GenomeNet

Database: Pfam
Entry: HEM4
LinkDB: HEM4
Original site: HEM4 
#=GF ID   HEM4
#=GF AC   PF02602.14
#=GF DE   Uroporphyrinogen-III synthase HemD
#=GF AU   Bashton M, Bateman A
#=GF SE   COG1587
#=GF GA   27.50 27.50;
#=GF TC   27.80 27.60;
#=GF NC   27.40 27.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Uroporphyrinogen_III_synthase
#=GF RN   [1]
#=GF RM   8829650
#=GF RT   Molecular basis of congenital erythropoietic porphyria:
#=GF RT   mutations in the human uroporphyrinogen III synthase gene. 
#=GF RA   Xu W, Astrin KH, Desnick RJ; 
#=GF RL   Hum Mutat 1996;7:187-192.
#=GF RN   [2]
#=GF RM   7597845
#=GF RT   Isolation of the gene HEM4 encoding uroporphyrinogen III
#=GF RT   synthase in Saccharomyces cerevisiae. 
#=GF RA   Amillet JM, Labbe-Bois R; 
#=GF RL   Yeast 1995;11:419-424.
#=GF DR   INTERPRO; IPR003754;
#=GF DR   SCOP; 1jr2; fa;
#=GF CC   This family consists of uroporphyrinogen-III synthase HemD
#=GF CC   EC:4.2.1.75 also known as Hydroxymethylbilane hydrolyase
#=GF CC   (cyclizing) from eukaryotes, bacteria and archaea.  This enzyme
#=GF CC   catalyses the reaction: Hydroxymethylbilane <=>
#=GF CC   uroporphyrinogen-III + H(2)O.  Some members of this family are
#=GF CC   multi-functional proteins possessing other enzyme activities
#=GF CC   related to porphyrin biosynthesis, such as Swiss:Q59294 with
#=GF CC   Pfam:PF00590, however the aligned region corresponds with the
#=GF CC   uroporphyrinogen-III synthase EC:4.2.1.75 activity only.
#=GF CC   Uroporphyrinogen-III synthase is the fourth enzyme in the heme
#=GF CC   pathway [2]. Mutant forms of the Uroporphyrinogen-III synthase
#=GF CC   gene cause congenital erythropoietic porphyria in humans a
#=GF CC   recessive inborn error of metabolism also known as Gunther
#=GF CC   disease [1].
#=GF SQ   4806
#=GS A0A0A0LZ08_CUCSA/44-295     AC A0A0A0LZ08.1
#=GS G2PM03_MURRD/18-236         AC G2PM03.1
#=GS S4LZ83_CHLPS/2-147          AC S4LZ83.1
#=GS A0A0M8KCL4_9BACT/20-239     AC A0A0M8KCL4.1
#=GS A0A177LB36_9BACL/20-247     AC A0A177LB36.1
#=GS A0A0V7ZEI7_9CYAN/299-541    AC A0A0V7ZEI7.1
#=GS A0A0Q4RBR9_9BACL/20-262     AC A0A0Q4RBR9.1
#=GS A0A0A2FW58_9PORP/267-498    AC A0A0A2FW58.1
#=GS A0A0E0NQQ7_ORYRU/58-283     AC A0A0E0NQQ7.1
#=GS H8Z7G4_9GAMM/21-245         AC H8Z7G4.1
#=GS H0ZML1_TAEGU/17-254         AC H0ZML1.1
#=GS G0G5V4_AMYMS/21-263         AC G0G5V4.1
#=GS A0A089UBQ3_9ENTR/13-243     AC A0A089UBQ3.1
#=GS A0A0Q4QVR3_9BACL/268-505    AC A0A0Q4QVR3.1
#=GS A0A085JL80_9GAMM/13-243     AC A0A085JL80.1
#=GS A0A066ZR54_HYDMR/16-238     AC A0A066ZR54.1
#=GS U5WAP7_9ACTN/261-493        AC U5WAP7.1
#=GS A9KSC5_CLOPH/267-487        AC A9KSC5.1
#=GS Q12S94_SHEDO/13-234         AC Q12S94.1
#=GS A0A0D0KNX4_9NOCA/263-495    AC A0A0D0KNX4.1
#=GS A0QPK7_MYCS2/23-270         AC A0QPK7.1
#=GS D7EAG3_METEZ/18-225         AC D7EAG3.1
#=GS X0CUA7_FUSOX/48-324         AC X0CUA7.1
#=GS A0A136MSM2_9BACT/282-514    AC A0A136MSM2.1
#=GS R9AQB2_9GAMM/13-230         AC R9AQB2.1
#=GS A0A0R2BGP4_LACCL/362-458    AC A0A0R2BGP4.1
#=GS N1MHY6_9SPHN/14-216         AC N1MHY6.1
#=GS C5DPU3_ZYGRC/15-245         AC C5DPU3.1
#=GS A0A170U573_9ACTN/27-269     AC A0A170U573.1
#=GS A0A091MZU9_CARIC/17-225     AC A0A091MZU9.1
#=GS R5AXI7_9BACT/17-235         AC R5AXI7.1
#=GS A0YM54_LYNSP/258-492        AC A0YM54.1
#=GS A0A061FC01_THECC/70-295     AC A0A061FC01.1
#=GS A0A0Q8DMG0_9ACTN/20-263     AC A0A0Q8DMG0.1
#=GS J9HEH2_9BACL/1-86           AC J9HEH2.1
#=GS Q18ES1_HALWD/25-248         AC Q18ES1.2
#=GS B9T9A1_RICCO/2-69           AC B9T9A1.1
#=GS M1LXX5_9PROT/16-249         AC M1LXX5.1
#=GS E6SNW4_BACT6/18-237         AC E6SNW4.1
#=GS A0A124I393_9ACTN/35-277     AC A0A124I393.1
#=GS L8EKR1_STRRM/54-296         AC L8EKR1.1
#=GS W9RIJ9_9ROSA/2-80           AC W9RIJ9.1
#=GS A0A0B4Y3E4_9PROT/15-233     AC A0A0B4Y3E4.1
#=GS A0A133XY60_9BACT/21-238     AC A0A133XY60.1
#=GS V9HDV9_9NEIS/15-228         AC V9HDV9.1
#=GS A0A0D2ICG8_9EURO/210-384    AC A0A0D2ICG8.1
#=GS A0A086MP13_9RHIZ/13-225     AC A0A086MP13.1
#=GS A0A0M8W541_9NOCA/15-255     AC A0A0M8W541.1
#=GS H0X3N6_OTOGA/17-253         AC H0X3N6.1
#=GS T0NB93_9CLOT/262-452        AC T0NB93.1
#=GS A0A136H0B2_9GAMM/15-230     AC A0A136H0B2.1
#=GS I4YMT2_9RHIZ/14-226         AC I4YMT2.1
#=GS A0A084IN19_9GAMM/47-269     AC A0A084IN19.1
#=GS A0A168QC77_9BACL/19-260     AC A0A168QC77.1
#=GS A0A090ARH8_9ENTR/8-237      AC A0A090ARH8.1
#=GS A0A060QAH0_9PROT/15-215     AC A0A060QAH0.1
#=GS C0ZX32_RHOE4/21-268         AC C0ZX32.1
#=GS A0A0S8K993_9BACE/20-236     AC A0A0S8K993.1
#=GS G2YB84_BOTF4/43-314         AC G2YB84.1
#=GS A0A139STL4_9BACT/33-277     AC A0A139STL4.1
#=GS D1BI83_SANKS/32-274         AC D1BI83.1
#=GS C4IK27_CLOBU/262-480        AC C4IK27.1
#=GS A0A183W1I3_TRIRE/19-231     AC A0A183W1I3.1
#=GS C1CX88_DEIDV/18-259         AC C1CX88.1
#=GS A0A0K9GA22_9BACI/22-253     AC A0A0K9GA22.1
#=GS A0A099VW26_9HELI/14-218     AC A0A099VW26.1
#=GS V4ILZ3_9ACTN/274-506        AC V4ILZ3.1
#=GS A0A017HFB2_9RHOB/19-223     AC A0A017HFB2.1
#=GS A6LGE7_PARD8/20-239         AC A6LGE7.1
#=GS R6Q1K1_9BACT/20-238         AC R6Q1K1.1
#=GS C6J212_9BACL/266-502        AC C6J212.1
#=GS B4VZ31_9CYAN/295-528        AC B4VZ31.1
#=GS A0A0B5RTJ7_9FLAO/22-236     AC A0A0B5RTJ7.1
#=GS F3NF45_9ACTN/40-282         AC F3NF45.1
#=GS D5V1J7_ARCNC/13-203         AC D5V1J7.1
#=GS K6WWJ1_9MICO/297-529        AC K6WWJ1.1
#=GS A0A0X3SNK2_9ACTN/26-268     AC A0A0X3SNK2.1
#=GS D5UWY3_TSUPD/27-274         AC D5UWY3.1
#=GS A0A0B4RAX6_9BACL/23-223     AC A0A0B4RAX6.1
#=GS S3X0V2_9ACTN/13-228         AC S3X0V2.1
#=GS Q5GVD1_XANOR/32-255         AC Q5GVD1.1
#=GS D3DIB5_HYDTT/17-250         AC D3DIB5.1
#=GS Q8RFP6_FUSNN/264-481        AC Q8RFP6.1
#=GS D9R7V9_CLOSW/267-494        AC D9R7V9.1
#=GS A0A165ELA8_EXIGL/19-284     AC A0A165ELA8.1
#=GS A0A0Q4C9C9_9SPHN/15-210     AC A0A0Q4C9C9.1
#=GS V9VXK1_9RHOB/16-222         AC V9VXK1.1
#=GS Q2CJM1_OCEGH/18-223         AC Q2CJM1.1
#=GS A0A0C1Q758_9ACTN/1-140      AC A0A0C1Q758.1
#=GS Q0RS15_FRAAA/343-574        AC Q0RS15.1
#=GS A0A0M2YKP5_9ACTN/31-273     AC A0A0M2YKP5.1
#=GS K7I9J5_CAEJA/19-134         AC K7I9J5.1
#=GS F7QHG9_9BRAD/13-237         AC F7QHG9.1
#=GS R6IC19_9FIRM/268-497        AC R6IC19.1
#=GS A0A0Q8CJB9_9MICO/26-250     AC A0A0Q8CJB9.1
#=GS A0A0J6CWE7_9BACI/20-240     AC A0A0J6CWE7.1
#=GS A0A0B8N954_9NOCA/1-215      AC A0A0B8N954.1
#=GS S2XPN0_9BACL/22-243         AC S2XPN0.1
#=GS V4LI75_EUTSA/93-270         AC V4LI75.1
#=GS A0A080K9C3_9NEIS/20-232     AC A0A080K9C3.1
#=GS A4A9F8_9GAMM/17-246         AC A4A9F8.1
#=GS W4L450_9BACT/30-258         AC W4L450.1
#=GS Q49YA1_STAS1/10-217         AC Q49YA1.1
#=GS A0A099ZME0_TINGU/17-221     AC A0A099ZME0.1
#=GS G7XLY8_ASPKW/33-333         AC G7XLY8.1
#=GS F4C7S2_SPHS2/26-243         AC F4C7S2.1
#=GS D2RGG8_ARCPA/13-220         AC D2RGG8.1
#=GS A0A101ISS5_9EURY/33-154     AC A0A101ISS5.1
#=GS A0A015M0K5_9BACL/267-504    AC A0A015M0K5.1
#=GS A0A0D0D9A6_9HOMO/16-288     AC A0A0D0D9A6.1
#=GS W7J3P1_9PSEU/23-267         AC W7J3P1.1
#=GS H8FTY6_PHAMO/14-231         AC H8FTY6.1
#=GS A0A100YSB2_9FIRM/266-496    AC A0A100YSB2.1
#=GS R5I897_9PORP/18-237         AC R5I897.1
#=GS C6W5B0_DYAFD/30-248         AC C6W5B0.1
#=GS W7KMC5_9CREN/9-210          AC W7KMC5.1
#=GS A0A0Q5L214_9MICO/22-243     AC A0A0Q5L214.1
#=GS A6EES9_9SPHI/314-518        AC A6EES9.1
#=GS D5BBP0_ZUNPS/26-206         AC D5BBP0.1
#=GS A9SKU8_PHYPA/70-293         AC A9SKU8.1
#=GS B6K1J4_SCHJY/15-243         AC B6K1J4.1
#=GS X5A584_9BACL/19-260         AC X5A584.1
#=GS B5YJZ5_THEYD/265-500        AC B5YJZ5.1
#=GS D4DSQ8_NEIEG/15-226         AC D4DSQ8.1
#=GS R6GBC5_9FIRM/264-488        AC R6GBC5.1
#=GS E0TD21_PARBH/13-230         AC E0TD21.1
#=GS A0A0G3UUU0_9ACTN/15-257     AC A0A0G3UUU0.1
#=GS A0A171DD63_9ACTN/258-490    AC A0A171DD63.1
#=GS D4YXR9_SPHJU/14-215         AC D4YXR9.1
#=GS W9B000_9MYCO/23-270         AC W9B000.1
#=GS A0A087N4Q6_9BACI/20-233     AC A0A087N4Q6.1
#=GS H2Q2R3_PANTR/17-253         AC H2Q2R3.1
#=GS A8G847_SERP5/13-243         AC A8G847.1
#=GS A0A0K9JQ55_9BURK/19-273     AC A0A0K9JQ55.1
#=GS Q20YU6_RHOPB/19-258         AC Q20YU6.1
#=GS F0Y9P9_AURAN/53-280         AC F0Y9P9.1
#=GS B4NA74_DROWI/25-246         AC B4NA74.1
#=GS A0A0K2E0V5_PISSA/24-233     AC A0A0K2E0V5.1
#=GS A0A072SD90_9ACTN/299-531    AC A0A072SD90.1
#=GS H6NR34_9BACL/272-509        AC H6NR34.1
#=GS YJJA_BACSU/19-260           AC O34394.1
#=GS B4U866_HYDS0/115-221        AC B4U866.1
#=GS M1MUK2_9CORY/294-527        AC M1MUK2.1
#=GS B8I0Q9_CLOCE/266-492        AC B8I0Q9.1
#=GS W0HSF3_9GAMM/13-243         AC W0HSF3.1
#=GS J6GSX4_9PORP/262-494        AC J6GSX4.1
#=GS B3QWI2_CHLT3/14-241         AC B3QWI2.1
#=GS F0IDU5_9FLAO/14-211         AC F0IDU5.1
#=GS A8LP84_DINSH/20-220         AC A8LP84.1
#=GS A1ZTV5_9BACT/34-252         AC A1ZTV5.1
#=GS Q756B6_ASHGO/18-249         AC Q756B6.2
#=GS Q0FE44_9RHOB/19-218         AC Q0FE44.1
#=GS W8VWB6_9FLAO/1-141          AC W8VWB6.1
#=GS A0A0A1MVN0_9BACI/18-256     AC A0A0A1MVN0.1
#=GS A0A0L6CUS7_9RHOB/28-225     AC A0A0L6CUS7.1
#=GS D9V728_9ACTN/63-306         AC D9V728.1
#=GS Q7M8K3_WOLSU/19-205         AC Q7M8K3.1
#=GS Q59Y07_CANAL/22-260         AC Q59Y07.1
#=GS F6EFT0_HOYSD/27-274         AC F6EFT0.1
#=GS A0A0C3ATW5_9HOMO/1-74       AC A0A0C3ATW5.1
#=GS M2R1S1_CERS8/16-301         AC M2R1S1.1
#=GS J4SGK1_PASMD/13-72          AC J4SGK1.1
#=GS A0A098M8D4_9BACL/266-503    AC A0A098M8D4.1
#=GS V9HH02_9CLOT/262-480        AC V9HH02.1
#=GS A0A022MQF2_9ACTN/300-532    AC A0A022MQF2.1
#=GS I2ERZ8_EMTOG/31-249         AC I2ERZ8.1
#=GS R6YKP5_9BACT/17-237         AC R6YKP5.1
#=GS A6GW25_FLAPJ/19-236         AC A6GW25.1
#=GS A0A177CVH6_9PLEO/26-304     AC A0A177CVH6.1
#=GS F6CIX8_DESK7/267-498        AC F6CIX8.1
#=GS I1EC63_AMPQE/5-129          AC I1EC63.1
#=GS A0A0P7YNJ3_9RHOB/37-245     AC A0A0P7YNJ3.1
#=GS E7M0P4_YEASV/20-266         AC E7M0P4.1
#=GS N4UE25_FUSC1/34-318         AC N4UE25.1
#=GS R6WLW2_9BACT/17-239         AC R6WLW2.1
#=GS A0A0X8G364_9FIRM/267-496    AC A0A0X8G364.1
#=GS W9CM87_9HELO/129-401        AC W9CM87.1
#=GS A0A067GX46_CITSI/63-285     AC A0A067GX46.1
#=GS A0A062TZJ5_9RHOB/16-233     AC A0A062TZJ5.1
#=GS Q2FRP2_METHJ/15-212         AC Q2FRP2.1
#=GS HEM4_METTH/11-242           AC O26268.1
#=GS A6C1N1_9PLAN/270-499        AC A6C1N1.1
#=GS A0A0B7MGT4_9FIRM/44-271     AC A0A0B7MGT4.1
#=GS I0RF57_MYCXE/23-270         AC I0RF57.1
#=GS A0A0C1R9A7_9ACTN/20-236     AC A0A0C1R9A7.1
#=GS A0A090I8C6_9GAMM/15-243     AC A0A090I8C6.1
#=GS R8BT36_TOGMI/11-206         AC R8BT36.1
#=GS A0A125QKK7_9SPHN/14-218     AC A0A125QKK7.1
#=GS S3Y4K0_9ACTN/269-501        AC S3Y4K0.1
#=GS A0A0M8UZ00_9ACTN/300-532    AC A0A0M8UZ00.1
#=GS U3C955_9VIBR/13-239         AC U3C955.1
#=GS H3GT07_PHYRM/30-257         AC H3GT07.1
#=GS A0A0N1KJR4_9GAMM/13-242     AC A0A0N1KJR4.1
#=GS P95217_MYCTU/23-270         AC P95217.1
#=GS Q6LLM8_PHOPR/10-239         AC Q6LLM8.1
#=GS H2ANA3_KAZAF/29-249         AC H2ANA3.1
#=GS Q4K3X4_PSEF5/16-245         AC Q4K3X4.1
#=GS Q6CZG2_PECAS/13-243         AC Q6CZG2.1
#=GS A0A0Q5ZF70_9RHIZ/13-233     AC A0A0Q5ZF70.1
#=GS Q1NNG9_9DELT/1-46           AC Q1NNG9.1
#=GS K0YZL1_9ACTO/17-218         AC K0YZL1.1
#=GS S4XMR6_SORCE/295-534        AC S4XMR6.1
#=GS Q5SKH2_THET8/12-242         AC Q5SKH2.1
#=GS Q5SKH2_THET8/12-242         DR PDB; 1WD7 B; 20-250;
#=GS Q5SKH2_THET8/12-242         DR PDB; 1WD7 A; 20-250;
#=GS Q5SKH2_THET8/12-242         DR PDB; 1WCX A; 20-250;
#=GS Q5SKH2_THET8/12-242         DR PDB; 1WCW A; 20-250;
#=GS A0A0D6TM01_9FLAO/14-211     AC A0A0D6TM01.1
#=GS A0A150LVY1_9BACI/16-245     AC A0A150LVY1.1
#=GS W9XT02_9EURO/244-410        AC W9XT02.1
#=GS A0A024HAR8_PSEKB/16-246     AC A0A024HAR8.1
#=GS A0A0K9X991_9ACTN/281-513    AC A0A0K9X991.1
#=GS A0A022KU02_9MICO/1-208      AC A0A022KU02.1
#=GS A0A0S8FCW7_9GAMM/21-248     AC A0A0S8FCW7.1
#=GS D5DSS3_BACMQ/18-258         AC D5DSS3.1
#=GS E6WHF6_PANSA/13-243         AC E6WHF6.1
#=GS D9QV28_ACEAZ/267-496        AC D9QV28.1
#=GS A0A0T6LY35_9ACTN/274-506    AC A0A0T6LY35.1
#=GS J1FBV8_9HELI/13-201         AC J1FBV8.1
#=GS A0A058Z8A1_9EUKA/12-296     AC A0A058Z8A1.1
#=GS A0A099B8U4_9HELI/28-172     AC A0A099B8U4.1
#=GS S0FHC3_9FIRM/273-502        AC S0FHC3.1
#=GS G7WNE8_METH6/262-484        AC G7WNE8.1
#=GS F0STH7_RUBBR/14-259         AC F0STH7.1
#=GS A5PC65_9SPHN/15-219         AC A5PC65.1
#=GS A0A0Q9TBX8_9ACTN/283-515    AC A0A0Q9TBX8.1
#=GS I0RZ30_MYCXE/293-525        AC I0RZ30.1
#=GS A0A124JXT2_9SPHN/14-217     AC A0A124JXT2.1
#=GS E4PK72_MARAH/25-252         AC E4PK72.1
#=GS F6GGJ8_LACS5/334-520        AC F6GGJ8.1
#=GS U1ZPJ5_9PSED/1-144          AC U1ZPJ5.1
#=GS C8WZS9_DESRD/265-499        AC C8WZS9.1
#=GS C5ABI2_BURGB/202-355        AC C5ABI2.1
#=GS E6TZR4_BACCJ/20-250         AC E6TZR4.1
#=GS A0A0D5YS68_9FLAO/158-355    AC A0A0D5YS68.1
#=GS A0A0Q5LMP2_9BURK/26-277     AC A0A0Q5LMP2.1
#=GS R5UI94_9BACT/19-235         AC R5UI94.1
#=GS W1J863_9GAMM/13-243         AC W1J863.1
#=GS W5WKH9_9PSEU/256-488        AC W5WKH9.1
#=GS A0A101SKP0_9ACTN/301-533    AC A0A101SKP0.1
#=GS V9TUC8_9PROT/16-233         AC V9TUC8.1
#=GS D3SFF7_THISK/29-273         AC D3SFF7.1
#=GS V5C2E5_9GAMM/20-256         AC V5C2E5.1
#=GS G7J5U1_MEDTR/71-294         AC G7J5U1.1
#=GS H5VE31_HELBI/11-217         AC H5VE31.1
#=GS C5WDQ8_9ENTR/13-243         AC C5WDQ8.1
#=GS A0A0C2TBE6_BACBA/19-260     AC A0A0C2TBE6.1
#=GS A0A0K2RES4_9MICC/1-122      AC A0A0K2RES4.1
#=GS A0A170Y356_9ACTN/300-532    AC A0A170Y356.1
#=GS A0A0A0LLB2_CUCSA/69-293     AC A0A0A0LLB2.1
#=GS Q63W72_BURPS/21-259         AC Q63W72.1
#=GS E3E9X8_PAEPS/266-504        AC E3E9X8.1
#=GS F4G3X7_ALIDK/20-266         AC F4G3X7.1
#=GS A0A0R2R1B5_9ACTN/19-238     AC A0A0R2R1B5.1
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#=GS A0A0G4P4T0_PENCA/17-284     AC A0A0G4P4T0.1
#=GS A0A172ZKE4_9BACL/266-503    AC A0A172ZKE4.1
#=GS A0A0W1SJ18_9GAMM/3-242      AC A0A0W1SJ18.1
#=GS A0A0Q5VDG6_9ACTN/30-273     AC A0A0Q5VDG6.1
#=GS M4BT52_HYAAE/20-224         AC M4BT52.1
#=GS A0A094GXD5_9PEZI/30-309     AC A0A094GXD5.1
#=GS K0YE39_9CORY/309-542        AC K0YE39.1
#=GS D7CHT2_STRBB/247-479        AC D7CHT2.1
#=GS A0A0B5DDU6_9ACTN/299-531    AC A0A0B5DDU6.1
#=GS E3FZX9_STIAD/20-245         AC E3FZX9.1
#=GS A0A0R3T188_HYMNN/21-245     AC A0A0R3T188.2
#=GS A0A0K9PFK5_ZOSMR/50-275     AC A0A0K9PFK5.1
#=GS A0A0D0EZL2_9SPHI/282-519    AC A0A0D0EZL2.1
#=GS B5JT00_9GAMM/20-243         AC B5JT00.1
#=GS A0A0Q6Z3Q3_9BRAD/19-258     AC A0A0Q6Z3Q3.1
#=GS G8AEA9_AZOBR/16-239         AC G8AEA9.1
#=GS H5TY11_9ACTN/31-278         AC H5TY11.1
#=GS R0JW51_SETT2/31-299         AC R0JW51.1
#=GS G8TMG4_NIAKG/26-236         AC G8TMG4.1
#=GS S0ESZ5_CHTCT/285-520        AC S0ESZ5.1
#=GS A0A125RDI1_9EURY/16-245     AC A0A125RDI1.1
#=GS A0A0S2I107_9BACT/18-236     AC A0A0S2I107.1
#=GS S5XRF4_PARAH/14-207         AC S5XRF4.1
#=GS A0A0R3JR16_9CLOT/262-479    AC A0A0R3JR16.1
#=GS A0A0C1F242_9FLAO/19-236     AC A0A0C1F242.1
#=GS A0A0M3AV30_9SPHN/15-215     AC A0A0M3AV30.1
#=GS A0A095YXJ0_9FIRM/266-495    AC A0A095YXJ0.1
#=GS A0A094JES9_9GAMM/13-234     AC A0A094JES9.1
#=GS D5C408_NITHN/27-256         AC D5C408.1
#=GS A0A136LV87_9BACT/27-245     AC A0A136LV87.1
#=GS A0A0D1VJA7_ANEMI/387-481    AC A0A0D1VJA7.1
#=GS A0A0R2B7X6_LACCL/35-221     AC A0A0R2B7X6.1
#=GS A0A170Y770_9PORP/17-239     AC A0A170Y770.1
#=GS K1E5R0_9MICO/21-264         AC K1E5R0.1
#=GS A0A0B7HW04_9FLAO/18-236     AC A0A0B7HW04.1
#=GS A0A0N7HBL6_9ARCH/26-287     AC A0A0N7HBL6.1
#=GS A0A098SZS7_9PSED/16-245     AC A0A098SZS7.1
#=GS A0A0X3TLL6_9RHOB/11-218     AC A0A0X3TLL6.1
#=GS A0A0Q9QZZ6_9MICC/25-285     AC A0A0Q9QZZ6.1
#=GS I3ZZT9_ORNRL/24-242         AC I3ZZT9.1
#=GS B1MEZ0_MYCA9/24-271         AC B1MEZ0.1
#=GS A0A0M1J476_9GAMM/23-103     AC A0A0M1J476.1
#=GS L7WD05_NONDD/13-208         AC L7WD05.1
#=GS Q0AH88_NITEC/21-251         AC Q0AH88.1
#=GS A0A0R0BMI0_9GAMM/23-248     AC A0A0R0BMI0.1
#=GS G2FVW4_9FIRM/267-496        AC G2FVW4.1
#=GS C0ZAH2_BREBN/25-255         AC C0ZAH2.1
#=GS Q295X0_DROPS/20-250         AC Q295X0.2
#=GS A0A0F3INY0_9GAMM/20-199     AC A0A0F3INY0.1
#=GS Z5XKR9_9GAMM/13-236         AC Z5XKR9.1
#=GS F4HFE2_GALAU/13-241         AC F4HFE2.1
#=GS R4SHC7_AMYOR/251-483        AC R4SHC7.1
#=GS Q5UY50_HALMA/20-248         AC Q5UY50.1
#=GS A4H3M9_LEIBR/15-275         AC A4H3M9.1
#=GS H1YYI0_9EURY/15-209         AC H1YYI0.1
#=GS A6R6J1_AJECN/162-246        AC A6R6J1.1
#=GS Q9K8G1_BACHD/21-243         AC Q9K8G1.1
#=GS D2UGP9_XANAP/32-254         AC D2UGP9.1
#=GS F9PKL3_9ACTO/40-297         AC F9PKL3.1
#=GS A0A0Q8A2I1_9ACTN/21-264     AC A0A0Q8A2I1.1
#=GS B9SC14_RICCO/28-280         AC B9SC14.1
#=GS R6JVL8_9CLOT/270-509        AC R6JVL8.1
#=GS B4GFK7_DROPE/20-251         AC B4GFK7.1
#=GS I4A0F0_ORNRL/46-210         AC I4A0F0.1
#=GS F9EWD8_9NEIS/37-174         AC F9EWD8.1
#=GS G8RV46_MYCRN/308-540        AC G8RV46.1
#=GS Q6CU72_KLULA/15-254         AC Q6CU72.1
#=GS E3J4N0_FRASU/355-586        AC E3J4N0.1
#=GS A0A078FHB0_BRANA/54-279     AC A0A078FHB0.1
#=GS F9Z4L9_ODOSD/18-237         AC F9Z4L9.1
#=GS A0A0D7ADU4_9AGAR/4-287      AC A0A0D7ADU4.1
#=GS D5UT19_TSUPD/308-540        AC D5UT19.1
#=GS J4KSV4_9GAMM/17-199         AC J4KSV4.1
#=GS R6R8G3_9FIRM/267-494        AC R6R8G3.1
#=GS H3A4J3_LATCH/17-254         AC H3A4J3.1
#=GS E0SKN3_DICD3/13-243         AC E0SKN3.1
#=GS A0A0P7GP48_9EURY/17-234     AC A0A0P7GP48.1
#=GS A0A0B5FW86_9DELT/267-497    AC A0A0B5FW86.1
#=GS A0A0Q9Y312_9BACI/23-253     AC A0A0Q9Y312.1
#=GS A0A0Q5V8K5_9CAUL/15-221     AC A0A0Q5V8K5.1
#=GS A0M6C3_GRAFK/15-206         AC A0M6C3.1
#=GS F8L6H7_SIMNZ/238-432        AC F8L6H7.1
#=GS A0A0M5LV84_9PSEU/251-487    AC A0A0M5LV84.1
#=GS R5JI64_9BACE/18-237         AC R5JI64.1
#=GS D8PF14_9BACT/270-480        AC D8PF14.1
#=GS Q8Y7S0_LISMO/263-481        AC Q8Y7S0.1
#=GS C0W552_9ACTO/10-262         AC C0W552.1
#=GS Q7UN37_RHOBA/22-266         AC Q7UN37.1
#=GS A0A0C5FX15_9ACTN/27-269     AC A0A0C5FX15.1
#=GS A0A150AG05_9BACT/29-247     AC A0A150AG05.1
#=GS H2G0Z7_OCESG/13-240         AC H2G0Z7.1
#=GS A0A0U2WHQ6_9BACL/267-504    AC A0A0U2WHQ6.1
#=GS A0A0L7LFK7_9NEOP/12-237     AC A0A0L7LFK7.1
#=GS K0ILK5_NITGG/20-260         AC K0ILK5.1
#=GS A0A0N0N0L1_9ACTN/30-272     AC A0A0N0N0L1.1
#=GS Q7VJY8_HELHP/22-232         AC Q7VJY8.1
#=GS A0A0S7YV49_9DELT/263-494    AC A0A0S7YV49.1
#=GS D5UEL2_CELFN/20-263         AC D5UEL2.1
#=GS U5QQ49_9CYAN/257-490        AC U5QQ49.1
#=GS A0A0A2MJ51_9FLAO/15-211     AC A0A0A2MJ51.1
#=GS C6BW74_DESAD/265-496        AC C6BW74.1
#=GS A0A0P0DXR1_9MICO/28-250     AC A0A0P0DXR1.1
#=GS A0A0C2ARZ7_9ACTN/284-516    AC A0A0C2ARZ7.1
#=GS A0A094CNL4_9PEZI/30-334     AC A0A094CNL4.1
#=GS K8WM86_9GAMM/13-242         AC K8WM86.1
#=GS A0A077EEN2_9FLAO/19-236     AC A0A077EEN2.1
#=GS Q0K7M6_CUPNH/16-278         AC Q0K7M6.1
#=GS A0A022LS55_9MICO/1-176      AC A0A022LS55.1
#=GS A0A0P4UMZ9_9CYAN/20-254     AC A0A0P4UMZ9.1
#=GS A0A0C3DG00_9HOMO/25-295     AC A0A0C3DG00.1
#=GS I0I3W3_CALAS/29-263         AC I0I3W3.1
#=GS A0A0U3PZQ9_9ACTN/299-531    AC A0A0U3PZQ9.1
#=GS I0I5K9_CALAS/32-264         AC I0I5K9.1
#=GS J5PRG0_9RHOB/13-233         AC J5PRG0.1
#=GS F4KWR3_HALH1/33-217         AC F4KWR3.1
#=GS D4JBU7_9FIRM/566-788        AC D4JBU7.1
#=GS A0A0P7HVR6_9MICC/34-278     AC A0A0P7HVR6.1
#=GS M9RBY2_9RHOB/11-222         AC M9RBY2.1
#=GS F7BID5_XENTR/17-187         AC F7BID5.1
#=GS A6UT45_META3/15-237         AC A6UT45.1
#=GS A0A172RXT1_9ACTN/271-510    AC A0A172RXT1.1
#=GS I0R385_9MICO/12-237         AC I0R385.1
#=GS F4XAU5_9FIRM/264-484        AC F4XAU5.1
#=GS E3RYQ1_PYRTT/24-299         AC E3RYQ1.1
#=GS G1Q7N5_MYOLU/1-169          AC G1Q7N5.1
#=GS K9SE55_9CYAN/274-506        AC K9SE55.1
#=GS E5UI89_NEIMU/15-228         AC E5UI89.1
#=GS V8C9U1_9HELI/20-222         AC V8C9U1.1
#=GS C9R2R2_AGGAD/13-242         AC C9R2R2.1
#=GS A0A089XBX3_STRGA/35-277     AC A0A089XBX3.1
#=GS A0A0D8ZP26_9CYAN/257-487    AC A0A0D8ZP26.1
#=GS A0A0C2JAD8_9ACTN/43-285     AC A0A0C2JAD8.1
#=GS A0A0Q7XJI3_9RHIZ/10-226     AC A0A0Q7XJI3.1
#=GS H8H0U2_DEIGI/18-258         AC H8H0U2.1
#=GS F2LG73_BURGS/19-139         AC F2LG73.1
#=GS A0A0M2NPM1_9FIRM/265-480    AC A0A0M2NPM1.1
#=GS A0A0E4CZM2_9BACL/19-260     AC A0A0E4CZM2.1
#=GS W4VAB0_9FIRM/268-319        AC W4VAB0.1
#=GS A0A074XWM2_AURPU/31-302     AC A0A074XWM2.1
#=GS Q5FPS4_GLUOX/9-209          AC Q5FPS4.1
#=GS C6RFU1_9PROT/7-204          AC C6RFU1.1
#=GS A0A0M2CRM3_9MICC/22-267     AC A0A0M2CRM3.1
#=GS A0A0S9CPB4_9MICC/19-274     AC A0A0S9CPB4.1
#=GS A0A0Q7KPT2_9ACTN/31-274     AC A0A0Q7KPT2.1
#=GS A0A0P1ILP4_9RHOB/22-226     AC A0A0P1ILP4.1
#=GS T1HKN9_RHOPR/21-244         AC T1HKN9.1
#=GS A0A0N0UXR6_9BACT/31-249     AC A0A0N0UXR6.1
#=GS U2K4Y0_9FIRM/266-487        AC U2K4Y0.1
#=GS J4VTB7_9PORP/19-237         AC J4VTB7.1
#=GS A0A0F2S770_9FIRM/267-496    AC A0A0F2S770.1
#=GS A0A090PYX7_9FLAO/2-66       AC A0A090PYX7.1
#=GS D5QCZ0_KOMHA/11-227         AC D5QCZ0.1
#=GS A0A093H124_PICPB/17-254     AC A0A093H124.1
#=GS A0A0N1EKF4_9GAMM/14-237     AC A0A0N1EKF4.1
#=GS A0A101J141_9EURY/14-211     AC A0A101J141.1
#=GS Q7MXI3_PORGI/21-238         AC Q7MXI3.1
#=GS A0A074MEY5_ERYLO/15-218     AC A0A074MEY5.1
#=GS A0A0M1NVJ1_9BACI/263-367    AC A0A0M1NVJ1.1
#=GS D8DTV0_PREBR/7-207          AC D8DTV0.1
#=GS Q30R75_SULDN/104-293        AC Q30R75.1
#=GS V5CTW1_ENTCL/13-243         AC V5CTW1.1
#=GS A0A086Y3R6_9RHOB/29-242     AC A0A086Y3R6.1
#=GS A0A0N0K9S6_9PROT/14-223     AC A0A0N0K9S6.1
#=GS A0A0P7ZAR1_9GAMM/15-242     AC A0A0P7ZAR1.1
#=GS E6K5H5_9BACT/21-238         AC E6K5H5.1
#=GS A0A0C3E6H0_9HOMO/25-301     AC A0A0C3E6H0.1
#=GS R7A6C5_9FIRM/281-378        AC R7A6C5.1
#=GS J9S8I6_9ACTN/299-531        AC J9S8I6.1
#=GS L0L0X3_METHD/19-257         AC L0L0X3.1
#=GS L1MJF2_9BACT/17-229         AC L1MJF2.1
#=GS A0A0D2G2V6_9EURO/45-221     AC A0A0D2G2V6.1
#=GS A0A150J4G2_9EURY/256-455    AC A0A150J4G2.1
#=GS A0A0M9YXA0_9ACTN/27-269     AC A0A0M9YXA0.1
#=GS B2V6G9_SULSY/15-250         AC B2V6G9.1
#=GS A0A0D8ID89_9CLOT/267-496    AC A0A0D8ID89.1
#=GS J9KHN1_ACYPI/24-247         AC J9KHN1.2
#=GS A0A101G7C0_9FIRM/267-498    AC A0A101G7C0.1
#=GS Q88B90_PSESM/16-245         AC Q88B90.1
#=GS Q88B90_PSESM/16-245         DR PDB; 3RE1 A; 16-245;
#=GS Q88B90_PSESM/16-245         DR PDB; 3RE1 B; 16-245;
#=GS I9C739_9SPHN/13-217         AC I9C739.1
#=GS A0A096APG7_9BURK/16-241     AC A0A096APG7.1
#=GS A0A101SQF2_9ACTN/300-532    AC A0A101SQF2.1
#=GS A0A0K9GIS6_9BACI/18-258     AC A0A0K9GIS6.1
#=GS A0A0M4LLW6_9MICC/27-273     AC A0A0M4LLW6.1
#=GS W0ZA52_9MICO/25-268         AC W0ZA52.1
#=GS A0A0D2BJT9_9EURO/245-410    AC A0A0D2BJT9.1
#=GS A0A0N0I8S3_9BACI/21-245     AC A0A0N0I8S3.1
#=GS E0VBP6_PEDHC/76-306         AC E0VBP6.1
#=GS A0A0S8EYV6_9DELT/268-499    AC A0A0S8EYV6.1
#=GS A0A142XJJ0_9PLAN/271-504    AC A0A142XJJ0.1
#=GS A0A075MI59_9RICK/1-203      AC A0A075MI59.1
#=GS G7YJZ8_CLOSI/19-244         AC G7YJZ8.1
#=GS R4M0W9_9ACTN/261-493        AC R4M0W9.1
#=GS D5CLC2_SIDLE/21-244         AC D5CLC2.1
#=GS A0A125A195_9FLAO/21-236     AC A0A125A195.1
#=GS K0K4U0_SACES/256-488        AC K0K4U0.1
#=GS U3GSV3_9CORY/305-538        AC U3GSV3.1
#=GS A0A099P617_PICKU/619-856    AC A0A099P617.1
#=GS T0DCC8_ALIAG/15-241         AC T0DCC8.1
#=GS A0A0C2M2E6_9CYAN/288-529    AC A0A0C2M2E6.1
#=GS A0A1A6C4U9_9GAMM/27-256     AC A0A1A6C4U9.1
#=GS A0A0W7X2V6_9ACTN/24-266     AC A0A0W7X2V6.1
#=GS A0A166RD84_9ACTN/341-572    AC A0A166RD84.1
#=GS D3PRS8_MEIRD/13-214         AC D3PRS8.1
#=GS A0A0U5H5U4_9EURY/15-235     AC A0A0U5H5U4.1
#=GS A0A089LYF1_9BACL/266-503    AC A0A089LYF1.1
#=GS A0A0P6WG74_9RHIZ/13-233     AC A0A0P6WG74.1
#=GS U5WS85_MYCKA/300-532        AC U5WS85.1
#=GS C9YZC3_STRSW/314-546        AC C9YZC3.1
#=GS A0A0X3WCV3_9ACTN/283-515    AC A0A0X3WCV3.1
#=GS N6Y3G3_9RHOO/8-236          AC N6Y3G3.1
#=GS D0GL81_9FUSO/265-487        AC D0GL81.1
#=GS Q5T3L8_HUMAN/17-138         AC Q5T3L8.1
#=GS A0A126RRF2_9SPHN/14-215     AC A0A126RRF2.1
#=GS U4UPK6_DENPD/21-251         AC U4UPK6.1
#=GS A0A0M2JGT4_9ACTN/36-278     AC A0A0M2JGT4.1
#=GS A0A0A7RZA7_9GAMM/12-239     AC A0A0A7RZA7.1
#=GS W2CMZ8_9PORP/1-176          AC W2CMZ8.1
#=GS A0A0J7YRE5_STRVR/27-269     AC A0A0J7YRE5.1
#=GS F3SBA9_9PROT/1-209          AC F3SBA9.1
#=GS K9PLW2_9CYAN/287-519        AC K9PLW2.1
#=GS A8LDG5_FRASN/340-572        AC A8LDG5.1
#=GS A0A0F7LXB8_9GAMM/24-256     AC A0A0F7LXB8.1
#=GS U5VU57_9ACTN/40-280         AC U5VU57.1
#=GS R6T4S4_9FIRM/262-480        AC R6T4S4.1
#=GS A0A091AXK8_9GAMM/37-259     AC A0A091AXK8.1
#=GS K6XUJ5_9ALTE/14-235         AC K6XUJ5.1
#=GS D4S8F0_9FIRM/269-498        AC D4S8F0.1
#=GS G1UBC3_CANAL/22-260         AC G1UBC3.1
#=GS A0A0S8EH68_9CHLR/268-496    AC A0A0S8EH68.1
#=GS A0A0N1KG21_9BACI/15-121     AC A0A0N1KG21.1
#=GS A0A0S1SD44_9FLAO/13-213     AC A0A0S1SD44.1
#=GS A0A165G6T5_9PEZI/79-231     AC A0A165G6T5.1
#=GS A0A0S3FY83_9FLAO/18-235     AC A0A0S3FY83.1
#=GS S0JF11_9FIRM/558-776        AC S0JF11.1
#=GS A0A067R6A3_ZOONE/23-252     AC A0A067R6A3.1
#=GS A6WXJ3_OCHA4/23-239         AC A6WXJ3.1
#=GS M4R8N0_BIBTR/13-244         AC M4R8N0.1
#=GS A0A014MAN9_9BURK/16-256     AC A0A014MAN9.1
#=GS D6U6V1_9CHLR/26-282         AC D6U6V1.1
#=GS A0A0C1RLT4_9ACTN/22-240     AC A0A0C1RLT4.1
#=GS H2TEH6_TAKRU/17-254         AC H2TEH6.1
#=GS A0A098Y8D4_9ACTN/21-264     AC A0A098Y8D4.1
#=GS A0A0P9H3Z2_9CHLR/1-109      AC A0A0P9H3Z2.1
#=GS A0A021X383_9RHIZ/13-239     AC A0A021X383.1
#=GS A0A162GIV8_9MICO/29-253     AC A0A162GIV8.1
#=GS A0A0Q9S6Y0_9MICO/15-258     AC A0A0Q9S6Y0.1
#=GS V4R8S0_9RHIZ/11-232         AC V4R8S0.1
#=GS F6QDV4_BOVIN/17-253         AC F6QDV4.1
#=GS G3B9T4_CANTC/1-195          AC G3B9T4.1
#=GS I4MMT6_9BURK/22-263         AC I4MMT6.1
#=GS E6WP64_PSEUU/28-250         AC E6WP64.1
#=GS A0A0M1NVJ1_9BACI/383-480    AC A0A0M1NVJ1.1
#=GS A0A0D0LLT9_9NOCA/26-273     AC A0A0D0LLT9.1
#=GS A0A0D1LE27_9MYCO/23-270     AC A0A0D1LE27.1
#=GS E9G2V3_DAPPU/23-189         AC E9G2V3.1
#=GS A6GI22_9DELT/261-503        AC A6GI22.1
#=GS O67647_AQUAE/26-239         AC O67647.1
#=GS K9FCX4_PEND2/1-115          AC K9FCX4.1
#=GS E8RK44_DESPD/277-511        AC E8RK44.1
#=GS E3PXF7_CLOSD/265-490        AC E3PXF7.1
#=GS D5XEC9_THEPJ/267-498        AC D5XEC9.1
#=GS A0JUD0_ARTS2/42-284         AC A0JUD0.1
#=GS A0A0U3H9P4_9MICC/21-266     AC A0A0U3H9P4.1
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#=GS H8KS49_SOLCM/315-521        AC H8KS49.1
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#=GS F6SZ75_HORSE/17-253         AC F6SZ75.1
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#=GS R6HA93_9FIRM/1-113          AC R6HA93.1
#=GS F6D4P7_METPW/22-256         AC F6D4P7.1
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C6J212_9BACL/266-502                   ...........................................................s-ELVRGI.EE..L..G...G.E..P...Y.EF...PVID..IAMp......................eGQE.L.AS...T.DEAL......N.......Q......L........E.....-............-.........QYDWVFFTSVN...GVEYFFSHLE...............................................................RLGK.D.V..R.G..LH..............KA.R.IA..AV.GPAT....QA..A.LRQ.........R...G.................IAAEG..................................LP.G...-...K.F...Q...A...E.GL.......ME...TYGS..................ELKP.gQH............................VLL.................PR.G.D.LA...............RAW.L.P.......AAL.R......................EQ.G.....L.T.VTEAVMYRT.....VPAGE...........................................TDE..E..L.L.K.L..L.EK......GRI......................................H.A.V.T.FTS.SS.T.V....TN.L.....L..A..A..LTGMGva.........................dpvAALQ.GV....D..IA..C.IG.PVT......AKTA....E...D.......A....G.......L.R..V.....S..I.L..A.EEATIDSLIQ.........................................................
B4VZ31_9CYAN/295-528                   ...........................................................s-TFRDLL.EK..E..G...A.T..V...I.EM...PALV..ITP........................PSS.W.DA...L.DQAI......T.......N......L........S.....-............-.........DFDWLILTSSN...GVKYFFERLL...............................................................TLGK.D.S..R.A..LS..............GV.K.IA..VV.GKKT....AA..S.LKE.........R...G.................LHPDF..................................IP.P...-...D.F...V...A...D.SL.......VE...HFPE..................PLAE..QT............................ILF.................PR.V.E.TG..............gREV.L.V.......KDL.T......................AQ.G.....A.T.IVEVAAYQS.....TCPGE...........................................IAP..P..A.A.A.A..L.QN......HTV......................................N.I.I.T.FAS.SK.T.V....KN.F.....R..K..L..LDKNSnh..........................plSLLE.NV....C..IA..S.IG.PET......SKTC....Q...Q.......L....L.......G.R..V.....D..V.E..A.QQYTLEGLTQ.........................................................
A0A0B5RTJ7_9FLAO/22-236                ....................................................eleqkfkv-------.--..-..-...-.K..I...D.FR...PFIH..VEG........................-VP.A.KE...V.RHQK......I.......D......L........N.....-............-.........NYTAIILTSKN...SVDHFFRVAE...............................................................--EM.R.Y..K.V..PE..............TL.K.YF..CQ.SEAV....AY..Y.LQK.........YvvyR.................KRKIY..................................VG.Q...-...-.K...D...F...A.EL.......AP...LIK-..................KYKD..ET............................FLL.................PA.S.D.QL...............NHD.V.P.......TTL.N......................DL.K.....V.N.WTPGTFYRT.....-VM--...........................................--S..D..L.S.D.L..A.-D......VKY......................................D.V.L.A.FFS.PT.G.I....KS.L.....F..K..N..FPDF-..............................-SQD.NT....R..IA..V.FG.TTT......QKEA....L...D.......N....N.......L.R..V.....D..I.M..A.PAPGTPSMT-m........................................................
F3NF45_9ACTN/40-282                    ...........................................................e-ELGALL.ER..R..G...A.V..V...Q.HA...PALR..IVP........................LSD.D.SE...L.LAAT......K.......E......L........L.....H............Q.........TPDVVVATTAI...GFRGWIEAADg............................................................wgLGEE.L.L..T.R..LR..............DV.E.LL..AR.GPKV....KG..A.VRA.........A...G.................LTERW..................................SP.S...S...E.S...M...A...E.VL.......DR...LLEE..................GVEG..RR............................IAV................qLH.G.-.EP...............LPG.F.V.......EAL.R......................ES.G.....A.E.VVGVPVYRW.....MPPEDv.........................................gPLD..R..L.L.D.T..T.VA......GGI......................................D.A.L.T.FTS.AP.A.A....AS.L.....F..S..R..ARERGmld.......................dllaVLGH.EV....L..AA..C.VG.PVT......AVPL....Q...A.......R....G.......V.P..T.....-..V.Q..P.ERFRLGPLVQ.........................................................
D5V1J7_ARCNC/13-203                    ......................................................egvenl-------.--..-..-...-.-..-...-.--...PVFD..IEY........................---.-.--...L.DIRI......N.......-......L........Q.....-............-.........EYDSLIFTSKN...AIYALDKAS-...............................................................----.-.-..L.P..WT..............NL.D.SY..AI.AKKT....SD..I.LKK.........H...N.................SNVVF..................................TG.V...-...S.S...H...G...D.NF.......AY...ELIP..................LLKN..KK............................VLY.................VK.G.E.KS...............VSK.L.F.......NIL.K......................DN.K.....I.N.VEELIVYKT.....ICN--...........................................KKD..L..K.V.P.A..L.--......--N......................................S.I.I.I.FTS.PS.C.V....KC.F.....F..D..K..IV---..............................-WDE.SY....K..AI..V.IG.NTT......AKYM....P...K.......-....-.......-.-..-.....-..-.-..-.----------nikyktsptqsieaci.........................................
K6WWJ1_9MICO/297-529                   .........................................................gdt---LERL.AR..Y..G...A.H..G...E.VV...PTIS..VEP........................PRT.P.QQ...M.QKAI......K.......G......L........V.....T............G.........RYEWVGFTSVN...AVRAVKEKLA...............................................................EIGL.D.V..R.A..FA..............GL.K.IA..AV.GGVT....AQ..A.LRE.........W...G.................LEPDL..................................VP.D...G...E.E...S...A...R.GL.......LE...VWPPy...............ddVL--..DPi.........................ngVFL.................PR.A.D.IA...............TDT.L.V.......AGL.Q......................EI.G.....W.A.VDDVTAYRT.....VRAAP...........................................PPA..P..T.R.E.A..I.KT......GAF......................................D.A.V.V.FTS.SS.T.V....RN.L.....V..G..I..AGK--..............................-PHA.ST....V..VA..C.IG.PAT......AKTA....Q...E.......H....G.......L.N..V.....A..V.I..A.ESASSDALI-d........................................................
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S3X0V2_9ACTN/13-228                    .........................................................tde----KAL.AT..V..G...I.D..S...I.TV...PLLQ..MVQ........................PAD.T.GD...A.TGLA......V.......R......M........S.....-............-.........RGGVLFLTSPR...TWQAWANLVPd.............................................................lEAHL.A.R..G.I..AA..............GL.E.IW..TV.GART....AA..S.LPQ.........V...A.................AKVTH..................................TG.S...-...G.V...S...A...A.DL.......LE...EID-..................NLPP..GV............................ALL.................PQ.S.A.LA...............RPT.L.A.......MGL.G......................LR.G.....W.Q.VHTAAVYSM.....-VPVP...........................................DP-..-..-.-.A.L..P.DP......GEV......................................D.G.V.L.LRS.PS.A.V....RA.L.....T..E..H..WA---..............................--AG.TV....Q..VF..A.VG.PST......TAEA....E...H.......L....G.......W.Q..P.....V..T.I..T.H---------tapdhv...................................................
Q5GVD1_XANOR/32-255                    ..........................................................ap--LRRAV.AR..H..G...G.R..V...L.AL...SPWR..LQT........................-ND.A.AQ...A.RDAL......R.......Q......A........L.....-............-.........AAPIAVFTSPA...AVQAAHRLAP...............................................................----.-.L..Q.R..PA..............QA.H.WV..SV.GDGT....AR..A.LQA.........C...G.................IDTVV..................................RP.T...-...R.M...D...S...E.GL.......LA...-LPL..................LQAP.lQA............................VGL.................IT.A.P.GG...............RGM.L.A.......PTL.E......................QR.G.....A.R.IVRADVYQR.....-IPLR...........................................LRA..S..A.I.Q.A..L.SH.....aLPR......................................S.V.L.A.LSS.AE.A.L....TL.V.....L..Q..Q..LPSAL.............................iEKWQ.QR....P..VV..A.SS.DRM......LDAA....H...A.......A....G.......F.I..H.....R..M.R..A.EGPLPKQL--aa.......................................................
D3DIB5_HYDTT/17-250                    ........................................................eeai----ESI.VK..L..G...G.K..P...Y.VE...DVVR..IVA........................-LP.D.EV...I.KENI......K.......N......A........V.....F............E.........APEIFYFTTGE...GTDVLLKKSR...............................................................-EIG.L.Y..E.P..LL..............KG.K.VF..AR.GYKV....RA..R.LIN.........Y...G.................FKN--..................................FQ.S...-...V.E...S...T...R.AF.......MN...MLKD.................iEILN..TK............................ILV................qMY.G.E.-E...............MHE.L.E.......EFL.N......................NK.G.....A.K.MLKLWLYRY.....ETDTE...........................................RLD..A..F.I.I.K..L.LE......GFY......................................H.A.V.L.FTS.AY.Q.V....DY.I.....F..K..R..AKEKNlgk.......................nlssSLNN.KV....F..TV..A.VG.RKT......AGKL....F...E.......N....G.......V.L..R.....V..Y.Y..P.EKER------ltyal....................................................
Q8RFP6_FUSNN/264-481                   ...........................................................v-EMSENI.SK..R..G...G.I..P...V.EL...PFIE..IEN........................---.-.--...L.KIDL......K.......D......L........E.....-............-.........KYKAILFNSPN...GVKAFFENIK...............................................................----.D.I..R.C..LA..............NI.K.IG..AV.GVKT....KE..I.LEK.........Y...K.................IVPDF..................................VP.N...-...E.Y...L...V...D.KL.......AE...EVVK..................YTNE.nDN............................ILI.................VT.S.D.ISp.............cDTD.K.Y.......NSL.-......................-Y.K.....R.N.YEKVVAYNT.....KKLKV...........................................DRE..K..V.L.E.T..L.--......KDI......................................D.I.I.T.FLS.SS.T.V....EA.F.....Y..E..N..LDGDF..............................FILG.DK....K..IA..S.IG.PMT......SETI....K...K.......L....G.......M.K..V.....D..Y.E..A.EKYTADGLL-d........................................................
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A0A165ELA8_EXIGL/19-284                .........................................................dpy---HVEF.NR..L..G...F.R..P...V.FV...PILD..TVF........................-TS.Q.SE...L.QRII......A.......A......G........P.....-............R.........NISGITVTSGR...AADAWRDAAEmv..........................................................aqsERQP.E.G..A.A..WS..............SV.P.FY..AV.GETT....SR..T.LRA.........L...-.................-SDHLpqhlcp......................dvdlilGA.S...E...A.G...T...S...E.AL.......AH...YIVKeh..............hrYENG..GA............................VLE.................LV.G.D.KN...............KDN.L.R.......TIL.A......................EA.G.....I.S.SERLQVYGT.....GPSPS...........................................FAN..D..L.E.R.A..V.VDi...ppDGV......................................T.W.I.A.LFA.PS.A.T....EF.A.....I..P..H..LKNFFqlpttn.................dgahveqAKNR.PA....L..LA..S.IG.PTT......AAFL....R..eT.......L....S.......L.Y..V.....A..V.V..A.PKPDALQ---las......................................................
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V9VXK1_9RHOB/16-222                    ...................................................fvaglpqga-------.-R..A..G...L.Q..V...I.YA...PLMQ..IRP........................---.-.--...I.QAMV......-.......S......L........D.....-............-.........GVKGVIFTSAN...GVEA---ASR...............................................................--ET.A.V..-.-..--..............RL.P.AF..CV.GERT....AV..A.AVN.........A...G.................WQVLS..................................L-.-...-...G.Q...C...A...D.EL.......VG...RLLQ..................KPPK..AP............................LLH.................LR.G.A.HA...............RGG.I.A.......QRL.T......................DG.G.....I.P.CSAQIVYDQ.....-VLLP...........................................LSE..E..A.Q.A.V..L.SA......QMD......................................V.I.V.P.LFS.PR.T.A....CH.F.....A..S..L..CR---..............................-DAA.YL....H..LI..A.LS.GDV......AEPL....K...S.......L....N.......C.K..V.....L..R.V..S.KEPSAGAMA-e........................................................
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A0A0C1Q758_9ACTN/1-140                 .........................................................thq-------.--..-..-...-.-..-...-.-F...PLLD..IAP........................TPN.L.DD...L.RAAL......G.......D......P........S.....-............-.........RYALVVFVSPN...AVQQAFAAMP...............................................................---E.G.F..R.W..PQ..............EV.P.VA..VV.GPAS....AQ..A.LAT.........H...Gvapp.........aysvI---Kpd..............................thAD.D...A...R.Q...D...S...E.AL.......YA...RLDV.................pSLSG..RE............................VLI.................VR.G.N.GG...............REW.L.A.......DQL.R......................EA.G.....A.S.VRTVEA---.....-----...........................................---..-..-.-.-.-..-.--......---......................................-.-.-.-.---.--.-.-....--.-.....-..-..-..-----..............................----.--....-..--..-.--.---......----....-...-.......-....-.......-.-..-.....-..-.-..-.----------.........................................................
Q0RS15_FRAAA/343-574                   ...........................................................i--LSDLL.RS..H..G...A.S..P...L.EV...PTIA..VEP........................PRT.A.AP...M.ERAI......T.......G......L........V.....S............G.........RYQWVAFTSVN...AVRAVQEKVE...............................................................ERSL.D.A..R.A..FA..............GV.K.VA..AI.GEAT....AE..A.LRA.........F...G.................IRPDL..................................VP.T...G...Q.Q...S...S...E.GL.......LE...DWPEy...............deSLDL.lDR............................VLL.................PR.A.D.IA...............TET.L.V.......AGL.K......................DR.G.....W.Q.VDDVTAYRT.....VRAAP...........................................PPA..P..I.R.E.A..L.KG......GRV......................................D.A.V.V.FTS.SS.T.V....RN.L.....V..G..I..AGK--..............................-PHE.TT....V..IA..V.IG.PAT......AATA....Q...E.......L....G.......L.R..V.....D..V.Q..A.PEASIPALV-g........................................................
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