GenomeNet

Database: Pfam
Entry: Na_Pi_cotrans
LinkDB: Na_Pi_cotrans
Original site: Na_Pi_cotrans 
#=GF ID   Na_Pi_cotrans
#=GF AC   PF02690.18
#=GF DE   Na+/Pi-cotransporter
#=GF AU   Bashton M;0000-0002-6847-1525
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF AU   Haft D;0000-0001-8101-4938
#=GF SE   Pfam-B_509 (release 5.5)
#=GF GA   29.10 29.10;
#=GF TC   29.20 29.10;
#=GF NC   28.70 29.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   9826740
#=GF RT   Characterization of a murine type II sodium-phosphate
#=GF RT   cotransporter expressed in mammalian small intestine. 
#=GF RA   Hilfiker H, Hattenhauer O, Traebert M, Forster I, Murer H, Biber
#=GF RA   J; 
#=GF RL   Proc Natl Acad Sci U S A 1998;95:14564-14569.
#=GF DR   INTERPRO; IPR003841;
#=GF DR   TC; 2.A.58;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This is a family of mainly mammalian type II renal
#=GF CC   Na+/Pi-cotransporters with other related sequences from lower
#=GF CC   eukaryotes and bacteria some of  which are also
#=GF CC   Na+/Pi-cotransporters.  In the kidney the type II renal 
#=GF CC   Na+/Pi-cotransporters protein allows re-absorption of filtered
#=GF CC   Pi in the  proximal tubule [1].
#=GF SQ   11434
#=GS C0QHS1_DESAH/161-282        AC C0QHS1.1
#=GS C4KZ12_EXISA/12-151         AC C4KZ12.1
#=GS A0A559J359_9BACL/15-167     AC A0A559J359.1
#=GS A0A396LDA1_9FIRM/25-161     AC A0A396LDA1.1
#=GS A0A6P8FUQ9_CLUHA/74-208     AC A0A6P8FUQ9.1
#=GS A0A672LXR6_SINGR/183-327    AC A0A672LXR6.1
#=GS A0A3D9Z361_9RHIZ/158-302    AC A0A3D9Z361.1
#=GS F7NSD5_9GAMM/15-156         AC F7NSD5.1
#=GS A0A1Y4B3P2_9FIRM/144-294    AC A0A1Y4B3P2.1
#=GS A0A1M6MA24_9FIRM/149-278    AC A0A1M6MA24.1
#=GS A0A3Q1F726_9TELE/83-215     AC A0A3Q1F726.1
#=GS F7HDA3_MACMU/110-247        AC F7HDA3.3
#=GS YJBB_SALTY/150-265          AC P40730.2
#=GS A0A1E4QQ58_9BURK/153-289    AC A0A1E4QQ58.1
#=GS A0A233HLH6_9VIBR/215-339    AC A0A233HLH6.1
#=GS A0A371IIW2_9FIRM/1-96       AC A0A371IIW2.1
#=GS K6XFD5_9ALTE/165-302        AC K6XFD5.1
#=GS A0A2W7MTT1_9BACI/18-154     AC A0A2W7MTT1.1
#=GS A0A140KZC5_9CLOT/15-151     AC A0A140KZC5.1
#=GS A0A4Y8V4G9_9GAMM/40-227     AC A0A4Y8V4G9.1
#=GS A0A1U7NL90_9FIRM/169-294    AC A0A1U7NL90.1
#=GS A0A5D8Q8T0_9THEO/146-293    AC A0A5D8Q8T0.1
#=GS A0A1I1IZG1_9BACT/217-370    AC A0A1I1IZG1.1
#=GS A0A671WS51_SPAAU/49-184     AC A0A671WS51.1
#=GS E1T5X2_BURSG/13-149         AC E1T5X2.1
#=GS A0A1H6RHV4_9FIRM/15-151     AC A0A1H6RHV4.1
#=GS R7NQT3_9FIRM/19-155         AC R7NQT3.1
#=GS A0A6P1ZDY2_9DELT/15-156     AC A0A6P1ZDY2.1
#=GS U2P6J0_9BACT/15-152         AC U2P6J0.1
#=GS A0A4W6EA95_LATCA/303-439    AC A0A4W6EA95.1
#=GS A0A4W5R6M6_9TELE/292-438    AC A0A4W5R6M6.1
#=GS A0A374CIH3_9BACT/173-281    AC A0A374CIH3.1
#=GS A0A6A3UES5_9STRA/279-460    AC A0A6A3UES5.1
#=GS A0A0M1UXA5_PAESO/13-151     AC A0A0M1UXA5.1
#=GS A0A091RMG7_NESNO/109-248    AC A0A091RMG7.1
#=GS A4J846_DESRM/16-152         AC A4J846.1
#=GS A0A1B9QYR8_9VIBR/216-340    AC A0A1B9QYR8.1
#=GS A0A1Y5SBS1_9PROT/177-294    AC A0A1Y5SBS1.1
#=GS H0WU56_OTOGA/110-246        AC H0WU56.1
#=GS A0A672ILV2_SALFA/84-217     AC A0A672ILV2.1
#=GS A0A2T0BI39_9CLOT/17-153     AC A0A2T0BI39.1
#=GS A8IDX7_AZOC5/13-151         AC A8IDX7.1
#=GS E8TC82_MESCW/16-152         AC E8TC82.1
#=GS A0A3A9E4T9_9FIRM/15-164     AC A0A3A9E4T9.1
#=GS A4A5U2_9GAMM/33-178         AC A4A5U2.2
#=GS A0A368YLJ4_9FIRM/156-283    AC A0A368YLJ4.1
#=GS A0A2S3QP43_9PROT/16-150     AC A0A2S3QP43.1
#=GS A0A4R3KJY3_9BACI/142-284    AC A0A4R3KJY3.1
#=GS A0A399SY83_9BACT/158-290    AC A0A399SY83.1
#=GS A0A498G8F8_9EURY/24-172     AC A0A498G8F8.1
#=GS Q3IX36_RHOS4/19-155         AC Q3IX36.1
#=GS A0A3M7RR05_BRAPC/22-161     AC A0A3M7RR05.1
#=GS A0A1Y4TLJ2_9FIRM/15-164     AC A0A1Y4TLJ2.1
#=GS A0A068YP01_9BURK/13-149     AC A0A068YP01.1
#=GS D3SBJ3_THISK/22-163         AC D3SBJ3.1
#=GS A0A1Q9DDG0_SYMMI/70-132     AC A0A1Q9DDG0.1
#=GS A0A3M7TT83_9BACI/14-149     AC A0A3M7TT83.1
#=GS A0A516KGU8_9BACI/18-154     AC A0A516KGU8.1
#=GS A0A1H3KPJ2_9BACI/145-311    AC A0A1H3KPJ2.1
#=GS A0A1L3GIY1_PELAE/19-155     AC A0A1L3GIY1.1
#=GS V9W9H5_9BACL/182-311        AC V9W9H5.1
#=GS A0A1X4IT70_9RHOB/16-152     AC A0A1X4IT70.1
#=GS G3NAB5_GASAC/306-506        AC G3NAB5.1
#=GS A0A3Q9HP46_9FIRM/14-153     AC A0A3Q9HP46.1
#=GS A0A380LKN2_9FIRM/144-293    AC A0A380LKN2.1
#=GS I3MK46_ICTTR/109-246        AC I3MK46.2
#=GS A3YYI2_9SYNE/168-313        AC A3YYI2.1
#=GS Q0W3W9_METAR/15-149         AC Q0W3W9.1
#=GS A0A2N5X4C8_9GAMM/16-150     AC A0A2N5X4C8.1
#=GS D6XW71_BACIE/147-313        AC D6XW71.1
#=GS A0A1X7PIJ6_9RHIZ/16-152     AC A0A1X7PIJ6.1
#=GS F6VIB1_ORNAN/108-249        AC F6VIB1.2
#=GS R7B5A9_9CLOT/169-301        AC R7B5A9.1
#=GS A0A6P7I440_9TELE/336-491    AC A0A6P7I440.1
#=GS A0A1H0QEJ9_9BURK/146-297    AC A0A1H0QEJ9.1
#=GS B5JGI5_9BACT/19-155         AC B5JGI5.1
#=GS W4F575_9BACL/163-279        AC W4F575.1
#=GS S2Y7X7_9BACL/18-154         AC S2Y7X7.1
#=GS A0A2G1UHE5_9ALTE/15-156     AC A0A2G1UHE5.1
#=GS A0A556A8B2_9BURK/13-151     AC A0A556A8B2.1
#=GS A0A0J1F7A0_9FIRM/153-293    AC A0A0J1F7A0.1
#=GS A0A1Y4M1L9_9FIRM/15-164     AC A0A1Y4M1L9.1
#=GS F9D2R7_PREDD/175-283        AC F9D2R7.1
#=GS A0A108T970_BACSE/167-327    AC A0A108T970.1
#=GS A0A2S0MXM4_9BURK/13-149     AC A0A2S0MXM4.1
#=GS A0A640PZB7_9FLAO/16-157     AC A0A640PZB7.1
#=GS A0A2I0TN74_LIMLA/122-260    AC A0A2I0TN74.1
#=GS A0A4R1PWJ9_9FIRM/144-271    AC A0A4R1PWJ9.1
#=GS A0A4U5V8R9_COLLU/29-169     AC A0A4U5V8R9.1
#=GS A0A1G9WLX7_9BACI/27-163     AC A0A1G9WLX7.1
#=GS A0A1H2S846_9PSED/147-290    AC A0A1H2S846.1
#=GS T0RQI7_9PROT/167-297        AC T0RQI7.1
#=GS A0A2H2ICI3_CAEJA/165-303    AC A0A2H2ICI3.1
#=GS A0A1R4GWI7_9GAMM/1-116      AC A0A1R4GWI7.1
#=GS G4QE87_GLANF/143-269        AC G4QE87.1
#=GS A0A2K6EFT2_PROCO/113-255    AC A0A2K6EFT2.1
#=GS M1WNA0_PSEP2/170-299        AC M1WNA0.1
#=GS A0A2I4CNP9_9TELE/278-467    AC A0A2I4CNP9.1
#=GS B7CDQ8_9FIRM/24-160         AC B7CDQ8.1
#=GS H0WH42_OTOGA/396-551        AC H0WH42.1
#=GS A0A085EY54_9BRAD/153-273    AC A0A085EY54.1
#=GS A0A1I5XU89_9LACT/143-277    AC A0A1I5XU89.1
#=GS R5VHQ0_9CLOT/158-292        AC R5VHQ0.1
#=GS A0A1G5RXM2_9FIRM/15-151     AC A0A1G5RXM2.1
#=GS A0A139XGB0_9CYAN/100-236    AC A0A139XGB0.1
#=GS A0A1S8DGS9_9PSED/217-342    AC A0A1S8DGS9.1
#=GS A0A1Y2K1I5_9PROT/33-173     AC A0A1Y2K1I5.1
#=GS A0A1N7KR40_9RHOB/13-153     AC A0A1N7KR40.1
#=GS D3FW79_ALKPO/146-310        AC D3FW79.1
#=GS K6VLS7_9MICO/60-222         AC K6VLS7.1
#=GS A0A1H9RDB4_9BACI/14-149     AC A0A1H9RDB4.1
#=GS A0A4S5J6E7_9RHIZ/183-293    AC A0A4S5J6E7.1
#=GS A0A101K0P3_9BRAD/143-295    AC A0A101K0P3.1
#=GS A0A0X3UEF6_9RHOB/20-156     AC A0A0X3UEF6.1
#=GS A0A3N5AP06_9THEO/92-238     AC A0A3N5AP06.1
#=GS A0A133YNA4_9FIRM/142-268    AC A0A133YNA4.1
#=GS A4ESC9_9RHOB/16-151         AC A4ESC9.1
#=GS R0AG52_9FIRM/15-151         AC R0AG52.1
#=GS A0A1H2ZY95_9FIRM/140-268    AC A0A1H2ZY95.1
#=GS A0A2A2SIK7_9SPHN/151-307    AC A0A2A2SIK7.1
#=GS S6GJH4_9GAMM/154-289        AC S6GJH4.1
#=GS R5R5T0_9FIRM/15-164         AC R5R5T0.1
#=GS A0A3E2NEQ7_9CLOT/18-164     AC A0A3E2NEQ7.1
#=GS A0A0D6T0G5_9PSED/152-287    AC A0A0D6T0G5.1
#=GS A0A4P6K609_9CHLR/20-156     AC A0A4P6K609.1
#=GS R7EXE7_9BACT/166-287        AC R7EXE7.1
#=GS A0A3E0WHJ8_9GAMM/15-156     AC A0A3E0WHJ8.1
#=GS A0A014NAP3_9GAMM/13-149     AC A0A014NAP3.1
#=GS W8KT14_9GAMM/201-305        AC W8KT14.1
#=GS A0A410JWA9_9BACT/19-155     AC A0A410JWA9.1
#=GS A0A1H1HDN6_9RHIZ/16-152     AC A0A1H1HDN6.1
#=GS A0A091SSA8_PELCR/21-211     AC A0A091SSA8.1
#=GS A0A2D3WTC6_9PROT/170-305    AC A0A2D3WTC6.1
#=GS A0A0Q4BA21_9BACT/174-285    AC A0A0Q4BA21.1
#=GS A0A1I2KP56_9BACL/196-307    AC A0A1I2KP56.1
#=GS R5P1A1_9BACT/17-158         AC R5P1A1.1
#=GS A0A2S8SAK2_9RHOB/160-299    AC A0A2S8SAK2.1
#=GS V4AJ82_LOTGI/339-535        AC V4AJ82.1
#=GS B7PLN4_IXOSC/318-527        AC B7PLN4.1
#=GS A0A0F0C7X8_9CLOT/15-151     AC A0A0F0C7X8.1
#=GS A0A2N6RNU9_9BACI/19-155     AC A0A2N6RNU9.1
#=GS K0AZG4_GOTA9/142-269        AC K0AZG4.1
#=GS A0A672LPX7_SINGR/56-192     AC A0A672LPX7.1
#=GS A0A6P7YQF7_9AMPH/287-489    AC A0A6P7YQF7.1
#=GS A0A341BEX0_NEOAA/113-251    AC A0A341BEX0.1
#=GS A0A6I6DJG3_9FIRM/18-154     AC A0A6I6DJG3.1
#=GS C7DB37_9RHOB/19-155         AC C7DB37.1
#=GS A0A1M5W9N1_9CLOT/16-152     AC A0A1M5W9N1.1
#=GS A0A3L7K5H0_9BACI/13-147     AC A0A3L7K5H0.1
#=GS A0A2Z2NQ96_9GAMM/142-296    AC A0A2Z2NQ96.1
#=GS A0A074LV20_9BACL/16-150     AC A0A074LV20.1
#=GS A0A369Y476_9FUSO/17-153     AC A0A369Y476.1
#=GS A0A0K9IB87_9DELT/145-282    AC A0A0K9IB87.1
#=GS E0NSX7_9BACT/168-282        AC E0NSX7.1
#=GS A0A1S3EIY5_DIPOR/285-487    AC A0A1S3EIY5.1
#=GS A0A391NXA7_9EUKA/23-79      AC A0A391NXA7.1
#=GS W0EPB5_9BACT/17-157         AC W0EPB5.1
#=GS A0A4W4FRH5_ELEEL/169-310    AC A0A4W4FRH5.1
#=GS A0A1Z4RP52_9CHRO/93-229     AC A0A1Z4RP52.1
#=GS A0A4R3M8K9_9RHIZ/13-151     AC A0A4R3M8K9.1
#=GS F7JPK1_9FIRM/152-273        AC F7JPK1.1
#=GS A0A1T4R5I8_9GAMM/33-173     AC A0A1T4R5I8.1
#=GS A0A2S0UC63_9BACL/15-167     AC A0A2S0UC63.1
#=GS A4Y025_PSEMY/37-176         AC A4Y025.1
#=GS A0A0A5G710_9BACI/14-149     AC A0A0A5G710.1
#=GS A0A6F8PRN7_9GAMM/195-319    AC A0A6F8PRN7.1
#=GS H3GU40_PHYRM/270-457        AC H3GU40.1
#=GS G9YSS0_FLAPL/151-283        AC G9YSS0.1
#=GS A0A0M1UXA5_PAESO/145-271    AC A0A0M1UXA5.1
#=GS A0A1V2MGE2_9FIRM/158-319    AC A0A1V2MGE2.1
#=GS K9TBR9_9CYAN/30-176         AC K9TBR9.1
#=GS A0A448ZHC3_9STRA/59-195     AC A0A448ZHC3.1
#=GS A0A1S3WCZ8_ERIEU/113-252    AC A0A1S3WCZ8.1
#=GS U1FLK4_TRESO/199-328        AC U1FLK4.1
#=GS A0A1G8B3G5_9VIBR/28-223     AC A0A1G8B3G5.1
#=GS A0A2T7NHU9_POMCA/9-139      AC A0A2T7NHU9.1
#=GS A0A3D9LH86_9BACT/198-373    AC A0A3D9LH86.1
#=GS R7RRL6_9CLOT/144-287        AC R7RRL6.1
#=GS A0A3A9K247_9BACI/15-147     AC A0A3A9K247.1
#=GS A0A1I0WJU0_9FIRM/15-164     AC A0A1I0WJU0.1
#=GS A0A1H4FHB9_9BURK/139-288    AC A0A1H4FHB9.1
#=GS A0A671EEQ6_RHIFE/344-468    AC A0A671EEQ6.1
#=GS R5Y2G5_9CLOT/147-268        AC R5Y2G5.1
#=GS A0A443RMD3_9ACAR/104-246    AC A0A443RMD3.1
#=GS R5HIG1_9FIRM/15-164         AC R5HIG1.1
#=GS A0A1I7JIG1_9FIRM/20-170     AC A0A1I7JIG1.1
#=GS A0A4U6CGG0_9RHIZ/10-146     AC A0A4U6CGG0.1
#=GS A0A4R3NBZ4_9BACI/18-154     AC A0A4R3NBZ4.1
#=GS A0A3Q1EFB8_9TELE/81-213     AC A0A3Q1EFB8.1
#=GS A0A6P6QRG9_CARAU/360-561    AC A0A6P6QRG9.1
#=GS Q8XHV8_CLOPE/17-153         AC Q8XHV8.1
#=GS E6K5J2_9BACT/18-155         AC E6K5J2.1
#=GS A0A3S4S639_9BACI/144-277    AC A0A3S4S639.1
#=GS A0A1M5FHA6_9BACT/165-284    AC A0A1M5FHA6.1
#=GS A0A1U8CTC7_MESAU/337-534    AC A0A1U8CTC7.1
#=GS A0A1H9S935_9BACI/18-154     AC A0A1H9S935.1
#=GS G3IB01_CRIGR/109-246        AC G3IB01.1
#=GS D1PSD9_9FIRM/21-169         AC D1PSD9.1
#=GS D4MWG9_ANAHA/19-162         AC D4MWG9.1
#=GS A0A0G4EJJ2_VITBC/63-207     AC A0A0G4EJJ2.1
#=GS A0A6I1FNB8_9BACI/146-318    AC A0A6I1FNB8.1
#=GS A0A2K6F4G0_PROCO/335-479    AC A0A2K6F4G0.1
#=GS A0A095ZND7_9FIRM/15-164     AC A0A095ZND7.1
#=GS E1X319_HALMS/16-151         AC E1X319.1
#=GS F4GE92_ALIDK/13-149         AC F4GE92.1
#=GS F2BGA9_9NEIS/195-322        AC F2BGA9.1
#=GS A0A1M5C873_9BACE/17-157     AC A0A1M5C873.1
#=GS A0A5C6MTS4_9TELE/416-522    AC A0A5C6MTS4.1
#=GS A0A671WEB1_SPAAU/347-532    AC A0A671WEB1.1
#=GS M5UEG7_9BACT/150-298        AC M5UEG7.1
#=GS A0A1V1I115_9FIRM/152-271    AC A0A1V1I115.1
#=GS A0A1M4W2S3_9THEO/145-293    AC A0A1M4W2S3.1
#=GS A0A3M7SLB1_BRAPC/377-548    AC A0A3M7SLB1.1
#=GS A0A6P6HVP5_PUMCO/361-552    AC A0A6P6HVP5.1
#=GS A0A1V4CK32_9BURK/172-302    AC A0A1V4CK32.1
#=GS A0A1H8DCD3_9BACT/16-156     AC A0A1H8DCD3.1
#=GS A0A1I4MKJ3_9BURK/13-153     AC A0A1I4MKJ3.1
#=GS A0A157SHI4_9BORD/156-296    AC A0A157SHI4.1
#=GS A0A5B8ZAP6_9BACI/13-147     AC A0A5B8ZAP6.1
#=GS A0A384D739_URSMA/85-186     AC A0A384D739.1
#=GS A0A6P9CSC8_PANGU/118-257    AC A0A6P9CSC8.1
#=GS A0A1H0L1F2_9PSED/150-289    AC A0A1H0L1F2.1
#=GS A8ZVJ8_DESOH/59-195         AC A8ZVJ8.1
#=GS G2TNK2_BACCO/13-148         AC G2TNK2.1
#=GS A0A5E4NTD0_9RHIZ/18-152     AC A0A5E4NTD0.1
#=GS A0A1R3VMR2_9GAMM/33-173     AC A0A1R3VMR2.1
#=GS K4R5R0_STRDJ/184-345        AC K4R5R0.1
#=GS A0A1M6ZH96_9RHOB/33-173     AC A0A1M6ZH96.1
#=GS G4L1F0_OSCVS/143-271        AC G4L1F0.1
#=GS C3YCZ4_BRAFL/86-230         AC C3YCZ4.1
#=GS W8KWA8_9GAMM/12-219         AC W8KWA8.1
#=GS A0A672STF0_SINGR/335-513    AC A0A672STF0.1
#=GS A0A1I0A468_9BACI/17-153     AC A0A1I0A468.1
#=GS A0A667WYM9_9TELE/352-554    AC A0A667WYM9.1
#=GS A6CNW2_9BACI/21-157         AC A6CNW2.1
#=GS A0A225V9B4_9STRA/279-471    AC A0A225V9B4.1
#=GS A0A3Q9B746_9FIRM/10-148     AC A0A3Q9B746.1
#=GS D4IWI4_BUTFI/145-294        AC D4IWI4.1
#=GS R5M098_9FIRM/166-303        AC R5M098.1
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D3SBJ3_THISK/22-163                    ..............................................................LFLL.G.MTL.L.TD.G.LKTAG...G..K.A..L..Q..H.I..L....GQ..W.T.R..TR............PHA....L....A....SG.M....GVT...A.LVQSSSAV....T.VA..T..IGF..A..............N.......A........G...............L.........L........T.......L....G.........QSV.....WVI....FGS..NVGTTMT.G.WLVal............................................................igfNIR...I..E....A...F.A.L....P..A...I..G.I...GAL............LYLFM.................KAA............RPRYLG.....L.A.LA..........G.F...GL.L.FF.GIDVLR-e......................................................................................................
A0A1Q9DDG0_SYMMI/70-132                ..............................................................MFLM.G.LDM.M.GS.S.FLVLG...G..K.G..A..G..D.L..F....-T..I.V.D..NP............VTG....L....M....VG.I....IAT...V.LVQSSSTS....T.SI..V..AA-..-..............-.......-........-...............-.........-........-.......-....-.........---.....---....---..-------.-.---.................................................................---...-..-....-...-.-.-....-..-...-..-.-...---............-----.................---............------.....-.-.--..........-.-...--.-.--.-------cllgfy.................................................................................................
A0A3M7TT83_9BACI/14-149                ..............................................................LFLF.G.MTV.M.RQ.G.LFNLQ...R..R.R..M..S..E.L..L....IS..F.I.D..KP............YKG....L....I....IG.T....VVT...G.LLQSSSAV....M.IM..T..VGL..V..............A.......T........R...............V.........I........S.......F....R.........HSI.....GIM....LGA..NIGTCLT.L.EIV.................................................................ALD...I..N....W...L.I.I....P..L...L..I.I...GLP............LLMT-.................KNQ............VLFCLG.....C.F.SF..........G.L...GS.I.FV.AMHGF--et..............................................................................................