#=GF ID   Pox_RNA_Pol_22
#=GF AC   PF05273.17
#=GF DE   Poxvirus RNA polymerase 22 kDa subunit
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_6584 (release 7.7)
#=GF GA   25.00 25.00;
#=GF TC   44.00 43.50;
#=GF NC   24.50 20.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF DR   INTERPRO; IPR007937;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of several poxvirus DNA-dependent RNA
#=GF CC   polymerase 22 kDa subunits.
#=GF SQ   40
#=GS A0A1C9HHD8_LSDV/1-183   AC A0A1C9HHD8.1
#=GS Q0GNY8_HSPV/1-183       AC Q0GNY8.1
#=GS RP22_VAR67/1-183        AC P33054.1
#=GS RP22_VACCC/1-183        AC P68608.1
#=GS G3EIF4_9POXV/1-183      AC G3EIF4.1
#=GS A0A223FNC9_9POXV/1-183  AC A0A223FNC9.1
#=GS Q08FS4_DPV83/1-183      AC Q08FS4.1
#=GS A0A097IVU2_9POXV/1-183  AC A0A097IVU2.1
#=GS B2CWH3_9POXV/1-183      AC B2CWH3.1
#=GS Q9Q905_RFVKA/1-183      AC Q9Q905.1
#=GS D3IZK1_9POXV/1-184      AC D3IZK1.1
#=GS Q6TUU6_YMTV5/1-183      AC Q6TUU6.1
#=GS Q6TVR6_ORFSA/1-184      AC Q6TVR6.1
#=GS RP22_VACCW/1-183        AC P68609.1
#=GS F1AX39_ORFV/1-184       AC F1AX39.1
#=GS RP22_FOWPN/2-185        AC Q85280.1
#=GS H6TA59_9POXV/1-183      AC H6TA59.1
#=GS A0A3F2YKM5_SHEVT/1-183  AC A0A3F2YKM5.1
#=GS A0A223FMT8_9POXV/1-183  AC A0A223FMT8.1
#=GS Q77TK6_VACCT/1-183      AC Q77TK6.1
#=GS A0A0H4Y107_9POXV/1-186  AC A0A0H4Y107.1
#=GS Q9DHP4_YLDV/1-183       AC Q9DHP4.1
#=GS A0A2C9DT43_9POXV/1-184  AC A0A2C9DT43.1
#=GS A0A1V0QGV6_CNPV/2-185   AC A0A1V0QGV6.1
#=GS A0A2U9QHR7_9POXV/1-183  AC A0A2U9QHR7.1
#=GS RP22_MYXVL/1-183        AC P68546.1
#=GS A0A6B9R1J9_9POXV/1-183  AC A0A6B9R1J9.1
#=GS Q070F4_CPRVZ/1-185      AC Q070F4.1
#=GS U3UBH6_9POXV/1-182      AC U3UBH6.1
#=GS A0A1L3IZI5_9POXV/1-42   AC A0A1L3IZI5.1
#=GS A0A0M3ZRQ1_9POXV/2-185  AC A0A0M3ZRQ1.1
#=GS Q85288_MCV1/1-185       AC Q85288.1
#=GS Q775U9_CAMPS/1-183      AC Q775U9.1
#=GS Q8V3M9_SWPV1/1-183      AC Q8V3M9.1
#=GS A0A220T6D3_9POXV/1-183  AC A0A220T6D3.1
#=GS A0A385H9T2_FOWPV/2-185  AC A0A385H9T2.1
#=GS M1L514_MONPV/1-183      AC M1L514.1
#=GS Q6VZG7_CNPV/2-185       AC Q6VZG7.1
#=GS Q08FA4_DPV84/1-183      AC Q08FA4.1
#=GS A0A1B1MRC0_9POXV/1-183  AC A0A1B1MRC0.1
A0A1C9HHD8_LSDV/1-183              ...MNPHNVKYLAKILCLKTEILKNPYAIISKDVVLRYNTTIKYGDLVTYITVQHKIDATKTLFQVF.NESSVTYSPLENDYGF.PIIIT.....SFLQTGHNKFPINFLYIDIVAS.DLFPKFVRLTDEEIVTVQSVLQIGDSKES-.LKLPKMLETEIAAKILFHKDIPLKIIRFFRNNIITGIEISDRAVITV.
Q0GNY8_HSPV/1-183                  ...MNQYNVKYLAKILCLKTEIARDPYAVINRNVLLRYTTDIEYNDLVTLITVRHKIDSMKTVFQVF.NESSINYTPVDDDYGE.PIIIT.....SYLQKGHNKFPVNFLYIDVVIS.DLFPSFVRLDTTETNIVNSVLQTGDGKKT-.LRLPKMLETEIVVKILYRPNIPLKIVRFFRNNMVTGVEIADRSVISV.
RP22_VAR67/1-183                   ...MNQYNVKYLAKILCIKTEIARDPYAVINRNVLLRYTTDIQYNDLVTLITVRHKIDSMKTVFQVF.NESSINYTPVDDDYGE.PIIIT.....SYLQKGHNKFPVNFLYIDVVIS.DLFPSFVRLNTTETNIVNSVLQTGDGKKT-.LRLPKMLETEIVVKILYRPNIPLKIVRFFRNNMITGVEIADRSVISV.
RP22_VACCC/1-183                   ...MNQYNVKYLAKILCLKTEIARDPYAVINRNVLLRYTTDIEYNDLVTLITVRHKIDSMKTVFQVF.NESSINYTPVDDDYGE.PIIIT.....SYLQKGHNKFPVNFLYIDVVIS.DLFPSFVRLDTTETNIVNSVLQTGDGKKT-.LRLPKMLETEIVVKILYRPNIPLKIVRFFRNNMVTGVEIADRSVISV.
G3EIF4_9POXV/1-183                 ...MNQHNVKYLAKILCLKTEIIRDPYAIISKNVILRYDTDIQYNDLITLITVKHKIDSLKTVFQVF.NESSVNYKPIDDDYGE.PIIIT.....SFLQKGHNKFPINFLYIDIVAS.DLFPTFVRLDESDTVIVNSVLQTGDGKKT-.LRLPKMLETEIAVKILYRSNIPLKIVRFFRNNIVTGIEIADRSVISV.
A0A223FNC9_9POXV/1-183             ...MNQYNVKYLAKILCLKTEIARDPYAVISKNVILRYDTDIDYNDLVTLITVKHKIDSIKTVFQVF.NESSVNYKPVDDDYGE.PIIIT.....SFLQKGHNKFPVNFLYIDMVCS.DLFPTFVRLDAVETAIVNSVLQTGDGKKT-.LRLPKMLETEIAVKILYRPNIPLKIVRFFRNNIVTGIEIADRSVISV.
Q08FS4_DPV83/1-183                 ...MNQHNVKYLAKILCLKTEVLRNPYAIISKDILSKYYTEIKYDDLITIITVIHKIDSEKVVFQVF.NESSVLYNPVEKDYGY.PIIIT.....SFLQMGHNKFPAHFLYIDIVAS.DLFPKFVRLTPDEINIVNSVLQIGDSKDS-.LKLPKMLETEISAKILFHKDYPLKIIRFFRNNMVTGLEISDRVLITV.
A0A097IVU2_9POXV/1-183             ...MNQHNVKYLAKILCLKTEVLRNPYAIISRDILYKYDYDVVYGDLITIITVSHKIESYKIVFQVF.NESSIVYTPIENDYGY.PIIIT.....SFNQPGHNKIPVNFLYIDVVAS.DLFPRFVRLTPDEISVVHSVLAIGDGKES-.LKLPKMLETELSAKILYHKDIPLKIIRFFNGNMVTGVEISDRSIVSV.
B2CWH3_9POXV/1-183                 ...MNPHNVKYLAKILCLKAEIQKNPYAVISKDVVHRYSTDIRYGDLTTIISVRHKTSTSNTVFQVF.NESSVNYTPVDNDYGY.PIIIT.....SFLQTGHNKFPISFLYIDVVAS.DVFPKFARLSPTDVATVYSVLQIGDTKDA-.LKLPRMLETEISAKILFHKDFPLKIVRFFKNNMVTGEEISDRSLVAV.
Q9Q905_RFVKA/1-183                 ...MNPHNVKYLAKILCLKAEIQKNPYAVISKDVVHKYSTDICYGDLTTIIAVHHKTSTSKTVFQVF.NESSVNYTPVDDDYGY.PIIIT.....SFLQTGHNKFPISFLYIDVVAS.DMFPRFARLSPTDIVTVHSVLQIGDTKDV-.LKLPRMLETEISAKILFHKDLPLKIVRFFKHNMVTGEEISDRSLVAV.
D3IZK1_9POXV/1-184                 ...MNRHNTRYLAKILCLKAAVRDDPFAVISRDTVRMYDIAVEYGDLVSVVTVTHRLETSRTVFQVF.NETSVAYSPLPDDYGE.PIVLT.....TYMQREHTKFPLSMLYIDVVAS.DMFPTFKRPTEEEAAVVAAMQRVGGRREAA.LKLPRMLDTELVCKILHLPDHPLRVVRFLRRNMFTGVEIADRSVSVV.
Q6TUU6_YMTV5/1-183                 ...MNNHNVKYLAKILCLKAEITRDPYAIISKEVIFKYETEINYGDLVTIITVKHKIDYSKTVFQVF.NESSVTYYPLENDYGE.PIIIT.....SLLQTGHNKFPISFLYIDLVAS.DLFPKFVRLTQDEINIVHSVLQVGDGKET-.LKLPKMLETEVSAKILYRKDIPLKVIRFFRNNMVTGVEVADRSVVSV.
Q6TVR6_ORFSA/1-184                 ...MNRHNTRYLAKILCLKAAVRSDPFAVVSRDTVRMYDIKVEYGDLVTVVTVTHKLETSRTVFQVF.NETSVAYSPLPDDYGE.PIVLT.....TYMQREHTKFPLSMLYIDVVAS.DMFPTFKRPTEEEAAVVAAMQRVGGRREAV.LKLPRMLDTELVCKILHLPEHPLRVVRFLRRNMFTGVEVADRSVSVV.
RP22_VACCW/1-183                   ...MNQYNVKYLAKILCLKTEIARDPYAVINRNVLLRYTTDIEYNDLVTLITVRHKIDSMKTVFQVF.NESSINYTPVDDDYGE.PIIIT.....SYLQKGHNKFPVNFLYIDVVIS.DLFPSFVRLDTTETNIVNSVLQTGDGKKT-.LRLPKMLETEIVVKILYRPNIPLKIVRFFRNNMVTGVEIADRSVISV.
F1AX39_ORFV/1-184                  ...MNRHNTRYLAKILCLKAAVRSDPFAVVSRDTVRMYDIEVEYGDLVTVVTVTHKLETSRTVFQVF.NETSVAYSPLPDNYGE.PIVLT.....TYMQREHTKFPLSMLYIDVVAS.DMFPTFKRPTEEEAAVVAAMQRVGGRREAV.LKLPRMLDTELVCKILHLPEHPLRVVRFLRRNMFTGVEVADRSVSVV.
RP22_FOWPN/2-185                   ...MNQYNVTYLSKILCLKTEILYKPFSIINRSIVNQYNIDVKYDDITSIVKIRHKTENTILVFQIF.NESNVKYSPIEYDYGD.PIIIT.....SNLQHGHNRIPINMLYIDVVES.DMFPTFSRLDSETIKIITSILQSDNKKEQS.IKLPKVSENELSVKILYHKDYPLKYVRYYKNNMVTGIEVIDRSVAI-t
H6TA59_9POXV/1-183                 ...MNQHNVKYLAKILCLKTEVLRNPYAIISRDILYKYDYDVVYGDLITIITVSHKIESYKIVFQVF.NESSIVYTPIENDYGY.PIIIT.....SFNQPGHNKIPVNFLYIDVVAS.DLFPRFVRLTPDEISVVHSVLAIGDGKES-.LKLPKMLETELSAKILYHKDIPLKIIRFFNGNMVTGVEISDRSIVSV.
A0A3F2YKM5_SHEVT/1-183             ...MNPHNVKYLAKILCLKTEILKNPYAIISKDVVLRYNTTIKYGDLVTYITVQHKIDATKTLFQVF.NESSVTYSPLEDDYGF.PIIIT.....SFLQTGHNKFPINFLYIDIVAS.DLFPKFVRLTDEEIVTVQSVLQIGDSKES-.LKLPKMLETEIAAKILFHKDIPLKIIRFFRNNIITGIEISDRAVINV.
A0A223FMT8_9POXV/1-183             ...MNQYNVKYLAKILCLKTEIARDPYAVISKNVILRYDTDIDYNDLVTLITVKHKIDSIKTVFQVF.NESSVNYKPVEDDYGE.PIIIT.....SFLQKGHNKFPVNFLYIDMVCS.DLFPTFVRLDAVETAIVNSVLQTGDGKKT-.LRLPKMLETEIAVKILYRPNIPLKIVRFFRNNIVTGIEIADRSVISV.
Q77TK6_VACCT/1-183                 ...MNQYNVKYLAKILCLKTEIARDPYAVINRNVLLRYTTDIEYNDLVTLITVRHKIDSMKTVFQVF.NESSINYTPVDDDYGE.PIIIT.....SYLQKGHNKFPVNFLYIDVVIS.DLFPSFVRLDTTETNIVNSVLQTGDGKKT-.LRLPKMLETEIVVKILYRPNIPLKIVRFFRNNMVTGVEIADRSVISV.
A0A0H4Y107_9POXV/1-186             mdl--QNSVKYLGNILSLKVVLKENPTMLVSSKMLRFCTKNIESIENLHRIDINYNNGAAKYSFYVTtSEKTITIPDPPEGYTNwPSVIRiglsdNVLYYDPNTYGIKSLCFDVVNSsSMFIPFSPLTDPEQKKLLS---KS---VKK.LQLPKMHFSELPCKICEGAVSSFKIMEFYLPNMDSGIEKYYRKII--y
Q9DHP4_YLDV/1-183                  ...MNNHNVKYLAKILCLKAEISRDPYATISKDVILKYETEINYGDLVTTITVKHKIDYVKTVFQVF.NESSVAYSPVENDYGE.PIIIT.....SFLQTGHNKFPINFLYIDLVAS.DLFPKFVRLTQDEINIVNSVLQVGDGKET-.LKLPKMLETEISAKILYRKDTPLKVIRFFRNNMVTGVEVADRSVVSV.
A0A2C9DT43_9POXV/1-184             ...MNQHNVRYLAKILCLKAEVARNPYALIEREVIRRYSVETRYGDIVTVITVSHRLDNAVVVFQVF.NEATVSYSPVEYDYGE.PIIIT.....QFPQVAHNRFPVSLLYIDLVES.DQFPRFSRMDPETLKVVTSLLQSEDRRTDS.LRLPRMLETEITAKILYRRDLPLKVVRFYKNNMVTGIEISDRLVANV.
A0A1V0QGV6_CNPV/2-185              ...MNQYNVSYLSKILCLKAEILYRPFSVISKNILKHYYIDVEYKDIGSIVKTRHKTDNIITVFQIF.NESNIKYVPVEYDYGE.PIIIT.....SSLQQGHNKIPINVLYIDTVES.DMFPVFSRVDKSDSKIISDILQSENKKEPS.LRLPKVADTELSIKILYHKDYPLKYVRYYKNNIMTGIEFMDRAVIA-t
A0A2U9QHR7_9POXV/1-183             ...MNKYNVTYLSKILCLKAEILRDPFAIISSEVLLRYDINISYGDLVSVIRVIHKIDSSITVFQVF.NETTINYTPIDNDYGQ.PIIIT.....SFLQTEPNKFPISFLYIDVIAS.DLFPRFKRPTQEEMNIITNVLNTGNKKES-.LKLPRMLDTEIVAKILYHQDYPLKIVRFFRNNIITGVEIADRSIANV.
RP22_MYXVL/1-183                   ...MNPHNVKYLAKILCLKAEIQKNPYAVISKDVVHRYSTDIRYGDLTTIISVRHKTSTSNTVFQVF.NESSVNYTPVDNDYGY.PIIIT.....SFLQTGHNKFPISFLYIDVVAS.DVFPKFARLSPTDVATVYSVLQIGDTKDA-.LKLPRMLETEISAKILFHKDFPLKIVRFFKNNMVTGEEISDRSLVAV.
A0A6B9R1J9_9POXV/1-183             ...MNQNSVKYLAKILCLKTEVARNPYAVISKDVLLRYNIDIKYSDLITTIVVRHKIDSFSLVFQVF.NESSINYTPVENDYGE.PIILT.....TYLQNGHNKFPISALYIDIVIS.DLFPCFSRLDEEENSIIASILQIGDSKVS-.LKLPKMLETEITAKILYNKNIPLKTIRFYRNNKITGLEIMDRAVVSV.
Q070F4_CPRVZ/1-185                 ...MNSYNVNYMAKVFCLKTEILRDPFAVISSQTLDKYDARVQFGEVVSVITVTNRVDGDPTVYQLF.HETVVNYAPKKDDYGE.PMLLT.....AYKLPEHNKFPMSMTSIDVVAS.SIFPRFSRPTPSDVSVIECMLMQDDPKSKTrLKLSKMLSTELVCKILYHRDHPLKYVRFYKNNRQTGVEVYDRQVMNV.
U3UBH6_9POXV/1-182                 ...MNPYNVRYLAKILCLKAEIVRDPYAVISRDVLGKYTIETRYSDLSTRVTVTHKVDARVTVFQVF.NEASVSYSPVEHDYGE.PIIIT.....AFTQSGHNRFPVSFLYVDAVSS.DLFPTFSRLTPKETAVVSTMLQVDG-KEQ-.LRLPRMLETELVAKILHHPNLQLKIVRFYRRNMITGIEVADRAVVAV.
A0A1L3IZI5_9POXV/1-42              ...----------------------------------------------------------------.----------------.-----.....----------------------.------------------------------.-----MLETELSAKILYHKDIPLKIIRFFNGNIVTGVEISDRSIISV.
A0A0M3ZRQ1_9POXV/2-185             ...MNQYNVKYLSKILCMKAEILYKPFSTISKNIIKQYNIDVRYNDIRSIVTVTHKIDNNVTVFQVF.NESTITYVPVEYDYGE.PIIIT.....SNTQPGHNRIPIHILYIDVVAS.DMFPTFSRLDKETTKIVTSILQSDNKKEQS.IKLPKVSDTELSAKILYHKEYPLKFIRYYKHNMVTGIEIIDRAVIS-l
Q85288_MCV1/1-185                  ...MNQHNVEYLAKILCLKAEVARNPYVVVSKELLSRYDVRTRYGDLVTLVRVTHRVDNSTTVFQVF.NEAAVSYTPLEHDYGE.PIIVT.....AFALPAHNKFPVSALYIDMVAS.DLFPRFARVDPDTAKVITSLLTPEDRRNEQpVRLPRMLETEVVAKILYHPKVPLKIVRFYKPNMLTGVELADRAVAAV.
Q775U9_CAMPS/1-183                 ...MNQYNVKYLAKILCLKTEIARDPYAVINRNVLLRYTTDIQYNDLVTLITVRHKIDSMKTVFQVF.NESSINYTPVDDDYGE.PIIIT.....SYLQKGHNKFPVNFLYIDVVIS.DLFPSFVRLDTTETNIVNNVLQTGDGKKT-.LRLPKMLETEIVVKILYRPNIPLKIVRFFRNNMVTGVEIADRSVISV.
Q8V3M9_SWPV1/1-183                 ...MNPHNVKYLAKILCLKTEILRNPYSVISKDILSKYITDIKYGDLVTYITICHKIDSSKVLYQVF.NESSVIYTPLENDYGY.PIIIT.....SFLQVGHNKFPINFLYIDMVAS.DLFPKFVRLTPDEITTVQSVLQIGDSRDS-.LKLPKMLETEIAAKILFHNDIPLKMIRFFRNNIVTGVEVSDRSIVTV.
A0A220T6D3_9POXV/1-183             ...MNPHNVKYLAKILCLKTEILRDPYAIISRDILSHYNTNIKYGDLISIVTVSHKIDSMITNYQIF.NETAVTYTPIENDYGE.PIIIT.....TYLQSGHNKFPINFLYIDVVIS.DMFPKFVRLKPDEASAVSSMLQIGSSKES-.LKLPKMLETELVAKILYRPNMPLKIVRFYRNNMVTGIEIADRAIVAV.
A0A385H9T2_FOWPV/2-185             ...MNQYNVTYLSKILCLKTEILYKPFSIINRSIVNQYNIDVKYDDITSIVKIRHKTENTILVFQIF.NESNVKYSPIEYDYGD.PIIIT.....SNLQHGHNRIPINMLYIDVVES.DMFPTFSRLDSETIKIITSILQSDNKKEQS.IKLPKVSENELSVKILYHKDYPLKYVRYYKNNMVTGIEVIDRSVAI-t
M1L514_MONPV/1-183                 ...MNQYNVKYLAKILCLKTEIARDPYAVINRNVLLRYTTDIEYNDLVTLITVRHKIDSMKTVFQVF.NESSINYTPVDDDYGE.PIIIT.....SYLQKGHNKFPVNFLYIDVVIS.DLFPSFVRLDTTETNIVNSVLQTGDGKKT-.LRLPKMLETEIVVKILYRPNIPLKIVRFFRNNMVTGVEIADRSVISV.
Q6VZG7_CNPV/2-185                  ...MNQYNVSYLSKILCLKAEISYRPFSVISKNIIKQYYIDVEYKDIGSIVKTRHKTDNAITVFQIF.NESNIKYSPIEYDYGE.PIIIT.....ANLQQGHNKIPINMLYVDTVES.DMFPVFSRLDKNETRIISDILHSEDKKEPS.LRLPKVADTELSVKILYHKDYPLKYVRYYKNNIMTGLEFIDRVVVI-t
Q08FA4_DPV84/1-183                 ...MNQHNVKYLAKILCLKTEVLRNPYAIISKDILSKYYTEIKYDDLITIITVIHKIDSEKVVFQVF.NESSVLYNPVEKDYGY.PIIIT.....SFLQMGHNKFPAHFLYIDIVAS.DLFPKFVRLTPDEINTVNSVLQIGDSKDS-.LKLPKMLETEISAKILFHKDYPLKIIRFFRNNMVTGLEISDRVLITV.
A0A1B1MRC0_9POXV/1-183             ...MNKHNIKYLAKILCLKAKVAHDPFATISKDVLSMYDITTNYGDIVSIVTVVHKIDTKVTVFQVF.NEASVNYSPINNDYGV.PIIIT.....SYLQPEHNKFPISFLYIDAVAS.DLFPTFKRLTQEEYTTVTSVLLTGNKKES-.LKLPRMLDTELSAKILYHKEYPAKIIRFFRSNLVTGLEIADRSVANV.
#=GC seq_cons                      ...MNpaNVKYLAKILCLKsEIhRcPYAlIS+sllh+Yss-IcYsDLlTlITVpHKIDoh+TVFQVF.NESSVsYoPl-sDYGE.PIIIT.....SaLQpGHNKFPlsFLYIDlVsS.DLFPpFsRLsssEhslVsSVLQsGDsK-s..L+LPKMLETElssKILY+p-hPLKIVRFFRNNMVTGlEIuDRSVluV.
//