS ARG HIS GLU PHE MET THR
SEQRES 3 A 758 VAL GLU HIS LEU LEU LEU ALA LEU LEU SER ASN PRO SER
SEQRES 4 A 758 ALA ARG GLU ALA LEU GLU ALA CYS SER VAL ASP LEU VAL
SEQRES 5 A 758 ALA LEU ARG GLN GLU LEU GLU ALA PHE ILE GLU GLN THR
SEQRES 6 A 758 THR PRO VAL LEU PRO ALA SER GLU GLU GLU ARG ASP THR
SEQRES 7 A 758 GLN PRO THR LEU SER PHE GLN ARG VAL LEU GLN ARG ALA
SEQRES 8 A 758 VAL PHE HIS VAL GLN SER SER GLY ARG ASN GLU VAL THR
SEQRES 9 A 758 GLY ALA ASN VAL LEU VAL ALA ILE PHE SER GLU GLN GLU
SEQRES 10 A 758 SER GLN ALA ALA TYR LEU LEU ARG LYS HIS GLU VAL SER
SEQRES 11 A 758 ARG LEU ASP VAL VAL ASN PHE ILE SER HIS GLY THR ARG
SEQRES 12 A 758 LYS ASP GLU PRO THR GLN SER SER ASP PRO GLY SER GLN
SEQRES 13 A 758 PRO ASN SER GLU GLU GLN ALA GLY GLY GLU GLU ARG MET
SEQRES 14 A 758 GLU ASN PHE THR THR ASN LEU ASN GLN LEU ALA ARG VAL
SEQRES 15 A 758 GLY GLY ILE ASP PRO LEU ILE GLY ARG GLU LYS GLU LEU
SEQRES 16 A 758 GLU ARG ALA ILE GLN VAL LEU CYS ARG ARG ARG LYS ASN
SEQRES 17 A 758 ASN PRO LEU LEU VAL GLY GLU SER GLY VAL GLY LYS THR
SEQRES 18 A 758 ALA ILE ALA GLU GLY LEU ALA TRP ARG ILE VAL GLN GLY
SEQRES 19 A 758 ASP VAL PRO GLU VAL MET ALA ASP CYS THR ILE TYR SER
SEQRES 20 A 758 LEU ASP ILE GLY SER LEU LEU ALA GLY THR LYS TYR ARG
SEQRES 21 A 758 GLY ASP PHE GLU LYS ARG PHE LYS ALA LEU LEU LYS GLN
SEQRES 22 A 758 LEU GLU GLN ASP THR ASN SER ILE LEU PHE ILE ASP GLU
SEQRES 23 A 758 ILE HIS THR ILE ILE GLY ALA GLY ALA ALA SER GLY GLY
SEQRES 24 A 758 GLN VAL ASP ALA ALA ASN LEU ILE LYS PRO LEU LEU SER
SEQRES 25 A 758 SER GLY LYS ILE ARG VAL ILE GLY SER THR THR TYR GLN
SEQRES 26 A 758 GLU PHE SER ASN ILE PHE GLU LYS ASP ARG ALA LEU ALA
SEQRES 27 A 758 ARG ARG PHE GLN LYS ILE ASP ILE THR GLU PRO SER ILE
SEQRES 28 A 758 GLU GLU THR VAL GLN ILE ILE ASN GLY LEU LYS PRO LYS
SEQRES 29 A 758 TYR GLU ALA HIS HIS ASP VAL ARG TYR THR ALA LYS ALA
SEQRES 30 A 758 VAL ARG ALA ALA VAL GLU LEU ALA VAL LYS TYR ILE ASN
SEQRES 31 A 758 ASP ARG HIS LEU PRO ASP LYS ALA ILE ASP VAL ILE ASP
SEQRES 32 A 758 GLU ALA GLY ALA ARG ALA ARG LEU MET PRO VAL SER LYS
SEQRES 33 A 758 ARG LYS LYS THR VAL ASN VAL ALA ASP ILE GLU SER VAL
SEQRES 34 A 758 VAL ALA ARG ILE ALA ARG ILE PRO GLU LYS SER VAL SER
SEQRES 35 A 758 GLN SER ASP ARG ASP THR LEU LYS ASN LEU GLY ASP ARG
SEQRES 36 A 758 LEU LYS MET LEU VAL PHE GLY GLN ASP LYS ALA ILE GLU
SEQRES 37 A 758 ALA LEU THR GLU ALA ILE LYS MET ALA ARG ALA GLY LEU
SEQRES 38 A 758 GLY HIS GLU HIS LYS PRO VAL GLY SER PHE LEU PHE ALA
SEQRES 39 A 758 GLY PRO THR GLY VAL GLY LYS THR GLU VAL THR VAL GLN
SEQRES 40 A 758 LEU SER LYS ALA LEU GLY ILE GLU LEU LEU ARG PHE ASP
SEQRES 41 A 758 MET SER GLU TYR MET GLU ARG HIS THR VAL SER ARG LEU
SEQRES 42 A 758 ILE GLY ALA PRO PRO GLY TYR VAL GLY PHE ASP GLN GLY
SEQRES 43 A 758 GLY LEU LEU THR ASP ALA VAL ILE LYS HIS PRO HIS ALA
SEQRES 44 A 758 VAL LEU LEU LEU ASP GLU ILE GLU LYS ALA HIS PRO ASP
SEQRES 45 A 758 VAL PHE ASN ILE LEU LEU GLN VAL MET ASP ASN GLY THR
SEQRES 46 A 758 LEU THR ASP ASN ASN GLY ARG LYS ALA ASP PHE ARG ASN
SEQRES 47 A 758 VAL VAL LEU VAL MET THR THR ASN ALA GLY VAL ARG GLU
SEQRES 48 A 758 THR GLU ARG LYS SER ILE GLY LEU ILE HIS GLN ASP ASN
SEQRES 49 A 758 SER THR ASP ALA MET GLU GLU ILE LYS LYS ILE PHE THR
SEQRES 50 A 758 PRO GLU PHE ARG ASN ARG LEU ASP ASN ILE ILE TRP PHE
SEQRES 51 A 758 ASP HIS LEU SER THR ASP VAL ILE HIS GLN VAL VAL ASP
SEQRES 52 A 758 LYS PHE ILE VAL GLU LEU GLN VAL GLN LEU ASP GLN LYS
SEQRES 53 A 758 GLY VAL SER LEU GLU VAL SER GLN GLU ALA ARG ASN TRP
SEQRES 54 A 758 LEU ALA GLU LYS GLY TYR ASP ARG ALA MET GLY ALA ARG
SEQRES 55 A 758 PRO MET ALA ARG VAL ILE GLN ASP ASN LEU LYS LYS PRO
SEQRES 56 A 758 LEU ALA ASN GLU LEU LEU PHE GLY SER LEU VAL ASP GLY
SEQRES 57 A 758 GLY GLN VAL THR VAL ALA LEU ASP LYS GLU LYS ASN GLU
SEQRES 58 A 758 LEU THR TYR GLY PHE GLN SER ALA GLN LYS HIS LYS ALA
SEQRES 59 A 758 GLU ALA ALA HIS
SEQRES 1 B 758 MET LEU ASN GLN GLU LEU GLU LEU SER LEU ASN MET ALA
SEQRES 2 B 758 PHE ALA ARG ALA ARG GLU HIS ARG HIS GLU PHE MET THR
SEQRES 3 B 758 VAL GLU HIS LEU LEU LEU ALA LEU LEU SER ASN PRO SER
SEQRES 4 B 758 ALA ARG GLU ALA LEU GLU ALA CYS SER VAL ASP LEU VAL
SEQRES 5 B 758 ALA LEU ARG GLN GLU LEU GLU ALA PHE ILE GLU GLN THR
SEQRES 6 B 758 THR PRO VAL LEU PRO ALA SER GLU GLU GLU ARG ASP THR
SEQRES 7 B 758 GLN PRO THR LEU SER PHE GLN ARG VAL LEU GLN ARG ALA
SEQRES 8 B 758 VAL PHE HIS VAL GLN SER SER GLY ARG ASN GLU VAL THR
SEQRES 9 B 758 GLY ALA ASN VAL LEU VAL ALA ILE PHE SER GLU GLN GLU
SEQRES 10 B 758 SER GLN ALA ALA TYR LEU LEU ARG LYS HIS GLU VAL SER
SEQRES 11 B 758 ARG LEU ASP VAL VAL ASN PHE ILE SER HIS GLY THR ARG
SEQRES 12 B 758 LYS ASP GLU PRO THR GLN SER SER ASP PRO GLY SER GLN
SEQRES 13 B 758 PRO ASN SER GLU GLU GLN ALA GLY GLY GLU GLU ARG MET
SEQRES 14 B 758 GLU ASN PHE THR THR ASN LEU ASN GLN LEU ALA ARG VAL
SEQRES 15 B 758 GLY GLY ILE ASP PRO LEU ILE GLY ARG GLU LYS GLU LEU
SEQRES 16 B 758 GLU ARG ALA ILE GLN VAL LEU CYS ARG ARG ARG LYS ASN
SEQRES 17 B 758 ASN PRO LEU LEU VAL GLY GLU SER GLY VAL GLY LYS THR
SEQRES 18 B 758 ALA ILE ALA GLU GLY LEU ALA TRP ARG ILE VAL GLN GLY
SEQRES 19 B 758 ASP VAL PRO GLU VAL MET ALA ASP CYS THR ILE TYR SER
SEQRES 20 B 758 LEU ASP ILE GLY SER LEU LEU ALA GLY THR LYS TYR ARG
SEQRES 21 B 758 GLY ASP PHE GLU LYS ARG PHE LYS ALA LEU LEU LYS GLN
SEQRES 22 B 758 LEU GLU GLN ASP THR ASN SER ILE LEU PHE ILE ASP GLU
SEQRES 23 B 758 ILE HIS THR ILE ILE GLY ALA GLY ALA ALA SER GLY GLY
SEQRES 24 B 758 GLN VAL ASP ALA ALA ASN LEU ILE LYS PRO LEU LEU SER
SEQRES 25 B 758 SER GLY LYS ILE ARG VAL ILE GLY SER THR THR TYR GLN
SEQRES 26 B 758 GLU PHE SER ASN ILE PHE GLU LYS ASP ARG ALA LEU ALA
SEQRES 27 B 758 ARG ARG PHE GLN LYS ILE ASP ILE THR GLU PRO SER ILE
SEQRES 28 B 758 GLU GLU THR VAL GLN ILE ILE ASN GLY LEU LYS PRO LYS
SEQRES 29 B 758 TYR GLU ALA HIS HIS ASP VAL ARG TYR THR ALA LYS ALA
SEQRES 30 B 758 VAL ARG ALA ALA VAL GLU LEU ALA VAL LYS TYR ILE ASN
SEQRES 31 B 758 ASP ARG HIS LEU PRO ASP LYS ALA ILE ASP VAL ILE ASP
SEQRES 32 B 758 GLU ALA GLY ALA ARG ALA ARG LEU MET PRO VAL SER LYS
SEQRES 33 B 758 ARG LYS LYS THR VAL ASN VAL ALA ASP ILE GLU SER VAL
SEQRES 34 B 758 VAL ALA ARG ILE ALA ARG ILE PRO GLU LYS SER VAL SER
SEQRES 35 B 758 GLN SER ASP ARG ASP THR LEU LYS ASN LEU GLY ASP ARG
SEQRES 36 B 758 LEU LYS MET LEU VAL PHE GLY GLN ASP LYS ALA ILE GLU
SEQRES 37 B 758 ALA LEU THR GLU ALA ILE LYS MET ALA ARG ALA GLY LEU
SEQRES 38 B 758 GLY HIS GLU HIS LYS PRO VAL GLY SER PHE LEU PHE ALA
SEQRES 39 B 758 GLY PRO THR GLY VAL GLY LYS THR GLU VAL THR VAL GLN
SEQRES 40 B 758 LEU SER LYS ALA LEU GLY ILE GLU LEU LEU ARG PHE ASP
SEQRES 41 B 758 MET SER GLU TYR MET GLU ARG HIS THR VAL SER ARG LEU
SEQRES 42 B 758 ILE GLY ALA PRO PRO GLY TYR VAL GLY PHE ASP GLN GLY
SEQRES 43 B 758 GLY LEU LEU THR ASP ALA VAL ILE LYS HIS PRO HIS ALA
SEQRES 44 B 758 VAL LEU LEU LEU ASP GLU ILE GLU LYS ALA HIS PRO ASP
SEQRES 45 B 758 VAL PHE ASN ILE LEU LEU GLN VAL MET ASP ASN GLY THR
SEQRES 46 B 758 LEU THR ASP ASN ASN GLY ARG LYS ALA ASP PHE ARG ASN
SEQRES 47 B 758 VAL VAL LEU VAL MET THR THR ASN ALA GLY VAL ARG GLU
SEQRES 48 B 758 THR GLU ARG LYS SER ILE GLY LEU ILE HIS GLN ASP ASN
SEQRES 49 B 758 SER THR ASP ALA MET GLU GLU ILE LYS LYS ILE PHE THR
SEQRES 50 B 758 PRO GLU PHE ARG ASN ARG LEU ASP ASN ILE ILE TRP PHE
SEQRES 51 B 758 ASP HIS LEU SER THR ASP VAL ILE HIS GLN VAL VAL ASP
SEQRES 52 B 758 LYS PHE ILE VAL GLU LEU GLN VAL GLN LEU ASP GLN LYS
SEQRES 53 B 758 GLY VAL SER LEU GLU VAL SER GLN GLU ALA ARG ASN TRP
SEQRES 54 B 758 LEU ALA GLU LYS GLY TYR ASP ARG ALA MET GLY ALA ARG
SEQRES 55 B 758 PRO MET ALA ARG VAL ILE GLN ASP ASN LEU LYS LYS PRO
SEQRES 56 B 758 LEU ALA ASN GLU LEU LEU PHE GLY SER LEU VAL ASP GLY
SEQRES 57 B 758 GLY GLN VAL THR VAL ALA LEU ASP LYS GLU LYS ASN GLU
SEQRES 58 B 758 LEU THR TYR GLY PHE GLN SER ALA GLN LYS HIS LYS ALA
SEQRES 59 B 758 GLU ALA ALA HIS
SEQRES 1 C 758 MET LEU ASN GLN GLU LEU GLU LEU SER LEU ASN MET ALA
SEQRES 2 C 758 PHE ALA ARG ALA ARG GLU HIS ARG HIS GLU PHE MET THR
SEQRES 3 C 758 VAL GLU HIS LEU LEU LEU ALA LEU LEU SER ASN PRO SER
SEQRES 4 C 758 ALA ARG GLU ALA LEU GLU ALA CYS SER VAL ASP LEU VAL
SEQRES 5 C 758 ALA LEU ARG GLN GLU LEU GLU ALA PHE ILE GLU GLN THR
SEQRES 6 C 758 THR PRO VAL LEU PRO ALA SER GLU GLU GLU ARG ASP THR
SEQRES 7 C 758 GLN PRO THR LEU SER PHE GLN ARG VAL LEU GLN ARG ALA
SEQRES 8 C 758 VAL PHE HIS VAL GLN SER SER GLY ARG ASN GLU VAL THR
SEQRES 9 C 758 GLY ALA ASN VAL LEU VAL ALA ILE PHE SER GLU GLN GLU
SEQRES 10 C 758 SER GLN ALA ALA TYR LEU LEU ARG LYS HIS GLU VAL SER
SEQRES 11 C 758 ARG LEU ASP VAL VAL ASN PHE ILE SER HIS GLY THR ARG
SEQRES 12 C 758 LYS ASP GLU PRO THR GLN SER SER ASP PRO GLY SER GLN
SEQRES 13 C 758 PRO ASN SER GLU GLU GLN ALA GLY GLY GLU GLU ARG MET
SEQRES 14 C 758 GLU ASN PHE THR THR ASN LEU ASN GLN LEU ALA ARG VAL
SEQRES 15 C 758 GLY GLY ILE ASP PRO LEU ILE GLY ARG GLU LYS GLU LEU
SEQRES 16 C 758 GLU ARG ALA ILE GLN VAL LEU CYS ARG ARG ARG LYS ASN
SEQRES 17 C 758 ASN PRO LEU LEU VAL GLY GLU SER GLY VAL GLY LYS THR
SEQRES 18 C 758 ALA ILE ALA GLU GLY LEU ALA TRP ARG ILE VAL GLN GLY
SEQRES 19 C 758 ASP VAL PRO GLU VAL MET ALA ASP CYS THR ILE TYR SER
SEQRES 20 C 758 LEU ASP ILE GLY SER LEU LEU ALA GLY THR LYS TYR ARG
SEQRES 21 C 758 GLY ASP PHE GLU LYS ARG PHE LYS ALA LEU LEU LYS GLN
SEQRES 22 C 758 LEU GLU GLN ASP THR ASN SER ILE LEU PHE ILE ASP GLU
SEQRES 23 C 758 ILE HIS THR ILE ILE GLY ALA GLY ALA ALA SER GLY GLY
SEQRES 24 C 758 GLN VAL ASP ALA ALA ASN LEU ILE LYS PRO LEU LEU SER
SEQRES 25 C 758 SER GLY LYS ILE ARG VAL ILE GLY SER THR THR TYR GLN
SEQRES 26 C 758 GLU PHE SER ASN ILE PHE GLU LYS ASP ARG ALA LEU ALA
SEQRES 27 C 758 ARG ARG PHE GLN LYS ILE ASP ILE THR GLU PRO SER ILE
SEQRES 28 C 758 GLU GLU THR VAL GLN ILE ILE ASN GLY LEU LYS PRO LYS
SEQRES 29 C 758 TYR GLU ALA HIS HIS ASP VAL ARG TYR THR ALA LYS ALA
SEQRES 30 C 758 VAL ARG ALA ALA VAL GLU LEU ALA VAL LYS TYR ILE ASN
SEQRES 31 C 758 ASP ARG HIS LEU PRO ASP LYS ALA ILE ASP VAL ILE ASP
SEQRES 32 C 758 GLU ALA GLY ALA ARG ALA ARG LEU MET PRO VAL SER LYS
SEQRES 33 C 758 ARG LYS LYS THR VAL ASN VAL ALA ASP ILE GLU SER VAL
SEQRES 34 C 758 VAL ALA ARG ILE ALA ARG ILE PRO GLU LYS SER VAL SER
SEQRES 35 C 758 GLN SER ASP ARG ASP THR LEU LYS ASN LEU GLY ASP ARG
SEQRES 36 C 758 LEU LYS MET LEU VAL PHE GLY GLN ASP LYS ALA ILE GLU
SEQRES 37 C 758 ALA LEU THR GLU ALA ILE LYS MET ALA ARG ALA GLY LEU
SEQRES 38 C 758 GLY HIS GLU HIS LYS PRO VAL GLY SER PHE LEU PHE ALA
SEQRES 39 C 758 GLY PRO THR GLY VAL GLY LYS THR GLU VAL THR VAL GLN
SEQRES 40 C 758 LEU SER LYS ALA LEU GLY ILE GLU LEU LEU ARG PHE ASP
SEQRES 41 C 758 MET SER GLU TYR MET GLU ARG HIS THR VAL SER ARG LEU
SEQRES 42 C 758 ILE GLY ALA PRO PRO GLY TYR VAL GLY PHE ASP GLN GLY
SEQRES 43 C 758 GLY LEU LEU THR ASP ALA VAL ILE LYS HIS PRO HIS ALA
SEQRES 44 C 758 VAL LEU LEU LEU ASP GLU ILE GLU LYS ALA HIS PRO ASP
SEQRES 45 C 758 VAL PHE ASN ILE LEU LEU GLN VAL MET ASP ASN GLY THR
SEQRES 46 C 758 LEU THR ASP ASN ASN GLY ARG LYS ALA ASP PHE ARG ASN
SEQRES 47 C 758 VAL VAL LEU VAL MET THR THR ASN ALA GLY VAL ARG GLU
SEQRES 48 C 758 THR GLU ARG LYS SER ILE GLY LEU ILE HIS GLN ASP ASN
SEQRES 49 C 758 SER THR ASP ALA MET GLU GLU ILE LYS LYS ILE PHE THR
SEQRES 50 C 758 PRO GLU PHE ARG ASN ARG LEU ASP ASN ILE ILE TRP PHE
SEQRES 51 C 758 ASP HIS LEU SER THR ASP VAL ILE HIS GLN VAL VAL ASP
SEQRES 52 C 758 LYS PHE ILE VAL GLU LEU GLN VAL GLN LEU ASP GLN LYS
SEQRES 53 C 758 GLY VAL SER LEU GLU VAL SER GLN GLU ALA ARG ASN TRP
SEQRES 54 C 758 LEU ALA GLU LYS GLY TYR ASP ARG ALA MET GLY ALA ARG
SEQRES 55 C 758 PRO MET ALA ARG VAL ILE GLN ASP ASN LEU LYS LYS PRO
SEQRES 56 C 758 LEU ALA ASN GLU LEU LEU PHE GLY SER LEU VAL ASP GLY
SEQRES 57 C 758 GLY GLN VAL THR VAL ALA LEU ASP LYS GLU LYS ASN GLU
SEQRES 58 C 758 LEU THR TYR GLY PHE GLN SER ALA GLN LYS HIS LYS ALA
SEQRES 59 C 758 GLU ALA ALA HIS
SEQRES 1 D 758 MET LEU ASN GLN GLU LEU GLU LEU SER LEU ASN MET ALA
SEQRES 2 D 758 PHE ALA ARG ALA ARG GLU HIS ARG HIS GLU PHE MET THR
SEQRES 3 D 758 VAL GLU HIS LEU LEU LEU ALA LEU LEU SER ASN PRO SER
SEQRES 4 D 758 ALA ARG GLU ALA LEU GLU ALA CYS SER VAL ASP LEU VAL
SEQRES 5 D 758 ALA LEU ARG GLN GLU LEU GLU ALA PHE ILE GLU GLN THR
SEQRES 6 D 758 THR PRO VAL LEU PRO ALA SER GLU GLU GLU ARG ASP THR
SEQRES 7 D 758 GLN PRO THR LEU SER PHE GLN ARG VAL LEU GLN ARG ALA
SEQRES 8 D 758 VAL PHE HIS VAL GLN SER SER GLY ARG ASN GLU VAL THR
SEQRES 9 D 758 GLY ALA ASN VAL LEU VAL ALA ILE PHE SER GLU GLN GLU
SEQRES 10 D 758 SER GLN ALA ALA TYR LEU LEU ARG LYS HIS GLU VAL SER
SEQRES 11 D 758 ARG LEU ASP VAL VAL ASN PHE ILE SER HIS GLY THR ARG
SEQRES 12 D 758 LYS ASP GLU PRO THR GLN SER SER ASP PRO GLY SER GLN
SEQRES 13 D 758 PRO ASN SER GLU GLU GLN ALA GLY GLY GLU GLU ARG MET
SEQRES 14 D 758 GLU ASN PHE THR THR ASN LEU ASN GLN LEU ALA ARG VAL
SEQRES 15 D 758 GLY GLY ILE ASP PRO LEU ILE GLY ARG GLU LYS GLU LEU
SEQRES 16 D 758 GLU ARG ALA ILE GLN VAL LEU CYS ARG ARG ARG LYS ASN
SEQRES 17 D 758 ASN PRO LEU LEU VAL GLY GLU SER GLY VAL GLY LYS THR
SEQRES 18 D 758 ALA ILE ALA GLU GLY LEU ALA TRP ARG ILE VAL GLN GLY
SEQRES 19 D 758 ASP VAL PRO GLU VAL MET ALA ASP CYS THR ILE TYR SER
SEQRES 20 D 758 LEU ASP ILE GLY SER LEU LEU ALA GLY THR LYS TYR ARG
SEQRES 21 D 758 GLY ASP PHE GLU LYS ARG PHE LYS ALA LEU LEU LYS GLN
SEQRES 22 D 758 LEU GLU GLN ASP THR ASN SER ILE LEU PHE ILE ASP GLU
SEQRES 23 D 758 ILE HIS THR ILE ILE GLY ALA GLY ALA ALA SER GLY GLY
SEQRES 24 D 758 GLN VAL ASP ALA ALA ASN LEU ILE LYS PRO LEU LEU SER
SEQRES 25 D 758 SER GLY LYS ILE ARG VAL ILE GLY SER THR THR TYR GLN
SEQRES 26 D 758 GLU PHE SER ASN ILE PHE GLU LYS ASP ARG ALA LEU ALA
SEQRES 27 D 758 ARG ARG PHE GLN LYS ILE ASP ILE THR GLU PRO SER ILE
SEQRES 28 D 758 GLU GLU THR VAL GLN ILE ILE ASN GLY LEU LYS PRO LYS
SEQRES 29 D 758 TYR GLU ALA HIS HIS ASP VAL ARG TYR THR ALA LYS ALA
SEQRES 30 D 758 VAL ARG ALA ALA VAL GLU LEU ALA VAL LYS TYR ILE ASN
SEQRES 31 D 758 ASP ARG HIS LEU PRO ASP LYS ALA ILE ASP VAL ILE ASP
SEQRES 32 D 758 GLU ALA GLY ALA ARG ALA ARG LEU MET PRO VAL SER LYS
SEQRES 33 D 758 ARG LYS LYS THR VAL ASN VAL ALA ASP ILE GLU SER VAL
SEQRES 34 D 758 VAL ALA ARG ILE ALA ARG ILE PRO GLU LYS SER VAL SER
SEQRES 35 D 758 GLN SER ASP ARG ASP THR LEU LYS ASN LEU GLY ASP ARG
SEQRES 36 D 758 LEU LYS MET LEU VAL PHE GLY GLN ASP LYS ALA ILE GLU
SEQRES 37 D 758 ALA LEU THR GLU ALA ILE LYS MET ALA ARG ALA GLY LEU
SEQRES 38 D 758 GLY HIS GLU HIS LYS PRO VAL GLY SER PHE LEU PHE ALA
SEQRES 39 D 758 GLY PRO THR GLY VAL GLY LYS THR GLU VAL THR VAL GLN
SEQRES 40 D 758 LEU SER LYS ALA LEU GLY ILE GLU LEU LEU ARG PHE ASP
SEQRES 41 D 758 MET SER GLU TYR MET GLU ARG HIS THR VAL SER ARG LEU
SEQRES 42 D 758 ILE GLY ALA PRO PRO GLY TYR VAL GLY PHE ASP GLN GLY
SEQRES 43 D 758 GLY LEU LEU THR ASP ALA VAL ILE LYS HIS PRO HIS ALA
SEQRES 44 D 758 VAL LEU LEU LEU ASP GLU ILE GLU LYS ALA HIS PRO ASP
SEQRES 45 D 758 VAL PHE ASN ILE LEU LEU GLN VAL MET ASP ASN GLY THR
SEQRES 46 D 758 LEU THR ASP ASN ASN GLY ARG LYS ALA ASP PHE ARG ASN
SEQRES 47 D 758 VAL VAL LEU VAL MET THR THR ASN ALA GLY VAL ARG GLU
SEQRES 48 D 758 THR GLU ARG LYS SER ILE GLY LEU ILE HIS GLN ASP ASN
SEQRES 49 D 758 SER THR ASP ALA MET GLU GLU ILE LYS LYS ILE PHE THR
SEQRES 50 D 758 PRO GLU PHE ARG ASN ARG LEU ASP ASN ILE ILE TRP PHE
SEQRES 51 D 758 ASP HIS LEU SER THR ASP VAL ILE HIS GLN VAL VAL ASP
SEQRES 52 D 758 LYS PHE ILE VAL GLU LEU GLN VAL GLN LEU ASP GLN LYS
SEQRES 53 D 758 GLY VAL SER LEU GLU VAL SER GLN GLU ALA ARG ASN TRP
SEQRES 54 D 758 LEU ALA GLU LYS GLY TYR ASP ARG ALA MET GLY ALA ARG
SEQRES 55 D 758 PRO MET ALA ARG VAL ILE GLN ASP ASN LEU LYS LYS PRO
SEQRES 56 D 758 LEU ALA ASN GLU LEU LEU PHE GLY SER LEU VAL ASP GLY
SEQRES 57 D 758 GLY GLN VAL THR VAL ALA LEU ASP LYS GLU LYS ASN GLU
SEQRES 58 D 758 LEU THR TYR GLY PHE GLN SER ALA GLN LYS HIS LYS ALA
SEQRES 59 D 758 GLU ALA ALA HIS
SEQRES 1 E 758 MET LEU ASN GLN GLU LEU GLU LEU SER LEU ASN MET ALA
SEQRES 2 E 758 PHE ALA ARG ALA ARG GLU HIS ARG HIS GLU PHE MET THR
SEQRES 3 E 758 VAL GLU HIS LEU LEU LEU ALA LEU LEU SER ASN PRO SER
SEQRES 4 E 758 ALA ARG GLU ALA LEU GLU ALA CYS SER VAL ASP LEU VAL
SEQRES 5 E 758 ALA LEU ARG GLN GLU LEU GLU ALA PHE ILE GLU GLN THR
SEQRES 6 E 758 THR PRO VAL LEU PRO ALA SER GLU GLU GLU ARG ASP THR
SEQRES 7 E 758 GLN PRO THR LEU SER PHE GLN ARG VAL LEU GLN ARG ALA
SEQRES 8 E 758 VAL PHE HIS VAL GLN SER SER GLY ARG ASN GLU VAL THR
SEQRES 9 E 758 GLY ALA ASN VAL LEU VAL ALA ILE PHE SER GLU GLN GLU
SEQRES 10 E 758 SER GLN ALA ALA TYR LEU LEU ARG LYS HIS GLU VAL SER
SEQRES 11 E 758 ARG LEU ASP VAL VAL ASN PHE ILE SER HIS GLY THR ARG
SEQRES 12 E 758 LYS ASP GLU PRO THR GLN SER SER ASP PRO GLY SER GLN
SEQRES 13 E 758 PRO ASN SER GLU GLU GLN ALA GLY GLY GLU GLU ARG MET
SEQRES 14 E 758 GLU ASN PHE THR THR ASN LEU ASN GLN LEU ALA ARG VAL
SEQRES 15 E 758 GLY GLY ILE ASP PRO LEU ILE GLY ARG GLU LYS GLU LEU
SEQRES 16 E 758 GLU ARG ALA ILE GLN VAL LEU CYS ARG ARG ARG LYS ASN
SEQRES 17 E 758 ASN PRO LEU LEU VAL GLY GLU SER GLY VAL GLY LYS THR
SEQRES 18 E 758 ALA ILE ALA GLU GLY LEU ALA TRP ARG ILE VAL GLN GLY
SEQRES 19 E 758 ASP VAL PRO GLU VAL MET ALA ASP CYS THR ILE TYR SER
SEQRES 20 E 758 LEU ASP ILE GLY SER LEU LEU ALA GLY THR LYS TYR ARG
SEQRES 21 E 758 GLY ASP PHE GLU LYS ARG PHE LYS ALA LEU LEU LYS GLN
SEQRES 22 E 758 LEU GLU GLN ASP THR ASN SER ILE LEU PHE ILE ASP GLU
SEQRES 23 E 758 ILE HIS THR ILE ILE GLY ALA GLY ALA ALA SER GLY GLY
SEQRES 24 E 758 GLN VAL ASP ALA ALA ASN LEU ILE LYS PRO LEU LEU SER
SEQRES 25 E 758 SER GLY LYS ILE ARG VAL ILE GLY SER THR THR TYR GLN
SEQRES 26 E 758 GLU PHE SER ASN ILE PHE GLU LYS ASP ARG ALA LEU ALA
SEQRES 27 E 758 ARG ARG PHE GLN LYS ILE ASP ILE THR GLU PRO SER ILE
SEQRES 28 E 758 GLU GLU THR VAL GLN ILE ILE ASN GLY LEU LYS PRO LYS
SEQRES 29 E 758 TYR GLU ALA HIS HIS ASP VAL ARG TYR THR ALA LYS ALA
SEQRES 30 E 758 VAL ARG ALA ALA VAL GLU LEU ALA VAL LYS TYR ILE ASN
SEQRES 31 E 758 ASP ARG HIS LEU PRO ASP LYS ALA ILE ASP VAL ILE ASP
SEQRES 32 E 758 GLU ALA GLY ALA ARG ALA ARG LEU MET PRO VAL SER LYS
SEQRES 33 E 758 ARG LYS LYS THR VAL ASN VAL ALA ASP ILE GLU SER VAL
SEQRES 34 E 758 VAL ALA ARG ILE ALA ARG ILE PRO GLU LYS SER VAL SER
SEQRES 35 E 758 GLN SER ASP ARG ASP THR LEU LYS ASN LEU GLY ASP ARG
SEQRES 36 E 758 LEU LYS MET LEU VAL PHE GLY GLN ASP LYS ALA ILE GLU
SEQRES 37 E 758 ALA LEU THR GLU ALA ILE LYS MET ALA ARG ALA GLY LEU
SEQRES 38 E 758 GLY HIS GLU HIS LYS PRO VAL GLY SER PHE LEU PHE ALA
SEQRES 39 E 758 GLY PRO THR GLY VAL GLY LYS THR GLU VAL THR VAL GLN
SEQRES 40 E 758 LEU SER LYS ALA LEU GLY ILE GLU LEU LEU ARG PHE ASP
SEQRES 41 E 758 MET SER GLU TYR MET GLU ARG HIS THR VAL SER ARG LEU
SEQRES 42 E 758 ILE GLY ALA PRO PRO GLY TYR VAL GLY PHE ASP GLN GLY
SEQRES 43 E 758 GLY LEU LEU THR ASP ALA VAL ILE LYS HIS PRO HIS ALA
SEQRES 44 E 758 VAL LEU LEU LEU ASP GLU ILE GLU LYS ALA HIS PRO ASP
SEQRES 45 E 758 VAL PHE ASN ILE LEU LEU GLN VAL MET ASP ASN GLY THR
SEQRES 46 E 758 LEU THR ASP ASN ASN GLY ARG LYS ALA ASP PHE ARG ASN
SEQRES 47 E 758 VAL VAL LEU VAL MET THR THR ASN ALA GLY VAL ARG GLU
SEQRES 48 E 758 THR GLU ARG LYS SER ILE GLY LEU ILE HIS GLN ASP ASN
SEQRES 49 E 758 SER THR ASP ALA MET GLU GLU ILE LYS LYS ILE PHE THR
SEQRES 50 E 758 PRO GLU PHE ARG ASN ARG LEU ASP ASN ILE ILE TRP PHE
SEQRES 51 E 758 ASP HIS LEU SER THR ASP VAL ILE HIS GLN VAL VAL ASP
SEQRES 52 E 758 LYS PHE ILE VAL GLU LEU GLN VAL GLN LEU ASP GLN LYS
SEQRES 53 E 758 GLY VAL SER LEU GLU VAL SER GLN GLU ALA ARG ASN TRP
SEQRES 54 E 758 LEU ALA GLU LYS GLY TYR ASP ARG ALA MET GLY ALA ARG
SEQRES 55 E 758 PRO MET ALA ARG VAL ILE GLN ASP ASN LEU LYS LYS PRO
SEQRES 56 E 758 LEU ALA ASN GLU LEU LEU PHE GLY SER LEU VAL ASP GLY
SEQRES 57 E 758 GLY GLN VAL THR VAL ALA LEU ASP LYS GLU LYS ASN GLU
SEQRES 58 E 758 LEU THR TYR GLY PHE GLN SER ALA GLN LYS HIS LYS ALA
SEQRES 59 E 758 GLU ALA ALA HIS
SEQRES 1 F 758 MET LEU ASN GLN GLU LEU GLU LEU SER LEU ASN MET ALA
SEQRES 2 F 758 PHE ALA ARG ALA ARG GLU HIS ARG HIS GLU PHE MET THR
SEQRES 3 F 758 VAL GLU HIS LEU LEU LEU ALA LEU LEU SER ASN PRO SER
SEQRES 4 F 758 ALA ARG GLU ALA LEU GLU ALA CYS SER VAL ASP LEU VAL
SEQRES 5 F 758 ALA LEU ARG GLN GLU LEU GLU ALA PHE ILE GLU GLN THR
SEQRES 6 F 758 THR PRO VAL LEU PRO ALA SER GLU GLU GLU ARG ASP THR
SEQRES 7 F 758 GLN PRO THR LEU SER PHE GLN ARG VAL LEU GLN ARG ALA
SEQRES 8 F 758 VAL PHE HIS VAL GLN SER SER GLY ARG ASN GLU VAL THR
SEQRES 9 F 758 GLY ALA ASN VAL LEU VAL ALA ILE PHE SER GLU GLN GLU
SEQRES 10 F 758 SER GLN ALA ALA TYR LEU LEU ARG LYS HIS GLU VAL SER
SEQRES 11 F 758 ARG LEU ASP VAL VAL ASN PHE ILE SER HIS GLY THR ARG
SEQRES 12 F 758 LYS ASP GLU PRO THR GLN SER SER ASP PRO GLY SER GLN
SEQRES 13 F 758 PRO ASN SER GLU GLU GLN ALA GLY GLY GLU GLU ARG MET
SEQRES 14 F 758 GLU ASN PHE THR THR ASN LEU ASN GLN LEU ALA ARG VAL
SEQRES 15 F 758 GLY GLY ILE ASP PRO LEU ILE GLY ARG GLU LYS GLU LEU
SEQRES 16 F 758 GLU ARG ALA ILE GLN VAL LEU CYS ARG ARG ARG LYS ASN
SEQRES 17 F 758 ASN PRO LEU LEU VAL GLY GLU SER GLY VAL GLY LYS THR
SEQRES 18 F 758 ALA ILE ALA GLU GLY LEU ALA TRP ARG ILE VAL GLN GLY
SEQRES 19 F 758 ASP VAL PRO GLU VAL MET ALA ASP CYS THR ILE TYR SER
SEQRES 20 F 758 LEU ASP ILE GLY SER LEU LEU ALA GLY THR LYS TYR ARG
SEQRES 21 F 758 GLY ASP PHE GLU LYS ARG PHE LYS ALA LEU LEU LYS GLN
SEQRES 22 F 758 LEU GLU GLN ASP THR ASN SER ILE LEU PHE ILE ASP GLU
SEQRES 23 F 758 ILE HIS THR ILE ILE GLY ALA GLY ALA ALA SER GLY GLY
SEQRES 24 F 758 GLN VAL ASP ALA ALA ASN LEU ILE LYS PRO LEU LEU SER
SEQRES 25 F 758 SER GLY LYS ILE ARG VAL ILE GLY SER THR THR TYR GLN
SEQRES 26 F 758 GLU PHE SER ASN ILE PHE GLU LYS ASP ARG ALA LEU ALA
SEQRES 27 F 758 ARG ARG PHE GLN LYS ILE ASP ILE THR GLU PRO SER ILE
SEQRES 28 F 758 GLU GLU THR VAL GLN ILE ILE ASN GLY LEU LYS PRO LYS
SEQRES 29 F 758 TYR GLU ALA HIS HIS ASP VAL ARG TYR THR ALA LYS ALA
SEQRES 30 F 758 VAL ARG ALA ALA VAL GLU LEU ALA VAL LYS TYR ILE ASN
SEQRES 31 F 758 ASP ARG HIS LEU PRO ASP LYS ALA ILE ASP VAL ILE ASP
SEQRES 32 F 758 GLU ALA GLY ALA ARG ALA ARG LEU MET PRO VAL SER LYS
SEQRES 33 F 758 ARG LYS LYS THR VAL ASN VAL ALA ASP ILE GLU SER VAL
SEQRES 34 F 758 VAL ALA ARG ILE ALA ARG ILE PRO GLU LYS SER VAL SER
SEQRES 35 F 758 GLN SER ASP ARG ASP THR LEU LYS ASN LEU GLY ASP ARG
SEQRES 36 F 758 LEU LYS MET LEU VAL PHE GLY GLN ASP LYS ALA ILE GLU
SEQRES 37 F 758 ALA LEU THR GLU ALA ILE LYS MET ALA ARG ALA GLY LEU
SEQRES 38 F 758 GLY HIS GLU HIS LYS PRO VAL GLY SER PHE LEU PHE ALA
SEQRES 39 F 758 GLY PRO THR GLY VAL GLY LYS THR GLU VAL THR VAL GLN
SEQRES 40 F 758 LEU SER LYS ALA LEU GLY ILE GLU LEU LEU ARG PHE ASP
SEQRES 41 F 758 MET SER GLU TYR MET GLU ARG HIS THR VAL SER ARG LEU
SEQRES 42 F 758 ILE GLY ALA PRO PRO GLY TYR VAL GLY PHE ASP GLN GLY
SEQRES 43 F 758 GLY LEU LEU THR ASP ALA VAL ILE LYS HIS PRO HIS ALA
SEQRES 44 F 758 VAL LEU LEU LEU ASP GLU ILE GLU LYS ALA HIS PRO ASP
SEQRES 45 F 758 VAL PHE ASN ILE LEU LEU GLN VAL MET ASP ASN GLY THR
SEQRES 46 F 758 LEU THR ASP ASN ASN GLY ARG LYS ALA ASP PHE ARG ASN
SEQRES 47 F 758 VAL VAL LEU VAL MET THR THR ASN ALA GLY VAL ARG GLU
SEQRES 48 F 758 THR GLU ARG LYS SER ILE GLY LEU ILE HIS GLN ASP ASN
SEQRES 49 F 758 SER THR ASP ALA MET GLU GLU ILE LYS LYS ILE PHE THR
SEQRES 50 F 758 PRO GLU PHE ARG ASN ARG LEU ASP ASN ILE ILE TRP PHE
SEQRES 51 F 758 ASP HIS LEU SER THR ASP VAL ILE HIS GLN VAL VAL ASP
SEQRES 52 F 758 LYS PHE ILE VAL GLU LEU GLN VAL GLN LEU ASP GLN LYS
SEQRES 53 F 758 GLY VAL SER LEU GLU VAL SER GLN GLU ALA ARG ASN TRP
SEQRES 54 F 758 LEU ALA GLU LYS GLY TYR ASP ARG ALA MET GLY ALA ARG
SEQRES 55 F 758 PRO MET ALA ARG VAL ILE GLN ASP ASN LEU LYS LYS PRO
SEQRES 56 F 758 LEU ALA ASN GLU LEU LEU PHE GLY SER LEU VAL ASP GLY
SEQRES 57 F 758 GLY GLN VAL THR VAL ALA LEU ASP LYS GLU LYS ASN GLU
SEQRES 58 F 758 LEU THR TYR GLY PHE GLN SER ALA GLN LYS HIS LYS ALA
SEQRES 59 F 758 GLU ALA ALA HIS
SEQRES 1 X 24 UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES 2 X 24 UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
HET ATP A 801 31
HET ADP A 802 27
HET ATP B 801 31
HET ATP B 802 31
HET ATP C 801 31
HET ATP C 802 31
HET ATP D 801 31
HET ATP D 802 31
HET ADP E 801 27
HET ATP E 802 31
HET ADP F 801 27
HET ADP F 802 27
HETNAM ATP ADENOSINE-5'-TRIPHOSPHATE
HETNAM ADP ADENOSINE-5'-DIPHOSPHATE
FORMUL 22 ATP 8(C10 H16 N5 O13 P3)
FORMUL 23 ADP 4(C10 H15 N5 O10 P2)
HELIX 1 AA1 ILE G 33 LYS G 39 1 7
HELIX 2 AA2 GLU G 50 ASN G 68 1 19
HELIX 3 AA3 VAL G 83 ILE G 97 1 15
HELIX 4 AA4 SER G 111 THR G 118 1 8
HELIX 5 AA5 ALA G 146 GLY G 172 1 27
HELIX 6 AA6 SER G 174 THR G 182 1 9
HELIX 7 AA7 ALA G 190 GLY G 197 1 8
HELIX 8 AA8 ILE H 33 LYS H 39 1 7
HELIX 9 AA9 GLU H 50 ASN H 68 1 19
HELIX 10 AB1 VAL H 83 ILE H 97 1 15
HELIX 11 AB2 SER H 111 THR H 118 1 8
HELIX 12 AB3 ALA H 146 GLY H 172 1 27
HELIX 13 AB4 SER H 174 THR H 182 1 9
HELIX 14 AB5 ALA H 190 GLY H 197 1 8
HELIX 15 AB6 ILE I 33 LYS I 39 1 7
HELIX 16 AB7 GLU I 50 ASN I 68 1 19
HELIX 17 AB8 VAL I 83 ILE I 97 1 15
HELIX 18 AB9 SER I 111 THR I 118 1 8
HELIX 19 AC1 ALA I 146 GLY I 172 1 27
HELIX 20 AC2 SER I 174 THR I 182 1 9
HELIX 21 AC3 ALA I 190 GLY I 197 1 8
HELIX 22 AC4 ILE J 33 LYS J 39 1 7
HELIX 23 AC5 HIS J 52 ALA J 54 5 3
HELIX 24 AC6 ASN J 55 ASN J 68 1 14
HELIX 25 AC7 VAL J 83 ILE J 97 1 15
HELIX 26 AC8 SER J 111 THR J 118 1 8
HELIX 27 AC9 ALA J 146 GLY J 172 1 27
HELIX 28 AD1 SER J 174 ASP J 181 1 8
HELIX 29 AD2 ALA J 190 GLY J 197 1 8
HELIX 30 AD3 ILE K 33 LYS K 39 1 7
HELIX 31 AD4 GLU K 50 ASN K 68 1 19
HELIX 32 AD5 VAL K 83 ILE K 97 1 15
HELIX 33 AD6 SER K 111 THR K 118 1 8
HELIX 34 AD7 ALA K 146 GLY K 172 1 27
HELIX 35 AD8 SER K 174 THR K 182 1 9
HELIX 36 AD9 ALA K 190 GLY K 197 1 8
HELIX 37 AE1 ILE L 33 LYS L 39 1 7
HELIX 38 AE2 GLU L 50 ASN L 68 1 19
HELIX 39 AE3 VAL L 83 ILE L 97 1 15
HELIX 40 AE4 SER L 111 THR L 118 1 8
HELIX 41 AE5 ALA L 146 GLY L 172 1 27
HELIX 42 AE6 SER L 174 THR L 182 1 9
HELIX 43 AE7 ALA L 190 GLY L 197 1 8
HELIX 44 AE8 ILE M 33 LYS M 39 1 7
HELIX 45 AE9 GLU M 50 ASN M 68 1 19
HELIX 46 AF1 VAL M 83 ILE M 97 1 15
HELIX 47 AF2 SER M 111 THR M 118 1 8
HELIX 48 AF3 ALA M 146 GLY M 172 1 27
HELIX 49 AF4 SER M 174 THR M 182 1 9
HELIX 50 AF5 ALA M 190 GLY M 197 1 8
HELIX 51 AF6 ILE N 33 LYS N 39 1 7
HELIX 52 AF7 GLU N 50 ASN N 68 1 19
HELIX 53 AF8 ILE N 84 GLN N 95 1 12
HELIX 54 AF9 SER N 111 ALA N 119 1 9
HELIX 55 AG1 ALA N 146 GLY N 172 1 27
HELIX 56 AG2 SER N 174 THR N 182 1 9
HELIX 57 AG3 ALA N 190 GLY N 197 1 8
HELIX 58 AG4 ILE O 33 LYS O 39 1 7
HELIX 59 AG5 GLU O 50 ASN O 68 1 19
HELIX 60 AG6 VAL O 83 ILE O 97 1 15
HELIX 61 AG7 SER O 111 ALA O 119 1 9
HELIX 62 AG8 ALA O 146 GLY O 172 1 27
HELIX 63 AG9 SER O 174 THR O 182 1 9
HELIX 64 AH1 ALA O 190 GLY O 197 1 8
HELIX 65 AH2 ILE P 33 LYS P 39 1 7
HELIX 66 AH3 GLU P 50 ASN P 68 1 19
HELIX 67 AH4 VAL P 83 ILE P 97 1 15
HELIX 68 AH5 SER P 111 ALA P 119 1 9
HELIX 69 AH6 ALA P 146 GLY P 172 1 27
HELIX 70 AH7 SER P 174 GLU P 183 1 10
HELIX 71 AH8 ALA P 190 GLY P 197 1 8
HELIX 72 AH9 ILE Q 33 LYS Q 39 1 7
HELIX 73 AI1 GLU Q 50 ASN Q 68 1 19
HELIX 74 AI2 ILE Q 84 ILE Q 97 1 14
HELIX 75 AI3 SER Q 111 ALA Q 119 1 9
HELIX 76 AI4 ALA Q 146 GLY Q 172 1 27
HELIX 77 AI5 SER Q 174 THR Q 182 1 9
HELIX 78 AI6 SER Q 189 GLY Q 197 1 9
HELIX 79 AI7 ILE R 33 LYS R 39 1 7
HELIX 80 AI8 GLU R 50 ASN R 68 1 19
HELIX 81 AI9 VAL R 83 ILE R 97 1 15
HELIX 82 AJ1 SER R 111 THR R 118 1 8
HELIX 83 AJ2 ALA R 146 GLY R 172 1 27
HELIX 84 AJ3 SER R 174 THR R 182 1 9
HELIX 85 AJ4 ALA R 190 GLY R 197 1 8
HELIX 86 AJ5 ILE S 33 LYS S 39 1 7
HELIX 87 AJ6 GLU S 50 ASN S 68 1 19
HELIX 88 AJ7 VAL S 83 ILE S 97 1 15
HELIX 89 AJ8 SER S 111 THR S 118 1 8
HELIX 90 AJ9 ALA S 146 GLY S 172 1 27
HELIX 91 AK1 SER S 174 THR S 182 1 9
HELIX 92 AK2 ALA S 190 GLY S 197 1 8
HELIX 93 AK3 ILE T 33 LYS T 39 1 7
HELIX 94 AK4 GLU T 50 ASN T 68 1 19
HELIX 95 AK5 VAL T 83 ILE T 97 1 15
HELIX 96 AK6 SER T 111 THR T 118 1 8
HELIX 97 AK7 ALA T 146 GLY T 172 1 27
HELIX 98 AK8 SER T 174 THR T 182 1 9
HELIX 99 AK9 ALA T 190 GLY T 197 1 8
HELIX 100 AL1 LEU A 176 GLY A 183 1 8
HELIX 101 AL2 GLU A 192 CYS A 203 1 12
HELIX 102 AL3 GLY A 219 GLN A 233 1 15
HELIX 103 AL4 PRO A 237 ALA A 241 5 5
HELIX 104 AL5 ASP A 249 ALA A 255 1 7
HELIX 105 AL6 GLY A 261 GLN A 276 1 16
HELIX 106 AL7 GLU A 286 ILE A 290 5 5
HELIX 107 AL8 ASP A 302 SER A 312 1 11
HELIX 108 AL9 TYR A 324 PHE A 331 1 8
HELIX 109 AM1 ASP A 334 ARG A 339 1 6
HELIX 110 AM2 SER A 350 LYS A 362 1 13
HELIX 111 AM3 LYS A 362 ASP A 370 1 9
HELIX 112 AM4 THR A 374 ILE A 389 1 16
HELIX 113 AM5 HIS A 393 ARG A 410 1 18
HELIX 114 AM6 LEU A 411 LYS A 416 5 6
HELIX 115 AM7 ASN A 422 ALA A 434 1 13
HELIX 116 AM8 ASP A 445 LYS A 450 1 6
HELIX 117 AM9 ASN A 451 MET A 458 1 8
HELIX 118 AN1 GLN A 463 ALA A 479 1 17
HELIX 119 AN2 GLY A 500 GLY A 513 1 14
HELIX 120 AN3 SER A 522 TYR A 524 5 3
HELIX 121 AN4 GLU A 526 THR A 529 5 4
HELIX 122 AN5 VAL A 530 GLY A 535 1 6
HELIX 123 AN6 GLY A 547 HIS A 556 1 10
HELIX 124 AN7 GLU A 565 ALA A 569 5 5
HELIX 125 AN8 HIS A 570 GLY A 584 1 15
HELIX 126 AN9 VAL A 609 GLU A 613 5 5
HELIX 127 AO1 THR A 626 LYS A 634 1 9
HELIX 128 AO2 THR A 637 ASN A 642 1 6
HELIX 129 AO3 SER A 654 GLN A 675 1 22
HELIX 130 AO4 SER A 683 TYR A 695 1 13
HELIX 131 AO5 PRO A 703 LYS A 713 1 11
HELIX 132 AO6 LEU A 716 PHE A 722 1 7
HELIX 133 AO7 LEU B 176 ARG B 181 1 6
HELIX 134 AO8 ARG B 191 CYS B 203 1 13
HELIX 135 AO9 GLY B 219 GLY B 234 1 16
HELIX 136 AP1 ASP B 249 ALA B 255 1 7
HELIX 137 AP2 GLY B 261 GLN B 276 1 16
HELIX 138 AP3 GLU B 286 ALA B 293 5 8
HELIX 139 AP4 ILE B 307 SER B 313 1 7
HELIX 140 AP5 TYR B 324 ILE B 330 1 7
HELIX 141 AP6 ASP B 334 ARG B 339 1 6
HELIX 142 AP7 SER B 350 ASP B 370 1 21
HELIX 143 AP8 THR B 374 ILE B 389 1 16
HELIX 144 AP9 HIS B 393 ARG B 410 1 18
HELIX 145 AQ1 ASN B 422 ARG B 435 1 14
HELIX 146 AQ2 LYS B 439 GLN B 443 5 5
HELIX 147 AQ3 SER B 444 ASN B 451 1 8
HELIX 148 AQ4 ASN B 451 MET B 458 1 8
HELIX 149 AQ5 GLN B 463 GLY B 480 1 18
HELIX 150 AQ6 THR B 502 GLY B 513 1 12
HELIX 151 AQ7 SER B 522 TYR B 524 5 3
HELIX 152 AQ8 GLU B 526 THR B 529 5 4
HELIX 153 AQ9 VAL B 530 GLY B 535 1 6
HELIX 154 AR1 GLY B 542 GLY B 546 5 5
HELIX 155 AR2 GLY B 547 HIS B 556 1 10
HELIX 156 AR3 GLU B 565 ALA B 569 5 5
HELIX 157 AR4 HIS B 570 VAL B 573 5 4
HELIX 158 AR5 PHE B 574 GLY B 584 1 11
HELIX 159 AR6 VAL B 609 GLU B 613 5 5
HELIX 160 AR7 THR B 626 PHE B 636 1 11
HELIX 161 AR8 THR B 637 ASN B 642 1 6
HELIX 162 AR9 SER B 654 GLN B 675 1 22
HELIX 163 AS1 SER B 683 TYR B 695 1 13
HELIX 164 AS2 ASP B 696 GLY B 700 5 5
HELIX 165 AS3 ALA B 701 ARG B 702 5 2
HELIX 166 AS4 PRO B 703 LEU B 712 1 10
HELIX 167 AS5 LEU B 712 PHE B 722 1 11
HELIX 168 AS6 LEU C 176 GLY C 183 1 8
HELIX 169 AS7 ARG C 191 CYS C 203 1 13
HELIX 170 AS8 GLY C 219 GLN C 233 1 15
HELIX 171 AS9 GLY C 251 GLY C 256 1 6
HELIX 172 AT1 GLY C 261 THR C 278 1 18
HELIX 173 AT2 GLU C 286 ILE C 290 5 5
HELIX 174 AT3 ILE C 307 SER C 313 1 7
HELIX 175 AT4 TYR C 324 ILE C 330 1 7
HELIX 176 AT5 ASP C 334 ARG C 339 1 6
HELIX 177 AT6 SER C 350 ASP C 370 1 21
HELIX 178 AT7 THR C 374 ILE C 389 1 16
HELIX 179 AT8 HIS C 393 ARG C 410 1 18
HELIX 180 AT9 LEU C 411 LYS C 416 5 6
HELIX 181 AU1 ASN C 422 ARG C 435 1 14
HELIX 182 AU2 LYS C 439 GLN C 443 5 5
HELIX 183 AU3 SER C 444 ASN C 451 1 8
HELIX 184 AU4 ASN C 451 LEU C 456 1 6
HELIX 185 AU5 LYS C 457 LEU C 459 5 3
HELIX 186 AU6 GLN C 463 GLY C 480 1 18
HELIX 187 AU7 THR C 502 GLY C 513 1 12
HELIX 188 AU8 SER C 522 TYR C 524 5 3
HELIX 189 AU9 GLU C 526 THR C 529 5 4
HELIX 190 AV1 VAL C 530 GLY C 535 1 6
HELIX 191 AV2 TYR C 540 ASP C 544 5 5
HELIX 192 AV3 GLY C 547 HIS C 556 1 10
HELIX 193 AV4 GLU C 565 ALA C 569 5 5
HELIX 194 AV5 HIS C 570 ILE C 576 5 7
HELIX 195 AV6 LEU C 577 GLY C 584 1 8
HELIX 196 AV7 GLY C 608 GLU C 613 1 6
HELIX 197 AV8 GLU C 630 PHE C 636 1 7
HELIX 198 AV9 THR C 637 ASN C 642 1 6
HELIX 199 AW1 SER C 654 GLN C 675 1 22
HELIX 200 AW2 SER C 683 TYR C 695 1 13
HELIX 201 AW3 ASP C 696 GLY C 700 5 5
HELIX 202 AW4 PRO C 703 LEU C 712 1 10
HELIX 203 AW5 LEU C 712 PHE C 722 1 11
HELIX 204 AW6 LEU D 176 VAL D 182 1 7
HELIX 205 AW7 ARG D 191 CYS D 203 1 13
HELIX 206 AW8 GLY D 219 GLY D 234 1 16
HELIX 207 AW9 PRO D 237 ALA D 241 5 5
HELIX 208 AX1 ASP D 249 ALA D 255 1 7
HELIX 209 AX2 GLY D 261 THR D 278 1 18
HELIX 210 AX3 GLU D 286 ILE D 290 5 5
HELIX 211 AX4 ASP D 302 ILE D 307 1 6
HELIX 212 AX5 ILE D 307 GLY D 314 1 8
HELIX 213 AX6 TYR D 324 ILE D 330 1 7
HELIX 214 AX7 PHE D 331 LYS D 333 5 3
HELIX 215 AX8 ASP D 334 ARG D 339 1 6
HELIX 216 AX9 SER D 350 ASP D 370 1 21
HELIX 217 AY1 THR D 374 ILE D 389 1 16
HELIX 218 AY2 HIS D 393 LEU D 411 1 19
HELIX 219 AY3 ASN D 422 ALA D 434 1 13
HELIX 220 AY4 GLN D 443 ASN D 451 1 9
HELIX 221 AY5 ASN D 451 LYS D 457 1 7
HELIX 222 AY6 GLN D 463 GLY D 480 1 18
HELIX 223 AY7 GLY D 500 GLY D 513 1 14
HELIX 224 AY8 SER D 522 TYR D 524 5 3
HELIX 225 AY9 GLU D 526 HIS D 528 5 3
HELIX 226 AZ1 THR D 529 GLY D 535 1 7
HELIX 227 AZ2 GLY D 547 HIS D 556 1 10
HELIX 228 AZ3 GLU D 565 HIS D 570 5 6
HELIX 229 AZ4 PRO D 571 GLY D 584 1 14
HELIX 230 AZ5 GLY D 608 GLU D 613 1 6
HELIX 231 AZ6 ASN D 624 PHE D 636 1 13
HELIX 232 AZ7 THR D 637 ASN D 642 1 6
HELIX 233 AZ8 SER D 654 GLN D 675 1 22
HELIX 234 AZ9 SER D 683 TYR D 695 1 13
HELIX 235 BA1 PRO D 703 LEU D 712 1 10
HELIX 236 BA2 LEU D 712 GLY D 723 1 12
HELIX 237 BA3 LEU E 176 GLY E 183 1 8
HELIX 238 BA4 ARG E 191 CYS E 203 1 13
HELIX 239 BA5 GLY E 219 GLY E 234 1 16
HELIX 240 BA6 SER E 252 GLY E 256 5 5
HELIX 241 BA7 TYR E 259 ASP E 277 1 19
HELIX 242 BA8 GLU E 286 ILE E 290 5 5
HELIX 243 BA9 GLY E 299 SER E 313 1 15
HELIX 244 BB1 TYR E 324 PHE E 331 1 8
HELIX 245 BB2 ASP E 334 ARG E 339 1 6
HELIX 246 BB3 SER E 350 ASP E 370 1 21
HELIX 247 BB4 THR E 374 ILE E 389 1 16
HELIX 248 BB5 HIS E 393 MET E 412 1 20
HELIX 249 BB6 ASN E 422 ALA E 434 1 13
HELIX 250 BB7 ASP E 445 ASN E 451 1 7
HELIX 251 BB8 ASN E 451 MET E 458 1 8
HELIX 252 BB9 GLN E 463 ALA E 479 1 17
HELIX 253 BC1 THR E 502 GLY E 513 1 12
HELIX 254 BC2 SER E 522 MET E 525 5 4
HELIX 255 BC3 THR E 529 ILE E 534 1 6
HELIX 256 BC4 GLY E 547 HIS E 556 1 10
HELIX 257 BC5 GLU E 565 ALA E 569 5 5
HELIX 258 BC6 HIS E 570 PRO E 571 5 2
HELIX 259 BC7 ASP E 572 GLY E 584 1 13
HELIX 260 BC8 ASN E 606 ARG E 610 5 5
HELIX 261 BC9 MET E 629 LYS E 634 1 6
HELIX 262 BD1 THR E 637 ASN E 642 1 6
HELIX 263 BD2 SER E 654 GLN E 675 1 22
HELIX 264 BD3 SER E 683 GLY E 694 1 12
HELIX 265 BD4 ASP E 696 GLY E 700 5 5
HELIX 266 BD5 ALA E 701 LEU E 712 1 12
HELIX 267 BD6 LEU E 712 GLY E 723 1 12
HELIX 268 BD7 SER E 724 GLY E 728 5 5
HELIX 269 BD8 LEU F 176 VAL F 182 1 7
HELIX 270 BD9 ARG F 191 CYS F 203 1 13
HELIX 271 BE1 GLY F 219 GLN F 233 1 15
HELIX 272 BE2 PRO F 237 ALA F 241 5 5
HELIX 273 BE3 ASP F 249 ALA F 255 1 7
HELIX 274 BE4 TYR F 259 ASP F 277 1 19
HELIX 275 BE5 GLU F 286 ILE F 290 5 5
HELIX 276 BE6 ASP F 302 GLY F 314 1 13
HELIX 277 BE7 TYR F 324 PHE F 331 1 8
HELIX 278 BE8 ASP F 334 ARG F 339 1 6
HELIX 279 BE9 SER F 350 ASP F 370 1 21
HELIX 280 BF1 THR F 374 ILE F 389 1 16
HELIX 281 BF2 HIS F 393 MET F 412 1 20
HELIX 282 BF3 ASN F 422 ARG F 435 1 14
HELIX 283 BF4 ILE F 436 VAL F 441 1 6
HELIX 284 BF5 ARG F 446 LYS F 457 1 12
HELIX 285 BF6 GLN F 463 ALA F 479 1 17
HELIX 286 BF7 GLY F 500 GLY F 513 1 14
HELIX 287 BF8 SER F 522 MET F 525 5 4
HELIX 288 BF9 GLU F 526 GLY F 535 1 10
HELIX 289 BG1 GLY F 547 HIS F 556 1 10
HELIX 290 BG2 GLU F 565 ALA F 569 5 5
HELIX 291 BG3 HIS F 570 GLY F 584 1 15
HELIX 292 BG4 ASN F 606 GLU F 611 1 6
HELIX 293 BG5 THR F 612 ARG F 614 5 3
HELIX 294 BG6 ASP F 627 LYS F 634 1 8
HELIX 295 BG7 THR F 637 ASN F 642 1 6
HELIX 296 BG8 SER F 654 GLY F 677 1 24
HELIX 297 BG9 SER F 683 TYR F 695 1 13
HELIX 298 BH1 PRO F 703 LEU F 712 1 10
HELIX 299 BH2 LYS F 713 GLY F 723 1 11
SHEET 1 AA1 2 MET G 19 GLN G 23 0
SHEET 2 AA1 2 GLU G 28 ASP G 32 -1 O PHE G 31 N VAL G 20
SHEET 1 AA2 5 VAL G 42 THR G 46 0
SHEET 2 AA2 5 ILE G 73 SER G 79 1 O TYR G 76 N LEU G 45
SHEET 3 AA2 5 VAL G 101 ALA G 110 1 O SER G 102 N LEU G 75
SHEET 4 AA2 5 ARG G 132 ILE G 135 1 O ARG G 132 N ALA G 109
SHEET 5 AA2 5 ARG G 186 SER G 189 -1 O LEU G 188 N VAL G 133
SHEET 1 AA3 5 VAL G 42 THR G 46 0
SHEET 2 AA3 5 ILE G 73 SER G 79 1 O TYR G 76 N LEU G 45
SHEET 3 AA3 5 VAL G 101 ALA G 110 1 O SER G 102 N LEU G 75
SHEET 4 AA3 5 PHE G 126 CYS G 127 1 O PHE G 126 N CYS G 105
SHEET 5 AA3 5 SER G 201 ILE G 202 1 O SER G 201 N CYS G 127
SHEET 1 AA4 2 LEU G 139 GLN G 145 0
SHEET 2 AA4 2 LEU N 139 GLN N 145 -1 O GLY N 140 N GLY G 144
SHEET 1 AA5 2 MET H 19 VAL H 20 0
SHEET 2 AA5 2 PHE H 31 ASP H 32 -1 O PHE H 31 N VAL H 20
SHEET 1 AA6 5 VAL H 42 THR H 46 0
SHEET 2 AA6 5 ILE H 73 SER H 79 1 O TYR H 76 N LEU H 45
SHEET 3 AA6 5 VAL H 101 ALA H 110 1 O ILE H 104 N ILE H 77
SHEET 4 AA6 5 ARG H 132 ILE H 135 1 O ARG H 132 N ALA H 109
SHEET 5 AA6 5 ARG H 186 SER H 189 -1 O LEU H 188 N VAL H 133
SHEET 1 AA7 5 VAL H 42 THR H 46 0
SHEET 2 AA7 5 ILE H 73 SER H 79 1 O TYR H 76 N LEU H 45
SHEET 3 AA7 5 VAL H 101 ALA H 110 1 O ILE H 104 N ILE H 77
SHEET 4 AA7 5 PHE H 126 CYS H 127 1 O PHE H 126 N THR H 103
SHEET 5 AA7 5 SER H 201 ILE H 202 1 O SER H 201 N CYS H 127
SHEET 1 AA8 2 LEU H 139 GLN H 145 0
SHEET 2 AA8 2 LEU O 139 GLN O 145 -1 O GLY O 140 N GLY H 144
SHEET 1 AA9 2 MET I 19 ILE I 21 0
SHEET 2 AA9 2 SER I 30 ASP I 32 -1 O PHE I 31 N VAL I 20
SHEET 1 AB1 5 VAL I 42 THR I 46 0
SHEET 2 AB1 5 ILE I 73 SER I 79 1 O TYR I 76 N LEU I 45
SHEET 3 AB1 5 VAL I 101 ALA I 110 1 O SER I 102 N ILE I 73
SHEET 4 AB1 5 ARG I 132 ILE I 135 1 O ARG I 132 N ALA I 109
SHEET 5 AB1 5 ARG I 186 SER I 189 -1 O LEU I 188 N VAL I 133
SHEET 1 AB2 5 VAL I 42 THR I 46 0
SHEET 2 AB2 5 ILE I 73 SER I 79 1 O TYR I 76 N LEU I 45
SHEET 3 AB2 5 VAL I 101 ALA I 110 1 O SER I 102 N ILE I 73
SHEET 4 AB2 5 PHE I 126 CYS I 127 1 O PHE I 126 N CYS I 105
SHEET 5 AB2 5 SER I 201 ILE I 202 1 O SER I 201 N CYS I 127
SHEET 1 AB3 2 LEU I 139 GLN I 145 0
SHEET 2 AB3 2 LEU P 139 GLN P 145 -1 O GLY P 144 N GLY I 140
SHEET 1 AB4 2 MET J 19 ILE J 21 0
SHEET 2 AB4 2 SER J 30 ASP J 32 -1 O PHE J 31 N VAL J 20
SHEET 1 AB5 5 VAL J 42 THR J 46 0
SHEET 2 AB5 5 ILE J 73 SER J 79 1 O TYR J 76 N LEU J 45
SHEET 3 AB5 5 VAL J 101 ALA J 110 1 O SER J 102 N LEU J 75
SHEET 4 AB5 5 ARG J 132 ILE J 135 1 O ARG J 132 N ALA J 109
SHEET 5 AB5 5 ARG J 186 SER J 189 -1 O LEU J 188 N VAL J 133
SHEET 1 AB6 5 VAL J 42 THR J 46 0
SHEET 2 AB6 5 ILE J 73 SER J 79 1 O TYR J 76 N LEU J 45
SHEET 3 AB6 5 VAL J 101 ALA J 110 1 O SER J 102 N LEU J 75
SHEET 4 AB6 5 PHE J 126 CYS J 127 1 O PHE J 126 N CYS J 105
SHEET 5 AB6 5 SER J 201 ILE J 202 1 O SER J 201 N CYS J 127
SHEET 1 AB7 2 LEU J 139 GLN J 145 0
SHEET 2 AB7 2 LEU Q 139 GLN Q 145 -1 O GLY Q 144 N GLY J 140
SHEET 1 AB8 2 MET K 19 ILE K 21 0
SHEET 2 AB8 2 SER K 30 ASP K 32 -1 O PHE K 31 N VAL K 20
SHEET 1 AB9 5 VAL K 42 THR K 46 0
SHEET 2 AB9 5 ILE K 73 SER K 79 1 O TYR K 76 N LEU K 45
SHEET 3 AB9 5 VAL K 101 ALA K 110 1 O ILE K 104 N ILE K 77
SHEET 4 AB9 5 ARG K 132 ILE K 135 1 O MET K 134 N ALA K 109
SHEET 5 AB9 5 ARG K 186 SER K 189 -1 O LEU K 188 N VAL K 133
SHEET 1 AC1 5 VAL K 42 THR K 46 0
SHEET 2 AC1 5 ILE K 73 SER K 79 1 O TYR K 76 N LEU K 45
SHEET 3 AC1 5 VAL K 101 ALA K 110 1 O ILE K 104 N ILE K 77
SHEET 4 AC1 5 PHE K 126 CYS K 127 1 O PHE K 126 N CYS K 105
SHEET 5 AC1 5 SER K 201 ILE K 202 1 O SER K 201 N CYS K 127
SHEET 1 AC2 2 LEU K 139 GLN K 145 0
SHEET 2 AC2 2 LEU R 139 GLN R 145 -1 O GLY R 144 N GLY K 140
SHEET 1 AC3 5 VAL L 42 VAL L 49 0
SHEET 2 AC3 5 ILE L 73 GLY L 82 1 O TYR L 76 N LEU L 45
SHEET 3 AC3 5 VAL L 101 ALA L 110 1 O SER L 102 N LEU L 75
SHEET 4 AC3 5 ARG L 132 ILE L 135 1 O MET L 134 N ALA L 109
SHEET 5 AC3 5 ARG L 186 SER L 189 -1 O LEU L 188 N VAL L 133
SHEET 1 AC4 5 VAL L 42 VAL L 49 0
SHEET 2 AC4 5 ILE L 73 GLY L 82 1 O TYR L 76 N LEU L 45
SHEET 3 AC4 5 VAL L 101 ALA L 110 1 O SER L 102 N LEU L 75
SHEET 4 AC4 5 ARG L 125 CYS L 127 1 O PHE L 126 N THR L 103
SHEET 5 AC4 5 SER L 201 ILE L 202 1 O SER L 201 N CYS L 127
SHEET 1 AC5 2 LEU L 139 GLN L 145 0
SHEET 2 AC5 2 LEU S 139 GLN S 145 -1 O GLY S 140 N GLY L 144
SHEET 1 AC6 2 MET M 19 GLN M 23 0
SHEET 2 AC6 2 GLU M 28 ASP M 32 -1 O PHE M 31 N VAL M 20
SHEET 1 AC7 5 VAL M 42 THR M 46 0
SHEET 2 AC7 5 ILE M 73 SER M 79 1 O TYR M 76 N LEU M 45
SHEET 3 AC7 5 VAL M 101 ALA M 110 1 O SER M 102 N ILE M 73
SHEET 4 AC7 5 ARG M 132 ILE M 135 1 O ARG M 132 N ALA M 109
SHEET 5 AC7 5 ARG M 186 SER M 189 -1 O LEU M 188 N VAL M 133
SHEET 1 AC8 5 VAL M 42 THR M 46 0
SHEET 2 AC8 5 ILE M 73 SER M 79 1 O TYR M 76 N LEU M 45
SHEET 3 AC8 5 VAL M 101 ALA M 110 1 O SER M 102 N ILE M 73
SHEET 4 AC8 5 PHE M 126 CYS M 127 1 O PHE M 126 N CYS M 105
SHEET 5 AC8 5 SER M 201 ILE M 202 1 O SER M 201 N CYS M 127
SHEET 1 AC9 2 LEU M 139 GLN M 145 0
SHEET 2 AC9 2 LEU T 139 GLN T 145 -1 O GLY T 144 N GLY M 140
SHEET 1 AD1 2 MET N 19 ILE N 21 0
SHEET 2 AD1 2 SER N 30 ASP N 32 -1 O PHE N 31 N VAL N 20
SHEET 1 AD2 5 VAL N 42 THR N 46 0
SHEET 2 AD2 5 ILE N 73 SER N 79 1 O TYR N 76 N LEU N 45
SHEET 3 AD2 5 VAL N 101 ALA N 110 1 O ILE N 104 N ILE N 77
SHEET 4 AD2 5 ARG N 132 ILE N 135 1 O MET N 134 N ALA N 109
SHEET 5 AD2 5 ARG N 186 SER N 189 -1 O LEU N 188 N VAL N 133
SHEET 1 AD3 5 VAL N 42 THR N 46 0
SHEET 2 AD3 5 ILE N 73 SER N 79 1 O TYR N 76 N LEU N 45
SHEET 3 AD3 5 VAL N 101 ALA N 110 1 O ILE N 104 N ILE N 77
SHEET 4 AD3 5 PHE N 126 CYS N 127 1 O PHE N 126 N THR N 103
SHEET 5 AD3 5 SER N 201 ILE N 202 1 O SER N 201 N CYS N 127
SHEET 1 AD4 2 MET O 19 ILE O 21 0
SHEET 2 AD4 2 SER O 30 ASP O 32 -1 O PHE O 31 N VAL O 20
SHEET 1 AD5 5 VAL O 42 THR O 46 0
SHEET 2 AD5 5 ILE O 73 SER O 79 1 O TYR O 76 N LEU O 45
SHEET 3 AD5 5 VAL O 101 ALA O 110 1 O ILE O 104 N ILE O 77
SHEET 4 AD5 5 ARG O 132 ILE O 135 1 O MET O 134 N ALA O 109
SHEET 5 AD5 5 ARG O 186 SER O 189 -1 O LEU O 188 N VAL O 133
SHEET 1 AD6 5 VAL O 42 THR O 46 0
SHEET 2 AD6 5 ILE O 73 SER O 79 1 O TYR O 76 N LEU O 45
SHEET 3 AD6 5 VAL O 101 ALA O 110 1 O ILE O 104 N ILE O 77
SHEET 4 AD6 5 ARG O 125 CYS O 127 1 O PHE O 126 N THR O 103
SHEET 5 AD6 5 SER O 201 ILE O 202 1 O SER O 201 N CYS O 127
SHEET 1 AD7 2 MET P 19 GLU P 22 0
SHEET 2 AD7 2 ARG P 29 ASP P 32 -1 O PHE P 31 N VAL P 20
SHEET 1 AD8 5 VAL P 42 THR P 46 0
SHEET 2 AD8 5 ILE P 73 SER P 79 1 O TYR P 76 N LEU P 45
SHEET 3 AD8 5 VAL P 101 ALA P 110 1 O SER P 102 N ILE P 73
SHEET 4 AD8 5 ARG P 132 ILE P 135 1 O MET P 134 N ALA P 109
SHEET 5 AD8 5 ARG P 186 SER P 189 -1 O LEU P 188 N VAL P 133
SHEET 1 AD9 5 VAL P 42 THR P 46 0
SHEET 2 AD9 5 ILE P 73 SER P 79 1 O TYR P 76 N LEU P 45
SHEET 3 AD9 5 VAL P 101 ALA P 110 1 O SER P 102 N ILE P 73
SHEET 4 AD9 5 PHE P 126 CYS P 127 1 O PHE P 126 N THR P 103
SHEET 5 AD9 5 SER P 201 ILE P 202 1 O SER P 201 N CYS P 127
SHEET 1 AE1 2 MET Q 19 GLU Q 22 0
SHEET 2 AE1 2 ARG Q 29 ASP Q 32 -1 O PHE Q 31 N VAL Q 20
SHEET 1 AE2 5 VAL Q 42 THR Q 46 0
SHEET 2 AE2 5 ILE Q 73 SER Q 79 1 O TYR Q 74 N ILE Q 43
SHEET 3 AE2 5 VAL Q 101 ALA Q 110 1 O SER Q 102 N LEU Q 75
SHEET 4 AE2 5 ARG Q 132 ILE Q 135 1 O ARG Q 132 N ALA Q 109
SHEET 5 AE2 5 ARG Q 186 LEU Q 188 -1 O LEU Q 188 N VAL Q 133
SHEET 1 AE3 5 VAL Q 42 THR Q 46 0
SHEET 2 AE3 5 ILE Q 73 SER Q 79 1 O TYR Q 74 N ILE Q 43
SHEET 3 AE3 5 VAL Q 101 ALA Q 110 1 O SER Q 102 N LEU Q 75
SHEET 4 AE3 5 PHE Q 126 CYS Q 127 1 O PHE Q 126 N CYS Q 105
SHEET 5 AE3 5 SER Q 201 ILE Q 202 1 O SER Q 201 N CYS Q 127
SHEET 1 AE4 2 MET R 19 GLU R 22 0
SHEET 2 AE4 2 ARG R 29 ASP R 32 -1 O PHE R 31 N VAL R 20
SHEET 1 AE5 5 VAL R 42 THR R 46 0
SHEET 2 AE5 5 ILE R 73 SER R 79 1 O TYR R 76 N LEU R 45
SHEET 3 AE5 5 VAL R 101 ALA R 110 1 O ILE R 104 N ILE R 77
SHEET 4 AE5 5 ARG R 132 ILE R 135 1 O ARG R 132 N ALA R 109
SHEET 5 AE5 5 ARG R 186 SER R 189 -1 O LEU R 188 N VAL R 133
SHEET 1 AE6 5 VAL R 42 THR R 46 0
SHEET 2 AE6 5 ILE R 73 SER R 79 1 O TYR R 76 N LEU R 45
SHEET 3 AE6 5 VAL R 101 ALA R 110 1 O ILE R 104 N ILE R 77
SHEET 4 AE6 5 ARG R 125 CYS R 127 1 O PHE R 126 N THR R 103
SHEET 5 AE6 5 SER R 201 ILE R 202 1 O SER R 201 N CYS R 127
SHEET 1 AE7 2 MET S 19 ILE S 21 0
SHEET 2 AE7 2 SER S 30 ASP S 32 -1 O PHE S 31 N VAL S 20
SHEET 1 AE8 5 VAL S 42 THR S 46 0
SHEET 2 AE8 5 ILE S 73 SER S 79 1 O TYR S 76 N LEU S 45
SHEET 3 AE8 5 VAL S 101 ALA S 110 1 O SER S 102 N LEU S 75
SHEET 4 AE8 5 ARG S 132 ILE S 135 1 O MET S 134 N ALA S 109
SHEET 5 AE8 5 ARG S 186 SER S 189 -1 O LEU S 188 N VAL S 133
SHEET 1 AE9 5 VAL S 42 THR S 46 0
SHEET 2 AE9 5 ILE S 73 SER S 79 1 O TYR S 76 N LEU S 45
SHEET 3 AE9 5 VAL S 101 ALA S 110 1 O SER S 102 N LEU S 75
SHEET 4 AE9 5 PHE S 126 CYS S 127 1 O PHE S 126 N THR S 103
SHEET 5 AE9 5 SER S 201 ILE S 202 1 O SER S 201 N CYS S 127
SHEET 1 AF1 2 MET T 19 ILE T 21 0
SHEET 2 AF1 2 SER T 30 ASP T 32 -1 O PHE T 31 N VAL T 20
SHEET 1 AF2 5 VAL T 42 THR T 46 0
SHEET 2 AF2 5 ILE T 73 SER T 79 1 O TYR T 76 N LEU T 45
SHEET 3 AF2 5 VAL T 101 ALA T 110 1 O ILE T 104 N ILE T 77
SHEET 4 AF2 5 ARG T 132 ILE T 135 1 O ARG T 132 N ALA T 109
SHEET 5 AF2 5 ARG T 186 SER T 189 -1 O LEU T 188 N VAL T 133
SHEET 1 AF3 5 VAL T 42 THR T 46 0
SHEET 2 AF3 5 ILE T 73 SER T 79 1 O TYR T 76 N LEU T 45
SHEET 3 AF3 5 VAL T 101 ALA T 110 1 O ILE T 104 N ILE T 77
SHEET 4 AF3 5 PHE T 126 CYS T 127 1 O PHE T 126 N CYS T 105
SHEET 5 AF3 5 SER T 201 ILE T 202 1 O SER T 201 N CYS T 127
SHEET 1 AF4 6 THR A 173 ASN A 175 0
SHEET 2 AF4 6 THR A 244 LEU A 248 -1 O SER A 247 N THR A 174
SHEET 3 AF4 6 SER A 280 ILE A 284 1 O PHE A 283 N TYR A 246
SHEET 4 AF4 6 ARG A 317 THR A 323 1 O ARG A 317 N LEU A 282
SHEET 5 AF4 6 PRO A 210 GLY A 214 1 N PRO A 210 O GLY A 320
SHEET 6 AF4 6 GLN A 342 ASP A 345 1 O ILE A 344 N LEU A 211
SHEET 1 AF5 2 ARG A 372 TYR A 373 0
SHEET 2 AF5 2 THR A 420 VAL A 421 1 O VAL A 421 N ARG A 372
SHEET 1 AF6 5 GLU A 515 ASP A 520 0
SHEET 2 AF6 5 ALA A 559 ASP A 564 1 O VAL A 560 N LEU A 517
SHEET 3 AF6 5 VAL A 600 THR A 605 1 O VAL A 600 N LEU A 561
SHEET 4 AF6 5 GLY A 489 ALA A 494 1 N PHE A 493 O MET A 603
SHEET 5 AF6 5 ASN A 646 TRP A 649 1 O ILE A 648 N LEU A 492
SHEET 1 AF7 2 THR A 585 THR A 587 0
SHEET 2 AF7 2 LYS A 593 ASP A 595 -1 O ALA A 594 N LEU A 586
SHEET 1 AF8 3 VAL A 678 VAL A 682 0
SHEET 2 AF8 3 GLY A 729 LEU A 735 1 O VAL A 733 N GLU A 681
SHEET 3 AF8 3 LEU A 742 THR A 743 -1 O THR A 743 N ALA A 734
SHEET 1 AF9 6 THR B 173 ASN B 175 0
SHEET 2 AF9 6 THR B 244 LEU B 248 -1 O SER B 247 N THR B 174
SHEET 3 AF9 6 SER B 280 ILE B 284 1 O PHE B 283 N TYR B 246
SHEET 4 AF9 6 ARG B 317 THR B 323 1 O ILE B 319 N LEU B 282
SHEET 5 AF9 6 PRO B 210 GLY B 214 1 N PRO B 210 O GLY B 320
SHEET 6 AF9 6 GLN B 342 ILE B 346 1 O ILE B 344 N LEU B 211
SHEET 1 AG1 5 GLU B 515 ASP B 520 0
SHEET 2 AG1 5 ALA B 559 ASP B 564 1 O VAL B 560 N LEU B 517
SHEET 3 AG1 5 VAL B 599 THR B 605 1 O VAL B 600 N LEU B 561
SHEET 4 AG1 5 GLY B 489 ALA B 494 1 N PHE B 493 O MET B 603
SHEET 5 AG1 5 ASN B 646 TRP B 649 1 O ILE B 648 N LEU B 492
SHEET 1 AG2 2 THR B 585 THR B 587 0
SHEET 2 AG2 2 LYS B 593 ASP B 595 -1 O ALA B 594 N LEU B 586
SHEET 1 AG3 3 SER B 679 VAL B 682 0
SHEET 2 AG3 3 GLN B 730 ASP B 736 1 O VAL B 733 N GLU B 681
SHEET 3 AG3 3 GLU B 741 GLY B 745 -1 O GLU B 741 N ASP B 736
SHEET 1 AG4 6 THR C 173 ASN C 175 0
SHEET 2 AG4 6 THR C 244 LEU C 248 -1 O SER C 247 N THR C 174
SHEET 3 AG4 6 SER C 280 ILE C 284 1 O PHE C 283 N TYR C 246
SHEET 4 AG4 6 ARG C 317 THR C 323 1 O ILE C 319 N LEU C 282
SHEET 5 AG4 6 PRO C 210 GLY C 214 1 N LEU C 212 O THR C 322
SHEET 6 AG4 6 GLN C 342 ILE C 346 1 O ILE C 344 N LEU C 211
SHEET 1 AG5 5 GLU C 515 ASP C 520 0
SHEET 2 AG5 5 ALA C 559 ASP C 564 1 O VAL C 560 N LEU C 517
SHEET 3 AG5 5 VAL C 599 THR C 605 1 O VAL C 600 N LEU C 561
SHEET 4 AG5 5 GLY C 489 ALA C 494 1 N PHE C 493 O MET C 603
SHEET 5 AG5 5 ASN C 646 TRP C 649 1 O ILE C 648 N LEU C 492
SHEET 1 AG6 2 THR C 585 THR C 587 0
SHEET 2 AG6 2 LYS C 593 ASP C 595 -1 O ALA C 594 N LEU C 586
SHEET 1 AG7 2 LEU C 680 VAL C 682 0
SHEET 2 AG7 2 VAL C 731 VAL C 733 1 O VAL C 733 N GLU C 681
SHEET 1 AG8 6 THR D 173 ASN D 175 0
SHEET 2 AG8 6 THR D 244 LEU D 248 -1 O SER D 247 N THR D 174
SHEET 3 AG8 6 SER D 280 ILE D 284 1 O PHE D 283 N TYR D 246
SHEET 4 AG8 6 VAL D 318 THR D 323 1 O ILE D 319 N ILE D 284
SHEET 5 AG8 6 PRO D 210 GLY D 214 1 N LEU D 212 O GLY D 320
SHEET 6 AG8 6 GLN D 342 ILE D 346 1 O ILE D 344 N LEU D 211
SHEET 1 AG9 5 GLU D 515 ASP D 520 0
SHEET 2 AG9 5 HIS D 558 ASP D 564 1 O LEU D 562 N LEU D 517
SHEET 3 AG9 5 ASN D 598 THR D 604 1 O VAL D 600 N LEU D 561
SHEET 4 AG9 5 GLY D 489 ALA D 494 1 N PHE D 491 O LEU D 601
SHEET 5 AG9 5 ASN D 646 TRP D 649 1 O ILE D 648 N LEU D 492
SHEET 1 AH1 2 THR D 585 THR D 587 0
SHEET 2 AH1 2 LYS D 593 ASP D 595 -1 O ALA D 594 N LEU D 586
SHEET 1 AH2 2 SER D 679 VAL D 682 0
SHEET 2 AH2 2 GLN D 730 VAL D 733 1 O VAL D 733 N GLU D 681
SHEET 1 AH3 6 THR E 174 ASN E 175 0
SHEET 2 AH3 6 THR E 244 LEU E 248 -1 O SER E 247 N THR E 174
SHEET 3 AH3 6 SER E 280 ILE E 284 1 O PHE E 283 N LEU E 248
SHEET 4 AH3 6 ARG E 317 THR E 323 1 O ARG E 317 N LEU E 282
SHEET 5 AH3 6 ASN E 209 GLY E 214 1 N PRO E 210 O GLY E 320
SHEET 6 AH3 6 PHE E 341 ASP E 345 1 O GLN E 342 N LEU E 211
SHEET 1 AH4 2 ARG E 372 TYR E 373 0
SHEET 2 AH4 2 THR E 420 VAL E 421 1 O VAL E 421 N ARG E 372
SHEET 1 AH5 5 LEU E 516 ASP E 520 0
SHEET 2 AH5 5 HIS E 558 ASP E 564 1 O VAL E 560 N LEU E 517
SHEET 3 AH5 5 ASN E 598 THR E 605 1 O VAL E 600 N LEU E 561
SHEET 4 AH5 5 GLY E 489 ALA E 494 1 N PHE E 491 O MET E 603
SHEET 5 AH5 5 ASN E 646 TRP E 649 1 O ILE E 648 N ALA E 494
SHEET 1 AH6 2 THR E 585 THR E 587 0
SHEET 2 AH6 2 LYS E 593 ASP E 595 -1 O ALA E 594 N LEU E 586
SHEET 1 AH7 3 VAL E 678 VAL E 682 0
SHEET 2 AH7 3 GLY E 729 LEU E 735 1 O VAL E 733 N GLU E 681
SHEET 3 AH7 3 GLU E 741 THR E 743 -1 O LEU E 742 N ALA E 734
SHEET 1 AH8 6 THR F 173 ASN F 175 0
SHEET 2 AH8 6 ILE F 245 LEU F 248 -1 O SER F 247 N THR F 174
SHEET 3 AH8 6 ILE F 281 ILE F 284 1 O PHE F 283 N TYR F 246
SHEET 4 AH8 6 ARG F 317 THR F 323 1 O ILE F 319 N ILE F 284
SHEET 5 AH8 6 ASN F 209 GLY F 214 1 N LEU F 212 O THR F 322
SHEET 6 AH8 6 PHE F 341 ASP F 345 1 O ILE F 344 N VAL F 213
SHEET 1 AH9 2 ARG F 372 TYR F 373 0
SHEET 2 AH9 2 THR F 420 VAL F 421 1 O VAL F 421 N ARG F 372
SHEET 1 AI1 5 LEU F 516 ASP F 520 0
SHEET 2 AI1 5 VAL F 560 ASP F 564 1 O LEU F 562 N LEU F 517
SHEET 3 AI1 5 VAL F 600 THR F 605 1 O VAL F 602 N LEU F 561
SHEET 4 AI1 5 GLY F 489 ALA F 494 1 N PHE F 493 O MET F 603
SHEET 5 AI1 5 ASN F 646 TRP F 649 1 O ILE F 648 N LEU F 492
SHEET 1 AI2 2 THR F 585 THR F 587 0
SHEET 2 AI2 2 LYS F 593 ASP F 595 -1 O ALA F 594 N LEU F 586
SHEET 1 AI3 3 SER F 679 VAL F 682 0
SHEET 2 AI3 3 GLN F 730 LEU F 735 1 O VAL F 733 N GLU F 681
SHEET 3 AI3 3 GLU F 741 THR F 743 -1 O LEU F 742 N ALA F 734
SITE 1 AC1 12 LEU A 188 ARG A 191 SER A 216 GLY A 217
SITE 2 AC1 12 GLY A 219 LYS A 220 THR A 221 ALA A 222
SITE 3 AC1 12 ILE A 357 LEU A 361 PRO A 395 ARG F 206
SITE 1 AC2 15 LEU A 459 VAL A 460 PHE A 461 PRO A 496
SITE 2 AC2 15 THR A 497 GLY A 498 VAL A 499 GLY A 500
SITE 3 AC2 15 LYS A 501 THR A 502 GLU A 503 LEU A 653
SITE 4 AC2 15 VAL A 661 ALA A 701 ARG A 702
SITE 1 AC3 15 ALA A 336 ARG A 339 ARG A 340 PRO B 187
SITE 2 AC3 15 LEU B 188 ILE B 189 SER B 216 GLY B 217
SITE 3 AC3 15 GLY B 219 LYS B 220 THR B 221 ALA B 222
SITE 4 AC3 15 THR B 323 ILE B 357 PRO B 395
SITE 1 AC4 13 ARG A 643 LEU B 459 VAL B 460 PHE B 461
SITE 2 AC4 13 GLY B 498 VAL B 499 GLY B 500 LYS B 501
SITE 3 AC4 13 THR B 502 GLU B 503 GLU B 565 LYS B 664
SITE 4 AC4 13 ARG B 702
SITE 1 AC5 15 ARG B 339 ARG B 340 LEU C 188 ILE C 189
SITE 2 AC5 15 SER C 216 GLY C 217 VAL C 218 GLY C 219
SITE 3 AC5 15 LYS C 220 THR C 221 ALA C 222 ILE C 357
SITE 4 AC5 15 PRO C 395 ASP C 396 ILE C 399
SITE 1 AC6 19 GLU B 639 ARG B 643 LEU C 459 VAL C 460
SITE 2 AC6 19 PHE C 461 THR C 497 GLY C 498 VAL C 499
SITE 3 AC6 19 GLY C 500 LYS C 501 THR C 502 GLU C 503
SITE 4 AC6 19 GLU C 565 ASN C 606 VAL C 661 LYS C 664
SITE 5 AC6 19 PHE C 665 ALA C 701 ARG C 702
SITE 1 AC7 16 ARG C 339 ARG C 340 PRO D 187 LEU D 188
SITE 2 AC7 16 ILE D 189 ARG D 191 SER D 216 GLY D 217
SITE 3 AC7 16 VAL D 218 GLY D 219 LYS D 220 THR D 221
SITE 4 AC7 16 ALA D 222 ILE D 357 LEU D 361 ILE D 399
SITE 1 AC8 18 ARG C 643 LEU D 459 VAL D 460 PHE D 461
SITE 2 AC8 18 THR D 497 GLY D 498 VAL D 499 GLY D 500
SITE 3 AC8 18 LYS D 501 THR D 502 GLU D 503 GLU D 565
SITE 4 AC8 18 ASN D 606 VAL D 661 LYS D 664 PHE D 665
SITE 5 AC8 18 ALA D 701 ARG D 702
SITE 1 AC9 13 LEU E 188 ILE E 189 ARG E 191 GLU E 215
SITE 2 AC9 13 SER E 216 GLY E 217 GLY E 219 LYS E 220
SITE 3 AC9 13 ILE E 357 LEU E 361 PRO E 395 ASP E 396
SITE 4 AC9 13 ILE E 399
SITE 1 AD1 14 ARG D 643 LEU E 459 VAL E 460 PHE E 461
SITE 2 AD1 14 THR E 497 VAL E 499 GLY E 500 LYS E 501
SITE 3 AD1 14 THR E 502 GLU E 503 ASN E 606 VAL E 661
SITE 4 AD1 14 LYS E 664 ARG E 702
SITE 1 AD2 10 ARG E 339 GLU F 215 SER F 216 GLY F 217
SITE 2 AD2 10 VAL F 218 GLY F 219 THR F 221 ILE F 357
SITE 3 AD2 10 PRO F 395 ASP F 396
SITE 1 AD3 8 VAL F 460 GLY F 498 VAL F 499 GLY F 500
SITE 2 AD3 8 THR F 502 PHE F 665 ALA F 701 ARG F 702
CRYST1 1.000 1.000 1.000 90.00 90.00 90.00 P 1 1
ORIGX1 1.000000 0.000000 0.000000 0.00000
ORIGX2 0.000000 1.000000 0.000000 0.00000
ORIGX3 0.000000 0.000000 1.000000 0.00000
SCALE1 1.000000 0.000000 0.000000 0.00000
SCALE2 0.000000 1.000000 0.000000 0.00000
SCALE3 0.000000 0.000000 1.000000 0.00000
(ATOM LINES ARE NOT SHOWN.)
END
