GenomeNet

Database: Pfam
Entry: Conotoxin
LinkDB: Conotoxin
Original site: Conotoxin 
#=GF ID   Conotoxin
#=GF AC   PF02950.20
#=GF DE   Conotoxin
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Pfam-B_529 (release 6.4)
#=GF GA   25.10 25.10;
#=GF TC   25.20 25.20;
#=GF NC   24.70 25.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Conotoxin
#=GF WK   Contryphan
#=GF CL   CL0083
#=GF RC   Review
#=GF RN   [1]
#=GF RM   3052286
#=GF RT   Peptide toxins from venomous Conus snails. 
#=GF RA   Gray WR, Olivera BM, Cruz LJ; 
#=GF RL   Annu Rev Biochem 1988;57:665-700.
#=GF RN   [2]
#=GF RM   8230223
#=GF RT   Three-dimensional structure in solution of the calcium channel
#=GF RT   blocker omega-conotoxin 
#=GF RA   Pallaghy PK, Duggan BM, Pennington MW, Norton RS; 
#=GF RL   J Mol Biol 1993;234:405-420.
#=GF DR   INTERPRO; IPR004214;
#=GF DR   SCOP; 2cco; fa;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Conotoxins are small snail toxins that block ion channels.
#=GF SQ   10
#=GS W7XJE7_TETTS/1-74      AC W7XJE7.1
#=GS W7X9R5_TETTS/2-81      AC W7X9R5.1
#=GS A0A7E6FTS7_OCTVU/1-85  AC A0A7E6FTS7.1
#=GS A0A166MGQ5_9AGAM/4-78  AC A0A166MGQ5.1
#=GS B5YI56_THEYD/3-80      AC B5YI56.1
#=GS A0A1B8GMV0_9PEZI/1-72  AC A0A1B8GMV0.1
#=GS A0A4P8YEF8_9ENTR/1-62  AC A0A4P8YEF8.1
#=GS A0A2Z6S4P7_9GLOM/1-78  AC A0A2Z6S4P7.1
#=GS A0A1W4WZH9_AGRPL/4-89  AC A0A1W4WZH9.1
#=GS A0A1D2NAF4_ORCCI/2-80  AC A0A1D2NAF4.1
W7XJE7_TETTS/1-74                 ..........................mktsay------LIALLLLLS....TFFLL.....LT.KQQAkiEDS.NLINEVQIPEQPE..SA--..NLK...CIDNFHPC...-SNDHDCCSQ...SCH..LWLCI...........
W7X9R5_TETTS/2-81                 ..........................rfnlva------LILLVLFVFs.naHLRMA.....EE.TQAQ..TET.QPQAEAETQTEGK..VEPL..M--...CQRQGQLC...GIGLPSCCSG...LCCnySFGC-qrc........
A0A7E6FTS7_OCTVU/1-85             ................................MKIIILLSILLILLQ....--AYT.....GT.SRRY..YAR.HKLEALARYQSHR.rRKQT..ERT...CSKWRETCqpwSNSKSKCCDPsslVCK..-----cnlwmqncrc.
A0A166MGQ5_9AGAM/4-78             ...........................stvfa-----MLAAATVSVS....AVSTA.....DT.NAAR..LARgLAPKAPTKRDTAR..RSAA..SGE...CKPLLQSC...-AVNSECCAD...LCL..LGLC-g..........
B5YI56_THEYD/3-80                 ............................kkly------LIIVLLFAFlvvgFAVAQ.....NK.DNST..AFQ.KVDYCLAMNVDGK..MENMisAKP...CTPSGWWC...-TSSGQCCSG...RCT..NNVC-d..........
A0A1B8GMV0_9PEZI/1-72             mkfyvaatilaltvgamsvavpegfnealnva---------------....-----.....--.----..---.-----VREAVTNP..SNSA..TGE...CRPALQSC...-DRNSECCSR...FCL..LGLC-l..........
A0A4P8YEF8_9ENTR/1-62             .............................mkn-----VLIIAALLLP...lTAMAQ.....PLtPQQQ..HQR.QQIRNQQMMNNPT..QQRM..QQE...SQ------...----------...---..-----srqiqqqgrln
A0A2Z6S4P7_9GLOM/1-78             ...............................m-----IFIVSLCFLTl.niEAHYQ.....HQ.RRSS..TAT.TIKSKRHPTKPKT..NAKS..INSpkiCVPSGTFC..sPNSKPPCCSG...FCY..RHKCV...........
A0A1W4WZH9_AGRPL/4-89             ..............................sw--LPVVLSILVLLAAv..yPQVHAgpyldED.DYDQ..LSE.QYSDN--TLDRML..QPAQ..KRA...CIRRGGNC...DHRPNDCCYN..sSCR..C----nlwgsncrc..
A0A1D2NAF4_ORCCI/2-80             ............................mnlr--------VCVVLLAs..lYFCIA.....QY.DEEY..EEQ.DISFNGNSLDYSE..DYRD..KRQ...CLGKWARC..qYDSGPSCCNG...YCH..-----qdidasygnc.
#=GC seq_cons                     ..............................hh......Lhlhllhls...hhhhht.....pp.sppp..ttp.ph.pshpphsssc..pppt..ppp...Cpsphp.C....sssspCCus...hCp....hC.p..........
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