#=GF ID PDDEXK_9
#=GF AC PF08011.17
#=GF DE PD-(D/E)XK nuclease superfamily
#=GF PI DUF1703;
#=GF AU Mistry J;0000-0003-2479-5322
#=GF SE Pfam-B_5377 (release 16.0)
#=GF GA 25.50 25.50;
#=GF TC 25.50 25.50;
#=GF NC 25.40 25.40;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -E 1000 -Z 81514348 HMM pfamseq
#=GF TP Family
#=GF CL CL0236
#=GF RN [1]
#=GF RM 17584917
#=GF RT Realm of PD-(D/E)XK nuclease superfamily revisited: detection of
#=GF RT novel families with modified transitive meta profile searches.
#=GF RA Knizewski L, Kinch LN, Grishin NV, Rychlewski L, Ginalski K;
#=GF RL BMC Struct Biol. 2007;7:40.
#=GF DR INTERPRO; IPR012547;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This family contains many hypothetical bacterial proteins. It
#=GF CC has been identified as a member of the PD-(D/E)XK nuclease
#=GF CC superfamily through transitive meta profile searches [1].
#=GF CC DUF1703 has the predicted secondary structure pattern of the
#=GF CC restriction endonuclease-like fold core and contains an
#=GF CC additional beta-strand at the C-terminus [1].
#=GF SQ 2800
#=GS A0A0M9E4C8_9BACT/465-578 AC A0A0M9E4C8.1
#=GS A9G341_SORC5/456-560 AC A9G341.1
#=GS A0A8H3WWY3_GIGMA/644-752 AC A0A8H3WWY3.1
#=GS A0A1I5XQT3_9FIRM/472-576 AC A0A1I5XQT3.1
#=GS W4LQF4_ENTF1/456-572 AC W4LQF4.1
#=GS A0A417CGZ5_9FIRM/420-517 AC A0A417CGZ5.1
#=GS R5HN80_9FIRM/513-618 AC R5HN80.1
#=GS E4TFT2_CALNY/413-505 AC E4TFT2.1
#=GS R6EA76_9BACT/420-512 AC R6EA76.1
#=GS A0A165ZDG8_9EURY/427-522 AC A0A165ZDG8.1
#=GS R6L9Z5_9FIRM/426-529 AC R6L9Z5.1
#=GS R7JCR4_9BACT/427-519 AC R7JCR4.1
#=GS A0A7U7GBD1_9GAMM/400-492 AC A0A7U7GBD1.1
#=GS A0A3A9EP22_UNCXX/422-521 AC A0A3A9EP22.1
#=GS A0A1Y3TGI6_9FIRM/547-649 AC A0A1Y3TGI6.1
#=GS A0A075APT3_ROZAC/460-563 AC A0A075APT3.1
#=GS A0A143X1T1_9FIRM/441-547 AC A0A143X1T1.1
#=GS A0A7Y3TX21_9GAMM/420-514 AC A0A7Y3TX21.1
#=GS R6X9E8_9BACT/334-427 AC R6X9E8.1
#=GS A0A412I5V4_9FIRM/418-512 AC A0A412I5V4.1
#=GS A0A510JKH9_9FUSO/450-545 AC A0A510JKH9.1
#=GS A0A5Q0EJT7_9GAMM/420-520 AC A0A5Q0EJT7.1
#=GS A0A562S830_9BACT/418-512 AC A0A562S830.1
#=GS A0A264Y6P9_9BACT/423-515 AC A0A264Y6P9.1
#=GS B1Y479_LEPCP/425-519 AC B1Y479.1
#=GS A0A662ZIA9_9GAMM/144-252 AC A0A662ZIA9.1
#=GS R7R3L6_9FIRM/455-556 AC R7R3L6.1
#=GS A0A1Y4NVH2_9FIRM/5-93 AC A0A1Y4NVH2.1
#=GS N2AM80_9FIRM/453-562 AC N2AM80.1
#=GS A0A377GVJ8_9FUSO/1-81 AC A0A377GVJ8.1
#=GS N9WL66_CLOIN/1-89 AC N9WL66.1
#=GS A0A1W1HGJ2_9BACT/142-234 AC A0A1W1HGJ2.1
#=GS A0A0N0V1K4_9BACT/31-157 AC A0A0N0V1K4.1
#=GS C4IGF3_CLOBU/137-217 AC C4IGF3.1
#=GS R6FBA4_9BACE/93-185 AC R6FBA4.1
#=GS D3PB81_DEFDS/413-505 AC D3PB81.1
#=GS A0A414BRN2_9BACT/423-517 AC A0A414BRN2.1
#=GS A0A1H1W5Q5_9PSED/415-509 AC A0A1H1W5Q5.1
#=GS A0A0R3K393_CALMK/449-556 AC A0A0R3K393.1
#=GS A0A4R3ZB46_9FIRM/300-396 AC A0A4R3ZB46.1
#=GS A0A1Y4AUD9_9BACE/426-518 AC A0A1Y4AUD9.1
#=GS E8LJY7_SUCHY/1-87 AC E8LJY7.1
#=GS R9KMG7_9FIRM/310-412 AC R9KMG7.1
#=GS A0A2Z6E059_HYDTE/33-130 AC A0A2Z6E059.1
#=GS A0A426DBE4_9FIRM/455-556 AC A0A426DBE4.1
#=GS I5AQV0_EUBCE/454-564 AC I5AQV0.1
#=GS A0A8J6QPR5_9BACT/1-45 AC A0A8J6QPR5.1
#=GS A0A7G1G5X4_9BACT/418-507 AC A0A7G1G5X4.1
#=GS A0A4S4LBX1_9AGAM/18-128 AC A0A4S4LBX1.1
#=GS A0A3A8WL78_UNCXX/452-561 AC A0A3A8WL78.1
#=GS A0A1V2YFV6_9FIRM/416-512 AC A0A1V2YFV6.1
#=GS A0A1Y4CF65_9FIRM/448-553 AC A0A1Y4CF65.1
#=GS A0A416JN45_9FIRM/22-125 AC A0A416JN45.1
#=GS A0A414BI99_9BACT/424-516 AC A0A414BI99.1
#=GS A0A1Y3N1J2_PIRSE/431-524 AC A0A1Y3N1J2.1
#=GS A0A255SQ23_9BACT/430-522 AC A0A255SQ23.1
#=GS W8KXJ3_9GAMM/422-516 AC W8KXJ3.1
#=GS R5EIY8_9GAMM/476-582 AC R5EIY8.1
#=GS A0A3G9J9K7_9FIRM/452-546 AC A0A3G9J9K7.1
#=GS W8KHH7_9GAMM/246-340 AC W8KHH7.1
#=GS A0A5M8FIG9_9GAMM/1-55 AC A0A5M8FIG9.1
#=GS A0A3A9GD14_9FIRM/417-514 AC A0A3A9GD14.1
#=GS C6LKU7_9FIRM/473-572 AC C6LKU7.1
#=GS A0A8H4EVQ4_GIGMA/328-444 AC A0A8H4EVQ4.1
#=GS A0A3E3I8J1_9FIRM/458-561 AC A0A3E3I8J1.1
#=GS A0A1I1LTD3_9CLOT/452-559 AC A0A1I1LTD3.1
#=GS Q8RHH4_FUSNN/113-218 AC Q8RHH4.1
#=GS R9JWV2_9FIRM/455-556 AC R9JWV2.1
#=GS S5ZQ79_9SPIR/436-528 AC S5ZQ79.1
#=GS R5S5B9_9CLOT/256-367 AC R5S5B9.1
#=GS A0A264Y4W9_9BACT/423-517 AC A0A264Y4W9.1
#=GS A0A8X6KDX5_NEPPI/486-595 AC A0A8X6KDX5.1
#=GS A0A2K4ZH35_9FIRM/418-516 AC A0A2K4ZH35.1
#=GS A0A317CGF8_9GAMM/454-560 AC A0A317CGF8.1
#=GS R6B3B5_9BACT/423-517 AC R6B3B5.1
#=GS A0A1V1NX72_9BACT/189-253 AC A0A1V1NX72.1
#=GS Q2FUP1_METHJ/417-513 AC Q2FUP1.1
#=GS A0A4Q7DG56_9RICK/194-299 AC A0A4Q7DG56.1
#=GS A0A1Y4HBY0_9BACT/424-516 AC A0A1Y4HBY0.1
#=GS A0A6M0L1J4_9BACT/412-501 AC A0A6M0L1J4.1
#=GS A0A7X3MF47_9FIRM/456-565 AC A0A7X3MF47.1
#=GS A0A7G1G677_9BACT/416-505 AC A0A7G1G677.1
#=GS A0A255T230_9BACT/440-538 AC A0A255T230.1
#=GS A0A2X0WXL0_9GAMM/483-590 AC A0A2X0WXL0.1
#=GS R9HP59_BACUN/424-516 AC R9HP59.1
#=GS A0A8H4ASB6_GIGMA/503-611 AC A0A8H4ASB6.1
#=GS R9MC54_9FIRM/479-579 AC R9MC54.1
#=GS A0A2M9A9Z0_9BACT/421-522 AC A0A2M9A9Z0.1
#=GS R6B5Q5_9FIRM/22-101 AC R6B5Q5.1
#=GS A0A1I1JLF5_9FIRM/8-76 AC A0A1I1JLF5.1
#=GS A0A0F0CPG3_9BACT/8-91 AC A0A0F0CPG3.1
#=GS A0A6G8AKF2_9BURK/417-511 AC A0A6G8AKF2.1
#=GS R6DIQ9_9BACE/469-581 AC R6DIQ9.1
#=GS A0A7G1G902_9BACT/445-551 AC A0A7G1G902.1
#=GS A0A255T6M6_9BACT/29-141 AC A0A255T6M6.1
#=GS C6L8V3_9FIRM/456-564 AC C6L8V3.1
#=GS A0A5C2HSH3_9GAMM/116-243 AC A0A5C2HSH3.1
#=GS A0A3A8W6H8_UNCXX/460-562 AC A0A3A8W6H8.1
#=GS A0A0D0SG39_9FIRM/425-524 AC A0A0D0SG39.1
#=GS R5TXE2_9BACE/420-512 AC R5TXE2.1
#=GS U6R7P2_9BACT/55-147 AC U6R7P2.1
#=GS A0A1C7H5S8_9BACE/462-573 AC A0A1C7H5S8.1
#=GS E4TGH0_CALNY/413-505 AC E4TGH0.1
#=GS A0A165Z5S7_9EURY/428-524 AC A0A165Z5S7.1
#=GS A0A975GTK7_9BACT/230-350 AC A0A975GTK7.1
#=GS A0A556QXR0_9BACT/481-581 AC A0A556QXR0.1
#=GS A0A098S7T1_9BACT/418-510 AC A0A098S7T1.1
#=GS R7KHR1_9BURK/257-353 AC R7KHR1.1
#=GS R5EZ13_9GAMM/440-538 AC R5EZ13.1
#=GS F9ER57_9FUSO/115-220 AC F9ER57.1
#=GS R6SF59_9FIRM/421-522 AC R6SF59.1
#=GS A0A1W1HKY7_9BACT/416-531 AC A0A1W1HKY7.1
#=GS A0A178IQY3_9BACT/406-494 AC A0A178IQY3.1
#=GS A0A923NPX5_9FIRM/473-574 AC A0A923NPX5.1
#=GS A0A0M9E728_9BACT/7-110 AC A0A0M9E728.1
#=GS A0A3A9GBT1_9FIRM/454-563 AC A0A3A9GBT1.1
#=GS A0A1V1P5S2_9BACT/483-589 AC A0A1V1P5S2.1
#=GS A0A417ECN5_9CLOT/298-371 AC A0A417ECN5.1
#=GS A0A396LCF8_9FIRM/453-555 AC A0A396LCF8.1
#=GS W8KMC6_9GAMM/419-513 AC W8KMC6.1
#=GS A0A4R3Z7X0_9FIRM/196-297 AC A0A4R3Z7X0.1
#=GS A0A3E2TTC0_9FIRM/455-556 AC A0A3E2TTC0.1
#=GS A0A098S6H1_9BACT/407-499 AC A0A098S6H1.1
#=GS A0A2Z6S033_9GLOM/684-791 AC A0A2Z6S033.1
#=GS A0A2P4QS25_RHIID/482-589 AC A0A2P4QS25.1
#=GS R5QKP7_9FIRM/222-331 AC R5QKP7.1
#=GS A0A0M9E676_9BACT/468-592 AC A0A0M9E676.1
#=GS A0A975GHP4_9BACT/440-532 AC A0A975GHP4.1
#=GS A0A174DFH3_9BACE/456-569 AC A0A174DFH3.1
#=GS A0A377GW57_9FUSO/440-544 AC A0A377GW57.1
#=GS A0A416BCS1_9FIRM/458-564 AC A0A416BCS1.1
#=GS A0A5C2HND5_9GAMM/341-467 AC A0A5C2HND5.1
#=GS N2BHK4_9FIRM/1-102 AC N2BHK4.1
#=GS A0A1Y1VWB2_9FUNG/463-563 AC A0A1Y1VWB2.1
#=GS E1VN93_9GAMM/415-508 AC E1VN93.1
#=GS C1DXP0_SULAA/413-507 AC C1DXP0.1
#=GS A0A1Y2FKR5_9FUNG/4-98 AC A0A1Y2FKR5.1
#=GS A0A4R5P242_9BACT/496-594 AC A0A4R5P242.1
#=GS R9KX17_9FIRM/409-519 AC R9KX17.1
#=GS Q2FRK8_METHJ/472-580 AC Q2FRK8.1
#=GS A0A2T5CD97_9BACT/426-518 AC A0A2T5CD97.1
#=GS B1C3U9_9FIRM/1-83 AC B1C3U9.1
#=GS A0A7Y4P6T9_9BURK/424-518 AC A0A7Y4P6T9.1
#=GS A0A2M9A9A3_9BACT/422-523 AC A0A2M9A9A3.1
#=GS R6DU25_9CLOT/454-562 AC R6DU25.1
#=GS A0A662ZG12_9GAMM/513-620 AC A0A662ZG12.1
#=GS H0IZ92_9GAMM/426-520 AC H0IZ92.1
#=GS A0A174BUX1_9FIRM/421-521 AC A0A174BUX1.1
#=GS A0A7C8AAZ8_UNCNT/20-115 AC A0A7C8AAZ8.1
#=GS R7JVY5_9FIRM/23-131 AC R7JVY5.1
#=GS H2J891_MARPK/418-508 AC H2J891.1
#=GS F4L457_HALH1/413-505 AC F4L457.1
#=GS A0A1V1P4W5_9BACT/26-127 AC A0A1V1P4W5.1
#=GS A0A8A7K8E2_9FIRM/483-589 AC A0A8A7K8E2.1
#=GS A0A1Y4NV42_9FIRM/463-565 AC A0A1Y4NV42.1
#=GS A0A0F0CJV4_9BACT/254-361 AC A0A0F0CJV4.1
#=GS A0A0F0CSN3_9BACT/455-562 AC A0A0F0CSN3.1
#=GS A0A414BPD7_9BACT/429-521 AC A0A414BPD7.1
#=GS A6KZF8_PHOV8/2-101 AC A6KZF8.1
#=GS A0A556QVP1_9BACT/312-410 AC A0A556QVP1.1
#=GS A0A2M9A9Y7_9BACT/428-529 AC A0A2M9A9Y7.1
#=GS A0A975AWI1_9THEO/455-561 AC A0A975AWI1.1
#=GS A0A3A8VXF5_UNCXX/198-301 AC A0A3A8VXF5.1
#=GS R5YN53_9FIRM/514-621 AC R5YN53.1
#=GS A0A7Y4LAE5_9BURK/427-521 AC A0A7Y4LAE5.1
#=GS A0A3A8WWF7_UNCXX/447-554 AC A0A3A8WWF7.1
#=GS A0A166AQT4_9EURY/429-525 AC A0A166AQT4.1
#=GS A0A7W2G3N8_9CLOT/452-561 AC A0A7W2G3N8.1
#=GS A0A975GIZ7_9BACT/449-554 AC A0A975GIZ7.1
#=GS U5NA14_9BURK/460-567 AC U5NA14.1
#=GS A0A4Q7DGU5_9RICK/449-554 AC A0A4Q7DGU5.1
#=GS A0A0D0SH26_9FIRM/315-414 AC A0A0D0SH26.1
#=GS A0A166CUC4_9EURY/420-514 AC A0A166CUC4.1
#=GS A0A413I1B3_9FIRM/1-88 AC A0A413I1B3.1
#=GS A0A656HGL8_THINJ/423-517 AC A0A656HGL8.1
#=GS R7JC74_9BACT/421-513 AC R7JC74.1
#=GS A0A0M9EAL4_9BACT/466-579 AC A0A0M9EAL4.1
#=GS A0A3R5X1Q7_9CLOT/416-514 AC A0A3R5X1Q7.1
#=GS A0A374VMJ5_9FIRM/452-556 AC A0A374VMJ5.1
#=GS A0A3Q9FSY5_9BACT/452-560 AC A0A3Q9FSY5.1
#=GS A0A1Y1ZKJ1_9FUNG/131-216 AC A0A1Y1ZKJ1.1
#=GS E5BG88_9FUSO/443-548 AC E5BG88.1
#=GS A0A1W1H9Y6_9BACT/430-522 AC A0A1W1H9Y6.1
#=GS R9KSM2_9FIRM/454-563 AC R9KSM2.1
#=GS E8LK93_SUCHY/87-183 AC E8LK93.1
#=GS A0A7G9GIS0_9FIRM/26-120 AC A0A7G9GIS0.1
#=GS A0A174GKS0_9FIRM/420-519 AC A0A174GKS0.1
#=GS A0A120A465_BACSE/420-512 AC A0A120A465.1
#=GS A0A377GW87_9FUSO/455-560 AC A0A377GW87.1
#=GS U5N9Q4_9BURK/416-510 AC U5N9Q4.1
#=GS C6LKU5_9FIRM/462-565 AC C6LKU5.1
#=GS A0A264Y6P1_9BACT/422-517 AC A0A264Y6P1.1
#=GS A0A7L6AUS2_9GAMM/457-564 AC A0A7L6AUS2.1
#=GS A0A1C7H1I3_9BACE/421-514 AC A0A1C7H1I3.1
#=GS Q82T16_NITEU/416-510 AC Q82T16.1
#=GS A0A165ZSI3_9EURY/419-513 AC A0A165ZSI3.1
#=GS R5JP97_9BACE/20-133 AC R5JP97.1
#=GS A0A255SY75_9BACT/462-574 AC A0A255SY75.1
#=GS A0A4E0RFL3_9GAMM/459-572 AC A0A4E0RFL3.1
#=GS A0A7C8A794_UNCNT/416-511 AC A0A7C8A794.1
#=GS A0A1G9B7Q6_9CLOT/452-544 AC A0A1G9B7Q6.1
#=GS A0A1Y1VW74_9FUNG/454-550 AC A0A1Y1VW74.1
#=GS A0A098S7Z3_9BACT/404-496 AC A0A098S7Z3.1
#=GS M9SIZ5_METAX/442-543 AC M9SIZ5.1
#=GS A0A1H6QPE0_9FIRM/443-544 AC A0A1H6QPE0.1
#=GS A0A1I0XHF3_9CLOT/453-557 AC A0A1I0XHF3.1
#=GS N2B5V8_9FIRM/454-566 AC N2B5V8.1
#=GS R9IUU8_9FIRM/403-503 AC R9IUU8.1
#=GS A0A2N3I8A9_9BACT/459-568 AC A0A2N3I8A9.1
#=GS S3L8N1_9SPIR/438-532 AC S3L8N1.1
#=GS R5TN46_9FIRM/454-562 AC R5TN46.1
#=GS E5CAY9_9BACE/462-573 AC E5CAY9.1
#=GS A0A1H0VL17_9CLOT/415-513 AC A0A1H0VL17.1
#=GS R5GKZ9_9FIRM/45-143 AC R5GKZ9.1
#=GS R6BEZ1_9FIRM/365-461 AC R6BEZ1.1
#=GS A0A0F5IVY4_9BACT/424-516 AC A0A0F5IVY4.1
#=GS A0A7Y9R353_9BURK/422-516 AC A0A7Y9R353.1
#=GS A0A6M0K1N8_9GAMM/415-509 AC A0A6M0K1N8.1
#=GS A0A174AVW0_9FIRM/420-516 AC A0A174AVW0.1
#=GS A0A1V1PF47_9BACT/408-537 AC A0A1V1PF47.1
#=GS R6B824_9BACT/1-79 AC R6B824.1
#=GS R5ELA6_9GAMM/512-619 AC R5ELA6.1
#=GS A0A1W1HA64_9BACT/33-125 AC A0A1W1HA64.1
#=GS R7JU61_9FIRM/454-560 AC R7JU61.1
#=GS A0A5Q0EGS2_9GAMM/415-509 AC A0A5Q0EGS2.1
#=GS A0A1G9IXL3_9CLOT/485-587 AC A0A1G9IXL3.1
#=GS A0A7X3MLL8_9FIRM/1-69 AC A0A7X3MLL8.1
#=GS R5IFS3_9BACT/36-82 AC R5IFS3.1
#=GS R9N778_9FIRM/470-572 AC R9N778.1
#=GS E5BDY5_9FUSO/443-548 AC E5BDY5.1
#=GS U2SU09_9FUSO/454-559 AC U2SU09.1
#=GS A0A4Q7DM63_9RICK/450-555 AC A0A4Q7DM63.1
#=GS A0A166B7D1_9EURY/420-512 AC A0A166B7D1.1
#=GS A0A416GC25_9BACE/425-518 AC A0A416GC25.1
#=GS A0A5C1QH29_9SPIO/418-516 AC A0A5C1QH29.1
#=GS H7EJ16_9SPIR/422-520 AC H7EJ16.1
#=GS A0A3Q9HTA0_9FIRM/459-564 AC A0A3Q9HTA0.1
#=GS Q8A4P4_BACTN/469-581 AC Q8A4P4.1
#=GS A0A4V2E047_9RICK/61-166 AC A0A4V2E047.1
#=GS A0A1H8D3N8_UNCXX/421-520 AC A0A1H8D3N8.1
#=GS A0A1V4IZL4_9CLOT/452-559 AC A0A1V4IZL4.1
#=GS A0A444JGT6_9BACT/455-571 AC A0A444JGT6.1
#=GS R9MX25_9FIRM/442-543 AC R9MX25.1
#=GS A0A397UGN9_9GLOM/117-225 AC A0A397UGN9.1
#=GS A0A4E0QUW4_9GAMM/27-105 AC A0A4E0QUW4.1
#=GS A0A1H6FIF8_9GAMM/417-514 AC A0A1H6FIF8.1
#=GS A0A1G9P9L4_9CLOT/363-465 AC A0A1G9P9L4.1
#=GS R6G835_9BACE/420-512 AC R6G835.1
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A0A176U2Y4_9FIRM/1-55 ...............................--------.-.-..-.-..---....-...-.-.-..-....-.-..-..-..---.-.-.-.-......-------...............----.-..---..-.......----MK.Y..T..E..E..G....K....S.M...E..S..D.CK....................................AALKQ..I....D....EKN.YT..E..TLYQAG......vKRI.LKYGIACQ.IK.DCKVM--le...............................................
A0A1Y4CAC2_9FIRM/513-618 ..............................v-GENFYHG.F.M..L.G..LCT....M...L.S.G..S....Y.T..T..S..NRE.A.G.E.G......RYDIQIM...............PKTP.-..ALP..G.......ILIELK.-..A..E..K..Q....C....S.Q...E..K..L.EQl.................................akAALEQ..I....N....ERK.YE..V..DMVARG......vSVI.FKYGVAFS.GK.NVAV---av...............................................
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A0A6M0L3B0_9BACT/3-51 ..........................yysyn--------.-.-..-.-..---....-...-.-.-..-....-.-..-..-..---.-.-.-.-......-------...............----.-..---..-.......------.-..-..-..-..-....-....-.-...K..N..Q.KG....................................KALEQ..I....K....EKK.YH..E..KYLNTS.......NEI.IIIGIEFS.KE.DRDICK-f................................................
A0A4Q7DG18_9RICK/1-93 .............................vv--------.-.-..-.-..--G....L...R.G.E..Y....Y.I..R..S..NQE.S.G.L.G......RFDVVML...............-PKQ.S..GRA..A.......ILLEFK.A..T..G..D..S....K....K.L...K..A..K.AQ....................................EGLKQ..V....K....DKQ.YL..E..LFKQNG......vKEV.LAIGLAFC.GK.QMCLVS-e................................................
A0A372R5R8_9GLOM/600-708 ..............................l-HEGWYHA.F.V..L.G..SLA....M...Y.H.GddY....Q.V..I..F..NHE.V.G.L.D......HADIRII...............STNK.E..YNT..N.......ITFEFK.V..A..L..S..E....D....C.D...M..M..E.SCa..................................eKGLNQ..I....D....EKN.YR..A..NTPSHV.......KTI.VEVAIAFH.KK.HAFI---sah..............................................
A0A7G9GMY4_9FIRM/79-176 ...............................KDENSYHV.L.M..L.G..LCI...iV...S.D.S..Y....E.I..M..S..NQE.K.G.Y.G......RADIYLK...............--SK.K..GQR..D.......IVIEMK.Y..A..E..N..D....K....E.D...C..L..L.ASa..................................dKAMTQ..I....L....DKH.YG..D..------.......---.--------.--.-------daikigignhqkkaritw...............................
N2BDB2_9FIRM/453-561 ..............................q-PENFYHG.F.I..L.G..LIA...dL...R.G.I..Y....N.V..S..S..NRE.S.G.E.G......RYDVLLE...............PYDP.Q..IDD..G.......IILEFK.V..F..H..P..N....R....D.N...S..P..E.HTv..................................qTAIRQ..I....I....DKK.YA..V..SLNKRCd.....lDRI.RIYGFAFK.GK.EVLI---dg...............................................
W4M145_9BACT/419-511 ..............................r-HEKYYQT.I.F..Y.L..IFK....-...L.M.G..W....R.I..D..A..EVR.T.N.R.G......RIDAVIE...............----.L..ANH..I.......FLFEFK.-..-..-..-..-....-....-.L...D..G..G.VD....................................DALQQ..I....V....DNA.YA..E..RYRAKG.......KPV.TLIGANFD.SR.TRTIDGW.................................................
C6LJM3_9FIRM/454-561 ..............................e-PERFYHG.F.V..L.G..LLV...dL...G.E.R..Y....V.I..T..S..NRE.S.G.F.G......RYDVMLE...............-PKN.P..ADD..A.......IILEFK.V..R..D..A..Q....E....E.P...D..L..N.ATv..................................qSALQQ..I....E....EKK.YA..E..ALISRGi....ppEKI.RRYGFAFQ.GK.KILI---g................................................
A0A4Y7PR28_9AGAM/492-616 ..............................h-KEKVYQA.L.L..F.G..LLFa..kI...G.G.A..F....Y.V..Q..M..EQE.A.G.A.G......RADITIT...............PRDI.T..KII..G.......FIFELK.R..V..T..V..Y....A....K.T...A..K..N.TRrkrktdqkl..................isdletsvnEAMEQ..L....N....TRN.YR..S..HLPLHV.......EMV.YEFGISFA.GK.KCRVK--gr...............................................
A0A173YUD7_9FIRM/23-121 ...................ndenslsctinl--------.-.-..A.F..YFA....-...R.E.Y..Y....T.I..I..R..ELP.T.G.K.G......FEDICFV..............pRKLH.A..DKP..A.......AVIELK.-..-..-..-..-....-....-.W...D..K..D.AE....................................GAIAQ..I....K....EKR.YA..E..ALKEYH.......GNL.LLAGINYD.RK.TKK----ysc..............................................
A0A1Y4D045_9BACT/466-566 ..............................y-REHFYHS.F.L..L.G..IFM....-...-.L.L..Y....P.V..T..S..NRE.A.G.E.G......FFDLIVQ...............--DE.R..DKR..A.......AVIEVK.R..A..D..S..R....E....E.L...E..A..E.VE....................................KALLQ..I....E....ERQ.YD..T..ELKTRG......yTQI.LHWGMAFY.KK.SCKM---gv...............................................
A0A3E2XRR2_9FIRM/454-566 ..............................e-PERFYHG.F.I..L.G..LIV...eQ...W.E.N..Y....R.I..R..S..NRE.S.G.F.G......RYDVMMI...............PRER.SgkHLP..A.......IVMEFK.V..H..N..S..R....K....E.Q...T..L..E.ETv..................................qAALQQ..I....E....DKH.YD..A..ELLAQGf....kkAQI.HHYGFAFQ.GK.KVLIA--ge...............................................
A0A1Y1VW83_9FUNG/31-130 .......................gnlkhvie--------.-.-..F.A..YFN....A...R.I.H..Y....I.V..N..E..EVS.E.G.K.G......ISDFIFY...............-PKN.K..RQK..V.......IIIELK.-..-..-..-..-....-....-.V...N..G..S.AK....................................EAIKQ..I....H....QKK.YY..N..DLKNRGy.....tGNI.LLVGINLN.KK.QK-----sysckiee.........................................
R6XXP7_9BACT/333-426 ..............................n-YEGHYQQ.E.L..F.I..IFT....L...L.T.H..F....V.V..D..V..EVH.T.P.N.G......RVDVVME...............----.T..EDT..L.......YLIELK.-..-..-..-..-....-....-.L...N..Q..S.AQ....................................AAIQQ..I....N....LKQ.YD..Q..RFARCG.......KPI.VKVGVNFD.AK.KGNIEDW.................................................
M9SE20_METAX/454-552 .............................ys-----YQL.V.L..M.T..MMY...sL...S.R.R..Y....D.I..R..T..ETE.E.G.N.G......RVDMIMI...............-PKA.E..GTT..P.......IILELK.K..V..D..S..E....N....H.L...D..K..G.LD....................................EAMGQ..I....H....EKK.YY..A..GMKGE-.......--T.ILIAIAFW.G-.-------kfprirte.........................................
A0A3E2WHQ0_9FIRM/3-107 ..............................a-KESFYHG.F.L..L.G..VLG....N...M.K.D..Y....I.V..R..S..DRE.G.G.R.W......RSDIVIR...............-SLN.V..KCP..P.......MILELK.S..A..E..T..Y....K....E.L...E..E..A.CD....................................RALNQ..I....K....EKE.YG..S..WLPEEG......yTEV.WNHGIAFY.RK.QCKIKV-e................................................
R5NY48_9BACT/429-521 ..............................d-YEGHYQQ.M.L..Y.I..IFS....-...L.L.G..M....Y.V..D..V..EVR.T.P.R.G......RVDMVMR...............----.T..ATT..L.......YIVELK.-..-..-..-..-....-....-.L...N..Q..S.AE....................................AAMQQ..I....D....LKN.YP..E..RFALCG.......LPV.VKVGINFD.ME.RHTLKDW.................................................
A0A3P2A9N4_9BACE/423-515 ..............................k-TEKHYQT.V.F..Y.L..LFR....-...L.M.G..Q....Y.V..D..A..EVK.S.A.V.G......RADVVVR...............----.M..KDA..V.......YVFEFK.-..-..-..-..-....-....-.F...D..G..T.PE....................................EALAQ..I....E....SKQ.YA..I..PYGAEG.......RRI.VKVGVNFD.SA.TRTIGEW.................................................
A0A5C1QEP8_9SPIO/418-517 ...............................EYEGYYAS.V.L..Y.A..FFS....-...A.I.N..C....D.V..I..P..EDI.T.N.H.G......QVDMTIK...............----.L..GST..I.......CVMEIK.-..-..T..T..T....N....F.E...P..N..S.QN....................................LALKQ..I....Q....DMD.YA..K..KYLGITn.....tTTV.YELGLVFD.MD.KRNLVQ-f................................................
A0A1Y3W5A6_9FIRM/463-564 ..............................r-KENFYHG.M.V..L.G..LLQ....S...Q.G.R..W....R.V..Q..S..NDE.T.G.T.G......YSDISIS...............---T.R..ERT..G.......IVIEIK.-..Y..A..N..D....G....N.L...D..G..A.CA....................................EALKQ..I....E....DRN.YA..E..GLRRRG......mKKI.IKYGMAFY.KK.ECMVVK-a................................................
N2ADW9_9FIRM/459-560 ..............................m-KENFFHG.I.L..L.G..LLG....Y...K.D.T..W....I.V..S..S..NEE.S.G.E.G......YGDILVR...............--SD.E..EEI..G.......IVIEVK.Y..A..E..D..G....R....M.-...E..Q..A.CM....................................EALEQ..I....E....SKR.YE..E..KLLQEG......iEHI.LTYGIACY.KK.RCKV---vl...............................................
E5CHC8_9BACE/469-581 ..............................e-GEAHIKG.F.L..L.A..YLG....M...Y.R.Y..Y....Q.L..Y..P..EYE.L.N.K.G......FADFLFRp............spSVPV.L..PPF..T.......YLLEVK.Y..A..K..A..G....A....S.E...K..E..I.RVl.................................adEARGQ..L....L....RYS.ED..E..LVAEARa.....kGGL.KLITIVWR.SW.ELALLE-e................................................
A0A416BC20_9FIRM/462-565 ..............................e-KEIFYHG.I.L..L.G..LLR....C...E.P.D..W....L.I..Q..S..NIE.S.G.D.G......FVDILIE...............PEN-.-..PDA..G.......ILIELK.Y..A..Q..T..Y....A....G.L...E..K..A.CE....................................KAMNQ..I....R....ELR.YD..E..RLRNED......rNDI.LAYGIAFC.KK.KCKVV--ve...............................................
A0A839JY45_9FIRM/512-619 ..............................g-AEGFYHG.L.T..L.G..LIA...lL...D.N.Q..Y....R.I..K..S..NRE.S.G.D.G......RYDISLI...............PRE-.K..KYP..G.......IIMELK.-..W..K..S..G....L....E.E...A..E..L.EKl.................................siDALGQ..I....D....EKR.YD..L..ELKEEG......iENI.IKLGIAFS.GK.KVVIN--ak...............................................
A0A5Q0EHC4_9GAMM/416-510 ...............................QYEGYWAS.V.F..Y.S..HFA....-...A.L.G..L....D.I..R..L..EDT.T.N.Q.G......RLDMAVL...............----.F..NQQ..I.......YLFEFK.-..-..-..-..-....V....V.E...L..V..P.EG....................................RALEQ..L....K....AKN.YA..E..KYRALN.......QPI.HLIGIEFS.RE.QRNL---vgf..............................................
A0A7G1GBY3_9BACT/445-552 ..............................e-PERFYHG.L.I..L.G..MSV...gL...K.E.K..Y....I.I..K..S..NRE.T.G.L.G......RADVILI...............-PKD.K..TDK..G.......IIIEFK.K..Y..N..R..D....E....D.K...S..L..K.DSa..................................kNGLKQ..I....N....EKK.YE..E..EIKNYG......iNDI.IKVSIAFD.KK.EVEIV--sn...............................................
A0A5C1QHD7_9SPIO/421-516 ..............................n-YEGYYAS.I.F..Y.C..YFT....-...A.L.G..L....D.V..V..A..EDV.T.N.V.G......RIDLTVK...............----.I..EDK..I.......YIMEFK.-..-..-..V..V....E....I.V...T..D..G.N-....................................PAIDQ..I....K....SRK.YY..E..KYIGSC.......SDI.YILGVEFS.KT.DRNIT--ry...............................................
A0A6B9TAA9_9ARCH/34-135 .............................hm--EQSYEL.I.V..A.V..TLK...rL...I.N.G..Y....D.V..R..T..EVQ.S.G.N.G......RTDIVMF...............-SGD.A..DNP..G.......IVIELK.R..A..G..R..P....E....D.L...D..H..A.VD....................................EAISQ..I....H....DHR.YY..N..GMRGR-.......--V.VLYGIAFC.G-.-------vvarvgte.........................................
R9JTS1_9FIRM/536-638 ..............................k-SENSYHM.M.M..L.G..MCA...fM...Y.R.Y..Y....D.V..K..S..NRE.G.G.I.G......RSDILLY...............-AKK.R..PLP..H.......MILEFK.Y..T..K..D..E....G....E.D..lE..E..L.AL....................................EAIGQ..I....K....DKK.YD..A..EMTGV-.......--V.YYIGLA--.--.-------hfgkaaqvkwe......................................
A0A1I1P7Z0_9CLOT/452-559 ..............................e-PERVYHA.F.V..L.G..MLI...sL...S.K.S..Y....E.V..K..S..NKE.S.G.Y.G......RYDVMII...............-PKN.I..SKI..G.......IIIEFK.K..I..D..D..F....L....N.D...T..I..E.EGt..................................qKALKQ..I....E....DKK.YE..T..ELLEKG......iQDI.VKLAIVFK.GK.EIKVT--qg...............................................
R5U669_9FIRM/459-561 ..............................l-KENFYHG.I.L..V.G..ILG....L...K.D.Y..W....G.I..T..S..NRE.T.G.D.G......YSDIVVE...............--TE.N..SQK..G.......IILEVK.Y..A..-..H..D....G....N.L...E..A..A.SQ....................................KAVKQ..I....E....KTN.YA..Q..ELQDEG......iDTI.LKYGIAFY.KK.RCKVE--lk...............................................
A0A3E3I8K1_9FIRM/159-262 ..............................y-KEDYYHG.F.T..A.G..LLK....M...M.D.G..Y....L.I..Q..S..NRE.S.G.L.G......RRDIIIR...............-SAP.Y..EGV..A.......VIIETK.V..A..D..T..Y....A....Q.L...E..E..K.AA....................................EAFAQ..I....E....EKQ.YD..A..ELRLEG......yHTF.IKFGIAFF.KK.LC-----kavs.............................................
A0A7G1G593_9BACT/445-552 ..............................e-PERFYHG.L.I..L.G..MSV...gL...K.E.K..Y....I.I..K..S..NRE.T.G.L.G......RADVILI...............-PKD.K..TDK..G.......IIIEFK.K..Y..N..R..D....E....D.K...S..L..K.DSa..................................kNGLNQ..I....N....EKK.YE..E..EIKSYG......iNNI.IKVSIAFD.KK.EVEII--sn...............................................
A0A2K4ZML8_9FIRM/255-344 ..............................e-PERFYHG.F.V..L.G..LMV...dL...A.D.R..Y....R.I..T..S..NRE.S.G.F.G......RYDVMLE...............-PLK.D..GAP..A.......FVLEFK.V..H..D..S..E....D....E.E...T..L..A.DTv..................................tAALRQ..I....E....EKA.YG..I..LVFADG.......---.--------.--.-------rmi..............................................
A0A975GG18_9BACT/449-554 ..............................e-PEKVYHA.L.V..L.G..MLV...wM...S.F.A..Y....E.I..R..S..NRE.S.G.Y.G......RYDIMMK...............-PKD.L..KKH..G.......IIIEFK.M..I..D..E..E....K....T.P...E..Q..T.LK....................................KAMEQ..I....E....NKK.YA..A..ELEAAG......iKEI.IKIAVAFK.GK.ELWLEH-k................................................
R5UMM2_9FIRM/420-517 ..........................enals-----YTV.S.L..A.L..YAA....-...R.N.F..Y....T.I..H..R..EFA.G.G.K.G......FADMVFL...............PRKK.F.pDKP..A.......LVIELK.-..-..-..-..-....-....-.W...D..H..S.AQ....................................GAITQ..I....K....QKQ.YC..E..SLKEYH.......GNL.LLVGINYD.TK.SRIH---tck..............................................
A0A221KF00_VITFI/411-505 ..............................g-FEGHYAS.V.F..Y.S..HLA....-...A.L.G..L....D.L..R..V..EEA.T.N.H.G......RIDLTLR...............----.F..AGQ..I.......FIFEFK.-..-..-..-..V....L....D.G...D..R..P.DG....................................SALAQ..I....R....DKG.YA..D..KYRSHG.......ELV.HLIGIEFG.RV.ARN----lvg..............................................
#=GC seq_cons ..............................t..Etaaps.h.h..h.u..hhs........t.t.t..a....t.l..p..s..Epc.o.u.p.G......RhDlhlh....................t..pph..s.......hllEhK.........................h...p..t..s.sp....................................pAlpQ..I....c....c+p.Ys..p..phpsps.......ppl.hhlGlsFs.tc.ph.l....................................................
//
