GenomeNet

Database: Pfam
Entry: Dec-1
LinkDB: Dec-1
Original site: Dec-1 
#=GF ID   Dec-1
#=GF AC   PF04624.17
#=GF DE   Dec-1 repeat
#=GF PI   DEC-1_REPEAT;
#=GF AU   Kerrison ND;0000-0002-1471-953X
#=GF SE   DOMO:DM04594;
#=GF GA   22.00 22.00;
#=GF TC   25.00 22.10;
#=GF NC   18.70 21.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Repeat
#=GF RN   [1]
#=GF RM   1699826
#=GF RT   Multiple proteins are produced from the dec-1 eggshell gene in
#=GF RT   Drosophila by alternative RNA splicing and proteolytic cleavage
#=GF RT   events. 
#=GF RA   Waring GL, Hawley RJ, Schoenfeld T; 
#=GF RL   Dev Biol 1990;142:1-12.
#=GF RN   [2]
#=GF RM   8350348
#=GF RT   Evolution of the dec-1 eggshell locus in Drosophila. II.
#=GF RT   Intraspecific DNA sequence analysis reveals length mutations in
#=GF RT   a repetitive region in D. melanogaster. 
#=GF RA   Andersson S, Lambertsson A; 
#=GF RL   J Mol Evol 1993;36:536-544.
#=GF DR   INTERPRO; IPR006718;
#=GF DR   SO; 0001068; polypeptide_repeat;
#=GF CC   The defective chorion-1 gene (dec-1) in Drosophila encodes
#=GF CC   follicle cell proteins necessary for proper eggshell assembly.
#=GF CC   Multiple products of the dec-1 gene are formed by alternative
#=GF CC   RNA splicing and proteolytic processing [1]. Cleavage products
#=GF CC   include S80 (80 kDa) which is incorporated into the eggshell,
#=GF CC   and further proteolysis of S80 gives S60 (60 kDa). This repeat
#=GF CC   is usually found in 12 copies in the central region of the
#=GF CC   protein. Its function is unknown.  Length polymorphisms of Dec-1
#=GF CC   have been observed in wild-type strains, and are caused by
#=GF CC   changes in the numbers of the first five repeats [2].
#=GF SQ   79
#=GS DEC12_DROME/652-681       AC P18170.2
#=GS DEC13_DROME/545-571       AC P18171.2
#=GS DEC11_DROME/733-759       AC P18169.2
#=GS A0A0Q9XHG4_DROMO/639-662  AC A0A0Q9XHG4.1
#=GS DEC12_DROME/733-759       AC P18170.2
#=GS DEC12_DROME/597-623       AC P18170.2
#=GS DEC13_DROME/519-545       AC P18171.2
#=GS B3MRA8_DROAN/556-577      AC B3MRA8.2
#=GS DEC13_DROME/733-759       AC P18171.2
#=GS DEC12_DROME/519-545       AC P18170.2
#=GS B4MAG1_DROVI/571-593      AC B4MAG1.2
#=GS DEC11_DROME/493-519       AC P18169.2
#=GS M9NEY9_DROME/733-759      AC M9NEY9.1
#=GS B4L6A5_DROMO/639-661      AC B4L6A5.2
#=GS B3MRA8_DROAN/642-666      AC B3MRA8.2
#=GS DEC11_DROME/545-571       AC P18169.2
#=GS B3MRA8_DROAN/689-714      AC B3MRA8.2
#=GS A0A0Q9XHG4_DROMO/549-575  AC A0A0Q9XHG4.1
#=GS DEC13_DROME/623-649       AC P18171.2
#=GS B4MAG1_DROVI/678-709      AC B4MAG1.2
#=GS M9NG31_DROME/580-606      AC M9NG31.1
#=GS DEC13_DROME/597-623       AC P18171.2
#=GS M9NG31_DROME/554-580      AC M9NG31.1
#=GS DEC12_DROME/571-597       AC P18170.2
#=GS M9NG31_DROME/476-502      AC M9NG31.1
#=GS A0A6P4EXT8_DRORH/663-689  AC A0A6P4EXT8.1
#=GS M9NEY9_DROME/545-571      AC M9NEY9.1
#=GS M9NEA7_DROME/476-502      AC M9NEA7.1
#=GS A0A6P4ETS0_DRORH/717-736  AC A0A6P4ETS0.1
#=GS B4IL40_DROSE/599-628      AC B4IL40.1
#=GS B3MRA8_DROAN/622-643      AC B3MRA8.2
#=GS DEC11_DROME/571-597       AC P18169.2
#=GS B4MAG1_DROVI/547-569      AC B4MAG1.2
#=GS DEC12_DROME/623-649       AC P18170.2
#=GS DEC13_DROME/493-519       AC P18171.2
#=GS B4L6A5_DROMO/549-575      AC B4L6A5.2
#=GS A0A0Q9WTZ3_DROWI/752-773  AC A0A0Q9WTZ3.1
#=GS B3MRA8_DROAN/591-622      AC B3MRA8.2
#=GS DEC12_DROME/545-571       AC P18170.2
#=GS B4IL40_DROSE/669-695      AC B4IL40.1
#=GS A0A6P4ETS0_DRORH/663-689  AC A0A6P4ETS0.1
#=GS DEC12_DROME/493-519       AC P18170.2
#=GS M9NEY9_DROME/519-545      AC M9NEY9.1
#=GS B4IL40_DROSE/518-544      AC B4IL40.1
#=GS M9NEY9_DROME/623-649      AC M9NEY9.1
#=GS B4L6A5_DROMO/576-603      AC B4L6A5.2
#=GS M9NG31_DROME/528-554      AC M9NG31.1
#=GS M9NG31_DROME/502-528      AC M9NG31.1
#=GS M9NEA7_DROME/528-554      AC M9NEA7.1
#=GS DEC11_DROME/597-623       AC P18169.2
#=GS M9NEY9_DROME/493-519      AC M9NEY9.1
#=GS DEC11_DROME/623-649       AC P18169.2
#=GS B4MAG1_DROVI/711-738      AC B4MAG1.2
#=GS B4IL40_DROSE/570-596      AC B4IL40.1
#=GS A0A6P4EXT8_DRORH/717-736  AC A0A6P4EXT8.1
#=GS DEC13_DROME/652-681       AC P18171.2
#=GS B4NCW6_DROWI/752-774      AC B4NCW6.2
#=GS M9NEA7_DROME/502-528      AC M9NEA7.1
#=GS B4IL40_DROSE/544-570      AC B4IL40.1
#=GS A0A6J2TYD7_DROLE/907-935  AC A0A6J2TYD7.1
#=GS M9NG31_DROME/606-632      AC M9NG31.1
#=GS B4MAG1_DROVI/594-618      AC B4MAG1.2
#=GS M9NEA7_DROME/580-606      AC M9NEA7.1
#=GS B4MAG1_DROVI/755-774      AC B4MAG1.2
#=GS M9NEA7_DROME/635-664      AC M9NEA7.1
#=GS M9NEY9_DROME/571-597      AC M9NEY9.1
#=GS DEC11_DROME/519-545       AC P18169.2
#=GS A0A0Q9XHG4_DROMO/576-603  AC A0A0Q9XHG4.1
#=GS B4MAG1_DROVI/620-644      AC B4MAG1.2
#=GS M9NEA7_DROME/554-580      AC M9NEA7.1
#=GS B4IL40_DROSE/492-518      AC B4IL40.1
#=GS M9NEA7_DROME/606-632      AC M9NEA7.1
#=GS M9NEY9_DROME/652-681      AC M9NEY9.1
#=GS M9NG31_DROME/716-742      AC M9NG31.1
#=GS M9NEA7_DROME/716-742      AC M9NEA7.1
#=GS DEC11_DROME/652-681       AC P18169.2
#=GS DEC13_DROME/571-597       AC P18171.2
#=GS M9NEY9_DROME/597-623      AC M9NEY9.1
#=GS M9NG31_DROME/635-664      AC M9NG31.1
DEC12_DROME/652-681                  .QQGLMMteqRQRQWSEDQA.KI..QQA....QQMAQQ.......
DEC13_DROME/545-571                  .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
DEC11_DROME/733-759                  .ENPQMM...QQRQWSEEQT.KI..EQA....QQMAQQ.......
A0A0Q9XHG4_DROMO/639-662             .ENAQMM...--RQWSEEQA.KA..QQQ....QQQM--r......
DEC12_DROME/733-759                  .ENPQMM...QQRQWSEEQT.KI..EQA....QQMAQQ.......
DEC12_DROME/597-623                  .QNPMMV...QQRQWSEEQA.KI..QQN....QQQIQQ.......
DEC13_DROME/519-545                  .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
B3MRA8_DROAN/556-577                 .QSPMMM...QQRQWSEEQT.KI..QQE....R-----.......
DEC13_DROME/733-759                  .ENPQMM...QQRQWSEEQT.KI..EQA....QQMAQQ.......
DEC12_DROME/519-545                  .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
B4MAG1_DROVI/571-593                 p-NPMMM...--RQWTEEQM.KA..HQQ....------ardr...
DEC11_DROME/493-519                  .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
M9NEY9_DROME/733-759                 .ENPQMM...QQRQWSEEQT.KI..EQA....QQMAQQ.......
B4L6A5_DROMO/639-661                 .ENAQMM...--RQWSEEQA.KA..QQQ....QQQM--.......
B3MRA8_DROAN/642-666                 .QNPTMM...QQRQWSEDQA.K-..-QQ....QHMMQQ.......
DEC11_DROME/545-571                  .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
B3MRA8_DROAN/689-714                 .QGPMMM...-QRQWAEEEA.KA..LQD....QQTMQQ.......
A0A0Q9XHG4_DROMO/549-575             .QNPMMM...--RQWAEGEA.KAkeQQQ....SQQMQQ.......
DEC13_DROME/623-649                  .QNPMMM...QQRQWSEEQA.KI..QHD....QQMAQQ.......
B4MAG1_DROVI/678-709                 .QNPMTM...--RQWTEDQA.KA..QRE....PQEFQQqmpmimq
M9NG31_DROME/580-606                 .QNPMMV...QQRQWSEEQA.KI..QQN....QQQIQQ.......
DEC13_DROME/597-623                  .QNPMMV...QQRQWSEEQA.KI..QQN....QQQIQQ.......
M9NG31_DROME/554-580                 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
DEC12_DROME/571-597                  .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
M9NG31_DROME/476-502                 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
A0A6P4EXT8_DRORH/663-689             .ENPQTM...QQRQWLEEQA.KI..QQQ....QQQVQQ.......
M9NEY9_DROME/545-571                 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
M9NEA7_DROME/476-502                 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
A0A6P4ETS0_DRORH/717-736             .QNPIMM...QQRQWSEDAQ.KV..QQ-....------.......
B4IL40_DROSE/599-628                 .QQGLMMteqRQRQWSEDQA.KI..QQA....QQMAQQ.......
B3MRA8_DROAN/622-643                 .QNNMMM..qQQRQWSEEQA.KI..QQN....------.......
DEC11_DROME/571-597                  .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
B4MAG1_DROVI/547-569                 .QNDMMM...--RQWTEDKA.KA..Q--....QQMMQQ.......
DEC12_DROME/623-649                  .QNPMMM...QQRQWSEEQA.KI..QHD....QQMAQQ.......
DEC13_DROME/493-519                  .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
B4L6A5_DROMO/549-575                 .QNPMMM...--RQWAEGEA.KAkeQQQ....SQQMQQ.......
A0A0Q9WTZ3_DROWI/752-773             .QNPMMM...QQRQMAEEQA.KI..QQI....Q-----.......
B3MRA8_DROAN/591-622                 .QNNMMM..qQQRQWSEEQA.KI..QQEeqakQQAIQQ.......
DEC12_DROME/545-571                  .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
B4IL40_DROSE/669-695                 .ENPQMM...QQRQWSEEQT.KI..EQA....QQMAQQ.......
A0A6P4ETS0_DRORH/663-689             .ENPQTM...QQRQWLEEQA.KI..QQQ....QQQVQQ.......
DEC12_DROME/493-519                  .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
M9NEY9_DROME/519-545                 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
B4IL40_DROSE/518-544                 .QNPMMM...QQRQWSEEQA.KI..QQN....PQQIQQ.......
M9NEY9_DROME/623-649                 .QNPMMM...QQRQWSEEQA.KI..QHD....QQMAQQ.......
B4L6A5_DROMO/576-603                 .QNPMMM...--RQWAEGEA.KAkeQQQ...sQQMLQQ.......
M9NG31_DROME/528-554                 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
M9NG31_DROME/502-528                 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
M9NEA7_DROME/528-554                 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
DEC11_DROME/597-623                  .QNPMMV...QQRQWSEEQA.KI..QQN....QQQIQQ.......
M9NEY9_DROME/493-519                 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
DEC11_DROME/623-649                  .QNPMMM...QQRQWSEEQA.KI..QHD....QQMAQQ.......
B4MAG1_DROVI/711-738                 .QNPMMM...--RQWTEDQA.KA..QQQa.kaQQEMQQ.......
B4IL40_DROSE/570-596                 .QNPMMM...QQRQWAEDQA.KV..QHD....QQMAQQ.......
A0A6P4EXT8_DRORH/717-736             .QNPIMM...QQRQWSEDAQ.KV..QQ-....------.......
DEC13_DROME/652-681                  .QQGLMMteqRQRQWSEDQA.KI..QQA....QQMAQQ.......
B4NCW6_DROWI/752-774                 .QNPMMM...QQRQMAEEQA.KI..QQI....Q-----m......
M9NEA7_DROME/502-528                 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
B4IL40_DROSE/544-570                 .QNPMMM...QQRQWTEDQA.KI..QQN....QQQIQQ.......
A0A6J2TYD7_DROLE/907-935             .ENPMLM...QQRQWAEGQAvKA..LHK...qRQQMQQ.......
M9NG31_DROME/606-632                 .QNPMMM...QQRQWSEEQA.KI..QHD....QQMAQQ.......
B4MAG1_DROVI/594-618                 .QNSMMM...--RQWTEDQA.KA..QQQ....NTMMMQ.......
M9NEA7_DROME/580-606                 .QNPMMV...QQRQWSEEQA.KI..QQN....QQQIQQ.......
B4MAG1_DROVI/755-774                 .------...QQRQWTEEQA.KA..QQP....QQM---se.....
M9NEA7_DROME/635-664                 .QQGLMMteqRQRQWSEDQA.KI..QQA....QQMAQQ.......
M9NEY9_DROME/571-597                 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
DEC11_DROME/519-545                  .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
A0A0Q9XHG4_DROMO/576-603             .QNPMMM...--RQWAEGEA.KAkeQQQ...sQQMLQQ.......
B4MAG1_DROVI/620-644                 .QNPMMM...--RQWTEDQA.KA..QQQa.kdQQM---.......
M9NEA7_DROME/554-580                 .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
B4IL40_DROSE/492-518                 .QNPMMM...EQRQWSEEQA.KI..QQN....QQQIQQ.......
M9NEA7_DROME/606-632                 .QNPMMM...QQRQWSEEQA.KI..QHD....QQMAQQ.......
M9NEY9_DROME/652-681                 .QQGLMMteqRQRQWSEDQA.KI..QQA....QQMAQQ.......
M9NG31_DROME/716-742                 .ENPQMM...QQRQWSEEQT.KI..EQA....QQMAQQ.......
M9NEA7_DROME/716-742                 .ENPQMM...QQRQWSEEQT.KI..EQA....QQMAQQ.......
DEC11_DROME/652-681                  .QQGLMMteqRQRQWSEDQA.KI..QQA....QQMAQQ.......
DEC13_DROME/571-597                  .QNPMMM...QQRQWSEEQA.KI..QQN....QQQIQQ.......
M9NEY9_DROME/597-623                 .QNPMMV...QQRQWSEEQA.KI..QQN....QQQIQQ.......
M9NG31_DROME/635-664                 .QQGLMMteqRQRQWSEDQA.KI..QQA....QQMAQQ.......
#=GC seq_cons                        .QNPMMM...QQRQWSEEQA.KI..QQs....QQ.hQQ.......
//
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