#=GF ID Csm1_N
#=GF AC PF18504.5
#=GF DE Csm1 N-terminal domain
#=GF AU El-Gebali S;0000-0003-1378-5495
#=GF SE ECOD:EUF05456
#=GF GA 26.30 26.30;
#=GF TC 26.30 26.50;
#=GF NC 26.20 26.10;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP Coiled-coil
#=GF RN [1]
#=GF RM 20723757
#=GF RT The monopolin complex crosslinks kinetochore components to
#=GF RT regulate chromosome-microtubule attachments.
#=GF RA Corbett KD, Yip CK, Ee LS, Walz T, Amon A, Harrison SC;
#=GF RL Cell. 2010;142:556-567.
#=GF DR INTERPRO; IPR041671;
#=GF DR SO; 0001080; coiled_coil;
#=GF CC In the budding yeast Saccharomyces cerevisiae, sister chromatid
#=GF CC co-orientation in meiosis I depends on the four-protein
#=GF CC monopolin complex (Mam1, Csm1, Lrs4, and Hrr25/casein kinase 1),
#=GF CC which localizes to centromeres from meiotic prophase through
#=GF CC metaphase I. Csm1 and Lrs4, form a complex that resides in the
#=GF CC nucleolus during interphase and relocalizes to centromeres
#=GF CC during meiotic prophase, accompanied by phosphorylation of Lrs4.
#=GF CC This is the N-terminal domain of Csm1 which forms a coiled-coil
#=GF CC [1].
#=GF SQ 31
#=GS Q6CKJ3_KLULA/1-70 AC Q6CKJ3.1
#=GS I2H5E5_TETBL/2-71 AC I2H5E5.1
#=GS A7TFZ2_VANPO/2-71 AC A7TFZ2.1
#=GS A0A4C2E436_9SACH/1-69 AC A0A4C2E436.1
#=GS G0VER7_NAUCC/1-70 AC G0VER7.1
#=GS A0A7J7IHD3_9RHOD/316-384 AC A0A7J7IHD3.1
#=GS A0A1G4JNI1_9SACH/1-70 AC A0A1G4JNI1.1
#=GS A0A4Y8IHN3_9BACI/106-171 AC A0A4Y8IHN3.1
#=GS A0A7H9HWI1_9SACH/1-70 AC A0A7H9HWI1.1
#=GS A0A376BAC8_9ASCO/25-94 AC A0A376BAC8.1
#=GS CSM1_YEAST/1-70 AC P25651.1
#=GS A0A1S7HNY6_9SACH/1-69 AC A0A1S7HNY6.1
#=GS G8C0R1_TETPH/2-71 AC G8C0R1.1
#=GS Q751E1_ASHGO/1-70 AC Q751E1.1
#=GS A0A7H9B4X9_ZYGMR/1-70 AC A0A7H9B4X9.1
#=GS A0A1G4ILN9_9SACH/1-70 AC A0A1G4ILN9.1
#=GS G8JQ87_ERECY/24-93 AC G8JQ87.1
#=GS Q6FVN3_CANGA/1-70 AC Q6FVN3.1
#=GS A0A1G4M994_LACFM/1-70 AC A0A1G4M994.1
#=GS A0A0C7N3D1_9SACH/1-70 AC A0A0C7N3D1.1
#=GS J7S2J4_KAZNA/1-70 AC J7S2J4.1
#=GS J8LQT7_SACAR/1-70 AC J8LQT7.1
#=GS A0A1E5R1G5_9ASCO/16-85 AC A0A1E5R1G5.1
#=GS A0A1X7R5E9_9SACH/1-71 AC A0A1X7R5E9.1
#=GS G0WFM8_NAUDC/4-73 AC G0WFM8.1
#=GS C5DC27_LACTC/1-70 AC C5DC27.1
#=GS G8ZNB7_TORDC/1-70 AC G8ZNB7.1
#=GS A0A1S7HKA6_9SACH/1-69 AC A0A1S7HKA6.1
#=GS M1VGV8_CYAM1/345-410 AC M1VGV8.1
#=GS J5PIX1_SACK1/1-70 AC J5PIX1.1
#=GS H2B131_KAZAF/1-70 AC H2B131.1
Q6CKJ3_KLULA/1-70 ......MDPLAEYKESVQDRLEKADLAVQGVLNENVKLMRQLELKQQEIESLKEQLQSDKTKISQLEDSKADAEEQ......
I2H5E5_TETBL/2-71 ......VDPLVEYKNSVEKRLNDAELLINRLIHENSVKDQLLEQRDEEISQLKATIEKLDEKSSSQLKKYDLSLEN......
A7TFZ2_VANPO/2-71 .....s-DSFIQYKKSIKERLDNADLLVSKVIHENTLLSQQLDSRNEEISYMKEKLDKHKTKVDSLNDKITKQNEN......
A0A4C2E436_9SACH/1-69 ......MDVLSQYRDSVKERLENADVLVSKLVHENTILEQNLEIRNQELESSRRRIKELEEQLKQSDESM------elvkd.
G0VER7_NAUCC/1-70 ......MDPLTQYKESVKEQSENAELLIAKLIHENSVLTTKNDTYSQEVETLRLQMAKLQEQLKVSEELRKKQAEN......
A0A7J7IHD3_9RHOD/316-384 ....ir--AFEEYRASVAAQLDAAERLVERYKSENEQLRTQLSS-DAEPAKLRQRLEELERERAEQQVRY------lelenr
A0A1G4JNI1_9SACH/1-70 ......MDALTQYKTSIQSRLDSADILVSKLIHENRMLSQELENKDEEMDSLKRQLELARKRNEEFDKKCSTAEEE......
A0A4Y8IHN3_9BACI/106-171 kqnldd----------VRDRLKHSDDYVNKLTQEKAQLEQTVSDKDTEIGRLEDQIANRNMKYDQLMEDYQD----mqmr..
A0A7H9HWI1_9SACH/1-70 ......MDALTQYRNSVKERLDSADVLVAKLVHENTVLSQTVETRTQEVENVRQQLKTLQDRVAELESREARQEEE......
A0A376BAC8_9ASCO/25-94 .....n-DILYKYKQSVQKRLDSGDLLISKLIHENTLLKQQLDNKQQEIDILQDKIVKLDEICQNLNRGNLKCKE-d.....
CSM1_YEAST/1-70 ......MDPLTVYKNSVKQQIDSADLLVANLVNENFVLSEKLDTKATEIKQLQKQIDSLNAQVKELKTQTSQQAEN......
A0A1S7HNY6_9SACH/1-69 ......MDALTQYKNSVQQRLDNADLLVAKLVHENTILGQTIELRNQALEASESQIKELKDRIKDLEESM------elvkd.
G8C0R1_TETPH/2-71 .....a-NTLEQYKKLIGERLDNADLLVSKLVLENSLLKQQLESKDEQLKLLNGRLEHLAAQEQRHASALQDANE-a.....
Q751E1_ASHGO/1-70 ......MDPLSRYKQAVQQRLDSAERAVSKVVHENTVLAQQLATREKEVAALQAQVAEAEEARARAQTRQATLEEE......
A0A7H9B4X9_ZYGMR/1-70 ......MDSLTQYRDSIKERLDNADLLVAKLVHENTVLTQTVETKTQEIEGFQQQIHGLEEKVRELTSLQAKQEEN......
A0A1G4ILN9_9SACH/1-70 ......MEPLVEYRKAVQERLNNADVLVAKLVHENGLAAQELENKQQELELLRSRLDERDDRLRQADKARAAAVEE......
G8JQ87_ERECY/24-93 ......MDPLSRYKHAVQQRLDNAELAVSKVVYENTLLSQQLSTKDQEIKRLREQVLELEEDGRQIDEKRRQLQEE......
Q6FVN3_CANGA/1-70 ......MDPLSEYKKSVQKRLDAADLLVERVVQENTLLRQKLDSRDVELESVKEQLAVLRSKRDELDERSQKDKET......
A0A1G4M994_LACFM/1-70 ......MDPLVEYKNSVQNRLDNADILVSRLVHENSLLSQEVENRDQEIETLKRQLETHKREEEERQHRMTSLEEE......
A0A0C7N3D1_9SACH/1-70 ......MDPLVQYKASIQNRLDSADVLVSKLVHENRMLAQETENKDEEIKALKQQLESIKKRNEEDEKRANVAEEE......
J7S2J4_KAZNA/1-70 ......MNALQEYKDSVQERLNSADLLVSKAVHENSILTERLETQERELEALRKRVAELEVDCQGAKDDRNSSVED......
J8LQT7_SACAR/1-70 ......MDPLTVYKNSVKQQIDSADLLVANLVNENFILSEKMNTKSTEIEQLQKQIDSLNTEVKDLKTQVSQQTEN......
A0A1E5R1G5_9ASCO/16-85 .....n-DEIVQYKKLLNKRLEKSDLLINQLLLENEMLQKKLDTLSIQHAGLQQEYKQTCDKLVLIDEKLNEQED-n.....
A0A1X7R5E9_9SACH/1-71 ......MDTLVEYKKSVQKQLESNELLVAKLVHENTLLTQQLEGKTQQLELLQDELKKLKETRVSLQKELDTHQ--dev...
G0WFM8_NAUDC/4-73 ......MDPLTTYKRSIQERLDAADVLVSKLTLENSLLNTAVDTHKQEVQSLKKQVKTLNEQLDGSKTSNEKQKET......
C5DC27_LACTC/1-70 ......MDPISQYKAAVQSRLDNADILVSKLVHENRMLAQDVENKDQEIESLKRQLAAAEARSKECEERTGAAEEE......
G8ZNB7_TORDC/1-70 ......MDALTQYKRALQEQLESADLLIAKLVHENTVLSQTVETRTKKNQGLQERLQSVEERVKDLESRETKQEES......
A0A1S7HKA6_9SACH/1-69 ......MDALTQYKNSIQQRLDNADLLVAKLVHENTILGQTIELRNQALEASESQIKELKDRIKDLEESM------elvkd.
M1VGV8_CYAM1/345-410 ....ra---FEEYRASVAVQLDAAERLVERYKSENEQLRQQLDH--AEVAKLRQRVDDLERTRTDQQLR-------ylelqk
J5PIX1_SACK1/1-70 ......MDPLTVYKNSLKQQIDSADLLVANLVNENFMLSEKLDAKSSEIKQLQKQIDSLNGQMTDLKTQVSHQTEN......
H2B131_KAZAF/1-70 ......MEALIEYKESVKEQLENADLLITKLVNENSTLNEKLRVKDDRISNLENEIANLKQQVVKTQQQLKDKAEN......
#=GC seq_cons ......MDsLspYKpSVppRLDsADLLVuKLVaENolLsQpL-s+spElctLcpplcpLccchpphccphpptpEp......
//
