GenomeNet

Database: Pfam
Entry: DCA16
LinkDB: DCA16
Original site: DCA16 
#=GF ID   DCA16
#=GF AC   PF15349.6
#=GF DE   DDB1- and CUL4-associated factor 16
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   Jackhmmer:Q9NXF7
#=GF GA   27.00 27.00;
#=GF TC   32.10 356.60;
#=GF NC   22.30 19.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   16949367
#=GF RT   A family of diverse Cul4-Ddb1-interacting proteins includes
#=GF RT   Cdt2, which is required for S phase destruction of the
#=GF RT   replication factor Cdt1.
#=GF RA   Jin J, Arias EE, Chen J, Harper JW, Walter JC;
#=GF RL   Mol Cell. 2006;23:709-721.
#=GF DR   INTERPRO; IPR028216;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   DCA16 is a family of eukaryotic proteins that interacts with
#=GF CC   DDB1 and CUL4A. The family may function as a substrate receptor
#=GF CC   for the CUL4-DDB1 E3 ubiquitin-protein ligase complex [1].
#=GF SQ   24
#=GS A0A0D9SEA2_CHLSB/1-216  AC A0A0D9SEA2.1
#=GS M3WWE4_FELCA/1-216      AC M3WWE4.1
#=GS D2I3G1_AILME/1-216      AC D2I3G1.1
#=GS F7EKV9_MACMU/1-216      AC F7EKV9.1
#=GS A0A287BMS6_PIG/1-206    AC A0A287BMS6.1
#=GS A0A2K5JHD3_COLAP/1-216  AC A0A2K5JHD3.1
#=GS DCA16_HUMAN/1-216       AC Q9NXF7.1
#=GS I3LXM4_ICTTR/1-216      AC I3LXM4.1
#=GS W5NQN1_SHEEP/1-216      AC W5NQN1.1
#=GS A0A2K5KTT6_CERAT/1-216  AC A0A2K5KTT6.1
#=GS G8F3M7_MACFA/1-216      AC G8F3M7.1
#=GS G1Q9T8_MYOLU/1-170      AC G1Q9T8.1
#=GS A0A1U7TUQ5_TARSY/1-216  AC A0A1U7TUQ5.1
#=GS H2QP99_PANTR/1-216      AC H2QP99.1
#=GS G3MXE6_BOVIN/1-161      AC G3MXE6.1
#=GS L5K4J6_PTEAL/1-216      AC L5K4J6.1
#=GS A0A096NAI0_PAPAN/1-216  AC A0A096NAI0.1
#=GS F7ENH7_CALJA/1-216      AC F7ENH7.1
#=GS S7NCP4_MYOBR/1-180      AC S7NCP4.1
#=GS H2PCZ7_PONAB/1-216      AC H2PCZ7.1
#=GS A0A1S3EL14_DIPOR/1-216  AC A0A1S3EL14.1
#=GS G1TTJ9_RABIT/1-216      AC G1TTJ9.1
#=GS F6UDX6_HORSE/1-216      AC F6UDX6.1
#=GS DCA16_BOVIN/1-175       AC Q2HJA2.1
A0A0D9SEA2_CHLSB/1-216             MGPRNPSPDHLSDSESEEEENISYLNESSGEEWDSSEEEDSMVPNLSPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDPSTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLTSPSRLSRDHATLNGALQFATKQLSRTLSRATPIPEYLKQIPNSCVSGCCCGWLTKTVKETTRTEPINTTYSYTDFQKAVNKLLTASL.....
M3WWE4_FELCA/1-216                 MGPRNPSPDPLSESESEEEENANYLNESSGQEWDSSEEEDPVVPNLTPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDPSTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLTNPSRLSRDHATLNGALQFATKQLSRTLSRATPIPEYLKQIPNSCVSGCCCGWLTKTVKETTRTEPINTTYSYTDFQKAVNKLLTASL.....
D2I3G1_AILME/1-216                 MGPRNPSPDPLSESESEEEGNANYLNESSGQEWDSSEGEDPVVPNVSPLESLAWQVKCLLKYSTTWKPLHPNSWLYHAKLLDPSTPVHILREIGLRLSHCSHCVPRLEPIPEWPPLASCGVPPFQKPLTNASRLSRDHATLNGALQFATKQLSRTLSRATPIPEYLKQIPNSCVSGCCCGWLTKTVKETTRTEPINTTYSYTDFQKAVNKLLTASL.....
F7EKV9_MACMU/1-216                 MGPRNPSPDHLSDSESEAEENISYLNESSGEEWDSSEEEDSMVPNLSPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDPSTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLTSPSRLSRDHATLNGALQFATKQLSRTLSRATPIPEYLKQIPNSCVSGCCCGWLTKTVKETTRTEPINTTYSYTDFQKAVNKLLTASL.....
A0A287BMS6_PIG/1-206               MGPRNPSPDPLSESESEEEENANYLNESSGEERDSSEEEDPVVSCLTPLESLAWQVKCLLKYSTTWKPLNRNS----------CTPVHILRGIGLRLSHCSHCVPKLEPISEWPPLASWGVPPFQKPLMNPSWLSRDHATLNGALQLATKQLSQTLSRATLIPEYLRQIPNSCVSGCCCGWLTKTVKETTRTKHINTTYSYTDFQKAVNKLLTASL.....
A0A2K5JHD3_COLAP/1-216             MGPRNPSPDHLSDSESEEEENISYLNESSGEEWDSSEEEDSTVPNLSPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDPSTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLTSPSRLSRDHATLNGALQFATRQLSRTLSRATPIPEYLKQIPNSCVSGCCCGWLTKTVKETTRTEPINTTYSYTDFQKAVNKLLTASL.....
DCA16_HUMAN/1-216                  MGPRNPSPDHLSESESEEEENISYLNESSGEEWDSSEEEDSMVPNLSPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDPSTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLTSPSRLSRDHATLNGALQFATKQLSRTLSRATPIPEYLKQIPNSCVSGCCCGWLTKTVKETTRTEPINTTYSYTDFQKAVNKLLTASL.....
I3LXM4_ICTTR/1-216                 MGPRNPSPDPLSESESEEEENISYLNESSGEEWDSSEEDDPKVPNLTPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDPSTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLTSSSRLSRDHASLNGALQFATKQLSRTLSRATPIPEYLKQNPNTCVSGCCCGWLTKTVKETTRTEPINTTYSYTDFQKAVNKLLTASL.....
W5NQN1_SHEEP/1-216                 MGPRNPSPDPLSESESEEEENTNYLNESSGEEWDSSEEEDPVVPNLTPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDASTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLLSPSRLSREHATLNGALQFATKQLSRTLSRATPIPEYLKQVPNSCVSGCCCGWLTKTVKETTRTEPINTTYSYTDFQKAVNKLLTASL.....
A0A2K5KTT6_CERAT/1-216             MGPRNPSPDHLSDSESEEEENISYLNESSGEEWDSSEEEDSMVPNLSPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDPSTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLTSPSRLSRDHATLNGALQFATKQLSRTLSRATPIPEYLKQIPNSCVSGCCCGWLTKTVKETTRTEPINTTYSYTDFQKAVNKLLTASL.....
G8F3M7_MACFA/1-216                 MGPRNPSPDHLSDSESEAEENISYLNESSGEEWDSSEEEDSMVPNLSPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDPSTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLTSPSRLSRDHATLNGALQFATKQLSRTLSRATPIPEYLKQIPNSCVSGCCCGWLTKTVKETTRTEPINTTYSYTDFQKAVNKLLTASL.....
G1Q9T8_MYOLU/1-170                 MGPRIPSPDRLTESESEEEESANYLNESFGEDWDYSEEEDPVVPNLTRLESLAWQVKCLLKYSTTWRPLNPNSWLYHARLLDQDTPVHILREIGLRLSYCSHCVPKLEPIPEWPPLASCGVPPFQKPLTSPSRLSRDHATLNGALQFATKQLSRTLSKATPIPEFLKQIP----------------------------------------------.....
A0A1U7TUQ5_TARSY/1-216             MGPRNPSPDPLSESESEEEENISYLNESSGQEWDSSEEEDPIVPNLTPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDPSTPVHILREIGLRLSHCSQCVPKLEPIPEWPPLASCGVPPFQKPLMNPSRLSRDYATLNGALQFATKQLSRTLSRATPIPEYLKQIPNSCVSGCCCGWLTKTVKETTRTEPINTTYSYTDFQKAVNKLLTASL.....
H2QP99_PANTR/1-216                 MGPRNPSPDHLSESESEEEENISYLNESSGEEWDSSEEEDSMVPNLSPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDPSTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLTSPSRLSRDHATLNGALQFATKQLSRTLSRATPIPEYLKQIPNSCVSGCCCGWLTKTVKETTRTEPINTTYSYTDFQKAVNKLLTASL.....
G3MXE6_BOVIN/1-161                 MGPRNPSPDPLSESESEEEENTNYLNESSGEEWDSSEEEDPVVPNLTPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDASTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLISPSRLSRDHATLNGALQFATKQLSRTLSRATP-------------------------------------------------------.....
L5K4J6_PTEAL/1-216                 MGPRNPSPDPLSESESEEEESANYLNESSGEEWDSSEEEDPVVPNLTPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDPSTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLTSPSRLSRDHATLNGALQFATKQLSRTLSRATPIPEYLKQIPNSCVSGCCCGWLTKTVKETTRTEPINTTYSYTDFQKAVNKLLTASL.....
A0A096NAI0_PAPAN/1-216             MGPRNPSPDHLSDSESEEEENISYLNESSGEEWDSSEEEDSMVPNLSPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDPSTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLTSPSRLSRDHATLNGALQFATKQLSRTLSRATPIPEYLKQIPNSCVSGCCCGWLTKTVKETTRTEPINTTYSYTDFQKAVNKLLTASL.....
F7ENH7_CALJA/1-216                 MGPRNPSPDHLSESESEEEENMSYLNESSGEEWDSSEEEDSMVPNLSPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDPSTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLTSPSRLSRDHATLNGALQFATKQLSRTLSRATPIPEYLKQIPNSCVSGCCCGWLTKTVKETTRTEPINTTYSYTDFQKAVNKLLTASL.....
S7NCP4_MYOBR/1-180                 MGPRIPSPDRLTESESEEEESANYLNESFGEDWDYSEEEDPVVPNLTRLESLAWQVKCLLKYSTTWRPLNPNSWLYHARLLDQDTPVHILREIGLRLSYCSHCVPKLEPIPEWPPLASCGVPPFQKPLTSPSRLSRDHATLNGALQFATKQLSRTLSKATPIPEFLKQIPNSCVSGCCCG------------------------------------.....
H2PCZ7_PONAB/1-216                 MGPRNPSPDHLSESESEEEENISYLNESSGEEWDSSEEEDSMVPNLSPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDPSTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLTSPSRLSRDHATLNGALQFATKQLSRTLSRATPIPEYLKQIPNSCVSGCCCGWLTKTVKETTRTEPINTTYSYTDFQKAVNKLLTASL.....
A0A1S3EL14_DIPOR/1-216             MGPRIPSPDRLSESESEEEDNISYLDESSGEEWDSSEEEDPMVPNLTPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDPSTPVHILREIGLRLSHCSHCVPRLEPIPEWPPLASCGVPPFQKPLTSPSRLSRDHATLNGALQFATKQLRRTLSRATPIPEYLKQIPNSCVSGCCCGWLTKTVKETTRTEPINTTYSYTDFQKAVNKLLTASL.....
G1TTJ9_RABIT/1-216                 MGPRNPSPDPLSESESEEEENFSYLNENSGEEWDSSEEEDPMVPNLTPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDPSTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLISPSRLSRDRATLNGALQFATKQLSRTLSRATPIPEYLKQIPNSCVSGCCCGWLTKTVKETTRTEPINTTYSYTDFQKAVNKLLTASL.....
F6UDX6_HORSE/1-216                 MGPRNPSPDPLSESESEEEENAKYLNESSGEEWDSSEEEDPVVPNLTPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDLSTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLISPSRLSRDHATLNGALQFATKQLSRTLSRATPIPEYLKQIPNSCVSGCCCGWLTKTVKETTRTEPINTTYSYTDFQKAVNKLLTASL.....
DCA16_BOVIN/1-175                  MGPRNPSPDPLSESESEEEENTNYLNESSGEEWDSSEEEDPVVPNLTPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDASTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLISPSRLSRDHATLNGALQFATKQLSRTLSRATPHAFLPKLVP----------------------------------------------lafss
#=GC seq_cons                      MGPRNPSPD.LSESESEEEENhsYLNESSGEEWDSSEEEDshVPNLoPLESLAWQVKCLLKYSTTWKPLNPNSWLYHAKLLDPSTPVHILREIGLRLSHCSHCVPKLEPIPEWPPLASCGVPPFQKPLTSPSRLSRDHATLNGALQFATKQLSRTLSRATPIPEYLKQIPNSCVSGCCCGWLTKTVKETTRTEPINTTYSYTDFQKAVNKLLTASL.....
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