GenomeNet

Database: Pfam
Entry: Endotoxin_C2
LinkDB: Endotoxin_C2
Original site: Endotoxin_C2 
#=GF ID   Endotoxin_C2
#=GF AC   PF18449.4
#=GF DE   Delta endotoxin 
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   ECOD:EUF02217
#=GF GA   30.70 30.70;
#=GF TC   30.70 30.70;
#=GF NC   30.40 30.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Cry1Ac
#=GF RN   [1]
#=GF RM   25139047
#=GF RT   Structure of the full-length insecticidal protein Cry1Ac reveals
#=GF RT   intriguing details of toxin packaging into in vivo formed
#=GF RT   crystals.
#=GF RA   Evdokimov AG, Moshiri F, Sturman EJ, Rydel TJ, Zheng M, Seale
#=GF RA   JW, Franklin S;
#=GF RL   Protein Sci. 2014;23:1491-1497.
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This is domain (D-VI) can be found in Bacillus thuringiensis
#=GF CC   (Bt) insecticidal protein Cry1Ac. Full length structural
#=GF CC   analysis reveal that Cry1Ac contains seven distinct domains
#=GF CC   (DI-DVII): the three canonical toxin core domains (D-I through
#=GF CC   D-III) and four protoxin domains (D-IV through D-VII). Cry1Ac is
#=GF CC   sickle-shaped with the toxic core as handle and the protoxin
#=GF CC   domains as the blade. Domains IV and VI are alpha-bundles that
#=GF CC   resemble structural/interaction domains such as spectrin [PDB
#=GF CC   ID: 1CUN] or bacterial fibrinogen-binding complement inhibitor
#=GF CC   [1].
#=GF SQ   120
#=GS A0A099WKL4_9LIST/689-753    AC A0A099WKL4.1
#=GS A0A099WGA3_9LIST/837-900    AC A0A099WGA3.1
#=GS A0A099WD64_9LIST/476-539    AC A0A099WD64.1
#=GS A0A099WGN8_9LIST/631-695    AC A0A099WGN8.1
#=GS A0A150LGJ8_9BACI/198-260    AC A0A150LGJ8.1
#=GS A0A099WCZ9_9LIST/1766-1830  AC A0A099WCZ9.1
#=GS A0A099W9V9_9LIST/660-724    AC A0A099W9V9.1
#=GS A0A1L8WHP4_9ENTE/40-102     AC A0A1L8WHP4.1
#=GS A0A291BZB5_BROTH/657-717    AC A0A291BZB5.1
#=GS M8DZ21_9BACL/1192-1255      AC M8DZ21.1
#=GS A0A099VYR1_9LIST/282-345    AC A0A099VYR1.1
#=GS A0A099WEU3_9LIST/403-466    AC A0A099WEU3.1
#=GS A0A1X7LPV4_9BACL/516-578    AC A0A1X7LPV4.1
#=GS A0A099WBG6_9LIST/204-266    AC A0A099WBG6.1
#=GS A0A099WGA3_9LIST/767-830    AC A0A099WGA3.1
#=GS C0ZKG4_BREBN/527-586        AC C0ZKG4.1
#=GS A0A1Q2D3A7_9ENTE/235-297    AC A0A1Q2D3A7.1
#=GS A0A1V4HG96_9BACL/161-223    AC A0A1V4HG96.1
#=GS A0A291BZB5_BROTH/593-653    AC A0A291BZB5.1
#=GS A0A6I1FKT7_9BACI/847-916    AC A0A6I1FKT7.1
#=GS A0A099W9V9_9LIST/440-503    AC A0A099W9V9.1
#=GS A0A090YDK5_PAEMA/161-223    AC A0A090YDK5.1
#=GS A0A099WD64_9LIST/314-375    AC A0A099WD64.1
#=GS A0A099WLS7_9LIST/366-427    AC A0A099WLS7.1
#=GS A0A3D8TS14_9LIST/258-322    AC A0A3D8TS14.1
#=GS A0A099W9V9_9LIST/512-576    AC A0A099W9V9.1
#=GS A0A6M1UA04_9BACL/1107-1169  AC A0A6M1UA04.1
#=GS M8DZ21_9BACL/1123-1186      AC M8DZ21.1
#=GS A0A099VYR1_9LIST/497-560    AC A0A099VYR1.1
#=GS A0A099WI22_9LIST/40-105     AC A0A099WI22.1
#=GS A0A291BZB5_BROTH/718-780    AC A0A291BZB5.1
#=GS A0A291BZB5_BROTH/527-589    AC A0A291BZB5.1
#=GS A0A1L8WHN3_9ENTE/271-333    AC A0A1L8WHN3.1
#=GS A0A099WGN8_9LIST/705-769    AC A0A099WGN8.1
#=GS W7CZ22_9LIST/149-211        AC W7CZ22.1
#=GS A0A4Q2LQM1_9BACL/522-584    AC A0A4Q2LQM1.1
#=GS N9WQP2_CLOIN/38-99          AC N9WQP2.1
#=GS A0A099WLS7_9LIST/502-565    AC A0A099WLS7.1
#=GS A0A291BZB5_BROTH/464-526    AC A0A291BZB5.1
#=GS A0A0R1VYV2_9LACO/41-102     AC A0A0R1VYV2.1
#=GS A0A3D8TSS9_9LIST/291-348    AC A0A3D8TSS9.1
#=GS W7CZ22_9LIST/280-343        AC W7CZ22.1
#=GS A0A099WEU3_9LIST/472-535    AC A0A099WEU3.1
#=GS A0A430A2A4_9ENTE/186-248    AC A0A430A2A4.1
#=GS W7CZ22_9LIST/614-676        AC W7CZ22.1
#=GS A0A099WLS7_9LIST/433-496    AC A0A099WLS7.1
#=GS A0A6M1UA04_9BACL/975-1039   AC A0A6M1UA04.1
#=GS A0A3D8TQB9_9LIST/251-309    AC A0A3D8TQB9.1
#=GS A0A099W4G4_9LIST/298-361    AC A0A099W4G4.1
#=GS A0A398BK47_9BACI/167-229    AC A0A398BK47.1
#=GS A0A1L8W7E4_9ENTE/87-146     AC A0A1L8W7E4.1
#=GS A0A099VYR1_9LIST/796-860    AC A0A099VYR1.1
#=GS Q7AP83_LISMO/201-264        AC Q7AP83.1
#=GS A0A6G7XXI4_9FIRM/1276-1336  AC A0A6G7XXI4.1
#=GS A0A099WGN8_9LIST/557-621    AC A0A099WGN8.1
#=GS A0A099WKL4_9LIST/620-685    AC A0A099WKL4.1
#=GS A0A099WBG6_9LIST/141-201    AC A0A099WBG6.1
#=GS A0A099VYR1_9LIST/355-418    AC A0A099VYR1.1
#=GS C0ZKG4_BREBN/394-457        AC C0ZKG4.1
#=GS A0A1L8WHM8_9ENTE/42-106     AC A0A1L8WHM8.1
#=GS A0A5R9E0Y8_9LACT/47-108     AC A0A5R9E0Y8.1
#=GS A0A099VYR1_9LIST/648-712    AC A0A099VYR1.1
#=GS A0A099WKL4_9LIST/491-552    AC A0A099WKL4.1
#=GS A0A6G7XXI4_9FIRM/486-546    AC A0A6G7XXI4.1
#=GS A0A1L8W7E4_9ENTE/279-338    AC A0A1L8W7E4.1
#=GS A0A099W4G4_9LIST/232-295    AC A0A099W4G4.1
#=GS A0A291BZB5_BROTH/400-462    AC A0A291BZB5.1
#=GS C0ZKG4_BREBN/460-521        AC C0ZKG4.1
#=GS Q38Z85_LACSS/161-223        AC Q38Z85.1
#=GS A0A099WGA3_9LIST/557-620    AC A0A099WGA3.1
#=GS A0A099VYR1_9LIST/211-272    AC A0A099VYR1.1
#=GS A0A1E5H317_9ENTE/216-278    AC A0A1E5H317.1
#=GS A0A099WKL4_9LIST/550-611    AC A0A099WKL4.1
#=GS A0A099VYR1_9LIST/427-491    AC A0A099VYR1.1
#=GS A0A099WGN8_9LIST/410-472    AC A0A099WGN8.1
#=GS A0A099WGA3_9LIST/417-480    AC A0A099WGA3.1
#=GS A0A099WGN8_9LIST/482-546    AC A0A099WGN8.1
#=GS A0A1L8WCY4_9ENTE/563-625    AC A0A1L8WCY4.1
#=GS A0A371IS10_9FIRM/593-655    AC A0A371IS10.1
#=GS A0A2X3IL40_9LIST/112-175    AC A0A2X3IL40.1
#=GS A0A099WEU3_9LIST/334-397    AC A0A099WEU3.1
#=GS A0A2U3AJ91_9BACL/65-127     AC A0A2U3AJ91.1
#=GS A0A1X7LPV4_9BACL/584-646    AC A0A1X7LPV4.1
#=GS A0A099W4G4_9LIST/510-573    AC A0A099W4G4.1
#=GS A0A0R2J1D4_9LACO/44-106     AC A0A0R2J1D4.1
#=GS A0A3D8TTR9_9LIST/225-287    AC A0A3D8TTR9.1
#=GS A0A099WGA3_9LIST/627-690    AC A0A099WGA3.1
#=GS A0A099WD64_9LIST/225-289    AC A0A099WD64.1
#=GS Q7AP83_LISMO/141-198        AC Q7AP83.1
#=GS A0A099WBG6_9LIST/269-328    AC A0A099WBG6.1
#=GS A0A6M1UA04_9BACL/844-908    AC A0A6M1UA04.1
#=GS W7CZ22_9LIST/546-608        AC W7CZ22.1
#=GS A0A1D2LBQ7_BROTH/727-789    AC A0A1D2LBQ7.1
#=GS V7HSW9_9LACO/267-331        AC V7HSW9.1
#=GS A0A099W4G4_9LIST/440-503    AC A0A099W4G4.1
#=GS A0A1E5GZU7_9ENTE/207-267    AC A0A1E5GZU7.1
#=GS W7CZ22_9LIST/477-540        AC W7CZ22.1
#=GS A0A099W9V9_9LIST/586-650    AC A0A099W9V9.1
#=GS A0A099WI22_9LIST/204-267    AC A0A099WI22.1
#=GS A0A291BZB5_BROTH/272-334    AC A0A291BZB5.1
#=GS A0A6M1UA04_9BACL/1041-1105  AC A0A6M1UA04.1
#=GS A0A1D2LBQ7_BROTH/525-587    AC A0A1D2LBQ7.1
#=GS K8E1J7_CARML/209-271        AC K8E1J7.2
#=GS A0A099W9V9_9LIST/733-797    AC A0A099W9V9.1
#=GS A0A3M8DYS1_9BACL/840-902    AC A0A3M8DYS1.1
#=GS A0A099WEU3_9LIST/265-328    AC A0A099WEU3.1
#=GS A0A099VYR1_9LIST/572-636    AC A0A099VYR1.1
#=GS W7CZ22_9LIST/682-744        AC W7CZ22.1
#=GS A0A6M1UA04_9BACL/910-974    AC A0A6M1UA04.1
#=GS A0A099WGA3_9LIST/487-550    AC A0A099WGA3.1
#=GS A0A3S0BMP8_9BACL/161-223    AC A0A3S0BMP8.1
#=GS A0A099WGA3_9LIST/697-760    AC A0A099WGA3.1
#=GS A0A099VYR1_9LIST/722-786    AC A0A099VYR1.1
#=GS Q38XP9_LACSS/83-143         AC Q38XP9.1
#=GS A0A291BZB5_BROTH/336-398    AC A0A291BZB5.1
#=GS N0AVQ0_9BACI/172-234        AC N0AVQ0.1
#=GS F9UPV7_LACPL/48-110         AC F9UPV7.1
#=GS A0A1D2LBQ7_BROTH/659-721    AC A0A1D2LBQ7.1
#=GS A0A6G7XCX1_9MICO/275-333    AC A0A6G7XCX1.1
#=GS W7CZ22_9LIST/349-411        AC W7CZ22.1
A0A099WKL4_9LIST/689-753               .......att---AAAKKAVDELFI.NN......TPSSnvIKPTTDQAKINAAQALIN..KVTD..PTKKVELQKDLDKAQNLLDA......
A0A099WGA3_9LIST/837-900               ........aa--QAKAREAVNNLFA.SQ......NPNG.dLKTGLTQAEIDAAQALID..QVTD..PAKKAELQADLNKAQQQLNA......
A0A099WD64_9LIST/476-539               ........ak---QMATNAVLDLFK.DN......EPNTntLKPTTTQKTIDYVQSLIN..VVQD..ATVKANMQKELDKAESILNA......
A0A099WGN8_9LIST/631-695               .........a-KQDAALKAVNELFN.NN......TPATdaIKGTTDQAAINAAKALVD..AVID..PTVKAALQKDLNRAQELLDA......
A0A150LGJ8_9BACI/198-260               .........m-KIKKAKDKINQLFL.DS......DHNQ..IKSKVNREDYNESKKLVQ..EIKS..ERIRKNLSKLLYKIDQQL--ka....
A0A099WCZ9_9LIST/1766-1830             .......qte---DTATKAVSELFT.DN......NPDSdsLKAATDQKALDAAQKAVD..AVQD..TTAKAALQTQLNKAKELF--an....
A0A099W9V9_9LIST/660-724               ........ar--QEAALKAVNELFN.SD......NPSTdaIKGSTTQDSIDAAQKLVD..AVTD..PTVKAELQKDLDRAQELLDA......
A0A1L8WHP4_9ENTE/40-102                .........t-ALTEATTTVNNLFY.GN......DENH..AKPSNTNAQIDAARNQVT..ALPD..SAQKSVLLKKVKKAQQAYDE......
A0A291BZB5_BROTH/657-717               .....agkva-------EDVNNLFA.DK......EHTT..LADGITQKDIDVAKDQVN..KLTD..GAKKEELLNEIQKAQDLL--ta....
M8DZ21_9BACL/1192-1255                 .........e-KLEAAKKAVEELFE.DY......STKA.aLAAGVDQAAIDAAKAKVE..ALDN.sVAEKVDLLADVEAAQDLL--t.....
A0A099VYR1_9LIST/282-345               ........ar--QEAADASVKNLFN.NN......DVNG.tIKDATNQTAIDDAKKLVD..AVTD..ATKKAELEKNLKEAQEQLDA......
A0A099WEU3_9LIST/403-466               ........qr--EAEAKAATNGLFV.DN......DATK.gIKPSTDQAAIDVAQAKID..LVTD..ATVKAELQAALDKAQAELDA......
A0A1X7LPV4_9BACL/516-578               ..........SNLIAAKNAVAWLFL.DS......TKTA..LKAGVDQAAIDAAKAKVE..LVAD..GADKSALVADLQLAQQLL--ta....
A0A099WBG6_9LIST/204-266               .........h--EQEATATTHALFT.DA......NPTN.dITEDLTQEAIDAASNQVS..ALKE..SPTKNTLQANIDKAQQQL--te....
A0A099WGA3_9LIST/767-830               .........a-AQNKAQEAVNNLFA.SQ......NPAN.dAKAGLTQAEIDAAQALIN..QVTD..PAKKAELQASLDKAQQQLDA......
C0ZKG4_BREBN/527-586                   .......eev------KRAVEGLFT.TN......DMIE..LRPKVTQEMIDAAYSKVE..LLRE..GPEKTHWMSYVEKAQMLFN-n.....
A0A1Q2D3A7_9ENTE/235-297               ........ql--IATAETAVKSLFL.NS......EHVF..LKENMTKNDLTKAQTDLN..KIKN..QSNYNDLNRLFETAEATFNR......
A0A1V4HG96_9BACL/161-223               ..........EQILTATRMVDALFT.SS......EKST..VKESITRTEIDNAKAKIN..DIKQ..DKAKESLLSFIQLTDSYID-s.....
A0A291BZB5_BROTH/593-653               .....agkva-------EDVNNLFA.DK......EHTT..LADGITQKDIDVAKEAVN..KLTD..EAKKEELLNEIQKAQDLL--ta....
A0A6I1FKT7_9BACI/847-916               ........da--YKKAREAVDGLYK.EDwydyeeSEER..LKEGLTQEEIDAARALVQ..SLSS.eFTEKEHLEYRVDYADYLFN-k.....
A0A099W9V9_9LIST/440-503               ........ta---EIAQKAVNELFT.NN......DTATdtIKDTTTQASIDAAQALVN..KVTD..PATKAALQKDLDRAQELLNE......
A0A090YDK5_PAEMA/161-223               ..........KQISAATKKVDSLFT.SS......EKTA..VKKSIKQTEINEAKASVK..KIKQ..HKAKTDLLSYVQVADVYLDA......
A0A099WD64_9LIST/314-375               ........nf----VASNAVLGLFE.NN......NPSTntLKSTTDQQAIDAVQKLVD..GVVD..ATVRANMQVDIERAKDLL--k.....
A0A099WLS7_9LIST/366-427               ........fd----EASKAVNNLFI.NK......DPNG.kITDILKQADIDAAQALVN..KVVD..PTEKATLQANLNKAQKQLDD......
A0A3D8TS14_9LIST/258-322               ........qg--IEEVRTGVDGLFT.DD......THSK..LRLPIVQEDLDAVQDQIDldLILD..PLVKDFYQKELDKAQALLDA......
A0A099W9V9_9LIST/512-576               ........dr--QAAALKAVNELFN.ND......QPSTdaIKDSTNQEAIDAAQKLVD..AVTD..PVVKAALQKDLDRAQELLDA......
A0A6M1UA04_9BACL/1107-1169             .........v-ALEAARQAVAALFT.DE......TKTA..LAQGVTETEIAAAEAKVN..ALPD..GQDKDALVQDIATARELL--aa....
M8DZ21_9BACL/1123-1186                 .........e-ALKEATSAVSGLFK.DD......SKSS..LATGVDQAAIDAAKAKVE..ALAD.sVAEKTDLLKDVKKAQDLLDA......
A0A099VYR1_9LIST/497-560               ........ar--QEAAEAGLKDLFNgND......VNGK..IKDTTNQEAIDKVQDLIN..KVTD..PTIKADLQKDLDRAQELLDA......
A0A099WI22_9LIST/40-105                ........se---KTATDAISALFA.NN......NPSTnvLKTTTNQQTIDAAQQLLD..AVTGmsDTTKANAQAAITQARALLD-l.....
A0A291BZB5_BROTH/718-780               ....keeqkv------AEDVNNLFA.DD......EHTI..LADGITQKDIDVAKDQVN..KLID..EAKKEELLNEIQKAQDLLNE......
A0A291BZB5_BROTH/527-589               .........k-EEQKAVENVNNLFA.DG......EHTT..LADGITQKDIDVAKEAVN..KLTD..EAKKEELLNEIQKAQDLL--ta....
A0A1L8WHN3_9ENTE/271-333               ........dt---QKAIKATNALFT.DT......TYTK..LAATTTSKSIHKAFKLTQ..KVPS.eDHNHALLLDILTKAQTLL--ln....
A0A099WGN8_9LIST/705-769               .........a-KQDAALKAVNELFN.NN......TPATdaIKGTTDQAAINAAKALVD..AVTD..PTVKAALQKDLNRAQELLDA......
W7CZ22_9LIST/149-211                   .......aas---KKAETAVKALYT.NS......SMTS..IHGNLTQALLDQATTLAN..AVPV..DSKKQTFLANIAKAQNQYN-v.....
A0A4Q2LQM1_9BACL/522-584               ..........SKLIAAKNAVASLFT.DS......TKTA..LKAGVDQAAIDAAKAKVD..LVDE..GAEKSALKKAIEIAQDLL--sq....
N9WQP2_CLOIN/38-99                     ........qs--TSVARKEVLSLFK.DQ......TCTR..LADGITQENIDQARAKVE..T-VN..QAEKEGLTALITKANAML--qq....
A0A099WLS7_9LIST/502-565               ........ea--EDKAREAVNSLFT.NK......NPNG.sIKSPLTQAEIDAAQVLIN..KVTD..PTKKAALQADLDKAQNQWNA......
A0A291BZB5_BROTH/464-526               ......detn----KAEENVNNLFA.DD......EHTT..LAEGVTQQDIDAAKEAAN..KVTD..KAKKEELLNEIQKAQDLL--ta....
A0A0R1VYV2_9LACO/41-102                ..........SKLTAARTDVNSLF-.DV......QYTE..LRDGVEEDEIEAVNKEVN..SLPS..SNNRTKLKKHMKAAYHLFPA......
A0A3D8TSS9_9LIST/291-348               .....tndis----------DDLFT.DS......SYSE..LKLHVVEEDITAADKWLK..LILD..PEAKDSLTNRMNWAKELL--aa....
W7CZ22_9LIST/280-343                   ..........NNLLAATDKVNELFS.DD......EHST..IGQDVDQATIDTVKQLVA.dTIVP..GSNKDKLEAEIAKAQQLLDD......
A0A099WEU3_9LIST/472-535               ........qr--EAEAKAAINDLFI.GN......NPAN.nIKDTTTQAAIDAAQVKVN..AVTD..PAVKAELQAQVDKAQAQIN-t.....
A0A430A2A4_9ENTE/186-248               ......qmva----SANTDVKSLFL.NS......EHTF..LKKGITKSDFNKAKDALD..KIKT..QSEFNDMNKLYEQAESIFN-n.....
W7CZ22_9LIST/614-676                   .........t-DMKAAQEATNNLFA.DE......AKSS..LADDISQAMIDSAKELVN..KLPN..GKEKESLLADVTQAQALLDE......
A0A099WLS7_9LIST/433-496               ........ea--ENKAREAVNNLFT.SK......DPNG.nITSTMTQADVDAAQALIN..KVND..PTKKAELQADLDKAQKQLDD......
A0A6M1UA04_9BACL/975-1039              ..........QALQAAKQAVEALFV.DY......STKA.aLAANVDQTAINAAKAKVD..ALND.sVTEKASLLADIQTAQDLLDA......
A0A3D8TQB9_9LIST/251-309               ......elgi----------SQLFT.DD......THTK..LRPSVNQQDIDAVQDQIDldLIVN..LDVSAEYQKELNKAQSLLD-l.....
A0A099W4G4_9LIST/298-361               ........da--ENKAQDVVNNLFE.NK......NPNG.dITGNVTKDDIDAAQDLID..KLAN..TTKKAELQTALNKAKQQL--td....
A0A398BK47_9BACI/167-229               ..........KKIEEATNKVNQLFA.GA......DYKE..VKSEVNRGEFNKVKNLVN..EIRQ..EKAKRNLSTLINKVDQYL--te....
A0A1L8W7E4_9ENTE/87-146                .........d-ALQQATRTVNNLF-.--......DRFG..AKQSNTKAQIDAARKQVT..ALSN..SMQKTELLNKVEQAQQAYDE......
A0A099VYR1_9LIST/796-860               ........ar--EEAAKNAVDELFQ.GN......NPSTgiIKETTDQSVIDAAQDLIN..KVTD..PTIKKDLQKELDKAQDLLD-i.....
Q7AP83_LISMO/201-264                   .........a-QEQAAIQAVNQLFL.ED......SPVN.sIKAETTQDLIDQAQTLVD..VLPA..SELKDTLQANIVKAQTELDE......
A0A6G7XXI4_9FIRM/1276-1336             .........s-AMVTARDRANGLF-.-T......AQNT..LRSDVTQSHIDAVKELIG..LIPN..GTLRNTLNTEIDRAQTQLN-q.....
A0A099WGN8_9LIST/557-621               .........a-KQDAALKAVNELFN.NN......TPSTdaIKGTTDQAAINAAKALVD..AVTD..PTVKAALQKDLNRAQELLDA......
A0A099WKL4_9LIST/620-685               ......qiqk---AIAEYVVNQLFV.DN......DPKTdaIKTTTNQDAIDNAQKEID..KIKA..PNLKKDAQNNLNRAQQLLDE......
A0A099WBG6_9LIST/141-201               ......agke-------AAVNKLFI.DN......NPTN.tIRDTLVQADIDQAENIAN..SVTD..ATLKATLQDRVASANQQLQ-d.....
A0A099VYR1_9LIST/355-418               ........ar--QEAADASVKNLFN.NN......DVNG.tIKDTTNQKAIDDAKKLVD..AVTD..PTKKAELENILKEAQDQLDA......
C0ZKG4_BREBN/394-457                   ........pa--LLKAKRAVEELFT.DG......KKEE..LREGTTQKQIDDAKKLVE..GLDN.sVQEKPGLLADIEKAQDQYDD......
A0A1L8WHM8_9ENTE/42-106                ........pd--VQKAIDAVNALFT.DN......THTA..LAPTTTSQSIKDAKKLVT..KILTvnRSYALELGKLCMKATDLLN-k.....
A0A5R9E0Y8_9LACT/47-108                .........e-RLQAAQEDISILFE.DQ......NNQV..LRSDVTQEEIQQAEISAN..KLPS..-DSREELNNTVDEAQAQF--ev....
A0A099VYR1_9LIST/648-712               ........as--EEAAKKAVDELFQ.GN......NPSTgvIKETTDQGAIDAAQDLIN..KVTD..PTIKKDLQKELDKAQDLL--ae....
A0A099WKL4_9LIST/491-552               .........a-DQDAAKKAIDALFT.DG......TKTD..IKPTTDAEAIKNAQDLLD..KVQD..PTVKETLQKDIDKAKELL--a.....
A0A6G7XXI4_9FIRM/486-546               .......ali---NDATTKVNALF-.EA......DGIT..IKETLTQTEIAAAQTAVN..LLDD..SEVKTELQGQIDNAKEQL--v.....
A0A1L8W7E4_9ENTE/279-338               .........p--IKQATRAVNQLFN.GN......T---..PKESNTQEKIDSARKKVE..AIKG.hATVKAKLLEKVKIAQAALD-n.....
A0A099W4G4_9LIST/232-295               .......ale---QQAQQAVNNLFN.GS......NPAN.vIKTGLTQAEIDAAQNLVN..QVTD..ETKKAAFQKNLDNAKKQLND......
A0A291BZB5_BROTH/400-462               ......detn----KAEENVNNLFA.DK......EHTT..LAEGVTQKDIDAAKEAAN..KVTD..KAKKEELLNEIQKAQDLL--ta....
C0ZKG4_BREBN/460-521                   ........lv----EAKKAVRDLFT.DS......NQAA..LKPEVTQSTIHAAKEKVD..KLKD.gSEAKVLLLADIQKAQELFD-l.....
Q38Z85_LACSS/161-223                   ..........KAQQAAMTAVDNLFT.NS......DHTA..IPATLTTEDFTYSKALVE..KTTH..KKFKERYLKLIKEAKAQFDS......
A0A099WGA3_9LIST/557-620               .........a-AQNKAREAVNNLFA.NQ......NPTG.dTKAGLTQAEIDAAQALID..QVTD..PAKKAALQADLNKAQTQLDA......
A0A099VYR1_9LIST/211-272               .......sdk-----AEASVKALFN.NN......DVKG.tIKDATNQKAIDDARTLVN..AVTD..ATKKAELEKNLKEAQEQLDA......
A0A1E5H317_9ENTE/216-278               ...havdesk-------ALIEDLFT.DS......THTA..IKLSTTQLKINKAKALAS..EVLN..ETLKANYLKEITKAQNLLN-k.....
A0A099WKL4_9LIST/550-611               ........ll-----AKKAVDELFK.NN......DPTSnaIKDTTDDQAIKDAKKAVD..ALEP..GAVKDGLTSDLEKAQLLLDA......
A0A099VYR1_9LIST/427-491               ........ar--EEAAEKAVNELFI.ND......TPASntLKNTTDQKAIDDAKNLVN..AIQD..ETKKAELLEKLDKAQDLLNE......
A0A099WGN8_9LIST/410-472               ........de--QDVAKSAVDALFT.DS......TKTG..IKTTTDQAAIDAAKDLVN..KVSD..PTVKADLQKDIDKAQSLLDA......
A0A099WGA3_9LIST/417-480               ........ea--EDKARVAVNNLFT.SQ......NPAN.dAKAGLTQAEIDAAQALVN..EVTD..AKNKAALQADLDKAQLQVN-a.....
A0A099WGN8_9LIST/482-546               .........a-KQDAALKAVNELFN.SN......TPLTdaIKPTTDQAAIDAAKALVN..AVTD..PTVKAALQKDLNRAQELLDA......
A0A1L8WCY4_9ENTE/563-625               ........ny--LKEATEAVNRLFQ.EN......DPTK..IKTNLMQKDLDQVKQKVT..ALPD..SSQKQALLTKLDQAFNQLQ-e.....
A0A371IS10_9FIRM/593-655               .........e-KVKAATEEVNGLFT.DE......SKKA..LKSEVNEEKIAGAEVLVN..GLKN..GEVKNNLIKEIGAARNLLK-a.....
A0A2X3IL40_9LIST/112-175               .....kevel-----SKQNVAALFT.DE......TKRS..LAQHVTKDKLDGVKQAVL.nSTPQ..AKTKLELKRDVEKAYQLL--as....
A0A099WEU3_9LIST/334-397               ........qr--EAEAKAATNGLFV.DN......DATK.gIKPSTDQAAIDVAQAKID..LVTD..ATVKAELQAELDKAQAELDA......
A0A2U3AJ91_9BACL/65-127                .........a-AVKEATQKVNGLFQ.DD......KQQT..IKENLVEAHINSVEPFVN..KITD..GAEKIALQALLVKAQQQ---vad...
A0A1X7LPV4_9BACL/584-646               .........a-ALQAAAEAVNGLFT.DS......TKTA..LKAGVDQAAIDAAKAKVE..LVAD..GADKSALKKAIEIAQDLL--sq....
A0A099W4G4_9LIST/510-573               .........e-AQDAAKASVNDLFL.NN......DPTK.dIKATTNQAAVNAAQEKVN..TVTD..PAVKEALQKQVDKAQAQ---vsa...
A0A0R2J1D4_9LACO/44-106                ..........SKLSVAKEDVEVLFT.DS......SMKQ..LDKRTEKSSITAVDKEVK..KLPS..STEKSKLSKDVEKAKQQFNR......
A0A3D8TTR9_9LIST/225-287               .......qgv---DEARVGIDELFR.DE......THTK..LRLSVVQGDIDAVQKQIN..VILD..PALKQEYQVELDKAQRLMDE......
A0A099WGA3_9LIST/627-690               .........a-AQNKAREAVNSLFA.SQ......NPAN.dAKAGLTQAEIDAAQALID..QVTD..PAKKAELQADLNKAQEQIDA......
A0A099WD64_9LIST/225-289               .......kef---NTANGAVSDLFV.NN......LQTSgaIKSTVTQSAIDAAKALVN..QLTD..SPQKTALLANVQLAQNLL--ts....
Q7AP83_LISMO/141-198                   .........i------QTAINELFL.NN......NPTG.tILTITDQNAINAVQEQIN..TVTS..-SEKESFQEQLNNAQQQLDA......
A0A099WBG6_9LIST/269-328               .........a--EQEAAIAVASLFT.E-......-SHE..IVADLTQDRIDQAQLKVN..AVTN..PEKKAQLQEQINDAQQQLD-n.....
A0A6M1UA04_9BACL/844-908               .........a-ALQEAQQAVTALFA.DY......STKA.aLAANVDQAAINAAKAKVD..ALND.sVTEKASLLADIQTAQDLLDA......
W7CZ22_9LIST/546-608                   .........a-DMKAAQEATDALFA.DK......EHTL..LADNATQEMIDSAKELAD..KLPV..GKDKEVLKEEIANAQTLLDE......
A0A1D2LBQ7_BROTH/727-789               ........ah--LAATQDAVENLFT.GP......NHTA..IKSTTDQREINDVQALVN..AVAY..PEEKAKLQAEVDKAQDFL--tn....
V7HSW9_9LACO/267-331                   qtavtttllp--------EVEALYT.DS......SHTT..VKPSLTQAQLEAAQSLVD..RIEN..PAIKQLNQALITQAQ-----pdvee.
A0A099W4G4_9LIST/440-503               .........e-AQDKANEAVTNLFE.NN......DPDG.dIVGNLTQDDLDKAQDLIN..KVTD..ETKKAELQSSLDKAKQQL--ad....
A0A1E5GZU7_9ENTE/207-267               ...lkqvkpy---------VDELFT.DE......THTE..LKSSVTQKKINEVKKIVN..TLST..TSDLNLLTAEVSKAQALLN-k.....
W7CZ22_9LIST/477-540                   ..........QQIEIAKAAVDVLFA.ND......AHTE..LAIEATQAMIDKAQEILD..NTTM.tVTVHQKLTADIQTAQTLLNE......
A0A099W9V9_9LIST/586-650               ........ar--QEAALKAVNELFN.SD......QPSTdaIKDITNQEAIDAAQKLVD..AVTD..PSVKAALQKDLDRAQELLDA......
A0A099WI22_9LIST/204-267               ........ak---TMASNAVMALFQ.NN......NPTSntLNPATTQKTIDYAQSLIN..VVQT..AAVKASLQQELDKAQSLLNA......
A0A291BZB5_BROTH/272-334               ......detn----KAEENVNNLFA.DK......EHTT..LADGITQKDIDVAKEAAN..KVTD..KAKKEELLNEIQKAQDLL--ta....
A0A6M1UA04_9BACL/1041-1105             .........v-ALEAAQQAVAALFA.DY......STKA.aLAANVDQAAINAAKAKVD..ALND.sVTEKAGLLADIQAAQDLLDA......
A0A1D2LBQ7_BROTH/525-587               ........rh--QEAATAAIEALFT.DD......THEA..IGKDVVKETIDAATELVS..KVTD..ADKKAEYTEQIKIAQELLD-t.....
K8E1J7_CARML/209-271                   ..........QNIIEARRDVEQLFT.DT......SYTK..LNEFVTQKELDNVKKTVD..LVVN..STERAFLLQYTNLAQEFLDA......
A0A099W9V9_9LIST/733-797               ........ar--QEAALKAVNELFN.SD......KPSTdvIKDTTTQATIDAAQKLID..AVTD..PAVKAALQKDLNRAQELLNE......
A0A3M8DYS1_9BACL/840-902               ........qi--VQATKDAVAALFT.DA......NKTA..LAVGVDQTKVDSAKTKVN..ALSD..ATLKASLLTDVAKAQDLLDQ......
A0A099WEU3_9LIST/265-328               .......tgt---SEAKAATDALFV.DN......DPTK.dIKPTTDQAAIDAAQAKID..NVTD..ATAKAELQAELDKAQAAIDA......
A0A099VYR1_9LIST/572-636               .........g-QQLIANFLVNQLFQ.DN......DPATdeIKDITNQLAIDTAQSQID..LVKV..STVRDSLQKTLDRAQELLDA......
W7CZ22_9LIST/682-744                   .........a-DLKAAQEATNNLFG.DE......SKTI..LGEQTSQEMIDSAKELIN..KLPE..GKDKENLVADIAKAETLLK-a.....
A0A6M1UA04_9BACL/910-974               .........v-ALEAAQQAVAALFA.DY......STKA.aLAANVDQAAINAAKAKVD..ALND.sVAEKASLLADVQAAQDLLDS......
A0A099WGA3_9LIST/487-550               .........e-AQNKARAAVNDLFA.SK......DPTG.dVKTGLTQAEIDAAQVLVD..KVTD..PAKKAELQADLDKAQQKLDA......
A0A3S0BMP8_9BACL/161-223               .........e-KISTATKLVEGLFT.SS......EKST..VKENITRAEIDEAKAKVN..EIKQ..DKAKESLLTSIQTTDAFLE-s.....
A0A099WGA3_9LIST/697-760               ........aa--QDKARAAVNNLFA.NQ......NPTG.dTKTGLTQAEIDAAQALID..QVTD..PAKKAELQADLNKAQTQLDA......
A0A099VYR1_9LIST/722-786               ........ar--EEAAKNAVDELFQ.GN......NPSTgiIKETTDQSVIDAAQDLIN..KVTD..PTIKKDLQKELDKAQDLL--ae....
Q38XP9_LACSS/83-143                    ..........KKLDDAKLNVDGLFS.DA......KHTK..LVHGISHKDIKSVSEDVD..ALKD..SKTKDTLKKDILKAEKL---w.....
A0A291BZB5_BROTH/336-398               ......detn----KAEENVNNLFA.DK......EHTT..LADGITQKDIDVAKEAAN..KVTD..KAKKEELLNEIQKAQDLL--ta....
N0AVQ0_9BACI/172-234                   .........n-TIKTAKEKLSALFT.DL......ETST..VKDDITRDMFNDAKSSID..SIKN..KKVKESFASLIAKV------dsslts
F9UPV7_LACPL/48-110                    ..........QKLEDATTDVDSLFS.DS......GHTA..LVPGTKKLLIDEVSKEVN..KLTD..SKGKSNLQKELKNAYVLY--pk....
A0A1D2LBQ7_BROTH/659-721               .........h-NQEAATIAIDKLFA.DD......THSQ..MHPDLTQKQIDEAQALVD..KVKD..AEPLAKFTAEIKAAQKFLD-i.....
A0A6G7XCX1_9MICO/275-333               ........ld-----ATLDVDGLF-.KA......DKVT..LQDGVKQADIDRVKGLVN..EMDD..SPVKTALLQRIAEAQRQLD-i.....
W7CZ22_9LIST/349-411                   .......aah---EKAKAAIAALYA.DE......KQTS..IHGKLTQDMIKSALALTN..ELPM..SDVKTSYLEAIVKAQEQYD-l.....
#=GC seq_cons                          .........t...ptAppAVssLFs.ss......s.ss..l+ssssQssIDuApshVs..tlsD..sstKspLppcls+AQphLs.......
//
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