#=GF ID PRP21_like_P
#=GF AC PF12230.12
#=GF DE Pre-mRNA splicing factor PRP21 like protein
#=GF AU Assefa S;0000-0003-2178-533X
#=GF AU Gavin OL;
#=GF SE PFAM-B_2642 (release 23.0)
#=GF GA 28.20 28.20;
#=GF TC 28.50 28.70;
#=GF NC 27.70 27.40;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 8341697
#=GF RT The Saccharomyces cerevisiae PRP21 gene product is an integral
#=GF RT component of the prespliceosome.
#=GF RA Arenas JE, Abelson JN;
#=GF RL Proc Natl Acad Sci U S A. 1993;90:6771-6775.
#=GF RN [2]
#=GF RM 7489498
#=GF RT Mammalian splicing factor SF3a120 represents a new member of the
#=GF RT SURP family of proteins and is homologous to the essential
#=GF RT splicing factor PRP21p of Saccharomyces cerevisiae.
#=GF RA Kramer A, Mulhauser F, Wersig C, Groning K, Bilbe G;
#=GF RL RNA. 1995;1:260-272.
#=GF DR INTERPRO; IPR022030;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This domain family is found in eukaryotes, and is typically
#=GF CC between 212 and 238 amino acids in length. The family is found
#=GF CC in association with Pfam:PF01805. There are two completely
#=GF CC conserved residues (W and H) that may be functionally important.
#=GF CC PRP21 is required for assembly of the prespliceosome and it
#=GF CC interacts with U2 snRNP and/or pre-mRNA in the prespliceosome.
#=GF CC This family also contains proteins similar to PRP21, such as the
#=GF CC mammalian SF3a. SF3a also interacts with U2 snRNP from the
#=GF CC prespliceosome, converting it to its active form.
#=GF SQ 2481
#=GS A0A4S2N6H8_9PEZI/212-456 AC A0A4S2N6H8.1
#=GS A0A6I9K6F3_CHRAS/232-472 AC A0A6I9K6F3.1
#=GS A0A444STC4_ARMVU/219-429 AC A0A444STC4.1
#=GS A0A7L3EFL1_9PASS/207-447 AC A0A7L3EFL1.1
#=GS A0A6A1VYI1_9ROSI/260-476 AC A0A6A1VYI1.1
#=GS A0A2T3ALP6_9PEZI/212-467 AC A0A2T3ALP6.1
#=GS A0A6P6BHS2_DURZI/263-479 AC A0A6P6BHS2.1
#=GS A0A8J2SH94_9STRA/229-295 AC A0A8J2SH94.1
#=GS A0A8C4UBY5_FALTI/229-469 AC A0A8C4UBY5.1
#=GS A0A836EWA3_9HYME/217-463 AC A0A836EWA3.1
#=GS A0A5E4G5L9_PRUDU/267-470 AC A0A5E4G5L9.1
#=GS A0A545VHJ2_9HYPO/206-460 AC A0A545VHJ2.1
#=GS A0A2K5RJ88_CEBIM/232-472 AC A0A2K5RJ88.1
#=GS A0A8B9YTF6_BOSMU/232-472 AC A0A8B9YTF6.1
#=GS A0A2V5H856_ASPV1/205-484 AC A0A2V5H856.1
#=GS A0A364LAD5_9EURO/210-466 AC A0A364LAD5.1
#=GS A0A1B8DZB9_9PEZI/206-457 AC A0A1B8DZB9.1
#=GS A0A8H7GVG8_9ASCO/187-399 AC A0A8H7GVG8.1
#=GS A0A1V2L9B4_CYBFA/220-311 AC A0A1V2L9B4.1
#=GS A0A1Y2ABB1_9PLEO/201-464 AC A0A1Y2ABB1.1
#=GS D3ZQM0_RAT/232-470 AC D3ZQM0.1
#=GS A0A8H4CEN0_COLGL/227-487 AC A0A8H4CEN0.1
#=GS A0A3M2SIB2_9HYPO/206-467 AC A0A3M2SIB2.1
#=GS A0A1Q9D1U4_SYMMI/1822-2076 AC A0A1Q9D1U4.1
#=GS V4VZ98_CITCL/261-477 AC V4VZ98.1
#=GS A0A672YQQ0_9TELE/225-466 AC A0A672YQQ0.1
#=GS W1QHG4_OGAPD/163-373 AC W1QHG4.1
#=GS A0A384L5G3_PLAKH/403-547 AC A0A384L5G3.1
#=GS A0A2I0T725_LIMLA/118-344 AC A0A2I0T725.1
#=GS A0A364N1T2_9PLEO/201-458 AC A0A364N1T2.1
#=GS R1F944_EMIHU/211-294 AC R1F944.1
#=GS A0A5E4FQU8_PRUDU/243-442 AC A0A5E4FQU8.1
#=GS A0A0K3C713_RHOTO/205-421 AC A0A0K3C713.1
#=GS A0A132B4K8_9HELO/206-454 AC A0A132B4K8.1
#=GS A0A8H7MLQ7_9PLEO/196-445 AC A0A8H7MLQ7.1
#=GS A0A835LQ61_9MAGN/217-439 AC A0A835LQ61.1
#=GS A9V640_MONBE/196-438 AC A9V640.1
#=GS A0A452F5T9_CAPHI/232-472 AC A0A452F5T9.1
#=GS A0A5E4QRB5_9NEOP/221-466 AC A0A5E4QRB5.1
#=GS Q7SH93_NEUCR/212-471 AC Q7SH93.1
#=GS U1G176_ENDPU/203-487 AC U1G176.1
#=GS A0A395NYX8_TRIAR/207-471 AC A0A395NYX8.1
#=GS B0X8P5_CULQU/231-485 AC B0X8P5.1
#=GS F6HFR3_VITVI/260-476 AC F6HFR3.1
#=GS A0A830HQX9_9CHLO/226-450 AC A0A830HQX9.1
#=GS G8Y2Z8_PICSO/188-403 AC G8Y2Z8.1
#=GS A0A238BRT4_9BILA/210-438 AC A0A238BRT4.1
#=GS Q5CYJ0_CRYPI/209-431 AC Q5CYJ0.1
#=GS A0A7L2UF31_BALRX/207-447 AC A0A7L2UF31.1
#=GS A0A7E5VFX0_TRINI/226-472 AC A0A7E5VFX0.1
#=GS A0A8J5QUV2_9ASCO/185-396 AC A0A8J5QUV2.1
#=GS A0A7M7R684_APIME/217-464 AC A0A7M7R684.1
#=GS G0PF97_CAEBE/177-391 AC G0PF97.1
#=GS A0A074W445_9PEZI/200-449 AC A0A074W445.1
#=GS A0A7R8H5B6_LEPSM/125-340 AC A0A7R8H5B6.1
#=GS A0A0D9VE74_9ORYZ/253-471 AC A0A0D9VE74.1
#=GS A0A067QI32_ZOONE/331-484 AC A0A067QI32.1
#=GS A0A8X8WQG2_SALSN/262-480 AC A0A8X8WQG2.1
#=GS A0A851YGY6_EOLRO/207-447 AC A0A851YGY6.1
#=GS A0A7K9NI41_9CORV/229-469 AC A0A7K9NI41.1
#=GS A0A2K6GPD1_PROCO/232-471 AC A0A2K6GPD1.1
#=GS A0A8C3NBD9_GEOPR/240-480 AC A0A8C3NBD9.1
#=GS A0A225WPU9_9STRA/231-297 AC A0A225WPU9.1
#=GS A0A7L3NYW5_9DEND/207-447 AC A0A7L3NYW5.1
#=GS A0A314ZEZ5_PRUYE/257-473 AC A0A314ZEZ5.1
#=GS A0A6P6MTE1_CARAU/43-150 AC A0A6P6MTE1.1
#=GS A0A485MMI4_LYNPA/232-472 AC A0A485MMI4.1
#=GS G1XD96_ARTOA/205-452 AC G1XD96.1
#=GS A0A0B1PN73_9BILA/217-466 AC A0A0B1PN73.1
#=GS A0A316VUF2_9BASI/276-546 AC A0A316VUF2.1
#=GS A0A2G5B9W4_COERN/187-400 AC A0A2G5B9W4.1
#=GS A0A7K5XIP2_9CHAR/207-447 AC A0A7K5XIP2.1
#=GS A0A384J4J8_BOTFB/204-454 AC A0A384J4J8.1
#=GS A0A8H3UEG1_VENIN/206-449 AC A0A8H3UEG1.1
#=GS A0A8H3IUS3_9LECA/210-471 AC A0A8H3IUS3.1
#=GS G3YBP5_ASPNA/205-463 AC G3YBP5.1
#=GS Q6CDU9_YARLI/186-410 AC Q6CDU9.1
#=GS A0A8C6Y819_NAJNA/228-468 AC A0A8C6Y819.1
#=GS K8FD13_9CHLO/247-494 AC K8FD13.1
#=GS A0A8H4QPX1_9AGAR/214-462 AC A0A8H4QPX1.1
#=GS A0A803WDQ1_FICAL/229-469 AC A0A803WDQ1.1
#=GS A0A7K7PJM5_ACRAR/231-471 AC A0A7K7PJM5.1
#=GS A0A5N5FDK7_9ROSA/212-401 AC A0A5N5FDK7.1
#=GS A0A7L2BWT4_9PASS/207-447 AC A0A7L2BWT4.1
#=GS A0A178EZL4_TRIRU/366-495 AC A0A178EZL4.1
#=GS A0A815HN28_9BILA/432-519 AC A0A815HN28.1
#=GS L9KVQ1_TUPCH/259-499 AC L9KVQ1.1
#=GS Q6GPA9_XENLA/225-466 AC Q6GPA9.1
#=GS A0A6I9UU87_BACDO/227-396 AC A0A6I9UU87.1
#=GS A0A814ZP21_9BILA/237-521 AC A0A814ZP21.1
#=GS A0A8J5A2M4_9DIPT/224-469 AC A0A8J5A2M4.1
#=GS A0A4Z1JXP0_9HELO/204-454 AC A0A4Z1JXP0.1
#=GS A0A1W4WLH6_AGRPL/220-463 AC A0A1W4WLH6.1
#=GS A0A1J7HJD6_LUPAN/756-892 AC A0A1J7HJD6.1
#=GS A0A4P9ZI66_9ASCO/185-398 AC A0A4P9ZI66.1
#=GS A0A8C9ZVP2_SANLU/220-461 AC A0A8C9ZVP2.1
#=GS SF3A1_DICDI/250-480 AC Q86A14.1
#=GS A0A1B8GTY2_9PEZI/206-421 AC A0A1B8GTY2.2
#=GS R0I7P5_SETT2/201-458 AC R0I7P5.1
#=GS A0A1S4H6A9_ANOGA/231-484 AC A0A1S4H6A9.2
#=GS A0A0J8R729_COCIT/209-474 AC A0A0J8R729.1
#=GS A0A024VKT0_PLAFA/436-616 AC A0A024VKT0.1
#=GS A0A226NEB5_CALSU/229-469 AC A0A226NEB5.1
#=GS A0A7J7UHE8_PIPKU/231-471 AC A0A7J7UHE8.1
#=GS A0A1R3HPI3_9ROSI/258-474 AC A0A1R3HPI3.1
#=GS A0A6J3JWH5_9HYME/217-464 AC A0A6J3JWH5.1
#=GS M2WV09_GALSU/230-428 AC M2WV09.1
#=GS A0A6I9RUW1_ELAGV/264-487 AC A0A6I9RUW1.1
#=GS A0A0L0CQX4_LUCCU/221-478 AC A0A0L0CQX4.1
#=GS V2XGZ6_MONRO/217-462 AC V2XGZ6.1
#=GS A0A8C0JHA9_CANLU/232-472 AC A0A8C0JHA9.1
#=GS A0A2I0VYR4_9ASPA/263-485 AC A0A2I0VYR4.1
#=GS A0A0D1Z3L3_9PEZI/201-442 AC A0A0D1Z3L3.1
#=GS A0A428PVJ0_9HYPO/206-467 AC A0A428PVJ0.1
#=GS A0A8J7P0U4_ATRSP/225-466 AC A0A8J7P0U4.1
#=GS R9P2S8_PSEHS/248-470 AC R9P2S8.1
#=GS A0A8H7CJF6_9AGAR/211-456 AC A0A8H7CJF6.1
#=GS A0A420IN32_9PEZI/206-454 AC A0A420IN32.1
#=GS A0A0B2X2C1_METAS/206-470 AC A0A0B2X2C1.1
#=GS A0A0G2FWZ8_9PEZI/213-474 AC A0A0G2FWZ8.1
#=GS A0A251L1V5_MANES/256-472 AC A0A251L1V5.1
#=GS A0A4Z1L592_9HELO/204-454 AC A0A4Z1L592.1
#=GS A0A2T7ND63_POMCA/208-328 AC A0A2T7ND63.1
#=GS A0A0V1HRF0_9BILA/272-517 AC A0A0V1HRF0.1
#=GS A0A452F5V2_CAPHI/232-472 AC A0A452F5V2.1
#=GS A0A821G6T8_9BILA/233-383 AC A0A821G6T8.1
#=GS A0A834ZHG4_9MAGN/260-479 AC A0A834ZHG4.1
#=GS A0A1E4SXZ9_9ASCO/202-415 AC A0A1E4SXZ9.1
#=GS A0A232EZM1_9HYME/238-481 AC A0A232EZM1.1
#=GS B3M2B8_DROAN/222-481 AC B3M2B8.1
#=GS A0A401S0X3_CHIPU/229-471 AC A0A401S0X3.1
#=GS A0A7J8H186_ROUAE/98-272 AC A0A7J8H186.1
#=GS A0A1S4BGC9_TOBAC/258-476 AC A0A1S4BGC9.1
#=GS A0A5M3ZDT8_ASPTE/206-459 AC A0A5M3ZDT8.1
#=GS A0A6P5S4R8_PRUAV/257-456 AC A0A6P5S4R8.1
#=GS A0A0L6U837_9BASI/268-523 AC A0A0L6U837.1
#=GS A0A6A4ACB1_9STRA/294-402 AC A0A6A4ACB1.1
#=GS A0A7L2T3X2_POMRU/207-447 AC A0A7L2T3X2.1
#=GS D5G9J5_TUBMM/200-420 AC D5G9J5.1
#=GS A0A8H5SUX2_FUSHE/206-379 AC A0A8H5SUX2.1
#=GS A0A7K4Z5U0_BUCAB/229-469 AC A0A7K4Z5U0.1
#=GS G1STH0_RABIT/232-472 AC G1STH0.1
#=GS A0A1V6PV40_9EURO/249-499 AC A0A1V6PV40.1
#=GS A0A6P6BHQ1_DURZI/263-479 AC A0A6P6BHQ1.1
#=GS A0A7J6RM99_PEROL/1-104 AC A0A7J6RM99.1
#=GS A0A1V1T3U0_9FUNG/205-470 AC A0A1V1T3U0.1
#=GS A0A7J7G9B8_CAMSI/258-476 AC A0A7J7G9B8.1
#=GS A0A445IT96_GLYSO/277-494 AC A0A445IT96.1
#=GS A0A803TUM8_ANOCA/228-471 AC A0A803TUM8.1
#=GS G3B904_CANTC/173-359 AC G3B904.1
#=GS A0A6A4ACB1_9STRA/231-303 AC A0A6A4ACB1.1
#=GS A0A8V0X2H7_CHICK/217-457 AC A0A8V0X2H7.1
#=GS A0A7K9CBZ1_9PICI/229-470 AC A0A7K9CBZ1.1
#=GS A0A2J6KII3_LACSA/252-480 AC A0A2J6KII3.1
#=GS A0A084G6S0_PSEDA/208-321 AC A0A084G6S0.1
#=GS A0A6G1Q0H9_9TELE/223-464 AC A0A6G1Q0H9.1
#=GS A0A653CMS0_CALMS/215-440 AC A0A653CMS0.1
#=GS H2YW43_CIOSA/200-448 AC H2YW43.1
#=GS A0A6G0Z4A9_APHCR/201-459 AC A0A6G0Z4A9.1
#=GS A0A1E3P9T6_WICAA/260-358 AC A0A1E3P9T6.1
#=GS A0A6I9PJ01_9TELE/218-457 AC A0A6I9PJ01.1
#=GS A0A8C6Y8H1_NAJNA/228-468 AC A0A8C6Y8H1.1
#=GS A0A376B4H3_9ASCO/198-412 AC A0A376B4H3.1
#=GS A0A0B1RRM2_OESDE/9-135 AC A0A0B1RRM2.1
#=GS A0A0D2BDE6_9EURO/201-465 AC A0A0D2BDE6.1
#=GS A0A1E4TDZ0_9ASCO/176-292 AC A0A1E4TDZ0.1
#=GS A0A6H5H689_9HEMI/215-471 AC A0A6H5H689.1
#=GS A0A182EGZ2_ONCOC/211-450 AC A0A182EGZ2.1
#=GS A0A166XGU3_METRR/206-469 AC A0A166XGU3.1
#=GS A0A0J0XPN5_9TREE/238-458 AC A0A0J0XPN5.1
#=GS H7C1L2_HUMAN/2-156 AC H7C1L2.1
#=GS A0A1Q5UG76_9EURO/204-452 AC A0A1Q5UG76.1
#=GS A0A3B6FLI5_WHEAT/244-462 AC A0A3B6FLI5.1
#=GS A0A0F7ZZJ9_9HYPO/201-474 AC A0A0F7ZZJ9.1
#=GS A0A8C3AEU9_CYCLU/219-462 AC A0A8C3AEU9.1
#=GS A0A383W7F8_TETOB/402-535 AC A0A383W7F8.1
#=GS A0A091VI67_OPIHO/207-447 AC A0A091VI67.1
#=GS A0A2J6S6M7_9HELO/206-472 AC A0A2J6S6M7.1
#=GS A0A2V0NVY6_9CHLO/259-528 AC A0A2V0NVY6.1
#=GS A0A803KUL6_CHEQI/4-117 AC A0A803KUL6.1
#=GS A0A8J5A6W9_9CHEL/217-455 AC A0A8J5A6W9.1
#=GS A0A8W8IIT3_CRAGI/1-217 AC A0A8W8IIT3.1
#=GS A0A165GEY2_EXIGL/217-463 AC A0A165GEY2.1
#=GS L5L4U5_PTEAL/232-472 AC L5L4U5.1
#=GS B9SR88_RICCO/265-480 AC B9SR88.1
#=GS A0A8C8M461_ONCTS/204-445 AC A0A8C8M461.1
#=GS A0A5C6N0S8_9TELE/219-458 AC A0A5C6N0S8.1
#=GS A0A1L9VJW7_ASPGL/206-454 AC A0A1L9VJW7.1
#=GS E2ATB4_CAMFO/240-488 AC E2ATB4.1
#=GS A0A2K6SSY7_SAIBB/116-356 AC A0A2K6SSY7.1
#=GS A0A1V8SBR5_9PEZI/204-435 AC A0A1V8SBR5.1
#=GS A0A210QXZ6_MIZYE/215-467 AC A0A210QXZ6.1
#=GS A0A7M7PD72_STRPU/216-366 AC A0A7M7PD72.1
#=GS I1NFU9_SOYBN/253-469 AC I1NFU9.1
#=GS T1EEI0_HELRO/357-540 AC T1EEI0.1
#=GS A0A1V6PIK6_PENDC/204-453 AC A0A1V6PIK6.1
#=GS A0A2S4KY06_9HYPO/202-472 AC A0A2S4KY06.1
#=GS F2SH82_TRIRC/210-349 AC F2SH82.1
#=GS M2ST20_COCSN/201-458 AC M2ST20.1
#=GS A0A0T6BDR3_9SCAR/218-322 AC A0A0T6BDR3.1
#=GS F1NU16_CHICK/229-469 AC F1NU16.2
#=GS A0A672JKQ8_SALFA/219-460 AC A0A672JKQ8.1
#=GS A0A061E8Y3_THECC/264-480 AC A0A061E8Y3.1
#=GS A0A0F8BDG8_LARCR/221-462 AC A0A0F8BDG8.1
#=GS A1CJB2_ASPCL/204-461 AC A1CJB2.1
#=GS M4DJL0_BRARP/163-378 AC M4DJL0.1
#=GS A0A7K9UK97_ANSSE/207-447 AC A0A7K9UK97.1
#=GS A0A4T0J1Z8_WALIC/242-458 AC A0A4T0J1Z8.1
#=GS A0A7J8BZQ7_MOLMO/232-472 AC A0A7J8BZQ7.1
#=GS J4UII9_BEAB2/206-462 AC J4UII9.1
#=GS A0A2U3Y7P1_LEPWE/187-427 AC A0A2U3Y7P1.1
#=GS H1VEG2_COLHI/207-468 AC H1VEG2.1
#=GS A0A4S8J917_MUSBA/315-537 AC A0A4S8J917.1
#=GS A0A369HE02_9HYPO/198-442 AC A0A369HE02.1
#=GS A0A218VT88_PUNGR/256-467 AC A0A218VT88.1
#=GS A0A7L3VNG6_MOLAT/232-472 AC A0A7L3VNG6.1
#=GS A0A8H4VVT2_9HELO/206-456 AC A0A8H4VVT2.1
#=GS A0A1E3HU34_9TREE/237-459 AC A0A1E3HU34.1
#=GS A0A6I9UAZ7_SESIN/265-483 AC A0A6I9UAZ7.1
#=GS A0A8H4V5W8_9HYPO/201-467 AC A0A8H4V5W8.1
#=GS A0A8C3JR51_9CHAR/229-469 AC A0A8C3JR51.1
#=GS A0A835EMU3_9POAL/261-478 AC A0A835EMU3.1
#=GS A0A3D8SIQ1_9EURO/203-460 AC A0A3D8SIQ1.1
#=GS A0A067EU36_CITSI/261-477 AC A0A067EU36.1
#=GS A0A8C3WLJ0_9CETA/232-472 AC A0A8C3WLJ0.1
#=GS A0A158NLL3_ATTCE/217-463 AC A0A158NLL3.1
#=GS A0A2P6QSR5_ROSCH/258-473 AC A0A2P6QSR5.1
#=GS A0A2P6TTX4_CHLSO/225-468 AC A0A2P6TTX4.1
#=GS A0A2K5E5M0_AOTNA/232-472 AC A0A2K5E5M0.1
#=GS A0A1L0G5Z1_9ASCO/174-381 AC A0A1L0G5Z1.1
#=GS A0A2H3GSH8_FUSOX/207-470 AC A0A2H3GSH8.1
#=GS S7RYH0_GLOTA/217-467 AC S7RYH0.1
#=GS A0A3N4I6R5_ASCIM/279-327 AC A0A3N4I6R5.1
#=GS A0A6P6BHQ9_DURZI/263-479 AC A0A6P6BHQ9.1
#=GS A0A0V1MZ67_9BILA/225-470 AC A0A0V1MZ67.1
#=GS F7AI93_CIOIN/220-465 AC F7AI93.2
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A0A8H8DKZ4_9FUNG/405-522 ..........................................tga------------.-------------..------.....-..-.........-.--...............-...............AA.YN.A..IDWHDFV...V....VE.T.VE....F..TE........A............D...E..A....L.......D................L.R.P...........P...M....S.I.M....E....LQ...TM.T..........LAQ..K.R.MA.Al....................................................................................saAV.TI.P.E.S..P.D...D..I...E....E.....E...P..T....EA.....P..A..A...P..V.V.AT...............TP.T.T..P.A.GLSTs................hrK-Pen.............................................................gpTAVK..I.R..T.D..Y.V..P..KA.-.---.----.--.-.----..........................---------.----------................-------..-..-------.....................-.-.-.-..-.-.-.--....-.-.-...-..-------------lvgka..................................................................................
A0A8H5QX83_9HYPO/207-470 .............................................NINDKFLVLNRA.KQRAEYAKYVESE..KQKKEE.....E..E.........V.KA...............K...............EE.FA.M..IDWGDFV...V....VE.T.IT....F..NE........A............D...E..H....A.......N................L.P.P...........P...T....N.L.S....D....LQ...YA.S..........LED..R.N.NA.Sisaslrieeampdedttynaypnqpap................................yptapqqpayqpaqmpppvqpyspvpqaQP.QQ.P.Q.R..S.A...Q..E...E....E.....E...E..R....RI.....Q..E..R...A..E.Q.QA...............RK.Q.Q..-.-.-ATA...................EARg..............................................................gaPPMK..I.K..E.N..Y.V..P..RA.A.QKA.ANRQ.GA.Q.--TA..........................LCPNCKQQI.PMNELEAHMR................IELLDPR..W..KEQKAKA.....................-.-.D.T..R.Y.A.SS....N.T.I...H..VDVANNLKRLASQ.......................................................................................
A0A7K7V996_EUDEL/229-469 ............................................e-AENPKEVLDQV.YYRVEWAKFQERE..RKKEEE.....E..K.........E.KE...............R...............VA.YA.Q..IDWHDFV...V....VE.T.VD....F..QP........-............N...E..Q....G.......N................F.P.P...........P...T....T.P.E....E....LG...AR.I..........LIQ..E.R.YE.Kf.....................................................................................gES.EE.V.E.M..E.V...E..S...D....E.....E...D..E....KQ.....E..K..T...D..E.A.PP...............QP.D.Q..D.T.QVQDmd..............egsD-Dedegqkipppp..........................................dtpmppplpptpDQVI..V.R..K.D..Y.D..P..KA.S.KPL.PPAP.AP.D.EYL-..........................VSPITGEKI.PASKMQEHMR................IGLLDPR..W..LEQRDRS....................iR.E.K.Q..S.D.D.EV....Y.A.P...G..LDIESSLKQLAER.......................................................................................
A0A3N4LBJ7_9PEZI/199-444 .............................................NVKDKYSILERA.RKRAEWSKYQEAQ..KKKAEE.....E..D.........D.AE...............R...............LA.YA.Q..LDWHDFV...V....VE.T.VV....F..TE........A............D...D..A....A.......D................L.P.P...........P...T....T.L.S....D....LQ...YA.S..........LEQ..K.A.MM.Slhsnqlrieeamptsd.......................................................psdyqyhppnqhqyitEE.GA.M.D.V..E.M...E..A...E....S.....D...H..E....DE.....E..I..T...R..T.R.ER...............RE.A.Q..Q.R.Q--Ql.................aQAEak............................................................giaGPMK..I.R..S.D..Y.V..P..RA.A.AAA.ASRR.GV.-.-QMS..........................VCPNCQQQI.PINEMEEHMR................IELLDPR..W..KEQRARA.....................-.-.E.A..R.S.A.TT....N.L.A...V..NDAAANLKRLASQ.......................................................................................
A0A8H7R145_9FUNG/199-411 ............................................n-ITDKYHILERV.KERVEWVVWQEAE..KKKKND.....E..D.........E.KE...............R...............IA.YA.S..IDWHDFV...V....VE.T.VE....F..TD........A............D...E..K....S.......D................L.P.P...........P...M....S.L.S....E....LE...NM.S..........LAQ..K.R.LA.S.......................................................................................--.MP.E.A.A..E.V...E..N...N....S.....Q...P..D....DV.....D..M..D...Q..S.D.DE...............GQ.Q.P..H.V.QAPKip..............dttSSS.................................................................APIK..I.R..A.D..Y.K..P..KL.Y.GTT.PTKG.PS.A.TA--..........................LCPRCGEAI.PVHELDEHMR................IELLDPK..W..KDQKMAM.....................E.A.K.Q..R.D.S.NL....L.Q.E...G..NDIAKILKNI---sg.....................................................................................
A0A7K9Z1M6_9GALL/229-469 ............................................e-AENPKEVLDQV.YYRVEWAKFQERE..RKKEEE.....E..K.........E.KE...............R...............VA.YA.Q..IDWHDFV...V....VE.T.VD....F..QP........-............N...E..Q....G.......N................F.P.P...........P...T....T.P.E....E....LG...AR.I..........LIQ..E.R.YE.Kf.....................................................................................gES.EE.V.E.M..E.V...E..S...D....E.....E...D..E....KQ.....E..K..T...D..E.T.PA...............QL.D.Q..D.T.QVQDmde.............gsdD-Edesqkvppppe...........................................apippplpptpDQVI..V.R..K.D..Y.D..P..KA.S.KPL.PPAP.AP.D.EYL-..........................VSPITGEKI.PASKMQEHMR................IGLLDPR..W..LEQRDRS....................iR.E.K.Q..S.D.D.EV....Y.A.P...G..LDIESSLKQLAER.......................................................................................
A0A7J6LNK5_PERCH/222-481 ............................................y-AKDKSSIVDRV.MGRFQYDEQEARR..KADKEQ.....R..E.........K.EE...............R...............IQ.MA.A..VDWHSFV...V....VE.T.ID....F..KA........E............D...D..E....L.......P................L.P.P...........P...I....L.G.T....T....GK...RP.V..........SEA..P.Q.TL.Vgsaqaaravisk...............................................................ekeviggggagaGP.TF.V.Q.E..E.E...E..M...E....I.....E...D..E....GE.....E..M..Q...M..D.D.MP...............PE.M.A..K.V.ASTSamra..........dverqD-Eeeeeppae................................................alplpelapAPAV..V.R..T.D..Y.H..R..KP.K.RAV.ESSE.DD.-.GRLV..........................KCPITGQMI.RASELSEHLR................VVLLDPK..W..KEQKEKA.....................-.G.H.F..D.I.Q.DT....N.Y.D...Q..ANIESNLASFI--ik.....................................................................................
A0A0M8N2I5_9HYPO/349-471 ..................................naprgpgvaqd------------.-------------..------.....-..-.........-.--...............-...............--.--.-..-------...-....--.-.--....-..--........-............-...-..-....-.......-................-.-.-...........-...-....-.-.-....-....--...--.-..........---..-.-.--.-.......................................................................................--.--.-.-.-..-.-...-..-...-....-.....D...E..E....ES.....R..I..R...E..R.A.AA...............QE.R.-..-.-.AQQA...................QNEar............................................................gglGPMK..I.K..E.N..Y.V..P..RA.A.QKA.GGKQ.G-.-.VPMA..........................LCPNCKQQI.PMNELEAHMR................IELLDPS..W..KEQKAKA.....................-.-.E.S..R.Y.A.SS....N.I.I...H..ADVANNLKRLASQ.......................................................................................
A0A0B7MSX6_9FUNG/200-414 ...........................................nk--DNKYHILERV.KERVEWVAWQEAE..KKKKND.....E..D.........E.KE...............R...............LA.YA.S..IDWHDFV...I....VE.T.VE....F..TD........A............D...E..Q....A.......D................L.P.P...........P...M....S.L.S....E....LE...NM.S..........LAQ..K.R.LA.A......................................................................................mPT.EA.M.Q.Q..P.G...T..K...D....V.....E...P..E....DV.....D..M..E...E..S.D.DE...............ST.-.Q..P.-.AVQPvmp.............kmpDTS.................................................................APIK..I.R..T.D..Y.K..P..KL.Y.GTT.ANKG.AV.A.TE--..........................RCPRCGEAI.PVAEMAEHMR................IELLDPK..W..KEQKMAM.....................E.A.K.Q..R.D.S.NL....L.Q.E...G..NDVAKILKNI---sg.....................................................................................
F0VQA6_NEOCL/228-489 ..........................................ags----TQKALSRC.VKRYAWEADQEKK..RKEKEA.....K..Q.........A.EE...............R...............VQ.MQ.S..IEWHDFF...I....VE.T.ID....F..TE........E............D...D..M....L.......P................L.A.A...........P...M....D.F.S....A....TA...KR.P..........PPA..T.L.AT.Ldgedeepkpdttiaalireaadave.....................................gveedemetedsaeaasaqpeepapPA.EE.P.E.A..E.K...E..K...K....A.....H...E..E....ER.....E..E..S...E..E.E.EE...............RS.P.Q..P.-.---Tg................saAPK.................................................................KSIR..V.V..R.D..Y.I..R..QP.R.KRA.GAAA.EA.P.QQSL.........................qKCPITGQLV.PADQMSNHLR................VLLLDPK..W..KEQKERF.....................L.E.K.A..K.A.E.SA....F.A.P...M..EDVEGNLALFVSK.......................................................................................
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A0A4U6XLX1_9PEZI/207-468 .............................................NIDDKYHVLSRA.KQRAEYSKFQETE..KQKKEE.....E..D.........E.KK...............K...............LE.FA.R..IDWNDFV...V....VE.T.II....F..TD........A............D...E..H....A.......N................L.P.P...........P...T....N.L.S....E....LQ...YA.S..........LEE..R.N.KA.Sitnlrieeamptdedanynaypqtsh..................................sqtlpvhtgyapqqpyqaqapaghqsyQN.EP.P.Q.R..S.A...E..E...E....E.....E...E..R....RI.....Q..E..R...T..E.A.RN...............RE.Q.Q..A.R.AEAR...................GGS.................................................................APMK..I.K..E.N..Y.V..P..RA.L.QRA.ANKQ.SV.-.-QMA..........................LCPNCKQQI.PMDELQDHMR................IELLDPQ..W..KDQKAKS.....................-.-.E.A..R.Y.A.TT....N.L.S...T..ADVANNLKRLASQ.......................................................................................
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A0A8H7AP24_9EURO/203-344 ............................................n-LQDKFRILERA.KQRSEWVKYQEAQ..KQQKEE.....E..E.........E.AE...............R...............VA.YA.Q..IDWHDFV...V....VE.T.VL....F..TE........A............D...D..Q....A.......D................L.P.P...........P...T....S.L.N....D....LQ...SA.S..........LEQ..K.A.MM.Slarp...............................................................................dmriEE.AM.P.T.D..D.M...T..S...Y....Y.....D...P..Y....AQ.....Q..A..Q...T..Q.-.--...............--.-.-..-.-.----...................---.................................................................----..-.-..-.-..-.-..-..--.-.---.----.--.-.----..........................---------.----------................-------..-..-------.....................-.-.-.-..-.-.-.--....-.-.-...-..-------------pyypspspyqpqpqlqqyastmdyt..............................................................
G3VLV5_SARHA/208-446 ......................................tklveqy---------TKV.CYRVEWAKFQERE..RKKEEE.....E..K.........E.KE...............R...............VA.YA.Q..IDWHDFV...V....VE.T.VD....F..QP........-............N...E..Q....G.......N................F.P.P...........P...T....T.P.E....E....LG...AR.I..........LIQ..E.R.YE.Kf.....................................................................................gES.EE.V.E.M..E.V...E..S...D....D.....E...D..Q....KQ.....E..K..T...E..E.P.PS...............QL.D.Q..D.T.QVQDmd..............egsD-Deeegqkvpppp..........................................etpmppplpptpDQVI..V.R..K.D..Y.D..P..KA.S.KPL.PPAP.AP.D.EYL-..........................VSPITGEKI.PASKMQEHMR................IGLLDPR..W..LEQRDRS....................iR.E.K.Q..S.D.D.EV....Y.A.P...G..LDIESSLKQLAER.......................................................................................
A0A7L0DIU7_9CHAR/173-413 ............................................e-AENPKEVLDQV.YYRVEWAKFQERE..RKKEEE.....E..K.........E.KE...............R...............VA.YA.Q..IDWHDFV...V....VE.T.VD....F..QP........-............N...E..Q....G.......N................F.P.P...........P...T....T.P.E....E....LG...AR.I..........LIQ..E.R.YE.Kf.....................................................................................gES.EE.V.E.M..E.V...E..S...D....E.....E...D..E....KQ.....E..K..T...D..E.P.PA...............QL.D.Q..D.T.QVQDmd..............egsD-Dedegqkvpppp..........................................etpmppplpptpDQVI..V.R..K.D..Y.D..P..KA.S.KPL.PPAP.AP.D.EYL-..........................VSPITGEKI.PASKMQEHMR................IGLLDPR..W..LEQRDRS....................iR.E.K.Q..S.D.D.EV....Y.A.P...G..LDIESSLKQLAER.......................................................................................
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A0A0G4J4N3_PLABS/252-375 ............................................e-LNDSSIVQEEI.LGRIEYERIQERL..SGEREM.....E..D.........E.AE...............R...............VA.IG.S..IDWHDFV...V....LR.T.VD....F..TD........-............D...E..N....T.......F................L.P.A...........P..fH....T.I.E....E....IN...RA.Lda.....qdrLAA..N.Q.AS.A.......................................................................................ME.RD.T.E.M..D.M...E..M...E....P.....I...D..D....DT.....R..A..S...A..G.R.PA...............AE.K.-..-.-.----...................---.................................................................----..-.-..-.-..-.-..-..--.-.---.----.--.-.----..........................---------.----------................-------..-..-------.....................-.-.-.-..-.-.-.--....-.-.-...-..-------------qadr...................................................................................
A0A7L1NTI5_RHICY/229-469 ............................................e-AENPKEVLDQV.YYRVEWAKFQERE..RKKEEE.....E..K.........E.KE...............R...............VA.YA.Q..IDWHDFV...V....VE.T.VD....F..QP........-............S...E..Q....G.......N................F.P.P...........P...T....T.P.E....E....LG...AR.I..........LIQ..E.R.YE.Kf.....................................................................................gES.EE.V.E.M..E.V...E..S...D....E.....E...D..E....KQ.....E..K..A...E..E.P.PA...............QL.D.Q..D.T.QVQDmd..............egsD-Dedegqkvpppp..........................................etpmppplpptpDQVI..V.R..K.D..Y.D..P..KA.S.KPL.PPAP.AP.D.EYL-..........................VSPITGEKI.PASKMQEHMR................IGLLDPR..W..LEQRDRS....................iR.E.K.Q..S.D.D.EV....Y.A.P...G..LDIESSLKQLAER.......................................................................................
I2K0G6_DEKBR/28-142 ...........................................nf---DQTKFLDRC.FARAEHDKKVKSD..LSKELK.....D..E.........E.QK...............R...............LY.YA.S..IDWQDFS...V....VQ.K.IE....F..TD........L............D...D..A....A.......A................L.P.A...........P...L....E.K.S....E....LE...FR.S..........LVQ..K.R.AS.Tm.....................................................................................iEE.AP.P.D.Y..D.-...-..-...-....A.....E...D..N....KE.....X..L..K...S..E.K.X-...............--.-.-..-.-.----...................---.................................................................----..-.-..-.-..-.-..-..--.-.---.----.--.-.----..........................---------.----------................-------..-..-------.....................-.-.-.-..-.-.-.--....-.-.-...-..-------------estscxf................................................................................
L0PBT9_PNEJ8/206-442 .............................................NIENKYQLLEVI.RKRVAWQKYQEEQ..QKLKQE.....E..E.........D.RE...............K...............IE.YA.Q..IDWHDFV...V....VE.T.IE....F..TN........A............D...E..Q....M.......D................L.P.A...........P...I....S.L.S....I....LQ...SA.T..........LEQ..K.Q.MM.Tmyhdpnislfddtpyn.......................................................piqpyststekvqslqEE.EG.V.E.M..D.I...E..A...D....S.....D...E..E....TA.....A..I..R...E..R.R.EH...............QE.K.V..R.F.AQQQ..................sRAG.................................................................LPMK..I.R..T.N..Y.V..P..KV.L.NKT.ENML.--.-.----..........................ICPQCNLPI.PSNELEEHMR................IEMLDPK..W..KEQKAKA.....................-.-.E.S..K.S.A.SS....N.L.Y...Q..EGAASNLKRMT--as.....................................................................................
#=GC seq_cons ............................................p..ps.hpVL-ps.hhRsEWt+aQEpp..+pKcE-.....E..t.........E.pE...............R...............ls.aA.p..IDWHDFV...V....VE.T.l-....F..ps.....................s...E..p....s.......s................h.P.P...........P...s....o...p....E....lt...st............Lhp..c.p.ht.p.......................................................................................t..tp.s.t....c.s...-......-..........-...-..-....cp.....p..t..t...p..c.t..t...............p..p.t..t.t.tstp...................t.p.................................................................sthh..l.+..c.-..Y.s..P..+s.p.t.t.sst..ss.................................lsPlsGppI.PsschpEHMR................ItLLDP+..W..hEQ+-+..........................c.p..p.p.p.ps....h.t.s...s...-ltssLKpLApp.......................................................................................
//
