#=GF ID   Imm57
#=GF AC   PF15596.11
#=GF DE   Immunity protein 57
#=GF PI   Imm34;
#=GF AU   Zhang D;0000-0001-8535-7620
#=GF AU   de Souza RF;0000-0002-5284-4630
#=GF AU   Anantharaman V;0000-0001-8395-0009
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   [1]
#=GF GA   25.00 25.00;
#=GF TC   26.40 61.50;
#=GF NC   23.70 22.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 81514348 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   22731697
#=GF RT   Polymorphic toxin systems: comprehensive characterization of
#=GF RT   trafficking modes, processing, mechanisms of action, immunity
#=GF RT   and ecology using comparative genomics.
#=GF RA   Zhang D, de Souza RF, Anantharaman V, Iyer LM, Aravind L;
#=GF RL   Biol Direct. 2012;7:18.
#=GF DR   INTERPRO; IPR028955;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   A predicted immunity protein with a mostly alpha-helical fold
#=GF CC   and conserved aspartate and cysteine residues and an SE motif.
#=GF CC   Proteins containing this domain are present in bacterial
#=GF CC   polymorphic toxin systems as an immediate gene neighbour of the
#=GF CC   toxin gene, usually containing a domain of the LD-peptidase or
#=GF CC   Tox-Caspase families [1].
#=GF SQ   6
#=GS L0M577_ENTBF/14-112      AC L0M577.1
#=GS YIBV_ECOLI/1-99          AC A5A625.1
#=GS A0A345P6Y7_9GAMM/35-128  AC A0A345P6Y7.1
#=GS A0A140N6L0_ECOBD/1-99    AC A0A140N6L0.1
#=GS YIBV_ECO57/1-99          AC Q8X2T9.1
#=GS A0A4Q1JXB2_9GAMM/35-134  AC A0A4Q1JXB2.1
L0M577_ENTBF/14-112                 tpf-----VLQAEISEHQKRTLEFAEHSLVQGKGV-ESDLGLAVIGEGNGPLSLQFLAELVRWRrgMDAGNGESFTCYLLSKGKAILPYLERLDPLTLRKQCVA-e
YIBV_ECOLI/1-99                     ...MADKAILWALISASTKEGRKACSLSYFACKAA-EAELGLAYMAANDNKEFLTSLSNIMRYK..IDAGLSESYTCYLLSKGKIIRPYLKNLNPLQLAADCIET.
A0A345P6Y7_9GAMM/35-128             ...MAESAVLLSIMIPTNEEGR------LYLDNTASAGELGLALIAAKNSKASLNSLAKLLRYR..LDGSLAEDYHCFIPKKGKRVIKYLKQINPTKLETQCLGE.
A0A140N6L0_ECOBD/1-99               ...MADKAILWALISASTKEGRKACSLSYFACKAA-ETELGLAYMAANDNKEFLTSLSNIMRYK..IDAGLSESYTCYLLSKGKIIRPYLKNLNPLQLAADCIET.
YIBV_ECO57/1-99                     ...MADKAILWALISASTKEGRKACSLSYFACKAA-EAELGLAYMAANDNKEFLTSLSNIMRYK..IDAGLSESYTCYLLSKGKIIRPYLKNLNPLQLAADCIET.
A0A4Q1JXB2_9GAMM/35-134             ...GAEQSILASLVSHRSSGNEYLCAQNLYACTGVDKAELGLSLIGGSRSMAAPRKLLELARFK..MDAGLSSDFKCYVSFRGNAVINQVASVDANKLAAQCREE.
#=GC seq_cons                       ...MA-pAILhALISsooKEGRchCuhShaACKuA.EuELGLAhhAAscsKthLsSLuplhRYK..lDAGLSESYTCYLLSKGKhIhPYLKsLNPLpLAApClEp.
//