#=GF ID Dynactin_p22
#=GF AC PF07426.15
#=GF DE Dynactin subunit p22
#=GF AU Vella Briffa B;0000-0003-4380-1783
#=GF SE Pfam-B_21336 (release 10.0)
#=GF GA 25.20 25.20;
#=GF TC 25.20 25.20;
#=GF NC 25.00 25.10;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF WK Dynactin
#=GF RN [1]
#=GF RM 9722614
#=GF RT Characterization of the p22 subunit of dynactin reveals the
#=GF RT localization of cytoplasmic dynein and dynactin to the midbody
#=GF RT of dividing cells.
#=GF RA Karki S, LaMonte B, Holzbaur EL;
#=GF RL J Cell Biol 1998;142:1023-1034.
#=GF DR INTERPRO; IPR009991;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This family contains p22, the smallest subunit of dynactin, a
#=GF CC complex that binds to cytoplasmic dynein and is a required
#=GF CC activator for cytoplasmic dynein-mediated vesicular transport.
#=GF CC Dynactin localises to the cleavage furrow and to the midbodies
#=GF CC of dividing cells, suggesting that it may function in
#=GF CC cytokinesis [1]. Family members are approximately 170 residues
#=GF CC long.
#=GF SQ 1805
#=GS A0A2Y9JA85_ENHLU/89-142 AC A0A2Y9JA85.1
#=GS A0A2I4CAN7_9TELE/38-204 AC A0A2I4CAN7.1
#=GS M9LJD0_PSEA3/7-159 AC M9LJD0.1
#=GS A0A3Q1APK6_AMPOC/6-172 AC A0A3Q1APK6.1
#=GS A0A674DT50_SALTR/6-172 AC A0A674DT50.1
#=GS S9X2T7_CAMFR/6-159 AC S9X2T7.1
#=GS A0A7K9QZM4_IRECY/7-171 AC A0A7K9QZM4.1
#=GS K2RQI5_MACPH/12-185 AC K2RQI5.1
#=GS F1A3B2_DICPU/62-217 AC F1A3B2.1
#=GS A0A6P8Y649_THRPL/3-179 AC A0A6P8Y649.1
#=GS A0A850XCB6_PIACA/8-139 AC A0A850XCB6.1
#=GS A0A6J2GRR7_9PASS/7-171 AC A0A6J2GRR7.1
#=GS A0A162NHX0_9PEZI/48-216 AC A0A162NHX0.1
#=GS A0A2K0WTS0_GIBNY/12-181 AC A0A2K0WTS0.1
#=GS A0A8D2DIP2_SCIVU/6-93 AC A0A8D2DIP2.1
#=GS A0A7M7RAG0_STRPU/6-171 AC A0A7M7RAG0.1
#=GS A0A8B6HUV7_MYTGA/5-176 AC A0A8B6HUV7.1
#=GS A0A507FUJ4_9FUNG/9-191 AC A0A507FUJ4.1
#=GS A0A7K9DGZ6_9AVES/1-116 AC A0A7K9DGZ6.1
#=GS B0X536_CULQU/3-175 AC B0X536.1
#=GS A0A421JF75_9ASCO/23-186 AC A0A421JF75.1
#=GS A0A182Y3X7_ANOST/3-174 AC A0A182Y3X7.1
#=GS A0A3M6TXS9_POCDA/9-176 AC A0A3M6TXS9.1
#=GS B3MF26_DROAN/3-167 AC B3MF26.1
#=GS A0A225ULS4_9STRA/1-169 AC A0A225ULS4.1
#=GS A0A2T9ZCG1_9FUNG/25-184 AC A0A2T9ZCG1.1
#=GS A0A2R8ZQ15_PANPA/6-160 AC A0A2R8ZQ15.1
#=GS F6ZVN7_HORSE/6-170 AC F6ZVN7.1
#=GS G9N3N9_HYPVG/12-179 AC G9N3N9.1
#=GS A0A8H7X2N2_9HELO/12-168 AC A0A8H7X2N2.1
#=GS A0A2N3NAP7_9PEZI/12-181 AC A0A2N3NAP7.1
#=GS A0A4Z2EX02_9TELE/102-146 AC A0A4Z2EX02.1
#=GS A0A5N7BI75_9EURO/12-188 AC A0A5N7BI75.1
#=GS A0A7L2QM66_9PASS/7-171 AC A0A7L2QM66.1
#=GS A0A178AW42_9PLEO/11-167 AC A0A178AW42.1
#=GS W7MB54_GIBM7/12-181 AC W7MB54.1
#=GS A0A093H002_DRYPU/1-141 AC A0A093H002.1
#=GS A0A7K9FRM3_STEPR/1-77 AC A0A7K9FRM3.1
#=GS A8N8V6_COPC7/137-303 AC A8N8V6.2
#=GS A0A2J6PJI1_9HELO/12-170 AC A0A2J6PJI1.1
#=GS A0A7N5KHL5_AILME/6-93 AC A0A7N5KHL5.1
#=GS A0A8H4QAS3_9HYPO/12-170 AC A0A8H4QAS3.1
#=GS A0A8C7I855_ONCKI/6-172 AC A0A8C7I855.1
#=GS A0A0F7TUB3_PENBI/12-183 AC A0A0F7TUB3.1
#=GS A0A0V0XNS1_TRIPS/8-145 AC A0A0V0XNS1.1
#=GS A0A7K9KK37_9PASE/7-167 AC A0A7K9KK37.1
#=GS M2QP33_CERS8/26-214 AC M2QP33.1
#=GS A0A6J3CAT8_GALME/3-170 AC A0A6J3CAT8.1
#=GS A0A7L0YCC4_9PASE/7-171 AC A0A7L0YCC4.1
#=GS A0A7K5PG12_9CORV/7-171 AC A0A7K5PG12.1
#=GS A0A8H4CK52_COLGL/12-180 AC A0A8H4CK52.1
#=GS A0A0P7AVJ3_9HYPO/8-172 AC A0A0P7AVJ3.1
#=GS A0A2T2P521_CORCC/12-171 AC A0A2T2P521.1
#=GS A0A1S3G1T7_DIPOR/60-141 AC A0A1S3G1T7.1
#=GS A0A7E5VDM9_TRINI/3-168 AC A0A7E5VDM9.1
#=GS A0A395MTY1_9HYPO/12-176 AC A0A395MTY1.1
#=GS A0A7K6Q2T1_9CORV/7-171 AC A0A7K6Q2T1.1
#=GS A0A1S9DBG5_ASPOZ/774-940 AC A0A1S9DBG5.1
#=GS A0A329RDY3_9STRA/1-166 AC A0A329RDY3.1
#=GS A0A7L3YPC0_FREGA/7-138 AC A0A7L3YPC0.1
#=GS A0A7J8IHY3_ROUAE/6-93 AC A0A7J8IHY3.1
#=GS A0A2A3E869_APICC/3-171 AC A0A2A3E869.1
#=GS A0A6J3RH61_TURTR/6-160 AC A0A6J3RH61.1
#=GS A0A7L1TUB4_PHANI/1-141 AC A0A7L1TUB4.1
#=GS A0A7L2UHF4_BALRX/7-172 AC A0A7L2UHF4.1
#=GS A0A7L0V610_9PASE/1-141 AC A0A7L0V610.1
#=GS A0A8C0YN23_CYPCA/8-159 AC A0A8C0YN23.1
#=GS A0A5C3LCF3_9AGAR/125-292 AC A0A5C3LCF3.1
#=GS A0A2Y9QVH3_TRIMA/6-121 AC A0A2Y9QVH3.1
#=GS A0A0J0XEC5_9TREE/60-236 AC A0A0J0XEC5.1
#=GS A0A3Q0KML8_SCHMA/2-171 AC A0A3Q0KML8.1
#=GS A0A803VKZ7_FICAL/23-171 AC A0A803VKZ7.1
#=GS Q6NTU2_XENLA/3-166 AC Q6NTU2.1
#=GS A0A2V1CMF6_9HELO/12-171 AC A0A2V1CMF6.1
#=GS A0A7N4NGD4_SARHA/6-163 AC A0A7N4NGD4.1
#=GS A0A852EI56_VIDMA/7-171 AC A0A852EI56.1
#=GS A0A8C3HXM0_CHRPI/3-167 AC A0A8C3HXM0.1
#=GS A0A6J3KG97_9HYME/3-172 AC A0A6J3KG97.1
#=GS A0A851WS72_CORMO/7-171 AC A0A851WS72.1
#=GS A0A182GSZ8_AEDAL/20-191 AC A0A182GSZ8.1
#=GS A0A8H8R9H8_9HELO/12-168 AC A0A8H8R9H8.1
#=GS A0A7J8ECT1_MOLMO/89-142 AC A0A7J8ECT1.1
#=GS A0A836F7A5_9HYME/8-177 AC A0A836F7A5.1
#=GS A0A5M3ZC75_ASPTE/339-508 AC A0A5M3ZC75.1
#=GS F9X5N2_ZYMTI/11-182 AC F9X5N2.1
#=GS A0A6P7SZQ2_OCTVU/6-184 AC A0A6P7SZQ2.1
#=GS A0A2S4Q1I5_9PEZI/12-171 AC A0A2S4Q1I5.1
#=GS A0A4Z1P737_9PEZI/14-183 AC A0A4Z1P737.1
#=GS D4A1B8_RAT/2-162 AC D4A1B8.2
#=GS A0A8D0KLY5_SALMN/43-207 AC A0A8D0KLY5.1
#=GS A0A7K5NQD7_CHRMC/7-138 AC A0A7K5NQD7.1
#=GS A0A0B7NH96_9FUNG/4-171 AC A0A0B7NH96.1
#=GS A0A8C5JYU1_JACJA/6-160 AC A0A8C5JYU1.1
#=GS A0A6J3EG07_AYTFU/59-140 AC A0A6J3EG07.1
#=GS A0A2U9CGV4_SCOMX/6-172 AC A0A2U9CGV4.1
#=GS A0A1V6YYZ3_PENNA/12-185 AC A0A1V6YYZ3.1
#=GS A0A8B8XY74_BALMU/6-165 AC A0A8B8XY74.1
#=GS A0A3Q0EE40_CARSF/6-141 AC A0A3Q0EE40.1
#=GS A0A2U3ZEH2_ODORO/89-142 AC A0A2U3ZEH2.1
#=GS T1GL68_MEGSC/26-147 AC T1GL68.1
#=GS A0A2K5Q174_CEBIM/89-142 AC A0A2K5Q174.1
#=GS A0A2Y9QMT8_TRIMA/6-121 AC A0A2Y9QMT8.1
#=GS E9DC18_COCPS/16-181 AC E9DC18.1
#=GS A0A6P6I8W1_PUMCO/6-65 AC A0A6P6I8W1.1
#=GS A0A6J0B9L3_NEOLC/3-172 AC A0A6J0B9L3.1
#=GS A0A7K8X617_9PICI/6-170 AC A0A7K8X617.1
#=GS A0A6P6BY61_PTEVA/6-175 AC A0A6P6BY61.1
#=GS A0A0G2HZ55_9PEZI/13-173 AC A0A0G2HZ55.1
#=GS A0A7L2BUA4_9PASS/7-136 AC A0A7L2BUA4.1
#=GS A0A2T7PWL9_POMCA/6-157 AC A0A2T7PWL9.1
#=GS A0A7L4NKN9_9AVES/7-172 AC A0A7L4NKN9.1
#=GS A0A1R0GMA4_9FUNG/1-170 AC A0A1R0GMA4.1
#=GS A0A5C3P7V0_9APHY/61-248 AC A0A5C3P7V0.1
#=GS A0A7K6A4F6_ONYCO/7-171 AC A0A7K6A4F6.1
#=GS W2QI43_PHYPN/1-169 AC W2QI43.1
#=GS A0A444U675_ACIRT/42-159 AC A0A444U675.1
#=GS A0A7K9WY52_9GRUI/1-141 AC A0A7K9WY52.1
#=GS A0A3Q0CCP8_MESAU/4-88 AC A0A3Q0CCP8.1
#=GS A0A8R1WHS1_BOMMO/3-169 AC A0A8R1WHS1.1
#=GS A0A8B7JDT9_9AVES/7-148 AC A0A8B7JDT9.1
#=GS A0A8H8JEU6_9AGAM/111-289 AC A0A8H8JEU6.1
#=GS A0A8B9SCE9_APTOW/40-196 AC A0A8B9SCE9.1
#=GS A0A093BX28_9AVES/1-115 AC A0A093BX28.1
#=GS L8I4S0_9CETA/6-170 AC L8I4S0.1
#=GS A0A2I0TIG0_LIMLA/81-131 AC A0A2I0TIG0.1
#=GS A0A6P8H0B2_ACTTE/93-147 AC A0A6P8H0B2.1
#=GS A0A3P7G1E8_HYDTA/83-250 AC A0A3P7G1E8.1
#=GS A0A8H6VE22_9PEZI/11-184 AC A0A8H6VE22.1
#=GS A0A179FQ42_METCM/18-186 AC A0A179FQ42.1
#=GS A0A164PXH1_9CRUS/4-170 AC A0A164PXH1.1
#=GS A0A8J5D3M6_CHIOP/6-165 AC A0A8J5D3M6.1
#=GS F2SZ82_TRIRC/13-178 AC F2SZ82.1
#=GS A0A8H2VSC2_9HELO/12-172 AC A0A8H2VSC2.1
#=GS A0A1V6SZM4_9EURO/12-185 AC A0A1V6SZM4.1
#=GS A0A4V1IVY8_9FUNG/72-246 AC A0A4V1IVY8.1
#=GS R1ES09_BOTPV/12-185 AC R1ES09.1
#=GS A0A2K6GTQ6_PROCO/6-160 AC A0A2K6GTQ6.1
#=GS A0A6A5EGS4_PERFL/6-172 AC A0A6A5EGS4.1
#=GS A0A7L3L008_9CHAR/7-172 AC A0A7L3L008.1
#=GS E3QNZ2_COLGM/12-181 AC E3QNZ2.1
#=GS A0A7K8LHA0_9GRUI/9-158 AC A0A7K8LHA0.1
#=GS A0A0M9A422_9HYME/3-172 AC A0A0M9A422.1
#=GS A0A670ZRW7_PSETE/17-163 AC A0A670ZRW7.1
#=GS A0A0B7F943_THACB/103-281 AC A0A0B7F943.1
#=GS A0A6P8AXU6_MAGGR/17-181 AC A0A6P8AXU6.1
#=GS A0A8B9ETC7_ANSCY/32-194 AC A0A8B9ETC7.1
#=GS A0A7L2TLV3_POMRU/2-166 AC A0A7L2TLV3.1
#=GS A0A0D7AWJ9_9AGAR/83-262 AC A0A0D7AWJ9.1
#=GS A0A2N5T030_9BASI/33-220 AC A0A2N5T030.1
#=GS A0A8J4N187_EUDMI/9-173 AC A0A8J4N187.1
#=GS A0A8C3L8G9_CHRPC/1-124 AC A0A8C3L8G9.1
#=GS A0A814GNU0_9BILA/8-170 AC A0A814GNU0.1
#=GS A0A8H7PWM2_MORIS/5-131 AC A0A8H7PWM2.1
#=GS A0A7L3SRH9_RISTR/1-77 AC A0A7L3SRH9.1
#=GS A0A4Z1JMK2_9HELO/12-172 AC A0A4Z1JMK2.1
#=GS A0A7L4FCH7_9COLU/7-136 AC A0A7L4FCH7.1
#=GS A0A0D9RCN6_CHLSB/6-170 AC A0A0D9RCN6.1
#=GS A0A0L1JCA0_ASPNO/624-790 AC A0A0L1JCA0.1
#=GS L5KE50_PTEAL/6-170 AC L5KE50.1
#=GS A0A7M3RL86_SPIER/2-169 AC A0A7M3RL86.1
#=GS A0A2I3MBN2_PAPAN/6-160 AC A0A2I3MBN2.1
#=GS A0A5N6EZ14_9EURO/12-178 AC A0A5N6EZ14.1
#=GS A0A8C2UQZ0_CHILA/6-144 AC A0A8C2UQZ0.1
#=GS A0A6P3RG31_PTEVA/6-170 AC A0A6P3RG31.1
#=GS A0A067TC02_GALM3/34-228 AC A0A067TC02.1
#=GS A0A1V6RHP3_9EURO/12-185 AC A0A1V6RHP3.1
#=GS A0A8B6HUM4_MYTGA/5-151 AC A0A8B6HUM4.1
#=GS B8PD14_POSPM/39-222 AC B8PD14.1
#=GS A0A0L0G8Q2_9EUKA/14-176 AC A0A0L0G8Q2.1
#=GS A0A0F0I858_ASPPU/12-178 AC A0A0F0I858.1
#=GS T1I6F7_RHOPR/12-176 AC T1I6F7.1
#=GS A0A8B8GRV0_9HEMI/5-171 AC A0A8B8GRV0.1
#=GS A0A2G5V958_9PELO/7-172 AC A0A2G5V958.1
#=GS A0A7J7W2D0_PIPKU/6-93 AC A0A7J7W2D0.1
#=GS H2QX67_PANTR/6-92 AC H2QX67.2
#=GS A0A182GGZ6_AEDAL/3-174 AC A0A182GGZ6.1
#=GS A0A4Q4W4Z6_9PEZI/12-173 AC A0A4Q4W4Z6.1
#=GS A0A5G2Q8X4_PIG/6-160 AC A0A5G2Q8X4.1
#=GS A0A7K9M4X5_OCETE/7-171 AC A0A7K9M4X5.1
#=GS A0A8J2N7M1_9PLEO/11-174 AC A0A8J2N7M1.1
#=GS A0A286UUV4_9AGAM/126-289 AC A0A286UUV4.1
#=GS A0A2U9CGL1_SCOMX/6-126 AC A0A2U9CGL1.1
#=GS A0A6J1XRH4_ACIJB/6-160 AC A0A6J1XRH4.1
#=GS A0A2K5MXG5_CERAT/6-160 AC A0A2K5MXG5.1
#=GS F9F2W7_FUSOF/12-181 AC F9F2W7.1
#=GS A0A7L0QQ20_SETKR/7-162 AC A0A7L0QQ20.1
#=GS A0A7J8ECM1_MOLMO/6-144 AC A0A7J8ECM1.1
#=GS A0A286XNI0_CAVPO/6-170 AC A0A286XNI0.1
#=GS A0A814AXR9_9BILA/10-173 AC A0A814AXR9.1
#=GS A0A5G2RCY9_PIG/6-91 AC A0A5G2RCY9.2
#=GS A0A7K8ZUS2_9PASS/7-171 AC A0A7K8ZUS2.1
#=GS A0A8C7CD68_NEOVI/6-140 AC A0A8C7CD68.1
#=GS A0A2I3N3K3_PAPAN/6-93 AC A0A2I3N3K3.1
#=GS A0A7L1TMU9_ARAGA/8-114 AC A0A7L1TMU9.1
#=GS A0A8J5B9G9_9DIPT/3-165 AC A0A8J5B9G9.1
#=GS H2RKX5_TAKRU/6-172 AC H2RKX5.2
#=GS A0A5F5Y2G4_FELCA/6-132 AC A0A5F5Y2G4.1
#=GS A0A0K6G1B0_9AGAM/103-281 AC A0A0K6G1B0.1
#=GS A0A7L1W5E9_9PASS/7-171 AC A0A7L1W5E9.1
#=GS A0A5F9CYT8_RABIT/6-124 AC A0A5F9CYT8.1
#=GS A0A813I9W7_POLGL/24-195 AC A0A813I9W7.1
#=GS A0A6J3RGI4_TURTR/88-142 AC A0A6J3RGI4.1
#=GS A0A2K5F396_AOTNA/6-93 AC A0A2K5F396.1
#=GS A0A669CKS7_ORENI/6-172 AC A0A669CKS7.1
#=GS A0A8C6DAE4_MOSMO/6-93 AC A0A8C6DAE4.1
#=GS A0A2K6LDB6_RHIBE/6-93 AC A0A2K6LDB6.1
#=GS A0A090CRG7_PODAN/12-174 AC A0A090CRG7.1
#=GS A0A8C0YDN8_CYPCA/13-160 AC A0A8C0YDN8.1
#=GS A0A8C7CFB3_NEOVI/6-93 AC A0A8C7CFB3.1
#=GS A0A6P8WX36_GYMAC/6-172 AC A0A6P8WX36.1
#=GS A0A8B7PWC4_HIPAR/6-170 AC A0A8B7PWC4.1
#=GS A0A7K4PWM3_MELMO/6-170 AC A0A7K4PWM3.1
#=GS V4A9H3_LOTGI/6-178 AC V4A9H3.1
#=GS A0A7J8IH31_ROUAE/6-170 AC A0A7J8IH31.1
#=GS A0A5N6SGC7_ASPPS/12-178 AC A0A5N6SGC7.1
#=GS S7ZW51_PENO1/12-183 AC S7ZW51.1
#=GS A0A1Q3EBD9_LENED/59-259 AC A0A1Q3EBD9.1
#=GS A0A125PIN2_9BASI/13-192 AC A0A125PIN2.1
#=GS H2YTE0_CIOSA/6-167 AC H2YTE0.1
#=GS A0A8I5YB95_RAT/6-144 AC A0A8I5YB95.1
#=GS A0A819P369_9BILA/10-173 AC A0A819P369.1
#=GS A0A0D2WXN5_CAPO3/9-197 AC A0A0D2WXN5.1
#=GS A0A8C4L3N1_EQUAS/6-170 AC A0A8C4L3N1.1
#=GS A0A833SD29_9HYME/3-172 AC A0A833SD29.1
#=GS A0A7K4WJ25_9TYRA/7-171 AC A0A7K4WJ25.1
#=GS A0A0J8QQX1_COCIT/16-181 AC A0A0J8QQX1.1
#=GS A0A7J8ED17_MOLMO/6-170 AC A0A7J8ED17.1
#=GS A0A4P9Y583_9FUNG/100-252 AC A0A4P9Y583.1
#=GS X6RA56_HUMAN/6-138 AC X6RA56.1
#=GS A0A8C9D869_PANLE/6-152 AC A0A8C9D869.1
#=GS A0A7L2Z6U1_JACJC/1-141 AC A0A7L2Z6U1.1
#=GS A0A397IE97_9GLOM/67-247 AC A0A397IE97.1
#=GS A0A7K5X5N3_9CHAR/7-171 AC A0A7K5X5N3.1
#=GS A0A091FCA8_CORBR/1-139 AC A0A091FCA8.1
#=GS A0A8C6YWH5_NOTPE/33-163 AC A0A8C6YWH5.1
#=GS H2QX67_PANTR/88-142 AC H2QX67.2
#=GS A0A2Y9QMT8_TRIMA/122-184 AC A0A2Y9QMT8.1
#=GS A0A6J3RGT9_TURTR/6-165 AC A0A6J3RGT9.1
#=GS A0A2U9CJ61_SCOMX/6-172 AC A0A2U9CJ61.1
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