#=GF ID   Dip
#=GF AC   PF17679.5
#=GF DE   gp37/Dip protein
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Q8SDC5
#=GF GA   27.00 27.00;
#=GF TC   33.90 563.40;
#=GF NC   23.80 19.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   27447594
#=GF RT   Structural elucidation of a novel mechanism for the
#=GF RT   bacteriophage-based inhibition of the RNA degradosome.
#=GF RA   Van den Bossche A, Hardwick SW, Ceyssens PJ, Hendrix H, Voet M,
#=GF RA   Dendooven T, Bandyra KJ, De Maeyer M, Aertsen A, Noben JP, Luisi
#=GF RA   BF, Lavigne R;
#=GF RL   Elife. 2016; [Epub ahead of print]
#=GF DR   INTERPRO; IPR040860;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This protein is found in the giant phage phi KZ. This protein
#=GF CC   has been shown to bind to RNAse E of the host P. aeruginosa and
#=GF CC   to inhibit the RNA degradation machinery of the bacterium [1].
#=GF SQ   2
#=GS A0A2D1GRE7_9CAUD/1-273  AC A0A2D1GRE7.1
#=GS Q8SDC5_BPDPK/1-273      AC Q8SDC5.1
A0A2D1GRE7_9CAUD/1-273             MTQFNITWEEQRQSLSKLDGSFHPHKLEDITIQWVYDPVDNSVFVRCATMGNYDTYHTFKPQSSPDNAMVREYVLSRIIAENLKYIDNLYLAAGVVIFGDDEYIRDGNVIGIHIADCVGYDKLILPVIEFMPGVHIDDISDELIKSSSYQGIFKTDNLEEFEFLVDKKNAVNVQNLILAYTDYFTNKLAFKEPTEPAVEMYQFIDRTEVYFSFEGCHPDVEEVLFTIKIVRYNQPLNSTAMQVFLKNPLLPHIRTVVRQDLPAKFVGGVLFNF
Q8SDC5_BPDPK/1-273                 MTQFNITWEEQLQALSKLDGLHHPHKLEDISVHWVFNPVDISVFVTCATMSSHNTHYTFKPQSSPDDAMVREYVLSRIIADNLKYVDNLYLAAGAVICGNDEYISDGNVVGIHIADGVGGNKLILPVIEFMPGVHVDDISDKLIKSSSYQGIFKTDNLEEFEFLVDKKNANNVKELILAYTDYFANKLAFKDPAEPAVEMYQFIDRTEVYFSFEGCHPDVEEVLFTIKIVRYNQPLNSTAMQVFLKNPLLSHIRTVVRQDLPAKFVGGVLFNF
#=GC seq_cons                      MTQFNITWEEQhQuLSKLDG.aHPHKLEDIolpWVasPVD.SVFVpCATMusasTaaTFKPQSSPDsAMVREYVLSRIIA-NLKYlDNLYLAAGsVIhGsDEYIpDGNVlGIHIADsVGhsKLILPVIEFMPGVHlDDISDcLIKSSSYQGIFKTDNLEEFEFLVDKKNAsNVppLILAYTDYFsNKLAFK-PsEPAVEMYQFIDRTEVYFSFEGCHPDVEEVLFTIKIVRYNQPLNSTAMQVFLKNPLLsHIRTVVRQDLPAKFVGGVLFNF
//