GenomeNet

Database: Pfam
Entry: KASH_CCD
LinkDB: KASH_CCD
Original site: KASH_CCD 
#=GF ID   KASH_CCD
#=GF AC   PF14662.6
#=GF DE   Coiled-coil region of CCDC155 or KASH
#=GF PI   CCDC155;
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   Jackhmmer:Q8N6L0
#=GF GA   33.90 33.90;
#=GF TC   33.90 33.90;
#=GF NC   33.80 33.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Coiled-coil
#=GF RN   [1]
#=GF RM   22826121
#=GF RT   A conserved KASH domain protein associates with telomeres, SUN1,
#=GF RT   and dynactin during mammalian meiosis.
#=GF RA   Morimoto A, Shibuya H, Zhu X, Kim J, Ishiguro K, Han M, Watanabe
#=GF RA   Y;
#=GF RL   J Cell Biol. 2012;198:165-172.
#=GF DR   INTERPRO; IPR028168;
#=GF DR   SO; 0001080; coiled_coil;
#=GF CC   This coiled-coil region is found in the central part of KASH or
#=GF CC   Klarsicht/ANC-1/Syne/homology proteins. KASH are a
#=GF CC   meiosis-specific proteins that localise at telomeres and
#=GF CC   interact with SUN1, thus being implicated in meiotic chromosome
#=GF CC   dynamics and homologue pairing [1].
#=GF SQ   158
#=GS A0A1B8XXD6_XENTR/266-376  AC A0A1B8XXD6.1
#=GS L9J9F2_TUPCH/129-282      AC L9J9F2.1
#=GS F6T9G8_ORNAN/1-137        AC F6T9G8.1
#=GS A0A1L8FNE7_XENLA/155-312  AC A0A1L8FNE7.1
#=GS L9LC95_TUPCH/97-150       AC L9LC95.1
#=GS A0A151NIZ3_ALLMI/326-516  AC A0A151NIZ3.1
#=GS H9GPA1_ANOCA/135-325      AC H9GPA1.1
#=GS F6WCS2_MACMU/157-347      AC F6WCS2.2
#=GS A0A2I4B1S8_9TELE/5-193    AC A0A2I4B1S8.1
#=GS A0A1V4JPZ4_PATFA/5-109    AC A0A1V4JPZ4.1
#=GS M3XU93_MUSPF/157-347      AC M3XU93.1
#=GS A0A1L8GVX1_XENLA/347-537  AC A0A1L8GVX1.1
#=GS G1QZ29_NOMLE/157-347      AC G1QZ29.1
#=GS S9WYT4_CAMFR/168-263      AC S9WYT4.1
#=GS M3ZWE9_XIPMA/362-552      AC M3ZWE9.1
#=GS I3MJN5_ICTTR/213-403      AC I3MJN5.2
#=GS L9J9F2_TUPCH/298-356      AC L9J9F2.1
#=GS W5M8B8_LEPOC/134-323      AC W5M8B8.1
#=GS U3JLP7_FICAL/335-525      AC U3JLP7.1
#=GS A0A1U7ST85_TARSY/143-333  AC A0A1U7ST85.1
#=GS A0A1U7RQA0_ALLSI/342-461  AC A0A1U7RQA0.1
#=GS V4BSY9_LOTGI/537-742      AC V4BSY9.1
#=GS L9LBX1_TUPCH/114-176      AC L9LBX1.1
#=GS A0A2B4SGT2_STYPI/156-271  AC A0A2B4SGT2.1
#=GS S7NHG0_MYOBR/156-297      AC S7NHG0.1
#=GS D3ZPX3_RAT/193-383        AC D3ZPX3.3
#=GS S9YYT3_CAMFR/92-282       AC S9YYT3.1
#=GS A0A1S3SFK2_SALSA/361-551  AC A0A1S3SFK2.1
#=GS A0A2I3GQF3_NOMLE/353-491  AC A0A2I3GQF3.1
#=GS A0A2K5MU77_CERAT/352-542  AC A0A2K5MU77.1
#=GS A0A1S3MZB8_SALSA/356-546  AC A0A1S3MZB8.1
#=GS A0A151MC24_ALLMI/232-423  AC A0A151MC24.1
#=GS A0A1S3HIV4_LINUN/183-372  AC A0A1S3HIV4.1
#=GS A0A1S3MZL1_SALSA/392-582  AC A0A1S3MZL1.1
#=GS G1T0P1_RABIT/9-122        AC G1T0P1.2
#=GS A0A2D0RT59_ICTPU/201-391  AC A0A2D0RT59.1
#=GS A0A2K5K115_COLAP/352-541  AC A0A2K5K115.1
#=GS A0A151NK38_ALLMI/70-260   AC A0A151NK38.1
#=GS A0A2I3RK37_PANTR/157-211  AC A0A2I3RK37.1
#=GS A0A2I4D8X1_9TELE/340-465  AC A0A2I4D8X1.1
#=GS A0A1W4XDV7_AGRPL/155-345  AC A0A1W4XDV7.1
#=GS A0A2I3SDW1_PANTR/352-542  AC A0A2I3SDW1.1
#=GS L5LRE4_MYODS/106-266      AC L5LRE4.1
#=GS F6SE11_HORSE/143-333      AC F6SE11.1
#=GS A0A151NIU0_ALLMI/326-516  AC A0A151NIU0.1
#=GS W5M8A1_LEPOC/127-317      AC W5M8A1.1
#=GS W5PTT2_SHEEP/157-347      AC W5PTT2.1
#=GS A0A1U8CM40_MESAU/231-406  AC A0A1U8CM40.1
#=GS U3J744_ANAPL/124-254      AC U3J744.1
#=GS G3H3D2_CRIGR/31-121       AC G3H3D2.1
#=GS A0A2I4CNV9_9TELE/340-530  AC A0A2I4CNV9.1
#=GS H0V519_CAVPO/187-373      AC H0V519.2
#=GS A0A091DTX3_FUKDA/113-250  AC A0A091DTX3.1
#=GS A0A2D0PT30_ICTPU/24-211   AC A0A2D0PT30.1
#=GS A0A2K5KEL0_COLAP/157-347  AC A0A2K5KEL0.1
#=GS A0A1V4JEL9_PATFA/322-495  AC A0A1V4JEL9.1
#=GS A0A1N7J8V4_9BACI/114-296  AC A0A1N7J8V4.1
#=GS M0QZW6_HUMAN/121-311      AC M0QZW6.1
#=GS A0A091DZP0_FUKDA/211-375  AC A0A091DZP0.1
#=GS G1M6G8_AILME/157-347      AC G1M6G8.1
#=GS A0A1S3NHH4_SALSA/120-309  AC A0A1S3NHH4.1
#=GS A1RYX0_THEPD/157-303      AC A1RYX0.1
#=GS A0A0M3JCV3_ANISI/26-149   AC A0A0M3JCV3.1
#=GS A0A1S3QPX0_SALSA/119-309  AC A0A1S3QPX0.1
#=GS A0A2G8KT51_STIJA/271-461  AC A0A2G8KT51.1
#=GS KASH5_MOUSE/227-417       AC Q80VJ8.3
#=GS W5PTT0_SHEEP/157-347      AC W5PTT0.1
#=GS A0A1B0GU45_HUMAN/352-542  AC A0A1B0GU45.1
#=GS A0A1U7RQA0_ALLSI/475-559  AC A0A1U7RQA0.1
#=GS A0A2I4CMJ1_9TELE/161-351  AC A0A2I4CMJ1.1
#=GS A0A067RG09_ZOONE/153-343  AC A0A067RG09.1
#=GS A0A0A0MUI8_PAPAN/157-347  AC A0A0A0MUI8.2
#=GS A0A151MC01_ALLMI/232-424  AC A0A151MC01.1
#=GS K7G5I4_PELSI/123-313      AC K7G5I4.1
#=GS H2QGU7_PANTR/157-347      AC H2QGU7.2
#=GS A0A096NPQ0_PAPAN/352-530  AC A0A096NPQ0.2
#=GS KASH5_HUMAN/157-347       AC Q8N6L0.2
#=GS A0A087XES9_POEFO/367-557  AC A0A087XES9.2
#=GS G3HZZ7_CRIGR/184-323      AC G3HZZ7.1
#=GS H2NZM7_PONAB/154-294      AC H2NZM7.1
#=GS B0JQU8_MICAN/43-229       AC B0JQU8.1
#=GS G3RJ62_GORGO/157-347      AC G3RJ62.1
#=GS H2R2N8_PANTR/352-542      AC H2R2N8.2
#=GS G1P3V9_MYOLU/27-217       AC G1P3V9.1
#=GS A0A2D0RS78_ICTPU/166-356  AC A0A2D0RS78.1
#=GS A0A226P3D1_COLVI/392-565  AC A0A226P3D1.1
#=GS S7N2G1_MYOBR/342-436      AC S7N2G1.1
#=GS A0A0Q3X885_AMAAE/349-547  AC A0A0Q3X885.1
#=GS A0A0D9S3K5_CHLSB/157-347  AC A0A0D9S3K5.1
#=GS M0R1C7_HUMAN/143-188      AC M0R1C7.1
#=GS H0WQ97_OTOGA/157-347      AC H0WQ97.1
#=GS A0A1V4JEZ8_PATFA/322-495  AC A0A1V4JEZ8.1
#=GS W5NE21_LEPOC/342-533      AC W5NE21.1
#=GS A0A1U8CU07_ALLSI/157-347  AC A0A1U8CU07.1
#=GS A0A0F8ASF9_LARCR/125-296  AC A0A0F8ASF9.1
#=GS A0A1U7RX27_ALLSI/342-532  AC A0A1U7RX27.1
#=GS A0A1S3MZ85_SALSA/392-582  AC A0A1S3MZ85.1
#=GS A0A2D0PRI7_ICTPU/24-217   AC A0A2D0PRI7.1
#=GS W5KAB3_ASTMX/17-134       AC W5KAB3.1
#=GS F6Y3J8_CANLF/157-347      AC F6Y3J8.1
#=GS G3QKQ4_GORGO/351-541      AC G3QKQ4.2
#=GS A0A151NIV3_ALLMI/317-507  AC A0A151NIV3.1
#=GS G5B8N4_HETGA/157-297      AC G5B8N4.1
#=GS U3J748_ANAPL/121-251      AC U3J748.1
#=GS A0A1U8CUU5_MESAU/185-375  AC A0A1U8CUU5.1
#=GS M3VWT5_FELCA/217-395      AC M3VWT5.2
#=GS A0A226MSR1_CALSU/347-514  AC A0A226MSR1.1
#=GS A0A2D0RS77_ICTPU/41-231   AC A0A2D0RS77.1
#=GS A0A2K5LPD9_CERAT/157-347  AC A0A2K5LPD9.1
#=GS A0A1S3G2K8_DIPOR/157-342  AC A0A1S3G2K8.1
#=GS A0A0P7V1K4_9TELE/341-531  AC A0A0P7V1K4.1
#=GS LRMP_DANRE/347-537        AC Q5RHB5.2
#=GS A0A1S3ITD9_LINUN/183-372  AC A0A1S3ITD9.1
#=GS A0A1V4JFT6_PATFA/322-495  AC A0A1V4JFT6.1
#=GS A0A1A6HA42_NEOLE/196-381  AC A0A1A6HA42.1
#=GS A0A1S3PSP8_SALSA/93-194   AC A0A1S3PSP8.1
#=GS G3TRB4_LOXAF/155-344      AC G3TRB4.1
#=GS A0A1S3MZ62_SALSA/392-582  AC A0A1S3MZ62.1
#=GS A0A1S3A9A8_ERIEU/455-645  AC A0A1S3A9A8.1
#=GS A0A1U8CX06_ALLSI/202-392  AC A0A1U8CX06.1
#=GS A0A096LTX1_POEFO/131-321  AC A0A096LTX1.1
#=GS A0A1U7RIS2_ALLSI/202-392  AC A0A1U7RIS2.1
#=GS G1NLQ9_MELGA/326-516      AC G1NLQ9.2
#=GS E9G4L4_DAPPU/164-289      AC E9G4L4.1
#=GS M3XKG7_LATCH/272-462      AC M3XKG7.1
#=GS A0A2D0PT40_ICTPU/24-220   AC A0A2D0PT40.1
#=GS A0A1U8CM34_MESAU/231-421  AC A0A1U8CM34.1
#=GS G3VM65_SARHA/152-344      AC G3VM65.1
#=GS A0A286Y9C0_DANRE/347-537  AC A0A286Y9C0.1
#=GS F1RHZ5_PIG/157-347        AC F1RHZ5.2
#=GS A0A1S3QAP7_SALSA/153-342  AC A0A1S3QAP7.1
#=GS M0QXW9_HUMAN/157-193      AC M0QXW9.1
#=GS A0A1U8CU20_ALLSI/202-392  AC A0A1U8CU20.1
#=GS A0A1L8FH44_XENLA/160-349  AC A0A1L8FH44.1
#=GS F7E6D8_CALJA/157-347      AC F7E6D8.1
#=GS A0A1U8CVX0_MESAU/231-418  AC A0A1U8CVX0.1
#=GS A0A2I3RK37_PANTR/209-304  AC A0A2I3RK37.1
#=GS M7AVP9_CHEMY/377-502      AC M7AVP9.1
#=GS A0A2D0RTR7_ICTPU/214-404  AC A0A2D0RTR7.1
#=GS A0A1U7S8G9_ALLSI/342-461  AC A0A1U7S8G9.1
#=GS G7PY71_MACFA/157-347      AC G7PY71.1
#=GS A0A2I4D8X1_9TELE/481-564  AC A0A2I4D8X1.1
#=GS W5NE18_LEPOC/342-532      AC W5NE18.1
#=GS L5L5J7_PTEAL/155-305      AC L5L5J7.1
#=GS KASH5_BOVIN/157-347       AC Q2T9R2.2
#=GS K7G5H8_PELSI/137-327      AC K7G5H8.1
#=GS W5MJN9_LEPOC/171-359      AC W5MJN9.1
#=GS A0A151MCA5_ALLMI/232-423  AC A0A151MCA5.1
#=GS A0A2D0RS75_ICTPU/214-404  AC A0A2D0RS75.1
#=GS F6Y3K9_CANLF/157-347      AC F6Y3K9.1
#=GS L5LES4_MYODS/247-341      AC L5LES4.1
#=GS A0A2D0T4M7_ICTPU/347-537  AC A0A2D0T4M7.1
#=GS W3XJI2_PESFW/44-206       AC W3XJI2.1
#=GS F6U4G4_ORNAN/1-137        AC F6U4G4.1
#=GS A0A1U8CJN0_MESAU/231-421  AC A0A1U8CJN0.1
#=GS A0A1S3N0K7_SALSA/392-582  AC A0A1S3N0K7.1
#=GS A0A1S3KVL2_SALSA/139-253  AC A0A1S3KVL2.1
#=GS A7S590_NEMVE/57-245       AC A7S590.1
A0A1B8XXD6_XENTR/266-376             dpekqdismdletyqaimkewiddcrnn-----------------------------------------------------..CSQQ....AITRARVLKEELEEMKTNMSSSEERKAQVVAQNKLL.........EKD...NL.SLIHKISGLQEE........N.............MRGTLEAEGLR..KSISE..ITDKVAILQ----------------...-----------------------.----------------..............................................
L9J9F2_TUPCH/129-282                 ...........................p-ATIDLLSSLEDLELSNRRLAGENAKLQRSVETAEEGSARLGEEILALRKQLR..STQQ....ALQSAKAVDEELEDLKTLAKSLEEQNRSLLAQARQM.........EKE...QQ.HLVTEMETLQEE........N.............GKLLAERDGVK..RRNEE..LATEKDTLKD---------------...-----------------------.----------------fgeveergslgkldaqr.............................
F6T9G8_ORNAN/1-137                   ............................-----------------------------------------------------..SSQQ....ALQVAKARDEELEDMKSLAKSLQEENRGLQAQARHS.........ERE...QQ.QFVAEVETLREQ........N.............GKLLAEHEGVK..MRSEV..LAAERMALKRQLCEYETLICHRDSI...LSERTSQTEDLTEAVEQYRATIQ.ELKSEIGHLEEKL---fl............................................
A0A1L8FNE7_XENLA/155-312             ...........................g-EHADFISKIRDLNFANKMLVDQKIKLQKSLETADETNSHLIEEISEVKSKLK..IFQQ....AVYHSRSLSNELEDLKAYTKSLEDKIAAFSSQKEGQ.........EKD...NL.SLSNQRQILQEE........I.............YNLLIEKEKSK..GNIDC..LSAEKEKMGHQISEYQRLISQKEML...LEE--------------------.----------------vsc...........................................
L9LC95_TUPCH/97-150                  ..........................la--ESDLTTYVTELHFNKQKLEEENNKFKLALETLEEVNSKLSEDCSELRLQIK..----....------------------------------------.........---...--.------------........-.............-----------..-----..-------------------------...-----------------------.----------------r.............................................
A0A151NIZ3_ALLMI/326-516             ...........................l-ETSDLITCVADLQFNNQKLQEENSKLKLVLESMEEANNRLMGDLEELHNQVK..SAQQ....TVMRTNSLKEELEEMKSNLNSLEEKRDKLLSQNKQL.........EKE...NQ.SLILKISDLQEE........N.............TRNALDADGLQ..KKILE..LAKNASELQMQIHVYETTVVNKDAS...LLQKDLDIKDLKSAIVEYTSIIE.TLRAEKNKLVYSMQQM..............................................
H9GPA1_ANOCA/135-325                 ...........................e-EAADLMNSIKDLQQGNKQLAVQNTKLQRTIETAEELNSRLSEEISELKGKLR..STQQ....ALEQARAVANELEDLKVFSKTLEEENNRLHAQTRQL.........EKE...QQ.LLFVRVDNLQEE........N.............KKLLTEKENSK..CKIKE..LFTKKASLKSKICEYEKLTSCKDAA...LNEKTKRIEELTMILDEYRTVVE.ELRLEVRRLQDHLCQ-s.............................................
F6WCS2_MACMU/157-347                 ...........................q-ATADLLSSLEDLELSNQRLAGENAKLQRSVETAEEGSARLGEEILALRKQLR..STQQ....ALQFAKAVDEELEDLKTLARSLEEQNRSLLAQARQA.........EKE...QQ.HLVAEMETLQEE........N.............GKLLAERDGVK..KRSQE..LAMEKDTLKRQLFECEHLICQRDTI...LSERTRHVESLAQTLQEYRVTTQ.ELRLEISRLEEQLSQT..............................................
A0A2I4B1S8_9TELE/5-193               .........................msq---KEMLERIAELDYNKSQLRDLNDEMRQWLEVADDDMAALRSENATLRKQLK..VMEE....IISEAQQVEAEPYGY-LMASDLNENRSSEKNIQDQ-.........EME...ST.MLKEENKKLTTK........M.............KNLEEEIDQEK..ITLSK..LRAAFQSLEDEMEEAQLELQHKQEV...IHQKNLEVDHLKETVEEYNNIIK.DLRLMKQELTQQLED-r.............................................
A0A1V4JPZ4_PATFA/5-109               ..........................gg-----------------------------------------------------..-SQQ....ALSLARVTSEELQELRAVVKGLQEKEQELRGHLRHL.........EKE...QQ.NLQGRVDELQEE........S.............QRLVAEGQQLR..PQVRA..LAAELTGLQAQLGSCSAQLSAQDLA...LA---------------------.----------------qvs...........................................
M3XU93_MUSPF/157-347                 ...........................p-TTADLLSSLEDLELSNRRLAGENSKLQRSLETAEEGSTRLGEEITTLRKQLR..STQQ....ALQCAKAVDEELEDLKTLAKGLEDQNRSLLAQARQT.........EKE...QQ.HLVAEMETLQEE........N.............GKLLAERDGVK..RRSEE..LATEKEVLKRQLYECERLICQRDAV...LSERTRHAESLAKTLEEYRTTTQ.ELRLEISHLEEQLSQT..............................................
A0A1L8GVX1_XENLA/347-537             ...........................l-ETSDLITCVADLQYNNQKLQEQHAKMKAINEALEEANHRLLEENEELYNQWK..SSQQ....AITRARVLKEELEEMKTNMNSSEERKAQVVALNKQL.........EKD...NL.SLIHKISSLQEE........N.............MRGTLEAEGLR..KTISE..ISDKVTVLQMQLSEAENALQKRDAT...LHMKELYIEELKSTLMDYALVIE.NLRTEKSKLENNLQQM..............................................
G1QZ29_NOMLE/157-347                 ...........................q-ATADLLSSLEDLELSNRRLAGENAKLQRSVETAEEGSARLGEEILALRKQLH..STQQ....ALQFAKAVDEELEDLKTLARSLEEQNRSLLAQARQA.........EKE...QQ.HLVAEMETLQLE........N.............GKLLAERDGVK..KRSQE..LAMEKDTLKRQLFECEHLICQRDTI...LSERTRRVESLAQTLEEYRVTTQ.ELRLEISRLEEQLSQT..............................................
S9WYT4_CAMFR/168-263                 ...........................l-EVSDLITYVTDLHFNKQKLEEENNKFKLALETLEEANSQLSQDCTELHLQIK..SAHQ....AIMRTNLLKEELEELKICMSASEEQKTMVIAQNKQL.........K--...--.------------........-.............-----------..-----..-------------------------...-----------------------.----------------dl............................................
M3ZWE9_XIPMA/362-552                 ...........................f-ETSELVYCVADLQMSNQKLQEEVRKLKQVVESMEESNQKLAEENEDLRNQAR..VTQQ....LAQKEKMLKEEVEEMKATLSCTEEGRARASAHSKHM.........ERE...NQ.SLITQIASLQEE........N.............FKITMETDELQ..NKIRE..LCDIIADLQLQNHSFDAVIGEKEAI...IVEKNRQINELKATVEEYSAITE.LLRKDKNKLETQMQMI..............................................
I3MJN5_ICTTR/213-403                 ...........................p-ATADLLSSLEDLELSNRRLAGENAKLQRSVETAEEGSARLTEEILALRRQLR..STQQ....ALQFAKAVDEELEDLKSLAKSLEEKNRGLLAQARQT.........EKE...QQ.YLVAEVETLQEE........N.............GKLLAERDGVR..RRSEE..LATEKDALKRQLYEYERLICQRDAI...LSERTRHTESLAKTLEEYRMTTQ.ELRLEISHLEEQLNQT..............................................
L9J9F2_TUPCH/298-356                 .........................lpw-----------------------------------------------------..----....------------------------------------.........---...--.------------........-.............-----------..-----..--------QRQLCECERLICQRDAI...LSERTQHAESLAKTLEEYRATAQ.ELRLEISQLEEQLSR-t.............................................
W5M8B8_LEPOC/134-323                 ...........................s-ESRDMISTVADLRHANHSLSEQNSSLLKAVEACDEKNLQLTAEVSKLKRKLM..STQR....SAVSFESLSEELDEARRLIKDSQERACRIKTYNNKL.........KKE...NE.CLRAQIQLLEEV........N.............EKLAQEKSFNK..TCLAK..LMKMQSEMRKELDETHVLLASKDRE...ITQKTMLIEELKFSQMENHRIIE.GMYSEVQRLQEN----arh...........................................
U3JLP7_FICAL/335-525                 ............................METSDLITCVADLQYNNQKLQEENNKLKVTLEAVDETNSKLLADNENLRQQLK..SVQQ....SVLKAKSLEEELEEARNNVNVSEEKREQVLLQNKQL.........EKE...NQ.SLNIKVTSLQEE........I.............IKNRMDNDGLQ..KKLLE..LSKNTAQLQIQAHVYESTVVNKEAS...LIQKEQDIKELKLAIVECSSIIE.TLRAEKNKLLENIQHM..............................................
A0A1U7ST85_TARSY/143-333             ...........................p-ATADLLSSLEDLELSNRRLAVENAKLQRSVETAEEGSARLGEEILTLRRQLR..STQQ....ALQFAKAVDEELEDLKSLAKSLEEQNRSLLAQARQT.........EKE...QQ.HLVSEMETLQEE........N.............GKLLAERDGVK..RRSEE..LAMEKDSLKRQLRECEHLICQRDTI...LSERTRHAENLTKTLEEYRVTTQ.ELRLEISHLEEQLSQT..............................................
A0A1U7RQA0_ALLSI/342-461             ...........................l-ETSDLIACVADLQFNNQKLQEENSKLKLVLESMEEANNRLMGDLEELHNQVK..SAQQ....TVMRTNSLEEELEEMKSNLNSLEEKRDKLLSQNKRL.........EKE...NQ.SLILKISDLQEE........N.............LE---------..-----..-------------------------...-----------------------.----------------tspdcti.......................................
V4BSY9_LOTGI/537-742                 ...........................q-ELSEMLSKIYDLQNQNLELIEENSKLQQHLDVQEENVATMSLDNKNLQKKVQ..SLQN....IMEERNEILSENEELKVKILNLQDTKKHLEDSIIKL.........EKE...NT.ELDTEVKNTENK........NgltlllseqretnIKLREVKLLQQ..TQIQEndLTLLLSEQRETNIKLREVKLLQQTQ...IQEKSEKLEKLENYIEELHQMNE.DIRADKSGLQQELIQ-a.............................................
L9LBX1_TUPCH/114-176                 ....................vrirdisg-----------------------------------------------------..----....------------------------------------.........---...--.------------........-.............-----------..-----..---------MQLNTYENTLLTKDAS...LRKKDLSIEELKSTIIEYGSIIE.NLRGDKKKLAQELQH-l.............................................
A0A2B4SGT2_STYPI/156-271             ..........................wd---SELMSTIETLQLNNKRLIEQQSAIQAQMENTEEGNNLLMAEVESLRKQLR..SAQL....TIEKNKGKEKENAELRQAVADAMEANQCLQTKITQL.........EKE...RT.LHEGNLKNIDEK........S.............P----------..-----..-------------------------...-----------------------.----------------rcssp.........................................
S7NHG0_MYOBR/156-297                 ...........................l-GTADLLSSLEDLELSNRRLAGENAKLQRSVETAEEGSARLGEEIVALRKQLR..STQQ....ALQFAKAVDEELEDLKSLAKSLEEQNRSLLAQARQT.........EKE...QQ.HLVAEMETLQEE........N.............GKLLAERDGVK..RRTEE..LVMEKDALKRTCH------------...-----------------------.----------------ae............................................
D3ZPX3_RAT/193-383                   ...........................p-ATAELLSSLEDLELSNRRLAGENAKLQRSVETAEEGSARLGEEITALRKQLR..STQQ....ALQVAKALDEELEDLKTLAKSLEEQNRSLMAQARHT.........EKE...QQ.HLVAEVETLQEE........N.............GKLLAERDGVK..RRSEE..LATEKDALKRQLCECERLICQREAA...LSERTRHAESLAQTLEEYRTTTQ.ELRQEISNLEEQLSQ-s.............................................
S9YYT3_CAMFR/92-282                  ...........................p-TTADLLSSLEDLELSNRRLVGENAKLQRSVETAEEGSARLREEILALRKQLR..STQQ....ALQFAKAVDEELEDLKTLAKSLEEQNRNLLAQARRT.........EKE...QQ.HLVAEMETLHEE........N.............GKLLAERDGVK..KRSEE..LAIEKDVLKRQLYECERLICQRDTI...LSERTRHMESLAKTLEEYKTATQ.ELKLEISHLEEQLSQT..............................................
A0A1S3SFK2_SALSA/361-551             ...........................l-ETSDLVFCVSDLQFSNQKLQQEVRKLKQSVETMEDHNQKLAEENEELKSQAR..LGQQ....LAQNEKMLKDEVEEMKMSLSCTEEGRARASAQSKHM.........ERE...NQ.SLIAKISCLQDE........N.............IKVTMEMDDLQ..KRMIE..LCDLNAELQVQNHSFDAVVNEKESL...ILQKCRQIEELKGAVVEYSSVTE.LLRADKTKLERQMHMM..............................................
A0A2I3GQF3_NOMLE/353-491             ..........................vv---SDLIAYVADLHFNKRKLEEENNKLKLALETLEETNSQLSEDCAKLRLQVK..SAHQ....AIMRTKLLKEELEELKLSMNASEEQKSMIVAQSKQL.........ETE...NR.ALILKIRILQEE........N.............IKNIMDIDRLE..KKIED..LSKTETEHQKG--------------...-----------------------.----------------ly............................................
A0A2K5MU77_CERAT/352-542             ...........................l-EVSDLIAYVADLHFNKQKLEEENNKFKLALENLEETNSQLSEDCTELRLQVK..SAHQ....AIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQL.........ETE...NR.ALILKIRILQEE........N.............IKNIMDIDRLE..KKIED..LSKTETEHQMQLHTYENTMLNKDTS...LQKKGLYIEELKSTIIEYGSIIE.NLRGDKNKLAHELQH-l.............................................
A0A1S3MZB8_SALSA/356-546             ...........................l-ETSDLVFCVTDLQFSNQKLQEEVRKLKQNVETMEDHNQKLAEENEELKSQAR..LGQQ....LAQKEKMLKDEVEEMKMSLSCTEEGRARASAQTKRM.........ERE...NQ.SLIVKMSCLQDE........N.............IKVTMEMDDLQ..KRMIE..LCDLNAELQVQNHSFDAVVSEKESL...IFQKCRQIEELKATVEEYSSVTE.LLRADKTKLESQIHMM..............................................
A0A151MC24_ALLMI/232-423             .......................mqfda-----LTSSVADLKYMYQKLTGQVLGTQKAMEVSDEICLQLMDEVAELKGKLT..RLEQ....YPVHLKCISNELEDFKSNLVSFCEENHMIHGYCRSL.........KKQ...VN.SLSTKLTSLEEE........L.............K-EKLDQSLLSmfVCLHP..FMESW---NKVIKTLEAIF-PKRAE...LSAKSTSIQDLE-----------.----------------lqkifleksnetddqsgrstaeaenqtitln...............
A0A1S3HIV4_LINUN/183-372             .........................dim----ELSNKVADLQYHNKKLTDENIKLQVQLENAEESSTLSAQEMEGLKKQLR..NMQR....IMEKNRELQHEVTDVKNSLALSEENTKVLQKKLAIT.........ERE...NS.NLEAQLDQLQKE........L.............IQTNCDLDAAK..TTHNE..LLGSLTDFKQLKAKFEEMGRVQEVQ...LSERCKETEEMKATLDQWKRISE.GLRQEKNELELQLIQ-t.............................................
A0A1S3MZL1_SALSA/392-582             ...........................l-ETSDLVFCVTDLQFSNQKLQEEVRKLKQNVETMEDHNQKLAEENEELKSQAR..LGQQ....LAQKEKMLKDEVEEMKMSLSCTEEGRARASAQTKRM.........ERE...NQ.SLIVKMSCLQDE........N.............IKVTMEMDDLQ..KRMIE..LCDLNAELQVQNHSFDAVVSEKESL...IFQKCRQIEELKATVEEYSSVTE.LLRADKTKLESQIHMM..............................................
G1T0P1_RABIT/9-122                   .............areeewnlcplsgag-----------------------------------------------------..----....-----------------------------------Q.........EKE...QQ.HLAAEVETLQEE........N.............GKLLAERDGVK..RRSEE..LATEKDALKRQLYECERLICQRDAV...LSERTSHAESLAKTLEEYRTTTQ.ELRLEISHLEQQLSQ-s.............................................
A0A2D0RT59_ICTPU/201-391             ..........................cd--AGDLLGLVAELKHAQRRLRGQNSSLLRSVSQCEETNLQLMMDVSELRSKLA..SAQL....YAGRARSLAEELDEARRALRESQEKTSRAQANCRSL.........MKE...IE.HLKAHIKVIEEM........N.............EKLLQERNGAE..DRLNK..LKRANADVREELEELQVLLAVKERE...ITKKNVTLQKLKETFLDYDRIVD.GLQCDLVRLQEHSQQ-a.............................................
A0A2K5K115_COLAP/352-541             ...........................l-EVSDLIAYIADLHFNKQKLEEENNKFTLALENLEETNSQLSEDCTELRLQVK..SAHQ....AIMRTNLLKEELEELKS-MNASEEQKSMIVAQSKQL.........ETE...NR.ALILKIGILQEE........N.............IKNIMDIDRLE..KKIED..LSKTEAEHQMQLHTYENTLLNKDTS...LQKKGLYIEELKSTIIEYGSIIE.NLRGDKNKLAHELQH-l.............................................
A0A151NK38_ALLMI/70-260              ...........................e-EAVALASIIEDLECSNKKLAVQNAKLQRTIESAEEINSWLTEEISELKGRLR..GMQQ....ALEQAKYIANELEDLKAIEKRLEEENVRLHTQAQQL.........EKE...QQ.CLSVQVDDLQEE........N.............RKLITEREGKR..QKIEV..LVTEKAELKSQLCEYERVISCKDAA...LTEKTNWAEELAATVEEYRMVVQ.EQRLEINRLQDHLCHT..............................................
A0A2I3RK37_PANTR/157-211             ...........................q-ATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLH..----....------------------------------------.........---...--.------------........-.............-----------..-----..-------------------------...-----------------------.----------------rw............................................
A0A2I4D8X1_9TELE/340-465             ...........................l-ETSELVHCIADLQMSIQKLQEEGKKLKKVVESMEESNQKLAEENEQLHNQAR..VNQQ....LAQKEKMLKEEVEEMKATLTSTEEGRARASAHSRHM.........ERE...NQ.SLIAKIASLQEE........V.............LQLNKKIN---..-----..-------------------------...-----------------------.----------------nqlslis.......................................
A0A1W4XDV7_AGRPL/155-345             .....................qeiaslq-------EATHELEHLNRKLQEELTLIKSQLAASEEHNELLQSDLKKINNKLL..AEQH....LNEQLHAERKENEELRECSQGLTKKIELLEKSFSCV.........ERE...NG.NIKQKLELLEQE........N.............QKLEDKLEQAR..NRELE..KEKTIIKMRTEYDFKEAVIASLEKA...VLEMQEKLKENQQIIEHHVEINE.GLKVEKITLEKLL---rgq...........................................
A0A2I3SDW1_PANTR/352-542             ...........................l-EVSDLIAYVADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVK..SAHQ....AIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQL.........ETE...NR.ALILKIRILQEE........N.............FKNIMDIDRLE..KKIED..LSKTETEHQMQLHTYENTLLNKDTS...LQKKGLYIEELKSTIIEYGSIIE.NLRGEKNKLAHELQ--ll............................................
L5LRE4_MYODS/106-266                 ...........................l-GTADLLSSLEDLELSNRRLAGENAKLQRSVETAEEGSARLGEEIVALRKQLR..STQQ....ALQLARAVDEELEDLKSLAKSLEEQNRSLLAQARQT.........EKE...QQ.HLVAEMETLQEE........N.............GKLLAERDGVK..RRTEE..LAMEKDALKRQLYECERLICQRDTD...LSE--------------------.----------------pqclne........................................
F6SE11_HORSE/143-333                 ...........................p-ATADLLSSLEDLELSNRRLAGENAKLQRSVETAEEGSARLGEEIVALRKQLR..STQQ....ALQFAKAVDEELEDLKTLAKSLEEQNRSLLAQARQT.........EKE...QQ.HLVAEVETLQEE........N.............GKLLAQRDEVK..RRSEE..LATEKDALKRQLYECERLICQRDAI...LSERTRHAESLAKTVEEYRTTTQ.ELRLEISHLEEQLSE-t.............................................
A0A151NIU0_ALLMI/326-516             ...........................l-ETSDLITCVADLQFNNQKLQEENSKLKLVLESMEEANNRLMGDLEELHNQVK..SAQQ....TVMRTNSLKEELEEMKSNLNSLEEKRDKLLSQNKQL.........EKE...NQ.SLILKISDLQEE........N.............TRNALDADGLQ..KKILE..LAKNASELQMQIHVYETTVVNKDAS...LLQKDLDIKDLKSAIVEYTSIIE.TLRAEKNKLVYSMQQM..............................................
W5M8A1_LEPOC/127-317                 ...........................i-ESRDMISTVADLRHANHSLSEQNSSLLKAVEACDEKNLQLTAEVSKLKRKLM..STQR....SAVSFESLSEELDEARRLIKDSQERACRIKTYNNKL.........KKE...NE.CLRAQIQLLEEV........N.............EKLAQEKSFNK..TCLAK..LMKMQSEMRKELDETHVLLASKDRE...ITQKTMLIEELKFSQMENHRIIE.GMYSEVQRLQKT----neet..........................................
W5PTT2_SHEEP/157-347                 .........................pap---ADLLSSLEDLELSNRRLAGENAKLQRSVETAEEGSARLGEEISALRKQLR..STQQ....ALQFARGMDEELEDLKTLAKSLEEQNRSLLAQARHT.........EKE...QQ.RLVAEMETLQEE........N.............GKLLAERDGVK..RRSEE..LASEKDILKRQLYECEHLICQRDAI...LSERTRHAESLTKTLEEYRATTQ.ELRLEISHLEEQLSQT..............................................
A0A1U8CM40_MESAU/231-406             ...........................p-ATAELLSSLEDLELSNRRLAGENAKLQHSVETAEEGSARLGEEIAALRKQLR..STQQ....ALQVAKALDEELEDLKTLAKSLEEQNRSLMAQARHT.........EKE...QQ.HLVAEVEILQEE........N.............GKLLAERDGVK..RRSVE..LATEKDALKRQLCECEQLICQREAV...LSERTRHAESLAQTLEEYRTTTQ.----------------v.............................................
U3J744_ANAPL/124-254                 ....................tldtrsvq----------EELERSNQHLASQNATLRRALESAEELNAQLAEEVAKLTEQLH..RAHQ....ALEHGWASSQKLEDLEDEVRQLQEEKRGLIEQNQRL.........ERE...QH.GLLEEVTGLQEM........N.............SALLAEAKGRK..ENLQ-..-------------------------...-----------------------.----------------apeaqkd.......................................
G3H3D2_CRIGR/31-121                  ...........................r-EMSDLIMCVEDLHSNKQKLEQENISCKLALEAMEEANRQLAEDCASLHLQMK..SAQQ....AVRRESLLKEELEDLKEMIAASEEQKTMALAQNK--.........---...--.------------........-.............-----------..-----..-------------------------...-----------------------.----------------..............................................
A0A2I4CNV9_9TELE/340-530             ...........................l-ETSELVHCIADLQMSIQKLQEEGKKLKQVVESMEESNQKLAEENEQLHNQAR..VNQQ....LAQKEKMLKEEVEEMKATLTSTEEGRARASAHSRHM.........ERE...NQ.SLIAKIASLQEE........N.............FKITTETDELQ..KKIKE..LCEINTDLQVQIHSLDAVISEKESV...TVEKSRQIDELKAAVEEYSAITE.LLRKDKNKLENQLQMI..............................................
H0V519_CAVPO/187-373                 ...........................s-ATADLLSTLEDLELSNRRLAGENAKLQRSVETAEEGSARLGEEILALRRQLR..STQQ....ALQSAKAVGEELEDLKTLAKSLEEQNRCLLAQARQT.........EKE...QQ.HLVAEVETLQEE........V.............SQGLAARASRR..LETDG..LLPWQ----RQLYECERLICQRDTI...LSERARHTESLTKTVEEYRATTR.ELRREISHLEEQLCQ-a.............................................
A0A091DTX3_FUKDA/113-250             ...........................p-ATAALLSSLEDLELSNRRLAGENAKLQRSVETAEEGSARLGEEILALRRQLR..STQQ....ALQSAKAVDEELEDLKTLAKSLEEQNRSLLAQARQT.........EKE...QQ.HLVAELETLQEE........N.............GKLLAERDGVK..RRSEE..LATEKDTLK----------------...-----------------------.----------------vl............................................
A0A2D0PT30_ICTPU/24-211              .....................sdkgtdk----------AELLHSNSCLRTLNTDLQKAAEMAEDSNVLLRSENSELKNQIK..SLKQ....SIQNVQPLVNELEEIRAAKTEKDEICEAIEANRKEL.........AKD...NQ.TLRQQVEALSSE........M.............SSFLLEKEQQE..KEITK..LSCALKALQQQLAENRLHLEQKDEL...INQRDFAIEQLKDSVSEYITIKQ.DMKEKLNDLEDQLA--la............................................
A0A2K5KEL0_COLAP/157-347             ...........................q-ATADLLSSLEDLELSNQRLAGENAKLQRSVETAEEGSARLGEEILALRKQLR..STQQ....ALQLAKAVDEELEDLKTLARSLEEQNRSLLAQARQA.........EKE...QQ.HLVAEMETLQEE........N.............GKLLAERDGVK..KRSQE..LAMEKDTLKRQLFECEHLICQRDTI...LSERTRHVESLAQTLQEYRVTTQ.ELRLEISRLEEQLSQT..............................................
A0A1V4JEL9_PATFA/322-495             ............................METSDLITCVADLQYNNQKLQEENNKLKLTLEAVDETNNKLLADNEDLQQQIK..SIQH....SVLKAKSLEEELEEAKNNLNLLEEKRQQILCQNKQL.........---...--.------------........N.............IRNSVDTDELK..KKILE..LSKNAAELQIQAHIYESTVVNKEAS...LIQKEQNIKELKLTIAEYSSIIE.TLRAEKSKLLEDMQHM..............................................
A0A1N7J8V4_9BACI/114-296             ..........................hn-----------SLQTSMGSLEEGHNSLQTSMSSLEEGHNSLQTSMDSLKEGHH..SLQT....SM---GSLEEGHNSLQTSMSSLEEGHNSLQTSMGSL.........EEG...HN.SLQTSMGSLEEG........H.............NSLQTGMGSLK..EGHHS..LQTSMDTLKEGHHSLKSEMHER---...-----------------------.----------------fdgveaklegvgkqfeqtnetrlneydfvlkkvndvekdvymlknk
M0QZW6_HUMAN/121-311                 ...........................q-ATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLH..STQQ....ALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQA.........EKE...QQ.HLVAEMETLQEE........N.............GKLLAERDGVK..KRSQE..LAMEKDTLKRQLFECEHLICQRDTI...LSERTRDVESLAQTLEEYRVTTQ.ELRLEISRLEEQLSQT..............................................
A0A091DZP0_FUKDA/211-375             ..........................rd--VSDLITYVADLHFHKQRLEEENHKFKLALETSEEANSQLTEDCAELRLQVK..SARQ....AIMRTNLLKEELEEMKISLTALEEQKSMAEAQNKQL.........ETE...NR.ALILKIRILQEE........N.............LKNALDIDGLE..KKIEK..LSETETEHQKDL-RIEELKS-----...-----------------------.----------------siieyrsitevccrftvcr...........................
G1M6G8_AILME/157-347                 ...........................p-ATAELLSSLEDLELSNRRLAGENAKLQRSVETAEEGSARLGEEIEALRKQLR..STQQ....ALQCAKAVDEELEDLKTLAKSLEEQNRSLLAQARQT.........EKE...QQ.HLVAEMETLQEE........N.............EKLLAERDGVK..RRSEE..LATEKEALKRQLYECERLICQRDAV...LSERTRHAESLAETLEEYRTRTQ.ELRLEISHLEEQLSQT..............................................
A0A1S3NHH4_SALSA/120-309             ....................saeersdv---------LAELVYSRSRLKQLNSELQRTVELADDNNTVLRTENAALRNQVK..GMKQ....SIHDAEQLMDELEEIRSLSAEKDGATGNLESYIKQL.........EKE...KE.ILEDQIETIGSE........M.............SRIIPDRATDK..KKIAD..LSQALQALQLRLEESRLTLDQRYEV...IHKKDFVVEQLEQSLIEYSSITQ.DLKEKMKDLESQLAE-a.............................................
A1RYX0_THEPD/157-303                 .................laeaqrkayea-----------------DRLAEQVSQLSQRVRSLEIALANESGKCSALGEQLR..SVSSewgaLKEKAGALKAENDALKARVSELESENARLRSELASL.........KEE...KG.SLASRLTSVQES........Y.............QSLLTELGSLR..QKYES..LSFVASALQAALVALAAV-------...-----------------------.----------------aava..........................................
A0A0M3JCV3_ANISI/26-149              ..........................va-----------------------------------------------------..----....------TLEGDLERTQSRLNTVEEQYNAAQLENNKL.........RAE...ID.TLNRQIDVLKNT........N.............ASQVSEIERLK..KKVTQ..LTDIN---KQQTDEIDKLRTERDQLdkaYREKAKQVEQLTDHVKTLESRID.RMRAEIQTL-------s.............................................
A0A1S3QPX0_SALSA/119-309             ...................lsaeersdv---------LAELVYSRSRLKQLNSELQRTVELADDNNTVLRTENAALRNQVK..GMKQ....SIHDAEQLMDELEEIRSLSAEKDGATGNLESYIKQL.........EKE...KE.ILEDQIETIGSE........M.............SRIIPDRATDK..KKIAD..LSQALQALQLRLEESRLTLDQRYEV...IHKKDFVVEQLEQSLIEYSSITQ.DLKEKMKDLESQLAE-a.............................................
A0A2G8KT51_STIJA/271-461             ..........................sr--EADLTNELEYFKFQVKKLSDQNSKLQNQMESTEENNSQLLNELDTVQKKLR..SSEL....ISHRSISIREQNKELQNAMSTMEISNMDTEQKYQVV.........VEE...RD.VLQLRVKNLMEE........I.............EQAYSDIDEKK..STIDE..MQQLMNKLEREFQVTQEKLALQSVE...LAEKSMQFEDIQEQVKELLTSKA.ALQTEKNHLEEKVCEM..............................................
KASH5_MOUSE/227-417                  ...........................p-ATAELLSNLEDLELSNRRLAGENAKLQRSVETAEEGSARLGEEITALRKQLR..STQQ....ALQVAKALDEELEDLKTLAKSLEEQNRSLMAQARHT.........EKE...QQ.HLAAEVETLQEE........N.............EKLLAERDGVK..RRSEE..LATEKDALKRQLCECERLICQREAV...LSERTRHAESLARTLEEYRTTTQ.ELRQEISNLEEQLSQ-s.............................................
W5PTT0_SHEEP/157-347                 .........................pap---ADLLSSLEDLELSNRRLAGENAKLQRSVETAEEGSARLGEEISALRKQLR..STQQ....ALQFARGMDEELEDLKTLAKSLEEQNRSLLAQARHT.........EKE...QQ.RLVAEMETLQEE........N.............GKLLAERDGVK..RRSEE..LASEKDILKRQLYECEHLICQRDAI...LSERTRHAESLTKTLEEYRATTQ.ELRLEISHLEEQLSQT..............................................
A0A1B0GU45_HUMAN/352-542             ...........................l-EVSDLIAYVADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVK..SAHQ....AIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQL.........ETE...NR.ALILKIRILQEE........N.............FKNIMDIDRLE..KKIED..LSKTETEHQMQLHTYENTLLNKDTS...LQKKGLYIEELKSTIIEYGSIIE.NLRGEKSKLAHELQH-l.............................................
A0A1U7RQA0_ALLSI/475-559             .........................qrg-----------------------------------------------------..----....------------------------------------.........---...--.-----------E........N.............TRNALDADGLQ..KKILE..LAKNASELQMKIHVYETTVVNKDAS...LLQKDLDIKDLKSAIVEYTSIIE.TLRAEKNKLVYSMQQM..............................................
A0A2I4CMJ1_9TELE/161-351             ...........................c-EGQDLSGAVAELKHANRKLSEQKSSLLRMLAQCEDVNLQLSAEVTELQTKLV..SVQR....SAIRARSLTEELEETHQMLKEAQERVIRTQGSFTEL.........TRE...VE.HLKIYIRELEDK........N.............EKLSFERSCAE..DNLNK..LRKVNTELRAEREETLLMLVLREKE...TIKKDIFLEKMKNFHLESHTMIE.ELQSELIKLEEHSH--qi............................................
A0A067RG09_ZOONE/153-343             ...........................v-ETNALMECVMELNYSKKRLEEQNEDLQTQLHASEDGYALLQKDYKKMCLKLS..SLQG....VMQQFHQLQKECEELKEAAVAAETAGVVLKLREQEL.........EKE...AR.VNRRQLSELENQ........K.............MELVLELEVSS..RKNQE..VQKTVTLQKMEIEQLLKQCRQHEHL...NGTQADHILELKGRVDELLSSVQ.HLQEDKQSLEV-----cllsm.........................................
A0A0A0MUI8_PAPAN/157-347             ...........................q-ATADLLSSLEDLELSNQRLAGENAKLQRSVETAEEGSARLGEEILALRKQLR..STQQ....ALQFAKAVDEELEDLKTLARSLEEQNRSLLAQARQA.........EKE...QQ.HLVAEMETLQEE........N.............GKLLAERDGVK..KRSQE..LAMEKDTLKRQLFECEHLICQRDTI...LSERTRHVESLAQTLQEYRVTTQ.ELRLEISRLEEQLSQT..............................................
A0A151MC01_ALLMI/232-424             .......................mqfda-----LTSSVADLKYMYQKLTGQVLGTQKAMEVSDEICLQLMDEVAELKGKLT..RLEQ....YPVHLKCISNELEDFKSNLVSFCEENHMIHGYCRSL.........KKQ...VN.SLSTKLTSLEEE........L.............K-EKLDQSLLSmfVCLHP..FMESW---NKVIKTLEAIF-PKRAE...LSAKSTSIQDLE-----------.----------------lqkifleksnetddqsgrstaeaenqtitlnv..............
K7G5I4_PELSI/123-313                 ...........................e-EAAALMSSIEDLEYGHKKLAMQNAKLQRTIEAAEEHSSRLTEEIFQLKSRLR..SSQQ....ALEQAKSVSNELEDLKVVAKSLEEENGKLHSQARQL.........EKE...QQ.CLSLQVNNLQEE........N.............RKLLTERDRVK..QKVAG..LAAEKSDLKTQLCEYETLLSCKDTA...LTETTNHAEELTAMLAEYKTVVQ.ELRLETSQLQEQLSQT..............................................
H2QGU7_PANTR/157-347                 ...........................q-ATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLH..STQQ....ALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQA.........EKE...QQ.HLVAEMETLQEE........N.............GKLLAERDGVK..KRSQE..LAMEKDTLKRQLFECEHLICQRDTI...LSERTRHVESLAQTLEEYRVTTQ.ELRLEISRLEEQLSQT..............................................
A0A096NPQ0_PAPAN/352-530             ...........................l-EVSDLIAYVADLHFNKQKLEEENNKFKLALENLEETNSQLSEDCTELRLQVK..SAHQ....AIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQL.........ETE...NR.ALILKIRILQEE........N.............IKNIMDIDRLE..KKIED..LSKTETE--HQV-STS---------...QILKGLYIEELKSTIIEYGSIIE.NLRGDKNKLAHELQH-l.............................................
KASH5_HUMAN/157-347                  ...........................q-ATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLH..STQQ....ALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQA.........EKE...QQ.HLVAEMETLQEE........N.............GKLLAERDGVK..KRSQE..LAMEKDTLKRQLFECEHLICQRDTI...LSERTRDVESLAQTLEEYRVTTQ.ELRLEISRLEEQLSQT..............................................
A0A087XES9_POEFO/367-557             ...........................f-ETSELVYCVADLQMSNQKLQEEVRKLKQVVESMEESNQKLAEENEDLRNQAR..LNQQ....LTQKEKMLKEEVEEMKATLSCTEEGRARASAHSKRM.........ERE...NQ.SLIAQISSLQEE........N.............FKITMETDELQ..NKIRE..LCDFNADLQLQNHSFDAVIGEKESI...IVEKNRQINELKAAVEEYSAITE.LLRKDKNKLETQIQM-i.............................................
G3HZZ7_CRIGR/184-323                 ...........................p-ATAELLSSLEDLELSNRRLAGENAKLQRSVETAEEGSARLGEEISALRKQLR..STQQ....ALQVAKALDEELEDLKTLAKSLEEQNRSLMAQARHT.........EKE...QQ.HLVAEVETLQEE........N.............GKLLAERDGVK..RRSEE..LATEKDALKRT--------------...-----------------------.----------------rh............................................
H2NZM7_PONAB/154-294                 .........................rpe-----------------------------------------------------..LTQQ....ALQFAKAVDEELEDLKTLARSLEEQNRSLLAQARQA.........EKE...QQ.HLVAEMETLQEE........N.............GKLLAERDGVK..KRSQE..LAMEKDTLKWQLFECEHLICQRDTI...LSERTRHVESLAQTLEEYRVTTQ.ELRLEISRLEEQLSQT..............................................
B0JQU8_MICAN/43-229                  ...........................q-SSSDLLAQVKGLDVAQSELKDENQQLHAKIIHIEQHSAQLQHKATDLENSLQ..SLQQ....AVHI---GEGEIEHLKTTAKEIEAEKAGLMEQLEGE.........KAQ...IT.SLEAQIQTLEQQ........K.............GEINRQFDLTK..KQTTS..LYSQIQTLEQDKTLLQQ-ELEKAEE...LRAKVADLEYKNQELSDLAAQIP.SLQGQIQTLEQNLAH-q.............................................
G3RJ62_GORGO/157-347                 ...........................q-ATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEILALRKQLH..STQQ....ALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQA.........EKE...QQ.HLVAEMETLQEE........N.............GKLLAERDGVK..KRSQE..LAMEKDTLKRQLFECEHLICQRDTI...LSERTRHVESLAQTLEEYRVTTQ.ELRLEISRLEEQLSQT..............................................
H2R2N8_PANTR/352-542                 ...........................l-EVSDLIAYVADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVK..SAHQ....AIMRTNLLKEELEELKLSMNASEEQKSMIVAQSKQL.........ETE...NR.ALILKIRILQEE........N.............FKNIMDIDRLE..KKIED..LSKTETEHQMQLHTYENTLLNKDTS...LQKKGLYIEELKSTIIEYGSIIE.NLRGEKNKLAHELQ--ll............................................
G1P3V9_MYOLU/27-217                  ...........................l-GTADLLSSLEDLELSNRRLAGENAKLQRSVETAEEGSARLGEEILALRKQLR..STQQ....ALQFAKAVDEELEDLKSLAKSLEEQNRRLLAQARQT.........EKE...QQ.HLVAEMETLQEE........N.............GKLLAERDGVK..RRTEE..LVMEKDALKRQLYECERLICQRDTD...LSERTCHAESLAKTLEEYRTTTQ.ELRLEISHLEEQLSQT..............................................
A0A2D0RS78_ICTPU/166-356             ..........................cd--AGDLLGLVAELKHAQRRLRGQNSSLLRSVSQCEETNLQLMMDVSELRSKLA..SAQL....YAGRARSLAEELDEARRALRESQEKTSRAQANCRSL.........MKE...IE.HLKAHIKVIEEM........N.............EKLLQERNGAE..DRLNK..LKRANADVREELEELQVLLAVKERE...ITKKNVTLQKLKETFLDYDRIVD.GLQCDLVRLQEHSQQ-a.............................................
A0A226P3D1_COLVI/392-565             ............................METSDLITCVADLQYNNLKLQEENNKLKLTLEAVDETNNKLLADNENLHQQIK..SIQH....SLLKAKSLEEELEEAKNNLNLLEEKRQKMLCQNKQL.........---...--.------------........N.............IRNSMDCDGLQ..KKILD..LSKNAAELQMQVHIYESTVVNKEAS...LNQKEQDIKELKLTIVEYSSIIE.TLRTEKSKLLEDMRHM..............................................
S7N2G1_MYOBR/342-436                 ...........................l-EVSDLITYVEELHFNKQKLEEENNQLKLALETLEEANSRLSEDCTELRLQIK..SAHQ....AIMRTNLLQEELEELKTSMSASEEQKTTIVAQNKQL.........---...--.------------........-.............-----------..-----..-------------------------...-----------------------.----------------me............................................
A0A0Q3X885_AMAAE/349-547             ............................METSDLIICVADLQYHNQKLQKENSKLKLTLEAVDETNNKLLADNEDLRQQIK..SIQH....SVLKAKSLEEELEEAKNNLNLSEEKRQQILWQNKQL.........EKE...NQ.SLIIKVTSLQEEvkeimilqN.............IRNSMDMDGLQ..KKILE..LSKNAAELQMQVHIYETTVVNKEAS...LIQKEQDIKELKLTIVECSSIIE.TLRAEKNKLLENVQHM..............................................
A0A0D9S3K5_CHLSB/157-347             ...........................q-ATADLLSSLEDLELSNQRLAGENAKLQRSVETAEEGSARLGEEILALRKQLR..STQQ....ALQFAKAVDEELEDLKTLARSLEEQNRSLLAQARQA.........EKE...QQ.HLVAEMETLQEE........N.............GKLLAERDGVK..KRSQE..LAMEKDTLKRQLFECEHLICQRDTI...LSERTRHVESLAQTLQEYRVTTQ.ELRLEISRLEEQLSQT..............................................
M0R1C7_HUMAN/143-188                 ...........................q-ATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLGEEI--------..----....------------------------------------.........---...--.------------........-.............-----------..-----..-------------------------...-----------------------.----------------l.............................................
H0WQ97_OTOGA/157-347                 ...........................p-ATADLLSSLEDLELSNRRLAGENAKLQRSVETAEEGSARLGEEILALRKQLR..STQQ....ALQFAKAVDEELEDLKTLAKSLEEQNRNLLAQARQT.........EKE...QQ.HLVAEMETLQEE........N.............GKLLAERDGVK..KRSEE..LATEKDTLKRQLCECERLICQRDAI...LSERTHHAESLAKTLEEYRMMTQ.ELRLEISCLEEQLSQ-s.............................................
A0A1V4JEZ8_PATFA/322-495             ............................METSDLITCVADLQYNNQKLQEENNKLKLTLEAVDETNNKLLADNEDLQQQIK..SIQH....SVLKAKSLEEELEEAKNNLNLLEEKRQQILCQNKQL.........---...--.------------........N.............IRNSVDTDELK..KKILE..LSKNAAELQIQAHIYESTVVNKEAS...LIQKEQNIKELKLTIAEYSSIIE.TLRAEKSKLLEDMQHM..............................................
W5NE21_LEPOC/342-533                 ...........................l-ETSDLVYCVADLQFNNQKLQDEVRKLKLAVDTMEETNNKLMEENEELKTQAK..SGQQ....SAMKEKLLKGELEEMKVTLNNMEENRARSVAQNKQM.........ERE...NQ.SLISKIASLQEE........N.............IKNMVDIDHLQ..KKMAE..LCAVNADLQMQVHSLDNIVGEKEAL...LCEKNAQIQELKSTIEEYSSVTDqLLRAEKNKLESHVEM-l.............................................
A0A1U8CU07_ALLSI/157-347             ...........................e-EAVALASIIEDLECSNKKLAVQNAKLQRTIESAEEINSRLTEEISELKGQLR..GMQQ....ALEQAKYIANELEDLKAIEKRLEEEKVRLHTQAQQL.........EKE...QQ.CLSVQVDDLQEE........N.............RKLITEREGKR..QKIEV..LGTEKAEMKSQLCEYERVISCKDAA...LTEKTNWAEELAATVEEYRMVVQ.EQRLEINRLQDHLCHT..............................................
A0A0F8ASF9_LARCR/125-296             .........................cdg---KDLLGTVAELKHAHRKLSEQNSSLLRTVAQCEDINLQLTLEITELRAKLA..SAQR....SASRARSLTDELEETRQVFKEAQERASRTQTSCTKL.........SNE...VE.CLKVHIRRLEDK........N.............EKLSFERTCSE..DSINK..LRKINTELRKDI-LMD---------...---------KMKSSHVENHNMIE.GLQSELMRL-------qehshqv.......................................
A0A1U7RX27_ALLSI/342-532             ...........................l-ETSDLIACVADLQFNNQKLQEENSKLKLVLESMEEANNRLMGDLEELHNQVK..SAQQ....TVMRTNSLEEELEEMKSNLNSLEEKRDKLLSQNKRL.........EKE...NQ.SLILKISDLQEE........N.............TRNALDADGLQ..KKILE..LAKNASELQMKIHVYETTVVNKDAS...LLQKDLDIKDLKSAIVEYTSIIE.TLRAEKNKLVYSMQQM..............................................
A0A1S3MZ85_SALSA/392-582             ...........................l-ETSDLVFCVTDLQFSNQKLQEEVRKLKQNVETMEDHNQKLAEENEELKSQAR..LGQQ....LAQKEKMLKDEVEEMKMSLSCTEEGRARASAQTKRM.........ERE...NQ.SLIVKMSCLQDE........N.............IKVTMEMDDLQ..KRMIE..LCDLNAELQVQNHSFDAVVSEKESL...IFQKCRQIEELKATVEEYSSVTE.LLRADKTKLESQIHMM..............................................
A0A2D0PRI7_ICTPU/24-217              ........................gtdk----------AELLHSNSCLRTLNTDLQKAAEMAEDSNVLLRSENSELKNQIK..SLKQ....SIQNVQPLVNELEEIRAAKTEKDEICEAIEANRKELvrkedrteyAKD...NQ.TLRQQVEALSSE........M.............SSFLLEKEQQE..KEITK..LSCALKALQQQLAENRLHLEQKDEL...INQRDFAIEQLKDSVSEYITIKQ.DMKEKLNDLEDQLA--la............................................
W5KAB3_ASTMX/17-134                  ...........................r-ETSDLVFCVADLQFNNQKLQEEVRKLKQTVEGMEETNQKLIEENEELKTQAK..MGQQ....LLQKERMLKEEVEEMKLSLSSSEEIRARASAQSKHM.........ERE...NQ.NLIMKISSLQEE........V.............Q----------..-----..-------------------------...-----------------------.----------------pllfyl........................................
F6Y3J8_CANLF/157-347                 ...........................p-ATADLLSSLEDLELSNRRLAGENAKLQRSVETAEEGATRLGEEITALRRQLR..STQQ....ALQCAKAVNEELEDLKTLAKNLEEQNRRLLAQARQT.........EKE...QQ.HLVAEMETLQEE........N.............GKLLAERDGVK..RRSEE..LATEKEALKWQLCECEHLICQRDAV...LSERTHHAEGLAKTLEEYRTTTQ.ELRLEISHLEEKLSQT..............................................
G3QKQ4_GORGO/351-541                 ...........................l-EVSDLIAYVADLHFNKRKLEEENNKFKLALETLEETNSQLSEDCTELRLQVK..SAHQ....AIMRTNLLKEELEELKLSMNASEELNSMIVAQSKQL.........ETE...NR.ALILKIRILQEE........N.............FKNIMDIDRLE..KKIED..LSKTETEHQMQLHTYENTLLNKDTS...LQKKGLYIEELKSTIIEYGSIIE.NLRGEKNKLAHELQH-l.............................................
A0A151NIV3_ALLMI/317-507             ...........................l-ETSDLITCVADLQFNNQKLQEENSKLKLVLESMEEANNRLMGDLEELHNQVK..SAQQ....TVMRTNSLKEELEEMKSNLNSLEEKRDKLLSQNKQL.........EKE...NQ.SLILKISDLQEE........N.............TRNALDADGLQ..KKILE..LAKNASELQMQIHVYETTVVNKDAS...LLQKDLDIKDLKSAIVEYTSIIE.TLRAEKNKLVYSMQQM..............................................
G5B8N4_HETGA/157-297                 ...........................p-ATTDLLSSLEDLELSNRRLAGENAKLQRCVETAEEGSARLGEEILALRRQLR..STQQ....ALQSAKAVDEELEDLKTLAKSLEEQNQSLLAQARQT.........EKE...QQ.HLVAEVETLQKE........N.............GKLLAERDGVK..RRSEE..LATEKDALKHALH------------...-----------------------.----------------t.............................................
U3J748_ANAPL/121-251                 ....................tldtrsvq----------EELERSNQHLASQNATLRRALESAEELNAQLAEEVAKLTEQLH..RAHQ....ALEHGWASSQKLEDLEDEVRQLQEEKRGLIEQNQRL.........ERE...QH.GLLEEVTGLQEM........N.............SALLAEAKGRK..ENLQ-..-------------------------...-----------------------.----------------apeaqkd.......................................
A0A1U8CUU5_MESAU/185-375             ...........................p-ATAELLSSLEDLELSNRRLAGENAKLQHSVETAEEGSARLGEEIAALRKQLR..STQQ....ALQVAKALDEELEDLKTLAKSLEEQNRSLMAQARHT.........EKE...QQ.HLVAEVEILQEE........N.............GKLLAERDGVK..RRSVE..LATEKDALKRQLCECEQLICQREAV...LSERTRHAESLAQTLEEYRTTTQ.ELRQEISNLEEQLS--ls............................................
M3VWT5_FELCA/217-395                 ...........................p-ATADLLSSLEDLELSNRRLAGENAKLQRSVETAEEGSARLGEEIAALRK-AA..STQQ....ALQCAKAVDEELEDLKTLAKSLEEQNRSLLAQARQT.........EKE...QQ.HLVAEMETLQEE........N.............GKLLAERDGVK..RRSEE..LATEKDALKVEP--LPPAIFTITFG...PSQRTQHAESLAKTLEEYRTMTQ.----------------vgrhren.......................................
A0A226MSR1_CALSU/347-514             ..........................rn--------TFEDLQYNNLKLQEENNKLKLTLEAVDETNNKLLADNENLHQQIK..SIQH....SLLKAKSLEEELEEAKNNLNLLEEKRQKMLCQNKQL.........---...--.------------........N.............IRNSMDSDGLQ..KKILD..LSKNAAELQMQVHIYESTVVNKEAS...LNQKEQDIKELKLTVVEYSSIIE.TLRAEKSKLLEDMRHM..............................................
A0A2D0RS77_ICTPU/41-231              ..........................cd--AGDLLGLVAELKHAQRRLRGQNSSLLRSVSQCEETNLQLMMDVSELRSKLA..SAQL....YAGRARSLAEELDEARRALRESQEKTSRAQANCRSL.........MKE...IE.HLKAHIKVIEEM........N.............EKLLQERNGAE..DRLNK..LKRANADVREELEELQVLLAVKERE...ITKKNVTLQKLKETFLDYDRIVD.GLQCDLVRLQEHSQQ-a.............................................
A0A2K5LPD9_CERAT/157-347             ...........................q-ATADLLSSLEDLELSNQRLAGENAKLQRSVETAEEGSARLGEEILALRKQLR..STQQ....ALQFAKVVDEELEDLKTLARSLEEQNRSLLAQARQA.........EKE...QQ.HLVAEMETLQEE........N.............GKLLAERDGVK..KRSQE..LAMEKDTLKRQLFECEHLICQRDTI...LSERTRHVESLAQTLQEYRVTTQ.ELRLEISRLEEQLSQT..............................................
A0A1S3G2K8_DIPOR/157-342             ...........................p-ATADLLSSLEDLELSNRRLAGENAKLQRSVETAEEGSARLGEEISALRKQLR..STQQ....ALQFAKAVDEELEDLKTLAKNLEEQNRSLLAQARQT.........EKE...QQ.HLVAEVETLQEE........N.............GKLLAERDGVK..RRSEE..LATEKDTLKRQLYEYERLICQRDAI...LSERTLHAESLAKTLEEYRTTTQ.ALAV------------ttneaas.......................................
A0A0P7V1K4_9TELE/341-531             ...........................l-ETSDLVYCVADLQFNNHKLQEEVRKLKQAAEAMEETNHKLLEEIEDLRMQAK..IGQQ....SAQKEKLLKEEVEEMKASLSALEESRARVSAQSKQT.........ERE...NQ.SLISKIASLQEE........N.............LKVAVEMDDLQ..KKMIE..LCDLNADLQVQIHSFDLVINEKDGL...LQEKSQQIEDLKTAVMEYSSIME.LLRAEKAKLESHMQMM..............................................
LRMP_DANRE/347-537                   ...........................l-ETSDLVFCVADLQLNNQKLQEEVRKLKQAVENMEDTNQKLIEENEELKTQAK..MGQQ....LLQKEKMLKEEVEEMKLSLTSSEESRAQAAAQRKQM.........ERE...NQ.SLISKIAALQEE........N.............MKVTLEAEELQ..KKMND..LCDLNADLQVQIHSFDAILADKESL...IQEKNKQMDELKVAVVEYSSVTE.LLRADKNKLESQMQMM..............................................
A0A1S3ITD9_LINUN/183-372             .........................dim----ELSNKVADLQYHNKKLTDENIKLQVQLENAEESSTLSAQEMEGLKKQLR..NMQR....IMEKNRELQHEVTDVKNSLALSEENTKVLQKKLAIT.........ERE...NS.NLEAQLDQLQKE........L.............IQTNCDLDAAK..TTHNE..LLGSLTDFKQLKAKFEEMGRVQEVQ...LSERCKETEEMKATLDQWKRISE.GLRQEKNELELQLIQ-t.............................................
A0A1V4JFT6_PATFA/322-495             ............................METSDLITCVADLQYNNQKLQEENNKLKLTLEAVDETNNKLLADNEDLQQQIK..SIQH....SVLKAKSLEEELEEAKNNLNLLEEKRQQILCQNKQL.........---...--.------------........N.............IRNSVDTDELK..KKILE..LSKNAAELQIQAHIYESTVVNKEAS...LIQKEQNIKELKLTIAEYSSIIE.TLRAEKSKLLEDMQHM..............................................
A0A1A6HA42_NEOLE/196-381             ...........................p-ATAELLSSLEDLELSNRRLAGENAKLQHSVETAEEGSARLGEEVAALRKQLR..STQQ....ALQVAKALDEELEDLKTLAKSLEEQNRSLMAQARHT.........EKE...QQ.HLVAEVETLQEE........N.............GKLLAERDGVK..RRSEE..LATEKDALKRTR-HAESLAQ----T...LEEYRTTTQPGPSTRAHALPSLQ.ELRQEISNLEEQLS--ls............................................
A0A1S3PSP8_SALSA/93-194              ..........................cd--SRELLAIVSELKYAHSRMSKQNNSLLRTVSQGEDTNLQLTVEITELSAKLA..SAQR....SARRTRSLVEELEDARRSLREAQERASQAQASSCKL.........EEL...EE.TL----------........-.............-----------..-----..-------------------------...-----------------------.----------------vm............................................
G3TRB4_LOXAF/155-344                 ...........................p-ATADLLSSLEDLELSNRRLAGENAKLQLCVHLSLCISAFLSL-ICPICPCPL..SAQQ....ALQFAKAVDEELEDLKTLAKSLEEQNRSLLAQARQT.........EKE...QQ.HLVAKMETLQEE........N.............GKLLAERDGMK..RRSEE..LATEKEALKWQLYECECLICQREAI...LSERTHHAESLVKTLEEYKATTQ.ELRLEISHLEEQLSQT..............................................
A0A1S3MZ62_SALSA/392-582             ...........................l-ETSDLVFCVTDLQFSNQKLQEEVRKLKQNVETMEDHNQKLAEENEELKSQAR..LGQQ....LAQKEKMLKDEVEEMKMSLSCTEEGRARASAQTKRM.........ERE...NQ.SLIVKMSCLQDE........N.............IKVTMEMDDLQ..KRMIE..LCDLNAELQVQNHSFDAVVSEKESL...IFQKCRQIEELKATVEEYSSVTE.LLRADKTKLESQIHMM..............................................
A0A1S3A9A8_ERIEU/455-645             ...........................p-AAAELLSSLEDLELSNRRLAGENAKLRRSVERAEEGSACLGEEIAALRKQLR..STQQ....ALQFAKSVDEELEDLKTLAKSLEEQNRSLLAQARQT.........EKE...QQ.HLVAEIETLQEE........N.............GKLLAERDGVK..RRSEE..LAVEKDALKRQLCECEQLICQRDAI...LSERTHDAENLARTLEEYRATTQ.ELRQEISHLEEQLSQT..............................................
A0A1U8CX06_ALLSI/202-392             ...........................e-EAVALASIIEDLECSNKKLAVQNAKLQRTIESAEEINSRLTEEISELKGQLR..GMQQ....ALEQAKYIANELEDLKAIEKRLEEEKVRLHTQAQQL.........EKE...QQ.CLSVQVDDLQEE........N.............RKLITEREGKR..QKIEV..LGTEKAEMKSQLCEYERVISCKDAA...LTEKTNWAEELAATVEEYRMVVQ.EQRLEINRLQDHLCHT..............................................
A0A096LTX1_POEFO/131-321             .........................sgk---KDLSDVVSDLKQARHHLSEQNSSLLRMLAQCEDENLQLSLEITELQTKLL..SSQR....SAVKAQSVTEELEETRQRLKEVQETASHTQTSFTQL.........TNE...TD.RLRFHIRVLEDK........N.............ERLSFERACAE..ERVNK..LTRANTELQAEHVETLALVMLKHKE...ITRKNILLDKMKNFHAENYKMIE.GLLSELRRLQEHS---hqq...........................................
A0A1U7RIS2_ALLSI/202-392             ...........................e-EAVALASIIEDLECSNKKLAVQNAKLQRTIESAEEINSRLTEEISELKGQLR..GMQQ....ALEQAKYIANELEDLKAIEKRLEEEKVRLHTQAQQL.........EKE...QQ.CLSVQVDDLQEE........N.............RKLITEREGKR..QKIEV..LGTEKAEMKSQLCEYERVISCKDAA...LTEKTNWAEELAATVEEYRMVVQ.EQRLEINRLQDHLCHT..............................................
G1NLQ9_MELGA/326-516                 ............................METSDLITCVADLQYNNLKLQEENNKLKLTLEAVDETNNKLLADNENLCQQIK..SIQH....SVLKAKSLEEELEEAKNNLNLLEEKGQKILCQNKQL.........EKE...NQ.SLLIKIASLQEE........N.............VRNSVDTDGLQ..KKILD..LSKNAAELQVQVHIYESTVVNKEAS...LIQKEQDIKELKLTIVECTSIIE.TLRAEKSKLLENMRHM..............................................
E9G4L4_DAPPU/164-289                 ........................fask-----------------------------------------------------..----....---------NEVTGLRRSM---AEMSSRMSSASAGH.........RAE...LE.YLQPAVTKLEGE........L.............IASQEEVTELH..RSMAE..MSSASAGLRAELEYLQPAVTKLEGE...LIASQEEVTELHRSMDEMSSAFA.GLRAELEYLQRHLK--se............................................
M3XKG7_LATCH/272-462                 ...........................l-GTADLISNIEDLEQANRKLAEQNAKLQATVEGSEEANAHLSEEISNLKGKLK..SSQH....ALQQARSVAEELEDLKGIVKRLEERKQGLQTHNWQL.........EKD...HQ.SLSVQLESLQEE........N.............CRLRAERECGK..RRTEE..LLTNTAELKNQLYEAQTLACSREVL...LLLKINQEEEMKMRVEEYSSIIQ.ELKAEIQRLQEQLNQT..............................................
A0A2D0PT40_ICTPU/24-220              .....................sdkgtdk----------AELLHSNSCLRTLNTDLQKAAEMAEDSNVLLRSENSELKNQIK..SLKQ....SIQNVQPLVNELEEIRAAKTEKDEICEAIEANRKELvrkedrteyAKD...NQ.TLRQQVEALSSE........M.............SSFLLEKEQQE..KEITK..LSCALKALQQQLAENRLHLEQKDEL...INQRDFAIEQLKDSVSEYITIKQ.DMKEKLNDLEDQLA--la............................................
A0A1U8CM34_MESAU/231-421             ...........................p-ATAELLSSLEDLELSNRRLAGENAKLQHSVETAEEGSARLGEEIAALRKQLR..STQQ....ALQVAKALDEELEDLKTLAKSLEEQNRSLMAQARHT.........EKE...QQ.HLVAEVEILQEE........N.............GKLLAERDGVK..RRSVE..LATEKDALKRQLCECEQLICQREAV...LSERTRHAESLAQTLEEYRTTTQ.ELRQEISNLEEQLS--ls............................................
G3VM65_SARHA/152-344                 ...........................p-ATAELLSNLEELELSNRRLAGENAKLQRSVETADEGAARLGEELASLRKQLRrlSSQQ....ALQFAKAVDEELEDMKSLAKSLEEKNRSLVAQARQT.........ERE...QQ.QLVAEVETLQEE........N.............GKLLAERDGVK..KRSEE..LVVEKEALRRQLCEYESLICHRDHV...LSEVSGGGHARGGQCARWAALPS.ELKQKISHLEEQLSQ-n.............................................
A0A286Y9C0_DANRE/347-537             ...........................l-ETSDLVFCVADLQLNNQKLQEEVRKLKQAVENMEDTNQKLIEENEELKTQAK..MGQQ....LLQKEKMLKEEVEEMKLSLTSSEESRAQAAAQRKQM.........ERE...NQ.SLISKIAALQEE........N.............MKVTLEAEELQ..KKMND..LCDLNADLQVQIHSFDAILADKESL...IQEKNKQMDELKVAVVEYSSVTE.LLRADKNKLESQMQMM..............................................
F1RHZ5_PIG/157-347                   ...........................p-ATADLLSSLEDLELSNRRLAGENAKLHRSVETAEEASAHLGEEILALRKQLR..STQQ....ALQFAKAMDEELEDLKTLAKSLEEQNRSLLAQARQT.........EKE...QQ.HLVAEMAILQEE........N.............GKLLAECDGVK..RRSEE..LATEKDALKRQLYECERLICQRDAI...LSERTRHAESLAKTLEEYRTTTQ.ELRLEISHLEEQLSQT..............................................
A0A1S3QAP7_SALSA/153-342             ....................sseerrdv---------LAELVYSRSRLKQLNSELQRTVEVADDNNTLLRTENTALLNQVK..GMKQ....SIHDAEQLMDELEEIRSLLVEKDEATGNLEAYIKQL.........EKE...KE.ILEDQIESIGSE........M.............SRIIPDRDTDK..KKIVN..LSQALQALQLRLEESRLALDHRDEV...LRKKDFVVEQLEQSLTEYSSIAQ.DLKEKMKDLQSQLAE-a.............................................
M0QXW9_HUMAN/157-193                 ...........................q-ATADLLSSLEDLELSNRRLVGENAKLQRSMETAEE-----------------..----....------------------------------------.........---...--.------------........-.............-----------..-----..-------------------------...-----------------------.----------------g.............................................
A0A1U8CU20_ALLSI/202-392             ...........................e-EAVALASIIEDLECSNKKLAVQNAKLQRTIESAEEINSRLTEEISELKGQLR..GMQQ....ALEQAKYIANELEDLKAIEKRLEEEKVRLHTQAQQL.........EKE...QQ.CLSVQVDDLQEE........N.............RKLITEREGKR..QKIEV..LGTEKAEMKSQLCEYERVISCKDAA...LTEKTNWAEELAATVEEYRMVVQ.EQRLEINRLQDHLCHT..............................................
A0A1L8FH44_XENLA/160-349             ........................ehay-----FVSKIRDLNFANKKLMDQKIKLQKSLETADETNSHLIEEISEVKSKLK..ISQQ....AVSHSRSLSNELEDLKAYTKSLEDKISAFGSQKEEL.........EKD...NL.SLSNQREMLQEE........I.............YNLLIEKDKLK..GNIDS..LTAEKGKMGHQISEYKRLISQKEML...LEDRNVQSHRLQSILEEHRLQVQ.VLKREKRLLHEQLL--qp............................................
F7E6D8_CALJA/157-347                 ...........................p-ATADLLSSLEDLELSNRRLAGENAKLQRSVETAEEGSAHLGEEILALRKKLR..STQQ....ALQFAKAVDEELEDLKTLTKSLEEQNRSLLAQTRQA.........EKE...QQ.HLMAEMETLQEE........N.............RKLLAERDAVK..RRSQE..LAVEKDTLKRQLYECEHLICQRDTI...LSERTRHVESLAQTLEEYRVTTQ.ELRLEISRLEEQLSQT..............................................
A0A1U8CVX0_MESAU/231-418             ...........................p-ATAELLSSLEDLELSNRRLAGENAKLQHSVETAEEGSARLGEEIAALRKQLR..STQQ....ALQVAKALDEELEDLKTLAKSLEEQNRSLMAQARHT.........EKE...QQ.HLVAEVEILQEE........N.............GKLLAERDGVK..RRSVE..LATEKDALKRQLCECEQLICQREAV...LSERTRHAESLAQTLEEYRTTTQ.E---------------rdaagaglsspl..................................
A0A2I3RK37_PANTR/209-304             .........................hrw-----------------------------------------------------..----....------------------------------------.........---...--.HLVAEMETLQEE........N.............GKLLAERDGVK..KRSQE..LAMEKDTLKRQLFECEHLICQRDTI...LSERTRHVESLAQTLEEYRVTTQ.ELRLEISRLEEQLSQT..............................................
M7AVP9_CHEMY/377-502                 ...........................e-EAAALMNSIEDLEYGNKKLALQNAKLQRTIEAAEELNSRLTEEISQLQGRLK..STQQ....ALEQAKSVANELEDLKAVAKSLEEEKGKLYSQARQL.........NR-...--.KLLTERDRVKQK........V.............AGLVAEKADLK..G----..-------------------------...-----------------------.----------------rkaear........................................
A0A2D0RTR7_ICTPU/214-404             ..........................cd--AGDLLGLVAELKHAQRRLRGQNSSLLRSVSQCEETNLQLMMDVSELRSKLA..SAQL....YAGRARSLAEELDEARRALRESQEKTSRAQANCRSL.........MKE...IE.HLKAHIKVIEEM........N.............EKLLQERNGAE..DRLNK..LKRANADVREELEELQVLLAVKERE...ITKKNVTLQKLKETFLDYDRIVD.GLQCDLVRLQEHSQQ-a.............................................
A0A1U7S8G9_ALLSI/342-461             ...........................l-ETSDLIACVADLQFNNQKLQEENSKLKLVLESMEEANNRLMGDLEELHNQVK..SAQQ....TVMRTNSLEEELEEMKSNLNSLEEKRDKLLSQNKRL.........EKE...NQ.SLILKISDLQEE........N.............LE---------..-----..-------------------------...-----------------------.----------------tspdcti.......................................
G7PY71_MACFA/157-347                 ...........................q-ATADLLSSLEDLELSNQRLAGENAKLQRSVETAEEGSARLGEEILALRKQLR..STQQ....ALQFAKAVDEELEDLKTLARSLEEQNRSLLAQARQA.........EKE...QQ.HLVAEMETLQEE........N.............GKLLAERDGVK..KRSQE..LAMEKDTLKRQLFECEHLICQRDTI...LSERTRHVESLAQTLQEYRVTTQ.ELRLEISRLEEQLSQT..............................................
A0A2I4D8X1_9TELE/481-564             ..........................lf-----------------------------------------------------..----....------------------------------------.........---...--.-----------Q........N.............FKITTETDELQ..KKIKE..LCEINTDLQVQIHSLDAVISEKESV...TVEKSRQIDELKAAVEEYSAITE.LLRKDKNKLENQLQMI..............................................
W5NE18_LEPOC/342-532                 ...........................l-ETSDLVYCVADLQFNNQKLQDEVRKLKLAVDTMEETNNKLMEENEELKTQAK..SGQQ....SAMKEKLLKGELEEMKVTLNNMEENRARSVAQNKQM.........ERE...NQ.SLISKIASLQEE........N.............IKNMVDIDHLQ..KKMAE..LCAVNADLQMQVHSLDNIVGEKEAL...LCEKNAQIQELKSTIEEYSSVTD.LLRAEKNKLESHVEM-l.............................................
L5L5J7_PTEAL/155-305                 ...........................p-ATADLLSSLEDLELSNRRLAGENAKLQRSVETAEEGSARLGEEIAALRKQLR..STQQ....ALQFAKAVDEELEDLKSLAKSLEEQNRSLLAQARQT.........EKE...QQ.HLVAEIETLQKE........N.............GKLLAERDGVK..RRTEE..LAMEKDALKELRLEISHL-------...-----------------------.----------------eeqlsq........................................
KASH5_BOVIN/157-347                  ...........................p-ATADLLSSLEDLELSNRRLAGENAKLQRSVETAEEGSARLGEEISALRKQLR..STQQ....ALQLARGVDEELEDLKTLAKSLEEQNRSLLAQARHT.........EKE...QQ.RLVAEMETLQEE........N.............GKLLAERDGVK..RRSEE..LASEKDILKRQLYECEHLICQRDAI...LSERTRHAESLTKTLEEYRATTQ.ELRLEISHLEEQLSQT..............................................
K7G5H8_PELSI/137-327                 ...........................e-EAAALMSSIEDLEYGHKKLAMQNAKLQRTIEAAEEHSSRLTEEIFQLKSRLR..SSQQ....ALEQAKSVSNELEDLKVVAKSLEEENGKLHSQARQL.........EKE...QQ.CLSLQVNNLQEE........N.............RKLLTERDRVK..QKVAG..LAAEKSDLKTQLCEYETLLSCKDTA...LTETTNHAEELTAMLAEYKTVVQ.ELRLETSQLQEQLSQT..............................................
W5MJN9_LEPOC/171-359                 ......................masksy--------NMAELVHARNRLAEENAEIQKSIEMTEETNAQLRSENTALKKQVK..SIKQ....SILQAEELGVELEEVQSALSESSITNTKLKMRVKQL.........ERE...NE.ILKDKIDCVTDE........M.............DNMLSEREVDK..KKIIH..LGSMLKVLENQLEEERLALNQKDEI...VLKKDFVIEQLKNSLSEYSSVVQ.DLRDKVKDLQNQLAEM..............................................
A0A151MCA5_ALLMI/232-423             .......................mqfda-----LTSSVADLKYMYQKLTGQVLGTQKAMEVSDEICLQLMDEVAELKGKLT..RLEQ....YPVHLKCISNELEDFKSNLVSFCEENHMIHGYCRSL.........KKQ...VN.SLSTKLTSLEEE........L.............K-EKLDQSLLSmfVCLHP..FMESW---NKVIKTLEAIF-PKRAE...LSAKSTSIQDLE-----------.----------------lqkifleksnetddqsgrstaeaenqtitln...............
A0A2D0RS75_ICTPU/214-404             ..........................cd--AGDLLGLVAELKHAQRRLRGQNSSLLRSVSQCEETNLQLMMDVSELRSKLA..SAQL....YAGRARSLAEELDEARRALRESQEKTSRAQANCRSL.........MKE...IE.HLKAHIKVIEEM........N.............EKLLQERNGAE..DRLNK..LKRANADVREELEELQVLLAVKERE...ITKKNVTLQKLKETFLDYDRIVD.GLQCDLVRLQEHSQQ-a.............................................
F6Y3K9_CANLF/157-347                 ...........................p-ATADLLSSLEDLELSNRRLAGENAKLQRSVETAEEGATRLGEEITALRRQLR..STQQ....ALQCAKAVNEELEDLKTLAKNLEEQNRRLLAQARQT.........EKE...QQ.HLVAEMETLQEE........N.............GKLLAERDGVK..RRSEE..LATEKEALKWQLCECEHLICQRDAV...LSERTHHAEGLAKTLEEYRTTTQ.ELRLEISHLEEKLSQT..............................................
L5LES4_MYODS/247-341                 ...........................l-EVSDLITCVEELHFNKQKLEEDNSQLKLALETLEEANSRLSEDCTELRLQIK..SAHQ....ALMRTNLLQEELEELKTSMSASEEQKTTIVAQNKQL.........---...--.------------........-.............-----------..-----..-------------------------...-----------------------.----------------me............................................
A0A2D0T4M7_ICTPU/347-537             ...........................l-ETSDLVFCVADLQFNNQKLQEEVRKLKQATEAMEETNQRLVEENEELKTQAK..TGQQ....LLQKERMLKEEVEEMKLTLSSSEENRVRASAQSKQM.........ERE...NQ.TLISKLASLQDE........N.............MKVSVEVTELQ..KKMQM..LYELNADLQDQAHSFDAAMTEKDTF...IQEKMRQIEELKAAVMEYSSVTE.LLRAEKSKLESQMQ--ll............................................
W3XJI2_PESFW/44-206                  .........................tey---NNLVEQNHSLVTENAKLSKEKDALKKELCQAENANRAWSAEAERLRD---..INGR....LSSDNDILRDENDRLRRSISSEDDHIKGFKRRIKVL.........EREareQErMTRAEIEDLTEN........L.............AKSNDVAHQWK..RKCEE..WMAKYDKLKRTLYDYEVTIAEQKDK...I----------------------.----------------dhlkhqlrr.....................................
F6U4G4_ORNAN/1-137                   ............................-----------------------------------------------------..SSQQ....ALQVAKARDEELEDMKSLAKSLQEENRGLQAQARHS.........ERE...QQ.QFVAEVETLREQ........N.............GKLLAEHEGVK..MRSEV..LAAERMALKRQLCEYETLICHRDSI...LSERTSQTEDLTEAVEQYRATIQ.ELKSEIGHLEEKL---fl............................................
A0A1U8CJN0_MESAU/231-421             ...........................p-ATAELLSSLEDLELSNRRLAGENAKLQHSVETAEEGSARLGEEIAALRKQLR..STQQ....ALQVAKALDEELEDLKTLAKSLEEQNRSLMAQARHT.........EKE...QQ.HLVAEVEILQEE........N.............GKLLAERDGVK..RRSVE..LATEKDALKRQLCECEQLICQREAV...LSERTRHAESLAQTLEEYRTTTQ.ELRQEISNLEEQLS--ls............................................
A0A1S3N0K7_SALSA/392-582             ...........................l-ETSDLVFCVTDLQFSNQKLQEEVRKLKQNVETMEDHNQKLAEENEELKSQAR..LGQQ....LAQKEKMLKDEVEEMKMSLSCTEEGRARASAQTKRM.........ERE...NQ.SLIVKMSCLQDE........N.............IKVTMEMDDLQ..KRMIE..LCDLNAELQVQNHSFDAVVSEKESL...IFQKCRQIEELKATVEEYSSVTE.LLRADKTKLESQIHMM..............................................
A0A1S3KVL2_SALSA/139-253             ..........................cd--SRELLATVSELKHAHRRMSKQNNSLLRTVSQCEDTNLQLTVEITELSAKLA..SAQR....SARRTRSLVDELEEARRALREAKERASQAQASSCKL.........TKE...CD.CLKAHIKVLEDK........I.............-----------..-----..-------------------------...-----------------------.----------------vstn..........................................
A7S590_NEMVE/57-245                  ...........................d-RAQEMMATIESLQANNKRLLDQYSSVQAQMDLTDELNAQLTAELTDLKKQMQ..ILQH....TSEKYKLLEKENADLRQSVSETQEVANSLQNRNSLL.........ERE...KQ.SLEENIQDLNVK........L.............TQSQSEISLLA..SQKKE..LTESI-GLQKQV-VFEELKNVREEF...AEESTTKTQYLNSVIAELTLANE.ELKLEKSRLEQVVAD-l.............................................
#=GC seq_cons                        .............................tsu-LlssltDLphuNp+LttENsKLppslEssEEssspLs-EhttL+pQl+..SsQQ....ulpps+slcEELE-hKshhpshEEpppplhuQs+ph.........E+E...pp.pLhsclpsLQEE........N.............tKlhhEp-slc..++.p-..LspppstLphQlhph-thlsp+-s....lpp+shphcpLttsl.EYpshhp.tL+.-hscLppphp................................................
//
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