GenomeNet

Database: Pfam
Entry: Bclx_interact
LinkDB: Bclx_interact
Original site: Bclx_interact 
#=GF ID   Bclx_interact
#=GF AC   PF08945.10
#=GF DE   Bcl-x interacting, BH3 domain
#=GF AU   Mistry J;0000-0003-2479-5322
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   pdb_1pq1
#=GF GA   25.00 25.00;
#=GF TC   27.50 27.50;
#=GF NC   24.00 24.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Bcl-x_interacting_domain
#=GF RN   [1]
#=GF RM   14499110
#=GF RT   The structure of a Bcl-xL/Bim fragment complex: implications for
#=GF RT   Bim function. 
#=GF RA   Liu X, Dai S, Zhu Y, Marrack P, Kappler JW; 
#=GF RL   Immunity. 2003;19:341-352.
#=GF RN   [2]
#=GF RM   9704409
#=GF RT   Bcl-2-family proteins: the role of the BH3 domain in apoptosis.
#=GF RA   Kelekar A, Thompson CB;
#=GF RL   Trends Cell Biol. 1998;8:324-330.
#=GF RN   [3]
#=GF RM   10816098
#=GF RT   Role of the BH3 (Bcl-2 homology 3) domain in the regulation of
#=GF RT   apoptosis and Bcl-2-related proteins.
#=GF RA   Lutz RJ;
#=GF RL   Biochem Soc Trans. 2000;28:51-56.
#=GF DR   INTERPRO; IPR015040;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This domain is a long alpha helix, required for interaction with
#=GF CC   Bcl-x. It is found in BAM, Bim and Bcl2-like protein 11 [1].
#=GF CC   This domain is also known as the BH3 domain between residues 146
#=GF CC   and 161.
#=GF SQ   108
#=GS F6YSA1_CALJA/42-79        AC F6YSA1.1
#=GS Q3KPZ6_XENLA/128-164      AC Q3KPZ6.1
#=GS F7HHA7_MACMU/130-166      AC F7HHA7.2
#=GS B2L11_RAT/128-165         AC O88498.1
#=GS A0A1V4IG33_PATFA/2-40     AC A0A1V4IG33.1
#=GS K7GA86_PELSI/160-198      AC K7GA86.1
#=GS G1LDR8_AILME/128-165      AC G1LDR8.1
#=GS A0A1U8D6N6_ALLSI/80-118   AC A0A1U8D6N6.1
#=GS E7FF06_DANRE/105-142      AC E7FF06.1
#=GS F1SU81_PIG/128-165        AC F1SU81.3
#=GS F7HHA1_MACMU/41-76        AC F7HHA1.2
#=GS A0A2K5NTQ5_CERAT/130-166  AC A0A2K5NTQ5.1
#=GS W5PY58_SHEEP/128-165      AC W5PY58.1
#=GS A0A1S3N4A1_SALSA/132-170  AC A0A1S3N4A1.1
#=GS A0A286XJN2_CAVPO/128-164  AC A0A286XJN2.1
#=GS A0A093GNE7_DRYPU/53-91    AC A0A093GNE7.1
#=GS G3W979_SARHA/131-168      AC G3W979.1
#=GS A0A1L8G1Y7_XENLA/127-164  AC A0A1L8G1Y7.1
#=GS A0A2K5HZD9_COLAP/130-166  AC A0A2K5HZD9.1
#=GS F7CXT2_MONDO/130-168      AC F7CXT2.1
#=GS A0A151M1P8_ALLMI/109-147  AC A0A151M1P8.1
#=GS Q2YDF0_BOVIN/72-109       AC Q2YDF0.1
#=GS A0A2D0QP40_ICTPU/257-291  AC A0A2D0QP40.1
#=GS C3XZ81_BRAFL/410-450      AC C3XZ81.1
#=GS G3H020_CRIGR/72-109       AC G3H020.1
#=GS A0A1L8G7D9_XENLA/128-164  AC A0A1L8G7D9.1
#=GS G7PMY2_MACFA/130-166      AC G7PMY2.1
#=GS A0A1S3FHA8_DIPOR/72-109   AC A0A1S3FHA8.1
#=GS A0A2I2UX96_FELCA/72-109   AC A0A2I2UX96.1
#=GS A0A0D9RWE0_CHLSB/70-106   AC A0A0D9RWE0.1
#=GS L5LIN7_MYODS/72-110       AC L5LIN7.1
#=GS A0A2K5HZB5_COLAP/130-166  AC A0A2K5HZB5.1
#=GS A0A2I3RH84_PANTR/130-167  AC A0A2I3RH84.1
#=GS G5BQZ0_HETGA/132-168      AC G5BQZ0.1
#=GS H0XW23_OTOGA/132-168      AC H0XW23.1
#=GS B8JK68_DANRE/105-142      AC B8JK68.1
#=GS A0A2I3HW02_NOMLE/41-76    AC A0A2I3HW02.1
#=GS A0A2I2ZL36_GORGO/130-166  AC A0A2I2ZL36.1
#=GS F6XMC1_CALJA/132-169      AC F6XMC1.1
#=GS M3YDI3_MUSPF/164-201      AC M3YDI3.1
#=GS C1KGB6_PIG/128-165        AC C1KGB6.1
#=GS G1MV54_MELGA/6-44         AC G1MV54.1
#=GS A0A1S3ABB1_ERIEU/72-109   AC A0A1S3ABB1.1
#=GS A0A1U7T0S6_TARSY/42-79    AC A0A1U7T0S6.1
#=GS A0A1S3SAH9_SALSA/138-174  AC A0A1S3SAH9.1
#=GS C1KGB7_PIG/72-109         AC C1KGB7.1
#=GS A0A2K5HZ87_COLAP/70-106   AC A0A2K5HZ87.1
#=GS A0A226MFT9_CALSU/25-63    AC A0A226MFT9.1
#=GS A0A2I2UKP4_FELCA/128-165  AC A0A2I2UKP4.1
#=GS A0A2I3M6I1_PAPAN/130-166  AC A0A2I3M6I1.1
#=GS A0A1U8DE80_ALLSI/131-169  AC A0A1U8DE80.1
#=GS G1PDJ5_MYOLU/1-38         AC G1PDJ5.1
#=GS A0A2I2Z4Y0_GORGO/41-76    AC A0A2I2Z4Y0.1
#=GS A0A2G8K3I0_STIJA/42-79    AC A0A2G8K3I0.1
#=GS W5UEE7_ICTPU/153-187      AC W5UEE7.1
#=GS A0A2K5NU22_CERAT/70-106   AC A0A2K5NU22.1
#=GS L5KV50_PTEAL/128-166      AC L5KV50.1
#=GS H2R0F7_PANTR/130-166      AC H2R0F7.1
#=GS A0A1U7SU38_TARSY/72-109   AC A0A1U7SU38.1
#=GS A0A1U7T0R1_TARSY/132-169  AC A0A1U7T0R1.1
#=GS A0A2D0QR27_ICTPU/141-175  AC A0A2D0QR27.1
#=GS A0A286XLU5_CAVPO/72-108   AC A0A286XLU5.1
#=GS A0A151M1P7_ALLMI/113-151  AC A0A151M1P7.1
#=GS A0A1U8DFM5_ALLSI/84-122   AC A0A1U8DFM5.1
#=GS A0A1U8D3X6_ALLSI/136-174  AC A0A1U8D3X6.1
#=GS A0A096NYC3_PAPAN/130-166  AC A0A096NYC3.1
#=GS H2P5E2_PONAB/70-106       AC H2P5E2.1
#=GS Q4KMV9_XENTR/128-164      AC Q4KMV9.1
#=GS A0A1S3FFM9_DIPOR/132-169  AC A0A1S3FFM9.1
#=GS A0A226P2P5_COLVI/8-46     AC A0A226P2P5.1
#=GS V4AL96_LOTGI/255-299      AC V4AL96.1
#=GS G3SU55_LOXAF/131-168      AC G3SU55.1
#=GS A0A2I3T769_PANTR/41-76    AC A0A2I3T769.1
#=GS B2L11_MOUSE/128-165       AC O54918.1
#=GS B2L11_MOUSE/128-165       DR PDB; 1PQ1 B; 83-109;
#=GS A0A091DA59_FUKDA/42-78    AC A0A091DA59.1
#=GS A0A2I2YV25_GORGO/130-167  AC A0A2I2YV25.1
#=GS A0A1U8BW10_MESAU/128-165  AC A0A1U8BW10.1
#=GS F7A7D2_HORSE/128-164      AC F7A7D2.1
#=GS A0A2I3MSA0_PAPAN/130-167  AC A0A2I3MSA0.1
#=GS A0A1U7TC61_TARSY/42-79    AC A0A1U7TC61.1
#=GS S7NWQ0_MYOBR/72-110       AC S7NWQ0.1
#=GS F7HHA9_MACMU/130-167      AC F7HHA9.2
#=GS A0A2K5HZD0_COLAP/130-167  AC A0A2K5HZD0.1
#=GS A0A2I3SWR7_PANTR/70-106   AC A0A2I3SWR7.1
#=GS A0A151M1M7_ALLMI/108-146  AC A0A151M1M7.1
#=GS A0A2I3LPR5_PAPAN/70-106   AC A0A2I3LPR5.1
#=GS A0A1S3N4L1_SALSA/137-175  AC A0A1S3N4L1.1
#=GS G1QPE5_NOMLE/130-166      AC G1QPE5.1
#=GS A0A1S3WMP2_ERIEU/128-165  AC A0A1S3WMP2.1
#=GS A0A287DFJ0_ICTTR/72-109   AC A0A287DFJ0.1
#=GS F6XLL7_CALJA/132-168      AC F6XLL7.1
#=GS G3R8Z8_GORGO/130-166      AC G3R8Z8.2
#=GS J9NWV6_CANLF/128-165      AC J9NWV6.1
#=GS A0A2K5NU95_CERAT/130-166  AC A0A2K5NU95.1
#=GS F7FTC8_ORNAN/75-113       AC F7FTC8.2
#=GS G1SSY0_RABIT/126-163      AC G1SSY0.1
#=GS F6XLH3_CALJA/132-169      AC F6XLH3.1
#=GS F6Y9Z6_CALJA/72-109       AC F6Y9Z6.1
#=GS A0A2I2Y4B3_GORGO/70-106   AC A0A2I2Y4B3.1
#=GS A0A1S3IS10_LINUN/230-269  AC A0A1S3IS10.1
#=GS A0A2K5NTS9_CERAT/41-76    AC A0A2K5NTS9.1
#=GS A0A2K5HZB9_COLAP/41-76    AC A0A2K5HZB9.1
#=GS A0A2I3GAG2_NOMLE/130-166  AC A0A2I3GAG2.1
#=GS B2L11_HUMAN/130-166       AC O43521.1
#=GS B2L11_HUMAN/130-166       DR PDB; 4ZIH B; 144-159;
#=GS B2L11_HUMAN/130-166       DR PDB; 5VWZ B; 141-166;
#=GS B2L11_HUMAN/130-166       DR PDB; 3KJ1 B; 1-21;
#=GS B2L11_HUMAN/130-166       DR PDB; 4A1W P; 207-223;
#=GS B2L11_HUMAN/130-166       DR PDB; 5WOS B; 54-74;
#=GS B2L11_HUMAN/130-166       DR PDB; 4YJ4 B; 146-163;
#=GS B2L11_HUMAN/130-166       DR PDB; 2YQ6 B; 147-164;
#=GS B2L11_HUMAN/130-166       DR PDB; 5AGX C; 1-21;
#=GS B2L11_HUMAN/130-166       DR PDB; 2WH6 B; 51-72;
#=GS B2L11_HUMAN/130-166       DR PDB; 2V6Q B; 51-73;
#=GS B2L11_HUMAN/130-166       DR PDB; 5AGW C; 1-19;
#=GS B2L11_HUMAN/130-166       DR PDB; 3IO8 D; 53-71;
#=GS B2L11_HUMAN/130-166       DR PDB; 2YQ7 B; 147-164;
#=GS B2L11_HUMAN/130-166       DR PDB; 5VX2 D; 51-75;
#=GS B2L11_HUMAN/130-166       DR PDB; 3KJ2 B; 1-21;
#=GS B2L11_HUMAN/130-166       DR PDB; 4A1W R; 207-223;
#=GS B2L11_HUMAN/130-166       DR PDB; 5VWY B; 141-165;
#=GS B2L11_HUMAN/130-166       DR PDB; 2NL9 B; 53-75;
#=GS B2L11_HUMAN/130-166       DR PDB; 5VX3 B; 84-104;
#=GS B2L11_HUMAN/130-166       DR PDB; 5VX3 H; 84-106;
#=GS B2L11_HUMAN/130-166       DR PDB; 3KJ0 B; 1-23;
#=GS B2L11_HUMAN/130-166       DR PDB; 5AGX D; 1-21;
#=GS B2L11_HUMAN/130-166       DR PDB; 3FDL B; 84-108;
#=GS B2L11_HUMAN/130-166       DR PDB; 2K7W B; 145-164;
#=GS B2L11_HUMAN/130-166       DR PDB; 3D7V B; 53-75;
#=GS B2L11_HUMAN/130-166       DR PDB; 4A1W Q; 206-223;
#=GS B2L11_HUMAN/130-166       DR PDB; 2VM6 B; 141-165;
#=GS B2L11_HUMAN/130-166       DR PDB; 5VX3 D; 85-106;
#=GS B2L11_HUMAN/130-166       DR PDB; 4D2M D; 53-73;
#=GS B2L11_HUMAN/130-166       DR PDB; 5VX0 B; 141-165;
#=GS B2L11_HUMAN/130-166       DR PDB; 4ZIE C; 143-164;
#=GS B2L11_HUMAN/130-166       DR PDB; 5VWW D; 143-161;
#=GS B2L11_HUMAN/130-166       DR PDB; 4QVF B; 54-74;
#=GS B2L11_HUMAN/130-166       DR PDB; 4ZIF B; 144-159;
#=GS B2L11_HUMAN/130-166       DR PDB; 5VWW C; 142-166;
#=GS B2L11_HUMAN/130-166       DR PDB; 5C3G B; 90-105;
#=GS B2L11_HUMAN/130-166       DR PDB; 5AGW D; 1-21;
#=GS B2L11_HUMAN/130-166       DR PDB; 5VX0 D; 142-165;
#=GS B2L11_HUMAN/130-166       DR PDB; 5VX2 B; 53-75;
#=GS B2L11_HUMAN/130-166       DR PDB; 4UF3 B; 56-73;
#=GS B2L11_HUMAN/130-166       DR PDB; 5VWX D; 142-164;
#=GS B2L11_HUMAN/130-166       DR PDB; 5VX3 F; 85-106;
#=GS B2L11_HUMAN/130-166       DR PDB; 4D2M B; 53-74;
#=GS B2L11_HUMAN/130-166       DR PDB; 3IO9 B; 53-75;
#=GS B2L11_HUMAN/130-166       DR PDB; 5VWV B; 141-165;
#=GS B2L11_HUMAN/130-166       DR PDB; 4B4S B; 53-76;
#=GS B2L11_HUMAN/130-166       DR PDB; 5VWX B; 142-164;
#=GS B2L11_HUMAN/130-166       DR PDB; 3IO8 B; 54-76;
#=GS B2L11_HUMAN/130-166       DR PDB; 5VWZ D; 141-166;
#=GS B2L11_HUMAN/130-166       DR PDB; 4A1W S; 206-223;
#=GS A0A2K5NTR8_CERAT/130-167  AC A0A2K5NTR8.1
#=GS A0A2I3SN61_PANTR/130-166  AC A0A2I3SN61.1
#=GS I3NFA5_ICTTR/128-165      AC I3NFA5.1
#=GS R4G9R5_ANOCA/50-88        AC R4G9R5.1
F6YSA1_CALJA/42-79                   ............ASMRQSQAEPAG..MRPEIWIAQELRRIGDEFNAYYP-R..R-l.....
Q3KPZ6_XENLA/128-164                 .......amaar--------NPVD.qMTPELWIAQELRRIGDEFNASFTPR..R-a.....
F7HHA7_MACMU/130-166                 .........ama---SRRQAEPAD..MRPEIRIAQELRRIGDEFNAYYA--..RR......
B2L11_RAT/128-165                    ............ASIRQSQEEPED..LRPEIRIAQELRRIGDEFNETYT-R..R-a.....
A0A1V4IG33_PATFA/2-40                ............ASRWPSPSLAED..LQPEIWIAQELRRIGDEFNASYCPR..RG......
K7GA86_PELSI/160-198                 ............ASRWESPSIRED..MQPEIWIAQELRRIGDEFNASYCPR..RG......
G1LDR8_AILME/128-165                 ............ASMRQSQAVPAD..MRPEIWIAQELRRIGDEFNAYYP-R..R-v.....
A0A1U8D6N6_ALLSI/80-118              ............ASRWQYRSIPED..MQPEIWIAQELRRIGDEFNASYCPR..RG......
E7FF06_DANRE/105-142                 ............SHQHLQMAAPVA.aLPPEMVVARELRRIGDEFNRLYC--..--el....
F1SU81_PIG/128-165                   ............ASMRQSQAEPAD..MRPEIWIAQELRRIGDEFNAYYP-R..R-v.....
F7HHA1_MACMU/41-76                   .........qas----RRQAEPAD..MRPEIRIAQELRRIGDEFNAYYA--..RR......
A0A2K5NTQ5_CERAT/130-166             .........ama---SRRQAEPAD..MRPEIRIAQELRRIGDEFNAYYA--..RR......
W5PY58_SHEEP/128-165                 ............ASMRQSQAVPAD..TRPEIWIAQELRRIGDEFNAYYP-R..R-v.....
A0A1S3N4A1_SALSA/132-170             ..........py----RSRPPPTAgdMRPEILIGQELQRIGDEFNNLIIHR..R-i.....
A0A286XJN2_CAVPO/128-164             ............ASMRQSQAGPPH..LRPEIWIAQELRRIGDEFNASYP--..RR......
A0A093GNE7_DRYPU/53-91               ............ASRWPSPSAAED..IQPEIWIAQELRRIGDEFNASYCPR..RG......
G3W979_SARHA/131-168                 ............ASMRQSQSIPAD..MRPEIWIAQELRRIGDEFNASYP-R..RG......
A0A1L8G1Y7_XENLA/127-164             ....samaarnl---------VDQ..MTPELWIAQELRRIGDDFNASFAPR..RG......
A0A2K5HZD9_COLAP/130-166             .........ama---SRRQAEPAD..MRPEIRIAQELRRIGDEFNAYYA--..RR......
F7CXT2_MONDO/130-168                 ............ASMRQSQSIPAD..MRPEIWIAQELRRIGDEFNASYYPR..RG......
A0A151M1P8_ALLMI/109-147             ............ASRWQYRSIPED..MQPEIWIAQELRRIGDEFNASYCPR..RG......
Q2YDF0_BOVIN/72-109                  ............ASMRQSQAVPAD..TRPEIWIAQELRRIGDEFNAYYP-R..R-v.....
A0A2D0QP40_ICTPU/257-291             ........gaas---------AGD..MQAELEIARELRRIGDEFNQLYF--..--heaer.
C3XZ81_BRAFL/410-450                 ............QFRARSRSEPVR..VSPEELVARELRRISDEFDSLVFSPtqRR......
G3H020_CRIGR/72-109                  ............ASIRQSQEEPAD..IRPEIWIAQELRRIGDEFNESYR-R..R-a.....
A0A1L8G7D9_XENLA/128-164             .......amaar--------NPVD.qMTPELWIAQELRRIGDEFNASFTPR..RG......
G7PMY2_MACFA/130-166                 .........ama---SRRQAEPAD..MRPEIRIAQELRRIGDEFNAYYA--..RR......
A0A1S3FHA8_DIPOR/72-109              ............ASMRQSQEEPAD..LRPEIWIAQELRRIGDEFDAYYP-R..R-v.....
A0A2I2UX96_FELCA/72-109              ............ASMRQPQAVPAD..MRPEIWIAQELRRIGDEFNAYYP-R..R-v.....
A0A0D9RWE0_CHLSB/70-106              .........ama---SRRQAEPAD..MRPEIRIAQELRRIGDEFNAYYA--..RR......
L5LIN7_MYODS/72-110                  ............ASMRQSQALPAD..MRPEMWIAQELRRIGDEFNNSYRNP..RR......
A0A2K5HZB5_COLAP/130-166             .........ama---SRRQAEPAD..MRPEIRIAQELRRIGDEFNAYYA--..RR......
A0A2I3RH84_PANTR/130-167             .......amasm-----RQAEPAD..MRPEIWIAQELRRIGDEFNAYYA-R..R-m.....
G5BQZ0_HETGA/132-168                 ............ASMRQSQAEPPD..MRPEIWIAQELRRIGDEFNASYP--..RR......
H0XW23_OTOGA/132-168                 ............ASMRQSQAEPAD..LRPEMWIAQELRRIGDEFNAYYP--..--tr....
B8JK68_DANRE/105-142                 ............SHQHLQMAAPVA.aLPPEMVVARELRRIGDEFNRLYC--..--ea....
A0A2I3HW02_NOMLE/41-76               ........qasm-----RQAEPAD..MRPEIWIAQELRRIGDEFNAYYA--..RR......
A0A2I2ZL36_GORGO/130-166             .......amasm-----RQAEPAD..MRPEIWIAQELRRIGDEFNAYYA--..RR......
F6XMC1_CALJA/132-169                 ............ASMRQSQAEPAG..MRPEIWIAQELRRIGDEFNAYYP-R..R-v.....
M3YDI3_MUSPF/164-201                 ............ASRRQSQAVPAD..MRPEMWIAQELRRIGDEFNAYYP-R..R-v.....
C1KGB6_PIG/128-165                   ............ASMRQSQAEPAD..MRPEIWIAQELRRIGDEFNAYYP-R..R-v.....
G1MV54_MELGA/6-44                    ............ASRWRSHSLAEE..IQPEIWIAQELRRIGDEFNASYCPR..RG......
A0A1S3ABB1_ERIEU/72-109              ............ASMRQSQAVPAD..MRPEIWIAQELRRIGDEFNAYYP-R..R-v.....
A0A1U7T0S6_TARSY/42-79               ...........e-SMRQSQAEPPD..MRPEIWIAQELRRIGDEFNAYYP-R..R-l.....
A0A1S3SAH9_SALSA/138-174             .....yrprppp--------TAGD..MWPETLIGQELQRIGDEFNDLVMHR..--l.....
C1KGB7_PIG/72-109                    ............ASMRQSQAEPAD..MRPEIWIAQELRRIGDEFNAYYP-R..R-v.....
A0A2K5HZ87_COLAP/70-106              .........ama---SRRQAEPAD..MRPEIRIAQELRRIGDEFNAYYA--..RR......
A0A226MFT9_CALSU/25-63               ............ASRWRSHSLAEE..IQPEIWIAQELRRIGDEFNASYCPR..RG......
A0A2I2UKP4_FELCA/128-165             ............ASMRQPQAVPAD..MRPEIWIAQELRRIGDEFNAYYP-R..R-v.....
A0A2I3M6I1_PAPAN/130-166             .........ama---SRRQAEPAD..MRPEIRIAQELRRIGDEFNAYYA--..RR......
A0A1U8DE80_ALLSI/131-169             ............ASRWQYRSIPED..MQPEIWIAQELRRIGDEFNASYCPR..RG......
G1PDJ5_MYOLU/1-38                    ............-SMQQSQALPVD..MRPEMWIAQELRRIGDEFNNSYRNP..RR......
A0A2I2Z4Y0_GORGO/41-76               ........qasm-----RQAEPAD..MRPEIWIAQELRRIGDEFNAYYA--..RR......
A0A2G8K3I0_STIJA/42-79               ...........t-FRDRANSAPSR.pSQSAIEVGRELRRISDEFESTFY--..--qg....
W5UEE7_ICTPU/153-187                 ........gaas---------AGD..MQAELEIARELRRIGDEFNQLYF--..--heaer.
A0A2K5NU22_CERAT/70-106              .........ama---SRRQAEPAD..MRPEIRIAQELRRIGDEFNAYYA--..RR......
L5KV50_PTEAL/128-166                 ............ASLRQSQALPAD..LRPETWIAQELRRIGDEFNASYP-R..R-vr....
H2R0F7_PANTR/130-166                 .......amasm-----RQAEPAD..MRPEIWIAQELRRIGDEFNAYYA--..RR......
A0A1U7SU38_TARSY/72-109              ...........e-SMRQSQAEPPD..MRPEIWIAQELRRIGDEFNAYYP-R..R-a.....
A0A1U7T0R1_TARSY/132-169             ...........e-SMRQSQAEPPD..MRPEIWIAQELRRIGDEFNAYYP-R..R-a.....
A0A2D0QR27_ICTPU/141-175             ........gaas---------AGD..MQAELEIARELRRIGDEFNQLYF--..--heaer.
A0A286XLU5_CAVPO/72-108              ............ASMRQSQAGPPH..LRPEIWIAQELRRIGDEFNASYP--..RR......
A0A151M1P7_ALLMI/113-151             ............ASRWQYRSIPED..MQPEIWIAQELRRIGDEFNASYCPR..RG......
A0A1U8DFM5_ALLSI/84-122              ............ASRWQYRSIPED..MQPEIWIAQELRRIGDEFNASYCPR..RG......
A0A1U8D3X6_ALLSI/136-174             ............ASRWQYRSIPED..MQPEIWIAQELRRIGDEFNASYCPR..RG......
A0A096NYC3_PAPAN/130-166             .........ama---SRRQAEPAD..MRPEIRIAQELRRIGDEFNAYYA--..RR......
H2P5E2_PONAB/70-106                  .......amasm-----RQAEPAD..MRPEIWIAQELRRIGDEFNAYYA--..RR......
Q4KMV9_XENTR/128-164                 .......amadr--------NPVN.qMSPELWIAQELRRIGDDFNASFSPR..RG......
A0A1S3FFM9_DIPOR/132-169             ............ASMRQSQEEPAD..LRPEIWIAQELRRIGDEFDAYYP-R..R-v.....
A0A226P2P5_COLVI/8-46                ............ASRWRSHSLAEE..IQPEIWIAQELRRIGDEFNASYCPR..RG......
V4AL96_LOTGI/255-299                 vrdrsvslpdmq---------ALR..VQRELEVGRELRRLSDEFNTSYS-R..--grerrr
G3SU55_LOXAF/131-168                 ............ASMRQSQALPAD..LRPEIWIARELRRIGDEFNAYYP-R..R-a.....
A0A2I3T769_PANTR/41-76               ........qasm-----RQAEPAD..MRPEIWIAQELRRIGDEFNAYYA--..RR......
B2L11_MOUSE/128-165                  ............ASIRQSQEEPED..LRPEIRIAQELRRIGDEFNETYT--..RRv.....
#=GR B2L11_MOUSE/128-165       SS    ............XXXXXXXXXXX-..--HHHHHHHHHHHHHHHHHHHHH--..HHH.....
A0A091DA59_FUKDA/42-78               ............ASLRQSQAEPPD..MRPEIWIAQELRRIGDEFNASYP--..RR......
A0A2I2YV25_GORGO/130-167             .......amasm-----RQAEPAD..MRPEIWIAQELRRIGDEFNAYYA-R..R-m.....
A0A1U8BW10_MESAU/128-165             ............ASIRQSQEEPAD..IRPEIWIAQELRRIGDEFNESYR--..RRv.....
F7A7D2_HORSE/128-164                 ............ASMRQSQAVPAD..MRPEVWIAQELRRIGDEFNASYP--..RR......
A0A2I3MSA0_PAPAN/130-167             .........ama---SRRQAEPAD..MRPEIRIAQELRRIGDEFNAYYA-R..R-m.....
A0A1U7TC61_TARSY/42-79               ...........e-SMRQSQAEPPD..MRPEIWIAQELRRIGDEFNAYYP-R..R-a.....
S7NWQ0_MYOBR/72-110                  ............ASMRQSQALPAD..MRPEMWIAQELRRIGDEFNNSYRNP..RR......
F7HHA9_MACMU/130-167                 .........ama---SRRQAEPAD..MRPEIRIAQELRRIGDEFNAYYA-R..R-m.....
A0A2K5HZD0_COLAP/130-167             .........ama---SRRQAEPAD..MRPEIRIAQELRRIGDEFNAYYA-R..R-m.....
A0A2I3SWR7_PANTR/70-106              .......amasm-----RQAEPAD..MRPEIWIAQELRRIGDEFNAYYA--..RR......
A0A151M1M7_ALLMI/108-146             ............ASRWQYRSIPED..MQPEIWIAQELRRIGDEFNASYCPR..RG......
A0A2I3LPR5_PAPAN/70-106              .........ama---SRRQAEPAD..MRPEIRIAQELRRIGDEFNAYYA--..RR......
A0A1S3N4L1_SALSA/137-175             ..........py----RSRPPPTAgdMRPEILIGQELQRIGDEFNNLIIHR..R-i.....
G1QPE5_NOMLE/130-166                 .......amasm-----RQAEPAD..MRPEIWIAQELRRIGDEFNAYYA--..RR......
A0A1S3WMP2_ERIEU/128-165             ............ASMRQSQAVPAD..MRPEIWIAQELRRIGDEFNAYYP-R..R-v.....
A0A287DFJ0_ICTTR/72-109              ............ASMRESQAEPAD..MRPEIWIAQELRRIGDEFN-LYYPR..R-v.....
F6XLL7_CALJA/132-168                 ............ASMRQSQAEPAG..MRPEIWIAQELRRIGDEFNAYYP-R..R-......
G3R8Z8_GORGO/130-166                 .......amasm-----RQAEPAD..MRPEIWIAQELRRIGDEFNAYYA--..RR......
J9NWV6_CANLF/128-165                 ............ASMRQSQAVPAD..MRPEIWIAQELRRIGDEFNAYYP-R..R-v.....
A0A2K5NU95_CERAT/130-166             .........ama---SRRQAEPAD..MRPEIRIAQELRRIGDEFNAYYA--..RR......
F7FTC8_ORNAN/75-113                  ............ASIRQPQSVPED..MRPEIWIAQELRRIGDEFNASYCPR..RG......
G1SSY0_RABIT/126-163                 ............ASMRQSQAEPAD..TRPETWIAQELRRIGDEFNAYYP-R..R-v.....
F6XLH3_CALJA/132-169                 ............ASMRQSQAEPAG..MRPEIWIAQELRRIGDEFNAYYP-R..R-i.....
F6Y9Z6_CALJA/72-109                  ............ASMRQSQAEPAG..MRPEIWIAQELRRIGDEFNAYYP-R..R-v.....
A0A2I2Y4B3_GORGO/70-106              .......amasm-----RQAEPAD..MRPEIWIAQELRRIGDEFNAYYA--..RR......
A0A1S3IS10_LINUN/230-269             ...........v-SRGRAMSVPALrrIRTESEIGQELRRISDEFHLSYRS-..--ey....
A0A2K5NTS9_CERAT/41-76               .........qas----RRQAEPAD..MRPEIRIAQELRRIGDEFNAYYA--..RR......
A0A2K5HZB9_COLAP/41-76               .........qas----RRQAEPAD..MRPEIRIAQELRRIGDEFNAYYA--..RR......
A0A2I3GAG2_NOMLE/130-166             .......amasm-----RQAEPAD..MRPEIWIAQELRRIGDEFNAYYA--..RR......
B2L11_HUMAN/130-166                  .......amasm-----RQAEPAD..MRPEIWIAQELRRIGDEFNAYYA--..RR......
#=GR B2L11_HUMAN/130-166       SS    .......XXXXX-----XXXXXXX..HHHHHHHHHHHHHHHHHHHHHHH--..HX......
A0A2K5NTR8_CERAT/130-167             .........ama---SRRQAEPAD..MRPEIRIAQELRRIGDEFNAYYA-R..R-m.....
A0A2I3SN61_PANTR/130-166             .......amasm-----RQAEPAD..MRPEIWIAQELRRIGDEFNAYYA--..RR......
I3NFA5_ICTTR/128-165                 ............ASMRESQAEPAD..MRPEIWIAQELRRIGDEFN-LYYPR..R-v.....
R4G9R5_ANOCA/50-88                   ...........t-SRWQSRPIPED..MQPEIWIAQELRRIGDEFNASHCPR..RG......
#=GC SS_cons                         .......XXXXX-----XXXXXXX..HHHHHHHHHHHHHHHHHHHHHHH--..HHH.....
#=GC seq_cons                        ...............tppQAtPAD..MRPEIWIAQELRRIGDEFNAhYs....R.......
//
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