#=GF ID DUF6386
#=GF AC PF19923.3
#=GF DE Family of unknown function (DUF6386)
#=GF AU Williams LS;0000-0001-5551-8526
#=GF AU Finn RD;0000-0001-8626-2148
#=GF AU Fragoso S;0000-0001-7018-3891
#=GF SE Manual
#=GF GA 25.90 25.90;
#=GF TC 26.50 26.00;
#=GF NC 25.40 25.70;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF WK Domain_of_unknown_function
#=GF RN [1]
#=GF RM 27694801
#=GF RT Polyketide and nonribosomal peptide retro-biosynthesis and
#=GF RT global gene cluster matching.
#=GF RA Dejong CA, Chen GM, Li H, Johnston CW, Edwards MR, Rees PN,
#=GF RA Skinnider MA, Webster AL, Magarvey NA;
#=GF RL Nat Chem Biol. 2016;12:1007-1014.
#=GF DR INTERPRO; IPR045665;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This entry represents a member of a biosynthetic gene cluster
#=GF CC (BGC). This BGC (BGC0001796) is described by MIBiG as an example
#=GF CC of the following biosynthetic class, NRP (non-ribosomal
#=GF CC peptide), in particular the tauramamide biosynthetic gene
#=GF CC cluster from Brevibacillus laterosporus DSM 25 [1].
#=GF SQ 18
#=GS A0A366HID7_9BACT/1-143 AC A0A366HID7.1
#=GS A0A172ZLQ1_9BACL/9-155 AC A0A172ZLQ1.1
#=GS E3EFT2_PAEPS/2-150 AC E3EFT2.1
#=GS A0A240BNW6_SERFI/1-147 AC A0A240BNW6.1
#=GS A0A419HC18_9PSEU/8-139 AC A0A419HC18.1
#=GS A0A518AVS1_9BACT/1-132 AC A0A518AVS1.1
#=GS C0ARG3_9GAMM/1-105 AC C0ARG3.1
#=GS A0A7Z2W1V0_9BURK/1-133 AC A0A7Z2W1V0.1
#=GS A0A5C6B8K1_9BACT/7-154 AC A0A5C6B8K1.1
#=GS A0A1X7HD40_9BACL/1-151 AC A0A1X7HD40.1
#=GS A0A268SE28_9BACL/3-154 AC A0A268SE28.1
#=GS A0A2V1K2T9_9BURK/1-147 AC A0A2V1K2T9.1
#=GS A0A0M2WGU6_9BURK/1-147 AC A0A0M2WGU6.1
#=GS A0A1E3L672_9BACL/1-147 AC A0A1E3L672.1
#=GS A0A5J5G094_9GAMM/1-147 AC A0A5J5G094.1
#=GS A0A0X1T2L6_PSEAA/1-147 AC A0A0X1T2L6.1
#=GS A0A318JD22_9BURK/1-144 AC A0A318JD22.1
#=GS Q7N9I6_PHOLL/1-74 AC Q7N9I6.1
A0A366HID7_9BACT/1-143 ...mn----.LSFVTDTSTLCVFDLEALRHRLHDDADWW..SIPEDEVAE.VNLGNVAFLGLGKDGRFD..VRLV.....D.EVHNG-...........ICVMLKCPSGRMFIGAGEEVTGGELEPEAVR..GGGFYRVEPGTYVVHAALvVPNQIQLSLSRTV..N-----------spvnrflvpvs..............
A0A172ZLQ1_9BACL/9-155 ....t-NTS.FSFSTDTAALAIFDMQAIHHRITDTPDWW..TIPEDELGE.LNQGNIIVCHLPADGTYD..VQLV.....P.HLADTQ...........VRCHLHVPSGQIFIGAGEDITGGNLQPDDPTfvSGQIITLPPGNYELSVHL.NEYKIQISFIPAR..EHHNSRRDSIRL.........................
E3EFT2_PAEPS/2-150 mnmai---SpFQFTTDTATLCLFDTQALKHRLNDEPDWW..SIEADELGE.LNAGNAAFLNLGADGTYE..VVIT.....D.HIEQPT...........VRLFLKVPSGNIFIGAGEEATGGELEPDCVW..GGSFLSVQPGLYECLASRgENNRIYLSLKKGS..EGSNSFTSLVRL.........................
A0A240BNW6_SERFI/1-147 .....MNKT.FSFTTDTATLSVFDLVSLKHRVGDDADWW..SIPEDELDE.VNKGNVLFLNLGEDGQYT..VRVI.....D.DISEGY...........KSLFLNVPSGKVFVGAGEDTSGGDLEPDGSDymSGVFLILDIGSYEVRFKR.DSFDIAISFIKSS..KNKNEEIELIRI.........................
A0A419HC18_9PSEU/8-139 devsa----.-ALATDSGMWALWDPEAIE-RLADDDSWEadTLEDDELVElVSAGQIVPVNIGADGSYQfvLRVV.....D.DTTGGLtdrekqyvsdsSAPYLFVSSGSVCL--------SGLECVSAE..------------------.-------------..------------pvgdvielplppgryqatahlid..
A0A518AVS1_9BACT/1-132 .....MDRT.FKFFTDTATLAMFDPQQLEHRVDDDVDWW..CLDFAQLDE.IQSGKIALVSLGGDGVYQ..TRIT.....DdDLNPDErdya...aelvANLGINVTSGKLFIGPGECLPGGQSRFDDSDtqRGALCEINNGIYRVDV--.-------------..------------yai......................
C0ARG3_9GAMM/1-105 .....----.-----------------------------..---------.MNKGNIAFIGLGNDGFYT..INLC.....D.KIEDPD...........VRININCPSGKVFIGAGEDTTGGDLEPDDPKyrAGEIIFLPVGDYEISLKK.VSNILFISIIFSK..ENLNKFENVLRL.........................
A0A7Z2W1V0_9BURK/1-133 .....----.---------MCVFDIASLKHRLEDDADWW..SIPDAELAE.VNRGNVAFLNLGSDGKYS..FTFA.....E.EVQCPQ...........VEVNLRVPSGRLFAGAAEEVTAEAFEPEAAR..GGMFIDIQPGEYTLRVSR.DGNEISLSLHLAH.gSNRNEFDSLIRI.........................
A0A5C6B8K1_9BACT/7-154 iptes----.-SFRTDTATLAVFDPKRLEHRLHDSADWW..SIPGDEVTE.INAGNVLFVSTGTDGDYL..LNVYcepppD.NVLPLA...........LSALIRCDSGSLFFHAGEYVPAGDMMPDTTY..GGLQLEFKPGTYRVTV--.-------------..------------lhlvpyclevfvalanedaandfcd
A0A1X7HD40_9BACL/1-151 .....MQGT.FRFITDTATMCVYDLGELKHRLDDTSDWW..SISEDELAE.VNAGNCLFFNLGQDGVYE..VNWI.....EaDVGMEDgg......amtEVLYFRVSSGSVFVGAADDVTGDGLEPDHTC..EGVFIELEPGSYACMAQR.EGNQIRLALSRSE..TGTNRREDLIRI.........................
A0A268SE28_9BACL/3-154 .....MRGT.FQFVTGTATMCLFDLASLKHRVEEPPDWW..SIPEDELAE.VNAGNCLFFNLGADGMYE..VSWS.....V.DISHSTsav....pegaQVFYLQVPTGSVFLGAAEDVSGGELEPDESC..DGMILSLQPGNVACIVSR.EGNQISLKIQPGT..QGHNEQDSLIRI.........................
A0A2V1K2T9_9BURK/1-147 .....MDIS.FNIFTDTATLVVFDLASLRHRLSDTPDWW..SLPEDELDE.INQGNAVFLNLGQDGVYV..VEIV.....D.NLLDYS...........GSVYVRVPSGRIFVGAGEDVTGGDLEPDNTAavSGRLIEMAPGSYAVRFRR.DGDVISLSFVVSG..EFRNHLEGPVRL.........................
A0A0M2WGU6_9BURK/1-147 .mtps--TG.VKIVTGTATLCVFDPALLRHKLEDDCDWW..SIPSAELAA.VNAGQVAFFNVGDDGAYE..VALY.....A.ELAEPQ...........VVVHLSVVSGRVFIGAGEDVTGGDLEPDTAY..GGLFVDVPVGSYRVQARR.DGARISLAFVPDT..RSSNAFGDLVRI.........................
A0A1E3L672_9BACL/1-147 .....MLNT.IQVMTDTATLCIYDLQALKHRLEDTSDWW..SIPEDELLE.VNLGNVAFLNVGADGLYT..MQQV.....E.DIQQTS...........VQLWINVPSGQLYAGAAENVTGGELEPEDGD..SGQYITVEPGVYHLKIAR.NEQQIEFALLRTEhqQATNEFKDLIRI.........................
A0A5J5G094_9GAMM/1-147 .....MDIT.FPVATDTATLVIFDLQALKHRIADTADWW..SIEEDAIDE.MNNGNVIFLDLRADGAYR..VELV.....G.TLTNAD...........GSLSIHCPSGQVFIGAGEDTTGDDLEPDDSAciSGRFIDIAAGRYAVGFKR.DDNVIRLSFAPTQ..ESKNSLSEIVRL.........................
A0A0X1T2L6_PSEAA/1-147 .....MIAG.FSVVTDTATIAVFDLQAIKHRISDTSDWW..SIVEDEIYE.VNEGNIAFFGLGEDGKFN..IRIS.....D.SLNGED...........GLLNIYFPSGQVFIGAGEDTTGGDLQPDGSDaiQGAMLDFEPGTYQVKYKK.TNDAVEFSFERSD..TRKNSLTEAIKL.........................
A0A318JD22_9BURK/1-144 ....m--HT.FEFVTDTATMCVFDLACLKHRLEDDADWW..SVSSAEIQE.VNNGNVAFLNFKSDGKYF..VSIV.....D.TIDEPD...........VSVNLKLNSGRVFFGAAEEVSSDGLEPEALR..GGIFLEFPVGLYALHIKK.TGFSILVAIKISD..ISTNSFFSVVRI.........................
Q7N9I6_PHOLL/1-74 ....m----.-----------------------------..---------.------------------..----.....-.------...........---NIKSPSGKIFIGAGEDTTGGDLEPDDSEyiSGKKISLEKGNYLILLKK.NENNIQISFIKSQ..YFSNNLQEPIRL.........................
#=GC seq_cons ........s.hphhTDTATlslFDhtuL+HRlpDssDWW..SIs-DELsE.lNtGNlsFlsLGsDGtYp..lpls.....-.clppsp...........sslhlpVPSGplFlGAGE-lTGG-LEPDssp..uGhhlplpsGsYtlphp+.ssspIpluhhhup..ptpNphpphlRl.........................
//
