#=GF ID GCP5-Mod21_C
#=GF AC PF20685.1
#=GF DE Gamma-Tubulin ring complex non-core subunit mod21, C-terminal
#=GF AU Chuguransky S;0000-0002-0520-0736
#=GF SE PF14069
#=GF GA 27.40 27.40;
#=GF TC 27.40 27.40;
#=GF NC 27.30 27.30;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Domain
#=GF CL CL0540
#=GF RN [1]
#=GF RM 17021256
#=GF RT Noncore components of the fission yeast gamma-tubulin complex.
#=GF RA Anders A, Lourenco PC, Sawin KE;
#=GF RL Mol Biol Cell. 2006;17:5075-5093.
#=GF RN [2]
#=GF RM 32610137
#=GF RT Promiscuous Binding of Microprotein Mozart1 to gamma-Tubulin
#=GF RT Complex Mediates Specific Subcellular Targeting to Control
#=GF RT Microtubule Array Formation.
#=GF RA Huang TL, Wang HJ, Chang YC, Wang SW, Hsia KC;
#=GF RL Cell Rep. 2020;31:107836.
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC GCP5-Mod21 is a non-core subunit of the larger gamma-tubulin
#=GF CC ring complex that effects microtubule nucleation from both
#=GF CC centrosomal and non-centrosomal sites. This subunit, unlike GCP2
#=GF CC and and GCP3 and others, is not essential for viability in the
#=GF CC fission yeast, and may not be expressed in very high
#=GF CC concentrations. Fission yeast can form a large gamma-Tubulin
#=GF CC complex C similar to that found in higher eukaryotes and this
#=GF CC complex is important for maintaining normal levels of
#=GF CC microtubule nucleation in vivo [1,2]. This entry represents the
#=GF CC C-terminal domain of Mod21 from fission yeast. This domain may
#=GF CC consist of an alpha-helical bundle.
#=GF SQ 41
#=GS A0A3E2GXV8_SCYLI/230-301 AC A0A3E2GXV8.1
#=GS A0A183LDF3_9TREM/103-174 AC A0A183LDF3.1
#=GS A0A1X7SR33_AMPQE/31-99 AC A0A1X7SR33.1
#=GS A0A078ASJ6_STYLE/369-440 AC A0A078ASJ6.1
#=GS H0EJ21_GLAL7/211-280 AC H0EJ21.1
#=GS A0A212C294_CEREH/117-183 AC A0A212C294.1
#=GS A0A8B9FUS1_9PSIT/221-288 AC A0A8B9FUS1.1
#=GS T1FTI0_HELRO/210-278 AC T1FTI0.1
#=GS Q0CAP4_ASPTN/1-55 AC Q0CAP4.1
#=GS A0A4Q4T4Z7_9PEZI/228-291 AC A0A4Q4T4Z7.1
#=GS A0A075B032_ROZAC/245-311 AC A0A075B032.1
#=GS A0A0G2GNH3_9EURO/211-278 AC A0A0G2GNH3.1
#=GS A0A0D1YTV8_9EURO/214-280 AC A0A0D1YTV8.1
#=GS A0A183K306_9TREM/103-174 AC A0A183K306.1
#=GS A0A5K4FBK1_SCHMA/103-174 AC A0A5K4FBK1.1
#=GS B6K1F8_SCHJY/226-294 AC B6K1F8.1
#=GS A0A1L9Q1Z7_ASPVE/223-289 AC A0A1L9Q1Z7.1
#=GS A0A8B8Y4B5_BALMU/264-331 AC A0A8B8Y4B5.1
#=GS A0A267EKB5_9PLAT/307-381 AC A0A267EKB5.1
#=GS A0A7E6CR21_9CHIR/265-332 AC A0A7E6CR21.1
#=GS A0A7J8CMK2_ROUAE/264-331 AC A0A7J8CMK2.1
#=GS A0A162RM83_MUCCL/264-330 AC A0A162RM83.1
#=GS A0A1Y3N0Y4_PIRSE/289-356 AC A0A1Y3N0Y4.1
#=GS A0A2R6RMY8_ACTCC/29-96 AC A0A2R6RMY8.1
#=GS A0A4Z2DVB0_SCHJA/102-174 AC A0A4Z2DVB0.1
#=GS A0A183NZ41_9TREM/103-174 AC A0A183NZ41.1
#=GS S9X6D6_SCHCR/232-301 AC S9X6D6.1
#=GS A0A4Q4ZR07_9PEZI/228-291 AC A0A4Q4ZR07.1
#=GS A0A8B8XWB0_BALMU/117-184 AC A0A8B8XWB0.1
#=GS A0A4Q4UDE1_9PEZI/229-292 AC A0A4Q4UDE1.1
#=GS A0A2B4SGE3_STYPI/472-539 AC A0A2B4SGE3.1
#=GS A0A6P6DKE2_OCTDE/265-332 AC A0A6P6DKE2.1
#=GS A0A430QQ38_SCHBO/103-174 AC A0A430QQ38.1
#=GS A0A4Q4Y7Y8_9PEZI/228-291 AC A0A4Q4Y7Y8.1
#=GS MOD21_SCHPO/224-292 AC Q9UT52.2
#=GS A0A395IN48_9HELO/228-293 AC A0A395IN48.1
#=GS A0A1X7T4Z9_AMPQE/31-99 AC A0A1X7T4Z9.1
#=GS A0A452RJA8_URSAM/201-268 AC A0A452RJA8.1
#=GS A0A7J7RTK8_PIPKU/263-330 AC A0A7J7RTK8.1
#=GS A0A7J7RSW4_MYOMY/280-347 AC A0A7J7RSW4.1
#=GS A0A4Y2X9H7_ARAVE/38-106 AC A0A4Y2X9H7.1
A0A3E2GXV8_SCYLI/230-301 ....HITELDAIRDIIFMLFGL.P.S.S.L.F..eI..RT..GDV.TE...VI.P.S.KLC...................YIQ..HAS...TDALDAFLRIFADKGSKIMALRLW-akr..........
A0A183LDF3_9TREM/103-174 ...d-LTEYQLIREIIWVLLGA.R.R.S.F.V...M..QLceNQV.VD...IC.C.K.--Ph................fvSVS..HLS...YNALDSLLRKFVDWNNHILFIR---lvv..........
A0A1X7SR33_AMPQE/31-99 ....QLTEIQAVRESLWVLLGV.RrS.C.V.Y..fI..NE..GGV.VT...VR.N.G.I--...................TLS..HLS...LKSLAKILEFFAKLATKLNRFRRV-v............
A0A078ASJ6_STYLE/369-440 ...a-VTERQLVMDVVLMLQQL.E.S.P.T.F...M..KT..KKK.QD...SR.C.T.FQIrn...............tfQLI..HVT...PKMMESFLAEFIEMGNIINE-----tqwy.........
H0EJ21_GLAL7/211-280 ...p-ITELQAIREVLFMLSGY.P.T.S.L.F...E..TP.sNQS.AQ...IL.P.S.KSY...................VLK..HAS...PDAFYQQISAFAEQGSAIRSLRLW-v............
A0A212C294_CEREH/117-183 ...f-VTETQVIRETLWLLSGV.K.KlF.I.F...-..-Q..LID.GK...VT.V.R.NNI...................IVT..HLT...HSCLQSVLEQIAAYGQKTKL-----ikfc.........
A0A8B9FUS1_9PSIT/221-288 ...l-VTETQVIRETLWLLSGV.K.KlF.I.F...Q..LN..DGK.VA...VR.N.D.I--...................TVT..HLT...HNCLRSVLEQIAAYGQVVFRLQ---kfi..........
T1FTI0_HELRO/210-278 ...l-LSEYQVIRETLWMLSGN.S.Q.Q.L.F...-..-V..FKW.NG...CR.F.K.RNSd.................vIIA..HLA...EKSLHKILNDLSTYGSMIVHLRAY-c............
Q0CAP4_ASPTN/1-55 ....-------------MLQGL.P.T.S.V.F...W..HL.dDGT.IV...VD.R.R.Y--...................ALR..HLS...NEALSSLLRSLSATGAQIDVLRRF-v............
A0A4Q4T4Z7_9PEZI/228-291 ...p-VSELQVVREVFFMLRGL.D.N.T.L.F...-..--..--N.EQ...SV.P.S.MKY...................NLD..HAS...WEVYHDLLGSLGKARRRLAILRRFA.............
A0A075B032_ROZAC/245-311 ...l-LSEYEIVREVLFMLSGL.P.C.A.I.F...P..KE..DNQ.YK...VC.P.E.V--...................VLS..HLS...PKGLMSICEGFVEIANEIYNLK---aia..........
A0A0G2GNH3_9EURO/211-278 ....EITELQAIREGIFMLLGL.P.A.S.L.F...W..RV..DGF.IE...ID.K.R.Y--...................KIS..RLG...YTSSQGALRFLGLLGMQVDHVR---lfvq.........
A0A0D1YTV8_9EURO/214-280 ....AITEKQVIREVLFMMNGL.Q.T.S.I.F...-..-R..LSD.RG...IR.L.D.QNY...................QIA..HLR...AQTSRTILSNAALLGSEVAWIRRWL.............
A0A183K306_9TREM/103-174 ...d-LTEYQLIREIIWVLLGA.R.G.S.F.V...M..QL..CEN.QM...VD.I.C.CKPh................lvSVS..HLS...YNALDSLLGKFVDWNNHILFIR---lvi..........
A0A5K4FBK1_SCHMA/103-174 ...n-LTEYQLIREIIWVLLGA.R.G.C.F.A...M..QLckNQI.VD...IC.CkS.HLT...................SVS..HLS...YDALDSLLRKFVDWNNHILFIR---lvv..........
B6K1F8_SCHJY/226-294 ....QLSQQSMLYEIIYMLMGY.Q.G.H.I.F...-..--..-TC.VE...GV.F.R.PAPfd...............yfQIQ..GLS...TSMQEHILSNFCNWGRELHILNRVA.............
A0A1L9Q1Z7_ASPVE/223-289 ....TITELQMVREVIFMLQGL.P.T.S.L.L...W..RL..DGS.VE...VD.R.R.Y--...................TLA..HLS...QEVLSSILRSIGDCGAKIDILRQFA.............
A0A8B8Y4B5_BALMU/264-331 ...f-VTETQVIRETLWLLSGV.K.KlF.I.F...-..-Q..LID.GK...VT.V.R.NNI...................IVT..HLT...HSCLRSVLEQIAAYGQVVFRL----qefi.........
A0A267EKB5_9PLAT/307-381 ...e-VTQYQAVRETIWMLSGS.R.D.S.M.L...Y..TW..DST.AN...TP.S.V.TVSg................rgCMP..HLT...DGAFDRLLADFANLGTSVARLRL--laerl........
A0A7E6CR21_9CHIR/265-332 ...f-VTETQVIRETLWLLSGV.K.K.L.F.I...F..QL.iDGK.VT...VR.N.D.I--...................TVT..HLT...HSCLRSVLEQMAAYGQVVFRL----qefi.........
A0A7J8CMK2_ROUAE/264-331 ...c-VTETQVIRETLWLLSGV.K.KlF.I.F...-..-Q..LID.GK...VT.V.R.NNI...................TVT..HLT...HSCLRSVLEQVAAYGQVVHRLQE--fi...........
A0A162RM83_MUCCL/264-330 ....TISEANIIREVLSLLRGY.R.S.V.V.Y...-..--..-VY.QE...GQ.F.V.LNQq.................yILQ..HLS...QNALGHLLQEFCQYGNMIAELRQLC.............
A0A1Y3N0Y4_PIRSE/289-356 ...y-VNEVDIVREILFMLMGF.D.T.A.F.F...-..KY..NKN.NC...VD.V.N.KNL...................SLK..HLT...SSCINQLIEYFTDKGSKIKDLR---ift..........
A0A2R6RMY8_ACTCC/29-96 .rtn---EVDLVRGVLHILQGL.S.S.S.L.F...Y..WD..NVR.QD...FH.A.K.SGI...................YVT..HLS...QTSLHVILNQFTYAATC--------lklvevv......
A0A4Z2DVB0_SCHJA/102-174 ...n-LSEYQLIREIIWVLLGA.R.R.C.F.V...L..QLskNQV.VD...ICcK.S.YLV...................SVN..HLT...YNALDSLLHIFADWNDHILFIR---vvvq.........
A0A183NZ41_9TREM/103-174 ...d-LTEYQLIREIIWVLLGA.R.G.S.F.V...M..QL..CEN.QM...VD.I.C.CKPh................lvSVS..HLS...YNALDSLLGKFVDWNNHILFIR---lvv..........
S9X6D6_SCHCR/232-301 ....DVSERWFVKDVIYMLLGL.P.S.F.F.F...H..TH.dTGT.VE...VR.H.Q.MLP...................KVK..MLT...HKLMYSILDVFANYGSCLNNYRNLL.............
A0A4Q4ZR07_9PEZI/228-291 ...p-VSELQVVREVFFMLRGL.D.N.T.L.F...-..--..-NE.Q-...SV.P.S.TKY...................NLD..HAS...WEVYHILLGSLGEARRQLAILRRFA.............
A0A8B8XWB0_BALMU/117-184 ...f-VTETQVIRETLWLLSGV.K.KlF.I.F...-..-Q..LID.GK...VT.V.R.NNI...................IVT..HLT...HSCLRSVLEQIAAYGQVVFRL----qefi.........
A0A4Q4UDE1_9PEZI/229-292 ...p-VSELQAVREVFFMLRGL.D.S.T.L.F...-..--..-NE.QS...A-.P.C.TKY...................NLD..HAS...WEVYHNILGALGKARRQLAILRRFA.............
A0A2B4SGE3_STYPI/472-539 ....TLTETQIVRDTLWMLAGA.Q.N.T.F.V...Y..RH..GQY.GR...IT.V.Q.GHI...................QVL..HLT...PESLSSLLSSFALAGEE--------slslqtf......
A0A6P6DKE2_OCTDE/265-332 ...v-VTETQVIRETLWLLSGV.K.K.L.F.M...-..FQ..LVD.GK...VT.V.R.NNI...................VVT..HLT...QSCLRSALEQIAAYGQVVFRL----qefi.........
A0A430QQ38_SCHBO/103-174 ...d-LTEYQLIREIIWVLLGA.R.G.S.F.V...M..QL..CEN.QM...VD.I.C.CKPh................lvSVS..HLS...YNALDSLLEKFVDWNNHILFIR---lvv..........
A0A4Q4Y7Y8_9PEZI/228-291 ...p-VSELLVVREVLFMLRGL.D.N.T.L.F...-..--..-NE.RS...V-.P.S.TKH...................NLN..HAS...WEVYHSLLRTLGEAGRQLAILRRFA.............
MOD21_SCHPO/224-292 ....RISERSIIRDSIYMLIGY.P.S.F.F.F...L..KN..GSK.IE...TR.L.S.LLP...................KLH..HMS...EEILRSIMTELADYGSNLEFFRQKL.............
A0A395IN48_9HELO/228-293 ...p-ITELQAVREILFMFNGT.L.S.S.L.F..eS..DS..NDV.RI...VR.P.S.KSY...................SLK..HLT...TEGYDMLMETFATQGSA--------srfv.........
A0A1X7T4Z9_AMPQE/31-99 ....QLTEIQAVRESLWVLLGV.RrS.C.V.Y..yI..SE..GGV.VT...VR.N.G.I--...................TLS..HLS...LKSLARILETFAELATKLNRFRRV-v............
A0A452RJA8_URSAM/201-268 ...f-VTETQVIRETLWLLSGV.K.K.L.F.I...F..QL.iDGK.VT...VR.N.S.I--...................IVT..HLT...HSCLRSVLEQIAAYGQVVFRL----qefi.........
A0A7J7RTK8_PIPKU/263-330 ...f-VTETQVIRETLWLLSGV.K.KlF.I.F...-..-Q..LID.GK...IT.V.R.NNI...................IVT..HLT...HSCLRSVLEQIAAYGQVVFQL----qefi.........
A0A7J7RSW4_MYOMY/280-347 ...f-VTETQVIRETLWLLSGV.K.KlF.I.F...-..QL.iDGK.VN...VR.N.-.-NV...................IVT..HLT...HSCLRSVLEQIAAYGQVVFRL----qefi.........
A0A4Y2X9H7_ARAVE/38-106 ...v-LSEQDFVYDVLDLLLGI.P.S.N.T.F...L..YD..DKK.KN...FQ.M.K.PFT...................RLA..RMS...SESTLQFCENFIECGTTFYKLKT--fc...........
#=GC seq_cons .....lTEhQllREslahLpGl.c.s.s.l.F..........stp.tp...lp.s.p.h.....................pls..HLo...hpsLcolLcphushGpplhhl+................
//
