#=GF ID   DUF3573
#=GF AC   PF12097.12
#=GF DE   Protein of unknown function (DUF3573)
#=GF AU   Assefa S;0000-0003-2178-533X
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   PFAM-B_2286 (release 23.0)
#=GF GA   26.60 26.60;
#=GF TC   26.80 28.80;
#=GF NC   26.30 26.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF CL   CL0193
#=GF DR   INTERPRO; IPR021956;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family of proteins is functionally uncharacterised. This
#=GF CC   protein is found in bacteria. Proteins in this family are
#=GF CC   typically between 372 to 530 amino acids in length.
#=GF SQ   11
#=GS Q5NIP1_FRATT/1-374        AC Q5NIP1.1
#=GS Q5NGC6_FRATT/98-340       AC Q5NGC6.1
#=GS Q5NI23_FRATT/16-237       AC Q5NI23.1
#=GS A0A8J3E9F4_9GAMM/71-327   AC A0A8J3E9F4.1
#=GS A0A0K2DUN8_PISSA/100-299  AC A0A0K2DUN8.1
#=GS A0A371RF89_9PROT/62-241   AC A0A371RF89.1
#=GS A0A8J3EAA4_9GAMM/3-236    AC A0A8J3EAA4.1
#=GS Q5NGC7_FRATT/4-422        AC Q5NGC7.1
#=GS A0A095DMF9_PISSA/63-294   AC A0A095DMF9.1
#=GS Q5NH68_FRATT/10-373       AC Q5NH68.1
#=GS A0A1E3GDA8_9GAMM/83-291   AC A0A1E3GDA8.1
Q5NIP1_FRATT/1-374                   ............................................MLNKINIVFICFLVLSITPFMGFS..........................NSFKNSNEQSQKSNSIDKQGITQLQSQIANIQAEINHLTQIKNS.......NNSAQFATYSSKVENIGLPNSLPDN---------...NKLTLDIMTNIDSDSSIINLSDCSIGGIFDKDGGINVGGAPAITTQGEV.TFLGAYSGNNTVPIGMISSNLFASTVMGLRNKFDSYSIFFGGKIEADAQLWFGSSTIS-......NKAT....NLASNGQ...N...I..SLTAANLYFLSNVGHYVTAEIEFNTTEL......NNF..SLGNAFVIFGNLDTSPFFLTAGRNK.LSVGAFGGGGPWTGGIT.kNFL..SPGKVTNVSLNYKSDVWNANVAVFG....S....NDNQFNFSTGLFYAQKWTQDIAVGFNTGYVYNMAGAGNPSLSRFLQSQGHPTDTIGSF............................
Q5NGC6_FRATT/98-340                  ......................................slsssd------------------------..........................--------------------------------------------.......----------------------------------...-------------------------------DREVDVGNQVKITTQGEI.SYVGSFSSNNTVPIGQLPSNLFASSILRQRAFFDDYSIFFGGFIQADAQIWNGTDITT-......RNGG....NFTGNGE...N...I..YLTSATLYFLANLGHYVTANLDFVANQN......NNY..DLQDAFVIFGNLDTTPVFVSVGKYR.PSVGSFGGGGPWTSGIT.aNMF..RPLRVTNAAINYRGDTSNANFTVFD....A....K-NHATFSVAYFDAVSIPNIAQVGFNLGYMHDIRGANN--------------------rfnfidkr....................
Q5NI23_FRATT/16-237                  .........................................mkn------------------------..........................--------------------------------------------.......----------------------------------...-------------------------------------------------.---------------RISKNLYASTIIGQRDKFPNYSMFFGGYFEGDAQTWFGSQINRA......GGTS....DFPATGQ...N...I..YMTTVDLYFLANVGEYMTAVFDFLTDDN......SDF..GLRNGFVILGNLDTSPFFVTVGKNRrISVGTYGGGGPWSNGLS.eDFL..APGSVTNISLNYKTSSINANVTTFG....T....QNNHLDFSAAIFYANKLTTDLSYGLNFGYIFNLAGADNTSISKFLDSIDKGNDSVGT-i...........................
A0A8J3E9F4_9GAMM/71-327              .............................gtgtdstdhvtvptn------------------------..........................--------------------------------------------.......----------------------------------...---------------------------------------------MGQIqNFLFSDVHDGVIPMGMLSSSQFALGLLKQRNMYSDRALVFGGYLEADPQVWNGSKIVRN......NVGTetgvQTYQSGK...G...L..PITTANLYVAANLGRYVTAETTLAADPS......DGYkvNAQDAFVMFGNLDDFPLYATVGKNR.LAFGSFSGGGPWTGSLT..QML.fRPGRVNNVSLAYYKDGLSSNLTLFQ....T....DDHTSDFVYAAFYGNEI-GKLAYGINGGYVYNVSGTGNSSF-NLATNPGPSKTRIGA-v...........................
A0A0K2DUN8_PISSA/100-299             .........pllsigglletdigygrntnldadyfhksqslshs------------------------..........................--------------------------------------------.......----------------------------------...-------------------------------------------------.-----------------------------------------------------------......----....-------...D...A..EVTAARLHIMANINDWTTGFFYYDML-A......NNL..RTGK--ITFGNLNETPFYASIGKSY.SYFGNWSGPNIITTDVD..ASL..FESRSNNAMLGYTQGGFNAQVGLTSpastVntpnHNNHAGFLTQAHYTLDLGNNNSAYLGAGYMSDLHGTEVSALSQAQAADGH--------tripaa......................
A0A371RF89_9PROT/62-241              ....................................eagelktn------------------------..........................--------------------------------------------.......----------------------------------...-------------------------------------------------.------------------------------------SIYVGGLIRGGLYKEQTNTAGKFpi..lsRFPF....QHDSDTD...N...TeaLIQNAAVTFTGNFGKWITGFAQIEHSEVfyrpdqDNV..QLREAYVIFGNLEQSPFYAAVGRKT.VDFGQFDTFTPFTHSVNqhYFW..TLSDDPVVEVGYIGDTFRVS-----....-....----------------------------------------------------------gtlingsrqmrvaysdnddvfgnfav..
A0A8J3EAA4_9GAMM/3-236               ......................................snlheg------------------------..........................--------------------------------------------.......----------------------------------...-------------------------------------------------.----------GLPFGKMNSSQFGLNILQHRNKYSDKALVFGGYLEADGSVWNGSTIVRAnrtaksEKVV....NTYQSGK...G...L..YLTTAALYTAANLGRYVTAEMTLLGNEN......TSP..VVSDAFVMFGNLDDFPVYATVGKNR.LPIGSFAGGGVWTGSLV..QML.fRPNRVTNASVAYFDHGLSANVTLFQ....T....DDHTSDFSSALFYGKQIEQ-WLLGMNVGYVHDVNGTGNPSFNAATRSGTADKTRIGA-v...........................
Q5NGC7_FRATT/4-422                   ..........................................kf--KKTCLIVSSLLACSGLAYSEDSpqvvsqggplgatsigdqnlgqpdpnASGASSTTQTTGSNLNDRELLLKLQQQVQQLQGQLQQLKAQGNGgglqntyNGSSQFTTYSSKVDGNKNPRTLGGNGESKDLSQAligGQTSSDIMGNVNASNSIINLASEPLGGVFNQKGGIDVGGAPAITTQGQV.TYLGSYSGNNSIPIGQISSNLFASTLLGQREKFDDYSVFFGGFIEADAQAWFGSAVTKV......QNAG....QLSSNGQ...N...I..YLTSANLYFLSNLGHYVTAQFDFDTNES......GSF..SLGNAFVIFGNLDISPFFVTAGRNK.LSVGSYGGGGTWTSGIT..KFL..SPNQVTNVSIDYKDQVWNANIAVFG....S....DDRRANFSTGLFYADSWTPNLAAGFNVGYVFNIAGAGNSSIANSLANLNRSSDNVGAL............................
A0A095DMF9_PISSA/63-294              .....................pigggmiagqssrfgrdlqmlgl------------------------..........................--------------------------------------------.......----------------------------------...-------------------------------------------------.---------------------------LQKAGKDAPRLTIGGNLEADV--VYGRNVADGs....sIYNS....QGYVKGQ...NasaI..FLDTARLDLLAKLNDWAFVDWQLDFASG......ADT..R--SGYLTIGNLDKSPVYLSAGKYF.PYFGDFGGHVYNNPLST.dYFR..ISSAVGAIALGYSQDNLNVSAALFK....S....K--RANVTQ----VKDWTLQANYSFKVGQVKAKVGAGY--------------------vaditghalsditaqntldalpaanvsa
Q5NH68_FRATT/10-373                  ............................................YIYKKLLIY-SFFMCSIC------..........................HSYAELNNQIS---------ILELQKQIKELQTEINHFEETKI-.......NENFEFTTYSSEVVDSK---SKLRNKETKVLYTV...QNNNVDIIQNISPESTIIDLRGKPLGKIFNQNGSIDVGNAPAITTDGQA.AYLGSYSGNNSIPIGMIPGKLFASTIILQKEKFDQYSIFLGGLIRVDAQTWFGDSIPRVdf..nnNPTT....SFDSKGQ...N...I..YPSTARLFFLANMGNYITAAYNVSTSEL......NNF..NIGDAFVIIGNMDVSPYFITVGKST.LTIANLGGGGPSTSGIA..NFL..NTGRATNISLNYKTSTLNVSVAFFS....T....NDQKANFSAGLFYADKWTDNLSVGFNTGYVYDLAGAENSSIPRIALN-----KTIGAFsi..........................
A0A1E3GDA8_9GAMM/83-291              lkllkkagedaprftlggileadisygkdttaadsgvagdgiyn------------------------..........................--------------------------------------------.......----------------------------------...-------------------------------------------------.-----------------------------------------------------------......---T....NGYAEGQtasS...I..YLDTVRLDILAKLNDWVLVDWQLDIAKS......SPL..RT--GFVTFGNLSKSPVYFSLGKIV.PYFGDFGGHTYNNPLST..DYFriSKGKLA-GTLGYYQDNLNISASVFE....T....DRGTAA----DNHVNDWTLQANYAFKVGQVKAKVGAG---------------------yvrditghalrgmtakdt..........
#=GC seq_cons                        ..........................................ps............................................................................................................................................................................................................hstp.au.slhhp+thasshulhhGGhlcuDsphW.Gsslsc.......p.ss....ph.usGp...N...I..alToAsLahLANlGcYlTAphphssscs......ssh..sltsAFVhFGNLDpSPhasolGKsp.lshGsFGGGGsaTsulo..paL..psu+VsNloLsYpscshNuslslFp....o....csppusFosuhFYupchstphshGhNsGYVaslsGAsNsuh.t...s...........h...........................
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