GenomeNet

Database: Pfam
Entry: FKBP_N_2
LinkDB: FKBP_N_2
Original site: FKBP_N_2 
#=GF ID   FKBP_N_2
#=GF AC   PF18023.2
#=GF DE   BDBT FKBP like N-terminal 
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF AU   Smart A;0000-0002-6965-5633
#=GF SE   ECOD:EUF03040
#=GF GA   27.00 27.00;
#=GF TC   27.00 27.00;
#=GF NC   26.90 26.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   24210908
#=GF RT   Noncanonical FK506-binding protein BDBT binds DBT to enhance its
#=GF RT   circadian function and forms foci at night.
#=GF RA   Fan JY, Agyekum B, Venkatesan A, Hall DR, Keightley A, Bjes ES,
#=GF RA   Bouyain S, Price JL;
#=GF RL   Neuron. 2013;80:984-996. 
#=GF DR   INTERPRO; IPR040478;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This is the N-terminal domain of the beta chain found in
#=GF CC   Drosophila melanogaster protein BDBT (a FK506-Binding Protein)
#=GF CC   which stimulates the DBT circadian function. The domain contains
#=GF CC   the DBT-binding site. The domain is structurally homologous to
#=GF CC   the peptidyl prolyl isomerase (PPIase) regions of FK506-binding
#=GF CC   proteins despite low sequence homology. BDBT is structurally
#=GF CC   related to the immunophilin FKBP51 and it shares a common domain
#=GF CC   organization consisting of PPIase-like and TPR domains with
#=GF CC   noncanonical immunophilins such as FKBP38 or FKBPL [1].
#=GF SQ   84
#=GS A0A482VXM4_9CUCU/281-367  AC A0A482VXM4.1
#=GS K7IUU4_NASVI/4-120        AC K7IUU4.1
#=GS T1GYE6_MEGSC/10-113       AC T1GYE6.1
#=GS A0A3B0KEE4_DROGU/9-119    AC A0A3B0KEE4.1
#=GS A0A151X9K9_9HYME/5-126    AC A0A151X9K9.1
#=GS A0A1B0BXT8_9MUSC/1-116    AC A0A1B0BXT8.1
#=GS A0A182G133_AEDAL/240-311  AC A0A182G133.1
#=GS A0A401PHI2_SCYTO/40-151   AC A0A401PHI2.1
#=GS A0A402FGR6_9SAUR/65-149   AC A0A402FGR6.1
#=GS A0A0M4EP15_DROBS/9-137    AC A0A0M4EP15.1
#=GS A0A182MHJ5_9DIPT/1-48     AC A0A182MHJ5.1
#=GS B4JFI6_DROGR/9-113        AC B4JFI6.1
#=GS A0A182VR95_9DIPT/335-440  AC A0A182VR95.1
#=GS A0A182F7A2_ANOAL/345-448  AC A0A182F7A2.1
#=GS A0A232FA50_9HYME/4-120    AC A0A232FA50.1
#=GS B4KDL5_DROMO/9-115        AC B4KDL5.1
#=GS A0A0L7QTU7_9HYME/6-121    AC A0A0L7QTU7.1
#=GS A0A1A9VVX2_GLOAU/13-124   AC A0A1A9VVX2.1
#=GS A0A182TV20_9DIPT/1-87     AC A0A182TV20.1
#=GS A0A0L0CM86_LUCCU/13-120   AC A0A0L0CM86.1
#=GS A0A067RVR2_ZOONE/3-121    AC A0A067RVR2.1
#=GS A0A182P2G3_9DIPT/301-406  AC A0A182P2G3.1
#=GS A0A0L8I5K3_OCTBM/8-120    AC A0A0L8I5K3.1
#=GS A0A2P8YGL9_BLAGE/11-128   AC A0A2P8YGL9.1
#=GS A0A182HKS3_ANOAR/1-87     AC A0A182HKS3.1
#=GS A0A195C9I9_9HYME/5-125    AC A0A195C9I9.1
#=GS A0A423TXR8_PENVA/17-120   AC A0A423TXR8.1
#=GS F4X8E6_ACREC/1-100        AC F4X8E6.1
#=GS A0A1U7S8D3_ALLSI/84-172   AC A0A1U7S8D3.1
#=GS A0A2A4IY96_HELVI/9-122    AC A0A2A4IY96.1
#=GS B4GEK7_DROPE/9-119        AC B4GEK7.1
#=GS A0A1S3JRE7_LINUN/15-129   AC A0A1S3JRE7.1
#=GS A0A1W4VLZ5_DROFC/9-114    AC A0A1W4VLZ5.1
#=GS Q9VDE4_DROME/9-119        AC Q9VDE4.1
#=GS Q9VDE4_DROME/9-119        DR PDB; 4IT6 A; 9-118;
#=GS Q9VDE4_DROME/9-119        DR PDB; 4IT4 F; 9-119;
#=GS Q9VDE4_DROME/9-119        DR PDB; 4IT4 C; 9-119;
#=GS Q9VDE4_DROME/9-119        DR PDB; 4IT6 B; 9-118;
#=GS Q9VDE4_DROME/9-119        DR PDB; 4IT4 B; 9-119;
#=GS Q9VDE4_DROME/9-119        DR PDB; 4IT4 D; 9-119;
#=GS Q9VDE4_DROME/9-119        DR PDB; 4IT4 A; 9-119;
#=GS Q9VDE4_DROME/9-119        DR PDB; 4IT4 E; 9-119;
#=GS A0A1X7VPK3_AMPQE/1-95     AC A0A1X7VPK3.1
#=GS A0A401STF4_CHIPU/35-146   AC A0A401STF4.1
#=GS A0A2B4RG75_STYPI/6-110    AC A0A2B4RG75.1
#=GS W5JJ68_ANODA/340-442      AC W5JJ68.1
#=GS A0A154P472_DUFNO/6-121    AC A0A154P472.1
#=GS A0A194RHK2_PAPMA/9-120    AC A0A194RHK2.1
#=GS R7TMP0_CAPTE/13-130       AC R7TMP0.1
#=GS A0A0J7KC95_LASNI/4-122    AC A0A0J7KC95.1
#=GS A0A1B0FM95_GLOMM/13-124   AC A0A1B0FM95.1
#=GS A0A194PFQ6_PAPXU/9-120    AC A0A194PFQ6.1
#=GS A0A3S2M2Y9_CHISP/9-122    AC A0A3S2M2Y9.1
#=GS A0A151J954_9HYME/5-124    AC A0A151J954.1
#=GS A0A2C9LCL0_BIOGL/30-157   AC A0A2C9LCL0.1
#=GS H9IU71_BOMMO/9-122        AC H9IU71.1
#=GS A0A158NBV8_ATTCE/5-126    AC A0A158NBV8.1
#=GS A0A2T7NLF7_POMCA/52-142   AC A0A2T7NLF7.1
#=GS C3Z4W5_BRAFL/31-140       AC C3Z4W5.1
#=GS A4S4I9_OSTLU/243-334      AC A4S4I9.1
#=GS E0VUN3_PEDHC/8-104        AC E0VUN3.1
#=GS Q17CG8_AEDAE/8-114        AC Q17CG8.1
#=GS B4LWU7_DROVI/9-115        AC B4LWU7.1
#=GS B3M2V8_DROAN/9-119        AC B3M2V8.1
#=GS A0A2J7R561_9NEOP/11-129   AC A0A2J7R561.1
#=GS A0A182X9U1_ANOQN/1-48     AC A0A182X9U1.1
#=GS B4IKK6_DROSE/9-119        AC B4IKK6.1
#=GS A0A1L8F3P3_XENLA/15-117   AC A0A1L8F3P3.1
#=GS A0A182JPC4_9DIPT/1-102    AC A0A182JPC4.1
#=GS A0A182UUH5_ANOME/23-128   AC A0A182UUH5.3
#=GS A0A195BG58_9HYME/5-126    AC A0A195BG58.1
#=GS F5HMS3_ANOGA/1-87         AC F5HMS3.1
#=GS T1ER35_HELRO/14-128       AC T1ER35.1
#=GS A0A195FDF0_9HYME/5-126    AC A0A195FDF0.1
#=GS B0W8N8_CULQU/1-87         AC B0W8N8.1
#=GS A0A1D1VEV4_RAMVA/18-139   AC A0A1D1VEV4.1
#=GS B4NIQ1_DROWI/9-113        AC B4NIQ1.1
#=GS R4FL77_RHOPR/15-117       AC R4FL77.1
#=GS A0A1A9W9E5_9MUSC/9-120    AC A0A1A9W9E5.1
#=GS A0A212EHB1_DANPL/11-123   AC A0A212EHB1.1
#=GS A0A482XP28_LAOST/10-124   AC A0A482XP28.1
#=GS E2AR15_CAMFO/4-122        AC E2AR15.1
#=GS A0A0N0BHV3_9HYME/6-121    AC A0A0N0BHV3.1
#=GS A0A1I8NUA8_STOCA/13-120   AC A0A1I8NUA8.1
#=GS A0A087T9A1_9ARAC/6-109    AC A0A087T9A1.1
#=GS A0A1A9Z3S0_GLOPL/13-124   AC A0A1A9Z3S0.1
#=GS A0A1I8NGV6_MUSDO/13-120   AC A0A1I8NGV6.1
#=GS A0A182YGG5_ANOST/356-450  AC A0A182YGG5.1
#=GS H3AXW6_LATCH/5-105        AC H3AXW6.1
#=GS W4Y2I6_STRPU/48-175       AC W4Y2I6.1
#=GS A0A2A3ETS3_APICC/99-212   AC A0A2A3ETS3.1
#=GS E2B5K7_HARSA/5-122        AC E2B5K7.1
A0A482VXM4_9CUCU/281-367             rstgqfy-----------ILEGDWG..--KKPSEQSECDVLISD.C..-.---.-.-SDLLLEY--.....-......-NNSTLVIGDSDNYIRRTLDICLTTMNEQEIAKFTIL--.---....----.....---------------penisftlklvric..............................
K7IUU4_NASVI/4-120                   .......WESADKLIKKEIIREG-Q..FSNKPTELSVCTIHVAN.P..Q.SLD.L.SIEQMKENLYs..diId....aDSKKVIVIGDACSHVDRYIERAIEMMSLNEHSLITVQFP.PDR....TRTE.....TIILSLEVTLEKVD-f...........................................
T1GYE6_MEGSC/10-113                  .......WEDTKKGIGKTTISFDSK..HLIAPTEVSKVSVIFSN.V..Q.NLE.N.RKSKFLEK--.....I......DSKVEIQMGSALNPIDFYIEILLGHLKKGELAKCFIKTS.AM-....E---.....---ITFNIKIIEIEN............................................
A0A3B0KEE4_DROGU/9-119               .......WKDEKRGLCKKVLGLQFE..DMAKPMAASTVLFSVNNkC..A.NLK.D.RPSKYLESDEs..stY......PQQHTLEMGTAITPVDCYVEMLLQQLMLGETAACSITSK.TGE....R---.....---IEFELKLEL---ivk.........................................
A0A151X9K9_9HYME/5-126               .......WKSADKSIQKRVLKPGVF..-TKKPTECSTCSIIVEN.I..-.NIS.GmSETDLKEKYHt...nIl...dgELEKTVIIGEASSEIDEKVERVICMMNINERSLVIIAMP.LKQ....SDESidnneSVIVKFEITLSLCK-r...........................................
A0A1B0BXT8_9MUSC/1-116               ......m---PRKGLHKKVLALDFK..RLCKPHLLSTVIVSIEQ.V..L.NLQ.G.RESIYLDDQR.....A......KQDVTIEMGKACTPLDYYLEILVQQMIEGETAECIIETK.I--....----.....---------------lpvvciltlksvleskeiqmlrppei..................
A0A182G133_AEDAL/240-311             .fddsps------------------..-----------------.-..-.---.-.KESNILNNHE.....P......ISEQWITIGSGLTPIDCYIELFLIEMLPNEKSKCTIRCK.DNL....Q---.....---VSFILKLLRVE-t...........................................
A0A401PHI2_SCYTO/40-151              .......WACPDGSFVKKILQRGSG..-LDKAKEGCKCRVCVEV.E..P.SCNfD.AGTHFQN--G.....I......NQTIEMILGESDTQFAEIIEKCVETMLLGEQCEVLLAPE.LME....KFTD....cGTRLKLYVKLEEFT-f...........................................
A0A402FGR6_9SAUR/65-149              .......WACPDGTFVKRVLEAG-Q..GVDKPKEGSLCQVFIEA.Q..-.---.-.-PSGLLSYPS.....-......HSWAEVELGAGNAEWDGAVDRCLETMLAGERAELRL---.---....----.....---------------aggds.......................................
A0A0M4EP15_DROBS/9-137               .......WTDATRGLHKKVLNLNLQlhCVEKPLAISTLIFTVNK.S.cA.NLG.D.RPSKYLANND.....-......ESQHEMEMGTAVTPIDCYLELLMQQFIAGETSACSIKTK.SGD....T---.....---LQFELKLE----livintqietlkgaelhklalqyk....................
A0A182MHJ5_9DIPT/1-48                .......------------------..-----------------.-..-.---.-.----------.....-......-------MGTALTPVDSYVEQLLQQMSMNEESKCTITDA.QGN....D---.....---ITFTMKLLRIEN............................................
B4JFI6_DROGR/9-113                   .......WSDEMRGLHKKVLSLDFQ..TVEKPLAVSSVLFTVNK.S..-.CVG.S.RPTKYLNCAE.....-......MQQHAMKMGSAVTPIDCYLELLLQQFLPGETAVCSIATK.TGE....Q---.....---LEFELKLDRIT-s...........................................
A0A182VR95_9DIPT/335-440             ......y-EDRTKGLRKERLSFRFT..TAEKPSVLCRCLVTISD.V..G.ATG.T.HETNYLTTGS.....-......TTERWITMGTALTPVDSYVEQLLQQMLTNEESKCTITDA.YAN....D---.....---IVFTMKLLRIE-d...........................................
A0A182F7A2_ANOAL/345-448             ......y-EDRAKGLRKERLSFKLT..TVEKPTELSRCLVAVYD.V..L.NVE.A.HQTEYLTGT-.....-......-GERWITMGTAVTPVDCYVELLLQQMLPNEESRGTIHTK.NHG....D---.....---ISFTMKLIRIE-g...........................................
A0A232FA50_9HYME/4-120               .......WESADKLVKKEIIREG-Q..FSNKPTELSVCTIHVAN.P..Q.SLD.L.SIEQMKEDLHs..diId....aDSKKVIVIGDACSHVDRYIERAIEMMSLNEHSLITVQFP.PDR....TRTQ.....TIILSLEVTLEKVD-f...........................................
B4KDL5_DROMO/9-115                   .......WSDAARGLQKKVLSLEFQ..RVEKPLLVSTVAFTVKK.P.cA.NLG.S.RPTKYLASKE.....-......PQQYTLEMGSADSPIDCYIEILLQQFVIGETSACSITTK.TGE....C---.....---LEFELKLDRI--vs..........................................
A0A0L7QTU7_9HYME/6-121               .......WESVDRIVRKDVIKSG-Q..YSKKPSESAKCEVIVEN.I..Y.VVN.A.SVEDLKEKFNs...eIl...nnVGEKTVIIGEANCEIDRQIERVIEMMMVLEKSLITLNIL.LEG....I-DM.....CLIIKFEITLTEMQ-p...........................................
A0A1A9VVX2_GLOAU/13-124              .......WKMPRKGLHKTVLALDFK..SLSKPHVLSKVIISIQE.V..Q.NLQ.G.RESMYLDDQK.....A......EQDVTMEMGKACTPLDYYLEILVQQMIEGETAECIIETK.TGK....T-VC.....ILTLKSVLESKK---iqm.........................................
A0A182TV20_9DIPT/1-87                ......m------------------..--EKPSELSRCLVTISD.V..S.NVE.V.HESSYLGGGS.....-......SEELWITMGTALTPVDCYVELLLQQMLTNEQSKCTISSA.KRG....D---.....---VTFTMKLVRIE-g...........................................
A0A0L0CM86_LUCCU/13-120              .......WKLERKGLYKKVQALEFT..KVEKPHQVAKVIINVEQ.V..E.NLK.D.RETQWLNANT.....L......NKDQIMEMGSALTPIDYYLEILVQQMMLGETAECTIKTK.TPG....E---.....--DIKIVLTLQEIKQ............................................
A0A067RVR2_ZOONE/3-121               ..nsqsi------LCHKEIITQGVW..-GDRPREGGKCTVIIDD.I..V.TEN.I.ALDEVQHATMsiylgL......EFNGSLIIGDSDTDIDRSLERCIQAMLHMEVSMIILTFP.PKL...cSETSl...kTRTVKCKVHLKEIH-n...........................................
A0A182P2G3_9DIPT/301-406             ......y-EDPSKGLRKERLSFRFT..SAEKPSELSRCLVTISD.V..S.NVE.A.HETSYLIDTS.....-......TEERWITMGTALTPVDCYVELLLQQMLTNEESKCTISCT.KTN....S---.....---ISFTMKLLRIE-g...........................................
A0A0L8I5K3_OCTBM/8-120               .......WTSPNNSISKEILKFGSG..-LARPTDGSICIVSISH.I..G.GAT.L.NKDS-LGY-G.....L......GENVKIQIGEGDTILGELIDECLESMKLDECCEATFHIL.LES....SKDSc..dqFEKYKFQLELHKFEN............................................
A0A2P8YGL9_BLAGE/11-128              ..wstis-------WRKEVITAGLW..-GSRPREGAKCVVEIEK.I..C.VVN.V.TLEQ-VQQLD.....IslylssDFNKTLVIGEADTDFDRCFNRVMRTMQKGEVSSFIFSFL.LSD....SND-.....---------------ienskegtitcivllkeff.........................
A0A182HKS3_ANOAR/1-87                ......m------------------..--EKPSELSRCLVTISD.V..S.NVE.A.HESSYLGGGS.....-......SEELWITMGTALTPVDYYVELLLQQMLTNEQSKCTISSA.KRG....D---.....---VTFTMKLVRIE-g...........................................
A0A195C9I9_9HYME/5-125               .......WKSADKSIQKRVLQPGIF..-TKKPTECSTCTINVEN.I..-.NVT.G.MSEMDLKVKYh..tnIl...dgEPEKTMVIGEASSKIDEKIERVICMMNINERSLVIIAMP.LKQ....SESIdn.neSVIVQFEITLSLCK-r...........................................
A0A423TXR8_PENVA/17-120              ewayngk------------------..--SAPRDGSKICVHITN.E..-.CCS.C.EIEL-LESRY.....Lv....cEAEETVVFGEAVSAFDRSLELALSVMNDDETALINIKLP.RKY....VDDEad.ndDITFTCQLGLK----iien........................................
F4X8E6_ACREC/1-100                   ......m------------------..------ECSTCTIIVEN.I..N.IIG.M.SETDLKEKYYt...nIl...dgESEKMMVIGEASSEIDEKIERVICMMNINERSLVTIAMP.LKQ....SDESvdnneSVIVKFEITLILCK-r...........................................
A0A1U7S8D3_ALLSI/84-172              .......WTSPDGAFTKLVLEAGHG..-LARPTLGCRCQVLLQA.P..P.G--.-.---TSLSYPT.....-......GHWAEIQLGHGPTAWDDLVDACLESMAAGERVQL-----.---....----.....---------------qaqaggtvdvs.................................
A0A2A4IY96_HELVI/9-122               .....sr---PDREIRKKVIKPGDY..-TLVPYEDSRCKITLTD.V..K.CTN.E.AGNCEIEPIS....rIf...srSFDGNVLIGDCDSFIDKDFELVLQQMCCGEVCEATMVYR.NKD....G-AL.....VKQISCQVELKELT-e...........................................
B4GEK7_DROPE/9-119                   .......WKDEKRGLSKKVLSLEFA..DMAKPMAASTVLFSVNNkC..A.NLE.D.RPSKYLGGEE....sLt....fPQQHTLEMGTATTPVDCYVEMLLQQFMPGETAACSITSK.TGE....R---.....---IEFDLKLD----livk........................................
A0A1S3JRE7_LINUN/15-129              .......WVSPDRSICKQITHPG-E..GLYTPNEGSIVTVCIKS.V..H.IPQ.D.VAAGQLYQYD.....-......CGNIEITLGFPDTWCNENIEKCIESMKPGEVCEVCFSRD.HKTwdefKDDE.....ASKVVLRVTLKSVQ-r...........................................
A0A1W4VLZ5_DROFC/9-114               .......WEDKSRGLTKKVLSLQFT..ELEKPTTVSTVEFSVTKkT..A.NLG.G.RPSKYLANNE.....-......-AKHTLEMGTSLTAVDCYLELLLQQFVPGETSACSITTK.TGE....R---.....---IEFELKLERI--vr..........................................
Q9VDE4_DROME/9-119                   .......WEDKNRGLAKKVIGLQFT..EMDKPTIISTVEFSVNKkA..T.NLG.G.RPSKYLVSDEs..atY......PQKHSLEMGTSLTAVDCYLELLLQQFVPGETAACSITTK.TGE....R---.....---IEFELKLEKI--vk..........................................
#=GR Q9VDE4_DROME/9-119        SS    .......EEETTTTEEEEEEEE--S..GGGS--TT-EEEEEEESEE..B.S-T.T.---SST---TT..--S......SEEEEEETT---SHHHHHHHHHHTT--TTEEEEEEEE-T.TS-....E---.....---EEEEEEEEEE--EE..........................................
A0A1X7VPK3_AMPQE/1-95                .....ma--------AKRILKEGAG..-LYKPNERALVTVTVKC.W..E.EET.K.VTDEPFT---.....S......KENHQIVLGEPENILWYKLERTIMNMKEGEEIEVLLNVN.EK-....----.....---------------dilcriellsfk................................
A0A401STF4_CHIPU/35-146              .......WTCPDGSFVKKILQRGSG..-LDKPKEGSKCRVCVDV.E..PsSSF.D.AGTHFQN--G.....I......NQSVELILGETDTQFVELIEKCVETMLLGEQCELIPVPD.LMK....TFTD....cREGLRMVVKLEEFT-l...........................................
A0A2B4RG75_STYPI/6-110               .srvsal--------PRTITRKG-T..GLETPNYGSSCHIKLKI.F..-.---.P.PDGTVLHN--.....-......-AQKKVVIGEGDSEVSETLDKCLECMHAQEICLIPFDNE.DLC....QELGi..vyERDLKCEIEL-----lsfsk.......................................
W5JJ68_ANODA/340-442                 ....mnr----AKGLRKERVSFQLT..SVEKPSELCRCLVTVYD.V..H.NVE.A.HQTEYLTSTD.....-......--ERWITMGTAVTPVDCYVELLLQQMLPNEESRCTIQTK.QHG....D---.....---ITFTIKLIRIE-d...........................................
A0A154P472_DUFNO/6-121               .......WESADKIVRKDVINPGFF..-LWKPTECASCGVLIEN.I..Q.VVN.T.SADDLKEKFNs...tIl...dgTNEKTLVIGEANCEIDCHIERAIQMMNIHEKSVVTLNIS.LEN....N-DK.....PLIIKFEVTLTKME-p...........................................
A0A194RHK2_PAPMA/9-120               ......t--RPDREITKKIITPGDY..-SIVPYEESRCKIVLSN.V..T.NTI.E.DVERDVESRI.....Ls....kNFDGVVIIGEADSFIDKDFELILQQMCCGETCLARIVYK.NQN....CE-I.....VKEISCEIELKEVT-e...........................................
R7TMP0_CAPTE/13-130                  .....ye--PEDKSFSKHVIQEGTG..-DTSPNEASVCTVLVDP.M.gQ.SVT.P.AIEAALGNYK.....I......GDRCEVTIGESTTFLAELLDKVLMSMKEGETAYVKSKIN.SDG....QKMDsfgvnDAAFKCNVSL-----femsr.......................................
A0A0J7KC95_LASNI/4-122               .......WKSADKSISKNVLKPAIY..-TKKPTERSTCNVLVEK.L..-.NVT.G.ASDEDLREKYh..teIl...dgEGEKVLVIGEASAEIDRKIESAIHMMNIHERSLVTITIP.AKQ....SEVNn...rSITVKFEITLIKCER............................................
A0A1B0FM95_GLOMM/13-124              .......WKMPRKGLHKTVLALDFK..SLSKPHILSKVIFNIQE.I..Q.NLQ.G.RESMYLDDQK.....V......KQDVTMEMGKACTPLDYYLEILVQQMIEGETAQCIIETR.TGK....T-VC.....ILTLKSV--------leskeiqm....................................
A0A194PFQ6_PAPXU/9-120               ......t--RPDREITKKIITPGDY..-SIVPYEESRCKIELSN.V..R.HTN.E.DVNIDVESRI.....Ls....kNFDGVVIIGEADSFIDKDLELILQQMCCGETCFARIVYK.NQN....CE-I.....VKEISCEIELKEVT-e...........................................
A0A3S2M2Y9_CHISP/9-122               ......s--RPDREIKKKIITPGDY..-TLVPYEDSRCKIVLSH.V..T.CTN.-.SLGKCEIEPEs...rIf...skEFDGNVLIGDTDNFIDKDFELILQQMCCGETCEASLLYR.DSE....-GVL.....VKEIKCNIELKEVT-d...........................................
A0A151J954_9HYME/5-124               .......WKSADKSIQKRVLKSDVF..-TKKPTECSTCTIIVEN.I..N.VTG.M.SETDLKEKYHt...nIl...dgESEKTVVIGEASSEIDEKIERVICMMNINEKSLVTIAMP.IKQ....SDESv..dnNESVKFEITLALCK-r...........................................
A0A2C9LCL0_BIOGL/30-157              .......WLTADLTVKKTVTKKG-K..AFLRPQLESVCVVSVDY.N..D.N--.E.TSDHCKEL-Y.....MfltqhaRNRLELKLGSADSKYMLGLEKLLMTMTESEECLFIISSC.HGS....E-EG.....DII--LKVTLHSF--tvekpiwqmsskekysla..........................
H9IU71_BOMMO/9-122                   ......s--RPDRVIRKKLKNPGDY..-TIVPYEDSRCKIKITN.L..A.CTN.HlGKCEIEPESK.....Vf...stNFDGNVLIGDSDFFIDKDFELILQQMCSGETCEVNMVYR.DGS....G-EL.....VKEISCDVELKEVT-e...........................................
A0A158NBV8_ATTCE/5-126               .......WKSADKSIQKKVLKSDVF..-TKKPTECSTCTIIVEN.I..-.NIT.G.MSEMDLKEKYh..tnIl...dgESEKMIVIGEASSEIDEKIERVICMMNINERSLVTIAMP.LKQ....SDESvdnneSIIVKFEITLVLC--kr..........................................
A0A2T7NLF7_POMCA/52-142              ....hlt-----RVCEKRLLQKG-Q..GLSSPVPGASCKISLQI.A..G.GTC.E.CDAQSLGYPS.....-......-GESSVQIGEGDTRLSSIIDIALLRMKRGEII-------.---....----.....---------------hfsckdtgtkcs................................
C3Z4W5_BRAFL/31-140                  .......WQAPDQSFAKYILEKG-R..GIETPNLGASCVVQILP.L..-.-VS.E.GLEQGLVGYP.....M......YEENEIVLGEGDTEISEVLDACFETMQAAEVCEVEVAKE.TVG....MGTG.....DDPIRFQLELKEFTR............................................
A4S4I9_OSTLU/243-334                 ...gveg-------ATKKILEEG-E..GYETPNDGAKCEIEYEK.R..-.-VG.G.ATTETKPA--.....-......---HEIVVGD--EHVPDELESAIAMMKLNEKALVKLADG.TEY....T---.....---------------vkmtklerake.................................
E0VUN3_PEDHC/8-104                   ...eist------EIEKKIIKKGKQ..-GKRPFLTWNCRIEIIL.N..-.-ET.Y.DNDNFKT---.....-......-GVIDIVIGYGCNSYDRLIERCVETMHLDEESLFVIKSV.DNV....N---.....---------------dlkvtiilisyl................................
Q17CG8_AEDAE/8-114                   .......WRNDVKGLRKELISFRFI..SLDKPTLESRCLIKVSE.V..S.DLA.S.KESKILIQCE.....T......IPEQWVTIGSGLSPIDCYVELFLMEMLPNEKSKCTITCK.DHL....Q---.....---ISFVLELLQVE-t...........................................
B4LWU7_DROVI/9-115                   .......WNDTARGLHKKVLSLEFQ..KIEKPFAVSTVLFSVNK.P.cI.NLG.P.RPSKYLGSSE.....-......LQEYTLEMGTAVTPIDCYLELLLQQFIPGESSACSITTK.TGE....R---.....---LEFELKLQRI--is..........................................
B3M2V8_DROAN/9-119                   .......WEDKSRGLAKKVLNLQFR..DMEKPTTASTVQFSVNKkC..A.NLG.N.RASSYLTNDEs..stY......PTQHSLEMGTSVTPVDCYLEILLQQFLPGETAACSIATK.AGE....R---.....---IEFELKLDRI--vk..........................................
A0A2J7R561_9NEOP/11-129              ..sqttv------ICHKEMIAEGVW..-GDRPREGGKCVIIIDD.IvtE.NIA.L.DEIQWAA--As..vyLs....sDFNGSLIVGDSDTDIDRSLERCIRTMLHMEVSLMIVTFV.PKT....LHESs..lkARTVKCKVQLKEIH-n...........................................
A0A182X9U1_ANOQN/1-48                .......------------------..-----------------.-..-.---.-.----------.....-......-------MGTALTPVDCYVELLLQQMLTNEQSKCTISSA.KRG....D---.....---VTFIMKLVRIE-g...........................................
B4IKK6_DROSE/9-119                   .......WEDKNRGLTKKVIGLQFT..EMDKPTIISTVEFSVNKkA..A.NLG.G.RPSKYLASDEs..ttY......PQKHSLEMGTSLTAVDCYLELLLQQFVPGETAACSITTK.TGE....R---.....---IEFEMKLEKI--vk..........................................
A0A1L8F3P3_XENLA/15-117              .......WQSPDGSFIKTILEKGSG..-VDKPKECSICKIFVDP.L..-.SIS.S.ADSCTIKGFSy...pT......GCWFQAELGEGETPLDCLVDQCLETMLSGEVCQVETAK-.---....----.....---------------gmkfklrmasfen...............................
A0A182JPC4_9DIPT/1-102               .......----MKGLRKERLSFQFT..SMEKPSELSRCLVTICD.V..S.NVE.A.LETSYLTGGS.....-......IEERCITMGTALTPVDCYVELLLQQMLTNEESKCTISNA.KGN....D---.....---VTFTMKLLRID-r...........................................
A0A182UUH5_ANOME/23-128              ......y-EDRTKGLRKERLSFRFT..SMEKPSELSRCLVTICD.V..S.NVE.A.HESSYLGGGS.....-......SEELWITMGTALTPVDCYVELLLQQMLTNEQSKCTISSA.KRG....D---.....---VTFTMKLVRIE-g...........................................
A0A195BG58_9HYME/5-126               .......WKSADKSIQKKVLKSDVF..-TKKPTECSTCTIIVEN.I..N.ITG.M.SETDLKEKYHt...nIl...dgESEKMIVIGEASSEIDEKIERVICMMNINERSLVTIAMP.LKQ....SDESvdnneSVIVKFEITLVLC--kr..........................................
F5HMS3_ANOGA/1-87                    ......m------------------..--EKPSELSRCLVTISD.V..S.NVE.A.HESSYLGGGS.....-......SEELWITMGTALTPVDCYVELLLQQMLTNEQSKCTISSA.KRG....D---.....---VTFIMKLVRIE-g...........................................
T1ER35_HELRO/14-128                  ....spd----DNSYSKHILTAGVG..-DSTPNDGSTCLVLLTV.L..D.NNN.I.PEEK-LGGYA.....L......DKETEITIGEGDTVISELLDKILITMKEGEQCYVKSNID.VSG....QKVQkyeldDNNFKFKLTLKTFN-r...........................................
A0A195FDF0_9HYME/5-126               .......WKSADKSIQKSVLKSGVF..-IKKPTECSTCTIIVEN.I..N.ITG.M.SETDLKEKYHt..nvLd....gESEKMVVIGEASSEIDEKVERVICMMNINERSLVTIAMP.LKQ....SDESvdnneSAIVKFEITLVLC--kr..........................................
B0W8N8_CULQU/1-87                    ......m------------------..--KKPSELSRCLVKIGD.V..S.DLG.T.RESNFLKPDE.....P......GNEQWISMGSSVTPIDYYVEQIIAQMLTNERSRCTISCK.SG-....S---.....---VSFVLELLRIE-d...........................................
A0A1D1VEV4_RAMVA/18-139              ...wdfa---SDKTFKKRLIRKG-K..GLFCPRDGSVCQFLITP.L..-.PPT.S.AETLTSRSLRlg.htL......EGLKEIIIGEHDAELDHMLDKIIEHMKAEEVAEFKFNIN.AVE....HT--.....---------------slntevgskakesvliairiell.....................
B4NIQ1_DROWI/9-113                   .......WEDPTRGLTKKVLGLEFS..VMEKPLLVSKVEFKVNK.C..E.NLG.R.RPSKYLND--.....L......ASTHCLEMGTAVTPVDYYIEILLQQFLPGETSACCISTK.SGE....K---.....---INLELKLENI--vt..........................................
R4FL77_RHOPR/15-117                  .......WQSTDKRIRKRILHKGWW..NGSRPVEGSPCMVQIDT.S..D.YED.V.NISE---AYR.....Lp....sTDQFKLIVGEGETEFQRMLDRLLPTMDTFEECLVEYKID.ESV....Y---.....---------------kvkikliqh...................................
A0A1A9W9E5_9MUSC/9-120               .......WEMPHKGLYKKVLAMDYK..KLNKPTILSKVIVNIQE.V..K.NLN.G.RETLYLIDQN.....A......NQDLTMEMSAALTPIDYYLEILVQQMIEGETAQCSLQTK.TDK....I---.....---------------mciltlknileseeiqn...........................
A0A212EHB1_DANPL/11-123              ......r---PEREIRKTILVPGDY..-NLVPYEDARCKIRLGD.V..K.CSN.R.AGPCEIEPESri.fnI......PFDGNVIIGDMDSFIDRDVEILLQRMCSGEISRANLTYK.NSH....G-DL.....IKEITFRIELVDVT-e...........................................
A0A482XP28_LAOST/10-124              .......WQSRDKRIVKDILKSGEY..QMERPKEGSVCTIKVQM.M..N.ETE.E.TEKQSYFQSA.....Iv...ceEFDGKMVIGDADTEFDRAVEKVLQLMDKGEVSKITVKLD.TI-....----.....---------------dcsacayvtlidftvsqst.........................
E2AR15_CAMFO/4-122                   .......WKSADESITKNVLKLTVY..-TKKPTERSTCNVLIDK.L..-.NVT.G.ASNKDLREKYy..tdIl...dgEGEKALIIGEASAEIDRKIENAICMMNILEKSLVTITIP.AKQ....SEDNs...eFIIVKFEITLIKCER............................................
A0A0N0BHV3_9HYME/6-121               .......WKSADNIVRKDIIKPG-T..FCKKPTECSTCEVIIEN.V..N.VTN.A.SVHDLKSKFNs...eIl...nnKSKSTLTIGEANCEIDRQIERAIQMMMVSEKSSVIIDVL.LEG....I-DN.....SLVIKFEITLNEIQ-p...........................................
A0A1I8NUA8_STOCA/13-120              .......WQLERKGLHKKVLEHKFT..KLEKPFPVSKVLISVSN.V..E.NLN.G.RESKYLAADK.....L......DQDQCMEMGTALCPVDYYLELMIQQMIIGEKALCTIRTKePGK....S---.....---IKITLSLKKI--ie..........................................
A0A087T9A1_9ARAC/6-109               ......k--APEKFFSKVIISKGYG..-FHTPQDGSVCKIKVIA.D..-.---.-.-EMNILTSVD.....D......TQTKEIVVGDVDESTDQVIEDCIRTMKEEEECCIKFQHP.CLH....T-DC.....VIPVESSV-------emqdnet.....................................
A0A1A9Z3S0_GLOPL/13-124              .......WKMPRKGLHKTVLALDFK..SLSKPHILSKVIFNIQE.V..R.NLQ.G.RESVYLDDQK.....V......KQDVTMEMGKACTPLDYYLEILVQQMIEGETAECIIETR.TGK....T-VC.....ILTLKSV--------leskeiqm....................................
A0A1I8NGV6_MUSDO/13-120              .......WQLERKGLHKKVLAHDFT..KLEKPHAVAKVVICVEK.V..E.NLN.G.RESIYLSEDK.....L......NKSQSMEMGSALSPVDYYLEMLVQQMVIGEKALCTIKTK.EAG....N---.....--EIRITMSLKEIQ-e...........................................
A0A182YGG5_ANOST/356-450             kepladt------------------..-LWKRSRNHRCLVAIGA.V..E.GVG.T.HEATTYLAAG.....T......TTERWITIGTAVTPVDCYVERLLQEMLTNEESRCTITTR.QGH....D---.....---ITFTMKLIRIE-g...........................................
H3AXW6_LATCH/5-105                   .......WACPDGTFVKKVLERG-T..GVDKPKGGSKCRVLIDM.G..-.-LK.A.GPAPGLSC-P.....L......NCWAELTLGEADTEMDEVVEKCLESMLLGEVCEVAVTHS.E--....----.....---------------aglsfllhlaefs...............................
W4Y2I6_STRPU/48-175                  .......WTAPDGSFSKRIIKKGSG..-FTTPNDGASCQVTISI.V..D.PLE.D.ND---VGY-P.....T......GEQVDIVLGDGCGRFSEAIDACLETMHQGEESELRVF--.---....----.....---------------dehhvesvdqthgsaaaefrseagdgqisngvatfrvtlhsftr
A0A2A3ETS3_APICC/99-212              .......WKSADEIVKKEIINHGIF..-CKKATENASCEVIIEN.I..D.AIN.A.SIEDLSKKFNs...kIl...ngKNKKRLIIGEGNCEIDRQIERALQMMMISEKSLITLNIL.LDD....I---.....NLYVIFEITLIEIQ-p...........................................
E2B5K7_HARSA/5-122                   .......WKSADKSIRKNVLKPGIF..-TKKPTECSICNVLMEN.I..N.IME.T.SEDILKEKYHt...nIf...vsEGEKVLVIGEACAEIDRKVERAIQMMNIYERSLVTIIMP.SQS....EVKS....eSVSVKFEITLTKCE-w...........................................
#=GC SS_cons                         .......EEETTTTEEEEEEEE--S..GGGS--TT-EEEEEEESEE..B.S-T.T.---SST---TT..--S......SEEEEEETT---SHHHHHHHHHHTT--TTEEEEEEEE-T.TS-....E---.....---EEEEEEEEEE--EE..........................................
#=GC seq_cons                        ...........p+slpKcllp.s.t...hpKPp-sSpChlplps.l..t.shs.s.ptsphlpt.p.....h......ppctplhlGpuso.lDphlEhllppMhhsEputssIsht.ttp....p...........lphplpL.ph..h...........................................
//
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