#=GF ID LPD29
#=GF AC PF18847.5
#=GF DE Large polyvalent protein associated domain 29
#=GF AU Mistry J;0000-0003-2479-5322
#=GF AU El-Gebali S;0000-0003-1378-5495
#=GF AU Iyer LM;0000-0002-4844-2022
#=GF AU Aravind L;0000-0003-0771-253X
#=GF AU Burroughs AM;0000-0002-2229-8771
#=GF SE Iyer LM
#=GF GA 27.00 27.00;
#=GF TC 27.60 27.00;
#=GF NC 26.00 26.30;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Domain
#=GF RN [1]
#=GF RM 28559295
#=GF RT Polyvalent Proteins, a Pervasive Theme in the Intergenomic
#=GF RT Biological Conflicts of Bacteriophages and Conjugative Elements.
#=GF RA Iyer LM, Burroughs AM, Anand S, de Souza RF, Aravind L;
#=GF RL J Bacteriol. 2017; [Epub ahead of print]
#=GF DR INTERPRO; IPR041311;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This is an alpha and beta fold domain with conserved polar
#=GF CC residues that is found in polyvalent proteins of conjugative
#=GF CC elements [1].
#=GF SQ 101
#=GS A0A0U5BIW8_9BACL/3-95 AC A0A0U5BIW8.1
#=GS A0A060QDZ5_9PROT/138-226 AC A0A060QDZ5.1
#=GS A0A4S2T8M8_9ACTN/5-104 AC A0A4S2T8M8.1
#=GS A0A0M0GC77_SPOGL/108-200 AC A0A0M0GC77.1
#=GS A0A0D6PDG7_9PROT/6-125 AC A0A0D6PDG7.1
#=GS U6RDV5_9BACT/92-179 AC U6RDV5.1
#=GS A0A0M9YF38_9ACTN/96-191 AC A0A0M9YF38.1
#=GS A0A7J0B051_9BACT/92-179 AC A0A7J0B051.1
#=GS A0A086MRH9_9ACTN/97-196 AC A0A086MRH9.1
#=GS W1J6T2_9GAMM/134-220 AC W1J6T2.1
#=GS A0A2J6MNG2_9BURK/129-217 AC A0A2J6MNG2.1
#=GS A0A3N4ZDY5_9ACTN/4-103 AC A0A3N4ZDY5.1
#=GS A0A5J5GGS6_9BACL/4-87 AC A0A5J5GGS6.1
#=GS C5AP01_BURGB/32-128 AC C5AP01.1
#=GS R7PCB0_9CLOT/89-220 AC R7PCB0.1
#=GS A6LIN6_PARD8/92-179 AC A6LIN6.1
#=GS A0A559IDB9_9BACL/6-95 AC A0A559IDB9.1
#=GS R7ETR8_9BACE/92-179 AC R7ETR8.1
#=GS A0A0S3F5W8_9SPHN/153-241 AC A0A0S3F5W8.1
#=GS A0A4Q4Z8K3_9ACTN/32-126 AC A0A4Q4Z8K3.1
#=GS A0A1Y5JU32_9BACL/4-94 AC A0A1Y5JU32.1
#=GS A0A2T5ISE2_9GAMM/147-241 AC A0A2T5ISE2.1
#=GS E0UN47_GLOV7/10-99 AC E0UN47.1
#=GS C5A9B5_BURGB/44-140 AC C5A9B5.1
#=GS M0QMC1_9ACTN/4-104 AC M0QMC1.1
#=GS A0A069D685_9BACE/332-419 AC A0A069D685.1
#=GS A0A231QZR5_9BACL/4-94 AC A0A231QZR5.1
#=GS A0A430AW42_9ENTE/84-180 AC A0A430AW42.1
#=GS H1CZK9_9FIRM/4-69 AC H1CZK9.1
#=GS A0A1E3L172_9BACL/5-99 AC A0A1E3L172.1
#=GS A0A0A1H587_9BURK/4-97 AC A0A0A1H587.1
#=GS W4HDW9_9RHOB/25-119 AC W4HDW9.1
#=GS A0A1M5DDJ0_9CLOT/19-133 AC A0A1M5DDJ0.1
#=GS A0A374A076_9BACT/92-179 AC A0A374A076.1
#=GS W0EU49_9BACT/92-179 AC W0EU49.1
#=GS A0A086MRI9_9ACTN/15-105 AC A0A086MRI9.1
#=GS A0A1B0V057_9CAUD/3-114 AC A0A1B0V057.1
#=GS A0A0H4KGK3_9BACI/105-197 AC A0A0H4KGK3.1
#=GS A0A7D4ALK1_9BACT/109-208 AC A0A7D4ALK1.1
#=GS A0A3N2N3B5_9BACT/93-180 AC A0A3N2N3B5.1
#=GS A0A174Q6D3_9BACE/92-179 AC A0A174Q6D3.1
#=GS A0A3N2KSG6_9BACT/93-180 AC A0A3N2KSG6.1
#=GS A0A859PWV1_9ENTR/145-235 AC A0A859PWV1.1
#=GS A0A1Y4HKS8_9BACT/92-179 AC A0A1Y4HKS8.1
#=GS A0A1X9T3S2_9BACL/5-89 AC A0A1X9T3S2.1
#=GS R6DE15_9BACE/92-179 AC R6DE15.1
#=GS V8CTV1_9NOCA/4-104 AC V8CTV1.1
#=GS A0A7Z0DC27_9ACTN/12-110 AC A0A7Z0DC27.1
#=GS A0A2H4PB09_9CAUD/5-98 AC A0A2H4PB09.1
#=GS E7NS15_TREPH/84-190 AC E7NS15.1
#=GS A0A0H3UZM4_9CAUD/6-102 AC A0A0H3UZM4.1
#=GS Q9PBQ4_XYLFA/6-99 AC Q9PBQ4.1
#=GS A0A126P537_9BACT/109-208 AC A0A126P537.1
#=GS A0A2T4YX88_9BACL/2-160 AC A0A2T4YX88.1
#=GS A0A0F5JAQ1_9BACT/92-179 AC A0A0F5JAQ1.1
#=GS A0A1N7HE10_9NOCA/4-104 AC A0A1N7HE10.1
#=GS A0A7W7KFR4_9PSED/139-226 AC A0A7W7KFR4.1
#=GS A0A133VQE9_9EURY/15-120 AC A0A133VQE9.1
#=GS R7JNZ6_9BACT/92-179 AC R7JNZ6.1
#=GS A0A2S3ZSD2_ARTGL/5-98 AC A0A2S3ZSD2.1
#=GS A6L0Q7_PHOV8/92-179 AC A6L0Q7.1
#=GS S5WIU5_9CAUD/10-102 AC S5WIU5.1
#=GS A0A7W7GM88_9MICC/1-74 AC A0A7W7GM88.1
#=GS D4M158_9FIRM/88-188 AC D4M158.1
#=GS A0A849C4S9_9NOCA/2-77 AC A0A849C4S9.1
#=GS A0A3A4K8I0_9NOCA/2-91 AC A0A3A4K8I0.1
#=GS A0A268EC40_9BACI/107-199 AC A0A268EC40.1
#=GS A0A7L8V6N3_9PROT/3-118 AC A0A7L8V6N3.1
#=GS A0A7J0AYC8_9BACT/92-180 AC A0A7J0AYC8.1
#=GS A0A0U2X666_9ACTN/4-103 AC A0A0U2X666.1
#=GS A0A7W7KET0_9PSED/138-225 AC A0A7W7KET0.1
#=GS G2GF06_9ACTN/96-187 AC G2GF06.1
#=GS A0A0F5JT21_9BURK/7-100 AC A0A0F5JT21.1
#=GS A0A7W7KEU9_9PSED/134-221 AC A0A7W7KEU9.1
#=GS A0A3M9MH14_9MICO/15-103 AC A0A3M9MH14.1
#=GS A0A4R8XRM5_9MICO/5-105 AC A0A4R8XRM5.1
#=GS G9BW63_9CAUD/1-93 AC G9BW63.1
#=GS A0A060R8M2_9BACT/336-424 AC A0A060R8M2.1
#=GS A0A411YDS4_9ACTN/7-105 AC A0A411YDS4.1
#=GS A0A0M8STW1_9ACTN/99-189 AC A0A0M8STW1.1
#=GS A0A2V3PYH8_9BACT/83-180 AC A0A2V3PYH8.1
#=GS C5ANP5_BURGB/32-128 AC C5ANP5.1
#=GS A0A502G2W7_9PROT/153-239 AC A0A502G2W7.1
#=GS A0A368VL74_9BACL/8-98 AC A0A368VL74.1
#=GS A0A415DSW7_9BACT/92-179 AC A0A415DSW7.1
#=GS A0A7G6Z5W8_9MICO/5-105 AC A0A7G6Z5W8.1
#=GS G2H045_9ENTR/119-211 AC G2H045.1
#=GS V8CVB7_9NOCA/4-104 AC V8CVB7.1
#=GS D7V1G9_LISGR/58-149 AC D7V1G9.1
#=GS A0A4P8J444_9BURK/6-99 AC A0A4P8J444.1
#=GS T0IXT1_9SPHN/131-219 AC T0IXT1.1
#=GS A0A396MSZ0_9BACT/93-181 AC A0A396MSZ0.1
#=GS A0A4V6QHF0_9MICO/5-105 AC A0A4V6QHF0.1
#=GS F8XMH6_9PROT/1-77 AC F8XMH6.1
#=GS A0A0Q5N9X1_9MICO/5-105 AC A0A0Q5N9X1.1
#=GS A0A0N1CVM6_9MICO/1-81 AC A0A0N1CVM6.1
#=GS A0A6N9Q0D5_9BACL/2-98 AC A0A6N9Q0D5.1
#=GS A0A1C5FKN5_9ACTN/99-194 AC A0A1C5FKN5.1
#=GS A0A0V7ZCI7_9CYAN/5-96 AC A0A0V7ZCI7.1
#=GS C5A9B2_BURGB/4-106 AC C5A9B2.1
#=GS A0A328EJF5_9BACT/3-92 AC A0A328EJF5.1
A0A0U5BIW8_9BACL/3-95 ...dvv----EIAKQIRTVLKKEFP...ATKFSVRSERYSLg......aSIRVSWDGLPST.AT.....V..................STITDSFAK....vRYCDATGEI-----..............--------......---------------lsggnmfitaqasetdevraaimerm.......................................................................
A0A060QDZ5_9PROT/138-226 ....rd--GALAAKNIRKLLKAAFK...TTKFSVRKSEYG-........CIYVRWSEGPSE.DE.....V..................SEITDRFKT.....GTFDHYSDCARQED.............tPWSKSFGG......----AEYVFTSR---aea..............................................................................................
A0A4S2T8M8_9ACTN/5-104 ....va--TKYVSAELRSRLKAEFP...GAKFSVRTGTGTGs......aWISVSWTDGPDT.EA.....V..................DRIAAPLHG.....AHWDGSTDSYVQTN.............nEVTVTVDGkk..vtGKPIVDGINTHRDFS.................................................................................................
A0A0M0GC77_SPOGL/108-200 ......QDCKEIAKEIRSHIKKRFP...QCKFSVRVPYYG-........KINFEIKSSPFE.KGs..lyL..................NAIKGYCESl...lNAYKHTYSEAD---..............PYTDYAGV......-HNFYGYVEIDWEYT.................................................................................................
A0A0D6PDG7_9PROT/6-125 ..ikpa----ATAKLVRAALKKKFP...GIKFSVRIAGGS-........-LNVSWVDGPLA.SL.....V..................DEVVQSYSS.....TRFDCSIDMEYRVD..............NWLL----......---------------pdgsaivaedrgtlgqkgccqpahnpqpegaklvrffygysfcrrefs.................................................
U6RDV5_9BACT/92-179 .....q-HAPEIVGLVRAWLKETYP...GYKFSVRRENCH-........SIHIRLMKADFE.AF.....-..................TKESGKVQG.....DVNHHHIHSDK---..............SLTDRAKD.....vMVNICDFIMSYN---fd...............................................................................................
A0A0M9YF38_9ACTN/96-191 ....lt--MRATAEYLRRLLRRTFP...GVKFSVRCGRGHGmq....ryEITVGWSGGPSR.TA.....V..................ATVTAPLLA.....-QYGNPEQCR----..............--------......---------------pawiavtvggrrhfgepsasaihlnra......................................................................
A0A7J0B051_9BACT/92-179 ....qm--RGEIVEIIRKWLKETYP...RYKFSVTQNGYR-........SINIYLVKADFE.AF.....-..................TKESGLIYKd...iNHYHIETDR-----..............TITERARE.....vMLNVCDFTMSYN---yd...............................................................................................
A0A086MRH9_9ACTN/97-196 .....l-STKATAVYLRQLLRRTFP...GVKFSVRCGPKRAkeryleryEITVTWSGGPNR.TA.....V..................ATVTAPLLA.....SYRSPEECRPA---..............--------......---------------wvsvtvdgrrhygepgvlaihlnrt........................................................................
W1J6T2_9GAMM/134-220 ......YDTKEAIKNIRLDLKINFP...GIKFSVRMSKSS-........-VYISWGSESNItKE....vV..................GNLLAKFKT.....GSFDTYEDIHKNE-..............-YTPFNEV......-FGSVDYIS------lrv..............................................................................................
A0A2J6MNG2_9BURK/129-217 .....y-SGRLAAANIRIELKRAFP...GVKFSVRMTHYG-........AVSVHWTDGPRQ.AE.....V..................EALCRRYKA.....GRFNSMEDIYEHAV.............qPWHHVFGG......----LEYLSVS----rees.............................................................................................
A0A3N4ZDY5_9ACTN/4-103 ......IDTKHVAAELRNRLKDAFP...GVKFSVRKDTGTAs......aWISVRWTDGPSP.AE.....V..................EELTRPMQG.....AQFNGMEDRYESTD.............nTVTVTVKGrk..vtGRPLVNGINTHRDVS.................................................................................................
A0A5J5GGS6_9BACL/4-87 ..tqia----LTAQALRQALKEAFP...LTKFSVRSSAGC-........AINVSWTDLPSV.AA.....V..................EAITDKYKN.....VSYDHHTG------..............--------......---------------eilsgantyvfcnveyspeft............................................................................
C5AP01_BURGB/32-128 ..ltlv----DTAQLVQKILTEAFP...SCAFAVSVHSTGAg......tLLDVAWTDGPRA.DQ.....V..................GRFVHPLQA.....RRLAHGGRAVAVEH.............fTLTPVGYR.....tVRLAADRISLTRAFS.................................................................................................
R7PCB0_9CLOT/89-220 ......MSTTEISKTIKIYCKEKYP...TWKFSVTSEYFAGg......sSINISVMEAPEQ.IFdlescR..................KAYAEHLEAe..kaGYYGGCGLAMDIEKmla.......ddnmHWQLHSISdr.dkqYFTEYGFTVMED---vykfmqsynfddsdsmidyf.............................................................................
A6LIN6_PARD8/92-179 .....q-HAPEIVELIRAWFRETYP...GYKFSVRRENCH-........SIHIRLMKADFE.AF.....-..................TKESGKVQGd...vNHHHIASDK-----..............SLTDRAKD.....vMMNIYDFIMSYN---fd...............................................................................................
A0A559IDB9_9BACL/6-95 ....ic--GKETKRHIVEALKLVFP...GIKFSSRSSYDS-........-VRVSWTDGPLE.HD.....V..................EKVLNRFQS....yTRILDIDDRHEATG.............yEWKGIVYV......---GARHLDASR---qls..............................................................................................
R7ETR8_9BACE/92-179 .....q-HAPEIVELVRTWLKEIYP...RYKFSVRRENYN-........SIYIKLMSADFE.AF.....-..................TRESGKVQ-.....DHINHYNIERN--P..............DLTDRAKE.....vMLNVCDFVMSYN---fd...............................................................................................
A0A0S3F5W8_9SPHN/153-241 .....s-SGKLAAQNIRAELKAAFP...GIRFSVRKESWG-........SIRISWTDGPTE.SS.....V..................NEIVKKYQG.....GSFNGMDDIYEYAG.............sPWTTVFGG......----SKYVFTSRDHS.................................................................................................
A0A4Q4Z8K3_9ACTN/32-126 .....l-STKDTAALLRLELKRHFP...HGRFSVRVEHEWH.......gWIRVRVTNAPPS.-L.....V..................EEFTRQLEL.....LRYDTFDDDHWN-H..............ALTVEEAGkp..crMTNRVRSIKVEW---ad...............................................................................................
A0A1Y5JU32_9BACL/4-94 ....es--STETAKKIRAALRRAFP...GQTFSVRSSADS-........-VSVSWEDGPFV.PD.....V..................EDVLHAFQSy...eTRRSSGEDRREAVG.............yGWEGRRIV......---GAQYLRTSRRLS.................................................................................................
A0A2T5ISE2_9GAMM/147-241 .....l-ETKEGAKLLKKTLTKLFP...DTKFSVTMSRGTAy......gSVSVSWVDGASY.DL.....V..................DVIAQHFRG.....NGYDGMSDSSYNLN..............ALNADGQI......VDYGLGYVSISRGYS.................................................................................................
E0UN47_GLOV7/10-99 ....ve--VKEIAKEVKLELSQAFQ...GVKFSVKSTLDK-........-ITIAWTDGPTQ.KE.....V..................LPIAKKYLGi...kNNYADDTRLYE---..............PVKFRGKM......VSTYLEYVFTDRK--es...............................................................................................
C5A9B5_BURGB/44-140 ...lsl---VETAQLVQSILTESFG...NTRFYVKTQQTGNh......tRIHVEWVDGPTE.QQ.....V..................NKILLPLQSs..tpGTFGGLTPVEH--F..............RITPTGPQ.....kLSLSADRISVKRGF-s................................................................................................
M0QMC1_9ACTN/4-104 ......YTTKETAAALRTQLRTTWP...GVKFSVRCATGTAy......gWMRVAWVDGPDD.DQ.....V..................RAVCNHYES.....ERFDGMTDSYQQQP.............dPLVVTTPGel.pemVRYSCCGINTERVYT.................................................................................................
A0A069D685_9BACE/332-419 .....g--QKTAANNLRSLLKHKFP...ATKFSVRKHYYD-........SYIVEWNEGPSE.PQ.....V..................KEITRLFVD.....KGFDGMTDSSFSIT..............SPFIKRYG......---GIGHISIDRNI-s................................................................................................
A0A231QZR5_9BACL/4-94 .....e-SGTETAKKIRAALRRAFP...GQTFSVRSSADS-........-VLVNWEDGPFV.PD.....V..................EDVLHAFQSy...eTRRSSGEDRREAVG.............yGWEGRRIV......---GAQYLRTSRRLS.................................................................................................
A0A430AW42_9ENTE/84-180 .....l-GTKEIAANLRKYVKEVYP...TWKFSITCQFYSGg......sSISVAAMEAPYEiLE.....R..................DKIKDNCYV.....DFYDHEEGEDFKA-..............--------......---------------gginidihrmrdreempilndfgye........................................................................
H1CZK9_9FIRM/4-69 ...esv---EKTAKVIAALLKEKFP...DVHFDVEAEYPNGt......dRVVVRYTDGPAP.AL.....V..................DYYIDKFQT.....--------------..............--------......---------------mhplngnl.........................................................................................
A0A1E3L172_9BACL/5-99 .stpai-----AAKIARGILKKRFP...ATKFSVRANAYAL........TLSVSWDDGVMK.EH.....V..................TQAIEWLEK.....-DFVWENQEYNNS-..............--------......---------------lyityernlsperkaiihnrlvdekid......................................................................
A0A0A1H587_9BURK/4-97 ......FSTAETAAIIRKSLKEAFA...GIKFSVRSSVYSGg......sSISVRWTDGPSE.EQ.....V..................RGVVGHLCG.....GYFDGSIDYAG---..............SVYHMQEGk....eIRLENDHLFFNRDHS.................................................................................................
W4HDW9_9RHOB/25-119 ...vgl---TDTAKLIRGALKAKFP...RTKFSVRTSRFSGg......tSIDISWTDGPTA.EL.....V..................DSITGPFQS.....GGFDGMIDMAFSVG..............GW------......---------------lypdgtaafretsgtegsagm............................................................................
A0A1M5DDJ0_9CLOT/19-133 ......MTTTEIAKTIRMYCKERYP...TWKFSVTSKYFSGg......sEILICVMEAPEQ.IFdlkacR..................KAYTEHLENe..kmGYYGGRGLGMNIEKmla.......edrmRWQLHRISdn.ykeYFTEYAFSVLSDVY-s................................................................................................
A0A374A076_9BACT/92-179 ....qm--RGEIVEIIRKWLKETYP...RYKFSVTQNGYR-........SINIYLIKADFE.AF.....-..................TKESGLIYKd...iNHYHIGTDR-----..............TITERARE.....vMLNVCDFTMSYN---yd...............................................................................................
W0EU49_9BACT/92-179 .....q-SAPEITELVRTWLKETYP...RYTFSVRRDGYS-........SILVRLMKADFE.AF.....-..................TKESGKVQGd...iNHYNIQASD-----..............SLTDRAKE.....vMTNVRDFVMSYN---fd...............................................................................................
A0A086MRI9_9ACTN/15-105 .....l-TAPQTATHLRRMLWRSFP...GVRFSVSRKHGR-........MLTVSWSGGPCE.VE.....E..................ATVAAPLL-.....ADYTTPERRRA--Q..............PVTVTRFGrt..thG--------------tplvdaialrrr.....................................................................................
A0A1B0V057_9CAUD/3-114 .....y-ITTEEVAEMRARLKAAFPlkeGWKFSLTKEHHS-........SVNFRFMAGPHE.FM.....AfdvdqyshdpetpkcraqAEAMGKFK-.....AVTNGSVNHYWIAD..............HWTPESAA.....iLQKASDIIHLHH---wd...............................................................................................
A0A0H4KGK3_9BACI/105-197 .....q-EAKVIAKEIRAHIKKRFP...QCKFSVTVPYYG-........KINFTIKSSPFE.KGs..vyL..................NAVKEYCV-.....NLLNAYRHCYSPSD..............PYTDYAGS......-YNFYGYVEIDWEYT.................................................................................................
A0A7D4ALK1_9BACT/109-208 ......YTTAGTAQLIREALKKAFP...TVKFSVTSSSFANg......sSVDIAYTDGPSS.KQ.....V..................ERVYAPFSS.....GHFNSQEDLYEYHQ.............ePTAINEAGql..arVSYGAKYISDRRSYS.................................................................................................
A0A3N2N3B5_9BACT/93-180 .....q-SSREIVQIIRDWLKETYP...RYKFSVRRYNYS-........SIYVTLMSADFE.AF.....-..................TKESGYIH-.....CSINHYRVERE--K..............GLTDRAHE.....vMTNVKDFVMSYN---yd...............................................................................................
A0A174Q6D3_9BACE/92-179 .....q-SAPEITELVRAWLKETYP...RYTFSVRRDGYN-........SILIRLMKADFE.AF.....-..................TRESGKVQGd...iNHYNIQASD-----..............SLTDRAKE.....vMTNIRDFVMSYN---fd...............................................................................................
A0A3N2KSG6_9BACT/93-180 .....q-SSREIVEIIRNWLKETYP...KYKFSVRRDGYS-........SIHVTLMTADFE.AF.....-..................TKESGYIH-.....CSINHYRVERE--Q..............GLTDRARE.....vMTNVKDFVMSYN---yd...............................................................................................
A0A859PWV1_9ENTR/145-235 .....s-SGKLAAKNIRKELKQSFK...GVKFSVRNPHYG-........SVDVCWQDGPTC.EK.....V..................DAIINKYKD.....GHFNSMEDIYEYSS..............NPFNTVYG......---SAKYPDSSRTF-sda..............................................................................................
A0A1Y4HKS8_9BACT/92-179 .....q-HAPEIVGLVRTWLKETYP...KYRFSVRRSGYS-........SINIRLMTADFE.AF.....-..................TKESGKVQGd...iNHYHIASDM-----..............SLTDRAKE.....vMTNVRDFVMSYN---fd...............................................................................................
A0A1X9T3S2_9BACL/5-89 ....en--ATATARKIRKVLKQRFP...ETAFIVRSAKDA-........-VNVDWTDGPLE.ED.....V..................TAAVGWMES.....KR-SSQ----DPEI..............GYSWEGKS......-CCGAEYIFTHRTI-s................................................................................................
R6DE15_9BACE/92-179 .....q-HAPEIVELVRTWLKETYP...RYRFSVRRENYN-........SIYIKLMSADFE.AF.....-..................TKESGKVQ-.....DTINHYNIEWN--P..............DLTDRAKE.....vMMNVCDFVMSYN---fd...............................................................................................
V8CTV1_9NOCA/4-104 ......FTTKETAAELRKHLRATWP...TVKFSVRCERGTGs......aWLRVAWVDGPAN.LQ.....A..................QNEWFGFQS.....AQFNGMTDSYDQLD.............dRLVCTDPAel.pevRSYSCDGINGVRAF-t................................................................................................
A0A7Z0DC27_9ACTN/12-110 .....y-NVKKTAQQIRTTLRTSYP...DTSFRVRMSRGTGy......gWLDIAWTDGPTE.PA.....V..................MELTARFQS.....ARFDSTADSYQPML.............pELYLIDGVp...teIRYHCRGISTARTYS.................................................................................................
A0A2H4PB09_9CAUD/5-98 .....i-SVTDTAKIVRGELKKHFP...GVVFSVRSSSYSMg......aSIDISWTDGPIA.KA.....V..................EAITGQFEG.....SSFDSMQDM-KISR..............RGTWEGRE......VRWGSDYVTPTRKYS.................................................................................................
E7NS15_TREPH/84-190 .....l-RNKDITAIIRDYIKYVHP...TYKFSVSTTDNR-........-IDIALMEHPIE.FTnr.elV..................EGYVKSLPPd..erCFVPSLNDKLRRCQltkkq....reefiEWTIQTSG......-RCELGFGALHKGL-c................................................................................................
A0A0H3UZM4_9CAUD/6-102 ...dvv----QVAKQIRKELKEKFP...FVKFSVRSSRYSGg......sSVHVSWTDFPTQ.ET.....V..................EKIVNKYKQ.....VRYDEYTGEI----..............--------......---------------lsggnlfviaqnkwsdelrnkietemknny...................................................................
Q9PBQ4_XYLFA/6-99 ......FTCAETAKLVRKALKESFP...DIKFSVKSSNYSGe......aSIRLKWIDGPNF.KQ.....I..................KPISKCFKS.....SYFDGSIDYKG---..............SIYHIMQGq....iVRFGADFVLHHRDYS.................................................................................................
A0A126P537_9BACT/109-208 ...ytv---AGTAQLIREALKVAFP...EVKFSVTSDSFANg......tSVRIAYTDGPTR.KQ.....V..................EQVYAAFES.....GQYNSQEEIYEYRR.............ePMTIDNSGql..frMSYGAKYISESRSYS.................................................................................................
A0A2T4YX88_9BACL/2-160 ....ak--ATEVAKKIRKVLKEQFP...GTKFSVRTDQYSMg......aSIIIKWTNFPTE.QT.....V..................DKVVRPYEQ....vS-RD----------..............--------......---------------pitgdilsggnlhisavnkwtselreeiekemphhikrsdleyyryfretsekvyeryrerieaptnrgqvmkdpegavtirqkmalhratglntte
A0A0F5JAQ1_9BACT/92-179 ....qm--RGEIVEIIRKWLKETYP...RYKFSVTQNGYR-........SINIYLVKADFE.AF.....-..................TKESGLIYKd...iNHYHIGTDR-----..............TITERARE.....vMLNVCDFTMSYN---yd...............................................................................................
A0A1N7HE10_9NOCA/4-104 ......FTTKQTAAEIRKHLRATWP...GVKFSVRCDRGTAs......sWIRVSWTDGPTD.QQ.....V..................RHETHQFQG.....AQFNGMTDSYDDLG.............eALVCTNPAel.pevRRYYCDGINTSRDIS.................................................................................................
A0A7W7KFR4_9PSED/139-226 .tdyaa-----ASANIRKELRKRFA...GTKFSVQLTMHA-........VAQISWRGGPSL.AE.....V..................KSATVAFQS....aRKVGEGVDTRN-TD..............TAFNE---......---------------afggleylsytrae...................................................................................
A0A133VQE9_9EURY/15-120 ....lg--TKEIAKRIRKQLKKEFP...DCKFSVRIKRYSGg......sSITVSFMKADRK.--.....V..................KMDFDKIPQ.....GWFNRYLDIRSIEDlrklqnedyhqlnqHTLKQEYG......-GHWCNGVFLTRQ--gh...............................................................................................
R7JNZ6_9BACT/92-179 .....q-SAPEITELVRAWLKETYP...RYTFSVRKDGYS-........SILIRLMKADFE.AF.....-..................TRESGKVQGd...iNHYNIQASD-----..............SLTDRAKE.....vMTNVRDFVMSYN---fd...............................................................................................
A0A2S3ZSD2_ARTGL/5-98 .....v-SATDTAKLVKRTLKAQFP...DTKFSVRTLKYAGg......aTVDVEWVHGPTT.PA.....V..................DAIVKDFEG.....TAPDATGDFSD---..............PITHTKDGq....qIHYGARHIHTRRM--it...............................................................................................
A6L0Q7_PHOV8/92-179 .....q-HAPEIVALVRAWLKETYP...GYKFSVRRENCH-........SIHIRLMKADFE.AF.....-..................TKESGKVQGd...vNHYHIDSDK-----..............YLTDRAKD.....vMMNICDFIMSYN---fd...............................................................................................
S5WIU5_9CAUD/10-102 ltpnes------GKAIRAELKSKFP...NIKFSVKKDGAN-........TYGVSWTDGPNS.KE.....V..................ENSIGRFRG.....KTFNFNTGMVENIE..............YIVEYNGQ.....fYRSGVGYLFLKRTLS.................................................................................................
A0A7W7GM88_9MICC/1-74 .....m-------------------...-TKFRVRMARGTAa......gWVNVEWTDGPDH.LH.....V..................MALLSMFES.....SQHEAPACEG--AS..............PWRICAGE......AHWVREGIVTSREI-s................................................................................................
D4M158_9FIRM/88-188 .....r-TLKEVAQIVRTYVKEKYP...TYKFSVRTSYASMc......kELHVTLKESPIP.--.....I..................YKTFEELTN.....DDFEKIGKSLF---..............PWNWVVDE......---RMNFLNASR---eekekiirdstnayknv................................................................................
A0A849C4S9_9NOCA/2-77 ...mei---PEAAKRWKQALRAHWP...GVRWSVRSAPRGW.......fTVITTWQDGPTT.SA.....V..................AAFCHEWK-.....--------------..............--------......---------------viqpdaaswirdsgfrrsys.............................................................................
A0A3A4K8I0_9NOCA/2-91 ..meip----AAAKLWKQALRAQWP...GVRWSVRSAPRGW.......fTVITMWEDGPTA.SA.....V..................ALFCQAWKT.....--------------..............--------......---------------vypdaatwiresgfrrsyspagyatvidaitre................................................................
A0A268EC40_9BACI/107-199 ......QDAKEIAKEIRSHVRKRFP...QCKFSVRVPYYG-........RISFDIKSSPYE.KGs..vyL..................DAVLGYCNNl...lDAYKHTYSAAD---..............PYTDFAGV......-YNFTGWVEISWEY-k................................................................................................
A0A7L8V6N3_9PROT/3-118 ....yi--KTEQVKAIRDQIKKEFP...NVKFSVTREHYS-........SVKIVILSSEID.FF.....-..................ADYIKTIERye.aeRTYL----------..............--------......---------------qvnhhyidtsftglskevlskiseiahsqnwfdesdsmtdyfhtayyvgisigd...........................................
A0A7J0AYC8_9BACT/92-180 .....q-HAPEVVELIRRWLKETYP...RYKFSVRRPDCN-........SIHISLMQADFE.AF....tA..................ASGVKTYAD....iNHYHIDSET-----..............DLTDRARE.....vMQNVCAFVQSYN---fd...............................................................................................
A0A0U2X666_9ACTN/4-103 ......IDTKDVAAELRNRLKSAFP...GVKFSVRKGTGTAs......aWISVYWTDGPCS.AD.....V..................EELTRPMQG.....AQFNGMEDRYESTD.............nTVTVTVKGrk..vtGKPLVDGINTHRGVS.................................................................................................
A0A7W7KET0_9PSED/138-225 ..ydmn----GAAKNVRATLKQYFP...KVKFSVRRDSFT-........-LRVSWTDGPTA.KQ.....V..................DEILAPFKT.....GGFDPYQDMATSQD..............TPFSVVYG......---GFEYLFTSRET-s................................................................................................
G2GF06_9ACTN/96-187 .....i-PAKYAAVHLRKELRRVFP...GVKFSVRTGTGKRr......gEITVTWTGGPRR.TS.....V..................SAVAAPLM-.....ARFGPGDRRIA---..............RVDVTVGG......-RRYC----------gvpmvsaiklnr.....................................................................................
A0A0F5JT21_9BURK/7-100 .....l-SCADTAKLVRASLKEAFP...QCRFSVRSSTYAGg......aSISIRWTDGPNH.TQ.....V..................EFITGKFAG.....SYFDGSIDYKG---..............SIFHLLDGa....pVHMGADSIHLSRSYS.................................................................................................
A0A7W7KEU9_9PSED/134-221 ...ndp---KAATKNLRIELRRAYP...GIKFSVRSSSGS-........-TTIRWTDGPTG.DE.....V..................NALVGRYEI.....GRFDGMQDLATTEE.............tPFSKVFGG......----IKYLFTSRM--hs...............................................................................................
A0A3M9MH14_9MICO/15-103 ..ltpv----ETAKLIRRALRAAHP...HTRFHLVCSRGTGy......gYMSLQWVAGPST.AA.....V..................RTTVEPFLS.....EVASDEP-------..............--------......---------------ddavrrlpvpytckgidlirleke.........................................................................
A0A4R8XRM5_9MICO/5-105 ......ISTKDTAKLVRVALKNAFP...GVKFSVRMSTGTAs......aWMNVSWSDGPTD.RE.....V..................SAVTAIYEG.....RKFNGMTDGYDDQG..............SALVAFDGedmprvVRYSCDGINTHRDYT.................................................................................................
G9BW63_9CAUD/1-93 ......MNNQQIIHQAKLILRDTYR...HARFVVTVEGSD-........-IIVSWTDGPTE.KS.....V..................MGFISYLSAnikpnRTYTEQQEEA----..............--------......---------------diweflvnnsqiwefvvnddakah.........................................................................
A0A060R8M2_9BACT/336-424 ......YDQKVAANNLRVLLKRKFS...ETKFSVKKYYYD-........SYTVSWVDGPTV.GQ.....V..................TEITRLFRN.....EGFDGMTDSSYPII..............TPFNERYG......---GIGSISAERKVS.................................................................................................
A0A411YDS4_9ACTN/7-105 ...lap---TETAKLLRKHLRATFP...SAKFSVRTSKYAGg......aSLRVSWTDGPTD.DE.....V..................RAATSLYEG.....ADFDGMTDCKHYRD..............SILAHQDGtv..eaVHHGADFIFTHRQLS.................................................................................................
A0A0M8STW1_9ACTN/99-189 ..lplp----RTAAHLRTLLSARFP...GVRFSVRARRGW-........RLAVSWSGGPLD.TE.....V..................ATVAAPLLA.....DYATPGRRRAR---..............PVTVTRFGra..thGTPLVDAITLNR---r................................................................................................
A0A2V3PYH8_9BACT/83-180 .....l-RTKDIAKIVREYLKEKYP...TYKFSITAPDYN-........SLDIALLEAPQD.VI.....V..................YDNLDDCQK.....KYYNENTLNFD---..............--------......---------------vnyyhiskddrltelcreilqdafdfaqtynf.................................................................
C5ANP5_BURGB/32-128 ..ltlv----DTAQLVQKILGEAFP...SCAFAVSVHSTGAg......tLLDVAWTDGPRA.DQ.....V..................GRFVHPLQA.....RRLAHGGRAVAVEH.............fTLTPVGYR.....tVRLAADRISLTRAFS.................................................................................................
A0A502G2W7_9PROT/153-239 ....hs--GKLAAANIRVQLRQSFP...GVRFSVRNTDHG-........SIYVRWPGGPEQ.KA.....I..................ETVAMPFQG.....GHFDGMDDSYKTAR.............sAWCEAFGG......----AQYV-------vcrre............................................................................................
A0A368VL74_9BACL/8-98 ....ip--GKEAKKHILAALKLVFP...GFKFSLTSEYDS-........-VLVSWTDGPLT.PD.....V..................QKVLNRFES....yTRVLWKTDYTEPTG.............yEW------......---------------kgqlylgprylstvrrlsd..............................................................................
A0A415DSW7_9BACT/92-179 .....q-HAPEIVELTRIWLKETYP...RYRFSVRRENYN-........SIHVRLMKADFE.AF.....-..................TRESGKVQDe...iNHYCIESDE-----..............SLTDRAKE.....vMMNICDFVMSYN---fd...............................................................................................
A0A7G6Z5W8_9MICO/5-105 ......ISTKDTAKLVRGALKSAFP...GVKFSVRMSSGTAs......aWMRVQWDDGPTT.RE.....V..................DAITTRFEG.....RKFNSMTDGYDDAG..............TVLVAGQGdqmpreIRYSCDGINTQRDYT.................................................................................................
G2H045_9ENTR/119-211 ..eeel-----VICNLRIELQACFP...DVKFTVRKVLDS-........CVTVCWEDGVPD.DQ.....V..................GYIIGKYQN....gIIFGKCQNRII--Q.............cPFHDVFGG......----VSYVVHDRH--ysdafvqy.........................................................................................
V8CVB7_9NOCA/4-104 ......FTTKETAAELRKHLRATWP...TVKFSVRCGRGTAs......aWLRVAWVDGPAY.TQ.....A..................QSEWVQFQS.....AQFNGMTDSYDQLD.............dRLVCTDPAel.pevRSYSCDGINGERAF-t................................................................................................
D7V1G9_LISGR/58-149 ..dpsi-----TAKKVKGALQSAFPdlpKKHFSVQVNRLG-........DIDVKWVDYPAK.KT.....V..................EEITKGYQS.....ATYDKELET-DIVH..............GYEENGQR......-IQGAGYI-------tlsgtls..........................................................................................
A0A4P8J444_9BURK/6-99 .....l-SCAETAKLVRQALKEAFP...GVKFGVRSSTYSGg......aSISVRWEDGPNT.AQ.....V..................EAITNRFKG.....AYFDGSIDYKG---..............SVYHMMDGq....qISFGADYIFTSRSYT.................................................................................................
T0IXT1_9SPHN/131-219 .....a-SGKLAAQNIRAELKAAFP...GIRFGVRKAHWG-........SVSVTWTDGPTE.KR.....V..................GEIVNKYQG.....GHFNGMDDIYERAD.............sPWTSVFGG......----SKYVFTSREFS.................................................................................................
A0A396MSZ0_9BACT/93-181 ...qrp---SEVADLFRKWVKETYP...GYKFSVRVRNYD-........SITIQLLVADFA.PF.....-..................TESSGITCN.....CSVNHYYIERD--D..............DLTDRAKE.....vMQNVTDYIMSYN---yd...............................................................................................
A0A4V6QHF0_9MICO/5-105 ......ISTKDTAKLVRVALKNAFP...GVKFSVRMSTGTAs......aWMNVSWSDGPTD.RE.....V..................SAVTSQYEG.....RKFNGMTDGYDEQG..............SALVAFDGedmprvVRYSCDGINTHRDYT.................................................................................................
F8XMH6_9PROT/1-77 ......------------MLKRAFP...TVKFSVKKSSHS-........TVDVSWTDGPIT.SQ.....V..................EQYTRQFEA.....GRFNGMEDIYDYKR.............tPWNTLFGA......----IDMILVHRNT-s................................................................................................
A0A0Q5N9X1_9MICO/5-105 .....i-PTKDVAKLLRTELRAAFP...GVKFTVRCSTGTAs......aWMNVSWADGPTT.GQ.....V..................DEIAGRFEG.....RKFNGMTDSYDHQG..............SVLIAGQGaampeeVVYGCDGILTARTFT.................................................................................................
A0A0N1CVM6_9MICO/1-81 ......-------------------...-MKFSVRCSTGTAs......aWMNVAWADGPTT.RQ.....V..................GDITGRFEG.....RKFNGITDSYDHQG..............SVLVAGEGeampeeVVYGCDGINTARTYS.................................................................................................
A0A6N9Q0D5_9BACL/2-98 .....s-DCVQVAKQIRKELKEVFP...YTKFSVRSSKYSMg......sSITISWNNMPLN.KE.....V..................KEVTDKYAE....iSYCEASGE------..............--------......---------------ilsggnmyvstsynitnefreecekeitee...................................................................
A0A1C5FKN5_9ACTN/99-194 .....v-STRVTAIHLRRMLRAAFP...GVKFSVRCGRRDAkgl..tpfEITVTWAGGPTR.TA.....V..................ATVTSPLL-.....ATYGTAEERRAR--..............RISVTTDG......-RT------------hngfpsvyaihlr....................................................................................
A0A0V7ZCI7_9CYAN/5-96 ......ISAKEVAKHIRKDLKTKFP...SIKFSVRSETGT-........-IRISYTDGVPA.EE.....I..................KEICTKYDS....rRDYDPQYCDYRKSE..............PVEINGEM......LTTSVDYFFIDRNLS.................................................................................................
C5A9B2_BURGB/4-106 .....i-SRRETLSLVRKALHEAFP...QTTFTLQPSRSKGnaa.cgftLVWVKWIDGPSS.SQ.....V..................HDVVSRFED.....RI------------..............--------......---------------idwdrptpwsnqpkanhlldghavrfdvsffslkrtms...........................................................
A0A328EJF5_9BACT/3-92 skrqtp------AMLIKKDLKKVFP...GVKFSCKYDSFSGg......dSVRIYWKGGPLT.RA.....V..................NKIAIQYKD.....GYFDSMEDIYH---..............HINDKPYG......--MTAKYIICN----rend.............................................................................................
#=GC seq_cons ........st-sAphlRphLKcsFP...ssKFSVRpsphs.........plplsWs-GPtp.tt.....V..................pphssthps.....spasthpctht.................shh.hh.t..........hphl...p....................................................................................................
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