#=GF ID InvE_AD
#=GF AC PF05689.15
#=GF DE Adhesion domain
#=GF PI DUF823;
#=GF AU El-Gebali S;0000-0003-1378-5495
#=GF AU Moxon SJ;0000-0003-4644-1816
#=GF SE Pfam-B_2973 (release 8.0)
#=GF GA 32.00 32.00;
#=GF TC 32.10 32.90;
#=GF NC 31.60 31.00;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP Domain
#=GF CL CL0056
#=GF RN [1]
#=GF RM 28370712
#=GF RT Structure of the Y. pseudotuberculosis adhesin InvasinE.
#=GF RA Sadana P, Monnich M, Unverzagt C, Scrima A;
#=GF RL Protein Sci. 2017;26:1182-1195.
#=GF DR INTERPRO; IPR008541;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This entry represents the Adhesion domain found in InvasinE
#=GF CC (invE). Invasins are members of the inverse autotransporter
#=GF CC (IAT) family also referred to as type Ve secretion system. In
#=GF CC general, they consist of an N-terminal beta-barrel-like domain,
#=GF CC which is responsible for attachment of invasin to the outer
#=GF CC membrane region of bacteria, repetitive Immunoglobulin-like (Ig)
#=GF CC domains, which vary significantly in number among all the
#=GF CC invasins, and the C-terminal domain/adhesion domain (AD), which
#=GF CC provides invasins with the specificity to bind to its host
#=GF CC target molecules. InvE-AD adopts a C-type lectin-like domain
#=GF CC (CTLD)fold with unique modifications. The core structure of the
#=GF CC adhesion domain (AD) is made up of a globular alpha/beta fold
#=GF CC and can be divided into three sub-sections. The first is a
#=GF CC lasso-shaped loop structure termed the "adaptor ring" since it
#=GF CC forms a ring-shaped platform that connects BIg21 Pfam:PF05688
#=GF CC with the two residual sub-sections in the AD. These two residual
#=GF CC subsections are the "C-type lectin-like domain" and the "wedge
#=GF CC module". InvE-CTLD lacks the ability to coordinate Ca2+, and
#=GF CC motifs such as EPN, QPD, and WND that are responsible for the
#=GF CC specificity of carbohydrate recognition are also absent, giving
#=GF CC rise to the notion that the InvE-CTLD is not a carbohydrate
#=GF CC binding domain [1].
#=GF SQ 63
#=GS A0A2I0FS34_9GAMM/1793-1918 AC A0A2I0FS34.1
#=GS A0A4Z0KTC6_SALET/14-93 AC A0A4Z0KTC6.1
#=GS A0A3S4E2Y8_SALBN/98-229 AC A0A3S4E2Y8.1
#=GS A0A447M0N7_SALBN/91-217 AC A0A447M0N7.1
#=GS D3VIN8_XENNA/873-1012 AC D3VIN8.1
#=GS A0A085HKG3_9GAMM/2874-3007 AC A0A085HKG3.1
#=GS A0A085HKG2_9GAMM/612-741 AC A0A085HKG2.1
#=GS D3UXD2_XENBS/1764-1910 AC D3UXD2.1
#=GS Q8ZN56_SALTY/1147-1283 AC Q8ZN56.1
#=GS W1ISV3_9GAMM/858-996 AC W1ISV3.1
#=GS A0A085HKG3_9GAMM/875-1007 AC A0A085HKG3.1
#=GS A0A4Z0KA17_SALET/60-200 AC A0A4Z0KA17.1
#=GS D3UYZ9_XENBS/859-994 AC D3UYZ9.1
#=GS Q8ZN55_SALTY/597-722 AC Q8ZN55.1
#=GS Q8ZN55_SALTY/860-991 AC Q8ZN55.1
#=GS Q8ZN56_SALTY/1421-1576 AC Q8ZN56.1
#=GS A0A085HKG3_9GAMM/1427-1582 AC A0A085HKG3.1
#=GS Q8ZN55_SALTY/330-460 AC Q8ZN55.1
#=GS Q8ZN56_SALTY/601-728 AC Q8ZN56.1
#=GS A0A656YH42_SALNE/1-112 AC A0A656YH42.1
#=GS Q8ZN56_SALTY/2011-2147 AC Q8ZN56.1
#=GS A0A845SI55_9GAMM/887-1011 AC A0A845SI55.1
#=GS A0A3S4E2Y8_SALBN/662-802 AC A0A3S4E2Y8.1
#=GS D3UXC7_XENBS/1536-1676 AC D3UXC7.1
#=GS A0A085HKG3_9GAMM/608-735 AC A0A085HKG3.1
#=GS D3V5I5_XENBS/1737-1878 AC D3V5I5.1
#=GS A0A4Z0L7R2_SALET/1-134 AC A0A4Z0L7R2.1
#=GS Q8ZN56_SALTY/2299-2434 AC Q8ZN56.1
#=GS A0A2V1H879_9GAMM/1054-1183 AC A0A2V1H879.1
#=GS W1IWM1_9GAMM/858-996 AC W1IWM1.1
#=GS A0A085HKG3_9GAMM/2017-2153 AC A0A085HKG3.1
#=GS A0A4Z0L7R2_SALET/273-302 AC A0A4Z0L7R2.1
#=GS Q8ZN56_SALTY/1723-1865 AC Q8ZN56.1
#=GS W1IZ47_9GAMM/488-631 AC W1IZ47.1
#=GS Q8ZN55_SALTY/1728-1863 AC Q8ZN55.1
#=GS A0A447M0N3_SALBN/37-174 AC A0A447M0N3.1
#=GS A0A068QMP7_9GAMM/898-1030 AC A0A068QMP7.1
#=GS A0A3S4E2Y8_SALBN/377-520 AC A0A3S4E2Y8.1
#=GS Q8ZN56_SALTY/326-459 AC Q8ZN56.1
#=GS A0A085HKG3_9GAMM/341-467 AC A0A085HKG3.1
#=GS A0A085HKG2_9GAMM/329-468 AC A0A085HKG2.1
#=GS W1J0I8_9GAMM/1814-1947 AC W1J0I8.1
#=GS A0A6H2FNX4_9ENTR/175-306 AC A0A6H2FNX4.1
#=GS A0A2T3MV03_9GAMM/153-269 AC A0A2T3MV03.1
#=GS A0A656YFX4_SALNE/1-116 AC A0A656YFX4.1
#=GS A0A447M0N3_SALBN/320-453 AC A0A447M0N3.1
#=GS Q8ZN55_SALTY/1431-1568 AC Q8ZN55.1
#=GS A0A085HKG3_9GAMM/1728-1870 AC A0A085HKG3.1
#=GS U3APT4_9VIBR/549-667 AC U3APT4.1
#=GS A0A2D0KTV7_9GAMM/874-1012 AC A0A2D0KTV7.1
#=GS A0A2V1H355_9GAMM/340-477 AC A0A2V1H355.1
#=GS A0A4R1NDL5_9GAMM/1109-1234 AC A0A4R1NDL5.1
#=GS A0A085HKG3_9GAMM/1152-1288 AC A0A085HKG3.1
#=GS A0A2U8I7G0_9GAMM/298-424 AC A0A2U8I7G0.1
#=GS A0A085HKG3_9GAMM/2582-2722 AC A0A085HKG3.1
#=GS Q8ZN56_SALTY/869-1000 AC Q8ZN56.1
#=GS A0A1I0AU25_9GAMM/552-685 AC A0A1I0AU25.1
#=GS W1J0T3_9GAMM/1796-1934 AC W1J0T3.1
#=GS A0A4Z0MG49_SALET/161-296 AC A0A4Z0MG49.1
#=GS Q8ZN55_SALTY/1141-1285 AC Q8ZN55.1
#=GS A0A085HKG3_9GAMM/2302-2439 AC A0A085HKG3.1
#=GS Q482D1_COLP3/884-1013 AC Q482D1.1
#=GS A0A4Z0KVL2_SALET/1-129 AC A0A4Z0KVL2.1
A0A2I0FS34_9GAMM/1793-1918 .............PDVATANMWGYMTETLTV-...GALTFQRPYLSS.EKTG--.....-TSTVTQNNEVWALFTWA..AASALC........-----.SVPNETELV....NLYKAY...PN....SGVLTQHGWPLL..........NVY...RTSTS..Y..GGS..----....YKYVYMTNGLLSYNp.gtGNTNS.....YGVSC-k.......................................
A0A4Z0KTC6_SALET/14-93 .........yeta----------------IPV...DNIEFLRPKLAA.AATA--.....ATRTEDQNNETWARVTHA..DALNNPd.....agGCEVN.HLPQEAPGS....AVSSAI...DG....QDMS--------..........---...-----..-..---..----....--------------....-----.....------pgsg....................................
A0A3S4E2Y8_SALBN/98-229 .............PDVATARMWGHMPETITV-...GDLTFERPKLAD.EVSA--.....-IGLQEEANENWARVIHA..DAAGNTa.....agGCAAN.RLPRADQLA....ALYSAN...SG....GDIHNVKGWPVS..........MEY...WSATF..Q..SAS..S---....WQQLSLANGNEVAG....GSSDS.....DYVTCL........................................
A0A447M0N7_SALBN/91-217 .............PDVDGANMYGHMQGVVDA-...-GNLYKRPLLAV.EASH--.....KTGQQSENNEDWATFNSV..EAANL-........QCGAG.QVPDQLSLD....HLYSEN...SE....NAMETVHGWPTQ.........kLSY...ISGDS..D..GTQ..----....TAHVNLSTGDDGLF....TQAD-.....NYLTC-s.......................................
D3VIN8_XENNA/873-1012 .............PDVDVANFWGHMDEAAVAE...NGIVFTRPKLQA.EVTRMHf...kAMDTHTEAGEVWPKRIHF..GAELYC........KGIHG.TLPTKEELM....GLYNAH...PN....NAMHDIYGWPQQ..........RAY...RSSTP..H..IEK..NSRKn..eHYSVNIDLGVLHIV....GKTTT.....EYTICK........................................
A0A085HKG3_9GAMM/2874-3007 .............PDTDKALYWGHMPDTATA-...NGKTLHRPLLVA.ELPSGA....tSPLHVLMNKETWAMAHTV..DANTWDl.....aaQCGSLsNAPDINVLQ....ALHSTF...--....----SSLGWPTT..........TSY...TYLSR..T..TSS..KY--....YCGYNESSGSSSCYi..dAKTTA.....GFAACL........................................
A0A085HKG2_9GAMM/612-741 .............PDSDKATYWGYMPDTVEI-...NGKTLRRPPIVA.EAQLPP....aWTYDGINGDEFWAYSYYE..REDKLNa.....vaQCGSIdNLPDIDDLT....ALKSIV...--....KTLH----WPDG..........-DY...LTKST..N..DKG..--EY...cTYNNYMNCGSSTQA....SGR--.....GLVAC-v.......................................
D3UXD2_XENBS/1764-1910 .............PDTPLANYWGHMEDYITV-...NGKKYSRPPLHS.EAPLHSe..erDDIPDTINRELWVTPQWR..VAADYC........-NKLG.ELPTSDQLM....DIHNAY...PN....GTLYNSYGWPVNyfdnnnnnigN--...-----..-..---..----....--------------....-----.....------fwfwssnivgegyetknivvdinngdvwrletghyfhiic
Q8ZN56_SALTY/1147-1283 .............PDSDKAKMWGHMPETTTAA...NGEVFKRPLLSA.EIASGV.....THGDNTENNEAWGIVDFE..MANDA-........-CGAG.YVPTLADMQ....SLYDAR...PG....GAMNTQQGWPLD.........gKNY...QDSTAdlS..RST..QNRY....VKSINLRDGGVGSL....LWNEQ.....LYFVCL........................................
W1ISV3_9GAMM/858-996 .............PDSKYANFWGHMAETVTNT...NGTIFDRPLLQA.ELAVMGm...kGMTTYTENGEIWPRRVYK..GAVWYC........KKMHK.KLPTAEDLA....SLYQAH...QQ....NAMHELYGWPQF..........RSY...RSSAP..G..IDE..HGKN...aHFAVNIDDGTVHVI....NDIVT.....DYVIC-t.......................................
A0A085HKG3_9GAMM/875-1007 .............PDSPSAQMWGHMSDVITV-...GSDVFSRPKLAD.EAPA--.....AGVTQKENNETWARVNHD..DASGRVd.....tgGCALN.HLPRLDQLS....ALYSAN...SG....NKINTEHGWPVL..........YGY...WSSTP..A..GTS..T---....WKETSLSTGSDTSA....PSSAT.....DYVSCL........................................
A0A4Z0KA17_SALET/60-200 .............PDTPYASYWGHMPDTVEV-...NGVTLRRPFLKT.EMSKMP.....-PGTWPLNNETWAANYID..YGETSIhattslpyLCGSLeNAATLDDLK....ALKNII...--....GDLH----WPTAa.......paSSY...TYDYA..S..QTM..VGGK....YCSFNETTNTENCT....LSSQG....fAYASC-r.......................................
D3UYZ9_XENBS/859-994 .............PDTPLANFWGHMSESVMGA...NGAVFMRPQLQV.ELKGKM....kGLATFFESGEIWPRRVYK..GAEWYC........GKIHA.NLPTQEDLQ....SLYRAY...SA....NEMHDLHGWPQH..........RSY...RSSTP..A..EGN..KV--....HIAVNIDNGFAHPI....EDNIV....sDYVIC-r.......................................
Q8ZN55_SALTY/597-722 .............PDVDGANMWGHMRGVVDA-...-GNLYKRPLLAV.EASH--.....KDGQFSENNEEWATFNSV..ASATA-........QCGVG.QVPDQSSLA....HLYSEH...AG....GQMESEHGWPTE..........DYF...IAADS..D..ASG..----....TVHVNLENGDSGKF....TDTP-.....NYLTC-s.......................................
Q8ZN55_SALTY/860-991 .............PDTPAAKMWGHMADTITV-...GDWTFERPKLAG.EVSN--.....PLRTQDESNETWARVAHS..DAVGNPd.....agGCAAN.RLPRIDQLE....ALYNAN...SG....GKIHSIQGWPTY..........LNY...WSSTY..Q..SAT..T---....WKLIALTNGSEFAN....SNV-S.....IYASCL........................................
Q8ZN56_SALTY/1421-1576 .............PDTPKANYWGHMAETLTDS...SGVAYRRPLLAS.EFSATPgktltIANGYYDKGETWGMITVD..KAWNGTg......gGCGRD.TLPTVANLQ....TLYGTY...PD....NAMRSRNGWPMTssgn..nnvsRYW...WAGDY..V..ISS..DGTKs..lYAAVNLFNDGNDVK....TTTSTs..myYMQTCL........................................
A0A085HKG3_9GAMM/1427-1582 .............PDTPKANYWGHMADTLTSS...DGLVYKRPLLAS.EFASAPgksfaITNGDYDKGETWGLITVT..NAWNGTn......dGCGRS.YLPTAANLQ....ALYNTY...PD....GAMRTVNGWPVVnkgn..ayvtQFW...WAGDY..A..APS..SESAq.laYMTVNLLSGGDIST....TTSTSa...yYMQSCL........................................
Q8ZN55_SALTY/330-460 .............PDSDKASMYGHMIESATATlngITYTFTRPKLAA.EASG--.....ADKSVVDTNETWALFTWS..GADNHC........----D.ILPDAEQLV....QMRHEH...--....STLETWTGWPVAg........dAEY...WSSTK..N..QLS..GY--....HAAVHMNSASVVRA....ADSDT.....LLVSCV........................................
Q8ZN56_SALTY/601-728 .............PDVAQARMWGHMQGVVEA-...-GNIYKRPLLAD.EAAQ--.....DTGSEFENNEYWATFNSV..TAATN-........QCGTG.QVPGQLLLD....TLYQAH...SG....NAMETTYGWPTQ.........kHSY...IAADT..D..GST..----....TAHVNLATGADSTF....SGTEP.....NYLSCS........................................
A0A656YH42_SALNE/1-112 ..........mdg-------------------...ASYTFYRPKLAA.ETDG--.....EDRTASINNESWAQFNWG..HADAHC........----D.ILPDARQLE....GLKIER...--....GDLSTTLGWPVGlt.....sgdEEY...WSSSQ..G..STA..TD--....HISIDMRSRSLTQM....PDATQ.....S-----lv......................................
Q8ZN56_SALTY/2011-2147 .............PDSDKAKYWGHMPETVTNS...AGVKFRRPLLAA.EMTS--.....NSGTYLVNNETWPLVTAA..NTEKAGa......tGCDAE.YQPLSGDLQ....TLYSDN...PN....GAIGTNYGWPVAg........nKSW...WAADR..A..PNT..GY--....YQFINLNSGGKGTA....SSSTA....tGAQVCL........................................
A0A845SI55_9GAMM/887-1011 .............PDSEFAYYWGHMQDTVDG-...----IKRPALRL.EVDR--.....PSAFYRQNNEQWVVMDNV..GAESW-........-CGTG.KLPNAAALT....GLHARH...--....GSMSSAFGWPD-..........KYY...VTSSY..A..VKG..ADKY....ALMINLANGDTNIG...lTPLEP.....QLVAC-a.......................................
A0A3S4E2Y8_SALBN/662-802 .............PDSDQANMWGHMPETFSAG...NGAEFKRPLLYK.ELPQKSid.sgEVYSSTESNESWYTINYF..DTSDSG........ACSWE.QMATMADYQ....SLYAAH...PG....GAVTTDLGLPVA..........KTW...WAADR..I..LKG..QALY....WQYINLKSGVASSI....SANGN....fYYQLCL........................................
D3UXC7_XENBS/1536-1676 .............PDTPKANYWGHMEDYITL-...NGIKYSRPQLNA.ELNG--.....-ESKLTRNREIWGMAQWI..IVKDYC........-NKLG.ELPTRDQLM....DIHNAY...QN....RTLYDTNGWPINsln...gfglN-I...WSSSL..W..NPN..IDIN....ITVVDIISGKEGS-....-----.....------agnagnhgggdysvic........................
A0A085HKG3_9GAMM/608-735 .............PDTDKARMWGHMQGVVNA-...-GNIYKRPMLAD.EAEH--.....KTGLFRENDEDWATFNSL..DAAVS-........QCGVG.QVPDVSSLE....NLYSAN...AS....NQMEIKYGWPTE.........gYDY...LAADN..D..GSN..----....FHHVDLSNGNESGF....SGGQP.....NYLTCS........................................
D3V5I5_XENBS/1737-1878 .............PDTDLANYWGHMVEELPI-...NAGKFSRPLLSK.EVQKYYp..nlSTGIVQENNEDWSAYNYE..NFKNLC........QAKGK.RAPQIGELQ....ELGGLV..qDK....YQFTPTYGWPTVs........sRSW...YRSDT..D..APN..QGPH...lKSSYALDNFKIGKN....GPSDI.....NMVSC-i.......................................
A0A4Z0L7R2_SALET/1-134 .............---DKAKMWGHMPETVATA...NGEVFKRPLLSA.EVASGI.....THGSNTENNETWGSVNFE..VAKDA-........-CGAG.FVPSLADLQ....SLYDTW...PG....GAMNTQQGWPLD.........gKNY...QDSTA..DlsRTS..ENRY....VKSINLRDGGIGSL....LWDEK.....LYFVCL........................................
Q8ZN56_SALTY/2299-2434 .............PDTDKALFWGNMSDTTSV-...NGKTLHRPWLQA.EMLSGVt..pvFTNGVHANNEYWAMAHTV..DNTKWDi.....akQCGSLsKAPDNNDLL....TLYHSI...--....----SSLGWPTQ..........-GY...PYLSK..S..TSS..GG-M....YCGVDENTKSQNCAi..kPAGSA.....GYATCV........................................
A0A2V1H879_9GAMM/1054-1183 .............PDTDLANMWGYMPNTLQLT..dQSVTFKRPFLQK.EKAT--.....-ADSVQIANEVWARFTLN..EATATC........-----.SLPTKDQLI....ALYNQY...PG....NAMSTNNGWPTA..........TVY...RSSTI..D..SVS..GQ--....HYYVQLRDGASNY-....-----.....------nvtgvggdalaynls.........................
W1IWM1_9GAMM/858-996 .............PDVDVANFWGHMADTITV-...NGMTFTRPLLET.EIVKNGd..hrHETIITEYGEIWPRRMNT..GANWFC........KKETD.TVPTKDELL....SLYQTY...PE....NRIHELFGWPQH..........RSY...RTSTP..A..IND..KGKT...aHYAVNISDGYAHVI....DEDVT.....DYVTCK........................................
A0A085HKG3_9GAMM/2017-2153 .............PDSDKAQMWGHMPETVTNS...AGVKFYRPMLVG.EAPL--.....TSYSYTYNNEKWPLINIS..GIQQEGv......tACDAA.HQPLMSDLQ....TLYSDN...PN....GSIETEFGWPVKs........nKYW...WAADR..A..EST..GY--....YQYLNLNTGGKGSD....SSTGS....yNAQVCL........................................
A0A4Z0L7R2_SALET/273-302 .............PDTPKASYWGHMAETLTDS...SGVAYKRPLL--.------.....------------------..------........-----.---------....------...--....------------..........---...-----..-..---..----....--------------....-----.....------s.......................................
Q8ZN56_SALTY/1723-1865 .............PDSDKAKYWGHMPETFTNS...KGVEFKRPLLRA.ELSSTA.....DTSGYTENNETWYTWSRY..PNMYQDt.....asPCDRL.GLPTVNDLQ....TLYTDY...PN....GALTTTLGLPVAs........gKYW...GAGNS..V..PDA..THSDs..qFQYVRLSDNNTLTT....KANTA.....TAQLCL........................................
W1IZ47_9GAMM/488-631 .............PDDDNATYWGHMPKTVTA-...GGKTFHRPQLAD.EKHL-E.....DKHGYEKNNETWLRMKWS..TVKEYCk.....ygNEFNS.VLPTIADAK....GLAEYN..lST....EDLYLYYGWPVKn.......gnNGYk.iWTSET..T..SKG..SKER....RAVVDLDTNTLG--....-----.....------dngsddpdkgeyfi..........................
Q8ZN55_SALTY/1728-1863 .............PDTPYASYWGHMPDTVQV-...NGVTLRRPYLKA.ELSAA-.....PRDTWPFNNEFWGTNYYY..QSEHVEts...lthLCGSQeNIASLDDLK....ALQSVI...--....GTLQ----WPTT..........SSW...DYVSQ..D..EGQ..SNKY....YCSFNETTGQTTCT....REKATt...sGLGSC-r.......................................
A0A447M0N3_SALBN/37-174 .............PDSDKAVMWGHMPETVTGN...GGVKFHRPLLAV.EAPS--.....GNGSYSINNESWSSVTAT..NMQKTGk......tGCDSD.YQPRYSDLQ....SLYDAN...PD....GALGTTYGWPIDg.......tnNYW...WASDE..D..AVT..ST--....YQTINLSNGAKHNT....TSPTT....yYRQVCL........................................
A0A068QMP7_9GAMM/898-1030 .............PDVSVAHFWGHMADTLVGK...NGVVFYRPRLKA.ELSAHL....aANDDIEENGEIWPRRTFQ..GAEWYC........KHIQK.KLPTKNDLM....ALYQAH...PN....NAIHDHLGWPER..........RSY...RSATP..E..KDE..----....HYAVNIAQGFEHVV....NDQVL.....DYVTCK........................................
A0A3S4E2Y8_SALBN/377-520 .............PDSDKAEMWGHMPPSLTAA...DGSQYQRPLLYN.ELSSTT.....NAVTFNEDNEVWAGFYGP..NSDKTNp......eSCGNG.YYPTASDLD....SLYSKY...PG....QAIKTTQGWPVN..........HSY...WSGTP..A..SAF..STSEp.ynYVTVDLGDGAHRSL....SNRAPg..dmQYQIC-r.......................................
Q8ZN56_SALTY/326-459 .............PDSSSANMYGHMAETSTATvdgASYTFYRPKLAA.ETDS--.....EDRTASINNETWAQFNWG..HADAHC........----D.ILPDARQLE....GLKIAR...--....GDLATTLGWPVGlt.....sgdEEY...WSSSQ..G..STA..TD--....HISIDMRSRALTQM....PDATQ.....SLVSCV........................................
A0A085HKG3_9GAMM/341-467 .............PDTDKATMWGHMAESASA-...NGYTFYRPKLAA.EASG--.....ADATIVDHNETWARFDWY..SAKGQC........----D.ILPDIRQLG....ALIVAQ...GS....HTVQESLGWPLQ.........dNYY...WSSSP..G..FSG..Y---....HEIVDMLNKSAESA....KDSEI.....HLASCV........................................
A0A085HKG2_9GAMM/329-468 .............PDTPKAHFWGHMPETITAS...GGLTFERPRLTA.ELPSPG.....EAGSVYLSGENWAELTFP..QAEKGV.......nGCASG.ALPFMKELK....ALYDEY...PS....GKLKKTFGLPD-..........RAY...WTGDA..K..RQG..STVS....RQIIQLSTGVKNTVslsnSNSTQ.....WMFMCL........................................
W1J0I8_9GAMM/1814-1947 .............PNTSLAKYWGHMTETVTA-...GKITFERPKLFE.ELKASGe..akDLVSTPVGKEDYPIGNWD..NISRHC........---TN.GIATIEETR....NLMEQE...--....TNMTDKYGWPGV..........-YY...TTSSY..E..LDS..AQAK...rFYRKNLETGNELFY....YGTSP....nHFVSCK........................................
A0A6H2FNX4_9ENTR/175-306 .............PNTLHAKMYGHMTDFLFV-...NGVKFERPVLAS.ERLG--.....-DQVFHYLNEDWSKFTWY..NGEAYC........KSRNA.RLPTKDELF....DFYKNH...SG....NDLLSNYGWPMV..........DRFnlvWTST-..-..---..----....--------------....-----.....------piinmyfpdplhfyinflnsdiekgitsnif.........
A0A2T3MV03_9GAMM/153-269 ........ysftf-------------------...NGLKYHQPRNIN.STKTM-.....PPMFINEKDNYWSRVNIS..SAESWC........KRFGL.RLPYFEELE....RLQSYG...--....QHLLLRYQWPTQ..........VNY...WSSSV..N..PLS..GE--....IKTLNLRNGKYDEY....RPPAL.....LYTTCV........................................
A0A656YFX4_SALNE/1-116 ............k-------------------...---TLHRPWLQA.EMLSGVt..pvFTNGVHANNEYWAMAHTV..DNTKWDi.....akQCGSLsKAPDNNDLL....TLYHSI...--....----SSLGWPTQ..........-GY...PYLSK..S..SSS..GG-M....YCGVDENTKSQNCAi..kPAGTA.....GYATCV........................................
A0A447M0N3_SALBN/320-453 .............PDSDKANYWGHMPETVQA-...NGKTLQRPLLLA.ELPAGI....tPPLHITMNNEVWSMAHTI..DASTWDl.....aaQCGSLaKAPVLKDLE....ELHTIF...--....----SDTGWPTS..........SSY...SYLSQ..S..PSG..KY--....YCGFNQTTGHDSCIi..dSKTTP.....GFAVCV........................................
Q8ZN55_SALTY/1431-1568 .............PDSDKANMYGHMPETFTAS...NGAEFKRPLVAG.EPSSEA.....HTDTYFETNENWIMVNSF..NTGNYG........GCPMN.QMAAIDDFT....ALYNDH...PS....GKVATDIGLPVG..........KRW...WAGDS..L..LKG..STLY....WQYKDLKTGKNYSM....SENPGn...yYLQLC-l.......................................
A0A085HKG3_9GAMM/1728-1870 .............PDSDKAAMWGHMPETFTNS...AGVEFNRPLLRA.ELSSTS.....DTSGLSANNEIWYTWSRY..PNLYFNs.....asPCDRL.GLPTMDDLQ....TLYNDH...PN....GELATEFGLPVAs........gAYW...GAGNS..I..PTD..DRRGs..qFQYIQLNNGATKAT....AANTA.....TAQLCL........................................
U3APT4_9VIBR/549-667 ........gdqhp-------------------...--ITFLKPEVIS.DDELDM.....QRSGYLENGQYWQSYTWS..EAEKYC........QQHGY.RLPTLSELD....QLDQMA...-G....GSIEAQFGWPST.........tYRY...WSSDR..A..SLD..GEHK....SRSMEIS-------....-----.....------gtgyedadwidlaalcv.......................
A0A2D0KTV7_9GAMM/874-1012 .............PDSQYANFWGHMADTATGA...NGRVFSRPLLQA.ELDAMGm...hGMTTYTENGEHWPRRIYR..GAVWYC........HKIHK.ELPTKEDLL....NLYQIH...QK....NEMHDLYGWPQF..........RSY...RSSTS..G..IDD..DGKK...aHYAVNIDDGTAHVI....NETVT.....DYVIC-i.......................................
A0A2V1H355_9GAMM/340-477 .............PDTPKANMWGYMQDLVTV-...NGVTFKRPFLYA.EIGKND....pSITSNLIEDEVWARFTFA..AAMATC........-----.TLPTQGQLK....SLANAY...PPvgtlTGITASLGWPSA..........EVY...RTLTP..Y..YDI..SVNQ....HYYVQMLDGSSTINr.ngGDDKP.....YNVTC-v.......................................
A0A4R1NDL5_9GAMM/1109-1234 .............PDVSAANYYGHMAESIDG-...----IARPRLAA.EITG--.....-GGSEMFNNEDWGTASYP..AAKALC........-----.SLPTIEKLS....DAYDVI...--....----KASGWPLLse.....astHGF...MWSSS..E..TAM..MGAAi..gVYALSTSNGSRLHTp..qLDGST.....GLVMC-v.......................................
A0A085HKG3_9GAMM/1152-1288 .............PDSDKATMWGHMPETVTAA...DGTVFKRPLLMA.ELPEGV.....SKNAYKENNEDWATVDFE..VIKDA-........-CGPA.YVPTLDAMQ....SLYDAW...PN....GAINLQKGWPVV.........gKAY...QTGTT..D..LTKsfDNRY....AKSINMENGSAKTS....LWNEK.....LYFVCQ........................................
A0A2U8I7G0_9GAMM/298-424 kelnftgrlnkih------------------R...NRITFLRPKLHSeELPSNR.....YHSPHIVDGEEWAKYLKD..SGIRK-........FCAPG.RIPTENEFK....HLHDEF...-S....PNVKQKIGWPVN..........QPY...WVISS..E..NGE..----....LKLYNLDSGTINNT....PSKRA....kALISC-i.......................................
A0A085HKG3_9GAMM/2582-2722 .............PDTDKARYWGHMPETVTNG...NGVKFHRPQLLA.EMPSDK....aNYSSYVSNGETWPAIAAS..KVESEGi......vNCSEA.YRPLFEELQ....SLYDRY...PA....GALNTQFGWPVDg.......qdNYW...WAVDA..D..EAT..HF--....RQALNLESGQKHTT....SSSSS....aYRQACL........................................
Q8ZN56_SALTY/869-1000 .............PDTPEAQMWGHMADTLTV-...GDMKFQRPKLAA.EATA--.....ATRTQEQDNETWARVSHA..DALNNPn.....agGCEAG.HLPRADQLA....ALYASS...DG....NKIHTVSGWPTE..........YDY...WSSTF..A..SAA..T---....WQAVSLAAGGYTAS....GDAS-.....DYVSCL........................................
A0A1I0AU25_9GAMM/552-685 .............PDSQYAKNWGHMADRVTV-...DNLVFLRPKLSK.EFPV--.....-ETSDSIGFEIWGKYTFR..EAQLLC........---GD.KLPTLSQLQ....TLYHAY...PD....SQLNTQLGWPIIkyg...tgnsNFY...WSQDK..T..ANE..VG--....FQALEFETGEIQGH....LENEK.....LYVTCM........................................
W1J0T3_9GAMM/1796-1934 .............PDTDQANYWGHMPNTLRSQ...NGNTFKRPRLRE.EVGSSA....rGHVGWSSSNESWAQFKHS..QAVSY-........-CGSG.YLPIWKDLT....SLYNSY...-G....NGIHSKTGWPTN..........DRY...WSATT..G..KTT..VPQG....YKAMDLSDGTNGPD....PDTSWdpaalLYVIC-l.......................................
A0A4Z0MG49_SALET/161-296 .............PDTDKALFWGNMADTTSV-...NGKTLHRPWLQA.ELLSGVt..pvFTNGVHTNNEYWAMAHTV..DNTKWDi.....akQCGSLsKAPDNNDLL....TLYHSI...--....----SSLGWPTQ..........-GY...PYLSK..S..TSS..GG-M....YCGVDENTRSQNCAi..kPASSA.....GYATCV........................................
Q8ZN55_SALTY/1141-1285 .............PDVSVARMWGHMAPSLTAA...DGAVYQRPLLYA.ELSSTD.....NTASKQETNETWAVFHGP..ASEGANp......aRCAAG.YYPAVEALD....SLYSKY...PS....RTINTAQGWPVY..........YSY...WSGSN..S..TSF..SSGAkldfYYAVDLADGSRRSE....NSATSt..awQYQIC-a.......................................
A0A085HKG3_9GAMM/2302-2439 .............PDTDKAQFWGHMPETVMSS...DGVEFHRPLLAA.EVQSKD.....GTFSSPGGNELWPLFNHNwpGLAEKT........ACGET.YQPTQEELK....TLYSDH...PN....GTLETLYGWPVSn.......asAGW...WALPE..P..YAW..M---....YPYVHLKTGATGTK....SSTDN.....QALVCL........................................
Q482D1_COLP3/884-1013 .........gdis-------------SVINA-...GDLVFTRPALAT.ETTL--.....DGGAATVEGNKWKLFNWS..EAEAYC........SDIGA.RLPTKTELSdnllTLVNDAdlvSN....GSFSATEHWPVN..........KGY...WASTF..P..EDG..KH-H....LMKTSIDPAKMSAL....ADTNR.....QYVTCV........................................
A0A4Z0KVL2_SALET/1-129 .............-----ANMYGHMADNSTATvdgESYTFSRPKLAA.ETDG--.....EDRAVSINNESWAQFNWA..NADKHC........----D.ILPDARQLE....GLKIER...--....GDLSTTLGWPVGlt.....sgdEEY...WSSSQ..G..AIA..AD--....HISIDMRSRSLTQM....PDATQ.....SLVSCV........................................
#=GC seq_cons .............PDostAphWGHMs-olss....sGhsFpRPhLtu.Ehsu.......tssshppsNEsWuphshs..supphs........tstts.plPshspLp....sLYssh...ss....sslpsphGWPst..........psY...huuot..s..tss..t.......attlslssGstssh....sssst.....thhsC.........................................
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