GenomeNet

Database: Pfam
Entry: Herpes_UL4
LinkDB: Herpes_UL4
Original site: Herpes_UL4 
#=GF ID   Herpes_UL4
#=GF AC   PF03277.13
#=GF DE   Herpesvirus UL4 family
#=GF AU   Mifsud W;0000-0002-9805-6461
#=GF SE   Pfam-B_4461 (release 6.5)
#=GF GA   25.00 25.00;
#=GF TC   72.20 72.00;
#=GF NC   20.60 20.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   1323700
#=GF RT   Identification and transcriptional analyses of the UL3 and UL4
#=GF RT   genes of equine herpesvirus 1, homologs of the ICP27 and
#=GF RT   glycoprotein K genes of herpes simplex virus. 
#=GF RA   Zhao Y, Holden VR, Harty RN, O'Callaghan DJ; 
#=GF RL   J Virol 1992;66:5363-5372.
#=GF DR   INTERPRO; IPR004958;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF SQ   27
#=GS E2IUG6_SHV1/7-192        AC E2IUG6.1
#=GS Q9E1W4_CHV9D/8-176       AC Q9E1W4.1
#=GS Q9DPT0_MEHV1/3-230       AC Q9DPT0.1
#=GS A0A0K1R192_9ALPH/4-202   AC A0A0K1R192.1
#=GS NP04_VZVD/56-243         AC P09304.1
#=GS J9QVC1_9ALPH/5-176       AC J9QVC1.1
#=GS Q2QBH3_CHV16/5-192       AC Q2QBH3.1
#=GS Q98105_ILTV/1-177        AC Q98105.1
#=GS UL4_GAHVM/3-235          AC Q77MS6.1
#=GS NP04_HHV2H/5-189         AC P28280.1
#=GS Q7T5E9_CHV1/5-193        AC Q7T5E9.1
#=GS NP04_HHV11/5-187         AC P10188.1
#=GS NP04_PSHV1/1-173         AC Q6UDG8.1
#=GS A0A172DSU9_9ALPH/10-197  AC A0A172DSU9.1
#=GS Q6QCS2_HHV3/56-243       AC Q6QCS2.1
#=GS A0A1R3TFP8_9ALPH/5-203   AC A0A1R3TFP8.1
#=GS A0A0U2UCZ9_9ALPH/11-183  AC A0A0U2UCZ9.1
#=GS A0A288CFW2_EHV4/8-190    AC A0A288CFW2.1
#=GS E6Y394_9ALPH/6-189       AC E6Y394.1
#=GS A7KPZ4_9ALPH/3-235       AC A7KPZ4.1
#=GS A0A0A7D9J7_9ALPH/8-202   AC A0A0A7D9J7.1
#=GS D1FXX8_FHV1/12-202       AC D1FXX8.1
#=GS G3G912_9ALPH/2-142       AC G3G912.1
#=GS A0A060PY78_9ALPH/5-183   AC A0A060PY78.1
#=GS A0A068EVU6_9ALPH/6-217   AC A0A068EVU6.1
#=GS A0A077B621_9ALPH/13-199  AC A0A077B621.1
#=GS A0A1P7U200_9ALPH/4-236   AC A0A1P7U200.1
E2IUG6_SHV1/7-192                   ls--LVAYTLRNARGPTTWKLYDTEHIVSTFDSGVRYVATAGRLRQDPLDGGSVVLQDTPGGVVVVVNCPADFCAYRFVGRTQGHVLR....QWEDTGMCVYPFDAWTGSTH..TESVRSASA........GTAIVLWCDD.SLYITATVCD...............................................ADPPADspTAR.............-VDETP....G-SLLEDA.....HEELLAGDSE..-AR...VAADLLTEVLDQVQL-g..................................................
Q9E1W4_CHV9D/8-176                  .l-TSINYRLCDIENKLDVRIPKCNQALYAYNSGVRSVVIKEKTRCDSLNVGTFILQHTPNVTVLTLDGMTDFASYTFFTRK--KSYT...qTQLQTNTLVVPFENWTVQDL..YLRACNNNK........GLLSVTLGYDlSLSISIIIYE...............................................S-----..---.............------....--------.....----------..---...----------------vytkltsntspvqlpqeprlrqdigvylypndv..................
Q9DPT0_MEHV1/3-230                  ..STFIAYTLENARMSPICNTPPYEQIICSCETGTRSIAVGRMTRCDHIPPSNFIIQRGPVGTLIVVDSGSIIYSYLLRVEEYTAEHHsaslSSLPEALCVIPFATCTVMGT..DAYVYNNSG........GILTILGMGN.SIYVTITIYGqsgilakpcdnfqms................qqmgprrtddeivqknD-----..GSQnmddvetitlepeYPGCRT....-------TftiagHTNNIPGTAE..VSD...AREDLLAEAIREARL-y..................................................
A0A0K1R192_9ALPH/4-202              .i-TSVTYILYCPNHLQRTGLYDFEQCTGIFNGGARIVMVGSVPYHHQLPAGQLLIQRTCTYTTVVINSSSDFCFYKMD-KDIGTKFI....--YNYHAYVDQFATCVIIDRhnDSFVK--GS........GVSNIVFTDT.GVTITVSYYEpsqlsi...................................rppqskSPPT--..---.............------....--------.....----------..---...----------------diieaallaadvkiepvsedqstpprrlkrvchrspdpnakrlrtntddsl
NP04_VZVD/56-243                    ..TTFILYRLHGVRRVLHWTLPDHEQTLYAFTGGSRSMAVKTDARCDTMSGGMIVLQHTHTVTLLTIDCSTDFSSYAFTHRD----FH...lQDKPHATFAMPF--------..MSWVGSDPTsqlysnvgGVLSVITEDDlSMCISIVIYGl............................................rvNRPDDQ..---.............---TTP....TPTPHQYTsqrrqPETNCPSSPQpaFFT...SDDDVLSLILRDA---an.................................................
J9QVC1_9ALPH/5-176                  ..TTTIAYSLRGAQTTFPRAPAEVEQLLCTFGSGSRSVISGGHMRHDPLTCGTVLIQQTPLGLLVVVDSKADFCTYRFNGRGDPPRLD....HSRAANTHVYPFNSWTSTTN..RESAHSIRA........GVFTGLWGSD.STYITITIYG...............................................HASE-H..ASD.............--DHAP....-------A.....P-----RPEE..GSA...PPTDLLVEVLREIQLS...................................................
Q2QBH3_CHV16/5-192                  pa--TIAYSLHGTATSSACVLPDAEQVVCAFESGTRAIASRGCLRHDALSRGAVVVRQTPVGLLVMVDCRAEFCAYRFVGRSERQRLE....RWWDTNLCAYPF--------..DSWVSSTRGesvrsptaGIVTVVWGDD.SIYITVTVYG...............................................SPPEGE..AETp...........aRPPSPP....GESCGTPS.....PPAVSPASAE..-TG...AAADLLVEVMKEIQLS...................................................
Q98105_ILTV/1-177                   ..MIFISYVMVGVQGLGHGSATEYEQVVYSCDGGMRFICIGNKMYRHQLPPGKVIVIHNPVATMIAVDCEEEFCAYCLERNG----SH....RGPSGETLAFQFSACWFLGR..GGTRERWSS........GNITMMNFLG.VAHLTVTIY-...............................................ETPEDL..ASS.............-AHTTP....TCSQSSPEsl.ecPEESV-----..---...----------------prdlvefaarhaglle...................................
UL4_GAHVM/3-235                     ..STFIAYTLENIKASPAWTMPPYEQIICSCEAGTRSIAVGKLSRCDHIPSSNFIIQRGPVGTLIVVDSGTDICSYLLRADESGSEYHttslSSLPESLCVIPFTTCTVMGT..DAYVYNNSG........GVLTIMWMGS.SIYMTITIYGrhdtfaktvdnlhlvq...............ncsrqfyptvvaeprkDDPQQNseAAQvlsks..vpgfieYVGANP....TDTLHEHT.....P----PILDK..FPH..iSGEDILIEALREADLR...................................................
NP04_HHV2H/5-189                    ..QTTIAYSLHHPRASLTSALPDAAQVVHVFESGTRAVLTRGRARQDRLPRGGVVIQHTPIGLLVIIDCRAEFCAYRFIGRASTQRLE....RWWDAHMYAYPF--------..DSWVSSSHGesvrsataGILTVVWTPD.TIYITATIYG...............................................TAPE--..AAR.............GCDNAP....LDVRPTTP.....PAPVSPTAGE..FPA...NTTDLLVEVLREIQIS...................................................
Q7T5E9_CHV1/5-193                   pa--TIAYSLHGTATSSACVLPDAEQVVCAFDGGTRAIASRGCLRQDTLSRGAVVVRQTPVGLLVMVDCRTDFCAYRFVGRSGRQRLE....RWWDTNLCAYPF--------..DSWVSSTRGesvrsptaGIVTVVWGED.SIYITVTVYG...............................................SPPGGE..AEAp..........lpDPSSPP....LDAPGTPS.....PPAVSPASAE..-AG...AAADLLVEVMKEIQLS...................................................
NP04_HHV11/5-187                    ..QTTIAYSLCHARASLTSALPDAAQVVHVFEYGTRAIMVRGRERQDRLPRGGVVIQHTPIGLLVIIDCRAEFCAYRFIGRDSNQKLE....RGWDAHMYAYPF--------..DSWVSSSRGesarsataGILTVVWTAD.TIYITATIYG...............................................SPPEETpgAAH.............GVGAAP....------PP.....PTTACPGTAE..FLQ...PTADLLVEVLREIQLS...................................................
NP04_PSHV1/1-173                    ..MIFISYVMVGVQGLGRGASHEYEQTVYSCDGGMRFICVGNKMYRHPLPPGKVVVIHNPVGTMITVDCEEEFCAYCLERS----GPH....KCPSGETLAFQFSACRFLGR..EGTGERWSS........GNITMMNFLG.VAHLTVTVY-...............................................ETPEVV..ASH.............---GVP....LLSELRAAss.asPAASSPASDR..D--...--------EQT-----raqis..............................................
A0A172DSU9_9ALPH/10-197             .a-TFITYSLHGIKKSPMWVVPNYEQVLCSCLWGSRAIAVGTSLRCDNIQSGNLLIQHGPSVTFLILDCGQEFCSYAFTRLGMARPPL....TTSPESVFMVPFSKWSGVGR..DRCIQSFSG........GIMTLMWDLNeSLHITITIY-...............................................-RPEIV..---.............------....--------.....----------..---...----------------ipiepnmdheketqdkesniqpneqsvsdacdfletilkesnihiqen...
Q6QCS2_HHV3/56-243                  ..TTFILYRLHGVRRVLHWTLPDHEQTLYAFTGGSRSMAVKTDARCDTMSGGMIVLQHTHTVTLLTIDCSTDFSSYAFTHRD----FH...lQDKPHATFAMPF--------..MSWVGSDPTsqlysnvgGVLSVITEDDlSMCISIVIYGl............................................rvNRPDDQ..---.............---TTP....TPTPHQYTsqrrqPETNCPSSPQpaFFT...SDDDVLSLILRDA---an.................................................
A0A1R3TFP8_9ALPH/5-203              .a-TFITYTLRGVRSSQPWAVPDYEQIVCSCDGGTRSVTVGSLSRCDILPPGNFILQKGPAGTLLVLDCEPEFCSYLLR--DCGVHYGq..lSSIPWSLGVFPFSSCTVVGR..DRCVDSSNA.......cGVLTVTWLRE.SVYVTLTVYGsrdisrdeh.............................glvndgaecDGP---..---.............------....--------.....----------..---...----------------naesstlcccggedsisgndavevsdgmndllaeaireaaln.........
A0A0U2UCZ9_9ALPH/11-183             ..TTLIAYSLYEIKMAPLWALPHCEQVVCECAAGDRSVSVGGGLACDALPAGTLVLQHGPAATLVAVDCGSEYCSYAFTHAS-GVRNS...lSLREGSVFVVPF--------..DEWAATDRArrlcsrarGLLAVCLGARrDIHVTITVYGqst.........................................apaT-----..---.............------....--------.....----------..---...----------------apppgdvleailqeseirdcdarpsgsrpc.....................
A0A288CFW2_EHV4/8-190               .v-TFITYALYGIKTSPAWTLPNFEQVISSCGWGYRLIAVGSESRCDVMPKGSFVIQHGASITALVLDCGVEFCSYAFTHADSTRVPL....TTEDGSVLVVPFCGWVCVGR..DRCLRSLSG........GVLTISWDVSqTAYISVAVY-...............................................-RPSTV..QCH.............ALTCTN....VET-----.....----------..---...----------------tgssnaaitdgsdsepsvfanqeadntqdqd....................
E6Y394_9ALPH/6-189                  .a-TFITYTLGGTGASHTWTVPEYEQVICSCDGGSRSVLVGNKTRCDKLPPCNVIIQRGPLGTLFVVDIGYAIYSYMLRCDL-KQQVGt..lSASPGSLYVVPFTSCTVVGV..DSYIRSDSS........GVLTIAWSHN.TVHITITVYG...............................................LSEESQ..RMA.............SVSAIS....TVGQDY--.....-ENLQDIANQ..-EQ...SEEDLLSAAIKEAN--ig.................................................
A7KPZ4_9ALPH/3-235                  ..STFIAYTLENIKASPAWTMPPYGQIICSCEAGTRSIAVGKLSRCDHIPSSNFIIQRGPVGTLIVVDSGTDICSYLLRADESGSEYHttslSSLPESLCVIPFTTCTVMGT..DAYVYNNSG........GVLTIMWMGS.SIYMTITIYGrhdtfaktvdnlhlvq...............ncsrqfyptvvaeprkDDPQQNseAAQvlsks..vpgfieYVGANP....TDTLHEHT.....P----PILDK..FPH..iSGEDILIEALREADLR...................................................
A0A0A7D9J7_9ALPH/8-202              .v-TFITYALYGIKTSPAWTLPNFEQVICSCDWGYRLIAVGAESKCDVTPQGSFVIQHGASITALVLDCGVEFCSYAFTHAENTRVPL....TTEDGSVLVVPFCGWVCVGR..DRCLRSMSG........GVLTISWDTSqTAYISVAVY-...............................................RPPTLQ..-CH.............ALDCTR....AETT----.....----------..---...----------------vcstaaitdasesdplyadqegdqtqdqdgghdfletilmes.........
D1FXX8_FHV1/12-202                  .a-TLITYSLIGVKPSPVWILPSYEQVLCSCEGGTRSIAVGSSSRYDHLQPGNMVIQHGPSVTIILVDCGSEFCAYSFTRLGAVRAPL....TTSAGSVFMMPFIGWSGVGM..DRCIQSNSG........GVVIITWGLNnTVHISITIYRld...........................................spTTPTSL..AVP.............TRDMNGhisdMEDLLTHT.....P----PSRVE..-EA...ETYDFLEAILKESD--lq.................................................
G3G912_9ALPH/2-142                  ta--LVAYSFYEIKLPGGWAQSGCGQTVCEYERGVRVMATDGCTRCDALAPGRVTIQHGPVLTVLAVDGEPERCSYVFA------RTW....PAAPEGALVMPFSTWSCAER..SRRLRGPAG........GLLATLVVER.ALHVTITAY-...............................................-RPDV-..---.............------....--------.....----------..---...----------------lrdalrear..........................................
A0A060PY78_9ALPH/5-183              .p-TTIAYSFYGVQTSPAQTLPDTEQFVARFSSGTRTIISGSRERRDSLAGGAVVLQHTPIGFVAIIDCRTDFCTYRFIGPINQPQLN....FWEKAQLCAYPF--------..RAWVSSTRGesalssaaGLVTVVWGTN.TIFLTATLY-...............................................-TPTPF..AST.............-----P....---SVSEP.....P-SSCPSRQT..SLEesgPAADLLVEVMKEIQLS...................................................
A0A068EVU6_9ALPH/6-217              .a-TFITYTFVGAKTSPTWTVPNYEQIICSCDGGTRSVAVGGMSRCDYLPATNVILQRGPAGTLLILDGGVEFCSYLLRSEDATSARSsgylSSAPGSICVVPFSSCTVIGL..DTYVCNNSS........GVLTVTWLRQ.AAYITLTVYGsgheyrisep..........................gsvsqsscssvASQKDS..AAE.............SCEGRA....VPTPENRV.....PDD-------..---...----------------avaeardgasaprepddvldeiiqwn.........................
A0A077B621_9ALPH/13-199             .v-TFITYALYGIKTSPAWTLPNFEQVLCGCEWGYRLIAVGGDSRCDVLPRGSFVVQHGAAMTAMVFDCGPEFCSYAFTHAG-DSRVP...lTAEGGSVLVVPFSGWVAVGR..DRCLRSSSG........GVATVSWDTNyTAYITIAVY-...............................................-RPSNL..---.............--PSVP....GSSGEE--.....PEPACPALAA..CPK...E---------------leqasvgrapeteahdfletilm............................
A0A1P7U200_9ALPH/4-236              ..STFIAYTLENVTAQPAWTMPPYEQMVCSCAGGTRSIAVGKMTRCDHIPSSNFIIQRGPVGTLIIVDSGADICSYLLRVGECGAEYHaaplSFLPESLCVIPFATCTVTGP..DAYLYSSSG........GILTVMWMGT.SLYITITIYGkpgsltqtanamrvghessarlycqaiadpnkdahrqscdpirslpeNAPE--..ISK.............CIEAHE....IGAVHGYG.....P----SKVDA..FST..gYEEDLLTEAIREADI-q..................................................
#=GC seq_cons                       ...ThIsYoLhsl+sosshslPsaEQllsuh-uGoRuluVGspsRpDtLssGslllQ+sPsuTllllDCts-FCoYtFptps.stphp....pshssuhhshPFsshshhsh..DphlpSssu........GllTlhWsss.olaITlTlYt...............................................ssPp......t................s.s....h.s...................t...........................................................................
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