#=GF ID   HCV_NS4b
#=GF AC   PF01001.23
#=GF DE   Hepatitis C virus non-structural protein NS4b
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Pfam-B_315 (release 3.0)
#=GF GA   27.00 27.00;
#=GF TC   248.80 248.80;
#=GF NC   23.50 22.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   9261364
#=GF RT   The hepatitis C virus NS4A protein: interactions with the NS4B
#=GF RT   and NS5A proteins. 
#=GF RA   Lin C, Wu JW, Hsiao K, Su MS; 
#=GF RL   J Virol 1997;71:6465-6471.
#=GF RN   [2]
#=GF RM   9224925
#=GF RT   The nonstructural proteins of the hepatitis C virus: structure
#=GF RT   and functions. 
#=GF RA   Neddermann P, Tomei L, Steinkuhler C, Gallinari P, Tramontano A,
#=GF RA   De Francesco R; 
#=GF RL   Biol Chem 1997;378:469-476.
#=GF DR   INTERPRO; IPR001490;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   No precise function has been assigned to NS4b.  However, it is
#=GF CC   known that NS4b interacts with NS4a and NS3 to form a large
#=GF CC   replicase complex to direct the viral RNA replication [1].
#=GF SQ   2
#=GS O41892_PEGIA/1702-1891  AC O41892.1
#=GS POLG_HCV77/1728-1921    AC P27958.3
O41892_PEGIA/1702-1891             k-AWTAGVLVPPAPALADNAPGLLATLDTMFTQTWEAIFTNGRSLLVGXTAAYGAKRNPPLGVAASFLLGMSAGRAVHVRLAAALLLGVGGTMLGQASTGLAMAGAYFAGGSITSSWLS-IIITLLGGWEGAVNAASLTFDLLSGKAE-AKDAWCIISCLASPGASVAGVALGVLLWSVKK..GVGHDWVNRLLT
POLG_HCV77/1728-1921               .FKQKALGLLQTASRHAEVITPAVQTNWQKLEVFWAKHMWNFISGIQYLAGLSTLPGNPAIASLMAFTAAVTSPLTTGQTLLFNILGGWVAAQLAAPGAATAFVGAGLAGAALDSVGLGKVLVDILAGYGAGVAGALVAFKIMSGEVPSTEDLVNLLPAILSPGALAVGVVFASILRRRVGpgEGAVQWMNRLIA
#=GC seq_cons                      ..t.pAhsLl.sAsthA-shsshltT..phhp.hWtthhhNhhShl.h.suh.sh.tNPslushhuFhhuhoushsst.pLhhslLhGhsus.LutsusuhAhsGAhhAGuulsSshLu.lllslLuGatuuVsuA.lsFclhSGcs..scDhhsllsslhSPGA.ssGVshuslLhphht..tsuhpWhNRLls
//