#=GF ID   DnaGprimase_HBD
#=GF AC   PF16730.9
#=GF DE   DnaG-primase C-terminal, helicase-binding domain
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   pdb_4ehs
#=GF GA   25.90 25.90;
#=GF TC   26.50 29.10;
#=GF NC   25.70 25.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   23585534
#=GF RT   Crystal structure and mode of helicase binding of the C-terminal
#=GF RT   domain of primase from Helicobacter pylori.
#=GF RA   Abdul Rehman SA, Verma V, Mazumder M, Dhar SK, Gourinath S;
#=GF RL   J Bacteriol. 2013;195:2826-2838.
#=GF DR   INTERPRO; IPR031988;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   DnaG-primase_C is the C-terminal of a set of eubacterial DnaG
#=GF CC   primases that are a single-stranded DNA (ssDNA)-dependent RNA
#=GF CC   polymerase responsible for the synthesis of oligonucleotide
#=GF CC   primers needed for the replication of DNA. It interacts with
#=GF CC   helicase at the replication fork [1].
#=GF SQ   69
#=GS A0A2D3WS12_9PROT/428-546  AC A0A2D3WS12.1
#=GS A0A329ZKR4_9HELI/426-545  AC A0A329ZKR4.1
#=GS D1B4H3_SULD5/428-545      AC D1B4H3.1
#=GS C6RDX9_9PROT/439-551      AC C6RDX9.1
#=GS A0A2D3WI48_9PROT/429-546  AC A0A2D3WI48.1
#=GS A0A6G5R6P1_9PROT/437-547  AC A0A6G5R6P1.1
#=GS F8KRH5_HELBC/21-138       AC F8KRH5.1
#=GS E4TWR6_SULKY/427-545      AC E4TWR6.1
#=GS Q30UM7_SULDN/429-547      AC Q30UM7.1
#=GS A6QCI7_SULNB/428-546      AC A6QCI7.1
#=GS A0A347VPD4_9HELI/435-552  AC A0A347VPD4.1
#=GS D5V148_ARCNC/426-542      AC D5V148.1
#=GS A0A4U8UC08_9HELI/433-550  AC A0A4U8UC08.1
#=GS D3UI23_HELM1/449-565      AC D3UI23.1
#=GS A0A2D3W988_9PROT/1-84     AC A0A2D3W988.1
#=GS Q7M838_WOLSU/430-547      AC Q7M838.1
#=GS A0A329ZUL6_9HELI/426-542  AC A0A329ZUL6.1
#=GS A0A2W6NIB8_9HELI/434-551  AC A0A2W6NIB8.1
#=GS I2K630_9PROT/429-547      AC I2K630.1
#=GS A0A099U090_9HELI/432-546  AC A0A099U090.1
#=GS A0A1P8KQW1_9PROT/425-541  AC A0A1P8KQW1.1
#=GS A0A7S7M075_9PROT/429-547  AC A0A7S7M075.1
#=GS Q7VGW9_HELHP/394-512      AC Q7VGW9.1
#=GS V8CAR7_9HELI/470-580      AC V8CAR7.1
#=GS I7GU33_9HELI/426-544      AC I7GU33.1
#=GS A0A1I5UBU9_9PROT/443-559  AC A0A1I5UBU9.1
#=GS A0A3D8II49_9HELI/422-539  AC A0A3D8II49.1
#=GS A0A381DKI7_9PROT/434-547  AC A0A381DKI7.1
#=GS A0A2D3VX29_9PROT/443-561  AC A0A2D3VX29.1
#=GS A0A3D8IPS8_9HELI/430-547  AC A0A3D8IPS8.1
#=GS T1CW08_9HELI/426-532      AC T1CW08.1
#=GS A7H183_CAMC5/437-553      AC A7H183.1
#=GS A6Q1G7_NITSB/435-551      AC A6Q1G7.1
#=GS A0A2T4CPP8_9PROT/429-547  AC A0A2T4CPP8.1
#=GS A0A7H9CIJ1_9PROT/453-565  AC A0A7H9CIJ1.1
#=GS DNAG_HELPY/443-558        AC P56064.1
#=GS A0A2P8R3M1_9PROT/434-546  AC A0A2P8R3M1.1
#=GS A0A4Q0XQ98_9PROT/426-542  AC A0A4Q0XQ98.1
#=GS A0A4U8UFB9_9HELI/408-505  AC A0A4U8UFB9.1
#=GS A0A3D8JAK5_9HELI/436-551  AC A0A3D8JAK5.1
#=GS A0A5P8P3N2_9PROT/430-542  AC A0A5P8P3N2.1
#=GS A0A363D394_9PROT/425-541  AC A0A363D394.1
#=GS A0A345IZH6_9PROT/425-541  AC A0A345IZH6.1
#=GS V8CIG6_9HELI/431-542      AC V8CIG6.1
#=GS C5ZXC6_9HELI/433-550      AC C5ZXC6.1
#=GS A0A4V6I5X0_9HELI/430-546  AC A0A4V6I5X0.1
#=GS A0A268T951_9HELI/433-549  AC A0A268T951.1
#=GS A0A3D8IX73_9HELI/429-543  AC A0A3D8IX73.1
#=GS A0A3D8HTC3_9HELI/444-563  AC A0A3D8HTC3.1
#=GS B9LAC3_NAUPA/419-535      AC B9LAC3.1
#=GS A0A6M0L052_9PROT/428-546  AC A0A6M0L052.1
#=GS A8EV86_ALIB4/425-541      AC A8EV86.1
#=GS A0A345J733_9PROT/426-542  AC A0A345J733.1
#=GS E0UP52_SULAO/435-553      AC E0UP52.1
#=GS A0A2D3W887_9PROT/428-544  AC A0A2D3W887.1
#=GS E6X3A2_NITSE/431-549      AC E6X3A2.1
#=GS H5VEY4_HELBI/34-151       AC H5VEY4.1
#=GS A0A3G9GTJ4_9PROT/428-544  AC A0A3G9GTJ4.1
#=GS A0A4Q0XZN6_9PROT/425-541  AC A0A4Q0XZN6.1
#=GS A0A1B1U605_9HELI/421-535  AC A0A1B1U605.1
#=GS A0A2A2GTZ4_9HELI/430-553  AC A0A2A2GTZ4.1
#=GS A0A7M3V901_9PROT/433-551  AC A0A7M3V901.1
#=GS A0A7L8V3F9_9PROT/429-545  AC A0A7L8V3F9.1
#=GS B6BH19_SULGG/431-549      AC B6BH19.1
#=GS A0A268U006_9HELI/437-552  AC A0A268U006.1
#=GS E7G310_9HELI/459-579      AC E7G310.1
#=GS A0A091ANE2_9PROT/427-545  AC A0A091ANE2.1
#=GS A0A1B8J998_9HELI/461-567  AC A0A1B8J998.1
#=GS T0JQ25_9PROT/431-549      AC T0JQ25.1
A0A2D3WS12_9PROT/428-546             ..DVAQLSILKTLLEKPNLIDDVLNVVDVNMFGKYTELFRALI...KG.E......KE..H..PY.LMGLSINES.LQVMS...ESELKDILRNFLIKHYDVRLKHIVA.DATIPFAKKSFLIRKIKTDIIpRLKRGELVA......
A0A329ZKR4_9HELI/426-545             ..DIAECTLIFTLIENPEWIDIAAEYIDSSVFMHYAKEYILLL...QG.Kk....aQE..D..KD.LRSIWLNSN.LKAIR..nIKEFKEHLRILITQAYKKDLQMINK.-LNTDPKQKLETLATIRNKLT.KLLQGELI-s.....
D1B4H3_SULD5/428-545                 ..DMLELTIIKTILSEPSLIDTVLDTIDSSMFKTHQEEFMLLL...EN.Q......RE..H..PK.LRRIELWED.IKIYD...EKELIASMISFLYHYYSEKFQEIRS.ARELSYEKKQFLIRKIQEKMM.KLKQGELVP......
C6RDX9_9PROT/439-551                 ..DPLEIQILKTMIENESLKKFILENLKPDYFARHRAVYEAIT...AGaD......AN..D..PS.VREIIFEKY.EAFKN...EEEILQNLKFFKTRFYKNLYKKYSA.-SQISLEEKQPILKKINEILK.ELKK-----......
A0A2D3WI48_9PROT/429-546             ..DMLELTIIKTILSQPGLIDTVLDTIDHAMFKTHQEEFLLLL...EN.R......LD..H..PK.LRRILLWDD.VKVYD...ENELIASMAAFLYHFYNEKFQAIKT.SKTLSYEQKQFMIRKIQEKLM.KLKKGELVP......
A0A6G5R6P1_9PROT/437-547             ..DKLELELLKTLAEANGLSDMILDLVKKEYFTHHGEIFEAIL...RR.S......PE..D..EAiLREISLEDV.DIMQS...EEQILEAVKILKIRFYENMRREYLS.SNR---SDKIEILKKIGMILE.KLKR-----......
F8KRH5_HELBC/21-138                  ..DPLEEVLIKYMALDHALIQNALDFVKVESFRHCQEEFKALC...AG.Q......FD..K..AC.LVAIMLDDR.LPIEP...-HGFKDNLVKLIKRHCEWQITQIHTlYTHLDLSERIALMNEWKKKRY.LCEQGELV-r.....
E4TWR6_SULKY/427-545                 ..DIWELSFIKTLLERPHIADTLLDFIDASLLQYHVQEFESAL...QG.R......ND..D..PR.LSALMMDDR.IRTFE..gDEGLRAELITFLSAHYNRELKKVTT.QNTVSFDQKSYLIRQYRDKIE.RLKRGELVP......
Q30UM7_SULDN/429-547                 ..DMWELTLIKTVLEHPEFIDQILDVLDPSLLKFHSSELSLAL...RG.E......FS..H..PQ.LMAIAVDEQ.IKALN..sEDALRAELVSFLMKHYEREYKKVNV.LSDITFEEKAFYIRKFKGKIE.LLKRGELVA......
A6QCI7_SULNB/428-546                 ..DVAQLSILKTLLEKPELIDSVLDVIDVNMFGGYAAMFSALI...SG.E......KE..Y..PH.LMGLAVDDT.FQVMD...EAELQGVLRNFLIKHYDMKLKHIVA.DQTIPFEKKSFLIRKIKTDIIpRLKRGELVA......
A0A347VPD4_9HELI/435-552             .n-FAEETILINMLENKEHFFFALDYLSEKYFRLYADEFSLIT...QG.K......SE..D..SK.IYALRFKSN.AHLLN...NEDFREQVRLFILQYAQNALRDITQ.DSNLNAEAKLALITQMKHNIL.RLQNGEIL-s.....
D5V148_ARCNC/426-542                 ..DIGELCIIKAILNDKNRLSSVLDIIDASMFDYHKNEFEILL...-T.N......ID..D..ER.LNSVLLNER.LEDYD...DERLNAELLILLGKFYSNKLNEVLY.DKNYTFNEKSSLIRKIRDNIS.MLKKGKLIT......
A0A4U8UC08_9HELI/433-550             tl--VEKIIIKSVLEDMDLLEYVMNYLESSMFFSQREAYEKLL...KK.D......LE..D..SQ.LIGILLDER.IKTQN...KEMLKRQMIMILYKHYNERRKILIK.DSTLSLREKSFLLRKLQQYLE.NLKKGDLI-v.....
D3UI23_HELM1/449-565                 sq--LEELIIRYILETPSLLDLALQYIDAEIFQHQKQAFCALL...AK.N......LD..H..PS.LIGIRINPK.LITTP...-HGFRNELRLLILRYNTSLLNSIQK.ERALSFEQKSFRIRKIKNHIL.KLKQGELIA......
A0A2D3W988_9PROT/1-84                ..----------------------------MFQKHKEEFEYLL...SG.Q......ID..-..-R.LTSVLARSE.LKTLT...LEEYKSQLCMFLYKYYQNQYLLVIN.----DFQKKANISKEFKIIEQ.RLKSGN---pik...
Q7M838_WOLSU/430-547                 ..ELAEASLIKTILEQPRLLEFVLEYLDSEVFGVHQAEFELLK...LG.E......FE..H..PK.LLRILLQER.IHPLE...ESVLKEQLRLMLRHFYSKKLKEIAA.NKSLDFKIRAFWLGKIRVHLE.KLEKGGLVP......
A0A329ZUL6_9HELI/426-542             dp--VLANILKMIIQDIALLDSLLEYVDTPVFQGYEEEFELLK...QN.N......LE..A..AP.ILKIMLDEQ.IVGMD...KANLKKQVCMILDRYYRKQLVEVAH.QKTLSSERRSFLLDKIRLKLQ.ELQKGEL--p.....
A0A2W6NIB8_9HELI/434-551             .t-LAEKIIIKSILEDSSLMDLALNYLQEDMFISQKEAFVALM...HN.N......LS..H..SL.LVGILLDNK.ILSLP...KEGLKKQIIMLLYRYYEGQKNALSN.QTKMTLREKSYLLRKYQNYLE.KLKKGELV-i.....
I2K630_9PROT/429-547                 ..DVAHLSILKTLIENPNLIDNVLSVMDIEMFGTYAELFTALI...NG.E......SE..H..PG.LVGLSVDDS.LEVMN...EEELNSVLRNFLIKHYDLKLKSIAS.SQQIPFEKKSFLIRKIRTDIIpRLKKGELVA......
A0A099U090_9HELI/432-546             .n-ISEANILVSMLDNEENFYLGMQFLDIKHFMTYREEFSMIS...NG.I......RE..H..DK.IMTLRFKSN.ASFSN...-KEFAYELRIFLLAYAKNLVNNISR.DSNLIGMARIEAIGKLRNAIR.ILE------lerr..
A0A1P8KQW1_9PROT/425-541             ..DIAELCIIKSILEKPSRLDSVLDIVDSSMFEAHKYEFELLL...-N.D......IT..N..IS.LNSITLNEK.LENYD...DERLNKELLTLLYKFYTNKLTSTKF.NDKLSLKEKSLNLRKIQDALR.QLKSGKLV-s.....
A0A7S7M075_9PROT/429-547             ..DMWELSLIKTVLEKPELINQILDVLDPSLLQFHSFELALAL...SG.K......FD..E..PN.LMAILVDDK.IKSLK..dEEALKAELIAFLTKHYERELKKVNM.QSAVSFEEKAFYIRKFRGKIA.TLKKGELVA......
Q7VGW9_HELHP/394-512                 ..DFAESVLIKSFLEKPNLIDFAIEYIDISLFKYKKIEFGLVT...NQ.C......YD..D..PR.LLAISLNDN.IKPLP..dLPSLKEHLRLFVTQAYSQLLGQIPH.SNEMSLRRKSEIIKELKTKIL.TLKKGELLP......
V8CAR7_9HELI/470-580                 ..DRLERLILRYMLENESLLNRALDFIDVRIFVDYREAFEALC...AD.N......KN..H..PL.LLGIALDPLpLRNDD..eGKGFEEELKYFIRRYLERELKLAT-.--------DISLITRLRSKIA.KLNKGEL--qt....
I7GU33_9HELI/426-544                 ..EIAESVLVKTLLEKPRWIDFTLEYIDISLFAYKREEFAKLL...QQ.E......VE..H..PL.LIAIAINEK.IKPLN..dLPSLKEHLRLFIIQAYTQFLSQIPR.FEAMSLQEKGTLIKEVKTKIL.QLKKGELLP......
A0A1I5UBU9_9PROT/443-559             ..DVAEESIIKTLLKIPSLTDMVLDTMDSSMFKIHREAFEALI...RG.E......-E..H..ED.LLRIDLDDT.IVIYQ...EDELKKQLVYFLRRYYQKALDNIKN.NDTLPFEKKIFFIRKYQDYIN.KLKRGELV-q.....
A0A3D8II49_9HELI/422-539             ..EIVEEVLIKSMLDDSSLFELSLEYLNPSIFSNKKEAYLALL...RG.D......LK..H..NE.LIGININND.IPSLS...MNDFKEQMRIFIMNFYKKKLILIRQ.NKSLSYDEKISFARDIQNKIN.ILQSGILV-r.....
A0A381DKI7_9PROT/434-547             ..DYLELSILKSAMSFSNLKRILVELCEKSYFRVHKKEYGAVVygaKN.E......ED..E..GV.LRELDFDES.VEIYK..nEDTFLQAIKMLKIKYYEGMLEAMKN.---ANIENKLEKIEKINSKIM.KLK------g.....
A0A2D3VX29_9PROT/443-561             ..DMWELSLVKTVLEYPQFIDQMLDVLDPSLLAFHAREFSQAL...HG.D......KN..A..PE.LMAILVDES.INSLQ..dEASLKQELLTFLTKYYEKELKKINT.QASISFEEKAFLIRKLRGKIA.ALRKGELVA......
A0A3D8IPS8_9HELI/430-547             ..DYAEENILINMLKSSEYFFFALNFLDKKHFRKYAHEFELIT...QG.K......QH..D..EL.IIALQFKSN.VQNLQ...QVEFEEQIRIFLLKYAKETLQNTLN.NTTLNGNEKIQNIIHLRNAIQ.KLEKGEIL-t.....
T1CW08_9HELI/426-532                 ..DRLERIILRYMLEDERFLEKGFDFLDSKVFKDYKNAFLALC...QN.N......KD..N..PQ.LIGIMLDP-.LPIKH...-DGFEAELRIFLLRYFEEELKKEQN.-----F----QNILQLKQKIL.KLKQGEL--qp....
A7H183_CAMC5/437-553                 ..DILEISILKSMLFNENFAAIVLDTIDEKYFLHHKEGFRAIL...SN.S......SEsdE..IL.LREIELDES.AMVIG..dEKKLLSAIANLKIKFYENLQLHIRS.SSDSDKIE---KLQKIAAIIN.NL-------kfqirn
A6Q1G7_NITSB/435-551                 ..DPKELSIIKTMLTKPHTVDIILDIIDASHFTYHQEEFELTL...QN.R......VD..H..PK.IRSILLNED.ILVFE...EEHIRSELLVFLIKYYEQKIQEVVK.-GDFPFNQKSFLIRKYKENIK.RLKEGELI-i.....
A0A2T4CPP8_9PROT/429-547             ..DVAQLSILKTLIEHPTFIDNVLAVIDVNMFGEYAGLFSALI...NG.E......YE..N..PG.LVGLSVDEN.FEVMT...EEELNKALLQILTLHYMARLRTLPS.DTTMSADKKMFLLRKIKMDILpRLKKGELVA......
A0A7H9CIJ1_9PROT/453-565             ..DTLKLSILKNMLLDENLLNYAKTKLIAAMFGQESEHFNAVI...NN.P......ND..EnnEL.IRALKMDES.LEQYD...FSDFKRAINRLLMLYFERKIAEILA.STDANKSQKIKDLRK---AIA.---------iikne.
DNAG_HELPY/443-558                   ..EFLEKLVIRYLLEDRSLLDLAVGYIHSGVFLHKKQEFDALC...QE.K......LD..D..PK.LVALLLDAN.LPLKK...-GGFEKELRLLILRYFERQLKEIPK.-SSLPFSEKMICLKKARQAIM.KLKQGELVA......
A0A2P8R3M1_9PROT/434-546             ..DYLELSILKTLLVDNRFYKSGYDMCNEEMFARHFDIFRLIK...LK.K......YD..D..EQ.IRELLIDED.IEVIN..sQSQFFKGIGILKEKYYKILLEDIKH.SNDP---QKMEKIMKIQNALR.KL-------rgvk..
A0A4Q0XQ98_9PROT/426-542             ..DILELSIIKSIADNPTRLEMVLDSIDASMFEFHKEEFELLL...-N.D......PQ..N..PR.LTGILLNEQ.IKIYD...DAQLEKELRFILIKFYEKRLSQVKY.ETHLEHNEKKVLIFKIRDNIA.QLRKGKLI-s.....
A0A4U8UFB9_9HELI/408-505             ts--LEQSLLKTLLLDESLIEITLNCLDNEDLGEYAQDYESFV...FK.K......VL..T..QK.ARDILLDES.ISTIP...FAKFKHCVLELKRRYYKLQIEKAKA.KRDID----------------.---------slily.
A0A3D8JAK5_9HELI/436-551             ..DLLEELVIKYMIEDNKLLDFALDYIDEKVFKNQKEAFRALL...NQ.N......FE..H..QK.LIGISLNPQ.LIVTE...-NGFKKELILLILRYNYTLLEEIQQ.-STLSFNEKSHQIRKIKNNIL.KLKKGELIA......
A0A5P8P3N2_9PROT/430-542             ..DMWELSLIKTLLEKPHMLTQVLDVLDPSLLQFHQNEFSLLI...SN.Q......TE..H..PS.IMAISVDES.IKVIQ..nEDELQKELNTFLSKHYNRELKKINI.RQDISYEQKGFEIRRLRKLIS.KLK------......
A0A363D394_9PROT/425-541             ..DIAELCIIKSILEKPKRLDSVLDIVDSSMFETHKNEFELLL...-T.D......IE..N..IS.LNSIVLNEK.LENYD...DERLNQELLTLVYKFYTNKLTAISY.DNTLDFKQKANLIRKIKDNIY.QLKLGKLV-s.....
A0A345IZH6_9PROT/425-541             ..DIAELCIIRAILENPKRLDMVLDIVDISMFEYHKNEFELLI...-N.E......PT..N..TI.LNGILLNDK.LEVYD...EQRLKEELIVLLYTFYTKKLTSLKY.DQTLNLREKGFKLRKVQDNLR.QLKQGKLV-s.....
V8CIG6_9HELI/431-542                 ..DKLERLILRYMLEDEALLNQALLYIDRSIFTDYQDAFDALC...AN.N......LS..H..PK.LLGIALDP-.LPLCE...-GGFEAELRIFILRFLESKLKQTKDiAQITQLRAKILSLKATKTTER.KL-------qp....
C5ZXC6_9HELI/433-550                 ..DLAEKAIIKSVLEDMNLLEFVMDFLEPTMFFSQKEAYLKLL...KG.E......LE..D..PS.LIRILLDNK.VKAQD...KEKLKQQMIMILYQYYEEQKQKVIN.EKQLSLREKSFLIRKYQKYLD.NLKKGDLI-v.....
A0A4V6I5X0_9HELI/430-546             .n-FAEESILYNMLEHKEHFYLAINFLTKEHFQTYYDEFQLIC...NQ.D......YD..N..DR.IYALRFKTK.AKILN...DEEFKEQLRIFLLQYAQDMLPKIAM.-SSIESNLKFQQIKALHENIA.KLKGGELV-s.....
A0A268T951_9HELI/433-549             ..DKLESLIIKYILEDRSLLDKAVEYIDESVFQYRAKEFDAIC...RG.D......FE..D..PA.LIGIALDEG.LLLCD...-GGFEAELLTLILRHKQNQLEKIIH.HHSFSFEEKSFKIRKIKDEII.RLKKGELIA......
A0A3D8IX73_9HELI/429-543             .n-PLEVMIITTMYEKEELLEWAIEYLEKDHFLECKSEYEALL...AN.R......KE..D..SR.LQALLSSAN.ARVAH...EEEFKKQVLLKVCKENENKIQKIIS.SNELDYDTKLKAITQLQQKIQ.QIKK-----el....
A0A3D8HTC3_9HELI/444-563             ..DIAESVLIYTLLEHRDWLDTALEYIDSDVFLHYKKEFELLLs.gQN.A......QE..N..EN.LRALWINEN.LKSLE..tIEELRAHLRILITQAYKRDLRAVPN.-LGLDSKQKLESLATIKQKIS.QLQKGELI-s.....
B9LAC3_NAUPA/419-535                 ..EIAEASIIKTLYENPHLMDEIVEYLSPDMFKTHRHELSLVY...QE.K......FD..D..PA.LLDIVLRED.VLCLN...MEALKKQIIKLLIPYYQQKVLELKT.-SNLPTDEKMHKLKILNYKIL.QLKKGELV-e.....
A0A6M0L052_9PROT/428-546             ..DVGQLSIIKTLHEKKKLINEVISVVDSSMFGSYASLFDAVI...KE.E......QG..N..SN.LTGLMLDEN.IKVMD...EDELKKALSASLFIYYTNRLKSITT.DSSLSLMKKSFLIRKIKMDIMpRLKRGELVA......
A8EV86_ALIB4/425-541                 ..DIAELCIIKSILEKPERLDSVLDIVDISMFEYHKTEFELLL...-N.D......IK..D..SS.LNAIVLNEK.LENYD...DERLNQELLVLLHKFYTNKLMAISY.DKELDFKQKANMIRKIKDNIY.QLKQGKLV-s.....
A0A345J733_9PROT/426-542             ..DIAELCIIKTILEKPSTLDKVLDLVDSKVFEYHKNEFELLI...-S.D......IS..N..PS.LNSILLNDK.LEVYD...DERLYREVLLLLSKYFTEKLNTILY.NKTLDFKDKAIKIRVIRDKIS.QLKQGKAV-s.....
E0UP52_SULAO/435-553                 ..DMWELALIKTILEKPEYIEQVLDVIDPSLLQFHSYEFSLVL...QG.K......QD..A..PE.VMAIMVDDT.ITSLK..dEEALNAELITFLTKYYERELKKVNI.ASNISFEEKAFYIRKFRGKIA.KLKRGELVT......
A0A2D3W887_9PROT/428-544             ..DVLELTIIKTLLHKPSLVDTLLDTIDVSMFKTHNMELLALL...KN.E......HE..H..PS.LRKILLDDD.IKIYN...EDELMQAMINFLITYYSSKLLHVKS.-SKLDYEHKSFKIRKIQENIF.KLKQGKLVT......
E6X3A2_NITSE/431-549                 ..DPAWQAILRTLLENERLIDEVLDLIDPRMAGEYQEAFQALI...QG.E......RE..H..PR.LRGIAIAEE.VHPLD...EEAFWRTLRAQMERFYRLKLQEITR.NPRLPYQEKSYWIRKIKTDILpRLKKGELVP......
H5VEY4_HELBI/34-151                  ..DPLEEVLIKYMALDHGLIQNALDFVQVESFRHCQEEFKALC...AG.Q......FD..K..AC.LVAIMLDDR.LPIEP...-HGFKDNLIKLIKRHCEWQITQIHTlYTHLDLSERIAMMNEWKKKRY.LCEQGELV-r.....
A0A3G9GTJ4_9PROT/428-544             ..DIAEKSIIKTLLKTPTLTDMVLDMMDVSMFQRHKDAFEALI...KG.E......-E..N..SE.LLQIDFDDS.IKIYS...EEELKKQLIYFLRRYYEKALDIIKK.YDKLPIEKKMFYLRKYREYIH.KLKRGELVP......
A0A4Q0XZN6_9PROT/425-541             ..DIAELSVIKYILEDKKSLDNILDIVDETMFEFHKNEFIMAV...-K.E......PD..N..TL.LNGILLNEN.ILDYN...YEELHRQLFRFLIKFYSNRLREIQY.NKSYEFREKANLLRKIKDNIY.QLKQGKLV-s.....
A0A1B1U605_9HELI/421-535             .n-LAELVLIKSILESPHYLELALEYLQAECFESHQSAFELIL...QG.E......LE..H..PT.LIGIRINED.IKALT...EKEFQHQVFSFLLNFYEKKLKTIPL.ETGISYNQKLELIAKYRSCIS.QIR------erk...
A0A2A2GTZ4_9HELI/430-553             .y-LAESVLIRTLLENPEWINIAAEYLEPNIFEHHAREYLLLL...QD.QdtnediTK..N..PY.FRPLLIDEN.IKKLQ..tLQEFKEHIKLLVLKAYKKDLALIPR.-LNIHTKHKLESINTLKDKIA.KLTKGELI-s.....
A0A7M3V901_9PROT/433-551             ..DMWELSLIKTIIERPEFIESVLDVIEPSMLQFHSREFSLAL...EN.K......TD..A..PE.LMAILVDEK.IISLH..tAEELNSELITFLTRYYDRELKKINT.ASNISFEQKAFYIRKYRGKIA.QLKRGQLV-r.....
A0A7L8V3F9_9PROT/429-545             ..DIAELSVIKAIAEYPEFVTMILDVCDSNMFSTHKQEFEMVL...-N.N......QD..E..PQ.IRALLLNES.IKSYS...KEELKQQLQFFLIKFHEKNLTLLMN.DSNLDYKEKSTQIRKTRELIS.SLKSGS---ffk...
B6BH19_SULGG/431-549                 ..DMWELSLIKTVLEHPELVDQMLDVLDPSLLQFHSREFALSL...QG.R......LD..E..PS.LMAISIDEQ.IQPLR..dEEALKAELIAFLTKHYERELRKINT.QASLSFEQKAFYIRKFRGKIS.KLKRGELVA......
A0A268U006_9HELI/437-552             .s-IAEKNILLSMKEDVSLFELGLNYLDSKNFSE-PYFFEALL...-E.D......RD..T..KT.LNFLYVEDN.LKTLN...LEDFTAQLRLLLLGCAMSNLEILKN.NIMLDPKERFSQITELQKKIA.KLRSGELV-i.....
E7G310_9HELI/459-579                 .n-PLEEILIKYMALHPELLTQAKNYIHPETFEHCAQEFNTLC...LG.E......-E..N..VQ.ILNIKLDNR.LPTLSenfEQDFKAQLLLFIKRHCQRRIEETNHlNKELNPQERLEILVKWRTKLQ.QINKGELV-q.....
A0A091ANE2_9PROT/427-545             ..DVWELSLTKTLLERPHIIDSLLDFIDPTLLQYHGNEFESAL...RG.N......TD..D..PR.LSALLMDDR.IRSFE..gDEGLKQELITFLITHYNRELKKVTT.QNSVSFDQKSYLIRQYRDKIG.RLKKGELVP......
A0A1B8J998_9HELI/461-567             ..DRLERLILRYMLENENLLERALDFIDSRIFIEYKDAFEALC...AN.K......LD..H..PK.LVGIALDPL.--PLR...QDGFEAELRIFILRFLELELKAQSD.---------IDKIIKIRQKII.KLKKGEL--qp....
T0JQ25_9PROT/431-549                 ..DMWELTLIKTILEHPEFIDQILDVLDASLLQFHSREFVLAL...QG.R......VD..E..PA.LMAIIVDDK.IQALK..dEDALKNELIAFLSKYYERELRTINN.QSSIPFEKKAFNIRKIRDKIA.KLKKGELVA......
#=GC seq_cons                        ..DhhEhslIKolLEcsphl-.sL-hlDsshFppappEFphll...ps.c......h-..c..sp.LhuIhlc-p.lpshs...ccplcppLhhhLh+aYppcLpplpp.ppslshccKhhhI+Kl+ppIt.pLKpG-Ll.......
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