KEGG   Syntrophotalea acetylenivorans: A7E78_10905
Entry
A7E78_10905       CDS       T04594                                 
Name
(GenBank) bifunctional homocysteine S-methyltransferase/methylenetetrahydrofolate reductase
  KO
K24042  methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
Organism
pef  Syntrophotalea acetylenivorans
Pathway
pef00270  Cysteine and methionine metabolism
pef00450  Selenocompound metabolism
pef00670  One carbon pool by folate
pef01100  Metabolic pathways
pef01110  Biosynthesis of secondary metabolites
pef01120  Microbial metabolism in diverse environments
pef01230  Biosynthesis of amino acids
Module
pef_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:pef00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    A7E78_10905
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    A7E78_10905
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    A7E78_10905
Enzymes [BR:pef01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.54  methylenetetrahydrofolate reductase (NADH)
     A7E78_10905
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     A7E78_10905
SSDB
Motif
Pfam: S-methyl_trans MTHFR OMPdecase LigA
Other DBs
NCBI-ProteinID: APG28312
UniProt: A0A1L3GQU5
Position
2398680..2400518
AA seq 612 aa
MAQNSRIKGRFLQRLEAGLIIGDGAMGTLLYNRGIPLGHSFEALNLSRPELVEAVHRDYA
AAGAQLLESNTFAANRLALGPLGLDGQVAEINAAGVRLARLAAGVDGLVAGAVGPLPSAK
GQAAELPLAEQRALFSEQMTALAEAGADLFVLETFAGIEELELALQVAEELGLPAVAQMA
FFEEGRTRHGLSAEEVARRLSAAGAAVIGANCGSGPRELLSVLQRMSTVTDRPLSGFANS
GLPQYVNGRYIYLATPEYFADMGREMVAAGACLVGGCCGTTPEHIQALAKSLEEVRPVER
SVPVIKVTEPSAVVEPVPTQRTFLDDWGHRPVVTVELGPPKGLDCRKVLQGAETLAKAGA
DAISLTENPLARIRMGNIALASQIQQQAGIEVIIHITGRDRNLIGLHSELMGAHLLGIRN
VLAITGDPVAVGGEAGASSVFDLNSVGILELLRSLNTGTTLLGADLGGTTRMLAGAAFNP
NVANMSGQIRRMEKKVAAGARFIETQPVYSPEVMLEMLERLAPLNIPVLVGLMPLVSERN
AEFLHNEVPGISLPDEVRQRMRGTSGSSGVEAGMAIARELIDAGRQTVGGFTLMPPFGKV
ELAVELLRYIRG
NT seq 1839 nt   +upstreamnt  +downstreamnt
atggcgcagaacagcagaataaaaggtcgttttttgcaacgtctggaagccggtctgatc
atcggtgacggcgccatgggtacgttgctctataaccgcggaataccactgggccacagc
ttcgaagcactcaacttgagtcgcccggagctggtggaagcggtgcatcgcgattatgcg
gcggccggagcgcagctcctggaaagcaatacctttgccgccaatcgccttgctctcggt
cccctgggtctcgatgggcaagtcgcggaaatcaatgccgcgggagttcgtttggctcgg
ctggccgccggtgttgatggattggtggccggtgcggtaggccctttaccctctgccaag
ggccaagccgcagaactgccccttgccgaacagcgggccctgttcagtgaacagatgacc
gctctggctgaagccggtgctgatctctttgtcctggaaacatttgcgggaatagaggaa
ctggagctggcactgcaagtggcggaagagctcggtctgccagcagtggcgcagatggct
ttctttgaagagggacgcacccgtcacggcttgagcgccgaagaggttgcccgccgattg
agcgcggccggtgcggcggtgatcggtgccaactgtggttccgggccgcgagagttgctg
agcgttctgcagcgcatgtccacggtgaccgaccggcctctgtccggtttcgccaactcc
ggattaccccagtatgtcaacggccgctatatctacctggccacccccgaatattttgcc
gacatggggcgcgagatggttgccgccggggcttgcctggtcggcggttgttgcggcacc
acccccgagcatatccaagcccttgccaagagcctggaagaagtccggcccgtagagcga
tctgtacctgtcattaaggtgaccgagccgtctgctgtcgttgaaccggtgcctacccag
agaacctttctcgatgactggggtcaccggcccgttgtcaccgttgaactcggtcccccc
aagggccttgattgccgcaaggtgctgcagggggccgagactttggccaaggccggcgcc
gatgccatcagcttgacagaaaaccccctggcgcgcattcgcatgggcaacatcgctctg
gccagccaaatccagcaacaggccggaatcgaggtgattattcatatcaccggtcgagac
cgtaacctgatcggtctccattcggagctgatgggagcccatttgctcggtatccgcaac
gtgctggccattaccggagatccggtggcggttggtggcgaggcgggggcgagcagcgtc
ttcgacctcaattccgtcggcattctggaacttctccgttccctgaatacggggactacc
ctgctcggtgcggatcttggcggtactacccggatgctggccggtgcggcgttcaatccc
aatgtggccaatatgagcgggcagattcgcagaatggagaagaaggtagcggcgggtgcg
cggtttatcgagacccaaccggtctattcgccggaagtgatgctggagatgctggaacga
ttggcgccgctgaacattccggtgctggtcggtttaatgcccctggtcagcgagcgcaac
gccgagtttttgcataacgaggttccaggtatctcgctgcccgatgaggtgcggcagcgc
atgcgcggcaccagcggctcctccggggtagaagccggtatggccatcgcgcgggaactg
atcgatgccggccggcagaccgttggcggctttaccctgatgccgcccttcggcaaggtg
gaactggccgtggaactgctgcgctacattcgcggctag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (4)   
   Pfam (4)   
All databases (36)   

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