#=GF ID   DUF6336
#=GF AC   PF19862.3
#=GF DE   Family of unknown function (DUF6336)
#=GF AU   Williams LS;0000-0001-5551-8526
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Fragoso S;0000-0001-7018-3891
#=GF SE   Manual
#=GF GA   25.00 25.00;
#=GF TC   25.20 64.90;
#=GF NC   23.60 23.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   28894917
#=GF RT   Identification and characterization of the ficellomycin
#=GF RT   biosynthesis gene cluster from Streptomyces ficellus.
#=GF RA   Liu Y, Li M, Mu H, Song S, Zhang Y, Chen K, He X, Wang H, Dai Y,
#=GF RA   Lu F, Yan Z, Zhang H;
#=GF RL   Appl Microbiol Biotechnol. 2017;101:7589-7602.
#=GF DR   INTERPRO; IPR046299;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This entry represents a member of a biosynthetic gene cluster
#=GF CC   (BGC). This BGC (BGC0001593) is described by MIBiG as an example
#=GF CC   of the following biosynthetic class, NRP (non-ribosomal
#=GF CC   peptide), in  particular the ficellomycin biosynthetic gene
#=GF CC   cluster from  Streptomyces ficellus [1].
#=GF SQ   16
#=GS K4R8J9_STRDJ/9-136       AC K4R8J9.1
#=GS A0A2D3UKN2_STRC0/1-128   AC A0A2D3UKN2.1
#=GS B5HJE3_STRE2/1-102       AC B5HJE3.1
#=GS A0A0F5W0E4_9ACTN/8-134   AC A0A0F5W0E4.1
#=GS A0A6G4V8K5_9ACTN/1-126   AC A0A6G4V8K5.1
#=GS A0A7H8J2B2_9ACTN/1-128   AC A0A7H8J2B2.1
#=GS A0A846XDX8_9NOCA/11-138  AC A0A846XDX8.1
#=GS D9WQ19_9ACTN/8-135       AC D9WQ19.1
#=GS A0A429UF35_9ACTN/1-99    AC A0A429UF35.1
#=GS A0A505DI31_9ACTN/8-134   AC A0A505DI31.1
#=GS S3ZDJ1_9ACTN/1-128       AC S3ZDJ1.1
#=GS S4N1U9_9ACTN/1-112       AC S4N1U9.1
#=GS A0A2A4KBG6_9ACTN/11-138  AC A0A2A4KBG6.1
#=GS A0A542QI54_9ACTN/1-70    AC A0A542QI54.1
#=GS A0A2W6RLB7_9ACTN/8-135   AC A0A2W6RLB7.1
#=GS A0A7W7VA55_9ACTN/1-89    AC A0A7W7VA55.1
K4R8J9_STRDJ/9-136                  .VITPRLRLRDVLLRGSLFGLFAALLLAACLLFVGDHHDREEFFGVFGGLMLIFGAGFLVFGLLFWLLCRDDIRRFRDWGTITTQSASATLVGPAFVRIGLLGLIVGLAGVTIAGLVDQASYDSWIYGD.....
A0A2D3UKN2_STRC0/1-128              .MRLPRLRLEGVVVRGAAQGIAAVALLSVAMLFVTDHHDRETFLSVAAGLSAVSAGVGVVIGAFFWAVCSGDIRRRRDWRTVTGQTEGVTIMAPALVRTGVLALVLFPGALGLHHLVDNAGYNTWLYGE.....
B5HJE3_STRE2/1-102                  m-------------RVAAYGIAAIVVLAGAMLSVTDRHDRETFLSVVAGLSAVLAGVGIVVGAFFRAVCAGDIRRRRDRRTLAGRADAVTILAPALVRTGVLTVVLFTGA-------------------pwast
A0A0F5W0E4_9ACTN/8-134              .VRTPRLRLWDVVRRGALYGAGAAAVLCLGAFFVVDPDDRAALLGAVGFLALVTGGFFLAGGLFFWLCSRDDIRRWRDWRTVRSQSDAVTVFAPGCVRFAVAELVIAPAALGLADLIDRASYNSWL---ns...
A0A6G4V8K5_9ACTN/1-126              .--MPRLRFKGVVVRGAVQGIAAVALLCVGALFVADHHDRETFLAVVAGFSMVFAGVGIVVGGGFWAACSGDIRRLRDWRTITGQSESVTIVAPVFLRAGVLALVLFPGALGLYHLVDNAAYDSWLYGS.....
A0A7H8J2B2_9ACTN/1-128              .MHQPLLRFRDVALRGMLYGLAAIPLVGVGSLGVSDHHARMTFLAVTAGFAVIGGGVFTVTGLGFWAACGGDIRRCRDWRTITGQTESVTVAAPVLLRLGVLALVLFPGVLGLYHLVDNADYDSLIYGS.....
A0A846XDX8_9NOCA/11-138             v-LAPRLRLGGVLARGAAYGMGAAVCVIVAVFIIDEHDDRSDLLEATTFLGLLTGTVLLLTGLFLWACSSREILRWRDFSTTRAPNEVVSLAAPALVRVGVFLLAPVPVAFGLGELVASAGEGSWLWG-a....
D9WQ19_9ACTN/8-135                  .ITQPRLRVRDVLLRGALYGLASIVVLLIAMWRVGDHNDREESLAVVGGIALVFGGVFVVFGAFLWACCRGDIRRWRDFRSLTSQYEGATIMAPTMVRCGVTALVLAPAAMGLYGLVDEAAIGSWLYGS.....
A0A429UF35_9ACTN/1-99               m-----------------YGAGAAVCPTVTALVLRD-DARTDLLEAVAFLGLVAGAVSLLTGLFFWACCSGEVLRWRDLFRTSGPSEVIAVLAPCLVRVGVLLLVPVPVAAVL----------------grla.
A0A505DI31_9ACTN/8-134              .VMLPRLRPADVARRGVTFGLLGVVPLVVAALSIPGHSNRRDFLAVVSGVVGLFGAILLLIGAGFWWASAGDVRRVRDWRTLTGQAASVTVVGPLFLRSGLFLLVLGAAALGLYQLVAAAPYGSWLY--s....
S3ZDJ1_9ACTN/1-128                  .MLLPRLRLKGVLGRGALFGVLANFVPLVGMCVVTEHHDRETFLAVVSGLGLIAGGFLLLIGLFFWSACGSDVRRWRDLRTITGQTEGLTIMAPACVRAGVVGLLLFPGPYGLYHLVDGAAFGSWLYGS.....
S4N1U9_9ACTN/1-112                  m----------------TFGLLGVVPLVVAALSITDHSDRRDFLAVVGGVVGLFGAILLVIGAGFWWASAEDVRRMRDWRTLTGQAASVTVVGPLFLRSGLFLLVLGAAALGLYQLVAAAPYGSWLH--s....
A0A2A4KBG6_9ACTN/11-138             v-LEPRLRLGGVAVRGAAYGAGAAICVTVATFALGEHEDRVDLLDATAFLGLVTGSVLLVTGLFFWACSGGEVLRWRDFFTTRAPDEVVAIAAPSLVRVGLLLLVPVPVALGLGEIVASAARGSWLGG-a....
A0A542QI54_9ACTN/1-70               .----------------------------------------------------------MFGGLFWTAYGGDIRRWRDVRTITGQTGCVMIKAPVLVRAGVLALVLFPGALGLYHLVDNSAYDSWLYGS.....
A0A2W6RLB7_9ACTN/8-135              .VLLPRLRLRDVLLRGVLFGLGAVVVMTVAALCVRDHHDREEFLAVVGGLCLVCGGALLLIGLFFWSACSGDIRRWRDWRTVTGQFEAPTVVAPALVRLGTLALVVAPAALGLYDLVDQADHGSWLHG-r....
A0A7W7VA55_9ACTN/1-89               m----------------------------------------TFLAVAGGFAAAVAVVGILIGPFFWWACGGDIRRCRDWRTVRGQAGPVTVAAPVLLRIGVLALVLFPGAFGLYHLVDGAGYDSWLYGD.....
#=GC seq_cons                       ..h.PRLRhtsVhhRGshaGluAssslsVuhhhlsDHcDRpsFLuVsuGluhlhGulhllhGhFFWusCuGDIRRhRDaRTlTGQs-uVTlhAPshVRsGVLsLVLhPuAlGLacLVDsAuasSWLaG......
//